Interleukin-37 reduces liver inflammatory injury via effects on hepatocytes and non-parenchymal cells

Journal of Gastroenterology and Hepatology (Australia)

Volumn 27, Issue 10, 2012, Pages 1609-1616

  Sakai, Nozomu ^a   Van Sweringen, Heather L ^a   Belizaire, Ritha M ^a   Quillin, Ralph Cutler ^a   Schuster, Rebecca ^a   Blanchard, John ^a   Burns, Justin M ^a   Tevar, Amit D ^a   Edwards, Michael J ^a   Lentsch, Alex B ^a  

^a UNIVERSITY OF CINCINNATI   (United States)

Author keywords

Chemokines; Inflammation; Liver ischemia reperfusion

Indexed keywords

ALANINE AMINOTRANSFERASE; CHEMOKINE; CYTOKINE; INTERLEUKIN 37; KERATINOCYTE CHEMOKINE; MACROPHAGE INFLAMMATORY PROTEIN 2; MYELOPEROXIDASE; PROTEIN BCL 2; REACTIVE OXYGEN METABOLITE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOACCUMULATION; BLOOD SAMPLING; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOTOXICITY; ENZYME LINKED IMMUNOSORBENT ASSAY; HEPATITIS; IN VITRO STUDY; INHIBITION KINETICS; KUPFFER CELL; LEUKOCYTE ACTIVATION; LIVER CELL; LIVER INJURY; LIVER ISCHEMIA; LIVER PROTECTION; MALE; MOUSE; NEUTROPHIL; NONHUMAN; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; REPERFUSION INJURY; WESTERN BLOTTING;

EID: 84866527284     PISSN: 08159319     EISSN: 14401746     Source Type: Journal    
DOI: 10.1111/j.1440-1746.2012.07187.x     Document Type: Article

References (26)

1. Kumar S, McDonnell PC, Lehr R etal. Identification and initial characterization of four novel members of the interleukin-1 family. J. Biol. Chem. 2000; 275: 10308-14.
2. Nold MF, Nold-Petry CA, Zepp JA, Palmer BE, Bufler P, Dinarello CA. IL-37 is a fundamental inhibitor of innate immunity. Nat. Immunol. 2010; 11: 1014-22.
3. Sharma S, Kulk N, Nold MF etal. The IL-1 family member 7b translocates to the nucleus and down-regulates proinflammatory cytokines. J. Immunol. 2008; 180: 5477-82.
4. McNamee EN, Masterson JC, Jedlicka P etal. Interleukin 37 expression protects mice from colitis. Proc. Natl. Acad. Sci. U.S.A. 2011; 108: 16711-16.
5. Racanelli V, Rehermann B. The liver as an immunological organ. Hepatology 2006; 43: S54-62.
6. Okaya T, Lentsch AB. Cytokine cascades and the hepatic inflammatory response to ischemia and reperfusion. J. Invest. Surg. 2003; 16: 141-7.
7. Jaeschke H, Smith CW. Mechanisms of neutrophil-induced parenchymal cell injury. J. Leukoc. Biol. 1997; 61: 647-53.
8. Lentsch AB, Yoshidome H, Cheadle WG, Miller FN, Edwards MJ. Chemokine involvement in hepatic ischemia/reperfusion injury in mice: roles for macrophage inflammatory protein-2 and KC. Hepatology 1998; 27: 1172-7.
9. Schierwagen C, Bylund-Fellenius AC, Lundberg C. Improved method for quantification of tissue PMN accumulation measured by myeloperoxidase activity. J. Pharmacol. Methods 1990; 23: 179-86.
10. Nauseef WM. Isolation of human neutrophils from venous blood. Methods Mol. Biol. 2007; 412: 15-20.
11. Labro MT, Ollivier V, Babin-Chevaye C. Interaction of rifalazil with oxidant-generating systems of human polymorphonuclear neutrophils. Antimicrob. Agents Chemother. 2005; 49: 5018-23.
12. Lentsch AB, Kato A, Yoshidome H, McMasters KM, Edwards MJ. Inflammatory mechanisms and therapeutic strategies for warm hepatic ischemia/reperfusion injury. Hepatology 2000; 32: 169-73.
13. Lentsch AB, Yoshidome H, Kato A etal. Requirement for interleukin-12 in the pathogenesis of warm hepatic ischemia/reperfusion injury in mice. Hepatology 1999; 30: 1448-53.
14. Colletti LM, Remick DG, Burtch GD, Kunkel SL, Strieter RM, Campbell DA Jr. Role of tumor necrosis factor-alpha in the pathophysiologic alterations after hepatic ischemia/reperfusion injury in the rat. J. Clin. Invest. 1990; 85: 1936-43.
15. Husted TL, Blanchard J, Schuster R, Shen H, Lentsch AB. Potential role for IL-23 in hepatic ischemia/reperfusion injury. Inflamm. Res. 2006; 55: 177-8.
16. Wanner GA, Ertel W, Muller P etal. Liver ischemia and reperfusion induces a systemic inflammatory response through Kupffer cell activation. Shock 1996; 5: 34-40.
17. Suzuki S, Toledo-Pereyra LH. Interleukin 1 and tumor necrosis factor production as the initial stimulants of liver ischemia and reperfusion injury. J. Surg. Res. 1994; 57: 253-8.
18. Jaeschke H, Farhood A. Neutrophil and Kupffer cell-induced oxidant stress and ischemia-reperfusion injury in rat liver. Am. J. Physiol. 1991; 260: G355-62.
19. Jaeschke H. Mechanisms of liver injury. II. Mechanisms of neutrophil-induced liver cell injury during hepatic ischemia-reperfusion and other acute inflammatory conditions. Am. J. Physiol. Gastrointest. Liver Physiol. 2006; 290: G1083-8.
20. Wu HS, Zhang JX, Wang L, Tian Y, Wang H, Rotstein O. Toll-like receptor 4 involvement in hepatic ischemia/reperfusion injury in mice. Hepatobiliary Pancreat. Dis. Int. 2004; 3: 250-3.
21. Tsung A, Hoffman RA, Izuishi K etal. Hepatic ischemia/reperfusion injury involves functional TLR4 signaling in nonparenchymal cells. J. Immunol. 2005; 175: 7661-8.
22. Kobayashi M, Takeyoshi I, Yoshinari D, Matsumoto K, Morishita Y. P38 mitogen-activated protein kinase inhibition attenuates ischemia-reperfusion injury of the rat liver. Surgery 2002; 131: 344-9.
23. Uehara T, Bennett B, Sakata ST etal. JNK mediates hepatic ischemia reperfusion injury. J. Hepatol. 2005; 42: 850-9.
24. Bilbao G, Contreras JL, Eckhoff DE etal. Reduction of ischemia-reperfusion injury of the liver by in vivo adenovirus-mediated gene transfer of the antiapoptotic Bcl-2 gene. Ann. Surg. 1999; 230: 185-93.
25. Selzner M, Rudiger HA, Selzner N, Thomas DW, Sindram D, Clavien PA. Transgenic mice overexpressing human Bcl-2 are resistant to hepatic ischemia and reperfusion. J. Hepatol. 2002; 36: 218-25.
26. Kumar S, Hanning CR, Brigham-Burke MR etal. Interleukin-1F7B (IL-1H4/IL-1F7) is processed by caspase-1 and mature IL-1F7B binds to the IL-18 receptor but does not induce IFN-gamma production. Cytokine 2002; 18: 61-71.