NBS1 Phosphorylation Status Dictates Repair Choice of Dysfunctional Telomeres

Molecular Cell

Volumn 65, Issue 5, 2017, Pages 801-817.e4

  Rai, Rekha ^a   Hu, Chunyi ^b   Broton, Cayla ^a   Chen, Yong ^b,c   Lei, Ming ^b,c   Chang, Sandy ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b INSTITUTE OF BIOCHEMISTRY AND CELL BIOLOGY   (China)

^c INSTITUTE OF GEOLOGY AND GEOPHYSICS   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN DEPENDENT KINASE 2; HISTONE H2AX; NIBRIN; TELOMERIC REPEAT BINDING FACTOR 2; TUMOR SUPPRESSOR P53 BINDING PROTEIN 1; AMINOPEPTIDASE; ATM PROTEIN; ATM PROTEIN, HUMAN; BIRC6 PROTEIN, HUMAN; CDK2 PROTEIN, HUMAN; CELL CYCLE PROTEIN; DCLRE1B PROTEIN, HUMAN; DIPEPTIDYL PEPTIDASE; DNA LIGASE; INHIBITOR OF APOPTOSIS PROTEIN; NBN PROTEIN, HUMAN; NIJMEGEN BREAKAGE SYNDROME 1 PROTEIN, MOUSE; NUCLEAR PROTEIN; POT1 PROTEIN, HUMAN; PROTEIN BINDING; SERINE PROTEINASE; TELOMERE BINDING PROTEIN; TERF2 PROTEIN, HUMAN; TRF2 PROTEIN, MOUSE; TRIPEPTIDYL-PEPTIDASE 1;

ARTICLE; COMPLEX FORMATION; CONTROLLED STUDY; CRYSTAL STRUCTURE; DNA DAMAGE; DNA DAMAGE CHECKPOINT; DNA END JOINING REPAIR; DNA REPAIR; GENOMIC INSTABILITY; HCT 116 CELL LINE; HUMAN; HUMAN CELL; HYDROGEN BOND; ISOTHERMAL TITRATION CALORIMETRY; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; TELOMERE; TELOMERE HOMEOSTASIS; U2OS CELL LINE; BINDING SITE; CELL CYCLE G1 PHASE; CELL CYCLE G2 PHASE; CELL CYCLE S PHASE; CHEMISTRY; DOUBLE STRANDED DNA BREAK; GENETICS; METABOLISM; MOLECULAR MODEL; PATHOLOGY; PHOSPHORYLATION; PROTEIN DOMAIN; STRUCTURE ACTIVITY RELATION;

AMINOPEPTIDASES; ATAXIA TELANGIECTASIA MUTATED PROTEINS; BINDING SITES; CELL CYCLE PROTEINS; CYCLIN-DEPENDENT KINASE 2; DIPEPTIDYL-PEPTIDASES AND TRIPEPTIDYL-PEPTIDASES; DNA BREAKS, DOUBLE-STRANDED; DNA END-JOINING REPAIR; DNA REPAIR ENZYMES; G1 PHASE; G2 PHASE; HCT116 CELLS; HUMANS; INHIBITOR OF APOPTOSIS PROTEINS; MODELS, MOLECULAR; NUCLEAR PROTEINS; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN INTERACTION DOMAINS AND MOTIFS; S PHASE; SERINE PROTEASES; STRUCTURE-ACTIVITY RELATIONSHIP; TELOMERE; TELOMERE-BINDING PROTEINS; TELOMERIC REPEAT BINDING PROTEIN 2;

EID: 85012899182     PISSN: 10972765     EISSN: 10974164     Source Type: Journal    
DOI: 10.1016/j.molcel.2017.01.016     Document Type: Article

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