Searching for Hif1-α interacting proteins in renal cell carcinoma

Clinical and Translational Oncology

Volumn 14, Issue 9, 2012, Pages 698-708

  Medina Villaamil, V ^a   Aparicio Gallego, G ^a   Santamarina Cainzos I ^a   Valladares Ayerbes, M ^a   Anton Aparicio L M ^a,b  

^a CHU A Coruna   (Spain)

^b UNIVERSITY OF A CORUÑA   (Spain)

Author keywords

Angiogenesis; Biomarkers; Hif1 ; Protein interactions; Renal tumours

Indexed keywords

CARBONATE DEHYDRATASE IX; EPIDERMAL GROWTH FACTOR RECEPTOR; HYPOXIA INDUCIBLE FACTOR 1ALPHA; HYPOXIA INDUCIBLE FACTOR 1ALPHA INTERACTING PROTEIN; NOTCH1 RECEPTOR; NOTCH3 RECEPTOR; PROTEIN BCL 2; STEM CELL FACTOR RECEPTOR; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG; VASCULOTROPIN;

ADULT; AGED; ARTICLE; COHORT ANALYSIS; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; KIDNEY CARCINOMA; MAJOR CLINICAL STUDY; MALE; PROGNOSIS; PROTEIN ANALYSIS; PROTEIN EXPRESSION; TISSUE MICROARRAY;

ADULT; AGED; CARCINOMA, RENAL CELL; COHORT STUDIES; FEMALE; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; IMMUNOHISTOCHEMISTRY; KIDNEY NEOPLASMS; MALE; MIDDLE AGED; PROTEIN INTERACTION MAPPING;

EID: 84871192388     PISSN: 1699048X     EISSN: 16993055     Source Type: Journal    
DOI: 10.1007/s12094-012-0857-4     Document Type: Article

References (40)

1. Vaupel P, Mayer A (2007) Hypoxia in cancer: significance and impact on clinical outcome. Cancer Metastasis Rev 26:225-239
2. Audenet F, Yates DR, Cancel-Tassin G et al (2011) Genetic pathways involved in carcinogenesis of clear cell renal cell carcinoma: genomics towards personalized medicine. BJU Int 109:1864-1870
3. Fraga A, Ribeiro R, Medeiros R (2009) Tumor hypoxia: the role of HIF. Actas Urol Esp 33:941-951
4. Greijer AE, van der Wall E (2004) The role of hypoxia inducible factor 1 (HIF-1) in hypoxia induced apoptosis. J Clin Pathol 57:1009-1014
5. Fuhrman SA, Lasky LC, Limas C (1982) Prognostic significance of morphologic parameters in renal cell carcinoma. Am J Surg Pathol 6:655-663
6. Medina Villaamil V, Alvarez García A, Aparicio Gallego G et al (2011) Tissue array analysis for the differentiation of gliosis from gliomas. Mol Med Rep 4:451-457
7. Aranda B, Achuthan P, Alam-Faruque Y et al (2010) The IntAct molecular interaction database in 2010. Nucleic Acid Res 38:D525-D531
8. Ceol A, Aryamontri A, Licata L et al (2009) MINT, the molecular interaction database:2009 update. Nucleic Acid Res 38:D532-D539
9. Alfarano C, Andrade CE, Anthony K et al (2005) The Biomolecular Interaction Network Database and related tools 2005 update. Nucleic Acid Res 33:D418-D424
10. Hägele S, Behnam B, Borter E et al (2006) TSGA10 prevents nuclear localization of the hypoxia-inducible factor (HIF)-1alpha. FEBS Lett 580:3731-3738
11. Reddy S, Pakala S, Ohshiro K et al (2009) MicroRNA-661, a c/EBP-alpha target, inhibits metastatic tumor antigen 1 and regulates its functions. Cancer Res 69:5639-5642
12. Nordstrom-O'Brien M, van der Luijt R, van Rooijen E et al (2010) Genetic analysis of von Hippel-Lindau disease. Hum Mutat 31:521-537
13. Jeong J, Bae M, Ahn M-Y et al (2002) Regulation and destabilization of HIF-1 alpha by ARD1-mediated acetylation. Cell 111:709-720
14. Sobulo O, Borrow J, Tomek R et al (1997) MLL is fused to CBP, a histone acetyltransferase, in therapy-related acute myeloid leukemia with a t(11;16)(q23;p13.3). Proc Nat Acad Sci 94:8732-8737
15. Kamal A, Thao L, Sensintaffar J et al (2003) A high-affinity conformation of Hsp90 confers tumour selectivity on Hsp90 inhibitors. Nature 425:407-410
16. Cerchietti L, Lopes E, Yang S et al (2009) A purine scaffold Hsp90 inhibitor destabilizes BCL-6 and has specific antitumor activity in BCL-6-dependent B cell lymphomas. Nature Med 15:1369-1376
17. Deniaud E, Baguet J, Mathieu A-L et al (2006) Overexpression of Sp1 transcription factor induces apoptosis. Oncogene 25:7096-7105
18. Pause A, Lee S, Worrell R et al (1997) The von Hippel-Lindau tumor-suppressor gene product forms a stable complex with human CUL-2, a member of the Cdc53 family of proteins. Proc Nat Acad Sci 94:2156-2161
19. Hakimi M-A, Dong Y, Lane W et al (2003) A candidate X-linked mental retardation gene is a component of a new family of histone deacetylase-con- taining complexes. J Biol Chem 278:7234-7239
20. Noonan E, Place R, Pookot D et al (2009) miR-449a targets HDAC-1 and induces growth arrest in prostate cancer. Oncogene 28:1714-1724
21. Mahon P, Hirota K, Semenza G (2001) FIH-1: a novel protein that interacts with HIF-1-alpha and VHL to mediate repression of HIF-1 transcriptional activity. Genes Dev 15:2675-2686
22. Zhong H, Chiles K, Feldser D et al (2000) Modulation of hypoxia-inducible factor 1a expression by the epidermal growth factor/phosphatidylinositol 3-kinase/PTEN/AKT/FRAP pathway in human prostate cancer cells: implications for tumor angiogenesis and therapeutics. Cancer Res 60:1541-1545
23. Pantuck AJ, Zeng G, Belldegrun AS et al (2003) Pathobiology, prognosis, and targeted therapy for renal cell carcinoma: exploiting the hypoxia-induced pathway. Clin Cancer Res 9:4641-4652
24. Lidgren A, Hedberg Y, Grankvist K et al (2005) The expression of hypoxia-inducible factor 1a is a favourable independent prognostic factor in renal cell carcinoma. Clin Cancer Res 11:1129-1135
25. Rink M, Chun FK, Robinson B et al (2011) Tissue-based molecular markers for renal cell carcinoma. Minerva Urol Nefrol 63:293-308
26. Di Cristofano C, Minervini A, Menicagli M et al (2007) Nuclear expression of hypoxia-inducible factor-1alpha in clear cell renal cell carcinoma is involved in tumor progression. Am J Surg Pathol 31:1875-1881
27. Dorai T, Sawczuk I, Pastorek J et al (2006) Role of carbonic anhydrases in the progression of renal cell carcinoma subtypes: proposal of a unified hypothesis. Cancer Invest 24:754-779
28. Grabmaier K, De Weijert MCA, Verhaegh GW et al (2004) Strict regulation of CAIX (G250/MN) by Hif1-a in clear cell renal cell carcinoma. Oncogene 23:5624-5631
29. Greijer AE, van der Greijer WE (2004) The role of hypoxia inducible factor 1 (HIF-1) in hypoxia induced apoptosis. J Clin Pathol 57:1009-1014
30. Medina V, Aparicio G, Valbuena L et al (2011) Fructose transporter GLUT5 expression in clear renal cell carcinoma. Oncol Rep 25:315-323
31. Chen Y, De Marco MA, Graziani I et al (2007) Oxygen concentration determines the biological effects of NOTCH-1 signaling in adenocarcinoma of the lung. Cancer Res 67:7954-7959
32. Sahlgren C, Gustafsson MV, Jin S et al (2008) Notch signaling mediates hypoxia-induced tumor cell migration and invasion. Proc Natl Acad Sci USA 105:6392-6397
33. Bedogni B, Warneke JA, Nickoloff BJ et al (2008) Notch1 is an effector of Akt and hypoxia in melanoma development. J Clin Invest 118:3660-3670
34. Lin P, Wang W, Cai WJ et al (2009) Relationship between the expression of hypoxia-inducible factor-1alpha and epidermal growth factor receptor and micro vessel density and their clinical significance. Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 44:480-485
35. Pan CC, Chen P, Chiang H (2004) Overexpression of KIT (CD117) in chro-mophobe renal cell carcinoma and renal oncocytoma. Am J Clin Pathol 121:878-883
36. Johnson DW, Berg JN, Baldwin MA et al (1996) Mutations in the activin receptor-like kinase 1 gene in hereditary haemorrhagic telangiectasia type 2. Nat Genet 13:189-195
37. Oh SP, Seki T, Goss KA et al (2000) Activin receptor-like kinase 1 modulates transforming growth factor-beta 1 signaling in the regulation of angiogenesis. Proc Natl Acad Sci USA 97:2626-2631
38. Burrows FJ, Derbyshire EJ, Tazzari PL et al (1995) Up-regulation of endoglin on vascular endothelial cells in human solid tumors: implications for diagnosis and therapy. Clin Cancer Res 1:1623-1634
39. Goumans MJ, Valdimarsdottir G, Itoh S et al (2002) Balancing the activation state of the endothelium via two distinct TGF-beta type I receptors. EMBO J 21:1743-1753
40. Zhang X, Zhang R, Jiang Y et al (2011) The expanded human disease network combining protein-protein interaction information. Eur J Hum Genet 19:783-788