-
1
-
-
84971367738
-
Brief report: Proatherogenic cytokine microenvironment in the aortic adventitia of patients with rheumatoid arthritis
-
Ahmed, A., Hollan, I., Curran, S.A., Kitson, S.M., Riggio, M.P., Mikkelsen, K., Almdahl, S.M., Aukrust, P., McInnes, I.B., Goodyear, C.S., Brief report: Proatherogenic cytokine microenvironment in the aortic adventitia of patients with rheumatoid arthritis. Arthritis Rheumatol. 68 (2016), 1361–1366.
-
(2016)
Arthritis Rheumatol.
, vol.68
, pp. 1361-1366
-
-
Ahmed, A.1
Hollan, I.2
Curran, S.A.3
Kitson, S.M.4
Riggio, M.P.5
Mikkelsen, K.6
Almdahl, S.M.7
Aukrust, P.8
McInnes, I.B.9
Goodyear, C.S.10
-
2
-
-
84933060018
-
DNA methylome signature in synoviocytes from patients with early rheumatoid arthritis compared to synoviocytes from patients with longstanding rheumatoid arthritis
-
Ai, R., Whitaker, J.W., Boyle, D.L., Tak, P.P., Gerlag, D.M., Wang, W., Firestein, G.S., DNA methylome signature in synoviocytes from patients with early rheumatoid arthritis compared to synoviocytes from patients with longstanding rheumatoid arthritis. Arthritis Rheumatol. 67 (2015), 1978–1980.
-
(2015)
Arthritis Rheumatol.
, vol.67
, pp. 1978-1980
-
-
Ai, R.1
Whitaker, J.W.2
Boyle, D.L.3
Tak, P.P.4
Gerlag, D.M.5
Wang, W.6
Firestein, G.S.7
-
3
-
-
84974556019
-
Joint-specific DNA methylation and transcriptome signatures in rheumatoid arthritis identify distinct pathogenic processes
-
Ai, R., Hammaker, D., Boyle, D.L., Morgan, R., Walsh, A.M., Fan, S., Firestein, G.S., Wang, W., Joint-specific DNA methylation and transcriptome signatures in rheumatoid arthritis identify distinct pathogenic processes. Nat. Commun., 7, 2016, 11849.
-
(2016)
Nat. Commun.
, vol.7
, pp. 11849
-
-
Ai, R.1
Hammaker, D.2
Boyle, D.L.3
Morgan, R.4
Walsh, A.M.5
Fan, S.6
Firestein, G.S.7
Wang, W.8
-
4
-
-
33645823916
-
Antibodies to viral citrullinated peptide in rheumatoid arthritis
-
Anzilotti, C., Merlini, G., Pratesi, F., Tommasi, C., Chimenti, D., Migliorini, P., Antibodies to viral citrullinated peptide in rheumatoid arthritis. J. Rheumatol. 33 (2006), 647–651.
-
(2006)
J. Rheumatol.
, vol.33
, pp. 647-651
-
-
Anzilotti, C.1
Merlini, G.2
Pratesi, F.3
Tommasi, C.4
Chimenti, D.5
Migliorini, P.6
-
5
-
-
84867081740
-
Pre-rheumatoid arthritis: predisposition and transition to clinical synovitis
-
Arend, W.P., Firestein, G.S., Pre-rheumatoid arthritis: predisposition and transition to clinical synovitis. Nat. Rev. Rheumatol. 8 (2012), 573–586.
-
(2012)
Nat. Rev. Rheumatol.
, vol.8
, pp. 573-586
-
-
Arend, W.P.1
Firestein, G.S.2
-
6
-
-
84929493316
-
Towards a stratified targeted approach with biologic treatments in rheumatoid arthritis: role of synovial pathobiology
-
Astorri, E., Nerviani, A., Bombardieri, M., Pitzalis, C., Towards a stratified targeted approach with biologic treatments in rheumatoid arthritis: role of synovial pathobiology. Curr. Pharm. Des. 21 (2015), 2216–2224.
-
(2015)
Curr. Pharm. Des.
, vol.21
, pp. 2216-2224
-
-
Astorri, E.1
Nerviani, A.2
Bombardieri, M.3
Pitzalis, C.4
-
7
-
-
84930453993
-
Citrullinated peptide dendritic cell immunotherapy in HLA risk genotype-positive rheumatoid arthritis patients
-
Benham, H., Nel, H.J., Law, S.C., Mehdi, A.M., Street, S., Ramnoruth, N., Pahau, H., Lee, B.T., Ng, J., Brunck, M.E., et al. Citrullinated peptide dendritic cell immunotherapy in HLA risk genotype-positive rheumatoid arthritis patients. Sci. Transl. Med., 7, 2015, 290ra87.
-
(2015)
Sci. Transl. Med.
, vol.7
, pp. 290ra87
-
-
Benham, H.1
Nel, H.J.2
Law, S.C.3
Mehdi, A.M.4
Street, S.5
Ramnoruth, N.6
Pahau, H.7
Lee, B.T.8
Ng, J.9
Brunck, M.E.10
-
8
-
-
80052502019
-
A BAFF/APRIL-dependent TLR3-stimulated pathway enhances the capacity of rheumatoid synovial fibroblasts to induce AID expression and Ig class-switching in B cells
-
Bombardieri, M., Kam, N.W., Brentano, F., Choi, K., Filer, A., Kyburz, D., McInnes, I.B., Gay, S., Buckley, C., Pitzalis, C., A BAFF/APRIL-dependent TLR3-stimulated pathway enhances the capacity of rheumatoid synovial fibroblasts to induce AID expression and Ig class-switching in B cells. Ann. Rheum. Dis. 70 (2011), 1857–1865.
-
(2011)
Ann. Rheum. Dis.
, vol.70
, pp. 1857-1865
-
-
Bombardieri, M.1
Kam, N.W.2
Brentano, F.3
Choi, K.4
Filer, A.5
Kyburz, D.6
McInnes, I.B.7
Gay, S.8
Buckley, C.9
Pitzalis, C.10
-
9
-
-
84893758625
-
Epigenetics in rheumatoid arthritis: a primer for rheumatologists
-
Bottini, N., Firestein, G.S., Epigenetics in rheumatoid arthritis: a primer for rheumatologists. Curr. Rheumatol. Rep., 15, 2013, 372.
-
(2013)
Curr. Rheumatol. Rep.
, vol.15
, pp. 372
-
-
Bottini, N.1
Firestein, G.S.2
-
10
-
-
84871778727
-
Duality of fibroblast-like synoviocytes in RA: passive responders and imprinted aggressors
-
Bottini, N., Firestein, G.S., Duality of fibroblast-like synoviocytes in RA: passive responders and imprinted aggressors. Nat. Rev. Rheumatol. 9 (2013), 24–33.
-
(2013)
Nat. Rev. Rheumatol.
, vol.9
, pp. 24-33
-
-
Bottini, N.1
Firestein, G.S.2
-
11
-
-
84929670608
-
The impact of biological therapy on regulatory T cells in rheumatoid arthritis
-
Byng-Maddick, R., Ehrenstein, M.R., The impact of biological therapy on regulatory T cells in rheumatoid arthritis. Rheumatology (Oxford) 54 (2015), 768–775.
-
(2015)
Rheumatology (Oxford)
, vol.54
, pp. 768-775
-
-
Byng-Maddick, R.1
Ehrenstein, M.R.2
-
12
-
-
84908555221
-
Lungs, joints and immunity against citrullinated proteins in rheumatoid arthritis
-
Catrina, A.I., Ytterberg, A.J., Reynisdottir, G., Malmström, V., Klareskog, L., Lungs, joints and immunity against citrullinated proteins in rheumatoid arthritis. Nat. Rev. Rheumatol. 10 (2014), 645–653.
-
(2014)
Nat. Rev. Rheumatol.
, vol.10
, pp. 645-653
-
-
Catrina, A.I.1
Ytterberg, A.J.2
Reynisdottir, G.3
Malmström, V.4
Klareskog, L.5
-
13
-
-
84950107630
-
Mechanisms involved in triggering rheumatoid arthritis
-
Catrina, A.I., Joshua, V., Klareskog, L., Malmström, V., Mechanisms involved in triggering rheumatoid arthritis. Immunol. Rev. 269 (2016), 162–174.
-
(2016)
Immunol. Rev.
, vol.269
, pp. 162-174
-
-
Catrina, A.I.1
Joshua, V.2
Klareskog, L.3
Malmström, V.4
-
14
-
-
84923614330
-
Potential mechanisms leading to the abnormal lipid profile in patients with rheumatoid arthritis versus healthy volunteers and reversal by tofacitinib
-
Charles-Schoeman, C., Fleischmann, R., Davignon, J., Schwartz, H., Turner, S.M., Beysen, C., Milad, M., Hellerstein, M.K., Luo, Z., Kaplan, I.V., et al. Potential mechanisms leading to the abnormal lipid profile in patients with rheumatoid arthritis versus healthy volunteers and reversal by tofacitinib. Arthritis Rheumatol. 67 (2015), 616–625.
-
(2015)
Arthritis Rheumatol.
, vol.67
, pp. 616-625
-
-
Charles-Schoeman, C.1
Fleischmann, R.2
Davignon, J.3
Schwartz, H.4
Turner, S.M.5
Beysen, C.6
Milad, M.7
Hellerstein, M.K.8
Luo, Z.9
Kaplan, I.V.10
-
15
-
-
84895875371
-
Citrullination regulates pluripotency and histone H1 binding to chromatin
-
Christophorou, M.A., Castelo-Branco, G., Halley-Stott, R.P., Oliveira, C.S., Loos, R., Radzisheuskaya, A., Mowen, K.A., Bertone, P., Silva, J.C., Zernicka-Goetz, M., et al. Citrullination regulates pluripotency and histone H1 binding to chromatin. Nature 507 (2014), 104–108.
-
(2014)
Nature
, vol.507
, pp. 104-108
-
-
Christophorou, M.A.1
Castelo-Branco, G.2
Halley-Stott, R.P.3
Oliveira, C.S.4
Loos, R.5
Radzisheuskaya, A.6
Mowen, K.A.7
Bertone, P.8
Silva, J.C.9
Zernicka-Goetz, M.10
-
16
-
-
84962175403
-
Single cell cloning and recombinant monoclonal antibodies generation from RA synovial B cells reveal frequent targeting of citrullinated histones of NETs
-
Corsiero, E., Bombardieri, M., Carlotti, E., Pratesi, F., Robinson, W., Migliorini, P., Pitzalis, C., Single cell cloning and recombinant monoclonal antibodies generation from RA synovial B cells reveal frequent targeting of citrullinated histones of NETs. Ann. Rheum. Dis. 75 (2016), 1866–1875.
-
(2016)
Ann. Rheum. Dis.
, vol.75
, pp. 1866-1875
-
-
Corsiero, E.1
Bombardieri, M.2
Carlotti, E.3
Pratesi, F.4
Robinson, W.5
Migliorini, P.6
Pitzalis, C.7
-
17
-
-
84997051923
-
Rheumatoid synovial fibroblasts differentiate into distinct subsets in the presence of cytokines and cartilage
-
Croft, A.P., Naylor, A.J., Marshall, J.L., Hardie, D.L., Zimmermann, B., Turner, J., Desanti, G., Adams, H., Yemm, A.I., Müller-Ladner, U., et al. Rheumatoid synovial fibroblasts differentiate into distinct subsets in the presence of cytokines and cartilage. Arthritis Res. Ther., 18, 2016, 270.
-
(2016)
Arthritis Res. Ther.
, vol.18
, pp. 270
-
-
Croft, A.P.1
Naylor, A.J.2
Marshall, J.L.3
Hardie, D.L.4
Zimmermann, B.5
Turner, J.6
Desanti, G.7
Adams, H.8
Yemm, A.I.9
Müller-Ladner, U.10
-
18
-
-
84899534357
-
Periodontal pathogens directly promote autoimmune experimental arthritis by inducing a TLR2- and IL-1-driven Th17 response
-
de Aquino, S.G., Abdollahi-Roodsaz, S., Koenders, M.I., van de Loo, F.A., Pruijn, G.J., Marijnissen, R.J., Walgreen, B., Helsen, M.M., van den Bersselaar, L.A., de Molon, R.S., et al. Periodontal pathogens directly promote autoimmune experimental arthritis by inducing a TLR2- and IL-1-driven Th17 response. J. Immunol. 192 (2014), 4103–4111.
-
(2014)
J. Immunol.
, vol.192
, pp. 4103-4111
-
-
de Aquino, S.G.1
Abdollahi-Roodsaz, S.2
Koenders, M.I.3
van de Loo, F.A.4
Pruijn, G.J.5
Marijnissen, R.J.6
Walgreen, B.7
Helsen, M.M.8
van den Bersselaar, L.A.9
de Molon, R.S.10
-
19
-
-
84896299794
-
Features of the synovium of individuals at risk of developing rheumatoid arthritis: implications for understanding preclinical rheumatoid arthritis
-
de Hair, M.J., van de Sande, M.G., Ramwadhdoebe, T.H., Hansson, M., Landewé, R., van der Leij, C., Maas, M., Serre, G., van Schaardenburg, D., Klareskog, L., et al. Features of the synovium of individuals at risk of developing rheumatoid arthritis: implications for understanding preclinical rheumatoid arthritis. Arthritis Rheumatol. 66 (2014), 513–522.
-
(2014)
Arthritis Rheumatol.
, vol.66
, pp. 513-522
-
-
de Hair, M.J.1
van de Sande, M.G.2
Ramwadhdoebe, T.H.3
Hansson, M.4
Landewé, R.5
van der Leij, C.6
Maas, M.7
Serre, G.8
van Schaardenburg, D.9
Klareskog, L.10
-
20
-
-
78249262113
-
The number of elevated cytokines and chemokines in preclinical seropositive rheumatoid arthritis predicts time to diagnosis in an age-dependent manner
-
Deane, K.D., O'Donnell, C.I., Hueber, W., Majka, D.S., Lazar, A.A., Derber, L.A., Gilliland, W.R., Edison, J.D., Norris, J.M., Robinson, W.H., Holers, V.M., The number of elevated cytokines and chemokines in preclinical seropositive rheumatoid arthritis predicts time to diagnosis in an age-dependent manner. Arthritis Rheum. 62 (2010), 3161–3172.
-
(2010)
Arthritis Rheum.
, vol.62
, pp. 3161-3172
-
-
Deane, K.D.1
O'Donnell, C.I.2
Hueber, W.3
Majka, D.S.4
Lazar, A.A.5
Derber, L.A.6
Gilliland, W.R.7
Edison, J.D.8
Norris, J.M.9
Robinson, W.H.10
Holers, V.M.11
-
21
-
-
84897146058
-
Synovial phenotypes in rheumatoid arthritis correlate with response to biologic therapeutics
-
Dennis, G. Jr., Holweg, C.T., Kummerfeld, S.K., Choy, D.F., Setiadi, A.F., Hackney, J.A., Haverty, P.M., Gilbert, H., Lin, W.Y., Diehl, L., et al. Synovial phenotypes in rheumatoid arthritis correlate with response to biologic therapeutics. Arthritis Res. Ther., 16, 2014, R90.
-
(2014)
Arthritis Res. Ther.
, vol.16
, pp. R90
-
-
Dennis, G.1
Holweg, C.T.2
Kummerfeld, S.K.3
Choy, D.F.4
Setiadi, A.F.5
Hackney, J.A.6
Haverty, P.M.7
Gilbert, H.8
Lin, W.Y.9
Diehl, L.10
-
22
-
-
33846949349
-
Dickkopf-1 is a master regulator of joint remodeling
-
Diarra, D., Stolina, M., Polzer, K., Zwerina, J., Ominsky, M.S., Dwyer, D., Korb, A., Smolen, J., Hoffmann, M., Scheinecker, C., et al. Dickkopf-1 is a master regulator of joint remodeling. Nat. Med. 13 (2007), 156–163.
-
(2007)
Nat. Med.
, vol.13
, pp. 156-163
-
-
Diarra, D.1
Stolina, M.2
Polzer, K.3
Zwerina, J.4
Ominsky, M.S.5
Dwyer, D.6
Korb, A.7
Smolen, J.8
Hoffmann, M.9
Scheinecker, C.10
-
23
-
-
84928637582
-
The rheumatoid arthritis risk gene LBH regulates growth in fibroblast-like synoviocytes
-
Ekwall, A.K., Whitaker, J.W., Hammaker, D., Bugbee, W.D., Wang, W., Firestein, G.S., The rheumatoid arthritis risk gene LBH regulates growth in fibroblast-like synoviocytes. Arthritis Rheumatol. 67 (2015), 1193–1202.
-
(2015)
Arthritis Rheumatol.
, vol.67
, pp. 1193-1202
-
-
Ekwall, A.K.1
Whitaker, J.W.2
Hammaker, D.3
Bugbee, W.D.4
Wang, W.5
Firestein, G.S.6
-
24
-
-
67149084969
-
Immunogenetic risks of anti-cyclical citrullinated peptide antibodies in a North American Native population with rheumatoid arthritis and their first-degree relatives
-
El-Gabalawy, H.S., Robinson, D.B., Hart, D., Elias, B., Markland, J., Peschken, C.A., Smolik, I., Montes-Aldana, G., Schroeder, M., Fritzler, M.J., et al. Immunogenetic risks of anti-cyclical citrullinated peptide antibodies in a North American Native population with rheumatoid arthritis and their first-degree relatives. J. Rheumatol. 36 (2009), 1130–1135.
-
(2009)
J. Rheumatol.
, vol.36
, pp. 1130-1135
-
-
El-Gabalawy, H.S.1
Robinson, D.B.2
Hart, D.3
Elias, B.4
Markland, J.5
Peschken, C.A.6
Smolik, I.7
Montes-Aldana, G.8
Schroeder, M.9
Fritzler, M.J.10
-
25
-
-
84876828211
-
Functional IL6R 358Ala allele impairs classical IL-6 receptor signaling and influences risk of diverse inflammatory diseases
-
Ferreira, R.C., Freitag, D.F., Cutler, A.J., Howson, J.M., Rainbow, D.B., Smyth, D.J., Kaptoge, S., Clarke, P., Boreham, C., Coulson, R.M., et al. Functional IL6R 358Ala allele impairs classical IL-6 receptor signaling and influences risk of diverse inflammatory diseases. PLoS Genet., 9, 2013, e1003444.
-
(2013)
PLoS Genet.
, vol.9
, pp. e1003444
-
-
Ferreira, R.C.1
Freitag, D.F.2
Cutler, A.J.3
Howson, J.M.4
Rainbow, D.B.5
Smyth, D.J.6
Kaptoge, S.7
Clarke, P.8
Boreham, C.9
Coulson, R.M.10
-
26
-
-
84879103564
-
The fibroblast as a therapeutic target in rheumatoid arthritis
-
Filer, A., The fibroblast as a therapeutic target in rheumatoid arthritis. Curr. Opin. Pharmacol. 13 (2013), 413–419.
-
(2013)
Curr. Opin. Pharmacol.
, vol.13
, pp. 413-419
-
-
Filer, A.1
-
27
-
-
0029914194
-
Invasive fibroblast-like synoviocytes in rheumatoid arthritis. Passive responders or transformed aggressors?
-
Firestein, G.S., Invasive fibroblast-like synoviocytes in rheumatoid arthritis. Passive responders or transformed aggressors?. Arthritis Rheum. 39 (1996), 1781–1790.
-
(1996)
Arthritis Rheum.
, vol.39
, pp. 1781-1790
-
-
Firestein, G.S.1
-
28
-
-
0038011833
-
Evolving concepts of rheumatoid arthritis
-
Firestein, G.S., Evolving concepts of rheumatoid arthritis. Nature 423 (2003), 356–361.
-
(2003)
Nature
, vol.423
, pp. 356-361
-
-
Firestein, G.S.1
-
29
-
-
84903178199
-
The disease formerly known as rheumatoid arthritis
-
Firestein, G.S., The disease formerly known as rheumatoid arthritis. Arthritis Res. Ther., 16, 2014, 114.
-
(2014)
Arthritis Res. Ther.
, vol.16
, pp. 114
-
-
Firestein, G.S.1
-
30
-
-
0036169592
-
How important are T cells in chronic rheumatoid synovitis?: II. T cell-independent mechanisms from beginning to end
-
Firestein, G.S., Zvaifler, N.J., How important are T cells in chronic rheumatoid synovitis?: II. T cell-independent mechanisms from beginning to end. Arthritis Rheum. 46 (2002), 298–308.
-
(2002)
Arthritis Rheum.
, vol.46
, pp. 298-308
-
-
Firestein, G.S.1
Zvaifler, N.J.2
-
31
-
-
0030886724
-
Somatic mutations in the p53 tumor suppressor gene in rheumatoid arthritis synovium
-
Firestein, G.S., Echeverri, F., Yeo, M., Zvaifler, N.J., Green, D.R., Somatic mutations in the p53 tumor suppressor gene in rheumatoid arthritis synovium. Proc. Natl. Acad. Sci. USA 94 (1997), 10895–10900.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 10895-10900
-
-
Firestein, G.S.1
Echeverri, F.2
Yeo, M.3
Zvaifler, N.J.4
Green, D.R.5
-
32
-
-
34247855059
-
Contribution for new genetic markers of rheumatoid arthritis activity and severity: sequencing of the tumor necrosis factor-alpha gene promoter
-
Fonseca, J.E., Cavaleiro, J., Teles, J., Sousa, E., Andreozzi, V.L., Antunes, M., Amaral-Turkman, M.A., Canhão, H., Mourão, A.F., Lopes, J., et al. Contribution for new genetic markers of rheumatoid arthritis activity and severity: sequencing of the tumor necrosis factor-alpha gene promoter. Arthritis Res. Ther., 9, 2007, R37.
-
(2007)
Arthritis Res. Ther.
, vol.9
, pp. R37
-
-
Fonseca, J.E.1
Cavaleiro, J.2
Teles, J.3
Sousa, E.4
Andreozzi, V.L.5
Antunes, M.6
Amaral-Turkman, M.A.7
Canhão, H.8
Mourão, A.F.9
Lopes, J.10
-
33
-
-
0034114880
-
Expression of sentrin, a novel antiapoptotic molecule, at sites of synovial invasion in rheumatoid arthritis
-
Franz, J.K., Pap, T., Hummel, K.M., Nawrath, M., Aicher, W.K., Shigeyama, Y., Müller-Ladner, U., Gay, R.E., Gay, S., Expression of sentrin, a novel antiapoptotic molecule, at sites of synovial invasion in rheumatoid arthritis. Arthritis Rheum. 43 (2000), 599–607.
-
(2000)
Arthritis Rheum.
, vol.43
, pp. 599-607
-
-
Franz, J.K.1
Pap, T.2
Hummel, K.M.3
Nawrath, M.4
Aicher, W.K.5
Shigeyama, Y.6
Müller-Ladner, U.7
Gay, R.E.8
Gay, S.9
-
34
-
-
84962375370
-
Baricitinib in patients with refractory rheumatoid arthritis
-
Genovese, M.C., Kremer, J., Zamani, O., Ludivico, C., Krogulec, M., Xie, L., Beattie, S.D., Koch, A.E., Cardillo, T.E., Rooney, T.P., et al. Baricitinib in patients with refractory rheumatoid arthritis. N. Engl. J. Med. 374 (2016), 1243–1252.
-
(2016)
N. Engl. J. Med.
, vol.374
, pp. 1243-1252
-
-
Genovese, M.C.1
Kremer, J.2
Zamani, O.3
Ludivico, C.4
Krogulec, M.5
Xie, L.6
Beattie, S.D.7
Koch, A.E.8
Cardillo, T.E.9
Rooney, T.P.10
-
35
-
-
84992641058
-
Limb bud and heart development gene transcription is regulated by the interplay of an enhancer risk allele and DNA methylation in rheumatoid arthritis
-
Hammaker, D., Whitaker, J.W., Maeshima, K., Boyle, D.L., Ekwall, A.H., Wang, W., Firestein, G.S., Limb bud and heart development gene transcription is regulated by the interplay of an enhancer risk allele and DNA methylation in rheumatoid arthritis. Arthritis Rheumatol. 68 (2016), 2637–2645.
-
(2016)
Arthritis Rheumatol.
, vol.68
, pp. 2637-2645
-
-
Hammaker, D.1
Whitaker, J.W.2
Maeshima, K.3
Boyle, D.L.4
Ekwall, A.H.5
Wang, W.6
Firestein, G.S.7
-
36
-
-
84860561645
-
Induction of osteoclastogenesis and bone loss by human autoantibodies against citrullinated vimentin
-
Harre, U., Georgess, D., Bang, H., Bozec, A., Axmann, R., Ossipova, E., Jakobsson, P.J., Baum, W., Nimmerjahn, F., Szarka, E., et al. Induction of osteoclastogenesis and bone loss by human autoantibodies against citrullinated vimentin. J. Clin. Invest. 122 (2012), 1791–1802.
-
(2012)
J. Clin. Invest.
, vol.122
, pp. 1791-1802
-
-
Harre, U.1
Georgess, D.2
Bang, H.3
Bozec, A.4
Axmann, R.5
Ossipova, E.6
Jakobsson, P.J.7
Baum, W.8
Nimmerjahn, F.9
Szarka, E.10
-
38
-
-
68849105560
-
Expression and function of histone deacetylases in rheumatoid arthritis synovial fibroblasts
-
Horiuchi, M., Morinobu, A., Chin, T., Sakai, Y., Kurosaka, M., Kumagai, S., Expression and function of histone deacetylases in rheumatoid arthritis synovial fibroblasts. J. Rheumatol. 36 (2009), 1580–1589.
-
(2009)
J. Rheumatol.
, vol.36
, pp. 1580-1589
-
-
Horiuchi, M.1
Morinobu, A.2
Chin, T.3
Sakai, Y.4
Kurosaka, M.5
Kumagai, S.6
-
39
-
-
34247227700
-
Histone deacetylase/acetylase activity in total synovial tissue derived from rheumatoid arthritis and osteoarthritis patients
-
Huber, L.C., Brock, M., Hemmatazad, H., Giger, O.T., Moritz, F., Trenkmann, M., Distler, J.H., Gay, R.E., Kolling, C., Moch, H., et al. Histone deacetylase/acetylase activity in total synovial tissue derived from rheumatoid arthritis and osteoarthritis patients. Arthritis Rheum. 56 (2007), 1087–1093.
-
(2007)
Arthritis Rheum.
, vol.56
, pp. 1087-1093
-
-
Huber, L.C.1
Brock, M.2
Hemmatazad, H.3
Giger, O.T.4
Moritz, F.5
Trenkmann, M.6
Distler, J.H.7
Gay, R.E.8
Kolling, C.9
Moch, H.10
-
40
-
-
79957958931
-
Inhibition of HDAC activity by ITF2357 ameliorates joint inflammation and prevents cartilage and bone destruction in experimental arthritis
-
Joosten, L.A., Leoni, F., Meghji, S., Mascagni, P., Inhibition of HDAC activity by ITF2357 ameliorates joint inflammation and prevents cartilage and bone destruction in experimental arthritis. Mol. Med. 17 (2011), 391–396.
-
(2011)
Mol. Med.
, vol.17
, pp. 391-396
-
-
Joosten, L.A.1
Leoni, F.2
Meghji, S.3
Mascagni, P.4
-
41
-
-
84937611249
-
Identification of novel antiacetylated vimentin antibodies in patients with early inflammatory arthritis
-
Juarez, M., Bang, H., Hammar, F., Reimer, U., Dyke, B., Sahbudin, I., Buckley, C.D., Fisher, B., Filer, A., Raza, K., Identification of novel antiacetylated vimentin antibodies in patients with early inflammatory arthritis. Ann. Rheum. Dis. 75 (2016), 1099–1107.
-
(2016)
Ann. Rheum. Dis.
, vol.75
, pp. 1099-1107
-
-
Juarez, M.1
Bang, H.2
Hammar, F.3
Reimer, U.4
Dyke, B.5
Sahbudin, I.6
Buckley, C.D.7
Fisher, B.8
Filer, A.9
Raza, K.10
-
42
-
-
79951515816
-
Smoking is a major preventable risk factor for rheumatoid arthritis: estimations of risks after various exposures to cigarette smoke
-
Källberg, H., Ding, B., Padyukov, L., Bengtsson, C., Rönnelid, J., Klareskog, L., Alfredsson, L., EIRA Study Group. Smoking is a major preventable risk factor for rheumatoid arthritis: estimations of risks after various exposures to cigarette smoke. Ann. Rheum. Dis. 70 (2011), 508–511.
-
(2011)
Ann. Rheum. Dis.
, vol.70
, pp. 508-511
-
-
Källberg, H.1
Ding, B.2
Padyukov, L.3
Bengtsson, C.4
Rönnelid, J.5
Klareskog, L.6
Alfredsson, L.7
-
43
-
-
59249107052
-
DNA methylation profiles in monozygotic and dizygotic twins
-
Kaminsky, Z.A., Tang, T., Wang, S.C., Ptak, C., Oh, G.H., Wong, A.H., Feldcamp, L.A., Virtanen, C., Halfvarson, J., Tysk, C., et al. DNA methylation profiles in monozygotic and dizygotic twins. Nat. Genet. 41 (2009), 240–245.
-
(2009)
Nat. Genet.
, vol.41
, pp. 240-245
-
-
Kaminsky, Z.A.1
Tang, T.2
Wang, S.C.3
Ptak, C.4
Oh, G.H.5
Wong, A.H.6
Feldcamp, L.A.7
Virtanen, C.8
Halfvarson, J.9
Tysk, C.10
-
44
-
-
82555192432
-
DNA methylation regulates the expression of CXCL12 in rheumatoid arthritis synovial fibroblasts
-
Karouzakis, E., Rengel, Y., Jüngel, A., Kolling, C., Gay, R.E., Michel, B.A., Tak, P.P., Gay, S., Neidhart, M., Ospelt, C., DNA methylation regulates the expression of CXCL12 in rheumatoid arthritis synovial fibroblasts. Genes Immun. 12 (2011), 643–652.
-
(2011)
Genes Immun.
, vol.12
, pp. 643-652
-
-
Karouzakis, E.1
Rengel, Y.2
Jüngel, A.3
Kolling, C.4
Gay, R.E.5
Michel, B.A.6
Tak, P.P.7
Gay, S.8
Neidhart, M.9
Ospelt, C.10
-
45
-
-
84922339796
-
Ultrasound-guided synovial biopsy: a safe, well-tolerated and reliable technique for obtaining high-quality synovial tissue from both large and small joints in early arthritis patients
-
Kelly, S., Humby, F., Filer, A., Ng, N., Di Cicco, M., Hands, R.E., Rocher, V., Bombardieri, M., D'Agostino, M.A., McInnes, I.B., et al. Ultrasound-guided synovial biopsy: a safe, well-tolerated and reliable technique for obtaining high-quality synovial tissue from both large and small joints in early arthritis patients. Ann. Rheum. Dis. 74 (2015), 611–617.
-
(2015)
Ann. Rheum. Dis.
, vol.74
, pp. 611-617
-
-
Kelly, S.1
Humby, F.2
Filer, A.3
Ng, N.4
Di Cicco, M.5
Hands, R.E.6
Rocher, V.7
Bombardieri, M.8
D'Agostino, M.A.9
McInnes, I.B.10
-
46
-
-
66049122344
-
Cadherin 11 promotes invasive behavior of fibroblast-like synoviocytes
-
Kiener, H.P., Niederreiter, B., Lee, D.M., Jimenez-Boj, E., Smolen, J.S., Brenner, M.B., Cadherin 11 promotes invasive behavior of fibroblast-like synoviocytes. Arthritis Rheum. 60 (2009), 1305–1310.
-
(2009)
Arthritis Rheum.
, vol.60
, pp. 1305-1310
-
-
Kiener, H.P.1
Niederreiter, B.2
Lee, D.M.3
Jimenez-Boj, E.4
Smolen, J.S.5
Brenner, M.B.6
-
47
-
-
84994126498
-
Update on the genetic architecture of rheumatoid arthritis
-
Kim, K., Bang, S.Y., Lee, H.S., Bae, S.C., Update on the genetic architecture of rheumatoid arthritis. Nat. Rev. Rheumatol. 13 (2017), 13–24.
-
(2017)
Nat. Rev. Rheumatol.
, vol.13
, pp. 13-24
-
-
Kim, K.1
Bang, S.Y.2
Lee, H.S.3
Bae, S.C.4
-
48
-
-
84988842065
-
Elevated IgA plasmablast levels in subjects at risk of developing rheumatoid arthritis
-
Kinslow, J.D., Blum, L.K., Deane, K.D., Demoruelle, M.K., Okamoto, Y., Parish, M.C., Kongpachith, S., Lahey, L.J., Norris, J.M., Robinson, W.H., Holers, V.M., Elevated IgA plasmablast levels in subjects at risk of developing rheumatoid arthritis. Arthritis Rheumatol. 68 (2016), 2372–2383.
-
(2016)
Arthritis Rheumatol.
, vol.68
, pp. 2372-2383
-
-
Kinslow, J.D.1
Blum, L.K.2
Deane, K.D.3
Demoruelle, M.K.4
Okamoto, Y.5
Parish, M.C.6
Kongpachith, S.7
Lahey, L.J.8
Norris, J.M.9
Robinson, W.H.10
Holers, V.M.11
-
49
-
-
0028825348
-
Naturally processed peptides from rheumatoid arthritis associated and non-associated HLA-DR alleles
-
Kirschmann, D.A., Duffin, K.L., Smith, C.E., Welply, J.K., Howard, S.C., Schwartz, B.D., Woulfe, S.L., Naturally processed peptides from rheumatoid arthritis associated and non-associated HLA-DR alleles. J. Immunol. 155 (1995), 5655–5662.
-
(1995)
J. Immunol.
, vol.155
, pp. 5655-5662
-
-
Kirschmann, D.A.1
Duffin, K.L.2
Smith, C.E.3
Welply, J.K.4
Howard, S.C.5
Schwartz, B.D.6
Woulfe, S.L.7
-
50
-
-
84860917533
-
Inflamed target tissue provides a specific niche for highly expanded T-cell clones in early human autoimmune disease
-
Klarenbeek, P.L., de Hair, M.J., Doorenspleet, M.E., van Schaik, B.D., Esveldt, R.E., van de Sande, M.G., Cantaert, T., Gerlag, D.M., Baeten, D., van Kampen, A.H., et al. Inflamed target tissue provides a specific niche for highly expanded T-cell clones in early human autoimmune disease. Ann. Rheum. Dis. 71 (2012), 1088–1093.
-
(2012)
Ann. Rheum. Dis.
, vol.71
, pp. 1088-1093
-
-
Klarenbeek, P.L.1
de Hair, M.J.2
Doorenspleet, M.E.3
van Schaik, B.D.4
Esveldt, R.E.5
van de Sande, M.G.6
Cantaert, T.7
Gerlag, D.M.8
Baeten, D.9
van Kampen, A.H.10
-
51
-
-
85006504169
-
Aggregatibacter actinomycetemcomitans-induced hypercitrullination links periodontal infection to autoimmunity in rheumatoid arthritis
-
Konig, M.F., Abusleme, L., Reinholdt, J., Palmer, R.J., Teles, R.P., Sampson, K., Rosen, A., Nigrovic, P.A., Sokolove, J., Giles, J.T., et al. Aggregatibacter actinomycetemcomitans-induced hypercitrullination links periodontal infection to autoimmunity in rheumatoid arthritis. Sci. Transl. Med., 8, 2016, 369ra176.
-
(2016)
Sci. Transl. Med.
, vol.8
, pp. 369ra176
-
-
Konig, M.F.1
Abusleme, L.2
Reinholdt, J.3
Palmer, R.J.4
Teles, R.P.5
Sampson, K.6
Rosen, A.7
Nigrovic, P.A.8
Sokolove, J.9
Giles, J.T.10
-
52
-
-
84959099710
-
Antibodies to native and citrullinated RA33 (hnRNP A2/B1) challenge citrullination as the inciting principle underlying loss of tolerance in rheumatoid arthritis
-
Konig, M.F., Giles, J.T., Nigrovic, P.A., Andrade, F., Antibodies to native and citrullinated RA33 (hnRNP A2/B1) challenge citrullination as the inciting principle underlying loss of tolerance in rheumatoid arthritis. Ann. Rheum. Dis. 75 (2016), 2022–2028.
-
(2016)
Ann. Rheum. Dis.
, vol.75
, pp. 2022-2028
-
-
Konig, M.F.1
Giles, J.T.2
Nigrovic, P.A.3
Andrade, F.4
-
53
-
-
84939817801
-
Circulating tumour necrosis factor is highly correlated with brainstem serotonin transporter availability in humans
-
Krishnadas, R., Nicol, A., Sassarini, J., Puri, N., Burden, A.D., Leman, J., Combet, E., Pimlott, S., Hadley, D., McInnes, I.B., Cavanagh, J., Circulating tumour necrosis factor is highly correlated with brainstem serotonin transporter availability in humans. Brain Behav. Immun. 51 (2016), 29–38.
-
(2016)
Brain Behav. Immun.
, vol.51
, pp. 29-38
-
-
Krishnadas, R.1
Nicol, A.2
Sassarini, J.3
Puri, N.4
Burden, A.D.5
Leman, J.6
Combet, E.7
Pimlott, S.8
Hadley, D.9
McInnes, I.B.10
Cavanagh, J.11
-
54
-
-
84961966554
-
Identification of a novel chemokine-dependent molecular mechanism underlying rheumatoid arthritis-associated autoantibody-mediated bone loss
-
Krishnamurthy, A., Joshua, V., Haj Hensvold, A., Jin, T., Sun, M., Vivar, N., Ytterberg, A.J., Engström, M., Fernandes-Cerqueira, C., Amara, K., et al. Identification of a novel chemokine-dependent molecular mechanism underlying rheumatoid arthritis-associated autoantibody-mediated bone loss. Ann. Rheum. Dis. 75 (2016), 721–729.
-
(2016)
Ann. Rheum. Dis.
, vol.75
, pp. 721-729
-
-
Krishnamurthy, A.1
Joshua, V.2
Haj Hensvold, A.3
Jin, T.4
Sun, M.5
Vivar, N.6
Ytterberg, A.J.7
Engström, M.8
Fernandes-Cerqueira, C.9
Amara, K.10
-
55
-
-
84904545875
-
Secukinumab in plaque psoriasis–results of two phase 3 trials
-
Langley, R.G., Elewski, B.E., Lebwohl, M., Reich, K., Griffiths, C.E., Papp, K., Puig, L., Nakagawa, H., Spelman, L., Sigurgeirsson, B., et al. ERASURE Study Group, FIXTURE Study Group. Secukinumab in plaque psoriasis–results of two phase 3 trials. N. Engl. J. Med. 371 (2014), 326–338.
-
(2014)
N. Engl. J. Med.
, vol.371
, pp. 326-338
-
-
Langley, R.G.1
Elewski, B.E.2
Lebwohl, M.3
Reich, K.4
Griffiths, C.E.5
Papp, K.6
Puig, L.7
Nakagawa, H.8
Spelman, L.9
Sigurgeirsson, B.10
-
56
-
-
84861060158
-
T-cell autoreactivity to citrullinated autoantigenic peptides in rheumatoid arthritis patients carrying HLA-DRB1 shared epitope alleles
-
Law, S.C., Street, S., Yu, C.H., Capini, C., Ramnoruth, S., Nel, H.J., van Gorp, E., Hyde, C., Lau, K., Pahau, H., et al. T-cell autoreactivity to citrullinated autoantigenic peptides in rheumatoid arthritis patients carrying HLA-DRB1 shared epitope alleles. Arthritis Res. Ther., 14, 2012, R118.
-
(2012)
Arthritis Res. Ther.
, vol.14
, pp. R118
-
-
Law, S.C.1
Street, S.2
Yu, C.H.3
Capini, C.4
Ramnoruth, S.5
Nel, H.J.6
van Gorp, E.7
Hyde, C.8
Lau, K.9
Pahau, H.10
-
57
-
-
84902593564
-
Tofacitinib versus methotrexate in rheumatoid arthritis
-
Lee, E.B., Fleischmann, R., Hall, S., Wilkinson, B., Bradley, J.D., Gruben, D., Koncz, T., Krishnaswami, S., Wallenstein, G.V., Zang, C., et al., ORAL Start Investigators. Tofacitinib versus methotrexate in rheumatoid arthritis. N. Engl. J. Med. 370 (2014), 2377–2386.
-
(2014)
N. Engl. J. Med.
, vol.370
, pp. 2377-2386
-
-
Lee, E.B.1
Fleischmann, R.2
Hall, S.3
Wilkinson, B.4
Bradley, J.D.5
Gruben, D.6
Koncz, T.7
Krishnaswami, S.8
Wallenstein, G.V.9
Zang, C.10
-
58
-
-
71549117557
-
Synovial fibroblasts spread rheumatoid arthritis to unaffected joints
-
Lefèvre, S., Knedla, A., Tennie, C., Kampmann, A., Wunrau, C., Dinser, R., Korb, A., Schnäker, E.M., Tarner, I.H., Robbins, P.D., et al. Synovial fibroblasts spread rheumatoid arthritis to unaffected joints. Nat. Med. 15 (2009), 1414–1420.
-
(2009)
Nat. Med.
, vol.15
, pp. 1414-1420
-
-
Lefèvre, S.1
Knedla, A.2
Tennie, C.3
Kampmann, A.4
Wunrau, C.5
Dinser, R.6
Korb, A.7
Schnäker, E.M.8
Tarner, I.H.9
Robbins, P.D.10
-
59
-
-
33144481274
-
Smoking is a risk factor for anti-CCP antibodies only in rheumatoid arthritis patients who carry HLA-DRB1 shared epitope alleles
-
Linn-Rasker, S.P., van der Helm-van Mil, A.H., van Gaalen, F.A., Kloppenburg, M., de Vries, R.R., le Cessie, S., Breedveld, F.C., Toes, R.E., Huizinga, T.W., Smoking is a risk factor for anti-CCP antibodies only in rheumatoid arthritis patients who carry HLA-DRB1 shared epitope alleles. Ann. Rheum. Dis. 65 (2006), 366–371.
-
(2006)
Ann. Rheum. Dis.
, vol.65
, pp. 366-371
-
-
Linn-Rasker, S.P.1
van der Helm-van Mil, A.H.2
van Gaalen, F.A.3
Kloppenburg, M.4
de Vries, R.R.5
le Cessie, S.6
Breedveld, F.C.7
Toes, R.E.8
Huizinga, T.W.9
-
60
-
-
84982702456
-
Role of the gut microbiome in modulating arthritis progression in mice
-
Liu, X., Zeng, B., Zhang, J., Li, W., Mou, F., Wang, H., Zou, Q., Zhong, B., Wu, L., Wei, H., Fang, Y., Role of the gut microbiome in modulating arthritis progression in mice. Sci. Rep., 6, 2016, 30594.
-
(2016)
Sci. Rep.
, vol.6
, pp. 30594
-
-
Liu, X.1
Zeng, B.2
Zhang, J.3
Li, W.4
Mou, F.5
Wang, H.6
Zou, Q.7
Zhong, B.8
Wu, L.9
Wei, H.10
Fang, Y.11
-
61
-
-
84933672236
-
The IL-23-IL-17 axis in inflammatory arthritis
-
Lubberts, E., The IL-23-IL-17 axis in inflammatory arthritis. Nat. Rev. Rheumatol. 11 (2015), 415–429.
-
(2015)
Nat. Rev. Rheumatol.
, vol.11
, pp. 415-429
-
-
Lubberts, E.1
-
62
-
-
66449118743
-
Gene-environment interaction between the DRB1 shared epitope and smoking in the risk of anti-citrullinated protein antibody-positive rheumatoid arthritis: all alleles are important
-
Lundström, E., Källberg, H., Alfredsson, L., Klareskog, L., Padyukov, L., Gene-environment interaction between the DRB1 shared epitope and smoking in the risk of anti-citrullinated protein antibody-positive rheumatoid arthritis: all alleles are important. Arthritis Rheum. 60 (2009), 1597–1603.
-
(2009)
Arthritis Rheum.
, vol.60
, pp. 1597-1603
-
-
Lundström, E.1
Källberg, H.2
Alfredsson, L.3
Klareskog, L.4
Padyukov, L.5
-
63
-
-
53149103590
-
Smoking increases peptidylarginine deiminase 2 enzyme expression in human lungs and increases citrullination in BAL cells
-
Makrygiannakis, D., Hermansson, M., Ulfgren, A.K., Nicholas, A.P., Zendman, A.J., Eklund, A., Grunewald, J., Skold, C.M., Klareskog, L., Catrina, A.I., Smoking increases peptidylarginine deiminase 2 enzyme expression in human lungs and increases citrullination in BAL cells. Ann. Rheum. Dis. 67 (2008), 1488–1492.
-
(2008)
Ann. Rheum. Dis.
, vol.67
, pp. 1488-1492
-
-
Makrygiannakis, D.1
Hermansson, M.2
Ulfgren, A.K.3
Nicholas, A.P.4
Zendman, A.J.5
Eklund, A.6
Grunewald, J.7
Skold, C.M.8
Klareskog, L.9
Catrina, A.I.10
-
64
-
-
0036230130
-
How antibodies to a ubiquitous cytoplasmic enzyme may provoke joint-specific autoimmune disease
-
Matsumoto, I., Maccioni, M., Lee, D.M., Maurice, M., Simmons, B., Brenner, M., Mathis, D., Benoist, C., How antibodies to a ubiquitous cytoplasmic enzyme may provoke joint-specific autoimmune disease. Nat. Immunol. 3 (2002), 360–365.
-
(2002)
Nat. Immunol.
, vol.3
, pp. 360-365
-
-
Matsumoto, I.1
Maccioni, M.2
Lee, D.M.3
Maurice, M.4
Simmons, B.5
Brenner, M.6
Mathis, D.7
Benoist, C.8
-
65
-
-
34249720998
-
Cytokines in the pathogenesis of rheumatoid arthritis
-
McInnes, I.B., Schett, G., Cytokines in the pathogenesis of rheumatoid arthritis. Nat. Rev. Immunol. 7 (2007), 429–442.
-
(2007)
Nat. Rev. Immunol.
, vol.7
, pp. 429-442
-
-
McInnes, I.B.1
Schett, G.2
-
66
-
-
84855172814
-
The pathogenesis of rheumatoid arthritis
-
McInnes, I.B., Schett, G., The pathogenesis of rheumatoid arthritis. N. Engl. J. Med. 365 (2011), 2205–2219.
-
(2011)
N. Engl. J. Med.
, vol.365
, pp. 2205-2219
-
-
McInnes, I.B.1
Schett, G.2
-
67
-
-
84942198180
-
Secukinumab, a human anti-interleukin-17A monoclonal antibody, in patients with psoriatic arthritis (FUTURE 2): a randomized, double-blind, placebo-controlled, phase 3 trial
-
McInnes, I.B., Mease, P.J., Kirkham, B., Kavanaugh, A., Ritchlin, C.T., Rahman, P., van der Heijde, D., Landewé, R., Conaghan, P.G., Gottlieb, A.B., et al., FUTURE 2 Study Group. Secukinumab, a human anti-interleukin-17A monoclonal antibody, in patients with psoriatic arthritis (FUTURE 2): a randomized, double-blind, placebo-controlled, phase 3 trial. Lancet 386 (2015), 1137–1146.
-
(2015)
Lancet
, vol.386
, pp. 1137-1146
-
-
McInnes, I.B.1
Mease, P.J.2
Kirkham, B.3
Kavanaugh, A.4
Ritchlin, C.T.5
Rahman, P.6
van der Heijde, D.7
Landewé, R.8
Conaghan, P.G.9
Gottlieb, A.B.10
-
68
-
-
84954197348
-
Cytokines in rheumatoid arthritis - shaping the immunological landscape
-
McInnes, I.B., Buckley, C.D., Isaacs, J.D., Cytokines in rheumatoid arthritis - shaping the immunological landscape. Nat. Rev. Rheumatol. 12 (2016), 63–68.
-
(2016)
Nat. Rev. Rheumatol.
, vol.12
, pp. 63-68
-
-
McInnes, I.B.1
Buckley, C.D.2
Isaacs, J.D.3
-
69
-
-
69249222895
-
Role for TNF in atherosclerosis? Lessons from autoimmune disease
-
McKellar, G.E., McCarey, D.W., Sattar, N., McInnes, I.B., Role for TNF in atherosclerosis? Lessons from autoimmune disease. Nat. Rev. Cardiol. 6 (2009), 410–417.
-
(2009)
Nat. Rev. Cardiol.
, vol.6
, pp. 410-417
-
-
McKellar, G.E.1
McCarey, D.W.2
Sattar, N.3
McInnes, I.B.4
-
70
-
-
84866934694
-
Targeting IL-17 and TH17 cells in chronic inflammation
-
Miossec, P., Kolls, J.K., Targeting IL-17 and TH17 cells in chronic inflammation. Nat. Rev. Drug Discov. 11 (2012), 763–776.
-
(2012)
Nat. Rev. Drug Discov.
, vol.11
, pp. 763-776
-
-
Miossec, P.1
Kolls, J.K.2
-
71
-
-
0029855587
-
Synovial fibroblasts of patients with rheumatoid arthritis attach to and invade normal human cartilage when engrafted into SCID mice
-
Müller-Ladner, U., Kriegsmann, J., Franklin, B.N., Matsumoto, S., Geiler, T., Gay, R.E., Gay, S., Synovial fibroblasts of patients with rheumatoid arthritis attach to and invade normal human cartilage when engrafted into SCID mice. Am. J. Pathol. 149 (1996), 1607–1615.
-
(1996)
Am. J. Pathol.
, vol.149
, pp. 1607-1615
-
-
Müller-Ladner, U.1
Kriegsmann, J.2
Franklin, B.N.3
Matsumoto, S.4
Geiler, T.5
Gay, R.E.6
Gay, S.7
-
72
-
-
77953627756
-
Carbamylation-dependent activation of T cells: a novel mechanism in the pathogenesis of autoimmune arthritis
-
Mydel, P., Wang, Z., Brisslert, M., Hellvard, A., Dahlberg, L.E., Hazen, S.L., Bokarewa, M., Carbamylation-dependent activation of T cells: a novel mechanism in the pathogenesis of autoimmune arthritis. J. Immunol. 184 (2010), 6882–6890.
-
(2010)
J. Immunol.
, vol.184
, pp. 6882-6890
-
-
Mydel, P.1
Wang, Z.2
Brisslert, M.3
Hellvard, A.4
Dahlberg, L.E.5
Hazen, S.L.6
Bokarewa, M.7
-
73
-
-
66049112958
-
MicroRNA-124a is a key regulator of proliferation and monocyte chemoattractant protein 1 secretion in fibroblast-like synoviocytes from patients with rheumatoid arthritis
-
Nakamachi, Y., Kawano, S., Takenokuchi, M., Nishimura, K., Sakai, Y., Chin, T., Saura, R., Kurosaka, M., Kumagai, S., MicroRNA-124a is a key regulator of proliferation and monocyte chemoattractant protein 1 secretion in fibroblast-like synoviocytes from patients with rheumatoid arthritis. Arthritis Rheum. 60 (2009), 1294–1304.
-
(2009)
Arthritis Rheum.
, vol.60
, pp. 1294-1304
-
-
Nakamachi, Y.1
Kawano, S.2
Takenokuchi, M.3
Nishimura, K.4
Sakai, Y.5
Chin, T.6
Saura, R.7
Kurosaka, M.8
Kumagai, S.9
-
74
-
-
84871050696
-
DNA methylome signature in rheumatoid arthritis
-
Nakano, K., Whitaker, J.W., Boyle, D.L., Wang, W., Firestein, G.S., DNA methylome signature in rheumatoid arthritis. Ann. Rheum. Dis. 72 (2013), 110–117.
-
(2013)
Ann. Rheum. Dis.
, vol.72
, pp. 110-117
-
-
Nakano, K.1
Whitaker, J.W.2
Boyle, D.L.3
Wang, W.4
Firestein, G.S.5
-
75
-
-
84872713887
-
Regulation of DNA methylation in rheumatoid arthritis synoviocytes
-
Nakano, K., Boyle, D.L., Firestein, G.S., Regulation of DNA methylation in rheumatoid arthritis synoviocytes. J. Immunol. 190 (2013), 1297–1303.
-
(2013)
J. Immunol.
, vol.190
, pp. 1297-1303
-
-
Nakano, K.1
Boyle, D.L.2
Firestein, G.S.3
-
76
-
-
84893721202
-
Efficacy of biological disease-modifying antirheumatic drugs: a systematic literature review informing the 2013 update of the EULAR recommendations for the management of rheumatoid arthritis
-
Nam, J.L., Ramiro, S., Gaujoux-Viala, C., Takase, K., Leon-Garcia, M., Emery, P., Gossec, L., Landewe, R., Smolen, J.S., Buch, M.H., Efficacy of biological disease-modifying antirheumatic drugs: a systematic literature review informing the 2013 update of the EULAR recommendations for the management of rheumatoid arthritis. Ann. Rheum. Dis. 73 (2014), 516–528.
-
(2014)
Ann. Rheum. Dis.
, vol.73
, pp. 516-528
-
-
Nam, J.L.1
Ramiro, S.2
Gaujoux-Viala, C.3
Takase, K.4
Leon-Garcia, M.5
Emery, P.6
Gossec, L.7
Landewe, R.8
Smolen, J.S.9
Buch, M.H.10
-
77
-
-
84894288992
-
Genetics of rheumatoid arthritis contributes to biology and drug discovery
-
Okada, Y., Wu, D., Trynka, G., Raj, T., Terao, C., Ikari, K., Kochi, Y., Ohmura, K., Suzuki, A., Yoshida, S., et al. RACI consortium, GARNET consortium. Genetics of rheumatoid arthritis contributes to biology and drug discovery. Nature 506 (2014), 376–381.
-
(2014)
Nature
, vol.506
, pp. 376-381
-
-
Okada, Y.1
Wu, D.2
Trynka, G.3
Raj, T.4
Terao, C.5
Ikari, K.6
Kochi, Y.7
Ohmura, K.8
Suzuki, A.9
Yoshida, S.10
-
78
-
-
0034467058
-
Activation of synovial fibroblasts in rheumatoid arthritis: lack of expression of the tumour suppressor PTEN at sites of invasive growth and destruction
-
Pap, T., Franz, J.K., Hummel, K.M., Jeisy, E., Gay, R., Gay, S., Activation of synovial fibroblasts in rheumatoid arthritis: lack of expression of the tumour suppressor PTEN at sites of invasive growth and destruction. Arthritis Res. 2 (2000), 59–64.
-
(2000)
Arthritis Res.
, vol.2
, pp. 59-64
-
-
Pap, T.1
Franz, J.K.2
Hummel, K.M.3
Jeisy, E.4
Gay, R.5
Gay, S.6
-
79
-
-
0037438376
-
IL-6 and matrix metalloproteinase-1 are regulated by the cyclin-dependent kinase inhibitor p21 in synovial fibroblasts
-
Perlman, H., Bradley, K., Liu, H., Cole, S., Shamiyeh, E., Smith, R.C., Walsh, K., Fiore, S., Koch, A.E., Firestein, G.S., et al. IL-6 and matrix metalloproteinase-1 are regulated by the cyclin-dependent kinase inhibitor p21 in synovial fibroblasts. J. Immunol. 170 (2003), 838–845.
-
(2003)
J. Immunol.
, vol.170
, pp. 838-845
-
-
Perlman, H.1
Bradley, K.2
Liu, H.3
Cole, S.4
Shamiyeh, E.5
Smith, R.C.6
Walsh, K.7
Fiore, S.8
Koch, A.E.9
Firestein, G.S.10
-
80
-
-
84903376485
-
Ectopic lymphoid-like structures in infection, cancer and autoimmunity
-
Pitzalis, C., Jones, G.W., Bombardieri, M., Jones, S.A., Ectopic lymphoid-like structures in infection, cancer and autoimmunity. Nat. Rev. Immunol. 14 (2014), 447–462.
-
(2014)
Nat. Rev. Immunol.
, vol.14
, pp. 447-462
-
-
Pitzalis, C.1
Jones, G.W.2
Bombardieri, M.3
Jones, S.A.4
-
81
-
-
0026523224
-
Clonally related IgM rheumatoid factors undergo affinity maturation in the rheumatoid synovial tissue
-
Randen, I., Brown, D., Thompson, K.M., Hughes-Jones, N., Pascual, V., Victor, K., Capra, J.D., Førre, O., Natvig, J.B., Clonally related IgM rheumatoid factors undergo affinity maturation in the rheumatoid synovial tissue. J. Immunol. 148 (1992), 3296–3301.
-
(1992)
J. Immunol.
, vol.148
, pp. 3296-3301
-
-
Randen, I.1
Brown, D.2
Thompson, K.M.3
Hughes-Jones, N.4
Pascual, V.5
Victor, K.6
Capra, J.D.7
Førre, O.8
Natvig, J.B.9
-
82
-
-
84925858831
-
The role of PTPN22 risk variant in the development of autoimmunity: finding common ground between mouse and human
-
Rawlings, D.J., Dai, X., Buckner, J.H., The role of PTPN22 risk variant in the development of autoimmunity: finding common ground between mouse and human. J. Immunol. 194 (2015), 2977–2984.
-
(2015)
J. Immunol.
, vol.194
, pp. 2977-2984
-
-
Rawlings, D.J.1
Dai, X.2
Buckner, J.H.3
-
83
-
-
84862776511
-
Five amino acids in three HLA proteins explain most of the association between MHC and seropositive rheumatoid arthritis
-
Raychaudhuri, S., Sandor, C., Stahl, E.A., Freudenberg, J., Lee, H.S., Jia, X., Alfredsson, L., Padyukov, L., Klareskog, L., Worthington, J., et al. Five amino acids in three HLA proteins explain most of the association between MHC and seropositive rheumatoid arthritis. Nat. Genet. 44 (2012), 291–296.
-
(2012)
Nat. Genet.
, vol.44
, pp. 291-296
-
-
Raychaudhuri, S.1
Sandor, C.2
Stahl, E.A.3
Freudenberg, J.4
Lee, H.S.5
Jia, X.6
Alfredsson, L.7
Padyukov, L.8
Klareskog, L.9
Worthington, J.10
-
84
-
-
21644479222
-
Early rheumatoid arthritis is characterized by a distinct and transient synovial fluid cytokine profile of T cell and stromal cell origin
-
Raza, K., Falciani, F., Curnow, S.J., Ross, E.J., Lee, C.Y., Akbar, A.N., Lord, J.M., Gordon, C., Buckley, C.D., Salmon, M., Early rheumatoid arthritis is characterized by a distinct and transient synovial fluid cytokine profile of T cell and stromal cell origin. Arthritis Res. Ther. 7 (2005), R784–R795.
-
(2005)
Arthritis Res. Ther.
, vol.7
, pp. R784-R795
-
-
Raza, K.1
Falciani, F.2
Curnow, S.J.3
Ross, E.J.4
Lee, C.Y.5
Akbar, A.N.6
Lord, J.M.7
Gordon, C.8
Buckley, C.D.9
Salmon, M.10
-
85
-
-
84897020028
-
Structural changes and antibody enrichment in the lungs are early features of anti-citrullinated protein antibody-positive rheumatoid arthritis
-
Reynisdottir, G., Karimi, R., Joshua, V., Olsen, H., Hensvold, A.H., Harju, A., Engström, M., Grunewald, J., Nyren, S., Eklund, A., et al. Structural changes and antibody enrichment in the lungs are early features of anti-citrullinated protein antibody-positive rheumatoid arthritis. Arthritis Rheumatol. 66 (2014), 31–39.
-
(2014)
Arthritis Rheumatol.
, vol.66
, pp. 31-39
-
-
Reynisdottir, G.1
Karimi, R.2
Joshua, V.3
Olsen, H.4
Hensvold, A.H.5
Harju, A.6
Engström, M.7
Grunewald, J.8
Nyren, S.9
Eklund, A.10
-
86
-
-
84984982215
-
Signs of immune activation and local inflammation are present in the bronchial tissue of patients with untreated early rheumatoid arthritis
-
Reynisdottir, G., Olsen, H., Joshua, V., Engström, M., Forsslund, H., Karimi, R., Sköld, C.M., Nyren, S., Eklund, A., Grunewald, J., Catrina, A.I., Signs of immune activation and local inflammation are present in the bronchial tissue of patients with untreated early rheumatoid arthritis. Ann. Rheum. Dis. 75 (2016), 1722–1727.
-
(2016)
Ann. Rheum. Dis.
, vol.75
, pp. 1722-1727
-
-
Reynisdottir, G.1
Olsen, H.2
Joshua, V.3
Engström, M.4
Forsslund, H.5
Karimi, R.6
Sköld, C.M.7
Nyren, S.8
Eklund, A.9
Grunewald, J.10
Catrina, A.I.11
-
87
-
-
84883458926
-
Changes in lipid levels with inflammation and therapy in RA: a maturing paradigm
-
Robertson, J., Peters, M.J., McInnes, I.B., Sattar, N., Changes in lipid levels with inflammation and therapy in RA: a maturing paradigm. Nat. Rev. Rheumatol. 9 (2013), 513–523.
-
(2013)
Nat. Rev. Rheumatol.
, vol.9
, pp. 513-523
-
-
Robertson, J.1
Peters, M.J.2
McInnes, I.B.3
Sattar, N.4
-
88
-
-
85007325313
-
Altered innate lymphoid cells subsets in human lymph node biopsies during the at risk and earliest phase of rheumatoid arthritis
-
Rodríguez-Carrio, J., Hähnlein, J.S., Ramwadhdoebe, T.H., Semmelink, J.F., Choi, I.Y., van Lienden, K.P., Maas, M., Gerlag, D.M., Tak, P.P., Geijtenbeek, T.B., van Baarsen, L.G., Altered innate lymphoid cells subsets in human lymph node biopsies during the at risk and earliest phase of rheumatoid arthritis. Arthritis Rheumatol. 69 (2016), 70–76.
-
(2016)
Arthritis Rheumatol.
, vol.69
, pp. 70-76
-
-
Rodríguez-Carrio, J.1
Hähnlein, J.S.2
Ramwadhdoebe, T.H.3
Semmelink, J.F.4
Choi, I.Y.5
van Lienden, K.P.6
Maas, M.7
Gerlag, D.M.8
Tak, P.P.9
Geijtenbeek, T.B.10
van Baarsen, L.G.11
-
89
-
-
84918590946
-
Anti-citrullinated protein antibodies acquire a pro-inflammatory Fc glycosylation phenotype prior to the onset of rheumatoid arthritis
-
Rombouts, Y., Ewing, E., van de Stadt, L.A., Selman, M.H., Trouw, L.A., Deelder, A.M., Huizinga, T.W., Wuhrer, M., van Schaardenburg, D., Toes, R.E., Scherer, H.U., Anti-citrullinated protein antibodies acquire a pro-inflammatory Fc glycosylation phenotype prior to the onset of rheumatoid arthritis. Ann. Rheum. Dis. 74 (2015), 234–241.
-
(2015)
Ann. Rheum. Dis.
, vol.74
, pp. 234-241
-
-
Rombouts, Y.1
Ewing, E.2
van de Stadt, L.A.3
Selman, M.H.4
Trouw, L.A.5
Deelder, A.M.6
Huizinga, T.W.7
Wuhrer, M.8
van Schaardenburg, D.9
Toes, R.E.10
Scherer, H.U.11
-
90
-
-
84977598497
-
TCR repertoire sequencing identifies synovial Treg cell clonotypes in the bloodstream during active inflammation in human arthritis
-
Rossetti, M., Spreafico, R., Consolaro, A., Leong, J.Y., Chua, C., Massa, M., Saidin, S., Magni-Manzoni, S., Arkachaisri, T., Wallace, C.A., et al. TCR repertoire sequencing identifies synovial Treg cell clonotypes in the bloodstream during active inflammation in human arthritis. Ann. Rheum. Dis. 76 (2017), 435–441.
-
(2017)
Ann. Rheum. Dis.
, vol.76
, pp. 435-441
-
-
Rossetti, M.1
Spreafico, R.2
Consolaro, A.3
Leong, J.Y.4
Chua, C.5
Massa, M.6
Saidin, S.7
Magni-Manzoni, S.8
Arkachaisri, T.9
Wallace, C.A.10
-
91
-
-
84888116736
-
A molecular basis for the association of the HLA-DRB1 locus, citrullination, and rheumatoid arthritis
-
Scally, S.W., Petersen, J., Law, S.C., Dudek, N.L., Nel, H.J., Loh, K.L., Wijeyewickrema, L.C., Eckle, S.B., van Heemst, J., Pike, R.N., et al. A molecular basis for the association of the HLA-DRB1 locus, citrullination, and rheumatoid arthritis. J. Exp. Med. 210 (2013), 2569–2582.
-
(2013)
J. Exp. Med.
, vol.210
, pp. 2569-2582
-
-
Scally, S.W.1
Petersen, J.2
Law, S.C.3
Dudek, N.L.4
Nel, H.J.5
Loh, K.L.6
Wijeyewickrema, L.C.7
Eckle, S.B.8
van Heemst, J.9
Pike, R.N.10
-
92
-
-
84887323708
-
Expansion of intestinal Prevotella copri correlates with enhanced susceptibility to arthritis
-
Scher, J.U., Sczesnak, A., Longman, R.S., Segata, N., Ubeda, C., Bielski, C., Rostron, T., Cerundolo, V., Pamer, E.G., Abramson, S.B., et al. Expansion of intestinal Prevotella copri correlates with enhanced susceptibility to arthritis. eLife, 2, 2013, e01202.
-
(2013)
eLife
, vol.2
, pp. e01202
-
-
Scher, J.U.1
Sczesnak, A.2
Longman, R.S.3
Segata, N.4
Ubeda, C.5
Bielski, C.6
Rostron, T.7
Cerundolo, V.8
Pamer, E.G.9
Abramson, S.B.10
-
93
-
-
84889641417
-
Head-to-head comparison of subcutaneous abatacept versus adalimumab for rheumatoid arthritis: two-year efficacy and safety findings from AMPLE trial
-
Schiff, M., Weinblatt, M.E., Valente, R., van der Heijde, D., Citera, G., Elegbe, A., Maldonado, M., Fleischmann, R., Head-to-head comparison of subcutaneous abatacept versus adalimumab for rheumatoid arthritis: two-year efficacy and safety findings from AMPLE trial. Ann. Rheum. Dis. 73 (2014), 86–94.
-
(2014)
Ann. Rheum. Dis.
, vol.73
, pp. 86-94
-
-
Schiff, M.1
Weinblatt, M.E.2
Valente, R.3
van der Heijde, D.4
Citera, G.5
Elegbe, A.6
Maldonado, M.7
Fleischmann, R.8
-
94
-
-
80054806901
-
Autoantibodies recognizing carbamylated proteins are present in sera of patients with rheumatoid arthritis and predict joint damage
-
Shi, J., Knevel, R., Suwannalai, P., van der Linden, M.P., Janssen, G.M., van Veelen, P.A., Levarht, N.E., van der Helm-van Mil, A.H., Cerami, A., Huizinga, T.W., et al. Autoantibodies recognizing carbamylated proteins are present in sera of patients with rheumatoid arthritis and predict joint damage. Proc. Natl. Acad. Sci. USA 108 (2011), 17372–17377.
-
(2011)
Proc. Natl. Acad. Sci. USA
, vol.108
, pp. 17372-17377
-
-
Shi, J.1
Knevel, R.2
Suwannalai, P.3
van der Linden, M.P.4
Janssen, G.M.5
van Veelen, P.A.6
Levarht, N.E.7
van der Helm-van Mil, A.H.8
Cerami, A.9
Huizinga, T.W.10
-
95
-
-
84895463561
-
Anti-carbamylated protein (anti-CarP) antibodies precede the onset of rheumatoid arthritis
-
Shi, J., van de Stadt, L.A., Levarht, E.W., Huizinga, T.W., Hamann, D., van Schaardenburg, D., Toes, R.E., Trouw, L.A., Anti-carbamylated protein (anti-CarP) antibodies precede the onset of rheumatoid arthritis. Ann. Rheum. Dis. 73 (2014), 780–783.
-
(2014)
Ann. Rheum. Dis.
, vol.73
, pp. 780-783
-
-
Shi, J.1
van de Stadt, L.A.2
Levarht, E.W.3
Huizinga, T.W.4
Hamann, D.5
van Schaardenburg, D.6
Toes, R.E.7
Trouw, L.A.8
-
96
-
-
84929023302
-
Rheumatoid arthritis therapy reappraisal: strategies, opportunities and challenges
-
Smolen, J.S., Aletaha, D., Rheumatoid arthritis therapy reappraisal: strategies, opportunities and challenges. Nat. Rev. Rheumatol. 11 (2015), 276–289.
-
(2015)
Nat. Rev. Rheumatol.
, vol.11
, pp. 276-289
-
-
Smolen, J.S.1
Aletaha, D.2
-
97
-
-
84964773927
-
Rheumatoid arthritis
-
Smolen, J.S., Aletaha, D., McInnes, I.B., Rheumatoid arthritis. Lancet 388 (2016), 2023–2038.
-
(2016)
Lancet
, vol.388
, pp. 2023-2038
-
-
Smolen, J.S.1
Aletaha, D.2
McInnes, I.B.3
-
98
-
-
80053494012
-
∗0401-positive humanized mice and rheumatoid arthritis patients
-
∗0401-positive humanized mice and rheumatoid arthritis patients. Arthritis Rheum. 63 (2011), 2873–2883.
-
(2011)
Arthritis Rheum.
, vol.63
, pp. 2873-2883
-
-
Snir, O.1
Rieck, M.2
Gebe, J.A.3
Yue, B.B.4
Rawlings, C.A.5
Nepom, G.6
Malmström, V.7
Buckner, J.H.8
-
99
-
-
78650779270
-
Immune complexes containing citrullinated fibrinogen costimulate macrophages via Toll-like receptor 4 and Fcγ receptor
-
Sokolove, J., Zhao, X., Chandra, P.E., Robinson, W.H., Immune complexes containing citrullinated fibrinogen costimulate macrophages via Toll-like receptor 4 and Fcγ receptor. Arthritis Rheum. 63 (2011), 53–62.
-
(2011)
Arthritis Rheum.
, vol.63
, pp. 53-62
-
-
Sokolove, J.1
Zhao, X.2
Chandra, P.E.3
Robinson, W.H.4
-
100
-
-
79551655444
-
Altered expression of microRNA-203 in rheumatoid arthritis synovial fibroblasts and its role in fibroblast activation
-
Stanczyk, J., Ospelt, C., Karouzakis, E., Filer, A., Raza, K., Kolling, C., Gay, R., Buckley, C.D., Tak, P.P., Gay, S., Kyburz, D., Altered expression of microRNA-203 in rheumatoid arthritis synovial fibroblasts and its role in fibroblast activation. Arthritis Rheum. 63 (2011), 373–381.
-
(2011)
Arthritis Rheum.
, vol.63
, pp. 373-381
-
-
Stanczyk, J.1
Ospelt, C.2
Karouzakis, E.3
Filer, A.4
Raza, K.5
Kolling, C.6
Gay, R.7
Buckley, C.D.8
Tak, P.P.9
Gay, S.10
Kyburz, D.11
-
101
-
-
0042667153
-
Functional haplotypes of PADI4, encoding citrullinating enzyme peptidylarginine deiminase 4, are associated with rheumatoid arthritis
-
Suzuki, A., Yamada, R., Chang, X., Tokuhiro, S., Sawada, T., Suzuki, M., Nagasaki, M., Nakayama-Hamada, M., Kawaida, R., Ono, M., et al. Functional haplotypes of PADI4, encoding citrullinating enzyme peptidylarginine deiminase 4, are associated with rheumatoid arthritis. Nat. Genet. 34 (2003), 395–402.
-
(2003)
Nat. Genet.
, vol.34
, pp. 395-402
-
-
Suzuki, A.1
Yamada, R.2
Chang, X.3
Tokuhiro, S.4
Sawada, T.5
Suzuki, M.6
Nagasaki, M.7
Nakayama-Hamada, M.8
Kawaida, R.9
Ono, M.10
-
102
-
-
84992197087
-
Historical observations contributing insights on etiopathogenesis of rheumatoid arthritis and role of rheumatoid factor
-
Tan, E.M., Smolen, J.S., Historical observations contributing insights on etiopathogenesis of rheumatoid arthritis and role of rheumatoid factor. J. Exp. Med. 213 (2016), 1937–1950.
-
(2016)
J. Exp. Med.
, vol.213
, pp. 1937-1950
-
-
Tan, E.M.1
Smolen, J.S.2
-
103
-
-
34248595623
-
Presentation of arthritogenic peptide to antigen-specific T cells by fibroblast-like synoviocytes
-
Tran, C.N., Davis, M.J., Tesmer, L.A., Endres, J.L., Motyl, C.D., Smuda, C., Somers, E.C., Chung, K.C., Urquhart, A.G., Lundy, S.K., et al. Presentation of arthritogenic peptide to antigen-specific T cells by fibroblast-like synoviocytes. Arthritis Rheum. 56 (2007), 1497–1506.
-
(2007)
Arthritis Rheum.
, vol.56
, pp. 1497-1506
-
-
Tran, C.N.1
Davis, M.J.2
Tesmer, L.A.3
Endres, J.L.4
Motyl, C.D.5
Smuda, C.6
Somers, E.C.7
Chung, K.C.8
Urquhart, A.G.9
Lundy, S.K.10
-
104
-
-
84922021718
-
Cigarette smoking reduces DNA methylation levels at multiple genomic loci but the effect is partially reversible upon cessation
-
Tsaprouni, L.G., Yang, T.P., Bell, J., Dick, K.J., Kanoni, S., Nisbet, J., Viñuela, A., Grundberg, E., Nelson, C.P., Meduri, E., et al. Cigarette smoking reduces DNA methylation levels at multiple genomic loci but the effect is partially reversible upon cessation. Epigenetics 9 (2014), 1382–1396.
-
(2014)
Epigenetics
, vol.9
, pp. 1382-1396
-
-
Tsaprouni, L.G.1
Yang, T.P.2
Bell, J.3
Dick, K.J.4
Kanoni, S.5
Nisbet, J.6
Viñuela, A.7
Grundberg, E.8
Nelson, C.P.9
Meduri, E.10
-
105
-
-
84884765647
-
ACPA fine-specificity profiles in early rheumatoid arthritis patients do not correlate with clinical features at baseline or with disease progression
-
van Beers, J.J., Willemze, A., Jansen, J.J., Engbers, G.H., Salden, M., Raats, J., Drijfhout, J.W., van der Helm-van Mil, A.H., Toes, R.E., Pruijn, G.J., ACPA fine-specificity profiles in early rheumatoid arthritis patients do not correlate with clinical features at baseline or with disease progression. Arthritis Res. Ther., 15, 2013, R140.
-
(2013)
Arthritis Res. Ther.
, vol.15
, pp. R140
-
-
van Beers, J.J.1
Willemze, A.2
Jansen, J.J.3
Engbers, G.H.4
Salden, M.5
Raats, J.6
Drijfhout, J.W.7
van der Helm-van Mil, A.H.8
Toes, R.E.9
Pruijn, G.J.10
-
106
-
-
33646348123
-
The HLA-DRB1 shared epitope alleles are primarily a risk factor for anti-cyclic citrullinated peptide antibodies and are not an independent risk factor for development of rheumatoid arthritis
-
van der Helm-van Mil, A.H., Verpoort, K.N., Breedveld, F.C., Huizinga, T.W., Toes, R.E., de Vries, R.R., The HLA-DRB1 shared epitope alleles are primarily a risk factor for anti-cyclic citrullinated peptide antibodies and are not an independent risk factor for development of rheumatoid arthritis. Arthritis Rheum. 54 (2006), 1117–1121.
-
(2006)
Arthritis Rheum.
, vol.54
, pp. 1117-1121
-
-
van der Helm-van Mil, A.H.1
Verpoort, K.N.2
Breedveld, F.C.3
Huizinga, T.W.4
Toes, R.E.5
de Vries, R.R.6
-
107
-
-
84896962060
-
Cellular and humoral immunity in arthritis are profoundly influenced by the interaction between cigarette smoke effects and host HLA-DR and DQ genes
-
Vassallo, R., Luckey, D., Behrens, M., Madden, B., Luthra, H., David, C., Taneja, V., Cellular and humoral immunity in arthritis are profoundly influenced by the interaction between cigarette smoke effects and host HLA-DR and DQ genes. Clin. Immunol. 152 (2014), 25–35.
-
(2014)
Clin. Immunol.
, vol.152
, pp. 25-35
-
-
Vassallo, R.1
Luckey, D.2
Behrens, M.3
Madden, B.4
Luthra, H.5
David, C.6
Taneja, V.7
-
108
-
-
84880733694
-
The autoimmunity-associated gene PTPN22 potentiates toll-like receptor-driven, type 1 interferon-dependent immunity
-
Wang, Y., Shaked, I., Stanford, S.M., Zhou, W., Curtsinger, J.M., Mikulski, Z., Shaheen, Z.R., Cheng, G., Sawatzke, K., Campbell, A.M., et al. The autoimmunity-associated gene PTPN22 potentiates toll-like receptor-driven, type 1 interferon-dependent immunity. Immunity 39 (2013), 111–122.
-
(2013)
Immunity
, vol.39
, pp. 111-122
-
-
Wang, Y.1
Shaked, I.2
Stanford, S.M.3
Zhou, W.4
Curtsinger, J.M.5
Mikulski, Z.6
Shaheen, Z.R.7
Cheng, G.8
Sawatzke, K.9
Campbell, A.M.10
-
109
-
-
77955733490
-
Peptidylarginine deiminase from Porphyromonas gingivalis citrullinates human fibrinogen and α-enolase: implications for autoimmunity in rheumatoid arthritis
-
Wegner, N., Wait, R., Sroka, A., Eick, S., Nguyen, K.A., Lundberg, K., Kinloch, A., Culshaw, S., Potempa, J., Venables, P.J., Peptidylarginine deiminase from Porphyromonas gingivalis citrullinates human fibrinogen and α-enolase: implications for autoimmunity in rheumatoid arthritis. Arthritis Rheum. 62 (2010), 2662–2672.
-
(2010)
Arthritis Rheum.
, vol.62
, pp. 2662-2672
-
-
Wegner, N.1
Wait, R.2
Sroka, A.3
Eick, S.4
Nguyen, K.A.5
Lundberg, K.6
Kinloch, A.7
Culshaw, S.8
Potempa, J.9
Venables, P.J.10
-
110
-
-
0026447387
-
The influence of HLA-DRB1 genes on disease severity in rheumatoid arthritis
-
Weyand, C.M., Hicok, K.C., Conn, D.L., Goronzy, J.J., The influence of HLA-DRB1 genes on disease severity in rheumatoid arthritis. Ann. Intern. Med. 117 (1992), 801–806.
-
(1992)
Ann. Intern. Med.
, vol.117
, pp. 801-806
-
-
Weyand, C.M.1
Hicok, K.C.2
Conn, D.L.3
Goronzy, J.J.4
-
111
-
-
84930376747
-
Genetics of rheumatoid arthritis in Asia–present and future
-
Yamamoto, K., Okada, Y., Suzuki, A., Kochi, Y., Genetics of rheumatoid arthritis in Asia–present and future. Nat. Rev. Rheumatol. 11 (2015), 375–379.
-
(2015)
Nat. Rev. Rheumatol.
, vol.11
, pp. 375-379
-
-
Yamamoto, K.1
Okada, Y.2
Suzuki, A.3
Kochi, Y.4
-
112
-
-
84961841635
-
Restoring oxidant signaling suppresses proarthritogenic T cell effector functions in rheumatoid arthritis
-
Yang, Z., Shen, Y., Oishi, H., Matteson, E.L., Tian, L., Goronzy, J.J., Weyand, C.M., Restoring oxidant signaling suppresses proarthritogenic T cell effector functions in rheumatoid arthritis. Sci. Transl. Med., 8, 2016, 331ra38.
-
(2016)
Sci. Transl. Med.
, vol.8
, pp. 331ra38
-
-
Yang, Z.1
Shen, Y.2
Oishi, H.3
Matteson, E.L.4
Tian, L.5
Goronzy, J.J.6
Weyand, C.M.7
-
113
-
-
84938817346
-
The oral and gut microbiomes are perturbed in rheumatoid arthritis and partly normalized after treatment
-
Zhang, X., Zhang, D., Jia, H., Feng, Q., Wang, D., Liang, D., Wu, X., Li, J., Tang, L., Li, Y., et al. The oral and gut microbiomes are perturbed in rheumatoid arthritis and partly normalized after treatment. Nat. Med. 21 (2015), 895–905.
-
(2015)
Nat. Med.
, vol.21
, pp. 895-905
-
-
Zhang, X.1
Zhang, D.2
Jia, H.3
Feng, Q.4
Wang, D.5
Liang, D.6
Wu, X.7
Li, J.8
Tang, L.9
Li, Y.10
-
114
-
-
0028362620
-
Early synovitis–synoviocytes and mononuclear cells
-
Zvaifler, N.J., Boyle, D., Firestein, G.S., Early synovitis–synoviocytes and mononuclear cells. Semin. Arthritis Rheum. 23:6, Suppl 2 (1994), 11–16.
-
(1994)
Semin. Arthritis Rheum.
, vol.23
, Issue.6, Suppl 2
, pp. 11-16
-
-
Zvaifler, N.J.1
Boyle, D.2
Firestein, G.S.3
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