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Volumn 101, Issue 2, 2017, Pages 395-406

A protective role of IL-37 in cancer: A new hope for cancer patients

Author keywords

IL 18; IL 18BP; IL 18R ; SIGIRR; TIR 8

Indexed keywords

INTERLEUKIN 18; INTERLEUKIN 18 BINDING PROTEIN; INTERLEUKIN 37; INTERLEUKIN 37 RECEPTOR; INTERLEUKIN RECEPTOR; PROTEIN; TIR 8; UNCLASSIFIED DRUG; INTERLEUKIN DERIVATIVE; PROTECTIVE AGENT;

EID: 85011397664     PISSN: 07415400     EISSN: 19383673     Source Type: Journal    
DOI: 10.1189/jlb.5RU0816-341R     Document Type: Review
Times cited : (49)

References (87)
  • 2
    • 84883677974 scopus 로고    scopus 로고
    • New insights in the immunobiology of IL-1 family members
    • Van de Veerdonk, F. L., Netea, M. G. (2013) New insights in the immunobiology of IL-1 family members. Front. Immunol. 4, 167.
    • (2013) Front. Immunol , vol.4 , pp. 167
    • Van De Veerdonk, F.L.1    Netea, M.G.2
  • 3
    • 84922319788 scopus 로고    scopus 로고
    • IL-37: A new player in immune tolerance
    • Chen, H. M., Fujita, M. (2015) IL-37: a new player in immune tolerance. Cytokine 72, 113–114.
    • (2015) Cytokine , vol.72 , pp. 113-114
    • Chen, H.M.1    Fujita, M.2
  • 4
    • 84892860854 scopus 로고    scopus 로고
    • Interleukin-37. Semin
    • Dinarello, C. A., Bufler, P. (2013) Interleukin-37. Semin. Immunol. 25, 466–468.
    • (2013) Immunol , vol.25 , pp. 466-468
    • Dinarello, C.A.1    Bufler, P.2
  • 11
    • 84939775360 scopus 로고    scopus 로고
    • Interleukin 35 (IL-35) and IL-37: Intestinal and peripheral expression by T and B regulatory cells in patients with Inflammatory Bowel Disease
    • Fonseca-Camarillo, G., Furuzawa-Carballeda, J., Yamamoto-Furusho, J. K. (2015) Interleukin 35 (IL-35) and IL-37: Intestinal and peripheral expression by T and B regulatory cells in patients with Inflammatory Bowel Disease. Cytokine 75, 389–402.
    • (2015) Cytokine , vol.75 , pp. 389-402
    • Fonseca-Camarillo, G.1    Furuzawa-Carballeda, J.2    Yamamoto-Furusho, J.K.3
  • 12
    • 84942865248 scopus 로고    scopus 로고
    • Expression of IL-37 contributes to the immunosuppressive property of human CD4+CD25+ regulatory T cells
    • Shuai, X., Wei-min, L., Tong, Y. L., Dong, N., Sheng, Z. Y., Yao, Y. M. (2015) Expression of IL-37 contributes to the immunosuppressive property of human CD4+CD25+ regulatory T cells. Sci. Rep. 5, 14478.
    • (2015) Sci. Rep , vol.5
    • Shuai, X.1    Wei-Min, L.2    Tong, Y.L.3    Dong, N.4    Sheng, Z.Y.5    Yao, Y.M.6
  • 13
    • 3242790036 scopus 로고    scopus 로고
    • Interleukin-1 homologues IL-1F7b and IL-18 contain functional mRNA instability elements within the coding region responsive to lipopolysaccharide
    • Bufler, P., Gamboni-Robertson, F., Azam, T., Kim, S. H., Dinarello, C. A. (2004) Interleukin-1 homologues IL-1F7b and IL-18 contain functional mRNA instability elements within the coding region responsive to lipopolysaccharide. Biochem. J. 381, 503–510.
    • (2004) Biochem. J , vol.381 , pp. 503-510
    • Bufler, P.1    Gamboni-Robertson, F.2    Azam, T.3    Kim, S.H.4    Dinarello, C.A.5
  • 14
    • 84922394024 scopus 로고    scopus 로고
    • Long-range DNA interactions at the IL-1/IL-36/IL-37 gene cluster (2q13) are induced by activation of monocytes
    • Sharaf, N., Nicklin, M. J., di Giovine, F. S. (2014) Long-range DNA interactions at the IL-1/IL-36/IL-37 gene cluster (2q13) are induced by activation of monocytes. Cytokine 68, 16–22.
    • (2014) Cytokine , vol.68 , pp. 16-22
    • Sharaf, N.1    Nicklin, M.J.2    Di Giovine, F.S.3
  • 22
    • 45949111754 scopus 로고    scopus 로고
    • The IL-1 family member 7b translocates to the nucleus and down-regulates proinflammatory cytokines
    • Sharma, S., Kulk, N., Nold, M. F., Gräf, R., Kim, S. H., Reinhardt, D., Dinarello, C. A., Bufler, P. (2008) The IL-1 family member 7b translocates to the nucleus and down-regulates proinflammatory cytokines. J. Immunol. 180, 5477–5482.
    • (2008) J. Immunol , vol.180 , pp. 5477-5482
    • Sharma, S.1    Kulk, N.2    Nold, M.F.3    Gräf, R.4    Kim, S.H.5    Reinhardt, D.6    Dinarello, C.A.7    Bufler, P.8
  • 23
    • 0038682002 scopus 로고    scopus 로고
    • Mechanisms of TGF-b signaling from cell membrane to the nucleus
    • Shi, Y., Massagué, J. (2003) Mechanisms of TGF-b signaling from cell membrane to the nucleus. Cell 113, 685–700.
    • (2003) Cell , vol.113 , pp. 685-700
    • Shi, Y.1    Massagué, J.2
  • 24
    • 84892866814 scopus 로고    scopus 로고
    • The interleukin-1 receptor family
    • Boraschi, D., Tagliabue, A. (2013) The interleukin-1 receptor family. Semin. Immunol. 25, 394–407.
    • (2013) Semin. Immunol , vol.25 , pp. 394-407
    • Boraschi, D.1    Tagliabue, A.2
  • 27
    • 0033151633 scopus 로고    scopus 로고
    • Identification and characterization of SIGIRR, a molecule representing a novel subtype of the IL-1R superfamily
    • Thomassen, E., Renshaw, B. R., Sims, J. E. (1999) Identification and characterization of SIGIRR, a molecule representing a novel subtype of the IL-1R superfamily. Cytokine 11, 389–399.
    • (1999) Cytokine , vol.11 , pp. 389-399
    • Thomassen, E.1    Renshaw, B.R.2    Sims, J.E.3
  • 28
    • 84966702504 scopus 로고    scopus 로고
    • Regulatory role of IL-1R8 in immunity and disease. Front
    • Molgora, M., Barajon, I., Mantovani, A., Garlanda, C. (2016) Regulatory role of IL-1R8 in immunity and disease. Front. Immunol. 7, 149.
    • (2016) Immunol , vol.7 , pp. 149
    • Molgora, M.1    Barajon, I.2    Mantovani, A.3    Garlanda, C.4
  • 31
    • 84903545437 scopus 로고    scopus 로고
    • Lipopolysaccharide decreases single immunoglobulin interleukin-1 receptor-related molecule (SIGIRR) expression by suppressing specificity protein 1 (Sp1) via the Toll-like receptor 4 (TLR4)-p38 pathway in monocytes and neutrophils
    • Ueno-Shuto, K., Kato, K., Tasaki, Y., Sato, M., Sato, K., Uchida, Y., Sakai, H., Ono, T., Suico, M. A., Mitsutake, K., Tokutomi, N., Kai, H., Shuto, T. (2014) Lipopolysaccharide decreases single immunoglobulin interleukin-1 receptor-related molecule (SIGIRR) expression by suppressing specificity protein 1 (Sp1) via the Toll-like receptor 4 (TLR4)-p38 pathway in monocytes and neutrophils. J. Biol. Chem. 289, 18097–18109.
    • (2014) J. Biol. Chem , vol.289 , pp. 18097-18109
    • Ueno-Shuto, K.1    Kato, K.2    Tasaki, Y.3    Sato, M.4    Sato, K.5    Uchida, Y.6    Sakai, H.7    Ono, T.8    Suico, M.A.9    Mitsutake, K.10    Tokutomi, N.11    Kai, H.12    Shuto, T.13
  • 32
    • 78649403533 scopus 로고    scopus 로고
    • Differential regulation of Toll-like receptor signalling in spleen and Peyer’s patch dendritic cells
    • Davies, J. M., MacSharry, J., Shanahan, F. (2010) Differential regulation of Toll-like receptor signalling in spleen and Peyer’s patch dendritic cells. Immunology 131, 438–448.
    • (2010) Immunology , vol.131 , pp. 438-448
    • Davies, J.M.1    Macsharry, J.2    Shanahan, F.3
  • 34
    • 79952825184 scopus 로고    scopus 로고
    • The mechanism of excessive intestinal inflammation in necrotizing enterocolitis: An immature innate immune response
    • Nanthakumar, N., Meng, D., Goldstein, A. M., Zhu, W., Lu, L., Uauy, R., Llanos, A., Claud, E. C., Walker, W. A. (2011) The mechanism of excessive intestinal inflammation in necrotizing enterocolitis: an immature innate immune response. PLoS One 6, e17776.
    • (2011) Plos One , vol.6
    • Nanthakumar, N.1    Meng, D.2    Goldstein, A.M.3    Zhu, W.4    Lu, L.5    Uauy, R.6    Llanos, A.7    Claud, E.C.8    Walker, W.A.9
  • 36
    • 7444272876 scopus 로고    scopus 로고
    • Proteomics-based identification of proteins interacting with Smad3: SREBP-2 forms a complex with Smad3 and inhibits its transcriptional activity
    • Grimsby, S., Jaensson, H., Dubrovska, A., Lomnytska, M., Hellman, U., Souchelnytskyi, S. (2004) Proteomics-based identification of proteins interacting with Smad3: SREBP-2 forms a complex with Smad3 and inhibits its transcriptional activity. FEBS Lett. 577, 93–100.
    • (2004) FEBS Lett , vol.577 , pp. 93-100
    • Grimsby, S.1    Jaensson, H.2    Dubrovska, A.3    Lomnytska, M.4    Hellman, U.5    Souchelnytskyi, S.6
  • 37
    • 70350406465 scopus 로고    scopus 로고
    • The roles of Dok family adapters in immunoreceptor signaling
    • Mashima, R., Hishida, Y., Tezuka, T., Yamanashi, Y. (2009) The roles of Dok family adapters in immunoreceptor signaling. Immunol. Rev. 232, 273–285.
    • (2009) Immunol. Rev , vol.232 , pp. 273-285
    • Mashima, R.1    Hishida, Y.2    Tezuka, T.3    Yamanashi, Y.4
  • 38
    • 84859022123 scopus 로고    scopus 로고
    • The macrophage response towards LPS and its control through the p38 (MAPK)-STAT3 axis
    • Bode, J. G., Ehlting, C., Häussinger, D. (2012) The macrophage response towards LPS and its control through the p38 (MAPK)-STAT3 axis. Cell. Signal. 24, 1185–1194.
    • (2012) Cell. Signal , vol.24 , pp. 1185-1194
    • Bode, J.G.1    Ehlting, C.2    Häussinger, D.3
  • 39
    • 84946761239 scopus 로고    scopus 로고
    • IL-37 inhibits the production of pro-inflammatory cytokines in MSU crystal-induced inflammatory response
    • Zeng, M., Dang, W., Chen, B., Qing, Y., Xie, W., Zhao, M., Zhou, J. (2016) IL-37 inhibits the production of pro-inflammatory cytokines in MSU crystal-induced inflammatory response. Clin. Rheumatol. 35, 2251–2258.
    • (2016) Clin. Rheumatol , vol.35 , pp. 2251-2258
    • Zeng, M.1    Dang, W.2    Chen, B.3    Qing, Y.4    Xie, W.5    Zhao, M.6    Zhou, J.7
  • 40
    • 84911092624 scopus 로고    scopus 로고
    • Immunobiology of IL-37: Mechanism of action and clinical perspectives
    • Quirk, S., Agrawal, D. K. (2014) Immunobiology of IL-37: mechanism of action and clinical perspectives. Expert Rev. Clin. Immunol. 10, 1703–1709.
    • (2014) Expert Rev. Clin. Immunol , vol.10 , pp. 1703-1709
    • Quirk, S.1    Agrawal, D.K.2
  • 41
    • 84855585934 scopus 로고    scopus 로고
    • In vivo expression of interleukin-37 reduces local and systemic inflammation in concanavalin A-induced hepatitis
    • Bulau, A. M., Fink, M., Maucksch, C., Kappler, R., Mayr, D., Wagner, K., Bufler, P. (2011) In vivo expression of interleukin-37 reduces local and systemic inflammation in concanavalin A-induced hepatitis. Sci. World J. 11, 2480–2490.
    • (2011) Sci. World J , vol.11 , pp. 2480-2490
    • Bulau, A.M.1    Fink, M.2    Maucksch, C.3    Kappler, R.4    Mayr, D.5    Wagner, K.6    Bufler, P.7
  • 43
    • 84922240662 scopus 로고    scopus 로고
    • IL-37 inhibits IL-18-induced tubular epithelial cell expression of pro-inflammatory cytokines and renal ischemia-reperfusion injury
    • Yang, Y., Zhang, Z. X., Lian, D., Haig, A., Bhattacharjee, R. N., Jevnikar, A. M. (2015) IL-37 inhibits IL-18-induced tubular epithelial cell expression of pro-inflammatory cytokines and renal ischemia-reperfusion injury. Kidney Int. 87, 396–408.
    • (2015) Kidney Int , vol.87 , pp. 396-408
    • Yang, Y.1    Zhang, Z.X.2    Lian, D.3    Haig, A.4    Bhattacharjee, R.N.5    Jevnikar, A.M.6
  • 47
    • 68949181883 scopus 로고    scopus 로고
    • TIR8/SIGIRR: An IL-1R/TLR family member with regulatory functions in inflammation and T cell polarization
    • Garlanda, C., Anders, H. J., Mantovani, A. (2009) TIR8/SIGIRR: an IL-1R/TLR family member with regulatory functions in inflammation and T cell polarization. Trends Immunol. 30, 439–446.
    • (2009) Trends Immunol , vol.30 , pp. 439-446
    • Garlanda, C.1    Ers, H.J.2    Mantovani, A.3
  • 49
    • 84945450084 scopus 로고    scopus 로고
    • Insights into IL-37, the role in autoimmune diseases
    • Xu, W. D., Zhao, Y., Liu, Y. (2015) Insights into IL-37, the role in autoimmune diseases. Autoimmun. Rev. 14, 1170–1175.
    • (2015) Autoimmun. Rev , vol.14 , pp. 1170-1175
    • Xu, W.D.1    Zhao, Y.2    Liu, Y.3
  • 54
    • 84874217124 scopus 로고    scopus 로고
    • TIR8/SIGIRR is an interleukin-1 receptor/Toll like receptor family member with regulatory functions in inflammation and immunity
    • Riva, F., Bonavita, E., Barbati, E., Muzio, M., Mantovani, A., Garlanda, C. (2012) TIR8/SIGIRR is an interleukin-1 receptor/Toll like receptor family member with regulatory functions in inflammation and immunity. Front. Immunol. 3, 322.
    • (2012) Front. Immunol , vol.3 , pp. 322
    • Riva, F.1    Bonavita, E.2    Barbati, E.3    Muzio, M.4    Mantovani, A.5    Garlanda, C.6
  • 64
    • 77955485057 scopus 로고    scopus 로고
    • Loss of single immunoglobulin interlukin-1 receptor-related molecule leads to enhanced colonic polyposis in Apcmin mice
    • Xiao, H., Yin, W., Khan, M. A., Gulen, M. F., Zhou, H., Sham, H. P., Jacobson, K., Vallance, B. A., Li, X. (2010) Loss of single immunoglobulin interlukin-1 receptor-related molecule leads to enhanced colonic polyposis in Apcmin mice. Gastroenterology 139, 574–585.
    • (2010) Gastroenterology , vol.139 , pp. 574-585
    • Xiao, H.1    Yin, W.2    Khan, M.A.3    Gulen, M.F.4    Zhou, H.5    Sham, H.P.6    Jacobson, K.7    Vallance, B.A.8    Li, X.9
  • 67
    • 0037218354 scopus 로고    scopus 로고
    • Innate immunity mediated by the cytokine IL-1 homologue 4 (IL-1H4/IL-1F7) induces IL-12-dependent adaptive and profound antitumor immunity
    • Gao, W., Kumar, S., Lotze, M. T., Hanning, C., Robbins, P. D., Gambotto, A. (2003) Innate immunity mediated by the cytokine IL-1 homologue 4 (IL-1H4/IL-1F7) induces IL-12-dependent adaptive and profound antitumor immunity. J. Immunol. 170, 107–113.
    • (2003) J. Immunol , vol.170 , pp. 107-113
    • Gao, W.1    Kumar, S.2    Lotze, M.T.3    Hanning, C.4    Robbins, P.D.5    Gambotto, A.6
  • 70
    • 40649109728 scopus 로고    scopus 로고
    • The wolf in sheep’s clothing: The role of interleukin-6 in immunity, inflammation and cancer
    • Naugler, W. E., Karin, M. (2008) The wolf in sheep’s clothing: the role of interleukin-6 in immunity, inflammation and cancer. Trends Mol. Med. 14, 109–119.
    • (2008) Trends Mol. Med , vol.14 , pp. 109-119
    • Naugler, W.E.1    Karin, M.2
  • 71
    • 0036375050 scopus 로고    scopus 로고
    • Interleukin-1—a major pleiotropic cytokine in tumor-host interactions
    • Apte, R. N., Voronov, E. (2002) Interleukin-1—a major pleiotropic cytokine in tumor-host interactions. Semin. Cancer Biol. 12, 277–290.
    • (2002) Semin. Cancer Biol , vol.12 , pp. 277-290
    • Apte, R.N.1    Voronov, E.2
  • 72
    • 0034614637 scopus 로고    scopus 로고
    • The hallmarks of cancer
    • Hanahan, D., Weinberg, R. A. (2000) The hallmarks of cancer. Cell 100, 57–70.
    • (2000) Cell , vol.100 , pp. 57-70
    • Hanahan, D.1    Weinberg, R.A.2
  • 75
    • 84994112046 scopus 로고    scopus 로고
    • [IL-37 inhibits the proliferation, invasion and migration of SMMC-7721 cells in vitro]
    • Zhang, G., Tang, C., Tan, J., Liu, R., Zhou, M., Wu, Z. (2015) [IL-37 inhibits the proliferation, invasion and migration of SMMC-7721 cells in vitro]. Xibao Yu Fenzi Mianyixue Zazhi 31, 1301–1305.
    • (2015) Xibao Yu Fenzi Mianyixue Zazhi , vol.31 , pp. 1301-1305
    • Zhang, G.1    Tang, C.2    Tan, J.3    Liu, R.4    Zhou, M.5    Wu, Z.6
  • 78
    • 84958914373 scopus 로고    scopus 로고
    • Interleukin-37 suppresses tumor growth through inhibition of angiogenesis in non-small cell lung cancer
    • Ge, G., Wang, A., Yang, J., Chen, Y., Yang, J., Li, Y., Xue, Y. (2016) Interleukin-37 suppresses tumor growth through inhibition of angiogenesis in non-small cell lung cancer. J. Exp. Clin. Cancer Res. 35, 13.
    • (2016) J. Exp. Clin. Cancer Res , vol.35 , pp. 13
    • Ge, G.1    Wang, A.2    Yang, J.3    Chen, Y.4    Yang, J.5    Li, Y.6    Xue, Y.7
  • 79
  • 81
    • 84971330367 scopus 로고    scopus 로고
    • Interleukin-37 expression and its potential role in oral leukoplakia and oral squamous cell carcinoma
    • Lin, L., Wang, J., Liu, D., Liu, S., Xu, H., Ji, N., Zhou, M., Zeng, X., Zhang, D., Li, J., Chen, Q. (2016) Interleukin-37 expression and its potential role in oral leukoplakia and oral squamous cell carcinoma. Sci. Rep. 6, 26757.
    • (2016) Sci. Rep , vol.6
    • Lin, L.1    Wang, J.2    Liu, D.3    Liu, S.4    Xu, H.5    Ji, N.6    Zhou, M.7    Zeng, X.8    Zhang, D.9    Li, J.10    Chen, Q.11
  • 83
    • 79953749145 scopus 로고    scopus 로고
    • The unholy trinity: Inflammation, cytokines, and STAT3 shape the cancer microenvironment
    • Li, N., Grivennikov, S. I., Karin, M. (2011) The unholy trinity: inflammation, cytokines, and STAT3 shape the cancer microenvironment. Cancer Cell 19, 429–431.
    • (2011) Cancer Cell , vol.19 , pp. 429-431
    • Li, N.1    Grivennikov, S.I.2    Karin, M.3
  • 84
    • 84912140790 scopus 로고    scopus 로고
    • Linker phosphorylation of Smad3 promotes fibro-carcinogenesis in chronic viral hepatitis of hepatocellular carcinoma
    • Murata, M., Yoshida, K., Yamaguchi, T., Matsuzaki, K. (2014) Linker phosphorylation of Smad3 promotes fibro-carcinogenesis in chronic viral hepatitis of hepatocellular carcinoma. World J. Gastroenterol. 20, 15018–15027.
    • (2014) World J. Gastroenterol , vol.20 , pp. 15018-15027
    • Murata, M.1    Yoshida, K.2    Yamaguchi, T.3    Matsuzaki, K.4
  • 85
    • 84935012263 scopus 로고    scopus 로고
    • Introduction to the molecular basis of cancer metabolism and the Warburg effect
    • Ngo, D. C., Ververis, K., Tortorella, S. M., Karagiannis, T. C. (2015) Introduction to the molecular basis of cancer metabolism and the Warburg effect. Mol. Biol. Rep. 42, 819–823.
    • (2015) Mol. Biol. Rep , vol.42 , pp. 819-823
    • Ngo, D.C.1    Ververis, K.2    Tortorella, S.M.3    Karagiannis, T.C.4


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