-
1
-
-
81055144784
-
Autophagy: Renovation of cells and tissues
-
Mizushima N, Komatsu M. Autophagy: renovation of cells and tissues. Cell. 2011;147(4):728-741.
-
(2011)
Cell
, vol.147
, Issue.4
, pp. 728-741
-
-
Mizushima, N.1
Komatsu, M.2
-
2
-
-
53749087325
-
Egr-1 regulates autophagy in cigarette smoke-induced chronic obstructive pulmonary disease
-
Chen ZH, Kim HP, Sciurba FC, et al. Egr-1 regulates autophagy in cigarette smoke-induced chronic obstructive pulmonary disease. PLoS ONE. 2008;3(10):e3316.
-
(2008)
PLoS ONE
, vol.3
, Issue.10
-
-
Chen, Z.H.1
Kim, H.P.2
Sciurba, F.C.3
-
3
-
-
78650434097
-
Autophagy protein microtubule-associated protein 1 light chain-3B (LC3B) activates extrinsic apoptosis during cigarette smoke-induced emphysema
-
Chen ZH, Lam HC, Jin Y, et al. Autophagy protein microtubule-associated protein 1 light chain-3B (LC3B) activates extrinsic apoptosis during cigarette smoke-induced emphysema. Proc Natl Acad Sci U S A. 2010;107(44):18880-18885.
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, Issue.44
, pp. 18880-18885
-
-
Chen, Z.H.1
Lam, H.C.2
Jin, Y.3
-
4
-
-
78149476302
-
Identification of an autophagy defect in smokers' alveolar macrophages
-
Monick MM, Powers LS, Walters K, et al. Identification of an autophagy defect in smokers' alveolar macrophages. J Immunol. 2010;185(9):5425-5435.
-
(2010)
J Immunol
, vol.185
, Issue.9
, pp. 5425-5435
-
-
Monick, M.M.1
Powers, L.S.2
Walters, K.3
-
5
-
-
39449111277
-
Sequestration of mutated alpha1-antitrypsin into inclusion bodies is a cell-protective mechanism to maintain endoplasmic reticulum function
-
DOI 10.1091/mbc.E07-06-0587
-
Granell S, Baldini G, Mohammad S, et al. Sequestration of mutated alpha1-antitrypsin into inclusion bodies is a cell-protective mechanism to maintain endoplasmic reticulum function. Mol Biol Cell. 2008;19(2):572-586. (Pubitemid 351272146)
-
(2008)
Molecular Biology of the Cell
, vol.19
, Issue.2
, pp. 572-586
-
-
Granell, S.1
Baldini, G.2
Mohammad, S.3
Nicolin, V.4
Narducci, P.5
Storrie, B.6
Baldini, G.7
-
6
-
-
77954597127
-
An autophagy-enhancing drug promotes degradation of mutant alpha1-antitrypsin Z and reduces hepatic fibrosis
-
Hidvegi T, Ewing M, Hale P, et al. An autophagy-enhancing drug promotes degradation of mutant alpha1-antitrypsin Z and reduces hepatic fibrosis. Science. 2010;329(5988):229-232.
-
(2010)
Science
, vol.329
, Issue.5988
, pp. 229-232
-
-
Hidvegi, T.1
Ewing, M.2
Hale, P.3
-
7
-
-
33645216184
-
1-antitrypsin Z are propagated in the absence of autophagic activity
-
DOI 10.1074/jbc.M509409200
-
Kamimoto T, Shoji S, Hidvegi T, et al. Intracellular inclusions containing mutant alpha1-antitrypsin Z are propagated in the absence of autophagic activity. J Biol Chem. 2006;281(7):4467-4476. (Pubitemid 43847878)
-
(2006)
Journal of Biological Chemistry
, vol.281
, Issue.7
, pp. 4467-4476
-
-
Kamimoto, T.1
Shoji, S.2
Hidvegi, T.3
Mizushima, N.4
Umebayashi, K.5
Perlmutter, D.H.6
Yoshimori, T.7
-
8
-
-
79952217657
-
Autophagic protein LC3B confers resistance against hypoxia-induced pulmonary hypertension
-
Lee SJ, Smith A, Guo L, et al. Autophagic protein LC3B confers resistance against hypoxia-induced pulmonary hypertension. Am J Respir Crit Care Med. 2010;183(5):649-658.
-
(2010)
Am J Respir Crit Care Med
, vol.183
, Issue.5
, pp. 649-658
-
-
Lee, S.J.1
Smith, A.2
Guo, L.3
-
9
-
-
84859447737
-
Cross-talk between NADPH oxidase and autophagy in pulmonary artery endothelial cells with intrauterine persistent pulmonary hypertension
-
Teng RJ, Du J, Welak S, et al. Cross-talk between NADPH oxidase and autophagy in pulmonary artery endothelial cells with intrauterine persistent pulmonary hypertension. Am J Physiol Lung Cell Mol Physiol. 2012;302(7):L651- L663.
-
(2012)
Am J Physiol Lung Cell Mol Physiol
, vol.302
, Issue.7
-
-
Teng, R.J.1
Du, J.2
Welak, S.3
-
10
-
-
80053638297
-
Carbon monoxide activates autophagy via mitochondrial reactive oxygen species formation
-
Lee SJ, Ryter SW, Xu JF, et al. Carbon monoxide activates autophagy via mitochondrial reactive oxygen species formation. Am J Respir Cell Mol Biol. 2011;45(4):867-873.
-
(2011)
Am J Respir Cell Mol Biol
, vol.45
, Issue.4
, pp. 867-873
-
-
Lee, S.J.1
Ryter, S.W.2
Xu, J.F.3
-
11
-
-
84859383698
-
Hyperoxia induced LC3B interacts with the Fas apoptotic pathway in epithelial cell death
-
Tanaka A, Jin Y, Lee SJ, et al. Hyperoxia induced LC3B interacts with the Fas apoptotic pathway in epithelial cell death. Am J Respir Cell Mol Biol. 2011;46(4):507-514.
-
(2011)
Am J Respir Cell Mol Biol
, vol.46
, Issue.4
, pp. 507-514
-
-
Tanaka, A.1
Jin, Y.2
Lee, S.J.3
-
12
-
-
77953139736
-
Fighting disease by selective autophagy of aggregate-prone proteins
-
Knævelsrud H, Simonsen A. Fighting disease by selective autophagy of aggregate-prone proteins. FEBS Lett. 2010;584(12):2635-2645.
-
(2010)
FEBS Lett
, vol.584
, Issue.12
, pp. 2635-2645
-
-
Knævelsrud, H.1
Simonsen, A.2
-
13
-
-
77956396747
-
Defective CFTR induces aggresome formation and lung inflammation in cystic fibrosis through ROS-mediated autophagy inhibition
-
Luciani A, Villella VR, Esposito S, et al. Defective CFTR induces aggresome formation and lung inflammation in cystic fibrosis through ROS-mediated autophagy inhibition. Nat Cell Biol. 2010;12(9):863-875.
-
(2010)
Nat Cell Biol
, vol.12
, Issue.9
, pp. 863-875
-
-
Luciani, A.1
Villella, V.R.2
Esposito, S.3
-
14
-
-
70349672696
-
Autophagy gene variant IRGM -261T contributes to protection from tuberculosis caused by Mycobacterium tuberculosis but not by M. africanum strains
-
Intemann CD, Thye T, Niemann S, et al. Autophagy gene variant IRGM -261T contributes to protection from tuberculosis caused by Mycobacterium tuberculosis but not by M. africanum strains. PLoS Pathog. 2009;5(9):e1000577.
-
(2009)
PLoS Pathog
, vol.5
, Issue.9
-
-
Intemann, C.D.1
Thye, T.2
Niemann, S.3
-
15
-
-
84861180818
-
Host cell autophagy activated by antibiotics is required for their effective antimycobacterial drug action
-
Kim JJ, Lee HM, Shin DM, et al. Host cell autophagy activated by antibiotics is required for their effective antimycobacterial drug action. Cell Host Microbe. 2012;11(5):457-468.
-
(2012)
Cell Host Microbe
, vol.11
, Issue.5
, pp. 457-468
-
-
Kim, J.J.1
Lee, H.M.2
Shin, D.M.3
-
16
-
-
77649112187
-
Genome-wide analysis of the host intracellular network that regulates survival of Mycobacterium tuberculosis
-
Kumar D, Nath L, Kamal MA, et al. Genome-wide analysis of the host intracellular network that regulates survival of Mycobacterium tuberculosis. Cell. 2010;140(5):731-743.
-
(2010)
Cell
, vol.140
, Issue.5
, pp. 731-743
-
-
Kumar, D.1
Nath, L.2
Kamal, M.A.3
-
17
-
-
84863671626
-
Nitazoxanide stimulates autophagy and inhibits mTORC1 signaling and intracellular proliferation of Mycobacterium tuberculosis
-
Lam KK, Zheng X, Forestieri R, et al. Nitazoxanide stimulates autophagy and inhibits mTORC1 signaling and intracellular proliferation of Mycobacterium tuberculosis. PLoS Pathog. 2012;8(5):e1002691.
-
(2012)
PLoS Pathog
, vol.8
, Issue.5
-
-
Lam, K.K.1
Zheng, X.2
Forestieri, R.3
-
18
-
-
80052378958
-
Azithromycin blocks autophagy and may predispose cystic fibrosis patients to mycobacterial infection
-
Renna M, Schaffner C, Brown K, et al. Azithromycin blocks autophagy and may predispose cystic fibrosis patients to mycobacterial infection. J Clin Invest. 2011;121(9):3554-3563.
-
(2011)
J Clin Invest
, vol.121
, Issue.9
, pp. 3554-3563
-
-
Renna, M.1
Schaffner, C.2
Brown, K.3
-
19
-
-
33748506089
-
Human IRGM induces autophagy to eliminate intracellular mycobacteria
-
DOI 10.1126/science.1129577
-
Singh SB, Davis AS, Taylor GA, Deretic V. Human IRGM induces autophagy to eliminate intracellular mycobacteria. Science. 2006;313(5792):1438-1441. (Pubitemid 44360272)
-
(2006)
Science
, vol.313
, Issue.5792
, pp. 1438-1441
-
-
Singh, S.B.1
Davis, A.S.2
Taylor, G.A.3
Deretic, V.4
-
20
-
-
79951642032
-
Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome
-
Nakahira K, Haspel JA, Rathinam VAK, et al. Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome. Nat Immunol. 2010;12(3):222-230.
-
(2010)
Nat Immunol
, vol.12
, Issue.3
, pp. 222-230
-
-
Nakahira, K.1
Haspel, J.A.2
Rathinam, V.A.K.3
-
21
-
-
78651393239
-
A role for mitochondria in NLRP3 inflammasome activation
-
Zhou R, Yazdi AS, Menu P, Tschopp J. A role for mitochondria in NLRP3 inflammasome activation. Nature. 2010;469(7329):221-225.
-
(2010)
Nature
, vol.469
, Issue.7329
, pp. 221-225
-
-
Zhou, R.1
Yazdi, A.S.2
Menu, P.3
Tschopp, J.4
-
22
-
-
0027424777
-
Isolation and characterization of autophagy-defective mutants of Saccharomyces cerevisiae
-
DOI 10.1016/0014-5793(93)80398-E
-
Tsukada M, Ohsumi Y. Isolation and characterization of autophagy-defective mutants of Saccharomyces cerevisiae. FEBS Lett. 1993;333(1-2):169-174. (Pubitemid 23306962)
-
(1993)
FEBS Letters
, vol.333
, Issue.1-2
, pp. 169-174
-
-
Tsukada, M.1
Ohsumi, Y.2
-
23
-
-
10744225487
-
A unified nomenclature for yeast autophagy-related genes
-
DOI 10.1016/S1534-5807(03)00296-X, PII S153458070300296X
-
Klionsky DJ, Cregg JM, Dunn WA Jr, et al. A unified nomenclature for yeast autophagy-related genes. Dev Cell. 2003;5(4):539-545. (Pubitemid 37243044)
-
(2003)
Developmental Cell
, vol.5
, Issue.4
, pp. 539-545
-
-
Klionsky, D.J.1
Cregg, J.M.2
Dunn Jr., W.A.3
Emr, S.D.4
Sakai, Y.5
Sandoval, I.V.6
Sibirny, A.7
Subramani, S.8
Thumm, M.9
Veenhuis, M.10
Ohsumi, Y.11
-
24
-
-
0000906170
-
Induction of autophagy and inhibition of tumorigenesis by beclin 1
-
Liang XH, Jackson S, Seaman M, et al. Induction of autophagy and inhibition of tumorigenesis by Beclin 1. Nature. 1999;402(6762):672-676. (Pubitemid 129516338)
-
(1999)
Nature
, vol.402
, Issue.6762
, pp. 672-676
-
-
Liang, X.H.1
Jackson, S.2
Seaman, M.3
Brown, K.4
Kempkes, B.5
Hibshoosh, H.6
Levine, B.7
-
25
-
-
78751672975
-
Autophagy in immunity and inflammation
-
Levine B, Mizushima N, Virgin HW. Autophagy in immunity and inflammation. Nature. 2011;469(7330):323-335.
-
(2011)
Nature
, vol.469
, Issue.7330
, pp. 323-335
-
-
Levine, B.1
Mizushima, N.2
Virgin, H.W.3
-
26
-
-
3242888703
-
LC3, GABARAP and GATE16 localize to autophagosomal membrane depending on form-II formation
-
DOI 10.1242/jcs.01131
-
Kabeya Y, Mizushima N, Yamamoto A, Oshitani-Okamoto S, Ohsumi Y, Yoshimori T. LC3, GABARAP and GATE16 localize to autophagosomal membrane depending on form-II formation. J Cell Sci. 2004;117(pt 13):2805-2812. (Pubitemid 38997262)
-
(2004)
Journal of Cell Science
, vol.117
, Issue.13
, pp. 2805-2812
-
-
Kabeya, Y.1
Mizushima, N.2
Yamamoto, A.3
Oshitani-Okamoto, S.4
Ohsumi, Y.5
Yoshimori, T.6
-
27
-
-
75749122303
-
Methods in mammalian autophagy research
-
Mizushima N, Yoshimori T, Levine B. Methods in mammalian autophagy research. Cell. 2010;140(3):313-326.
-
(2010)
Cell
, vol.140
, Issue.3
, pp. 313-326
-
-
Mizushima, N.1
Yoshimori, T.2
Levine, B.3
-
28
-
-
79957886201
-
Characterization of macroautophagic flux in vivo using a leupeptin-based assay
-
Haspel J, Shaik RS, Ifedigbo E, et al. Characterization of macroautophagic flux in vivo using a leupeptin-based assay. Autophagy. 2011;7(6):629-642.
-
(2011)
Autophagy
, vol.7
, Issue.6
, pp. 629-642
-
-
Haspel, J.1
Shaik, R.S.2
Ifedigbo, E.3
-
29
-
-
10344262564
-
Role of Bcl-2 family proteins in a non-apoptopic programmed cell death dependent on autophagy genes
-
DOI 10.1038/ncb1192
-
Shimizu S, Kanaseki T, Mizushima N, et al. Role of Bcl-2 family proteins in a non-apoptotic programmed cell death dependent on autophagy genes. Nat Cell Biol. 2004;6(12):1221-1228. (Pubitemid 39625121)
-
(2004)
Nature Cell Biology
, vol.6
, Issue.12
, pp. 1221-1228
-
-
Shimizu, S.1
Kanaseki, T.2
Mizushima, N.3
Mizuta, T.4
Arakawa-Kobayashi, S.5
Thompson, C.B.6
Tsujimoto, Y.7
-
30
-
-
36849088609
-
Growth Arrest and Autophagy Are Required for Salivary Gland Cell Degradation in Drosophila
-
DOI 10.1016/j.cell.2007.10.048, PII S009286740701402X
-
Berry DL, Baehrecke EH. Growth arrest and autophagy are required for salivary gland cell degradation in Drosophila. Cell. 2007;131(6):1137-1148. (Pubitemid 350235023)
-
(2007)
Cell
, vol.131
, Issue.6
, pp. 1137-1148
-
-
Berry, D.L.1
Baehrecke, E.H.2
-
31
-
-
84255210700
-
Molecular definitions of cell death subroutines: Recommendations of the Nomenclature Committee on Cell Death 2012
-
Galluzzi L, Vitale I, Abrams JM, et al. Molecular definitions of cell death subroutines: recommendations of the Nomenclature Committee on Cell Death 2012. Cell Death Differ. 2012;19(1):107-120.
-
(2012)
Cell Death Differ
, vol.19
, Issue.1
, pp. 107-120
-
-
Galluzzi, L.1
Vitale, I.2
Abrams, J.M.3
-
32
-
-
56749170677
-
Autophagic cell death: The story of a misnomer
-
Kroemer G, Levine B. Autophagic cell death: the story of a misnomer. Nat Rev Mol Cell Biol. 2008;9(12):1004-1010.
-
(2008)
Nat Rev Mol Cell Biol
, vol.9
, Issue.12
, pp. 1004-1010
-
-
Kroemer, G.1
Levine, B.2
-
33
-
-
48249092267
-
Bcl-2 family members: Dual regulators of apoptosis and autophagy
-
Levine B, Sinha S, Kroemer G. Bcl-2 family members: dual regulators of apoptosis and autophagy. Autophagy. 2008;4(5):600-606.
-
(2008)
Autophagy
, vol.4
, Issue.5
, pp. 600-606
-
-
Levine, B.1
Sinha, S.2
Kroemer, G.3
-
34
-
-
0037452564
-
A SAGE approach to discovery of genes involved in autophagic cell death
-
DOI 10.1016/S0960-9822(03)00082-4, PII S0960982203000824
-
Gorski SM, Chittaranjan S, Pleasance ED, et al. A SAGE approach to discovery of genes involved in autophagic cell death. Curr Biol. 2003;13(4):358-363. (Pubitemid 36230029)
-
(2003)
Current Biology
, vol.13
, Issue.4
, pp. 358-363
-
-
Gorski, S.M.1
Chittaranjan, S.2
Pleasance, E.D.3
Freeman, J.D.4
Anderson, C.L.5
Varhol, R.J.6
Coughlin, S.M.7
Zuyderduyn, S.D.8
Jones, S.J.M.9
Marra, M.A.10
-
35
-
-
65549085701
-
Cullin3-based polyubiquitination and p62-dependent aggregation of caspase-8 mediate extrinsic apoptosis signaling
-
Jin Z, Li Y, Pitti R, et al. Cullin3-based polyubiquitination and p62-dependent aggregation of caspase-8 mediate extrinsic apoptosis signaling. Cell. 2009;137(4):721-735.
-
(2009)
Cell
, vol.137
, Issue.4
, pp. 721-735
-
-
Jin, Z.1
Li, Y.2
Pitti, R.3
-
36
-
-
0030883558
-
Inhibition of autophagy abrogates tumour necrosis factor alpha induced apoptosis in human T-lymphoblastic leukaemic cells
-
Jia L, Dourmashkin RR, Allen PD, Gray AB, Newland AC, Kelsey SM. Inhibition of autophagy abrogates tumour necrosis factor alpha induced apoptosis in human T-lymphoblastic leukaemic cells. Br J Haematol. 1997;98(3):673-685. (Pubitemid 27386551)
-
(1997)
British Journal of Haematology
, vol.98
, Issue.3
, pp. 673-685
-
-
Jia, L.1
Dourmashkin, R.R.2
Allen, P.D.3
Gray, A.B.4
Newland, A.C.5
Kelsey, S.M.6
-
37
-
-
62649146372
-
TAK1 activates AMPK-dependent cytoprotective autophagy in TRAIL-treated epithelial cells
-
Herrero-Martín G, Høyer-Hansen M, García- García C, et al. TAK1 activates AMPK-dependent cytoprotective autophagy in TRAIL-treated epithelial cells. EMBO J. 2009;28(6):677-685.
-
(2009)
EMBO J
, vol.28
, Issue.6
, pp. 677-685
-
-
Herrero-Martín, G.1
Høyer-Hansen, M.2
García- García, C.3
-
38
-
-
20144381544
-
Essential roles of Atg5 and FADD in autophagic cell death: Dissection of autophagic cell death into vacuole formation and cell death
-
Pyo JO, Jang MH, Kwon YK, et al. Essential roles of Atg5 and FADD in autophagic cell death: dissection of autophagic cell death into vacuole formation and cell death. J Biol Chem. 2005;280(21):20722-20729.
-
(2005)
J Biol Chem
, vol.280
, Issue.21
, pp. 20722-20729
-
-
Pyo, J.O.1
Jang, M.H.2
Kwon, Y.K.3
-
39
-
-
0037193474
-
DAP kinase and DRP-1 mediate membrane blebbing and the formation of autophagic vesicles during programmed cell death
-
DOI 10.1083/jcb.200109094
-
Inbal B, Bialik S, Sabanay I, Shani G, Kimchi A. DAP kinase and DRP-1 mediate membrane blebbing and the formation of autophagic vesicles during programmed cell death. J Cell Biol. 2002;157(3):455-468. (Pubitemid 34839809)
-
(2002)
Journal of Cell Biology
, vol.157
, Issue.3
, pp. 455-468
-
-
Inbal, B.1
Bialik, S.2
Sabanay, I.3
Shani, G.4
Kimchi, A.5
-
40
-
-
78751655392
-
Bcl-2 and Bcl-xL play important roles in the crosstalk between autophagy and apoptosis
-
Zhou F, Yang Y, Xing D. Bcl-2 and Bcl-xL play important roles in the crosstalk between autophagy and apoptosis. FEBS J. 2011;278(3):403-413.
-
(2011)
FEBS J
, vol.278
, Issue.3
, pp. 403-413
-
-
Zhou, F.1
Yang, Y.2
Xing, D.3
-
41
-
-
25144457455
-
Bcl-2 antiapoptotic proteins inhibit Beclin 1-dependent autophagy
-
DOI 10.1016/j.cell.2005.07.002, PII S0092867405006926
-
Pattingre S, Tassa A, Qu X, et al. Bcl-2 antiapoptotic proteins inhibit Beclin 1-dependent autophagy. Cell. 2005;122(6):927-939. (Pubitemid 41345209)
-
(2005)
Cell
, vol.122
, Issue.6
, pp. 927-939
-
-
Pattingre, S.1
Tassa, A.2
Qu, X.3
Garuti, R.4
Xiao, H.L.5
Mizushima, N.6
Packer, M.7
Schneider, M.D.8
Levine, B.9
-
42
-
-
84865128914
-
Cleavage of Atg3 protein by caspase-8 regulates autophagy during receptor-activated cell death
-
Oral O, Oz-Arslan D, Itah Z, et al. Cleavage of Atg3 protein by caspase-8 regulates autophagy during receptor-activated cell death. Apoptosis. 2012;17(8):810-820.
-
(2012)
Apoptosis
, vol.17
, Issue.8
, pp. 810-820
-
-
Oral, O.1
Oz-Arslan, D.2
Itah, Z.3
-
43
-
-
84555187749
-
Mammalian target of rapamycin: A signaling kinase for every aspect of cellular life
-
Weichhart T. Mammalian target of rapamycin: a signaling kinase for every aspect of cellular life. Methods Mol Biol. 2012;821:1-14.
-
(2012)
Methods Mol Biol
, vol.821
, pp. 1-14
-
-
Weichhart, T.1
-
44
-
-
65549142204
-
A role for ubiquitin in selective autophagy
-
Kirkin V, McEwan DG, Novak I, Dikic I. A role for ubiquitin in selective autophagy. Mol Cell. 2009;34(3):259-269.
-
(2009)
Mol Cell
, vol.34
, Issue.3
, pp. 259-269
-
-
Kirkin, V.1
McEwan, D.G.2
Novak, I.3
Dikic, I.4
-
45
-
-
77955493107
-
Mechanisms of mono- and polyubiquitination: Ubiquitination specificity depends on compatibility between the E2 catalytic core and amino acid residues proximal to the lysine
-
Sadowski M, Sarcevic B. Mechanisms of mono- and polyubiquitination: ubiquitination specificity depends on compatibility between the E2 catalytic core and amino acid residues proximal to the lysine. Cell Div. 2010;5:19.
-
(2010)
Cell Div
, vol.5
, pp. 19
-
-
Sadowski, M.1
Sarcevic, B.2
-
46
-
-
79953153831
-
Selective degradation of p62 by autophagy
-
Ichimura Y, Komatsu M. Selective degradation of p62 by autophagy. Semin Immunopathol. 2010;32(4):431-436.
-
(2010)
Semin Immunopathol
, vol.32
, Issue.4
, pp. 431-436
-
-
Ichimura, Y.1
Komatsu, M.2
-
47
-
-
58549084167
-
Ubiquitin signals autophagic degradation of cytosolic proteins and peroxisomes
-
Kim PK, Hailey DW, Mullen RT, Lippincott-Schwartz J. Ubiquitin signals autophagic degradation of cytosolic proteins and peroxisomes. Proc Natl Acad Sci U S A. 2008;105(52):20567-20574.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, Issue.52
, pp. 20567-20574
-
-
Kim, P.K.1
Hailey, D.W.2
Mullen, R.T.3
Lippincott-Schwartz, J.4
-
49
-
-
12944308330
-
Eating oneself and uninvited guests: Autophagy-related pathways in cellular defense
-
DOI 10.1016/j.cell.2005.01.005, PII S0092867405000437
-
Levine B. Eating oneself and uninvited guests: autophagy-related pathways in cellular defense. Cell. 2005;120(2):159-162. (Pubitemid 40174758)
-
(2005)
Cell
, vol.120
, Issue.2
, pp. 159-162
-
-
Levine, B.1
-
50
-
-
79960804104
-
Phosphorylation of the autophagy receptor optineurin restricts Salmonella growth
-
Wild P, Farhan H, McEwan DG, et al. Phosphorylation of the autophagy receptor optineurin restricts Salmonella growth. Science. 2011;333(6039):228- 233.
-
(2011)
Science
, vol.333
, Issue.6039
, pp. 228-233
-
-
Wild, P.1
Farhan, H.2
McEwan, D.G.3
-
51
-
-
60849099049
-
A role for NBR1 in autophagosomal degradation of ubiquitinated substrates
-
Kirkin V, Lamark T, Sou YS, et al. A role for NBR1 in autophagosomal degradation of ubiquitinated substrates. Mol Cell. 2009;33(4):505-516.
-
(2009)
Mol Cell
, vol.33
, Issue.4
, pp. 505-516
-
-
Kirkin, V.1
Lamark, T.2
Sou, Y.S.3
-
52
-
-
70350450808
-
The TBK1 adaptor and autophagy receptor NDP52 restricts the proliferation of ubiquitin-coated bacteria
-
Thurston TL, Ryzhakov G, Bloor S, von Muhlinen N, Randow F. The TBK1 adaptor and autophagy receptor NDP52 restricts the proliferation of ubiquitin-coated bacteria. Nat Immunol. 2009;10(11):1215-1221.
-
(2009)
Nat Immunol
, vol.10
, Issue.11
, pp. 1215-1221
-
-
Thurston, T.L.1
Ryzhakov, G.2
Bloor, S.3
Von Muhlinen, N.4
Randow, F.5
-
53
-
-
79952134938
-
A synonymous variant in IRGM alters a binding site for miR-196 and causes deregulation of IRGM-dependent xenophagy in Crohn's disease
-
Brest P, Lapaquette P, Souidi M, et al. A synonymous variant in IRGM alters a binding site for miR-196 and causes deregulation of IRGM-dependent xenophagy in Crohn's disease. Nat Genet. 2011;43(3):242-245.
-
(2011)
Nat Genet
, vol.43
, Issue.3
, pp. 242-245
-
-
Brest, P.1
Lapaquette, P.2
Souidi, M.3
-
54
-
-
79961055797
-
Intracellular recognition of pathogens and autophagy as an innate immune host defense
-
Yano T, Kurata S. Intracellular recognition of pathogens and autophagy as an innate immune host defense. J Biochem. 2011;150(2):143-149.
-
(2011)
J Biochem
, vol.150
, Issue.2
, pp. 143-149
-
-
Yano, T.1
Kurata, S.2
-
55
-
-
80052255017
-
Worldwide clinical interventional studies on leading causes of death: A descriptive analysis
-
Dal-Ré R. Worldwide clinical interventional studies on leading causes of death: a descriptive analysis. Ann Epidemiol. 2011;21(10):727-731.
-
(2011)
Ann Epidemiol
, vol.21
, Issue.10
, pp. 727-731
-
-
Dal-Ré, R.1
-
56
-
-
34548660457
-
Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: GOLD executive summary
-
DOI 10.1164/rccm.200703-456SO
-
Rabe KF, Hurd S, Anzueto A, et al Global Initiative for Chronic Obstructive Lung Disease. Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: GOLD executive summary. Am J Respir Crit Care Med. 2007;176(6):532-555. (Pubitemid 47403272)
-
(2007)
American Journal of Respiratory and Critical Care Medicine
, vol.176
, Issue.6
, pp. 532-555
-
-
Rabe, K.F.1
Hurd, S.2
Anzueto, A.3
Barnes, P.J.4
Buist, S.A.5
Calverley, P.6
Fukuchi, Y.7
Jenkins, C.8
Rodriguez-Roisin, R.9
Van Weel, C.10
Zielinski, J.11
-
57
-
-
4344675455
-
Pathophysiology of airflow limitation in chronic obstructive pulmonary disease
-
DOI 10.1016/S0140-6736(04)16900-6, PII S0140673604169006
-
Hogg JC. Pathophysiology of airflow limitation in chronic obstructive pulmonary disease. Lancet. 2004;364(9435):709-721. (Pubitemid 39140629)
-
(2004)
Lancet
, vol.364
, Issue.9435
, pp. 709-721
-
-
Hogg, J.C.1
-
58
-
-
77954470662
-
Rtp801, a suppressor of mTOR signaling, is an essential mediator of cigarette smoke-induced pulmonary injury and emphysema
-
Yoshida T, Mett I, Bhunia AK, et al. Rtp801, a suppressor of mTOR signaling, is an essential mediator of cigarette smoke-induced pulmonary injury and emphysema. Nat Med. 2010;16(7):767-773.
-
(2010)
Nat Med
, vol.16
, Issue.7
, pp. 767-773
-
-
Yoshida, T.1
Mett, I.2
Bhunia, A.K.3
-
59
-
-
80054997454
-
Pulmonary function, oxidative stress and inflammatory markers in severe COPD exacerbation
-
Stanojkovic I, Kotur-Stevuljevic J, Milenkovic B, et al. Pulmonary function, oxidative stress and inflammatory markers in severe COPD exacerbation. Respir Med. 2011;105(suppl 1):S31-S37.
-
(2011)
Respir Med
, vol.105
, Issue.SUPPL. 1
-
-
Stanojkovic, I.1
Kotur-Stevuljevic, J.2
Milenkovic, B.3
-
60
-
-
0346727128
-
Therapeutic approaches to protein-misfolding diseases
-
DOI 10.1038/nature02265
-
Cohen FE, Kelly JW. Therapeutic approaches to protein-misfolding diseases. Nature. 2003;426(6968):905-909. (Pubitemid 38056884)
-
(2003)
Nature
, vol.426
, Issue.6968
, pp. 905-909
-
-
Cohen, F.E.1
Kelly, J.W.2
-
61
-
-
50249175120
-
Chemical and biological approaches synergize to ameliorate protein-folding diseases
-
Mu TW, Ong DS, Wang YJ, et al. Chemical and biological approaches synergize to ameliorate protein-folding diseases. Cell. 2008;134(5):769-781.
-
(2008)
Cell
, vol.134
, Issue.5
, pp. 769-781
-
-
Mu, T.W.1
Ong, D.S.2
Wang, Y.J.3
-
62
-
-
33748069813
-
Chemical chaperones reduce ER stress and restore glucose homeostasis in a mouse model of type 2 diabetes
-
DOI 10.1126/science.1128294
-
Ozcan U, Yilmaz E, Ozcan L, et al. Chemical chaperones reduce ER stress and restore glucose homeostasis in a mouse model of type 2 diabetes. Science. 2006;313(5790):1137-1140. (Pubitemid 44300242)
-
(2006)
Science
, vol.313
, Issue.5790
, pp. 1137-1140
-
-
Ozcan, U.1
Yilmaz, E.2
Ozcan, L.3
Furuhashi, M.4
Vaillancourt, E.5
Smith, R.O.6
Gorgun, C.Z.7
Hotamisligil, G.S.8
-
63
-
-
78049498575
-
Alpha1-antitrypsin deficiency and autophagy
-
Marciniak SJ, Lomas DA. Alpha1-antitrypsin deficiency and autophagy. N Engl J Med. 2010;363(19):1863-1864.
-
(2010)
N Engl J Med
, vol.363
, Issue.19
, pp. 1863-1864
-
-
Marciniak, S.J.1
Lomas, D.A.2
-
65
-
-
0022472015
-
Expression of the alpha-1-antitrypsin gene in mononuclear phagocytes of normal and alpha-1- antitrypsin-deficient individuals
-
Mornex JF, Chytil-Weir A, Martinet Y, Courtney M, LeCocq JP, Crystal RG. Expression of the alpha-1-antitrypsin gene in mononuclear phagocytes of normal and alpha-1-antitrypsin-deficient individuals. J Clin Invest. 1986;77(6):1952-1961. (Pubitemid 16062652)
-
(1986)
Journal of Clinical Investigation
, vol.77
, Issue.6
, pp. 1952-1961
-
-
Mornex, J.-F.1
Chytil-Weir, A.2
Martinet, Y.3
-
67
-
-
5344233478
-
Pulmonary arterial hypertension
-
Farber HW, Loscalzo J. Pulmonary arterial hypertension. N Engl J Med. 2004;351(16):1655-1665.
-
(2004)
N Engl J Med
, vol.351
, Issue.16
, pp. 1655-1665
-
-
Farber, H.W.1
Loscalzo, J.2
-
68
-
-
80051625243
-
Oxygen sensing, homeostasis, and disease
-
Semenza GL. Oxygen sensing, homeostasis, and disease. N Engl J Med. 2011;365(6):537-547.
-
(2011)
N Engl J Med
, vol.365
, Issue.6
, pp. 537-547
-
-
Semenza, G.L.1
-
69
-
-
26844540049
-
Acute lung injury - Affecting many lives
-
DOI 10.1056/NEJMe058205
-
Herridge MS, Angus DC. Acute lung injury - affecting many lives. N Engl J Med. 2005;353(16):1736-1738. (Pubitemid 41464715)
-
(2005)
New England Journal of Medicine
, vol.353
, Issue.16
, pp. 1736-1738
-
-
Herridge, M.S.1
Angus, D.C.2
-
70
-
-
84859152309
-
Autophagic proteins: New facets of the oxygen paradox
-
Jin Y, Tanaka A, Choi AM, Ryter SW. Autophagic proteins: New facets of the oxygen paradox. Autophagy. 2012;8(3):8.
-
(2012)
Autophagy
, vol.8
, Issue.3
, pp. 8
-
-
Jin, Y.1
Tanaka, A.2
Choi, A.M.3
Ryter, S.W.4
-
71
-
-
0024453308
-
Identification of the cystic fibrosis gene: Chromosome walking and jumping
-
Rommens JM, Iannuzzi MC, Kerem B, et al. Identification of the cystic fibrosis gene: chromosome walking and jumping. Science. 1989;245(4922):1059- 1065. (Pubitemid 19231813)
-
(1989)
Science
, vol.245
, Issue.4922
, pp. 1059-1065
-
-
Rommens, J.M.1
Iannuzzi, M.C.2
Kerem, B.-S.3
Drumm, M.L.4
Melmer, G.5
Dean, M.6
Rozmahel, R.7
Cole, J.L.8
Kennedy, D.9
Hidaka, N.10
Zsiga, M.11
Buchwald, M.12
Riordan, J.R.13
Tsui, L.-C.14
Collins, F.S.15
-
72
-
-
0024424270
-
Identification of the cystic fibrosis gene: Cloning and characterization of complementary DNA
-
Riordan JR, Rommens JM, Kerem B, et al. Identification of the cystic fibrosis gene: cloning and characterization of complementary DNA. Science. 1989;245(4922):1066-1073. (Pubitemid 19231814)
-
(1989)
Science
, vol.245
, Issue.4922
, pp. 1066-1073
-
-
Riordan, J.R.1
Rommens, J.M.2
Kerem, B.-S.3
Alon, N.4
Rozmahel, R.5
Grzelczak, Z.6
Zielinski, J.7
Lok, S.8
Plavsic, N.9
Chou, J.-L.10
Drumm, M.L.11
Iannuzzi, M.C.12
Collins, F.S.13
Tsui, L.-C.14
-
73
-
-
0024423668
-
Identification of the cystic fibrosis gene: Genetic analysis
-
Kerem B, Rommens JM, Buchanan JA, et al. Identification of the cystic fibrosis gene: genetic analysis. Science. 1989;245(4922):1073-1080. (Pubitemid 19231815)
-
(1989)
Science
, vol.245
, Issue.4922
, pp. 1073-1080
-
-
Kerem, B.-S.1
Rommens, J.M.2
Buchanan, J.A.3
Markiewicz, D.4
Cox, T.K.5
Chakravarti, A.6
Buchwald, M.7
Tsui, L.-C.8
-
74
-
-
0035947372
-
Impairment of the ubiquitin-proteasome system by protein aggregation
-
DOI 10.1126/science.292.5521.1552
-
Bence NF, Sampat RM, Kopito RR. Impairment of the ubiquitin-proteasome system by protein aggregation. Science. 2001;292(5521):1552-1555. (Pubitemid 32493425)
-
(2001)
Science
, vol.292
, Issue.5521
, pp. 1552-1555
-
-
Bence, N.F.1
Sampat, R.M.2
Kopito, R.R.3
-
75
-
-
80655134731
-
Autophagy stimulation by rapamycin suppresses lung inflammation and infection by Burkholderia cenocepacia in a model of cystic fibrosis
-
Abdulrahman BA, Khweek AA, Akhter A, et al. Autophagy stimulation by rapamycin suppresses lung inflammation and infection by Burkholderia cenocepacia in a model of cystic fibrosis. Autophagy. 2011;7(11):1359-1370.
-
(2011)
Autophagy
, vol.7
, Issue.11
, pp. 1359-1370
-
-
Abdulrahman, B.A.1
Khweek, A.A.2
Akhter, A.3
-
76
-
-
84863714328
-
Vitamin D inhibits human immunodeficiency virus type 1 and Mycobacterium tuberculosis infection in macrophages through the induction of autophagy
-
Campbell GR, Spector SA, Vitamin D. Vitamin D inhibits human immunodeficiency virus type 1 and Mycobacterium tuberculosis infection in macrophages through the induction of autophagy. PLoS Pathog. 2012;8(5):e1002689.
-
(2012)
PLoS Pathog
, vol.8
, Issue.5
-
-
Campbell, G.R.1
Spector, S.A.2
Vitamin, D.3
-
77
-
-
84855293818
-
IRGM is a common target of RNA viruses that subvert the autophagy network
-
Grégoire IP, Richetta C, Meyniel-Schicklin L, et al. IRGM is a common target of RNA viruses that subvert the autophagy network. PLoS Pathog. 2011;7(12):e1002422.
-
(2011)
PLoS Pathog
, vol.7
, Issue.12
-
-
Grégoire, I.P.1
Richetta, C.2
Meyniel-Schicklin, L.3
-
78
-
-
84856711991
-
Totally drug-resistant tuberculosis in India
-
Udwadia ZF, Amale RA, Ajbani KK, Rodrigues C. Totally drug-resistant tuberculosis in India. Clin Infect Dis. 2012;54(4):579-581.
-
(2012)
Clin Infect Dis
, vol.54
, Issue.4
, pp. 579-581
-
-
Udwadia, Z.F.1
Amale, R.A.2
Ajbani, K.K.3
Rodrigues, C.4
-
79
-
-
34547114031
-
Systemic treatment with the antidiabetic drug metformin selectively impairs p53-deficient tumor cell growth
-
DOI 10.1158/0008-5472.CAN-06-4447
-
Buzzai M, Jones RG, Amaravadi RK, et al. Systemic treatment with the antidiabetic drug metformin selectively impairs p53-deficient tumor cell growth. Cancer Res. 2007;67(14):6745-6752. (Pubitemid 47105521)
-
(2007)
Cancer Research
, vol.67
, Issue.14
, pp. 6745-6752
-
-
Buzzai, M.1
Jones, R.G.2
Amaravadi, R.K.3
Lum, J.J.4
DeBerardinis, R.J.5
Zhao, F.6
Viollet, B.7
Thompson, C.B.8
-
80
-
-
42949162029
-
Inflammasome mRNA expression in human monocytes during early septic shock
-
DOI 10.1164/rccm.200703-418OC
-
Fahy RJ, Exline MC, Gavrilin MA, et al. Inflammasome mRNA expression in human monocytes during early septic shock. Am J Respir Crit Care Med. 2008;177(9):983-988. (Pubitemid 351717592)
-
(2008)
American Journal of Respiratory and Critical Care Medicine
, vol.177
, Issue.9
, pp. 983-988
-
-
Fahy, R.J.1
Exline, M.C.2
Gavrilin, M.A.3
Bhatt, N.Y.4
Besecker, B.Y.5
Sarkar, A.6
Hollyfield, J.L.7
Duncan, M.D.8
Nagaraja, H.N.9
Knatz, N.L.10
Hall, M.11
Wewers, M.D.12
-
81
-
-
84861184345
-
Hepcidin protects against lipopolysaccharide-induced liver injury in a mouse model of obstructive jaundice
-
Huang YH, Yang YL, Tiao MM, Kuo HC, Huang LT, Chuang JH. Hepcidin protects against lipopolysaccharide-induced liver injury in a mouse model of obstructive jaundice. Peptides. 2012;35(2):212-217.
-
(2012)
Peptides
, vol.35
, Issue.2
, pp. 212-217
-
-
Huang, Y.H.1
Yang, Y.L.2
Tiao, M.M.3
Kuo, H.C.4
Huang, L.T.5
Chuang, J.H.6
-
82
-
-
84868297984
-
Therapeutic potential of heme oxygenase-1/carbon monoxide in lung disease
-
Constantin M, Choi AJ, Cloonan SM, Ryter SW. Therapeutic potential of heme oxygenase-1/carbon monoxide in lung disease. Int J Hypertens. 2012;2012:859235.
-
(2012)
Int J Hypertens
, vol.2012
, pp. 859235
-
-
Constantin, M.1
Choi, A.J.2
Cloonan, S.M.3
Ryter, S.W.4
-
83
-
-
79952907081
-
The helminth product ES-62 protects against septic shock via Toll-like receptor 4-dependent autophagosomal degradation of the adaptor MyD88
-
Puneet P, McGrath MA, Tay HK, et al. The helminth product ES-62 protects against septic shock via Toll-like receptor 4-dependent autophagosomal degradation of the adaptor MyD88. Nat Immunol. 2011;12(4):344-351.
-
(2011)
Nat Immunol
, vol.12
, Issue.4
, pp. 344-351
-
-
Puneet, P.1
McGrath, M.A.2
Tay, H.K.3
|