T Cell Factor 1-Expressing Memory-like CD8+ T Cells Sustain the Immune Response to Chronic Viral Infections

Immunity

Volumn 45, Issue 2, 2016, Pages 415-427

  Utzschneider, Daniel T ^a,e   Charmoy, Mélanie ^b   Chennupati, Vijaykumar ^b   Pousse, Laurène ^b   Ferreira, Daniela Pais ^b   Calderon Copete, Sandra ^b   Danilo, Maxime ^b   Alfei, Francesca ^a,f   Hofmann, Maike ^c   Wieland, Dominik ^c,d   Pradervand, Sylvain ^b   Thimme, Robert ^c   Zehn, Dietmar ^a,f   Held, Werner ^b  

^a LAUSANNE UNIVERSITY HOSPITAL   (Switzerland)

^b UNIVERSITY OF LAUSANNE   (Switzerland)

^c UNIVERSITY OF FREIBURG   (Germany)

^d UNIVERSITY OF FREIBURG   (Germany)

^e UNIVERSITY OF CALIFORNIA   (United States)

^f TECHNICAL UNIVERSITY OF MUNICH   (Germany)

Author keywords

chronic infection; differentiation of cytotoxic T cells; LCMV; PD 1; T cell exhaustion; T cell memory; Tcf1

Indexed keywords

PROGRAMMED DEATH 1 LIGAND 1; TRANSCRIPTION FACTOR 7; CD223 ANTIGEN; LEUKOCYTE ANTIGEN; PDCD1 PROTEIN, MOUSE; PROGRAMMED DEATH 1 RECEPTOR; TRANSCRIPTOME;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BACTERIAL ARTIFICIAL CHROMOSOME; BLOOD; CD8+ T LYMPHOCYTE; CELL EXPANSION; CELL SELF-RENEWAL; CONTROLLED STUDY; EFFECTOR CELL; EXON; IMMUNE RESPONSE; LYMPHOCYTE DIFFERENTIATION; LYMPHOCYTE PROLIFERATION; MEMORY; MEMORY CELL; MEMORY T LYMPHOCYTE; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; VIRAL CLEARANCE; VIRUS INFECTION; ADULT; ANIMAL; C57BL MOUSE; CELL AGING; CELL CULTURE; CELL PROLIFERATION; CHRONIC DISEASE; CHRONIC HEPATITIS C; FEMALE; GENETICS; HEPACIVIRUS; HUMAN; IMMUNOLOGICAL MEMORY; IMMUNOLOGY; IMMUNOTHERAPY; LYMPHOCYTIC CHORIOMENINGITIS; LYMPHOCYTIC CHORIOMENINGITIS VIRUS; MALE; METABOLISM; MIDDLE AGED; PROCEDURES; TRANSGENIC MOUSE; VIROLOGY;

ADULT; ANIMALS; ANTIGENS, CD; CD8-POSITIVE T-LYMPHOCYTES; CELL AGING; CELL PROLIFERATION; CELLS, CULTURED; CHRONIC DISEASE; FEMALE; HEPACIVIRUS; HEPATITIS C, CHRONIC; HUMANS; IMMUNOLOGIC MEMORY; IMMUNOTHERAPY; LYMPHOCYTIC CHORIOMENINGITIS; LYMPHOCYTIC CHORIOMENINGITIS VIRUS; MALE; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MIDDLE AGED; PROGRAMMED CELL DEATH 1 RECEPTOR; T CELL TRANSCRIPTION FACTOR 1; TRANSCRIPTOME;

EID: 85002609650     PISSN: 10747613     EISSN: 10974180     Source Type: Journal    
DOI: 10.1016/j.immuni.2016.07.021     Document Type: Article

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