-
1
-
-
84873956600
-
Global strategy for the diagnosis, management and prevention of chronic obstructive pulmonary disease, GOLD executive summary
-
Vestbo, J. et al. Global strategy for the diagnosis, management and prevention of chronic obstructive pulmonary disease, GOLD executive summary. Am. J. Respir. Crit. Care Med. 187, 347-365 (2013).
-
(2013)
Am. J. Respir. Crit. Care Med.
, vol.187
, pp. 347-365
-
-
Vestbo, J.1
-
2
-
-
84936762052
-
Lung-function trajectories leading to chronic obstructive pulmonary disease
-
Lange, P. et al. Lung-function trajectories leading to chronic obstructive pulmonary disease. N. Engl. J. Med. 373, 111-122 (2015).
-
(2015)
N. Engl. J. Med.
, vol.373
, pp. 111-122
-
-
Lange, P.1
-
3
-
-
84871036375
-
Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: A systematic for the Global Burden of Disease Study 2010
-
Lozano, R. et al. Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic for the Global Burden of Disease Study 2010. Lancet 380, 2095-2128 (2013).
-
(2013)
Lancet
, vol.380
, pp. 2095-2128
-
-
Lozano, R.1
-
4
-
-
84929011928
-
Global and regional trends in COPD mortality, 1990-2010
-
Burney, P. G., Patel, J., Newson, R., Minelli, C. & Naghavi, M. Global and regional trends in COPD mortality, 1990-2010. Eur. Respir. J. 45, 1239-1247 (2015).
-
(2015)
Eur. Respir. J.
, vol.45
, pp. 1239-1247
-
-
Burney, P.G.1
Patel, J.2
Newson, R.3
Minelli, C.4
Naghavi, M.5
-
5
-
-
80052747314
-
Lifetime risk of developing chronic obstructive pulmonary disease: A longitudinal population study
-
Gershon, A. S., Warner, L., Cascagnette, P., Victor, J. C. & To, T. Lifetime risk of developing chronic obstructive pulmonary disease: a longitudinal population study. Lancet 378, 991-996 (2011).
-
(2011)
Lancet
, vol.378
, pp. 991-996
-
-
Gershon, A.S.1
Warner, L.2
Cascagnette, P.3
Victor, J.C.4
To, T.5
-
6
-
-
72549095154
-
Prevalence of COPD among symptomatic patients in a primary care setting
-
Yawn, B. et al. Prevalence of COPD among symptomatic patients in a primary care setting. Curr. Med. Res. Opin. 25, 2671-2677 (2009).
-
(2009)
Curr. Med. Res. Opin.
, vol.25
, pp. 2671-2677
-
-
Yawn, B.1
-
7
-
-
34548267728
-
International variation in the prevalence of COPD (the BOLD study): A population-based prevalence study
-
Buist, A. S. et al. International variation in the prevalence of COPD (the BOLD study): a population-based prevalence study. Lancet 370, 741-750 (2007).
-
(2007)
Lancet
, vol.370
, pp. 741-750
-
-
Buist, A.S.1
-
8
-
-
38849171819
-
Tuberculosis and airflow obstruction: Evidence from the PLATINO study in Latin America
-
Menezes, A. M. et al. Tuberculosis and airflow obstruction: evidence from the PLATINO study in Latin America. Eur. Respir. J. 30, 1180-1185 (2007).
-
(2007)
Eur. Respir. J.
, vol.30
, pp. 1180-1185
-
-
Menezes, A.M.1
-
9
-
-
84861888193
-
Risk factors for COPD spirometrically defined from the lower limit of normal in the BOLD project
-
Hooper, R. et al. Risk factors for COPD spirometrically defined from the lower limit of normal in the BOLD project. Eur. Respir. J. 39, 1343-1353 (2012).
-
(2012)
Eur. Respir. J.
, vol.39
, pp. 1343-1353
-
-
Hooper, R.1
-
10
-
-
68649125058
-
Further exploration of the links between occupational exposure and chronic obstructive pulmonary disease
-
Blanc, P. D. et al. Further exploration of the links between occupational exposure and chronic obstructive pulmonary disease. J. Occup. Environ. Med. 51, 804-810 (2009).
-
(2009)
J. Occup. Environ. Med.
, vol.51
, pp. 804-810
-
-
Blanc, P.D.1
-
11
-
-
0019360546
-
The relation of mortality in England and Wales 1969-1973 to measurements of air pollution
-
Chinn, S., Florey, C. D., Baldwin, I. G. & Gorgol, M. The relation of mortality in England and Wales 1969-1973 to measurements of air pollution. J. Epidemiol. Commun. Health 35, 174-179 (1981).
-
(1981)
J. Epidemiol. Commun. Health
, vol.35
, pp. 174-179
-
-
Chinn, S.1
Florey, C.D.2
Baldwin, I.G.3
Gorgol, M.4
-
12
-
-
69149102202
-
Chronic obstructive pulmonary disease in non-smokers
-
Salvi, S. & Barnes, P. Chronic obstructive pulmonary disease in non-smokers. Lancet 374, 733-743 (2009).
-
(2009)
Lancet
, vol.374
, pp. 733-743
-
-
Salvi, S.1
Barnes, P.2
-
13
-
-
84897077822
-
An integrated risk function for estimating the global burden of disease attributable to ambient fine particulate patter exposure
-
Burnett, R. T. et al. An integrated risk function for estimating the global burden of disease attributable to ambient fine particulate patter exposure. Environ. Health Persp. 122, 397-403 (2014).
-
(2014)
Environ. Health Persp.
, vol.122
, pp. 397-403
-
-
Burnett, R.T.1
-
14
-
-
70349468017
-
Improved biomass stove intervention in rural Mexico: Impact on the respiratory health of women
-
Romieu, I. et al. Improved biomass stove intervention in rural Mexico: impact on the respiratory health of women. Am. J. Respir. Crit. Care Med. 180, 649-656 (2009).
-
(2009)
Am. J. Respir. Crit. Care Med.
, vol.180
, pp. 649-656
-
-
Romieu, I.1
-
15
-
-
84898951625
-
Lung function and incidence of chronic obstructive pulmonary disease after improved cooking fuels and kitchen ventilation: A 9-year prospective cohort study
-
Zhou, Y. et al. Lung function and incidence of chronic obstructive pulmonary disease after improved cooking fuels and kitchen ventilation: a 9-year prospective cohort study. PLoS Med. 11, e1001621 (2014).
-
(2014)
PLoS Med.
, vol.11
-
-
Zhou, Y.1
-
16
-
-
84903851432
-
Prevalence and correlates of airflow obstruction in 317,000 never-smokers in China
-
Smith, M. et al. Prevalence and correlates of airflow obstruction in 317,000 never-smokers in China. Eur. Respir. J. 44, 66-77 (2014).
-
(2014)
Eur. Respir. J.
, vol.44
, pp. 66-77
-
-
Smith, M.1
-
17
-
-
84898655103
-
Chronic obstructive pulmonary disease mortality and prevalence: The associations with smoking and poverty - A BOLD analysis
-
Burney, P. et al. Chronic obstructive pulmonary disease mortality and prevalence: the associations with smoking and poverty - a BOLD analysis. Thorax 69, 465-473 (2014).
-
(2014)
Thorax
, vol.69
, pp. 465-473
-
-
Burney, P.1
-
19
-
-
0002462253
-
-
eds Charlton, J. & Murphy, M.) Her Majesty's Stationery Office
-
Marks, G. & Burney, P. in The Health of Adult Britain 1841-1991 Vol. 2 (eds Charlton, J. & Murphy, M.) 93-113 (Her Majesty's Stationery Office, 1997).
-
(1997)
The Health of Adult Britain 1841-1991
, vol.2
, pp. 93-113
-
-
Marks, G.1
Burney, P.2
-
20
-
-
0023022245
-
Childhood respiratory infection and adult chronic bronchitis in England and Wales
-
Barker, D. J. & Osmond, C. Childhood respiratory infection and adult chronic bronchitis in England and Wales. BMJ (Clin. Res. Ed.) 293, 1271-1275 (1986).
-
(1986)
BMJ (Clin. Res. Ed.)
, vol.293
, pp. 1271-1275
-
-
Barker, D.J.1
Osmond, C.2
-
21
-
-
84918793208
-
Gaps in using bronchodilators, inhaled corticosteroids and influenza vaccine among 23 high-and low-income sites
-
Gnatiuc, L. et al. Gaps in using bronchodilators, inhaled corticosteroids and influenza vaccine among 23 high-and low-income sites. Int. J. Tuberc. Lung Dis. 19, 21-30 (2015).
-
(2015)
Int. J. Tuberc. Lung Dis.
, vol.19
, pp. 21-30
-
-
Gnatiuc, L.1
-
22
-
-
78650029099
-
Genetic influences on chronic obstructive pulmonary disease - A twin study
-
Ingebrigtsen, T. et al. Genetic influences on chronic obstructive pulmonary disease - a twin study. Respir. Med. 104, 1890-1895 (2010).
-
(2010)
Respir. Med.
, vol.104
, pp. 1890-1895
-
-
Ingebrigtsen, T.1
-
23
-
-
0035888763
-
Siblings of patients with severe chronic obstructive pulmonary disease have a significant risk of airflow obstruction
-
McCloskey, S. C. et al. Siblings of patients with severe chronic obstructive pulmonary disease have a significant risk of airflow obstruction. Am. J. Respir. Crit. Care Med. 164, 1419-1424 (2001).
-
(2001)
Am. J. Respir. Crit. Care Med.
, vol.164
, pp. 1419-1424
-
-
McCloskey, S.C.1
-
24
-
-
0031807729
-
Genetic epidemiology of severe, early-onset chronic obstructive pulmonary disease: Risk to relatives for airflow obstruction and chronic bronchitis
-
Silverman, E. K. et al. Genetic epidemiology of severe, early-onset chronic obstructive pulmonary disease: risk to relatives for airflow obstruction and chronic bronchitis. Am. J. Respir. Crit. Care Med. 157, 1770-1778 (1998).
-
(1998)
Am. J. Respir. Crit. Care Med.
, vol.157
, pp. 1770-1778
-
-
Silverman, E.K.1
-
25
-
-
84886403801
-
Heritability of chronic obstructive pulmonary disease and related phenotypes in smokers
-
Zhou, J. J. et al. Heritability of chronic obstructive pulmonary disease and related phenotypes in smokers. Am. J. Respir. Crit. Care Med. 188, 941-947 (2013).
-
(2013)
Am. J. Respir. Crit. Care Med.
, vol.188
, pp. 941-947
-
-
Zhou, J.J.1
-
26
-
-
67649390890
-
Clinical practice. Alpha1-antitrypsin deficiency
-
Silverman, E. K. & Sandhaus, R. A. Clinical practice. Alpha1-antitrypsin deficiency. N. Engl. J. Med. 360, 2749-2757 (2009).
-
(2009)
N. Engl. J. Med.
, vol.360
, pp. 2749-2757
-
-
Silverman, E.K.1
Sandhaus, R.A.2
-
27
-
-
78349265383
-
α1-Antitrypsin protease inhibitor MZ heterozygosity is associated with airflow obstruction in two large cohorts
-
Sorheim, I. C. et al. α1-Antitrypsin protease inhibitor MZ heterozygosity is associated with airflow obstruction in two large cohorts. Chest 138, 1125-1132 (2010).
-
(2010)
Chest
, vol.138
, pp. 1125-1132
-
-
Sorheim, I.C.1
-
28
-
-
84894271236
-
Clarification of the risk of chronic obstructive pulmonary disease in α1-antitrypsin deficiency PiMZ heterozygotes
-
Molloy, K. et al. Clarification of the risk of chronic obstructive pulmonary disease in α1-antitrypsin deficiency PiMZ heterozygotes. Am. J. Respir. Crit. Care Med. 189, 419-427 (2014).
-
(2014)
Am. J. Respir. Crit. Care Med.
, vol.189
, pp. 419-427
-
-
Molloy, K.1
-
29
-
-
4544258054
-
A novel elastin gene mutation resulting in an autosomal dominant form of cutis laxa
-
Rodriguez-Revenga, L. et al. A novel elastin gene mutation resulting in an autosomal dominant form of cutis laxa. Arch. Dermatol. 140, 1135-1139 (2004).
-
(2004)
Arch. Dermatol.
, vol.140
, pp. 1135-1139
-
-
Rodriguez-Revenga, L.1
-
30
-
-
26244453991
-
A functional mutation in the terminal exon of elastin in severe, early-onset chronic obstructive pulmonary disease
-
Kelleher, C. M. et al. A functional mutation in the terminal exon of elastin in severe, early-onset chronic obstructive pulmonary disease. Am. J. Respir. Cell. Mol. Biol. 33, 355-362 (2005).
-
(2005)
Am. J. Respir. Cell. Mol. Biol.
, vol.33
, pp. 355-362
-
-
Kelleher, C.M.1
-
31
-
-
84901625706
-
Whole exome re-sequencing implicates CCDC38 and cilia structure and function in resistance to smoking related airflow obstruction
-
Wain, L. V. et al. Whole exome re-sequencing implicates CCDC38 and cilia structure and function in resistance to smoking related airflow obstruction. PLoS Genet. 10, e1004314 (2014).
-
(2014)
PLoS Genet.
, vol.10
-
-
Wain, L.V.1
-
32
-
-
77949911882
-
The COPD genetic association compendium: A comprehensive online database of COPD genetic associations
-
Castaldi, P. J. et al. The COPD genetic association compendium: a comprehensive online database of COPD genetic associations. Hum. Mol. Genet. 19, 526-534 (2010).
-
(2010)
Hum. Mol. Genet.
, vol.19
, pp. 526-534
-
-
Castaldi, P.J.1
-
33
-
-
70349449892
-
Meta-analyses on suspected chronic obstructive pulmonary disease genes: A summary of 20 years' research
-
Smolonska, J., Wijmenga, C., Postma, D. S. & Boezen, H. M. Meta-analyses on suspected chronic obstructive pulmonary disease genes: a summary of 20 years' research. Am. J. Respir. Crit. Care Med. 180, 618-631 (2009).
-
(2009)
Am. J. Respir. Crit. Care Med.
, vol.180
, pp. 618-631
-
-
Smolonska, J.1
Wijmenga, C.2
Postma, D.S.3
Boezen, H.M.4
-
34
-
-
84895799527
-
Risk loci for chronic obstructive pulmonary disease: A genome-wide association study and meta-analysis
-
Cho, M. H. et al. Risk loci for chronic obstructive pulmonary disease: a genome-wide association study and meta-analysis. Lancet Respir. Med. 2, 214-225 (2014).
-
(2014)
Lancet Respir. Med.
, vol.2
, pp. 214-225
-
-
Cho, M.H.1
-
35
-
-
73349111257
-
Meta-analyses of genome-wide association studies identify multiple loci associated with pulmonary function
-
Hancock, D. B. et al. Meta-analyses of genome-wide association studies identify multiple loci associated with pulmonary function. Nat. Genet. 42, 45-52 (2010).
-
(2010)
Nat. Genet.
, vol.42
, pp. 45-52
-
-
Hancock, D.B.1
-
36
-
-
73349143302
-
Genome-wide association study identifies five loci associated with lung function
-
Repapi, E. et al. Genome-wide association study identifies five loci associated with lung function. Nat. Genet. 42, 36-44 (2010).
-
(2010)
Nat. Genet.
, vol.42
, pp. 36-44
-
-
Repapi, E.1
-
37
-
-
80055008094
-
Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function
-
Soler Artigas, M. et al. Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function. Nat. Genet. 43, 1082-1090 (2011).
-
(2011)
Nat. Genet.
, vol.43
, pp. 1082-1090
-
-
Soler Artigas, M.1
-
38
-
-
84907820687
-
Genome-wide association identifies regulatory loci associated with distinct local histogram emphysema patterns
-
Castaldi, P. J. et al. Genome-wide association identifies regulatory loci associated with distinct local histogram emphysema patterns. Am. J. Respir. Crit. Care Med. 190, 399-409 (2014).
-
(2014)
Am. J. Respir. Crit. Care Med.
, vol.190
, pp. 399-409
-
-
Castaldi, P.J.1
-
39
-
-
80053272831
-
Genome-wide association study of smoking behaviours in patients with COPD
-
Siedlinski, M. et al. Genome-wide association study of smoking behaviours in patients with COPD. Thorax 66, 894-902 (2011).
-
(2011)
Thorax
, vol.66
, pp. 894-902
-
-
Siedlinski, M.1
-
40
-
-
77951748276
-
Sequence variants at CHRNB3-CHRNA6 and CYP2A6 affect smoking behavior
-
Thorgeirsson, T. E. et al. Sequence variants at CHRNB3-CHRNA6 and CYP2A6 affect smoking behavior. Nat. Genet. 42, 448-453 (2010).
-
(2010)
Nat. Genet.
, vol.42
, pp. 448-453
-
-
Thorgeirsson, T.E.1
-
41
-
-
42649091460
-
Genome-wide association scan of tag SNPs identifies a susceptibility locus for lung cancer at 15q25.1
-
Amos, C. I. et al. Genome-wide association scan of tag SNPs identifies a susceptibility locus for lung cancer at 15q25.1. Nat. Genet. 40, 616-622 (2008).
-
(2008)
Nat. Genet.
, vol.40
, pp. 616-622
-
-
Amos, C.I.1
-
42
-
-
41649103052
-
A variant associated with nicotine dependence, lung cancer and peripheral arterial disease
-
Thorgeirsson, T. E. et al. A variant associated with nicotine dependence, lung cancer and peripheral arterial disease. Nature 452, 638-642 (2008).
-
(2008)
Nature
, vol.452
, pp. 638-642
-
-
Thorgeirsson, T.E.1
-
43
-
-
70350512132
-
Integration of genomic and genetic approaches implicates IREB2 as a COPD susceptibility gene
-
DeMeo, D. L. et al. Integration of genomic and genetic approaches implicates IREB2 as a COPD susceptibility gene. Am. J. Hum. Genet. 85, 493-502 (2009).
-
(2009)
Am. J. Hum. Genet.
, vol.85
, pp. 493-502
-
-
DeMeo, D.L.1
-
44
-
-
84876496349
-
Dissecting direct and indirect genetic effects on chronic obstructive pulmonary disease (COPD) susceptibility
-
Siedlinski, M. et al. Dissecting direct and indirect genetic effects on chronic obstructive pulmonary disease (COPD) susceptibility. Hum. Genet. 132, 431-441 (2013).
-
(2013)
Hum. Genet.
, vol.132
, pp. 431-441
-
-
Siedlinski, M.1
-
45
-
-
84863279822
-
Identification of a chronic obstructive pulmonary disease genetic determinant that regulates HHIP
-
Zhou, X. et al. Identification of a chronic obstructive pulmonary disease genetic determinant that regulates HHIP. Hum. Mol. Genet. 21, 1325-1335 (2012).
-
(2012)
Hum. Mol. Genet.
, vol.21
, pp. 1325-1335
-
-
Zhou, X.1
-
46
-
-
84928820273
-
Haploinsufficiency of Hedgehog interacting protein causes increased emphysema induced by cigarette smoke through network rewiring
-
Lao, T. et al. Haploinsufficiency of Hedgehog interacting protein causes increased emphysema induced by cigarette smoke through network rewiring. Genome Med. 7, 12 (2015).
-
(2015)
Genome Med.
, vol.7
, pp. 12
-
-
Lao, T.1
-
47
-
-
84922438551
-
Genetic control of gene expression at novel and established chronic obstructive pulmonary disease loci
-
Castaldi, P. J. et al. Genetic control of gene expression at novel and established chronic obstructive pulmonary disease loci. Hum. Mol. Genet. 24, 1200-1210 (2015).
-
(2015)
Hum. Mol. Genet.
, vol.24
, pp. 1200-1210
-
-
Castaldi, P.J.1
-
48
-
-
84857381360
-
Variable DNA methylation is associated with chronic obstructive pulmonary disease and lung function
-
Qiu, W. et al. Variable DNA methylation is associated with chronic obstructive pulmonary disease and lung function. Am. J. Respir. Crit. Care Med. 185, 373-381 (2012).
-
(2012)
Am. J. Respir. Crit. Care Med.
, vol.185
, pp. 373-381
-
-
Qiu, W.1
-
49
-
-
66149093072
-
The pathology of chronic obstructive pulmonary disease
-
Hogg, J. C. & Timens, W. The pathology of chronic obstructive pulmonary disease. Annu. Rev. Pathol. 4, 435-459 (2009).
-
(2009)
Annu. Rev. Pathol.
, vol.4
, pp. 435-459
-
-
Hogg, J.C.1
Timens, W.2
-
50
-
-
84862833566
-
Small-airway obstruction and emphysema in chronic obstructive pulmonary disease
-
McDonough, J. E. et al. Small-airway obstruction and emphysema in chronic obstructive pulmonary disease. N. Engl. J. Med. 365, 1567-1575 (2011).
-
(2011)
N. Engl. J. Med.
, vol.365
, pp. 1567-1575
-
-
McDonough, J.E.1
-
51
-
-
84869190518
-
Computed tomography-based biomarker provides unique signature for diagnosis of COPD phenotypes and disease progression
-
Galban, C. J. et al. Computed tomography-based biomarker provides unique signature for diagnosis of COPD phenotypes and disease progression. Nat. Med. 18, 1711-1715 (2012).
-
(2012)
Nat. Med.
, vol.18
, pp. 1711-1715
-
-
Galban, C.J.1
-
52
-
-
54249131732
-
Pulmonary vascular involvement in COPD
-
Peinado, V. I., Pizarro, S. & Barbera, J. A. Pulmonary vascular involvement in COPD. Chest 134, 808-814 (2008).
-
(2008)
Chest
, vol.134
, pp. 808-814
-
-
Peinado, V.I.1
Pizarro, S.2
Barbera, J.A.3
-
53
-
-
84890783241
-
Pulmonary hypertension in chronic lung diseases
-
Seeger, W. et al. Pulmonary hypertension in chronic lung diseases. J. Am. Coll. Cardiol. 62, D109-D116 (2013).
-
(2013)
J. Am. Coll. Cardiol.
, vol.62
, pp. D109-D116
-
-
Seeger, W.1
-
54
-
-
84893771777
-
Cellular and molecular mechanisms of chronic obstructive pulmonary disease
-
Barnes, P. J. Cellular and molecular mechanisms of chronic obstructive pulmonary disease. Clin. Chest Med. 35, 71-86 (2014).
-
(2014)
Clin. Chest Med.
, vol.35
, pp. 71-86
-
-
Barnes, P.J.1
-
55
-
-
80052706801
-
New insights into the immunology of chronic obstructive pulmonary disease
-
Brusselle, G. G., Joos, G. F. & Bracke, K. R. New insights into the immunology of chronic obstructive pulmonary disease. Lancet 378, 1015-1026 (2011).
-
(2011)
Lancet
, vol.378
, pp. 1015-1026
-
-
Brusselle, G.G.1
Joos, G.F.2
Bracke, K.R.3
-
56
-
-
40049104892
-
Immunology of asthma and chronic obstructive pulmonary disease
-
Barnes, P. J. Immunology of asthma and chronic obstructive pulmonary disease. Nat. Immunol. Rev. 8, 183-192 (2008).
-
(2008)
Nat. Immunol. Rev.
, vol.8
, pp. 183-192
-
-
Barnes, P.J.1
-
57
-
-
84902603074
-
Directing traffic: IL-17 and IL-22 coordinate pulmonary immune defense
-
McAleer, J. P. & Kolls, J. K. Directing traffic: IL-17 and IL-22 coordinate pulmonary immune defense. Immunol. Rev. 260, 129-144 (2014).
-
(2014)
Immunol. Rev.
, vol.260
, pp. 129-144
-
-
McAleer, J.P.1
Kolls, J.K.2
-
58
-
-
84918514503
-
The asthma-chronic obstructive pulmonary disease overlap syndrome (ACOS): Opportunities and challenges
-
Barrecheguren, M., Esquinas, C. & Miravitlles, M. The asthma-chronic obstructive pulmonary disease overlap syndrome (ACOS): opportunities and challenges. Curr. Opin. Pulm. Med. 21, 74-79 (2015).
-
(2015)
Curr. Opin. Pulm. Med.
, vol.21
, pp. 74-79
-
-
Barrecheguren, M.1
Esquinas, C.2
Miravitlles, M.3
-
59
-
-
55849148482
-
Cytokine networks in asthma and chronic obstructive pulmonary disease
-
Barnes, P. J. Cytokine networks in asthma and chronic obstructive pulmonary disease. J. Clin. Invest. 118, 3546-3556 (2008).
-
(2008)
J. Clin. Invest.
, vol.118
, pp. 3546-3556
-
-
Barnes, P.J.1
-
60
-
-
18544383099
-
Increased expression of NF-κB in bronchial biopsies from smokers and patients with COPD
-
Di Stefano, A. et al. Increased expression of NF-κB in bronchial biopsies from smokers and patients with COPD. Eur. Respir. J. 20, 556-563 (2002).
-
(2002)
Eur. Respir. J.
, vol.20
, pp. 556-563
-
-
Di Stefano, A.1
-
61
-
-
44649153952
-
Increased activation of p38 MAPK in COPD
-
Renda, T. et al. Increased activation of p38 MAPK in COPD. Eur. Respir. J. 31, 62-69 (2008).
-
(2008)
Eur. Respir. J.
, vol.31
, pp. 62-69
-
-
Renda, T.1
-
62
-
-
21044458874
-
Decreased histone deacetylase activity in chronic obstructive pulmonary disease
-
Ito, K. et al. Decreased histone deacetylase activity in chronic obstructive pulmonary disease. N. Engl. J. Med. 352, 1967-1976 (2005).
-
(2005)
N. Engl. J. Med.
, vol.352
, pp. 1967-1976
-
-
Ito, K.1
-
63
-
-
77951962615
-
Defective macrophage phagocytosis of bacteria in COPD
-
Taylor, A. E. et al. Defective macrophage phagocytosis of bacteria in COPD. Eur. Respir. J. 35, 1039-1047 (2010).
-
(2010)
Eur. Respir. J.
, vol.35
, pp. 1039-1047
-
-
Taylor, A.E.1
-
64
-
-
84859508650
-
Defective phagocytosis in airways disease
-
Donnelly, L. E. & Barnes, P. J. Defective phagocytosis in airways disease. Chest 141, 1055-1062 (2012).
-
(2012)
Chest
, vol.141
, pp. 1055-1062
-
-
Donnelly, L.E.1
Barnes, P.J.2
-
65
-
-
84910091190
-
Inflammatory thresholds and the species-specific effects of colonising bacteria in stable chronic obstructive pulmonary disease
-
Singh, R. et al. Inflammatory thresholds and the species-specific effects of colonising bacteria in stable chronic obstructive pulmonary disease. Respir. Res. 15, 114 (2014).
-
(2014)
Respir. Res.
, vol.15
, pp. 114
-
-
Singh, R.1
-
66
-
-
79952766005
-
Airway clearance of apoptotic cells in COPD
-
Mukaro, V. R. & Hodge, S. Airway clearance of apoptotic cells in COPD. Curr. Drug Targets 12, 460-468 (2011).
-
(2011)
Curr. Drug Targets
, vol.12
, pp. 460-468
-
-
Mukaro, V.R.1
Hodge, S.2
-
67
-
-
80053428842
-
Oxidative stress-induced antibodies to carbonyl-modified protein correlate with severity of COPD
-
Kirkham, P. A. et al. Oxidative stress-induced antibodies to carbonyl-modified protein correlate with severity of COPD. Am. J. Respir. Crit. Care Med. 184, 796-802 (2011).
-
(2011)
Am. J. Respir. Crit. Care Med.
, vol.184
, pp. 796-802
-
-
Kirkham, P.A.1
-
68
-
-
77950653061
-
Chronic obstructive pulmonary disease: Effects beyond the lungs
-
Barnes, P. J. Chronic obstructive pulmonary disease: effects beyond the lungs. PLoS Med. 7, e1000220 (2010).
-
(2010)
PLoS Med.
, vol.7
-
-
Barnes, P.J.1
-
69
-
-
84862100999
-
Persistent systemic inflammation is associated with poor clinical outcomes in COPD: A novel phenotype
-
Agusti, A. et al. Persistent systemic inflammation is associated with poor clinical outcomes in COPD: a novel phenotype. PLoS ONE 7, e37483 (2012).
-
(2012)
PLoS ONE
, vol.7
-
-
Agusti, A.1
-
70
-
-
58249099942
-
COPD as a disease of accelerated lung aging
-
Ito, K. & Barnes, P. J. COPD as a disease of accelerated lung aging. Chest 135, 173-180 (2009).
-
(2009)
Chest
, vol.135
, pp. 173-180
-
-
Ito, K.1
Barnes, P.J.2
-
71
-
-
84929466240
-
Accelerated ageing in chronic obstructive pulmonary disease: New concepts
-
Mercado, N., Ito, K. & Barnes, P. J. Accelerated ageing in chronic obstructive pulmonary disease: new concepts. Thorax 70, 482-489 (2015).
-
(2015)
Thorax
, vol.70
, pp. 482-489
-
-
Mercado, N.1
Ito, K.2
Barnes, P.J.3
-
72
-
-
84890451565
-
Dysfunction of endothelial progenitor cells from smokers and COPD patients due to increased DNA damage and senescence
-
Paschalaki, K. E. et al. Dysfunction of endothelial progenitor cells from smokers and COPD patients due to increased DNA damage and senescence. Stem Cells 31, 2813-2826 (2013).
-
(2013)
Stem Cells
, vol.31
, pp. 2813-2826
-
-
Paschalaki, K.E.1
-
73
-
-
84924006883
-
Mechanisms of development of multimorbidity in the elderly
-
Barnes, P. J. Mechanisms of development of multimorbidity in the elderly. Eur. Respir. J. 45, 790-806 (2015).
-
(2015)
Eur. Respir. J.
, vol.45
, pp. 790-806
-
-
Barnes, P.J.1
-
74
-
-
84920421073
-
Essential role for autophagy in life span extension
-
Madeo, F., Zimmermann, A., Maiuri, M. C. & Kroemer, G. Essential role for autophagy in life span extension. J. Clin. Invest. 125, 85-93 (2015).
-
(2015)
J. Clin. Invest.
, vol.125
, pp. 85-93
-
-
Madeo, F.1
Zimmermann, A.2
Maiuri, M.C.3
Kroemer, G.4
-
75
-
-
84868611206
-
The emerging importance of autophagy in pulmonary diseases
-
Mizumura, K., Cloonan, S. M., Haspel, J. A. & Choi, A. M. The emerging importance of autophagy in pulmonary diseases. Chest 142, 1289-1299 (2012).
-
(2012)
Chest
, vol.142
, pp. 1289-1299
-
-
Mizumura, K.1
Cloonan, S.M.2
Haspel, J.A.3
Choi, A.M.4
-
76
-
-
84880079298
-
Oxidative stress in COPD
-
Kirkham, P. A. & Barnes, P. J. Oxidative stress in COPD. Chest 144, 266-273 (2013).
-
(2013)
Chest
, vol.144
, pp. 266-273
-
-
Kirkham, P.A.1
Barnes, P.J.2
-
77
-
-
79956366064
-
Unbalanced oxidant-induced DNA damage and repair in COPD: A link towards lung cancer
-
Caramori, G. et al. Unbalanced oxidant-induced DNA damage and repair in COPD: a link towards lung cancer. Thorax 66, 521-527 (2011).
-
(2011)
Thorax
, vol.66
, pp. 521-527
-
-
Caramori, G.1
-
78
-
-
84875225940
-
Corticosteroid resistance in patients with asthma and chronic obstructive pulmonary disease
-
Barnes, P. J. Corticosteroid resistance in patients with asthma and chronic obstructive pulmonary disease. J. Allergy Clin. Immunol. 131, 636-645 (2013).
-
(2013)
J. Allergy Clin. Immunol.
, vol.131
, pp. 636-645
-
-
Barnes, P.J.1
-
79
-
-
70349324812
-
A protein deacetylase SIRT1 is a negative regulator of metalloproteinase-9
-
Nakamaru, Y. et al. A protein deacetylase SIRT1 is a negative regulator of metalloproteinase-9. FASEB J. 23, 2810-2819 (2009).
-
(2009)
FASEB J.
, vol.23
, pp. 2810-2819
-
-
Nakamaru, Y.1
-
80
-
-
51849129227
-
Expression of concern: Decline in NRF2 regulated antioxidants in COPD lungs due to loss of its positive regulator DJ-1
-
Malhotra, D. et al. Expression of concern: decline in NRF2 regulated antioxidants in COPD lungs due to loss of its positive regulator DJ-1. Am. J. Respir. Crit. Care Med. 178, 592-604 (2008).
-
(2008)
Am. J. Respir. Crit. Care Med.
, vol.178
, pp. 592-604
-
-
Malhotra, D.1
-
81
-
-
79952439646
-
Decreased histone deacetylase 2 impairs Nrf2 activation by oxidative stress
-
Mercado, N. et al. Decreased histone deacetylase 2 impairs Nrf2 activation by oxidative stress. Biochem. Biophys. Res. Commun. 406, 292-298 (2011).
-
(2011)
Biochem. Biophys. Res. Commun.
, vol.406
, pp. 292-298
-
-
Mercado, N.1
-
82
-
-
84887581901
-
Mitochondrial fragmentation in cigarette smoke-induced bronchial epithelial cell senescence
-
Hara, H. et al. Mitochondrial fragmentation in cigarette smoke-induced bronchial epithelial cell senescence. Am. J. Physiol. Lung Cell. Mol. Physiol. 305, L737-L746 (2013).
-
(2013)
Am. J. Physiol. Lung Cell. Mol. Physiol.
, vol.305
, pp. L737-L746
-
-
Hara, H.1
-
83
-
-
84907010947
-
Mitophagy-dependent necroptosis contributes to the pathogenesis of COPD
-
Mizumura, K. et al. Mitophagy-dependent necroptosis contributes to the pathogenesis of COPD. J. Clin. Invest. 124, 3987-4003 (2014).
-
(2014)
J. Clin. Invest.
, vol.124
, pp. 3987-4003
-
-
Mizumura, K.1
-
84
-
-
84864778678
-
Does dynamic hyperinflation contribute to dyspnoea during exercise in patients with COPD?
-
Guenette, J. A., Webb, K. A. & O'Donnell, D. E. Does dynamic hyperinflation contribute to dyspnoea during exercise in patients with COPD? Eur. Respir. J. 40, 322-329 (2012).
-
(2012)
Eur. Respir. J.
, vol.40
, pp. 322-329
-
-
Guenette, J.A.1
Webb, K.A.2
O'Donnell, D.E.3
-
85
-
-
34548290964
-
COPD exacerbations: Defining their cause and prevention
-
Wedzicha, J. A. & Seemungal, T. A. COPD exacerbations: defining their cause and prevention. Lancet 370, 786-796 (2007).
-
(2007)
Lancet
, vol.370
, pp. 786-796
-
-
Wedzicha, J.A.1
Seemungal, T.A.2
-
86
-
-
0035509117
-
Respiratory viruses, symptoms, and inflammatory markers in acute exacerbations and stable chronic obstructive pulmonary disease
-
Seemungal, T. et al. Respiratory viruses, symptoms, and inflammatory markers in acute exacerbations and stable chronic obstructive pulmonary disease. Am. J. Respir. Crit. Care Med. 164, 1618-1623 (2001).
-
(2001)
Am. J. Respir. Crit. Care Med.
, vol.164
, pp. 1618-1623
-
-
Seemungal, T.1
-
87
-
-
84903847406
-
Human rhinovirus infection during naturally occurring COPD exacerbations
-
George, S. N. et al. Human rhinovirus infection during naturally occurring COPD exacerbations. Eur. Respir. J. 44, 87-96 (2014).
-
(2014)
Eur. Respir. J.
, vol.44
, pp. 87-96
-
-
George, S.N.1
-
88
-
-
79959321052
-
Outdoor air pollution and respiratory health in patients with COPD
-
Peacock, J. L. et al. Outdoor air pollution and respiratory health in patients with COPD. Thorax 66, 591-596 (2011).
-
(2011)
Thorax
, vol.66
, pp. 591-596
-
-
Peacock, J.L.1
-
89
-
-
0031746535
-
Effect of exacerbation on quality of life in patients with chronic obstructive pulmonary disease
-
Seemungal, T. A. et al. Effect of exacerbation on quality of life in patients with chronic obstructive pulmonary disease. Am. J. Respir. Crit. Care Med. 157, 1418-1422 (1998).
-
(1998)
Am. J. Respir. Crit. Care Med.
, vol.157
, pp. 1418-1422
-
-
Seemungal, T.A.1
-
90
-
-
77956689733
-
Susceptibility to exacerbation in chronic obstructive pulmonary disease
-
Hurst, J. R. et al. Susceptibility to exacerbation in chronic obstructive pulmonary disease. N. Engl. J. Med. 363, 1128-1138 (2010).
-
(2010)
N. Engl. J. Med.
, vol.363
, pp. 1128-1138
-
-
Hurst, J.R.1
-
91
-
-
84887909801
-
Mechanisms and impact of the frequent exacerbator phenotype in chronic obstructive pulmonary disease
-
Wedzicha, J. A., Brill, S. E., Allinson, J. P. & Donaldson, G. C. Mechanisms and impact of the frequent exacerbator phenotype in chronic obstructive pulmonary disease. BMC Med. 11, 181 (2013).
-
(2013)
BMC Med.
, vol.11
, pp. 181
-
-
Wedzicha, J.A.1
Brill, S.E.2
Allinson, J.P.3
Donaldson, G.C.4
-
92
-
-
1842552109
-
Standards for the diagnosis and treatment of patients with COPD: A summary of the ATS/ERS position paper
-
Celli, B. R. & MacNee, W. Standards for the diagnosis and treatment of patients with COPD: a summary of the ATS/ERS position paper. Eur. Respir. J. 23, 932-946 (2004).
-
(2004)
Eur. Respir. J.
, vol.23
, pp. 932-946
-
-
Celli, B.R.1
MacNee, W.2
-
93
-
-
29244472009
-
Physician and patient perceptions in COPD: The COPD Resource Network Needs Assessment Survey
-
Barr, R. G. et al. Physician and patient perceptions in COPD: the COPD Resource Network Needs Assessment Survey. Am. J. Med. 118, 1415 (2005).
-
(2005)
Am. J. Med.
, vol.118
, pp. 1415
-
-
Barr, R.G.1
-
94
-
-
59349083538
-
Diagnosis and treatment considerations for women with COPD
-
Cote, C. G. & Chapman, K. R. Diagnosis and treatment considerations for women with COPD. Int. J. Clin. Pract. 63, 486-493 (2009).
-
(2009)
Int. J. Clin. Pract.
, vol.63
, pp. 486-493
-
-
Cote, C.G.1
Chapman, K.R.2
-
95
-
-
0345701470
-
Not 15 but 50% of smokers develop COPD? - Report from the Obstructive Lung Disease in Northern Sweden studies
-
Lundback, B. et al. Not 15 but 50% of smokers develop COPD? - Report from the Obstructive Lung Disease in Northern Sweden studies. Respir. Med. 97, 115-122 (2003).
-
(2003)
Respir. Med.
, vol.97
, pp. 115-122
-
-
Lundback, B.1
-
96
-
-
78349241777
-
Wood smoke exposure and gene promoter methylation are associated with increased risk for COPD in smokers
-
Sood, A. et al. Wood smoke exposure and gene promoter methylation are associated with increased risk for COPD in smokers. Am. J. Respir. Crit. Care Med. 182, 1098-1104 (2010).
-
(2010)
Am. J. Respir. Crit. Care Med.
, vol.182
, pp. 1098-1104
-
-
Sood, A.1
-
97
-
-
29244487415
-
Airway obstruction in never smokers: Results from the Third National Health and Nutrition Examination Survey
-
Celli, B. R., Halbert, R. J., Nordyke, R. J. & Schau, B. Airway obstruction in never smokers: results from the Third National Health and Nutrition Examination Survey. Am. J. Med. 118, 1364-1372 (2005).
-
(2005)
Am. J. Med.
, vol.118
, pp. 1364-1372
-
-
Celli, B.R.1
Halbert, R.J.2
Nordyke, R.J.3
Schau, B.4
-
98
-
-
34548262715
-
Poor airway function in early infancy and lung function by age 22 years: A non-selective longitudinal cohort study
-
Stern, D. A., Morgan, W. J., Wright, A. L., Guerra, S. & Martinez, F. D. Poor airway function in early infancy and lung function by age 22 years: a non-selective longitudinal cohort study. Lancet 370, 758-764 (2007).
-
(2007)
Lancet
, vol.370
, pp. 758-764
-
-
Stern, D.A.1
Morgan, W.J.2
Wright, A.L.3
Guerra, S.4
Martinez, F.D.5
-
99
-
-
84905669476
-
Disease progression in young patients with COPD: Rethinking the Fletcher and Peto model
-
Sanchez-Salcedo, P. et al. Disease progression in young patients with COPD: rethinking the Fletcher and Peto model. Eur. Respir. J. 44, 324-331 (2014).
-
(2014)
Eur. Respir. J.
, vol.44
, pp. 324-331
-
-
Sanchez-Salcedo, P.1
-
100
-
-
79952063902
-
Analysis of the lung microbiome in the "healthy" smoker and in COPD
-
Erb-Downward, J. R. et al. Analysis of the lung microbiome in the "healthy" smoker and in COPD. PLoS ONE 6, e16384 (2011).
-
(2011)
PLoS ONE
, vol.6
-
-
Erb-Downward, J.R.1
-
101
-
-
77953389042
-
Clinical COPD phenotypes: A novel approach using principal component and cluster analyses
-
Burgel, P. R. et al. Clinical COPD phenotypes: a novel approach using principal component and cluster analyses. Eur. Respir. J. 36, 531-539 (2012).
-
(2012)
Eur. Respir. J.
, vol.36
, pp. 531-539
-
-
Burgel, P.R.1
-
102
-
-
79954994400
-
Identification and prospective validation of clinically relevant chronic obstructive pulmonary disease (COPD) subtypes
-
Garcia-Aymerich, J. et al. Identification and prospective validation of clinically relevant chronic obstructive pulmonary disease (COPD) subtypes. Thorax 66, 430-437 (2011).
-
(2011)
Thorax
, vol.66
, pp. 430-437
-
-
Garcia-Aymerich, J.1
-
103
-
-
84964298566
-
Identification of five chronic obstructive pulmonary disease subgroups with different prognoses in the ECLIPSE cohort using cluster analysis
-
Rennard, S. et al. Identification of five chronic obstructive pulmonary disease subgroups with different prognoses in the ECLIPSE cohort using cluster analysis. Ann. Am. Thorac. Soc. 12, 303-312 (2014).
-
(2014)
Ann. Am. Thorac. Soc.
, vol.12
, pp. 303-312
-
-
Rennard, S.1
-
104
-
-
21744460289
-
Standardisation of spirometry
-
Miller, M. R. et al. Standardisation of spirometry. Eur. Respir. J. 26, 319-338 (2005).
-
(2005)
Eur. Respir. J.
, vol.26
, pp. 319-338
-
-
Miller, M.R.1
-
105
-
-
57149092192
-
Using the lower limit of normal for the FEV1/FVC ratio reduces the misclassification of airway obstruction
-
Swanney, M. P. et al. Using the lower limit of normal for the FEV1/FVC ratio reduces the misclassification of airway obstruction. Thorax 63, 1046-1051 (2008).
-
(2008)
Thorax
, vol.63
, pp. 1046-1051
-
-
Swanney, M.P.1
-
106
-
-
0032926069
-
Spirometric reference values from a sample of the general U. S. Population
-
Hankinson, J. L., Odencrantz, J. R. & Fedan, K. B. Spirometric reference values from a sample of the general U. S. population. Am. J. Respir. Crit. Care Med. 159, 179-187 (1999).
-
(1999)
Am. J. Respir. Crit. Care Med.
, vol.159
, pp. 179-187
-
-
Hankinson, J.L.1
Odencrantz, J.R.2
Fedan, K.B.3
-
107
-
-
1442306237
-
The body-mass index, airflow obstruction, dyspnea, and exercise capacity index in chronic obstructive pulmonary disease
-
Celli, B. R. et al. The body-mass index, airflow obstruction, dyspnea, and exercise capacity index in chronic obstructive pulmonary disease. N. Engl. J. Med. 350, 1005-1012 (2004).
-
(2004)
N. Engl. J. Med.
, vol.350
, pp. 1005-1012
-
-
Celli, B.R.1
-
108
-
-
84916244647
-
An official European Respiratory Society statement on physical activity in COPD
-
Watz, H. et al. An official European Respiratory Society statement on physical activity in COPD. Eur. Respir. J. 44, 1521-1537 (2014).
-
(2014)
Eur. Respir. J.
, vol.44
, pp. 1521-1537
-
-
Watz, H.1
-
110
-
-
84899872379
-
An official American Thoracic Society/ European Respiratory Society statement: Update on limb muscle dysfunction in chronic obstructive pulmonary disease
-
Maltais, F. et al. An official American Thoracic Society/ European Respiratory Society statement: update on limb muscle dysfunction in chronic obstructive pulmonary disease. Am. J. Respir. Crit. Care Med. 189, e15-e62 (2014).
-
(2014)
Am. J. Respir. Crit. Care Med.
, vol.189
, pp. e15-e62
-
-
Maltais, F.1
-
111
-
-
69149083159
-
Expansion of the prognostic assessment of patients with chronic obstructive pulmonary disease: The updated BODE index and the ADO index
-
Puhan, M. A. et al. Expansion of the prognostic assessment of patients with chronic obstructive pulmonary disease: the updated BODE index and the ADO index. Lancet 374, 704-711 (2009).
-
(2009)
Lancet
, vol.374
, pp. 704-711
-
-
Puhan, M.A.1
-
112
-
-
72549113283
-
Derivation and validation of a composite index of severity in chronic obstructive pulmonary disease: The DOSE index
-
Jones, R. C. et al. Derivation and validation of a composite index of severity in chronic obstructive pulmonary disease: the DOSE index. Am. J. Respir. Crit. Care Med. 180, 1189-1195 (2009).
-
(2009)
Am. J. Respir. Crit. Care Med.
, vol.180
, pp. 1189-1195
-
-
Jones, R.C.1
-
113
-
-
84882626475
-
Multicomponent indices to predict survival in COPD: The COCOMICS study
-
Marin, J. M. et al. Multicomponent indices to predict survival in COPD: the COCOMICS study. Eur. Respir. J. 42, 323-332 (2013).
-
(2013)
Eur. Respir. J.
, vol.42
, pp. 323-332
-
-
Marin, J.M.1
-
114
-
-
84863952703
-
Comorbidities and risk of mortality in patients with chronic obstructive pulmonary disease
-
Divo, M. et al. Comorbidities and risk of mortality in patients with chronic obstructive pulmonary disease. Am. J. Respir. Crit. Care Med. 186, 155-161 (2012).
-
(2012)
Am. J. Respir. Crit. Care Med.
, vol.186
, pp. 155-161
-
-
Divo, M.1
-
115
-
-
79955578132
-
Quantifying the extent of emphysema: Factors associated with radiologists' estimations and quantitative indices of emphysema severity using the ECLIPSE cohort
-
Gietema, H. A. et al. Quantifying the extent of emphysema: factors associated with radiologists' estimations and quantitative indices of emphysema severity using the ECLIPSE cohort. Acad. Radiol. 18, 661-671 (2011).
-
(2011)
Acad. Radiol.
, vol.18
, pp. 661-671
-
-
Gietema, H.A.1
-
116
-
-
80054690890
-
Lung cancer in patients with chronic obstructive pulmonary disease - Incidence and predicting factors
-
de Torres, J. P. et al. Lung cancer in patients with chronic obstructive pulmonary disease - incidence and predicting factors. Am. J. Respir. Crit. Care Med. 184, 913-919 (2011).
-
(2011)
Am. J. Respir. Crit. Care Med.
, vol.184
, pp. 913-919
-
-
De Torres, J.P.1
-
117
-
-
80053350305
-
Changes in forced expiratory volume in 1 second over time in COPD
-
Vestbo, J. et al. Changes in forced expiratory volume in 1 second over time in COPD. N. Engl. J. Med. 365, 1184-1192 (2011).
-
(2011)
N. Engl. J. Med.
, vol.365
, pp. 1184-1192
-
-
Vestbo, J.1
-
118
-
-
33745445884
-
Pulmonary biomarkers in chronic obstructive pulmonary disease
-
Barnes, P. J. et al. Pulmonary biomarkers in chronic obstructive pulmonary disease. Am. J. Respir. Crit. Care Med. 174, 6-14 (2006).
-
(2006)
Am. J. Respir. Crit. Care Med.
, vol.174
, pp. 6-14
-
-
Barnes, P.J.1
-
119
-
-
84873109994
-
The role of systemic inflammatory biomarkers to predict mortality in chronic obstructive pulmonary disease
-
Kelly, E., Owen, C. A., Pinto-Plata, V. & Celli, B. R. The role of systemic inflammatory biomarkers to predict mortality in chronic obstructive pulmonary disease. Expert Rev. Respir. Med. 7, 57-64 (2013).
-
(2013)
Expert Rev. Respir. Med.
, vol.7
, pp. 57-64
-
-
Kelly, E.1
Owen, C.A.2
Pinto-Plata, V.3
Celli, B.R.4
-
120
-
-
84878642324
-
The presence and progression of emphysema in COPD as determined by CT scanning and biomarker expression: A prospective analysis from the ECLIPSE study
-
Coxson, H. O. et al. The presence and progression of emphysema in COPD as determined by CT scanning and biomarker expression: a prospective analysis from the ECLIPSE study. Lancet Respir. Med. 1, 129-136 (2013).
-
(2013)
Lancet Respir. Med.
, vol.1
, pp. 129-136
-
-
Coxson, H.O.1
-
121
-
-
34447331959
-
Profiling serum biomarkers in patients with COPD: Associations with clinical parameters
-
Pinto-Plata, V. et al. Profiling serum biomarkers in patients with COPD: associations with clinical parameters. Thorax 62, 595-601 (2007).
-
(2007)
Thorax
, vol.62
, pp. 595-601
-
-
Pinto-Plata, V.1
-
122
-
-
79961046696
-
Diagnosis and management of stable chronic obstructive pulmonary disease: A clinical practice guideline update from the American College of Physicians, American College of Chest Physicians, American Thoracic Society, and European Respiratory Society
-
Qaseem, A. et al. Diagnosis and management of stable chronic obstructive pulmonary disease: a clinical practice guideline update from the American College of Physicians, American College of Chest Physicians, American Thoracic Society, and European Respiratory Society. Ann. Intern. Med. 155, 179-191 (2011).
-
(2011)
Ann. Intern. Med.
, vol.155
, pp. 179-191
-
-
Qaseem, A.1
-
123
-
-
34247112793
-
Tobacco tightrope - Balancing disease prevention and economic development in China
-
Wright, A. A. & Katz, I. T. Tobacco tightrope - balancing disease prevention and economic development in China. N. Engl. J. Med. 356, 1493-1496 (2007).
-
(2007)
N. Engl. J. Med.
, vol.356
, pp. 1493-1496
-
-
Wright, A.A.1
Katz, I.T.2
-
124
-
-
84891932828
-
Smoking prevalence and cigarette consumption in 187 countries, 1980-2012
-
Ng, M. et al. Smoking prevalence and cigarette consumption in 187 countries, 1980-2012. JAMA 311, 183-192 (2014).
-
(2014)
JAMA
, vol.311
, pp. 183-192
-
-
Ng, M.1
-
125
-
-
84910079668
-
A systematic review of health effects of electronic cigarettes
-
Pisinger, C. & Dossing, M. A systematic review of health effects of electronic cigarettes. Prev. Med. 69, 248-260 (2014).
-
(2014)
Prev. Med.
, vol.69
, pp. 248-260
-
-
Pisinger, C.1
Dossing, M.2
-
126
-
-
84892464234
-
Adherence to reduced-polluting biomass fuel stoves improves respiratory and sleep symptoms in children
-
Accinelli, R. A. et al. Adherence to reduced-polluting biomass fuel stoves improves respiratory and sleep symptoms in children. BMC Pediatr. 14, 12 (2014).
-
(2014)
BMC Pediatr.
, vol.14
, pp. 12
-
-
Accinelli, R.A.1
-
127
-
-
72549116822
-
Adherence to inhaled therapy, mortality and hospital admission in COPD
-
Vestbo, J. et al. Adherence to inhaled therapy, mortality and hospital admission in COPD. Thorax 64, 939-943 (2009).
-
(2009)
Thorax
, vol.64
, pp. 939-943
-
-
Vestbo, J.1
-
128
-
-
84865130942
-
Can patients with COPD self-manage?
-
Wedzicha, J. A. & Vestbo, J. Can patients with COPD self-manage? Lancet 380, 624-625 (2012).
-
(2012)
Lancet
, vol.380
, pp. 624-625
-
-
Wedzicha, J.A.1
Vestbo, J.2
-
129
-
-
84857942044
-
Piloting tele-monitoring in COPD: A mixed methods exploration of issues in design and implementation
-
Ure, J. et al. Piloting tele-monitoring in COPD: a mixed methods exploration of issues in design and implementation. Prim. Care Respir. J. 21, 57-64 (2012).
-
(2012)
Prim. Care Respir. J.
, vol.21
, pp. 57-64
-
-
Ure, J.1
-
130
-
-
84877126115
-
Once-daily inhaled fluticasone furoate and vilanterol versus vilanterol only for prevention of exacerbations of COPD: Two replicate double-blind, parallel-group, randomised controlled trials
-
Dransfield, M. T. et al. Once-daily inhaled fluticasone furoate and vilanterol versus vilanterol only for prevention of exacerbations of COPD: two replicate double-blind, parallel-group, randomised controlled trials. Lancet Respir. Med. 1, 210-223 (2013).
-
(2013)
Lancet Respir. Med.
, vol.1
, pp. 210-223
-
-
Dransfield, M.T.1
-
131
-
-
77956084309
-
Management of stable chronic obstructive pulmonary disease in primary and secondary care: Summary of updated NICE guidance
-
O'Reilly, J., Jones, M. M., Parnham, J., Lovibond, K. & Rudolf, M. Management of stable chronic obstructive pulmonary disease in primary and secondary care: summary of updated NICE guidance. BMJ 340, c3134 (2010).
-
(2010)
BMJ
, vol.340
, pp. c3134
-
-
O'Reilly, J.1
Jones, M.M.2
Parnham, J.3
Lovibond, K.4
Rudolf, M.5
-
132
-
-
63249124498
-
Pulmonary rehabilitation for management of chronic obstructive pulmonary disease
-
Casaburi, R. & ZuWallack, R. Pulmonary rehabilitation for management of chronic obstructive pulmonary disease. N. Engl. J. Med. 360, 1329-1335 (2009).
-
(2009)
N. Engl. J. Med.
, vol.360
, pp. 1329-1335
-
-
Casaburi, R.1
ZuWallack, R.2
-
133
-
-
84881508308
-
British Thoracic Society guideline on pulmonary rehabilitation in adults
-
Bolton, C. E. et al. British Thoracic Society guideline on pulmonary rehabilitation in adults. Thorax 68 (Suppl. 2), ii1-ii30 (2013).
-
(2013)
Thorax
, vol.68
, pp. ii1-ii30
-
-
Bolton, C.E.1
-
134
-
-
84886418056
-
An official American Thoracic Society/European Respiratory Society statement: Key concepts and advances in pulmonary rehabilitation
-
Spruit, M. A. et al. An official American Thoracic Society/European Respiratory Society statement: key concepts and advances in pulmonary rehabilitation. Am. J. Respir. Crit. Care Med. 188, e13-e64 (2013).
-
(2013)
Am. J. Respir. Crit. Care Med.
, vol.188
, pp. e13-e64
-
-
Spruit, M.A.1
-
135
-
-
24644518890
-
Physiological changes during symptom recovery from moderate exacerbations of COPD
-
Parker, C. M., Voduc, N., Aaron, S. D., Webb, K. A. & O'Donnell, D. E. Physiological changes during symptom recovery from moderate exacerbations of COPD. Eur. Respir. J. 26, 420-428 (2005).
-
(2005)
Eur. Respir. J.
, vol.26
, pp. 420-428
-
-
Parker, C.M.1
Voduc, N.2
Aaron, S.D.3
Webb, K.A.4
O'Donnell, D.E.5
-
136
-
-
77956052751
-
Cardiovascular events in patients with COPD: TORCH study results
-
Calverley, P. M. et al. Cardiovascular events in patients with COPD: TORCH study results. Thorax 65, 719-725 (2010).
-
(2010)
Thorax
, vol.65
, pp. 719-725
-
-
Calverley, P.M.1
-
137
-
-
53749102775
-
A 4-year trial of tiotropium in chronic obstructive pulmonary disease
-
Tashkin, D. P. et al. A 4-year trial of tiotropium in chronic obstructive pulmonary disease. N. Engl. J. Med. 359, 1543-1554 (2008).
-
(2008)
N. Engl. J. Med.
, vol.359
, pp. 1543-1554
-
-
Tashkin, D.P.1
-
138
-
-
84885734407
-
Tiotropium Respimat inhaler and the risk of death in COPD
-
Wise, R. A. et al. Tiotropium Respimat inhaler and the risk of death in COPD. N. Engl. J. Med. 369, 1491-1501 (2013).
-
(2013)
N. Engl. J. Med.
, vol.369
, pp. 1491-1501
-
-
Wise, R.A.1
-
139
-
-
84928384173
-
New combination bronchodilators for COPD: Current evidence and future perspectives
-
Singh, D. New combination bronchodilators for COPD: current evidence and future perspectives. Br. J. Clin. Pharmacol. 79, 695-708 (2015).
-
(2015)
Br. J. Clin. Pharmacol.
, vol.79
, pp. 695-708
-
-
Singh, D.1
-
140
-
-
33847172367
-
Salmeterol and fluticasone propionate and survival in chronic obstructive pulmonary disease
-
Calverley, P. M. et al. Salmeterol and fluticasone propionate and survival in chronic obstructive pulmonary disease. N. Engl. J. Med. 356, 775-789 (2007).
-
(2007)
N. Engl. J. Med.
, vol.356
, pp. 775-789
-
-
Calverley, P.M.1
-
141
-
-
84938538243
-
Novel endoscopic approaches to treating chronic obstructive pulmonary disease and emphysema
-
Gompelmann, D., Eberhardt, R. & Herth, F. J. Novel endoscopic approaches to treating chronic obstructive pulmonary disease and emphysema. Semin. Respir. Crit. Care Med. 36, 609-615 (2015).
-
(2015)
Semin. Respir. Crit. Care Med.
, vol.36
, pp. 609-615
-
-
Gompelmann, D.1
Eberhardt, R.2
Herth, F.J.3
-
142
-
-
0033773356
-
Detection of rhinoviruses in induced sputum at exacerbations of chronic obstructive pulmonary disease
-
Seemungal, T., Harper-Owen, R., Bhowmik, A., Jeffries, D. J. & Wedzicha, J. A. Detection of rhinoviruses in induced sputum at exacerbations of chronic obstructive pulmonary disease. Eur. Respir. J. 16, 677-683 (2000).
-
(2000)
Eur. Respir. J.
, vol.16
, pp. 677-683
-
-
Seemungal, T.1
Harper-Owen, R.2
Bhowmik, A.3
Jeffries, D.J.4
Wedzicha, J.A.5
-
143
-
-
3442890263
-
Early therapy improves outcomes of exacerbations of chronic obstructive pulmonary disease
-
Wilkinson, T. M., Donaldson, G. C., Hurst, J. R., Seemungal, T. A. & Wedzicha, J. A. Early therapy improves outcomes of exacerbations of chronic obstructive pulmonary disease. Am. J. Respir. Crit. Care Med. 169, 1298-1303 (2004).
-
(2004)
Am. J. Respir. Crit. Care Med.
, vol.169
, pp. 1298-1303
-
-
Wilkinson, T.M.1
Donaldson, G.C.2
Hurst, J.R.3
Seemungal, T.A.4
Wedzicha, J.A.5
-
144
-
-
0036794862
-
Relationship between exacerbation frequency and lung function decline in chronic obstructive pulmonary disease
-
Donaldson, G. C., Seemungal, T. A., Bhowmik, A. & Wedzicha, J. A. Relationship between exacerbation frequency and lung function decline in chronic obstructive pulmonary disease. Thorax 57, 847-852 (2002).
-
(2002)
Thorax
, vol.57
, pp. 847-852
-
-
Donaldson, G.C.1
Seemungal, T.A.2
Bhowmik, A.3
Wedzicha, J.A.4
-
145
-
-
0035422691
-
Lower respiratory illnesses promote FEV1 decline in current smokers but not ex-smokers with mild chronic obstructive pulmonary disease: Results from the lung health study
-
Kanner, R. E., Anthonisen, N. R. & Connett, J. E. Lower respiratory illnesses promote FEV1 decline in current smokers but not ex-smokers with mild chronic obstructive pulmonary disease: results from the lung health study. Am. J. Respir. Crit. Care Med. 164, 358-364 (2001).
-
(2001)
Am. J. Respir. Crit. Care Med.
, vol.164
, pp. 358-364
-
-
Kanner, R.E.1
Anthonisen, N.R.2
Connett, J.E.3
-
146
-
-
77951803863
-
Increased risk of myocardial infarction and stroke following exacerbation of COPD
-
Donaldson, G. C., Hurst, J. R., Smith, C. J., Hubbard, R. B. & Wedzicha, J. A. Increased risk of myocardial infarction and stroke following exacerbation of COPD. Chest 137, 1091-1097 (2010).
-
(2010)
Chest
, vol.137
, pp. 1091-1097
-
-
Donaldson, G.C.1
Hurst, J.R.2
Smith, C.J.3
Hubbard, R.B.4
Wedzicha, J.A.5
-
147
-
-
84860483262
-
Diagnosis of myocardial infarction following hospitalisation for exacerbation of COPD
-
McAllister, D. A. et al. Diagnosis of myocardial infarction following hospitalisation for exacerbation of COPD. Eur. Respir. J. 39, 1097-1103 (2012).
-
(2012)
Eur. Respir. J.
, vol.39
, pp. 1097-1103
-
-
McAllister, D.A.1
-
148
-
-
0023164742
-
Antibiotic therapy in exacerbations of chronic obstructive pulmonary disease
-
Anthonisen, N. R. et al. Antibiotic therapy in exacerbations of chronic obstructive pulmonary disease. Ann. Intern. Med. 106, 196-204 (1987).
-
(1987)
Ann. Intern. Med.
, vol.106
, pp. 196-204
-
-
Anthonisen, N.R.1
-
149
-
-
84878538257
-
Short-term versus conventional glucocorticoid therapy in acute exacerbations of chronic obstructive pulmonary disease: The REDUCE randomized clinical trial
-
Leuppi, J. D. et al. Short-term versus conventional glucocorticoid therapy in acute exacerbations of chronic obstructive pulmonary disease: the REDUCE randomized clinical trial. JAMA 309, 2223-2231 (2013).
-
(2013)
JAMA
, vol.309
, pp. 2223-2231
-
-
Leuppi, J.D.1
-
150
-
-
84863447204
-
Blood eosinophils to direct corticosteroid treatment of exacerbations of chronic obstructive pulmonary disease: A randomized placebo-controlled trial
-
Bafadhel, M. et al. Blood eosinophils to direct corticosteroid treatment of exacerbations of chronic obstructive pulmonary disease: a randomized placebo-controlled trial. Am. J. Respir. Crit. Care Med. 186, 48-55 (2012).
-
(2012)
Am. J. Respir. Crit. Care Med.
, vol.186
, pp. 48-55
-
-
Bafadhel, M.1
-
151
-
-
34948849855
-
Effectiveness of influenza vaccine in the community-dwelling elderly
-
Nichol, K. L., Nordin, J. D., Nelson, D. B., Mullooly, J. P. & Hak, E. Effectiveness of influenza vaccine in the community-dwelling elderly. N. Engl. J. Med. 357, 1373-1381 (2007).
-
(2007)
N. Engl. J. Med.
, vol.357
, pp. 1373-1381
-
-
Nichol, K.L.1
Nordin, J.D.2
Nelson, D.B.3
Mullooly, J.P.4
Hak, E.5
-
152
-
-
84899470468
-
Long-acting beta2-agonists for chronic obstructive pulmonary disease
-
Kew, K. M., Mavergames, C. & Walters, J. A. Long-acting beta2-agonists for chronic obstructive pulmonary disease. Cochrane Database Syst. Rev. 10, CD010177 (2013).
-
(2013)
Cochrane Database Syst. Rev.
, vol.10
, pp. CD010177
-
-
Kew, K.M.1
Mavergames, C.2
Walters, J.A.3
-
153
-
-
84922395042
-
Tiotropium versus placebo for chronic obstructive pulmonary disease
-
Karner, C., Chong, J. & Poole, P. Tiotropium versus placebo for chronic obstructive pulmonary disease. Cochrane Database Syst. Rev. 7, CD009285 (2014).
-
(2014)
Cochrane Database Syst. Rev.
, vol.7
, pp. CD009285
-
-
Karner, C.1
Chong, J.2
Poole, P.3
-
154
-
-
84930866341
-
Blood eosinophil counts, exacerbations, and response to the addition of inhaled fluticasone furoate to vilanterol in patients with chronic obstructive pulmonary disease: A secondary analysis of data from two parallel randomised controlled trials
-
Pascoe, S., Locantore, N., Dransfield, M. T., Barnes, N. C. & Pavord, I. D. Blood eosinophil counts, exacerbations, and response to the addition of inhaled fluticasone furoate to vilanterol in patients with chronic obstructive pulmonary disease: a secondary analysis of data from two parallel randomised controlled trials. Lancet Respir. Med. 3, 435-442 (2015).
-
(2015)
Lancet Respir. Med.
, vol.3
, pp. 435-442
-
-
Pascoe, S.1
Locantore, N.2
Dransfield, M.T.3
Barnes, N.C.4
Pavord, I.D.5
-
155
-
-
84939433292
-
Blood eosinophils: A biomarker of response to extrafine beclomethasone/formoterol in chronic obstructive pulmonary disease
-
Siddiqui, S. H. et al. Blood eosinophils: a biomarker of response to extrafine beclomethasone/formoterol in chronic obstructive pulmonary disease. Am. J. Respir. Crit. Care Med. 192, 523-525 (2015).
-
(2015)
Am. J. Respir. Crit. Care Med.
, vol.192
, pp. 523-525
-
-
Siddiqui, S.H.1
-
156
-
-
84921395714
-
Incident pneumonia and mortality in patients with chronic obstructive pulmonary disease. A double effect of inhaled corticosteroids?
-
Festic, E. & Scanlon, P. D. Incident pneumonia and mortality in patients with chronic obstructive pulmonary disease. A double effect of inhaled corticosteroids? Am. J. Respir. Crit. Care Med. 191, 141-148 (2015).
-
(2015)
Am. J. Respir. Crit. Care Med.
, vol.191
, pp. 141-148
-
-
Festic, E.1
Scanlon, P.D.2
-
157
-
-
79953166862
-
Tiotropium versus salmeterol for the prevention of exacerbations of COPD
-
Vogelmeier, C. et al. Tiotropium versus salmeterol for the prevention of exacerbations of COPD. N. Engl. J. Med. 364, 1093-1103 (2011).
-
(2011)
N. Engl. J. Med.
, vol.364
, pp. 1093-1103
-
-
Vogelmeier, C.1
-
158
-
-
37849011194
-
The prevention of chronic obstructive pulmonary disease exacerbations by salmeterol/fluticasone propionate or tiotropium bromide
-
Wedzicha, J. A. et al. The prevention of chronic obstructive pulmonary disease exacerbations by salmeterol/fluticasone propionate or tiotropium bromide. Am. J. Respir. Crit. Care Med. 177, 19-26 (2008).
-
(2008)
Am. J. Respir. Crit. Care Med.
, vol.177
, pp. 19-26
-
-
Wedzicha, J.A.1
-
159
-
-
84877131237
-
Analysis of chronic obstructive pulmonary disease exacerbations with the dual bronchodilator QVA149 compared with glycopyrronium and tiotropium (SPARK): A randomised, double-blind, parallel-group study
-
Wedzicha, J. A. et al. Analysis of chronic obstructive pulmonary disease exacerbations with the dual bronchodilator QVA149 compared with glycopyrronium and tiotropium (SPARK): a randomised, double-blind, parallel-group study. Lancet Respir. Med. 1, 199-209 (2013).
-
(2013)
Lancet Respir. Med.
, vol.1
, pp. 199-209
-
-
Wedzicha, J.A.1
-
160
-
-
69149103642
-
Roflumilast in symptomatic chronic obstructive pulmonary disease: Two randomised clinical trials
-
Calverley, P. M. et al. Roflumilast in symptomatic chronic obstructive pulmonary disease: two randomised clinical trials. Lancet 374, 685-694 (2009).
-
(2009)
Lancet
, vol.374
, pp. 685-694
-
-
Calverley, P.M.1
-
161
-
-
84924250308
-
Effect of roflumilast on exacerbations in patients with severe chronic obstructive pulmonary disease uncontrolled by combination therapy (REACT): A multicentre randomised controlled trial
-
Martinez, F. J. et al. Effect of roflumilast on exacerbations in patients with severe chronic obstructive pulmonary disease uncontrolled by combination therapy (REACT): a multicentre randomised controlled trial. Lancet 385, 857-866 (2015).
-
(2015)
Lancet
, vol.385
, pp. 857-866
-
-
Martinez, F.J.1
-
162
-
-
56749157688
-
Long-term erythromycin therapy is associated with decreased chronic obstructive pulmonary disease exacerbations
-
Seemungal, T. A. et al. Long-term erythromycin therapy is associated with decreased chronic obstructive pulmonary disease exacerbations. Am. J. Respir. Crit. Care Med. 178, 1139-1147 (2008).
-
(2008)
Am. J. Respir. Crit. Care Med.
, vol.178
, pp. 1139-1147
-
-
Seemungal, T.A.1
-
163
-
-
80052157895
-
Azithromycin for prevention of exacerbations of COPD
-
Albert, R. K. et al. Azithromycin for prevention of exacerbations of COPD. N. Engl. J. Med. 365, 689-698 (2011).
-
(2011)
N. Engl. J. Med.
, vol.365
, pp. 689-698
-
-
Albert, R.K.1
-
164
-
-
84877120597
-
Risks of population antimicrobial resistance associated with chronic macrolide use for inflammatory airway diseases
-
Serisier, D. J. Risks of population antimicrobial resistance associated with chronic macrolide use for inflammatory airway diseases. Lancet Respir. Med. 1, 262-274 (2013).
-
(2013)
Lancet Respir. Med.
, vol.1
, pp. 262-274
-
-
Serisier, D.J.1
-
165
-
-
44849100529
-
Effect of carbocisteine on acute exacerbation of chronic obstructive pulmonary disease (PEACE study): A randomised placebo-controlled study
-
Zheng, J. P. et al. Effect of carbocisteine on acute exacerbation of chronic obstructive pulmonary disease (PEACE study): a randomised placebo-controlled study. Lancet 371, 2013-2018 (2008).
-
(2008)
Lancet
, vol.371
, pp. 2013-2018
-
-
Zheng, J.P.1
-
166
-
-
84895803870
-
Twice daily N-acetylcysteine 600 mg for exacerbations of chronic obstructive pulmonary disease (PANTHEON): A randomised, double-blind placebo-controlled trial
-
Zheng, J. P. et al. Twice daily N-acetylcysteine 600 mg for exacerbations of chronic obstructive pulmonary disease (PANTHEON): a randomised, double-blind placebo-controlled trial. Lancet Respir. Med. 2, 187-194 (2014).
-
(2014)
Lancet Respir. Med.
, vol.2
, pp. 187-194
-
-
Zheng, J.P.1
-
167
-
-
61349194438
-
Does early pulmonary rehabilitation reduce acute health-care utilization in COPD patients admitted with an exacerbation? A randomized controlled study
-
Eaton, T. et al. Does early pulmonary rehabilitation reduce acute health-care utilization in COPD patients admitted with an exacerbation? A randomized controlled study. Respirology 14, 230-238 (2009).
-
(2009)
Respirology
, vol.14
, pp. 230-238
-
-
Eaton, T.1
-
168
-
-
84903977648
-
An early rehabilitation intervention to enhance recovery during hospital admission for an exacerbation of chronic respiratory disease: Randomised controlled trial
-
Greening, N. J. et al. An early rehabilitation intervention to enhance recovery during hospital admission for an exacerbation of chronic respiratory disease: randomised controlled trial. BMJ 349, g4315 (2014).
-
(2014)
BMJ
, vol.349
, pp. g4315
-
-
Greening, N.J.1
-
169
-
-
0038440780
-
The assessment of health status among patients with COPD
-
Curtis, J. R. & Patrick, D. L. The assessment of health status among patients with COPD. Eur. Respir. J. Suppl. 41, 36s-45s (2003).
-
(2003)
Eur. Respir. J. Suppl.
, vol.41
, pp. 36s-45s
-
-
Curtis, J.R.1
Patrick, D.L.2
-
170
-
-
78649928314
-
Health-related quality of life in patients by COPD severity within primary care in Europe
-
Jones, P. W. et al. Health-related quality of life in patients by COPD severity within primary care in Europe. Respir. Med. 105, 57-66 (2011).
-
(2011)
Respir. Med.
, vol.105
, pp. 57-66
-
-
Jones, P.W.1
-
171
-
-
84884813850
-
Factors associated with changes in quality of life of COPD patients: A prospective study in primary care
-
Monteagudo, M. et al. Factors associated with changes in quality of life of COPD patients: a prospective study in primary care. Respir. Med. 107, 1589-1597 (2013).
-
(2013)
Respir. Med.
, vol.107
, pp. 1589-1597
-
-
Monteagudo, M.1
-
172
-
-
84865302702
-
Determinants of polypharmacy and compliance with GOLD guidelines in patients with chronic obstructive pulmonary disease
-
Franssen, F. M., Spruit, M. A. & Wouters, E. F. Determinants of polypharmacy and compliance with GOLD guidelines in patients with chronic obstructive pulmonary disease. Int. J. Chron. Obstruct. Pulmon. Dis. 6, 493-501 (2011).
-
(2011)
Int. J. Chron. Obstruct. Pulmon. Dis.
, vol.6
, pp. 493-501
-
-
Franssen, F.M.1
Spruit, M.A.2
Wouters, E.F.3
-
173
-
-
77955182204
-
Relation between quality of life and morbidity and mortality in COPD patients: Two-year follow-up study
-
Yorgancioglu, A., Havlucu, Y., Celik, P., Dinc, G. & Saka, A. Relation between quality of life and morbidity and mortality in COPD patients: two-year follow-up study. COPD 7, 248-253 (2010).
-
(2010)
COPD
, vol.7
, pp. 248-253
-
-
Yorgancioglu, A.1
Havlucu, Y.2
Celik, P.3
Dinc, G.4
Saka, A.5
-
174
-
-
0036724330
-
Health-related quality of life and mortality in male patients with chronic obstructive pulmonary disease
-
Domingo-Salvany, A. et al. Health-related quality of life and mortality in male patients with chronic obstructive pulmonary disease. Am. J. Respir. Crit. Care Med. 166, 680-685 (2002).
-
(2002)
Am. J. Respir. Crit. Care Med.
, vol.166
, pp. 680-685
-
-
Domingo-Salvany, A.1
-
175
-
-
0034777617
-
Health status measurement in chronic obstructive pulmonary disease
-
Jones, P. W. Health status measurement in chronic obstructive pulmonary disease. Thorax 56, 880-887 (2001).
-
(2001)
Thorax
, vol.56
, pp. 880-887
-
-
Jones, P.W.1
-
176
-
-
84875847989
-
Clusters of comorbidities based on validated objective measurements and systemic inflammation in patients with chronic obstructive pulmonary disease
-
Vanfleteren, L. E. et al. Clusters of comorbidities based on validated objective measurements and systemic inflammation in patients with chronic obstructive pulmonary disease. Am. J. Respir. Crit. Care Med. 187, 728-735 (2013).
-
(2013)
Am. J. Respir. Crit. Care Med.
, vol.187
, pp. 728-735
-
-
Vanfleteren, L.E.1
-
177
-
-
84878498314
-
Impact of co-morbidities on self-rated health in self-reported COPD: An analysis of NHANES 2001-2008
-
Putcha, N., Puhan, M. A., Hansel, N. N., Drummond, M. B. & Boyd, C. M. Impact of co-morbidities on self-rated health in self-reported COPD: an analysis of NHANES 2001-2008. COPD 10, 324-332 (2013).
-
(2013)
COPD
, vol.10
, pp. 324-332
-
-
Putcha, N.1
Puhan, M.A.2
Hansel, N.N.3
Drummond, M.B.4
Boyd, C.M.5
-
178
-
-
84885109944
-
Cardiovascular comorbidity in COPD: Systematic literature review
-
Mullerova, H., Agusti, A., Erqou, S. & Mapel, D. W. Cardiovascular comorbidity in COPD: systematic literature review. Chest 144, 1163-1178 (2013).
-
(2013)
Chest
, vol.144
, pp. 1163-1178
-
-
Mullerova, H.1
Agusti, A.2
Erqou, S.3
Mapel, D.W.4
-
179
-
-
84855405460
-
Unrecognised ventricular dysfunction in COPD
-
Macchia, A. et al. Unrecognised ventricular dysfunction in COPD. Eur. Respir. J. 39, 51-58 (2012).
-
(2012)
Eur. Respir. J.
, vol.39
, pp. 51-58
-
-
Macchia, A.1
-
180
-
-
55249090655
-
Anxiety and depression in COPD: Current understanding, unanswered questions, and research needs
-
Maurer, J. et al. Anxiety and depression in COPD: current understanding, unanswered questions, and research needs. Chest 134, 43S-56S (2008).
-
(2008)
Chest
, vol.134
, pp. 43S-56S
-
-
Maurer, J.1
-
181
-
-
84884331422
-
Bidirectional associations between clinically relevant depression or anxiety and chronic obstructive pulmonary disease (COPD): A systematic review and meta-analysis
-
Atlantis, E., Fahey, P., Cochrane, B. & Smith, S. Bidirectional associations between clinically relevant depression or anxiety and chronic obstructive pulmonary disease (COPD): a systematic review and meta-analysis. Chest 144, 766-777 (2013).
-
(2013)
Chest
, vol.144
, pp. 766-777
-
-
Atlantis, E.1
Fahey, P.2
Cochrane, B.3
Smith, S.4
-
182
-
-
84907149383
-
Epidemiology and clinical impact of major comorbidities in patients with COPD
-
Smith, M. C. & Wrobel, J. P. Epidemiology and clinical impact of major comorbidities in patients with COPD. Int. J. Chron. Obstruct. Pulmon. Dis. 9, 871-888 (2014).
-
(2014)
Int. J. Chron. Obstruct. Pulmon. Dis.
, vol.9
, pp. 871-888
-
-
Smith, M.C.1
Wrobel, J.P.2
-
183
-
-
84961287979
-
COPD-bronchiectasis overlap syndrome
-
Hurst, J. R., Elborn, J. S. & De Soyza, A. COPD-bronchiectasis overlap syndrome. Eur. Respir. J. 45, 310-313 (2015).
-
(2015)
Eur. Respir. J.
, vol.45
, pp. 310-313
-
-
Hurst, J.R.1
Elborn, J.S.2
De Soyza, A.3
-
184
-
-
84875229819
-
Clinical phenotypes of chronic obstructive pulmonary disease and asthma: Recent advances
-
Carolan, B. J. & Sutherland, E. R. Clinical phenotypes of chronic obstructive pulmonary disease and asthma: recent advances. J. Allergy Clin. Immunol. 131, 627-634 (2013).
-
(2013)
J. Allergy Clin. Immunol.
, vol.131
, pp. 627-634
-
-
Carolan, B.J.1
Sutherland, E.R.2
-
185
-
-
84941028441
-
Therapeutic approaches to asthma-chronic obstructive pulmonary disease overlap syndromes
-
Barnes, P. J. Therapeutic approaches to asthma-chronic obstructive pulmonary disease overlap syndromes. J. Allergy Clin. Immunol. 136, 531-545 (2015).
-
(2015)
J. Allergy Clin. Immunol.
, vol.136
, pp. 531-545
-
-
Barnes, P.J.1
-
186
-
-
84978138746
-
Surfactant protein D, club cell protein 16, pulmonary and activation-regulated chemokine, C-reactive protein, and fibrinogen biomarker variation in chronic obstructive lung disease
-
Lock-Johansson, S., Vestbo, J. & Sorensen, G. Surfactant protein D, club cell protein 16, pulmonary and activation-regulated chemokine, C-reactive protein, and fibrinogen biomarker variation in chronic obstructive lung disease. Respir. Res. 15, 147 (2014).
-
(2014)
Respir. Res.
, vol.15
, pp. 147
-
-
Lock-Johansson, S.1
Vestbo, J.2
Sorensen, G.3
-
187
-
-
79956218469
-
Epigenetic control of gene expression in the lung
-
Yang, I. V. & Schwartz, D. A. Epigenetic control of gene expression in the lung. Am. J. Respir. Crit. Care Med. 183, 1295-1301 (2011).
-
(2011)
Am. J. Respir. Crit. Care Med.
, vol.183
, pp. 1295-1301
-
-
Yang, I.V.1
Schwartz, D.A.2
-
188
-
-
84879693217
-
New anti-inflammatory treatments for chronic obstructive pulmonary disease
-
Barnes, P. J. New anti-inflammatory treatments for chronic obstructive pulmonary disease. Nat. Rev. Drug Discov. 12, 543-559 (2013).
-
(2013)
Nat. Rev. Drug Discov.
, vol.12
, pp. 543-559
-
-
Barnes, P.J.1
-
189
-
-
34247607712
-
The safety and efficacy of infliximab in moderate-to-severe chronic obstructive pulmonary disease
-
Rennard, S. I. et al. The safety and efficacy of infliximab in moderate-to-severe chronic obstructive pulmonary disease. Am. J. Respir. Crit. Care Med. 175, 926-934 (2007).
-
(2007)
Am. J. Respir. Crit. Care Med.
, vol.175
, pp. 926-934
-
-
Rennard, S.I.1
-
190
-
-
84860172730
-
An oral inhibitor of p38 MAP kinase reduces plasma fibrinogen in patients with chronic obstructive pulmonary disease
-
Lomas, D. A. et al. An oral inhibitor of p38 MAP kinase reduces plasma fibrinogen in patients with chronic obstructive pulmonary disease. J. Clin. Pharmacol. 52, 416-424 (2011).
-
(2011)
J. Clin. Pharmacol.
, vol.52
, pp. 416-424
-
-
Lomas, D.A.1
-
191
-
-
77955664554
-
Tolerability and efficacy of inhaled AZD4818, a CCR1 antagonist, in moderate to severe COPD patients
-
Kerstjens, H. A., Bjermer, L., Eriksson, L., Dahlstrom, K. & Vestbo, J. Tolerability and efficacy of inhaled AZD4818, a CCR1 antagonist, in moderate to severe COPD patients. Respir. Med. 104, 1297-1303 (2010).
-
(2010)
Respir. Med.
, vol.104
, pp. 1297-1303
-
-
Kerstjens, H.A.1
Bjermer, L.2
Eriksson, L.3
Dahlstrom, K.4
Vestbo, J.5
-
192
-
-
65849427529
-
Glucocorticoid resistance in inflammatory diseases
-
Barnes, P. J. & Adcock, I. M. Glucocorticoid resistance in inflammatory diseases. Lancet 342, 1905-1917 (2009).
-
(2009)
Lancet
, vol.342
, pp. 1905-1917
-
-
Barnes, P.J.1
Adcock, I.M.2
-
193
-
-
69249117423
-
New drugs for exacerbations of chronic obstructive pulmonary disease
-
Hansel, T. T. & Barnes, P. J. New drugs for exacerbations of chronic obstructive pulmonary disease. Lancet 374, 744-755 (2009).
-
(2009)
Lancet
, vol.374
, pp. 744-755
-
-
Hansel, T.T.1
Barnes, P.J.2
-
194
-
-
84907211818
-
Network medicine, multimorbidity and the lung in the elderly
-
Faner, R., Cruz, T., Lopez-Giraldo, A. & Agusti, A. Network medicine, multimorbidity and the lung in the elderly. Eur. Respir. J. 44, 775-788 (2014).
-
(2014)
Eur. Respir. J.
, vol.44
, pp. 775-788
-
-
Faner, R.1
Cruz, T.2
Lopez-Giraldo, A.3
Agusti, A.4
|