-
1
-
-
70449657126
-
Rheumatoid arthritis genetics: 2009 update
-
Plenge RM. Rheumatoid arthritis genetics: 2009 update. Curr Rheumatol Rep. 2009;11:351-6
-
(2009)
Curr Rheumatol Rep
, vol.11
, pp. 351-356
-
-
Plenge, R.M.1
-
2
-
-
78649733694
-
Prevention of autoimmune rheumatic disease: State of the art and future perspectives
-
Klareskog L, Gregersen PK, Huizinga TW. Prevention of autoimmune rheumatic disease: state of the art and future perspectives. Ann Rheum Dis. 2010;69:2062-6
-
(2010)
Ann Rheum Dis
, vol.69
, pp. 2062-2066
-
-
Klareskog, L.1
Gregersen, P.K.2
Huizinga, T.W.3
-
3
-
-
84871778727
-
Duality of fibroblast-like synoviocytes in RA: Passive responders and imprinted aggressors
-
Bottini N, Firestein GS. Duality of fibroblast-like synoviocytes in RA: passive responders and imprinted aggressors. Nat Rev Rheumatol. 2013;9:24-33
-
(2013)
Nat Rev Rheumatol
, vol.9
, pp. 24-33
-
-
Bottini, N.1
Firestein, G.S.2
-
4
-
-
84877602531
-
The ascent of acetylation in the epigenetics of rheumatoid arthritis
-
Grabiec AM, Reedquist KA. The ascent of acetylation in the epigenetics of rheumatoid arthritis. Nat Rev Rheumatol. 2013;9: 311-8
-
(2013)
Nat Rev Rheumatol
, vol.9
, pp. 311-318
-
-
Grabiec, A.M.1
Reedquist, K.A.2
-
5
-
-
84875129831
-
DNA methylation dynamics in health and disease
-
Bergman Y, Cedar H. DNA methylation dynamics in health and disease. Nat Struct Mol Biol. 2013;20:274-81
-
(2013)
Nat Struct Mol Biol
, vol.20
, pp. 274-281
-
-
Bergman, Y.1
Cedar, H.2
-
6
-
-
0025666735
-
Evidence for impaired T cell DNA methylation in systemic lupus erythematosus and rheumatoid arthritis
-
Richardson B, Scheinbart L, Strahler J, Gross L, Hanash S, Johnson M. Evidence for impaired T cell DNA methylation in systemic lupus erythematosus and rheumatoid arthritis. Arthritis Rheum. 1990;33:1665-73
-
(1990)
Arthritis Rheum
, vol.33
, pp. 1665-1673
-
-
Richardson, B.1
Scheinbart, L.2
Strahler, J.3
Gross, L.4
Hanash, S.5
Johnson, M.6
-
7
-
-
0025736912
-
5- Methylcytosine content of DNA in blood, synovial mononuclear cells and synovial tissue from patients affected by autoimmunerheumatic diseases
-
Corvetta A, Della Bitta R, Luchetti MM, Pomponio G. 5- Methylcytosine content of DNA in blood, synovial mononuclear cells and synovial tissue from patients affected by autoimmunerheumatic diseases. J Chromatogr. 1991;566:481-91
-
(1991)
J Chromatogr
, vol.566
, pp. 481-491
-
-
Corvetta, A.1
Della Bitta, R.2
Luchetti, M.M.3
Pomponio, G.4
-
8
-
-
0030205396
-
DNA hypomethylation in inflammatory arthritis: Reversal with methotrexate
-
Kim YI, Logan JW, Mason JB, Roubenoff R. DNA hypomethylation in inflammatory arthritis: reversal withmethotrexate. J Lab ClinMed.1996;128:165-72 (Pubitemid 27506445)
-
(1996)
Journal of Laboratory and Clinical Medicine
, vol.128
, Issue.2
, pp. 165-172
-
-
Kim, Y.-I.1
Logan, J.W.2
Mason, J.B.3
Roubenoff, R.4
-
9
-
-
78751703609
-
Global DNA methylation, DNMT1, andMBD2 in patients with rheumatoid arthritis
-
Liu CC, Fang TJ, Ou TT,Wu CC, Li RN, Lin YC, et al. Global DNA methylation, DNMT1, andMBD2 in patients with rheumatoid arthritis. Immunol Lett. 2011;135:96-9
-
(2011)
Immunol Lett
, vol.135
, pp. 96-99
-
-
Liu, C.C.1
Fang, T.J.2
Ou, T.T.3
Wu, C.C.4
Li, R.N.5
Lin, Y.C.6
-
10
-
-
49449106856
-
Methylation status of a single CpG site in the IL6 promoter is related to IL6 messenger RNA levels and rheumatoid arthritis
-
Nile CJ, Read RC, AkilM, Duff GW,Wilson AG.Methylation status of a single CpG site in the IL6 promoter is related to IL6 messenger RNA levels and rheumatoid arthritis. Arthritis Rheum. 2008;58: 2686-93
-
(2008)
Arthritis Rheum
, vol.58
, pp. 2686-2693
-
-
Nile, C.J.1
Read, R.C.2
Akil, M.3
Duff, G.W.4
Wilson, A.G.5
-
11
-
-
84863685954
-
Interleukin-6 gene promoter methylation in rheumatoid arthritis and chronic periodontitis
-
Ishida K, Kobayashi T, Ito S, Komatsu Y, Yokoyama T, Okada M, et al. Interleukin-6 gene promoter methylation in rheumatoid arthritis and chronic periodontitis. J Periodontol. 2012;83:917-25
-
(2012)
J Periodontol
, vol.83
, pp. 917-925
-
-
Ishida, K.1
Kobayashi, T.2
Ito, S.3
Komatsu, Y.4
Yokoyama, T.5
Okada, M.6
-
12
-
-
84864799962
-
CD40L demethylation in CD4(+) Tcells from women with rheumatoid arthritis
-
Liao J, Liang G, Xie S, Zhao H, Zuo X, Li F, et al. CD40L demethylation in CD4(+) Tcells from women with rheumatoid arthritis. Clin Immunol. 2012;145:13-8
-
(2012)
Clin Immunol
, vol.145
, pp. 13-18
-
-
Liao, J.1
Liang, G.2
Xie, S.3
Zhao, H.4
Zuo, X.5
Li, F.6
-
13
-
-
75649151209
-
Changes in the pattern of DNA methylation associate with twin discordance in systemic lupus erythematosus
-
Javierre BM, Fernandez AF, Richter J, Al-Shahrour F, Martin-Subero JI, Rodriguez- Ubreva J, et al. Changes in the pattern of DNA methylation associate with twin discordance in systemic lupus erythematosus. Genome Res. 2010;20:170-9
-
(2010)
Genome Res
, vol.20
, pp. 170-179
-
-
Javierre, B.M.1
Fernandez, A.F.2
Richter, J.3
Al-Shahrour, F.4
Martin-Subero, J.I.5
Rodriguez- Ubreva, J.6
-
14
-
-
84873576566
-
Epigenome-wide association data implicate DNA methylation as an intermediary of genetic risk in rheumatoid arthritis
-
The first integrated genome wide analysis of DNA methylation and singlenucleotide polymorphisms (SNPs). It identifies alterations of DNA methylation as responsible for the associations between SNPs in the MHC region and rheumatoid arthritis
-
Liu Y, Aryee MJ, Padyukov L, Fallin MD, Hesselberg E, Runarsson A, et al. Epigenome-wide association data implicate DNA methylation as an intermediary of genetic risk in rheumatoid arthritis. Nat Biotechnol. 2013;31:142-7. The first integrated genome wide analysis of DNA methylation and singlenucleotide polymorphisms (SNPs). It identifies alterations of DNA methylation as responsible for the associations between SNPs in the MHC region and rheumatoid arthritis
-
(2013)
Nat Biotechnol
, vol.31
, pp. 142-147
-
-
Liu, Y.1
Aryee, M.J.2
Padyukov, L.3
Fallin, M.D.4
Hesselberg, E.5
Runarsson, A.6
-
15
-
-
0034541591
-
Retrotransposable L1 elements expressed in rheumatoid arthritis synovial tissue: Association with genomic DNA hypomethylation and influence on gene expression
-
DOI 10.1002/1529-0131 (200012) 43:12<2634::AID-ANR3>3.0.CO;2-1
-
NeidhartM, Rethage J, Kuchen S, Kunzler P, Crowl RM, Billingham ME, et al. Retrotransposable L1 elements expressed in rheumatoid arthritis synovial tissue: association with genomic DNA hypomethylation and influence on gene expression. Arthritis Rheum. 2000;43: 2634-47 (Pubitemid 32001729)
-
(2000)
Arthritis and Rheumatism
, vol.43
, Issue.12
, pp. 2634-2647
-
-
Neidhart, M.1
Rethage, J.2
Kuchen, S.3
Knzler, P.4
Crowl, R.M.5
Billingham, M.E.6
Gay, R.E.7
Gay, S.8
-
16
-
-
0442326220
-
The L1 retroelement-related p40 protein induces p38δ MAP kinase
-
DOI 10.1080/08916930310001637977
-
Kuchen S, Seemayer CA, Rethage J, von Knoch R, Kuenzler P, Beat AM, et al. The L1 retroelement-related p40 protein induces p38delta MAP kinase. Autoimmunity. 2004;37:57-65 (Pubitemid 38185911)
-
(2004)
Autoimmunity
, vol.37
, Issue.1
, pp. 57-65
-
-
Kuchen, S.1
Seemayer, C.A.2
Rethage, J.3
Von Knoch, R.4
Kuenzler, P.5
Michel, B.A.6
Gay, R.E.7
Gay, S.8
Neidhart, M.9
-
17
-
-
73249146755
-
DNA hypomethylation in rheumatoid arthritis synovial fibroblasts
-
Karouzakis E, Gay RE, Michel BA, Gay S, Neidhart M. DNA hypomethylation in rheumatoid arthritis synovial fibroblasts. Arthritis Rheum. 2009;60:3613-22
-
(2009)
Arthritis Rheum
, vol.60
, pp. 3613-3622
-
-
Karouzakis, E.1
Gay, R.E.2
Michel, B.A.3
Gay, S.4
Neidhart, M.5
-
18
-
-
84872713887
-
Regulation of DNA methylation in rheumatoid arthritis synoviocytes
-
Nakano K, Boyle DL, Firestein GS. Regulation of DNA methylation in rheumatoid arthritis synoviocytes. J Immunol. 2013;190:1297-303
-
(2013)
J Immunol
, vol.190
, pp. 1297-1303
-
-
Nakano, K.1
Boyle, D.L.2
Firestein, G.S.3
-
19
-
-
82555192432
-
DNA methylation regulates the expression of CXCL12 in rheumatoid arthritis synovial fibroblasts
-
Karouzakis E, Rengel Y, Jungel A, Kolling C, Gay RE, Michel BA, et al. DNA methylation regulates the expression of CXCL12 in rheumatoid arthritis synovial fibroblasts. Genes Immunol. 2011;12: 643-52
-
(2011)
Genes Immunol
, vol.12
, pp. 643-652
-
-
Karouzakis, E.1
Rengel, Y.2
Jungel, A.3
Kolling, C.4
Gay, R.E.5
Michel, B.A.6
-
20
-
-
33644890154
-
Hypermethylated promoter region of DR3, the death receptor 3 gene, in rheumatoid arthritis synovial cells
-
Takami N, Osawa K, Miura Y, Komai K, Taniguchi M, Shiraishi M, et al. Hypermethylated promoter region of DR3, the death receptor 3 gene, in rheumatoid arthritis synovial cells. Arthritis Rheum. 2006;54:779-87
-
(2006)
Arthritis Rheum
, vol.54
, pp. 779-787
-
-
Takami, N.1
Osawa, K.2
Miura, Y.3
Komai, K.4
Taniguchi, M.5
Shiraishi, M.6
-
21
-
-
0034646408
-
Expression and function of wingless and frizzled homologs in rheumatoid arthritis
-
DOI 10.1073/pnas.050574297
-
Sen M, Lauterbach K, El-Gabalawy H, Firestein GS, CorrM, Carson DA. Expression and function of wingless and frizzled homologs in rheumatoid arthritis. Proc Natl Acad Sci U S A. 2000;97:2791-6 (Pubitemid 30159250)
-
(2000)
Proceedings of the National Academy of Sciences of the United States of America
, vol.97
, Issue.6
, pp. 2791-2796
-
-
Sen, M.1
Lauterbach, K.2
El-Gabalawy, H.3
Firestein, G.S.4
Corr, M.5
Carson, D.A.6
-
22
-
-
84871525988
-
MeCP2modulates the canonicalWnt pathway activation by targeting SFRP4 in rheumatoid arthritis fibroblast- like synoviocytes in rats
-
Miao CG, Huang C, Huang Y, Yang YY, He X, Zhang L, et al. MeCP2modulates the canonicalWnt pathway activation by targeting SFRP4 in rheumatoid arthritis fibroblast- like synoviocytes in rats. Cell Signal. 2013;25:598-608
-
(2013)
Cell Signal
, vol.25
, pp. 598-608
-
-
Miao, C.G.1
Huang, C.2
Huang, Y.3
Yang, Y.Y.4
He, X.5
Zhang, L.6
-
23
-
-
84871050696
-
DNA methylome signature in rheumatoid arthritis
-
The first genome-wide DNA methylation analysis in RA FLS. It identifies signature alterations of DNA methylome in RA FLS in key pathways
-
Nakano K,Whitaker JW, Boyle DL,WangW, Firestein GS. DNA methylome signature in rheumatoid arthritis. Ann Rheum Dis. 2013;72:110-7. The first genome-wide DNA methylation analysis in RA FLS. It identifies signature alterations of DNA methylome in RA FLS in key pathways
-
(2013)
Ann Rheum Dis.
, vol.72
, pp. 110-117
-
-
Nakano, K.1
Whitaker, J.W.2
Boyle, D.L.3
Wang, W.4
Firestein, G.S.5
-
24
-
-
84876799113
-
An imprinted rheumatoid arthritis methylome signature reflects pathogenic phenotype
-
Whitaker JW, Shoemaker R, Boyle DL, Hillman J, Anderson D, Wang W, et al. An imprinted rheumatoid arthritis methylome signature reflects pathogenic phenotype. Genome Med. 2013;5:40
-
(2013)
Genome Med
, vol.5
, pp. 40
-
-
Whitaker, J.W.1
Shoemaker, R.2
Boyle, D.L.3
Hillman, J.4
Anderson, D.5
Wang, W.6
-
25
-
-
84875943253
-
Identification of novelmarkers in rheumatoid arthritis through integrated analysis of DNA methylation and microRNA expression
-
de la Rica L, Urquiza JM, Gomez-Cabrero D, Islam AB, Lopez- Bigas N, Tegner J, et al. Identification of novelmarkers in rheumatoid arthritis through integrated analysis of DNA methylation and microRNA expression. J Autoimmun. 2013;41:6-16
-
(2013)
J Autoimmun
, vol.41
, pp. 6-16
-
-
De La Rica, L.1
Urquiza, J.M.2
Gomez-Cabrero, D.3
Islam, A.B.4
Lopez- Bigas, N.5
Tegner, J.6
-
26
-
-
84861829515
-
Increased recycling of polyamines is associated with global DNA hypomethylation in rheumatoid arthritis synovial fibroblasts
-
One of the few models explaining what causes alterations of DNA methylation in RA FLS
-
Karouzakis E, Gay RE, Gay S, Neidhart M. Increased recycling of polyamines is associated with global DNA hypomethylation in rheumatoid arthritis synovial fibroblasts. Arthritis Rheum. 2012;64:1809-One of the few models explaining what causes alterations of DNA methylation in RA FLS
-
(2012)
Arthritis Rheum.
, vol.64
, pp. 1809-1817
-
-
Karouzakis, E.1
Gay, R.E.2
Gay, S.3
Neidhart, M.4
-
27
-
-
84875986482
-
CAMP signalling inhibits p53 acetylation and apoptosis via HDAC and SIRT deacetylases
-
Kloster MM, Naderi EH, Haaland I, Gjertsen BT, Blomhoff HK, Naderi S. cAMP signalling inhibits p53 acetylation and apoptosis via HDAC and SIRT deacetylases. Int J Oncol. 2013;42:1815-21
-
(2013)
Int J Oncol
, vol.42
, pp. 1815-1821
-
-
Kloster, M.M.1
Naderi, E.H.2
Haaland, I.3
Gjertsen, B.T.4
Blomhoff, H.K.5
Naderi, S.6
-
28
-
-
78049240315
-
Histone acetyltransferase mediated regulation of FOXP3 acetylation and Treg function
-
Xiao Y, Li B, Zhou Z, Hancock WW, Zhang H, Greene MI. Histone acetyltransferase mediated regulation of FOXP3 acetylation and Treg function. Curr Opin Immunol. 2010;22:583-91
-
(2010)
Curr Opin Immunol
, vol.22
, pp. 583-591
-
-
Xiao, Y.1
Li, B.2
Zhou, Z.3
Hancock, W.W.4
Zhang, H.5
Greene, M.I.6
-
29
-
-
84859492923
-
HDAC inhibitor therapy in autoimmunity and transplantation
-
Hancock WW, Akimova T, Beier UH, Liu Y, Wang L. HDAC inhibitor therapy in autoimmunity and transplantation. Ann Rheum Dis. 2012;71 Suppl 2:i46-54
-
(2012)
Ann Rheum Dis
, vol.71
, Issue.SUPPL. 2
-
-
Hancock, W.W.1
Akimova, T.2
Beier, U.H.3
Liu, Y.4
Wang, L.5
-
30
-
-
77951925741
-
Histone deacetylase inhibitors suppress inflammatory activation of rheumatoid arthritis patient synovial macrophages and tissue
-
Grabiec AM, Krausz S, de JagerW, Burakowski T, Groot D, Sanders ME, et al. Histone deacetylase inhibitors suppress inflammatory activation of rheumatoid arthritis patient synovial macrophages and tissue. J Immunol. 2010;184:2718-28
-
(2010)
J Immunol
, vol.184
, pp. 2718-2728
-
-
Grabiec, A.M.1
Krausz, S.2
De Jager, W.3
Burakowski, T.4
Groot, D.5
Sanders, M.E.6
-
31
-
-
84857233842
-
Histone deacetylase inhibitors suppress rheumatoid arthritis fibroblast-like synoviocyte and macrophage IL-6 production by accelerating mRNA decay
-
Demonstrates the effect of HDACi on key target cytokine for therapy of RA
-
Grabiec AM, Korchynskyi O, Tak PP, Reedquist KA. Histone deacetylase inhibitors suppress rheumatoid arthritis fibroblast-like synoviocyte and macrophage IL-6 production by accelerating mRNA decay. Ann Rheum Dis. 2012;71:424-31. Demonstrates the effect of HDACi on key target cytokine for therapy of RA
-
(2012)
Ann Rheum Dis.
, vol.71
, pp. 424-431
-
-
Grabiec, A.M.1
Korchynskyi, O.2
Tak, P.P.3
Reedquist, K.A.4
-
32
-
-
84863395477
-
Histone deacetylases are dysregulated in rheumatoid arthritis and a novel histone deacetylase 3-selective inhibitor reduces interleukin-6 production by peripheral blood mononuclear cells from rheumatoid arthritis patients
-
Gillespie J, Savic S,Wong C, Hempshall A, InmanM, Emery P, et al. Histone deacetylases are dysregulated in rheumatoid arthritis and a novel histone deacetylase 3-selective inhibitor reduces interleukin-6 production by peripheral blood mononuclear cells from rheumatoid arthritis patients. Arthritis Rheum. 2012;64:418-22
-
(2012)
Arthritis Rheum
, vol.64
, pp. 418-422
-
-
Gillespie, J.1
Savic, S.2
Wong, C.3
Hempshall, A.4
Inman, M.5
Emery, P.6
-
33
-
-
80052453175
-
SIRT1 overexpression in the rheumatoid arthritis synovium contributes to proinflammatory cytokine production and apoptosis resistance
-
Niederer F, Ospelt C, Brentano F, HottigerMO, Gay RE, Gay S, et al. SIRT1 overexpression in the rheumatoid arthritis synovium contributes to proinflammatory cytokine production and apoptosis resistance. Ann Rheum Dis. 2011;70:1866-73
-
(2011)
Ann Rheum Dis
, vol.70
, pp. 1866-1873
-
-
Niederer, F.1
Ospelt, C.2
Brentano, F.3
Hottiger, M.O.4
Gay, R.E.5
Gay, S.6
-
34
-
-
70349385423
-
Deacetylase inhibition increases regulatory T cell function and decreases incidence and severity of collagen-induced arthritis
-
Saouaf SJ, Li B, Zhang G, Shen Y, Furuuchi N, HancockWW, et al. Deacetylase inhibition increases regulatory T cell function and decreases incidence and severity of collagen-induced arthritis. Exp Mol Pathol. 2009;87:99-104
-
(2009)
Exp Mol Pathol
, vol.87
, pp. 99-104
-
-
Saouaf, S.J.1
Li, B.2
Zhang, G.3
Shen, Y.4
Furuuchi, N.5
Hancock, W.W.6
-
35
-
-
34247227700
-
Histone deacetylase/acetylase activity in total synovial tissue derived from rheumatoid arthritis and osteoarthritis patients
-
DOI 10.1002/art.22512
-
Huber LC, Brock M, Hemmatazad H, Giger OT, Moritz F, Trenkmann M, et al. Histone deacetylase/acetylase activity in total synovial tissue derived from rheumatoid arthritis and osteoarthritis patients. Arthritis Rheum. 2007;56:1087-93 (Pubitemid 46608633)
-
(2007)
Arthritis and Rheumatism
, vol.56
, Issue.4
, pp. 1087-1093
-
-
Huber, L.C.1
Brock, M.2
Hemmatazad, H.3
Giger, O.T.4
Moritz, F.5
Trenkmann, M.6
Distler, J.H.W.7
Gay, R.E.8
Kolling, C.9
Moch, H.10
Michel, B.A.11
Gay, S.12
Distler, O.13
Jungel, A.14
-
36
-
-
77953288864
-
Epigenetics and rheumatoid arthritis: The role of SENP1 in the regulation of MMP-1 expression
-
Maciejewska-Rodrigues H, Karouzakis E, Strietholt S, Hemmatazad H, Neidhart M, Ospelt C, et al. Epigenetics and rheumatoid arthritis: the role of SENP1 in the regulation of MMP-1 expression. J Autoimmun. 2010;35:15-22
-
(2010)
J Autoimmun
, vol.35
, pp. 15-22
-
-
Maciejewska-Rodrigues, H.1
Karouzakis, E.2
Strietholt, S.3
Hemmatazad, H.4
Neidhart, M.5
Ospelt, C.6
-
37
-
-
68849105560
-
Expression and function of histone deacetylases in rheumatoid arthritis synovial fibroblasts
-
HoriuchiM,Morinobu A, Chin T, Sakai Y, KurosakaM, Kumagai S. Expression and function of histone deacetylases in rheumatoid arthritis synovial fibroblasts. J Rheumatol. 2009;36:1580-9
-
(2009)
J Rheumatol
, vol.36
, pp. 1580-1589
-
-
Horiuchi, M.1
Morinobu, A.2
Chin, T.3
Sakai, Y.4
Kurosaka, M.5
Kumagai, S.6
-
38
-
-
77954286123
-
Increased activity and expression of histone deacetylase 1 in relation to tumor necrosis factor- alpha in synovial tissue of rheumatoidarthritis
-
Kawabata T, Nishida K, Takasugi K, Ogawa H, Sada K, Kadota Y, et al. Increased activity and expression of histone deacetylase 1 in relation to tumor necrosis factor- alpha in synovial tissue of rheumatoidarthritis. Arthritis Res Ther. 2010;12:R133
-
(2010)
Arthritis Res Ther
, vol.12
-
-
Kawabata, T.1
Nishida, K.2
Takasugi, K.3
Ogawa, H.4
Sada, K.5
Kadota, Y.6
-
39
-
-
84880493174
-
The role of histone deacetylases in rheumatoid arthritis fibroblast-like synoviocytes
-
Hawtree S,MuthanaM,Wilson AG. The role of histone deacetylases in rheumatoid arthritis fibroblast-like synoviocytes. Biochem Soc Trans. 2013;41:783-8
-
(2013)
Biochem Soc Trans.
, vol.41
, pp. 783-788
-
-
Hawtree, S.1
Muthana, M.2
Wilson, A.G.3
-
40
-
-
79959788025
-
Expression and function of EZH2 in synovial fibroblasts: Epigenetic repression of the Wnt inhibitor SFRP1 in rheumatoid arthritis
-
Trenkmann M, Brock M, Gay RE, Kolling C, Speich R, Michel BA, et al. Expression and function of EZH2 in synovial fibroblasts: epigenetic repression of the Wnt inhibitor SFRP1 in rheumatoid arthritis. Ann Rheum Dis. 2011;70:1482-8
-
(2011)
Ann Rheum Dis
, vol.70
, pp. 1482-1488
-
-
Trenkmann, M.1
Brock, M.2
Gay, R.E.3
Kolling, C.4
Speich, R.5
Michel, B.A.6
-
41
-
-
43049183658
-
Antiarthritic effects of combined treatment with histone deacetylase inhibitorand low-intensity ultrasound in the presence of microbubbles in human rheumatoid synovial cells
-
Nakamura C, Matsushita I, Kosaka E, Kondo T, Kimura T. Antiarthritic effects of combined treatment with histone deacetylase inhibitorand low-intensity ultrasound in the presence of microbubbles in human rheumatoid synovial cells. Rheumatology (Oxford). 2008;47:418-24
-
(2008)
Rheumatology (Oxford)
, vol.47
, pp. 418-424
-
-
Nakamura, C.1
Matsushita, I.2
Kosaka, E.3
Kondo, T.4
Kimura, T.5
-
42
-
-
77954752923
-
Histone deacetylase inhibitors MS-275 and SAHA induced growth arrest and suppressed lipopolysaccharide-stimulated NF-kappaB p65 nuclear accumulation in human rheumatoid arthritis synovial fibroblastic E11 cells
-
Choo QY, Ho PC, Tanaka Y, Lin HS. Histone deacetylase inhibitors MS-275 and SAHA induced growth arrest and suppressed lipopolysaccharide-stimulated NF-kappaB p65 nuclear accumulation in human rheumatoid arthritis synovial fibroblastic E11 cells. Rheumatology (Oxford). 2010;49:1447-60
-
(2010)
Rheumatology (Oxford)
, vol.49
, pp. 1447-1460
-
-
Choo, Q.Y.1
Ho, P.C.2
Tanaka, Y.3
Lin, H.S.4
-
43
-
-
0346873023
-
A therapeutic strategy uses histone deacetylase inhibitors to modulate the expression of genes involved in the pathogenesis of rheumatoid arthritis
-
Chung YL, Lee MY, Wang AJ, Yao LF. A therapeutic strategy uses histone deacetylase inhibitors to modulate the expression of genes involved in the pathogenesis of rheumatoid arthritis. Mol Ther. 2003;8:707-17
-
(2003)
Mol Ther
, vol.8
, pp. 707-717
-
-
Chung, Y.L.1
Lee, M.Y.2
Wang, A.J.3
Yao, L.F.4
-
44
-
-
34047210698
-
Anti-rheumatic activities of histone deacetylase (HDAC) inhibitors in vivo in collagen-induced arthritis in rodents
-
DOI 10.1038/sj.bjp.0707165, PII 0707165
-
Lin HS, Hu CY, Chan HY, Liew YY, Huang HP, Lepescheux L, et al. Anti-rheumatic activities of histone deacetylase (HDAC) inhibitors in vivo in collagen-induced arthritis in rodents. Br J Pharmacol. 2007;150:862-72 (Pubitemid 46536628)
-
(2007)
British Journal of Pharmacology
, vol.150
, Issue.7
, pp. 862-872
-
-
Lin, H.-S.1
Hu, C.-Y.2
Chan, H.-Y.3
Liew, Y.-Y.4
Huang, H.-P.5
Lepescheux, L.6
Bastianelli, E.7
Baron, R.8
Rawadi, G.9
Clement-Lacroix, P.10
-
45
-
-
79957958931
-
Inhibition of HDAC activity by ITF2357 ameliorates joint inflammation and prevents cartilage and bone destruction in experimental arthritis
-
Preclinical validation of HDACi in models of RA
-
Joosten LA, Leoni F, Meghji S, Mascagni P. Inhibition of HDAC activity by ITF2357 ameliorates joint inflammation and prevents cartilage and bone destruction in experimental arthritis. Mol Med. 2011;17:391-6. Preclinical validation of HDACi in models of RA
-
(2011)
Mol Med.
, vol.17
, pp. 391-396
-
-
Joosten, L.A.1
Leoni, F.2
Meghji, S.3
Mascagni, P.4
-
46
-
-
79955552937
-
Safety and efficacy of an oral histone deacetylase inhibitor in systemic-onset juvenile idiopathic arthritis
-
The only published clinical trial of HDACi for human arthritis
-
Vojinovic J, Damjanov N, D'Urzo C, Furlan A, Susic G, Pasic S, et al. Safety and efficacy of an oral histone deacetylase inhibitor in systemic-onset juvenile idiopathic arthritis. Arthritis Rheum. 2011;63:1452-8. The only published clinical trial of HDACi for human arthritis
-
(2011)
Arthritis Rheum
, vol.63
, pp. 1452-1458
-
-
Vojinovic, J.1
Damjanov, N.2
D'Urzo, C.3
Furlan, A.4
Susic, G.5
Pasic, S.6
-
47
-
-
66049112958
-
MicroRNA-124a is a key regulator of proliferation and monocyte chemoattractant protein 1 secretion in fibroblast-like synoviocytes from patients with rheumatoid arthritis
-
Nakamachi Y, Kawano S, Takenokuchi M, Nishimura K, Sakai Y, Chin T, et al. MicroRNA-124a is a key regulator of proliferation and monocyte chemoattractant protein 1 secretion in fibroblast-like synoviocytes from patients with rheumatoid arthritis. Arthritis Rheum. 2009;60:1294-304
-
(2009)
Arthritis Rheum
, vol.60
, pp. 1294-1304
-
-
Nakamachi, Y.1
Kawano, S.2
Takenokuchi, M.3
Nishimura, K.4
Sakai, Y.5
Chin, T.6
-
48
-
-
52249094653
-
Upregulated miR- 146a expression in peripheral blood mononuclear cells from rheumatoid arthritis patients
-
Pauley KM, Satoh M, Chan AL, Bubb MR, Reeves WH, Chan EK. Upregulated miR- 146a expression in peripheral blood mononuclear cells from rheumatoid arthritis patients. Arthritis Res Ther. 2008;10: R101
-
(2008)
Arthritis Res Ther
, vol.10
-
-
Pauley, K.M.1
Satoh, M.2
Chan, A.L.3
Bubb, M.R.4
Reeves, W.H.5
Chan, E.K.6
-
49
-
-
79953023325
-
MicroRNAs in rheumatoid arthritis: Midget RNAs with a giant impact
-
Wittmann J, Jack HM. microRNAs in rheumatoid arthritis: midget RNAs with a giant impact. Ann RheumDis. 2011;70 Suppl 1:i92-96
-
(2011)
Ann RheumDis
, vol.70
, Issue.SUPPL. 1
-
-
Wittmann, J.1
Jack, H.M.2
-
51
-
-
84858703918
-
Novel regulatory mechanisms in inflammatory arthritis: A role for microRNA
-
Baxter D, McInnes IB, Kurowska-Stolarska M. Novel regulatory mechanisms in inflammatory arthritis: a role for microRNA. Immunol Cell Biol. 2012;90:288-92
-
(2012)
Immunol Cell Biol
, vol.90
, pp. 288-292
-
-
Baxter, D.1
McInnes, I.B.2
Kurowska-Stolarska, M.3
-
52
-
-
77958495102
-
MicroRNA-155 promotes autoimmune inflammation by enhancing inflammatory T cell development
-
O'Connell RM, Kahn D, Gibson WS, Round JL, Scholz RL, Chaudhuri AA, et l.MicroRNA-155 promotes autoimmune inflammation by enhancing inflammatory T cell development. Immunity. 2010;33:607-19
-
(2010)
Immunity
, vol.33
, pp. 607-619
-
-
O'connell, R.M.1
Kahn, D.2
Gibson, W.S.3
Round, J.L.4
Scholz, R.L.5
Chaudhuri, A.A.6
-
53
-
-
33646471662
-
Pre-B cell proliferation and lymphoblastic leukemia/high-grade lymphoma in E(mu)-miR155 transgenic mice
-
Costinean S, Zanesi N, Pekarsky Y, Tili E, Volinia S, Heerema N, et al. Pre-B cell proliferation and lymphoblastic leukemia/high-grade lymphoma in E(mu)-miR155 transgenic mice. Proc Natl Acad Sci U S A. 2006;103:7024-9
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 7024-7029
-
-
Costinean, S.1
Zanesi, N.2
Pekarsky, Y.3
Tili, E.4
Volinia, S.5
Heerema, N.6
-
54
-
-
77956511013
-
MicroRNA-146a expresses in interleukin-17 producing T cells in rheumatoid arthritis patients
-
Niimoto T, Nakasa T, Ishikawa M, Okuhara A, Izumi B, Deie M, et al. MicroRNA-146a expresses in interleukin-17 producing T cells in rheumatoid arthritis patients. BMC Musculoskelet Disord. 2010;11:209
-
(2010)
BMC Musculoskelet Disord
, vol.11
, pp. 209
-
-
Niimoto, T.1
Nakasa, T.2
Ishikawa, M.3
Okuhara, A.4
Izumi, B.5
Deie, M.6
-
55
-
-
42449156220
-
Altered expression of microRNA in synovial fibroblasts and synovial tissue in rheumatoid arthritis
-
DOI 10.1002/art.23386
-
Stanczyk J, Pedrioli DM, Brentano F, Sanchez-Pernaute O, Kolling C, Gay RE, et al. Altered expression of MicroRNA in synovial fibroblasts and synovial tissue in rheumatoid arthritis. Arthritis Rheum. 2008;58:1001-9 (Pubitemid 351564001)
-
(2008)
Arthritis and Rheumatism
, vol.58
, Issue.4
, pp. 1001-1009
-
-
Stanczyk, J.1
Leslie Pedrioli, D.M.2
Brentano, F.3
Sanchez-Pernaute, O.4
Kolling, C.5
Gay, R.E.6
Detmar, M.7
Gay, S.8
Kyburz, D.9
-
56
-
-
84866111542
-
Identification of microRNA-221/222 and microRNA-323-3p association with rheumatoid arthritis via predictions using the human tumour necrosis factor transgenic mouse model
-
Pandis I, Ospelt C, Karagianni N, Denis MC, Reczko M, Camps C, et al. Identification of microRNA-221/222 and microRNA-323-3p association with rheumatoid arthritis via predictions using the human tumour necrosis factor transgenic mouse model. Ann Rheum Dis. 2012;71:1716-23
-
(2012)
Ann Rheum Dis
, vol.71
, pp. 1716-1723
-
-
Pandis, I.1
Ospelt, C.2
Karagianni, N.3
Denis, M.C.4
Reczko, M.5
Camps, C.6
-
57
-
-
79960595150
-
MicroRNA-155 as a proinflammatory regulator in clinical and experimental arthritis
-
Preclinical validation of mIR155 as a target for RA and determination of the mechanism of action of mIR155 in the CIA model supporting a role in innate immunity
-
Kurowska-Stolarska M, Alivernini S, Ballantine LE, Asquith DL, Millar NL, Gilchrist DS, et al. MicroRNA-155 as a proinflammatory regulator in clinical and experimental arthritis. Proc Natl Acad Sci U S A. 2011;108:11193-8. Preclinical validation of mIR155 as a target for RA and determination of the mechanism of action of mIR155 in the CIA model supporting a role in innate immunity
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, pp. 11193-11198
-
-
Kurowska-Stolarska, M.1
Alivernini, S.2
Ballantine, L.E.3
Asquith, D.L.4
Millar, N.L.5
Gilchrist, D.S.6
-
58
-
-
79955561084
-
Essential role of microRNA-155 in the pathogenesis of autoimmune arthritis in mice
-
Preclinical validation of mIR155 as a target for RA and determination of the mechanism of action of mIR155 in the CIA model supporting a role in adaptive immunity and osteoclasts
-
Bluml S, Bonelli M, Niederreiter B, Puchner A,Mayr G, Hayer S, et al. Essential role of microRNA-155 in the pathogenesis of autoimmune arthritis in mice. Arthritis Rheum. 2011;63:1281-8. Preclinical validation of mIR155 as a target for RA and determination of the mechanism of action of mIR155 in the CIA model supporting a role in adaptive immunity and osteoclasts
-
(2011)
Arthritis Rheum
, vol.63
, pp. 1281-1288
-
-
Bluml, S.1
Bonelli, M.2
Niederreiter, B.3
Puchner, A.4
Mayr, G.5
Hayer, S.6
-
59
-
-
33747608638
-
NF-κB-dependent induction of microRNA miR-146, an inhibitor targeted to signaling proteins of innate immune responses
-
DOI 10.1073/pnas.0605298103
-
Taganov KD, Boldin MP, Chang KJ, Baltimore D. NF-kappaBdependent induction of microRNA miR-146, an inhibitor targeted to signaling proteins of innate immune responses. Proc Natl Acad Sci U S A. 2006;103:12481-6 (Pubitemid 44267285)
-
(2006)
Proceedings of the National Academy of Sciences of the United States of America
, vol.103
, Issue.33
, pp. 12481-12486
-
-
Taganov, K.D.1
Boldin, M.P.2
Chang, K.-J.3
Baltimore, D.4
-
60
-
-
43949136123
-
Expression of MicroRNA-146 in rheumatoid arthritis synovial tissue
-
DOI 10.1002/art.23429
-
Nakasa T, Miyaki S, Okubo A, Hashimoto M, Nishida K, Ochi M, et al. Expression of microRNA-146 in rheumatoid arthritis synovial tissue. Arthritis Rheum. 2008;58:1284-92 (Pubitemid 351705917)
-
(2008)
Arthritis and Rheumatism
, vol.58
, Issue.5
, pp. 1284-1292
-
-
Nakasa, T.1
Miyaki, S.2
Okubo, A.3
Hashimoto, M.4
Nishida, K.5
Ochi, M.6
Asahara, H.7
-
61
-
-
79958053053
-
The inhibitory effect of microRNA- 146a expression on bone destruction in collagen-induced arthritis
-
Nakasa T, Shibuya H, Nagata Y, Niimoto T, Ochi M. The inhibitory effect of microRNA- 146a expression on bone destruction in collagen-induced arthritis. Arthritis Rheum. 2011;63:1582-90
-
(2011)
Arthritis Rheum
, vol.63
, pp. 1582-1590
-
-
Nakasa, T.1
Shibuya, H.2
Nagata, Y.3
Niimoto, T.4
Ochi, M.5
-
62
-
-
77951973193
-
Altered microRNA expression profile with miR-146a upregulation in CD4+ T cells from patients with rheumatoid arthritis
-
Li J, Wan Y, Guo Q, Zou L, Zhang J, Fang Y, et al. Altered microRNA expression profile with miR-146a upregulation in CD4+ T cells from patients with rheumatoid arthritis. Arthritis Res Ther. 2010;12:R81
-
(2010)
Arthritis Res Ther
, vol.12
-
-
Li, J.1
Wan, Y.2
Guo, Q.3
Zou, L.4
Zhang, J.5
Fang, Y.6
-
63
-
-
84866605611
-
MiR-146a polymorphism is associated with asthma but not with systemic lupus erythematosus and juvenile rheumatoid arthritis in Mexican patients
-
Jimenez-Morales S, Gamboa-Becerra R, Baca V, Del Rio-Navarro BE, Lopez-Ley DY, elazquez-Cruz R, et al. MiR-146a polymorphism is associated with asthma but not with systemic lupus erythematosus and juvenile rheumatoid arthritis in Mexican patients. Tissue Antigens. 2012;80:317-21
-
(2012)
Tissue Antigens
, vol.80
, pp. 317-321
-
-
Jimenez-Morales, S.1
Gamboa-Becerra, R.2
Baca, V.3
Del Rio-Navarro, B.E.4
Lopez-Ley, D.Y.5
Velazquez-Cruz, R.6
-
64
-
-
84355161620
-
Association of polymorphisms in pre-miRNA with inflammatory biomarkers in rheumatoid arthritis in the Chinese Han population
-
Yang B, Chen J, Li Y, Zhang J, Li D, Huang Z, et al. Association of polymorphisms in pre-miRNA with inflammatory biomarkers in rheumatoid arthritis in the Chinese Han population. Hum Immunol. 2012;73:101-6
-
(2012)
Hum Immunol
, vol.73
, pp. 101-106
-
-
Yang, B.1
Chen, J.2
Li, Y.3
Zhang, J.4
Li, D.5
Huang, Z.6
-
65
-
-
77957873680
-
A polymorphism in the 3'-UTR of interleukin-1 receptor-associated kinase (IRAK1), a target gene of miR-146a, is associated with rheumatoid arthritis susceptibility
-
Chatzikyriakidou A, Voulgari PV, Georgiou I, Drosos AA. A polymorphism in the 3'-UTR of interleukin-1 receptor-associated kinase (IRAK1), a target gene of miR-146a, is associated with rheumatoid arthritis susceptibility. Joint, bone, spine : Revue du Rhumatisme. 2010;77:411-3
-
(2010)
Joint, Bone, Spine : Revue du Rhumatisme
, vol.77
, pp. 411-413
-
-
Chatzikyriakidou, A.1
Voulgari, P.V.2
Georgiou, I.3
Drosos, A.A.4
-
66
-
-
84855384226
-
TLR2 expression is regulated by microRNA miR-19 in rheumatoid fibroblast-like synoviocytes
-
Basal expression of mIR19 prevents innate responses in RA FLS
-
Philippe L, AlsalehG, Suffert G,MeyerA,Georgel P, Sibilia J, et al. TLR2 expression is regulated by microRNA miR-19 in rheumatoid fibroblast-like synoviocytes. J Immunol. 2012;188:454-61. Basal expression of mIR19 prevents innate responses in RA FLS
-
(2012)
J Immunol
, vol.188
, pp. 454-461
-
-
Philippe, L.1
Alsaleh, G.2
Suffert, G.3
Meyer, A.4
Georgel, P.5
Sibilia, J.6
-
67
-
-
84867898027
-
A miR-19 regulon that controls NFkappaB signaling
-
mIR19 is part of a positive feedback loop that promotes NFkB signaling in RA FLS
-
Gantier MP, Stunden HJ, McCoy CE, Behlke MA, Wang D, Kaparakis-Liaskos M, et al. A miR-19 regulon that controls NFkappaB signaling. Nucleic Acids Res. 2012;40:8048-58. mIR19 is part of a positive feedback loop that promotes NFkB signaling in RA FLS
-
(2012)
Nucleic Acids Res
, vol.40
, pp. 8048-8058
-
-
Gantier, M.P.1
Stunden, H.J.2
McCoy, C.E.3
Behlke, M.A.4
Wang, D.5
Kaparakis-Liaskos, M.6
-
68
-
-
84875721809
-
Tumor necrosis factor alpha-induced microRNA-18a activates rheumatoid arthritis synovial fibroblasts through a feedback loop in NFkappaB signaling
-
Trenkmann M, Brock M, Gay RE, Michel BA, Gay S, Huber LC. Tumor necrosis factor alpha-induced microRNA-18a activates rheumatoid arthritis synovial fibroblasts through a feedback loop in NFkappaB signaling. Arthritis Rheum. 2013;65:916-27
-
(2013)
Arthritis Rheum
, vol.65
, pp. 916-927
-
-
Trenkmann, M.1
Brock, M.2
Gay, R.E.3
Michel, B.A.4
Gay, S.5
Huber, L.C.6
-
69
-
-
74449090482
-
MiR- 223 is overexpressed in T-lymphocytes of patients affected by rheumatoid arthritis
-
Fulci V, Scappucci G, Sebastiani GD, Giannitti C, Franceschini D, Meloni F, et al. miR- 223 is overexpressed in T-lymphocytes of patients affected by rheumatoid arthritis. Hum Immunol. 2010;71: 206-11
-
(2010)
Hum Immunol
, vol.71
, pp. 206-211
-
-
Fulci, V.1
Scappucci, G.2
Sebastiani, G.D.3
Giannitti, C.4
Franceschini, D.5
Meloni, F.6
-
70
-
-
84869063724
-
Brief report: Amelioration of collagen-induced arthritis in mice by lentivirus-mediated silencing of microRNA-223
-
Li YT, Chen SY, Wang CR, Liu MF, Lin CC, Jou IM, et al. Brief report: amelioration of collagen-induced arthritis in mice by lentivirus-mediated silencing of microRNA-223. Arthritis Rheum. 2012;64:3240-5
-
(2012)
Arthritis Rheum
, vol.64
, pp. 3240-3045
-
-
Li, Y.T.1
Chen, S.Y.2
Wang, C.R.3
Liu, M.F.4
Lin, C.C.5
Jou, I.M.6
-
71
-
-
77952086523
-
Plasma and synovial fluid microRNAs as potential biomarkers of rheumatoid arthritis and osteoarthritis
-
Murata K, Yoshitomi H, Tanida S, Ishikawa M, Nishitani K, Ito H, et al. Plasma and synovial fluid microRNAs as potential biomarkers of rheumatoid arthritis and osteoarthritis. Arthritis Res Ther. 2010;12: R86
-
(2010)
Arthritis Res Ther
, vol.12
-
-
Murata, K.1
Yoshitomi, H.2
Tanida, S.3
Ishikawa, M.4
Nishitani, K.5
Ito, H.6
-
72
-
-
79551655444
-
Altered expression of microRNA-203 in rheumatoid arthritis synovial fibroblasts and its role in fibroblast activation
-
Stanczyk J, Ospelt C, Karouzakis E, Filer A, Raza K, Kolling C, et al. Altered expression of microRNA-203 in rheumatoid arthritis synovial fibroblasts and its role in fibroblast activation. Arthritis Rheum. 2011;63:373-81
-
(2011)
Arthritis Rheum
, vol.63
, pp. 373-381
-
-
Stanczyk, J.1
Ospelt, C.2
Karouzakis, E.3
Filer, A.4
Raza, K.5
Kolling, C.6
-
73
-
-
84857887315
-
Down-Regulation of microRNA-34a*in rheumatoid arthritis synovial fibroblasts promotes apoptosis resistance
-
Niederer F, Trenkmann M, Ospelt C, Karouzakis E, Neidhart M, Stanczyk J, et al. Down-regulation of microRNA-34a*in rheumatoid arthritis synovial fibroblasts promotes apoptosis resistance. Arthritis Rheum. 2012;64:1771-9
-
(2012)
Arthritis Rheum
, vol.64
, pp. 1771-1779
-
-
Niederer, F.1
Trenkmann, M.2
Ospelt, C.3
Karouzakis, E.4
Neidhart, M.5
Stanczyk, J.6
-
74
-
-
84863686039
-
ThemicroRNA miR-23b suppresses IL- 17-associated autoimmune inflammation by targeting TAB2, TAB3 and IKK-alpha
-
Identification of mIR23b as promoter IL-17 stimulated NFkB activation in RA and extensive characterization of its mechanism of action
-
Zhu S, PanW, SongX, LiuY, ShaoX, TangY, et al. ThemicroRNA miR-23b suppresses IL- 17-associated autoimmune inflammation by targeting TAB2, TAB3 and IKK-alpha. Nat Med. 2012;18:1077-86. Identification of mIR23b as promoter IL-17 stimulated NFkB activation in RA and extensive characterization of its mechanism of action
-
(2012)
Nat Med.
, vol.18
, pp. 1077-1086
-
-
Zhu, S.1
Pan, W.2
Song, X.3
Liu, Y.4
Shao, X.5
Tang, Y.6
-
75
-
-
65249088074
-
Bruton's tyrosine kinase is involved in miR-346-related regulation of IL-18 release by lipopolysaccharide-activated rheumatoid fibroblast-like synoviocytes
-
Alsaleh G, Suffert G, Semaan N, Juncker T, Frenzel L, Gottenberg JE, et al. Bruton's tyrosine kinase is involved in miR-346-related regulation of IL-18 release by lipopolysaccharide-activated rheumatoid fibroblast-like synoviocytes. J Immunol. 2009;182:5088-97
-
(2009)
J Immunol
, vol.182
, pp. 5088-5097
-
-
Alsaleh, G.1
Suffert, G.2
Semaan, N.3
Juncker, T.4
Frenzel, L.5
Gottenberg, J.E.6
-
76
-
-
79956089534
-
MiR-346 controls release of TNF-alpha protein and stability of its mRNA in rheumatoid arthritis via tristetraprolin stabilization
-
Semaan N, Frenzel L, Alsaleh G, Suffert G, Gottenberg JE, Sibilia J, et al. miR-346 controls release of TNF-alpha protein and stability of its mRNA in rheumatoid arthritis via tristetraprolin stabilization. PLoS One. 2011;6:e19827
-
(2011)
PLoS One
, vol.6
-
-
Semaan, N.1
Frenzel, L.2
Alsaleh, G.3
Suffert, G.4
Gottenberg, J.E.5
Sibilia, J.6
-
77
-
-
69449094454
-
Induction of apoptosis in the synovium of mice with autoantibody-mediated arthritis by the intraarticular injection of double-stranded MicroRNA-15a
-
Nagata Y, Nakasa T, Mochizuki Y, Ishikawa M, Miyaki S, Shibuya H, et al. Induction of apoptosis in the synovium of mice with autoantibody-mediated arthritis by the intraarticular injection of double-stranded MicroRNA-15a. Arthritis Rheum. 2009;60:2677-83
-
(2009)
Arthritis Rheum
, vol.60
, pp. 2677-2683
-
-
Nagata, Y.1
Nakasa, T.2
Mochizuki, Y.3
Ishikawa, M.4
Miyaki, S.5
Shibuya, H.6
|