Oxidative stress-induced antibodies to carbonyl-modified protein correlate with severity of chronic obstructive pulmonary disease

American Journal of Respiratory and Critical Care Medicine

Volumn 184, Issue 7, 2011, Pages 796-802

  Kirkham, Paul A ^a,b   Caramori, Gaetano ^c   Casolari, Paolo ^c   Papi, Alberto A ^c   Edwards, Matt ^b   Shamji, Betty ^b   Triantaphyllopoulos, Kostas ^a   Hussain, Farhana ^a   Pinart, Mariona ^a   Khan, Younis ^a   Heinemann, Lucy ^a   Stevens, Laurie ^a   Yeadon, Mike ^a   Barnes, Peter J ^a,d   Chung, Kian F ^a,d   Adcock, Ian M ^a,d  

^a NATIONAL HEART AND LUNG INSTITUTE   (United Kingdom)

^b NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH   (United States)

^c UNIVERSITY OF FERRARA   (Italy)

^d ROYAL BROMPTON HOSPITAL   (United Kingdom)

Author keywords

Autoimmunity; Carbonyl; COPD; Oxidative stress

Indexed keywords

AUTOANTIBODY; CARBONYL DERIVATIVE; IMMUNOGLOBULIN G1; OZONE;

ADULT; AGED; AMBIENT AIR; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY PRODUCTION; ANTIBODY TITER; ARTICLE; ASTHMA; BLOOD; CELL ACTIVATION; CHRONIC OBSTRUCTIVE LUNG DISEASE; CLINICAL ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; DISEASE SEVERITY; ENDOTHELIUM CELL; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; FLUORESCENCE ACTIVATED CELL SORTER; HUMAN; IMMUNE RESPONSE; IMMUNOHISTOCHEMISTRY; LUNG FUNCTION; LUNG PARENCHYMA; MALE; MOUSE; NONHUMAN; OXIDATIVE STRESS; PERIPHERAL LUNG LESION; PRIORITY JOURNAL; PROTEIN MODIFICATION; SMOKING; SPLEEN CELL; VESSEL;

AGED; ANIMALS; ASTHMA; AUTOANTIBODIES; CASE-CONTROL STUDIES; FEMALE; HUMANS; MALE; MATCHED-PAIR ANALYSIS; MICE; MICE, INBRED BALB C; MIDDLE AGED; OXIDATIVE STRESS; OZONE; PROTEIN CARBONYLATION; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; RESPIRATORY MUCOSA; SEVERITY OF ILLNESS INDEX; SMOKING;

EID: 80053428842     PISSN: 1073449X     EISSN: 15354970     Source Type: Journal    
DOI: 10.1164/rccm.201010-1605OC     Document Type: Article

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