-
2
-
-
0028907874
-
A family of proteins structurally and functionally related to the E6-AP ubiquitin–protein ligase
-
2 Huibregtse, J.M., et al. A family of proteins structurally and functionally related to the E6-AP ubiquitin–protein ligase. Proc. Natl. Acad. Sci. U. S. A. 92 (1995), 2563–2567.
-
(1995)
Proc. Natl. Acad. Sci. U. S. A.
, vol.92
, pp. 2563-2567
-
-
Huibregtse, J.M.1
-
3
-
-
0033961923
-
RING for destruction?
-
3 Freemont, P.S., RING for destruction?. Curr. Biol. 10 (2000), R84–R87.
-
(2000)
Curr. Biol.
, vol.10
, pp. R84-R87
-
-
Freemont, P.S.1
-
4
-
-
0034266806
-
RING finger proteins: mediators of ubiquitin ligase activity
-
4 Joazeiro, C.A., Weissman, A.M., RING finger proteins: mediators of ubiquitin ligase activity. Cell 102 (2000), 549–552.
-
(2000)
Cell
, vol.102
, pp. 549-552
-
-
Joazeiro, C.A.1
Weissman, A.M.2
-
5
-
-
0033613222
-
RING fingers mediate ubiquitin-conjugating enzyme (E2)-dependent ubiquitination
-
5 Lorick, K.L., et al. RING fingers mediate ubiquitin-conjugating enzyme (E2)-dependent ubiquitination. Proc. Natl. Acad. Sci. U. S. A. 96 (1999), 11364–11369.
-
(1999)
Proc. Natl. Acad. Sci. U. S. A.
, vol.96
, pp. 11364-11369
-
-
Lorick, K.L.1
-
6
-
-
0034708216
-
The U box is a modified RING finger – a common domain in ubiquitination
-
6 Aravind, L., Koonin, E.V., The U box is a modified RING finger – a common domain in ubiquitination. Curr. Biol. 10 (2000), R132–R134.
-
(2000)
Curr. Biol.
, vol.10
, pp. R132-R134
-
-
Aravind, L.1
Koonin, E.V.2
-
7
-
-
0036629253
-
Protein quality control: U-box-containing E3 ubiquitin ligases join the fold
-
7 Cyr, D.M., et al. Protein quality control: U-box-containing E3 ubiquitin ligases join the fold. Trends Biochem. Sci. 27 (2002), 368–375.
-
(2002)
Trends Biochem. Sci.
, vol.27
, pp. 368-375
-
-
Cyr, D.M.1
-
8
-
-
0035980094
-
U box proteins as a new family of ubiquitin–protein ligases
-
8 Hatakeyama, S., et al. U box proteins as a new family of ubiquitin–protein ligases. J. Biol. Chem. 276 (2001), 33111–33120.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 33111-33120
-
-
Hatakeyama, S.1
-
9
-
-
3943054838
-
De-ubiquitination and ubiquitin ligase domains of A20 downregulate NF-κB signalling
-
9 Wertz, I.E., et al. De-ubiquitination and ubiquitin ligase domains of A20 downregulate NF-κB signalling. Nature 430 (2004), 694–699.
-
(2004)
Nature
, vol.430
, pp. 694-699
-
-
Wertz, I.E.1
-
10
-
-
33947727977
-
Type III secretion effectors of the IpaH family are E3 ubiquitin ligases
-
10 Rohde, J.R., et al. Type III secretion effectors of the IpaH family are E3 ubiquitin ligases. Cell Host Microbe 1 (2007), 77–83.
-
(2007)
Cell Host Microbe
, vol.1
, pp. 77-83
-
-
Rohde, J.R.1
-
11
-
-
84966350690
-
Ubiquitination independent of E1 and E2 enzymes by bacterial effectors
-
11 Qiu, J., et al. Ubiquitination independent of E1 and E2 enzymes by bacterial effectors. Nature 533 (2016), 120–124.
-
(2016)
Nature
, vol.533
, pp. 120-124
-
-
Qiu, J.1
-
12
-
-
84931031608
-
Roles of linear ubiquitinylation, a crucial regulator of NF-κB and cell death, in the immune system
-
12 Sasaki, K., Iwai, K., Roles of linear ubiquitinylation, a crucial regulator of NF-κB and cell death, in the immune system. Immunol. Rev. 266 (2015), 175–189.
-
(2015)
Immunol. Rev.
, vol.266
, pp. 175-189
-
-
Sasaki, K.1
Iwai, K.2
-
13
-
-
80054848955
-
TRIM proteins and cancer
-
13 Hatakeyama, S., TRIM proteins and cancer. Nat. Rev. Cancer 11 (2011), 792–804.
-
(2011)
Nat. Rev. Cancer
, vol.11
, pp. 792-804
-
-
Hatakeyama, S.1
-
14
-
-
84855420833
-
TRIM family: pleiotropy and diversification through homomultimer and heteromultimer formation
-
14 Napolitano, L.M., Meroni, G., TRIM family: pleiotropy and diversification through homomultimer and heteromultimer formation. IUBMB Life 64 (2012), 64–71.
-
(2012)
IUBMB Life
, vol.64
, pp. 64-71
-
-
Napolitano, L.M.1
Meroni, G.2
-
15
-
-
17744371839
-
The tripartite motif family identifies cell compartments
-
15 Reymond, A., et al. The tripartite motif family identifies cell compartments. EMBO J. 20 (2001), 2140–2151.
-
(2001)
EMBO J.
, vol.20
, pp. 2140-2151
-
-
Reymond, A.1
-
16
-
-
33646842883
-
Subclassification of the RBCC/TRIM superfamily reveals a novel motif necessary for microtubule binding
-
16 Short, K.M., Cox, T.C., Subclassification of the RBCC/TRIM superfamily reveals a novel motif necessary for microtubule binding. J. Biol. Chem. 281 (2006), 8970–8980.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 8970-8980
-
-
Short, K.M.1
Cox, T.C.2
-
17
-
-
54949126675
-
TRIM family proteins and their emerging roles in innate immunity
-
17 Ozato, K., et al. TRIM family proteins and their emerging roles in innate immunity. Nat. Rev. Immunol. 8 (2008), 849–860.
-
(2008)
Nat. Rev. Immunol.
, vol.8
, pp. 849-860
-
-
Ozato, K.1
-
18
-
-
79951669703
-
Tripartite-motif proteins and innate immune regulation
-
18 McNab, F.W., et al. Tripartite-motif proteins and innate immune regulation. Curr. Opin. Immunol. 23 (2011), 46–56.
-
(2011)
Curr. Opin. Immunol.
, vol.23
, pp. 46-56
-
-
McNab, F.W.1
-
19
-
-
79957738075
-
Transcription cofactors TRIM24, TRIM28, and TRIM33 associate to form regulatory complexes that suppress murine hepatocellular carcinoma
-
19 Herquel, B., et al. Transcription cofactors TRIM24, TRIM28, and TRIM33 associate to form regulatory complexes that suppress murine hepatocellular carcinoma. Proc. Natl. Acad. Sci. U. S. A. 108 (2011), 8212–8217.
-
(2011)
Proc. Natl. Acad. Sci. U. S. A.
, vol.108
, pp. 8212-8217
-
-
Herquel, B.1
-
20
-
-
10044249144
-
TRIMming HIV-1’s mainsail
-
20 Stevenson, M., TRIMming HIV-1’s mainsail. Nat. Immunol. 5 (2004), 355–356.
-
(2004)
Nat. Immunol.
, vol.5
, pp. 355-356
-
-
Stevenson, M.1
-
21
-
-
84971254417
-
Characterisation of assembly and ubiquitylation by the RBCC motif of Trim5α
-
21 Keown, J.R., et al. Characterisation of assembly and ubiquitylation by the RBCC motif of Trim5α. Sci. Rep., 6, 2016, 26837.
-
(2016)
Sci. Rep.
, vol.6
, pp. 26837
-
-
Keown, J.R.1
-
22
-
-
84930620950
-
Crystal structure of TRIM20 C-terminal coiled-coil/B30.2 fragment: implications for the recognition of higher order oligomers
-
22 Weinert, C., et al. Crystal structure of TRIM20 C-terminal coiled-coil/B30.2 fragment: implications for the recognition of higher order oligomers. Sci. Rep., 5, 2015, 10819.
-
(2015)
Sci. Rep.
, vol.5
, pp. 10819
-
-
Weinert, C.1
-
23
-
-
81055144784
-
Autophagy: renovation of cells and tissues
-
23 Mizushima, N., Komatsu, M., Autophagy: renovation of cells and tissues. Cell 147 (2011), 728–741.
-
(2011)
Cell
, vol.147
, pp. 728-741
-
-
Mizushima, N.1
Komatsu, M.2
-
24
-
-
36849089101
-
Homeostatic levels of p62 control cytoplasmic inclusion body formation in autophagy-deficient mice
-
24 Komatsu, M., et al. Homeostatic levels of p62 control cytoplasmic inclusion body formation in autophagy-deficient mice. Cell 131 (2007), 1149–1163.
-
(2007)
Cell
, vol.131
, pp. 1149-1163
-
-
Komatsu, M.1
-
25
-
-
84857039937
-
Autophagy as an innate immunity paradigm: expanding the scope and repertoire of pattern recognition receptors
-
25 Deretic, V., Autophagy as an innate immunity paradigm: expanding the scope and repertoire of pattern recognition receptors. Curr. Opin. Immunol. 24 (2012), 21–31.
-
(2012)
Curr. Opin. Immunol.
, vol.24
, pp. 21-31
-
-
Deretic, V.1
-
26
-
-
20644440418
-
The kinase domain of titin controls muscle gene expression and protein turnover
-
26 Lange, S., et al. The kinase domain of titin controls muscle gene expression and protein turnover. Science 308 (2005), 1599–1603.
-
(2005)
Science
, vol.308
, pp. 1599-1603
-
-
Lange, S.1
-
27
-
-
79551686189
-
Developmental regulation of MURF ubiquitin ligases and autophagy proteins nbr1, p62/SQSTM1 and LC3 during cardiac myofibril assembly and turnover
-
27 Perera, S., et al. Developmental regulation of MURF ubiquitin ligases and autophagy proteins nbr1, p62/SQSTM1 and LC3 during cardiac myofibril assembly and turnover. Dev. Biol. 351 (2011), 46–61.
-
(2011)
Dev. Biol.
, vol.351
, pp. 46-61
-
-
Perera, S.1
-
28
-
-
84885050987
-
MURF2B, a novel LC3-binding protein, participates with MURF2A in the switch between autophagy and ubiquitin proteasome system during differentiation of C2C12 muscle cells
-
28 Pizon, V., et al. MURF2B, a novel LC3-binding protein, participates with MURF2A in the switch between autophagy and ubiquitin proteasome system during differentiation of C2C12 muscle cells. PLoS One, 8, 2013, e76140.
-
(2013)
PLoS One
, vol.8
, pp. e76140
-
-
Pizon, V.1
-
29
-
-
84894459149
-
Role of autophagy, SQSTM1, SH3GLB1, and TRIM63 in the turnover of nicotinic acetylcholine receptors
-
29 Khan, M.M., et al. Role of autophagy, SQSTM1, SH3GLB1, and TRIM63 in the turnover of nicotinic acetylcholine receptors. Autophagy 10 (2014), 123–136.
-
(2014)
Autophagy
, vol.10
, pp. 123-136
-
-
Khan, M.M.1
-
30
-
-
77955427514
-
Downregulation of active IKK beta by Ro52-mediated autophagy
-
30 Niida, M., et al. Downregulation of active IKK beta by Ro52-mediated autophagy. Mol. Immunol. 47 (2010), 2378–2387.
-
(2010)
Mol. Immunol.
, vol.47
, pp. 2378-2387
-
-
Niida, M.1
-
31
-
-
84862791627
-
TRIM13 regulates ER stress induced autophagy and clonogenic ability of the cells
-
31 Tomar, D., et al. TRIM13 regulates ER stress induced autophagy and clonogenic ability of the cells. Biochim. Biophys. Acta 1823 (2012), 316–326.
-
(2012)
Biochim. Biophys. Acta
, vol.1823
, pp. 316-326
-
-
Tomar, D.1
-
32
-
-
84876341593
-
A KRAB/KAP1–miRNA cascade regulates erythropoiesis through stage-specific control of mitophagy
-
32 Barde, I., et al. A KRAB/KAP1–miRNA cascade regulates erythropoiesis through stage-specific control of mitophagy. Science 340 (2013), 350–353.
-
(2013)
Science
, vol.340
, pp. 350-353
-
-
Barde, I.1
-
33
-
-
84876865718
-
Acetylated hsp70 and KAP1-mediated Vps34 SUMOylation is required for autophagosome creation in autophagy
-
33 Yang, Y., et al. Acetylated hsp70 and KAP1-mediated Vps34 SUMOylation is required for autophagosome creation in autophagy. Proc. Natl Acad. Sci. U. S. A. 110 (2013), 6841–6846.
-
(2013)
Proc. Natl Acad. Sci. U. S. A.
, vol.110
, pp. 6841-6846
-
-
Yang, Y.1
-
34
-
-
84907599058
-
TRIM proteins regulate autophagy and can target autophagic substrates by direct recognition
-
34 Mandell, M.A., et al. TRIM proteins regulate autophagy and can target autophagic substrates by direct recognition. Dev. Cell 30 (2014), 394–409.
-
(2014)
Dev. Cell
, vol.30
, pp. 394-409
-
-
Mandell, M.A.1
-
35
-
-
84960354182
-
Precision autophagy directed by receptor regulators – emerging examples within the TRIM family
-
35 Kimura, T., et al. Precision autophagy directed by receptor regulators – emerging examples within the TRIM family. J. Cell Sci. 129 (2016), 881–891.
-
(2016)
J. Cell Sci.
, vol.129
, pp. 881-891
-
-
Kimura, T.1
-
36
-
-
84960432718
-
TRIM-mediated precision autophagy targets cytoplasmic regulators of innate immunity
-
36 Kimura, T., et al. TRIM-mediated precision autophagy targets cytoplasmic regulators of innate immunity. J. Cell Biol. 210 (2015), 973–989.
-
(2015)
J. Cell Biol.
, vol.210
, pp. 973-989
-
-
Kimura, T.1
-
37
-
-
84961115720
-
Ubiquitin in the activation and attenuation of innate antiviral immunity
-
37 Heaton, S.M., et al. Ubiquitin in the activation and attenuation of innate antiviral immunity. J. Exp. Med. 213 (2016), 1–13.
-
(2016)
J. Exp. Med.
, vol.213
, pp. 1-13
-
-
Heaton, S.M.1
-
38
-
-
84859496523
-
TRIM5 structure, HIV-1 capsid recognition, and innate immune signaling
-
38 Grutter, M.G., Luban, J., TRIM5 structure, HIV-1 capsid recognition, and innate immune signaling. Curr. Opin. Virol. 2 (2012), 142–150.
-
(2012)
Curr. Opin. Virol.
, vol.2
, pp. 142-150
-
-
Grutter, M.G.1
Luban, J.2
-
39
-
-
65549164536
-
Influenza A virus NS1 targets the ubiquitin ligase TRIM25 to evade recognition by the host viral RNA sensor RIG-I
-
39 Gack, M.U., et al. Influenza A virus NS1 targets the ubiquitin ligase TRIM25 to evade recognition by the host viral RNA sensor RIG-I. Cell Host Microbe 5 (2009), 439–449.
-
(2009)
Cell Host Microbe
, vol.5
, pp. 439-449
-
-
Gack, M.U.1
-
40
-
-
84870820660
-
Species-specific inhibition of RIG-I ubiquitination and IFN induction by the influenza A virus NS1 protein
-
40 Rajsbaum, R., et al. Species-specific inhibition of RIG-I ubiquitination and IFN induction by the influenza A virus NS1 protein. PLoS Pathog., 8, 2012, e1003059.
-
(2012)
PLoS Pathog.
, vol.8
, pp. e1003059
-
-
Rajsbaum, R.1
-
41
-
-
84907700872
-
The interferon signaling antagonist function of yellow fever virus NS5 protein is activated by type I interferon
-
41 Laurent-Rolle, M., The interferon signaling antagonist function of yellow fever virus NS5 protein is activated by type I interferon. Cell Host Microbe 16 (2014), 314–327.
-
(2014)
Cell Host Microbe
, vol.16
, pp. 314-327
-
-
Laurent-Rolle, M.1
-
42
-
-
84881030086
-
Viral evasion mechanisms of early antiviral responses involving regulation of ubiquitin pathways
-
42 Rajsbaum, R., Garcia-Sastre, A., Viral evasion mechanisms of early antiviral responses involving regulation of ubiquitin pathways. Trends Microbiol. 21 (2013), 421–429.
-
(2013)
Trends Microbiol.
, vol.21
, pp. 421-429
-
-
Rajsbaum, R.1
Garcia-Sastre, A.2
-
43
-
-
84908267694
-
InTRIMsic immunity: positive and negative regulation of immune signaling by tripartite motif proteins
-
43 Versteeg, G.A., et al. InTRIMsic immunity: positive and negative regulation of immune signaling by tripartite motif proteins. Cytokine Growth Factor Rev. 25 (2014), 563–576.
-
(2014)
Cytokine Growth Factor Rev.
, vol.25
, pp. 563-576
-
-
Versteeg, G.A.1
-
44
-
-
84903647409
-
Unanchored K48-linked polyubiquitin synthesized by the E3-ubiquitin ligase TRIM6 stimulates the interferon–IKKε kinase-mediated antiviral response
-
44 Rajsbaum, R., et al. Unanchored K48-linked polyubiquitin synthesized by the E3-ubiquitin ligase TRIM6 stimulates the interferon–IKKε kinase-mediated antiviral response. Immunity 40 (2014), 880–895.
-
(2014)
Immunity
, vol.40
, pp. 880-895
-
-
Rajsbaum, R.1
-
45
-
-
84989917334
-
The Matrix Protein of Nipah Virus Targets the E3-Ubiquitin Ligase TRIM6 to Inhibit the IKKε Kinase-Mediated Type-I IFN Antiviral Response
-
45 Bharaj, P., et al. The Matrix Protein of Nipah Virus Targets the E3-Ubiquitin Ligase TRIM6 to Inhibit the IKKε Kinase-Mediated Type-I IFN Antiviral Response. PLoS Pathog, 12, 2016, e1005880.
-
(2016)
PLoS Pathog
, vol.12
, pp. e1005880
-
-
Bharaj, P.1
-
46
-
-
0037020175
-
TRIM8/GERP RING finger protein interacts with SOCS-1
-
46 Toniato, E., et al. TRIM8/GERP RING finger protein interacts with SOCS-1. J. Biol. Chem. 277 (2002), 37315–37322.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 37315-37322
-
-
Toniato, E.1
-
47
-
-
77954364837
-
TRIM8 modulates STAT3 activity through negative regulation of PIAS3
-
47 Okumura, F., et al. TRIM8 modulates STAT3 activity through negative regulation of PIAS3. J. Cell Sci. 123 (2010), 2238–2245.
-
(2010)
J. Cell Sci.
, vol.123
, pp. 2238-2245
-
-
Okumura, F.1
-
48
-
-
79955377543
-
TRIM5 is an innate immune sensor for the retrovirus capsid lattice
-
48 Pertel, T., et al. TRIM5 is an innate immune sensor for the retrovirus capsid lattice. Nature 472 (2011), 361–365.
-
(2011)
Nature
, vol.472
, pp. 361-365
-
-
Pertel, T.1
-
49
-
-
84863229333
-
E3 ubiquitin ligase tripartite motif 38 negatively regulates TLR-mediated immune responses by proteasomal degradation of TNF receptor-associated factor 6 in macrophages
-
49 Zhao, W., et al. E3 ubiquitin ligase tripartite motif 38 negatively regulates TLR-mediated immune responses by proteasomal degradation of TNF receptor-associated factor 6 in macrophages. J. Immunol. 188 (2012), 2567–2574.
-
(2012)
J. Immunol.
, vol.188
, pp. 2567-2574
-
-
Zhao, W.1
-
50
-
-
84893393844
-
TRIM38 inhibits TNFα- and IL-1β-triggered NF-κB activation by mediating lysosome-dependent degradation of TAB2/3
-
50 Hu, M.M., et al. TRIM38 inhibits TNFα- and IL-1β-triggered NF-κB activation by mediating lysosome-dependent degradation of TAB2/3. Proc. Natl. Acad. Sci. U. S. A. 111 (2014), 1509–1514.
-
(2014)
Proc. Natl. Acad. Sci. U. S. A.
, vol.111
, pp. 1509-1514
-
-
Hu, M.M.1
-
51
-
-
84945156921
-
TRIM38 negatively regulates TLR3/4-mediated innate immune and inflammatory responses by two sequential and distinct mechanisms
-
51 Hu, M.M., et al. TRIM38 negatively regulates TLR3/4-mediated innate immune and inflammatory responses by two sequential and distinct mechanisms. J. Immunol. 195 (2015), 4415–4425.
-
(2015)
J. Immunol.
, vol.195
, pp. 4415-4425
-
-
Hu, M.M.1
-
52
-
-
64049092850
-
Identification of TRIM23 as a cofactor involved in the regulation of NF-κB by human cytomegalovirus
-
52 Poole, E., et al. Identification of TRIM23 as a cofactor involved in the regulation of NF-κB by human cytomegalovirus. J. Virol. 83 (2009), 3581–3590.
-
(2009)
J. Virol.
, vol.83
, pp. 3581-3590
-
-
Poole, E.1
-
53
-
-
84871946152
-
TRIM protein-mediated regulation of inflammatory and innate immune signaling and its association with antiretroviral activity
-
53 Uchil, P.D., et al. TRIM protein-mediated regulation of inflammatory and innate immune signaling and its association with antiretroviral activity. J. Virol. 87 (2013), 257–272.
-
(2013)
J. Virol.
, vol.87
, pp. 257-272
-
-
Uchil, P.D.1
-
54
-
-
84881475510
-
TRIM22 inhibits the TRAF6-stimulated NF-κB pathway by targeting TAB2 for degradation
-
54 Qiu, H., et al. TRIM22 inhibits the TRAF6-stimulated NF-κB pathway by targeting TAB2 for degradation. Virol. Sin. 28 (2013), 209–215.
-
(2013)
Virol. Sin.
, vol.28
, pp. 209-215
-
-
Qiu, H.1
-
55
-
-
82755190610
-
Tripartite motif 8 (TRIM8) modulates TNFα- and IL-1β-triggered NF-κB activation by targeting TAK1 for K63-linked polyubiquitination
-
55 Li, Q., et al. Tripartite motif 8 (TRIM8) modulates TNFα- and IL-1β-triggered NF-κB activation by targeting TAK1 for K63-linked polyubiquitination. Proc. Natl Acad. Sci. U. S. A. 108 (2011), 19341–19346.
-
(2011)
Proc. Natl Acad. Sci. U. S. A.
, vol.108
, pp. 19341-19346
-
-
Li, Q.1
-
56
-
-
40949163764
-
TRIM30α negatively regulates TLR-mediated NF-κB activation by targeting TAB2 and TAB3 for degradation
-
56 Shi, M., et al. TRIM30α negatively regulates TLR-mediated NF-κB activation by targeting TAB2 and TAB3 for degradation. Nat. Immunol. 9 (2008), 369–377.
-
(2008)
Nat. Immunol.
, vol.9
, pp. 369-377
-
-
Shi, M.1
-
57
-
-
77957677615
-
Polyubiquitin conjugation to NEMO by triparite motif protein 23 (TRIM23) is critical in antiviral defense
-
57 Arimoto, K., et al. Polyubiquitin conjugation to NEMO by triparite motif protein 23 (TRIM23) is critical in antiviral defense. Proc. Natl Acad. Sci. U. S. A. 107 (2010), 15856–15861.
-
(2010)
Proc. Natl Acad. Sci. U. S. A.
, vol.107
, pp. 15856-15861
-
-
Arimoto, K.1
-
58
-
-
30744475939
-
The Ret finger protein inhibits signaling mediated by the noncanonical and canonical IκB kinase family members
-
58 Zha, J., et al. The Ret finger protein inhibits signaling mediated by the noncanonical and canonical IκB kinase family members. J. Immunol. 176 (2006), 1072–1080.
-
(2006)
J. Immunol.
, vol.176
, pp. 1072-1080
-
-
Zha, J.1
-
59
-
-
79960063338
-
TRIM40 promotes neddylation of IKKγ and is downregulated in gastrointestinal cancers
-
59 Noguchi, K., et al. TRIM40 promotes neddylation of IKKγ and is downregulated in gastrointestinal cancers. Carcinogenesis 32 (2011), 995–1004.
-
(2011)
Carcinogenesis
, vol.32
, pp. 995-1004
-
-
Noguchi, K.1
-
60
-
-
84920285386
-
Negative regulation of NF-κB activity by brain-specific TRIpartite motif protein 9
-
60 Shi, M., et al. Negative regulation of NF-κB activity by brain-specific TRIpartite motif protein 9. Nat. Commun., 5, 2014, 4820.
-
(2014)
Nat. Commun.
, vol.5
, pp. 4820
-
-
Shi, M.1
-
61
-
-
52649104806
-
The familial Mediterranean fever protein, pyrin, is cleaved by caspase-1 and activates NF-κB through its N-terminal fragment
-
61 Chae, J.J., et al. The familial Mediterranean fever protein, pyrin, is cleaved by caspase-1 and activates NF-κB through its N-terminal fragment. Blood 112 (2008), 1794–1803.
-
(2008)
Blood
, vol.112
, pp. 1794-1803
-
-
Chae, J.J.1
-
62
-
-
84869020774
-
Nucleo-cytoplasmic trafficking of TRIM8, a novel oncogene, is involved in positive regulation of TNF induced NF-κB pathway
-
62 Tomar, D., et al. Nucleo-cytoplasmic trafficking of TRIM8, a novel oncogene, is involved in positive regulation of TNF induced NF-κB pathway. PLoS One, 7, 2012, e48662.
-
(2012)
PLoS One
, vol.7
, pp. e48662
-
-
Tomar, D.1
-
63
-
-
0038146926
-
Promyelocytic leukemia protein sensitizes tumor necrosis factor alpha-induced apoptosis by inhibiting the NF-κB survival pathway
-
63 Wu, W.S., et al. Promyelocytic leukemia protein sensitizes tumor necrosis factor alpha-induced apoptosis by inhibiting the NF-κB survival pathway. J. Biol. Chem. 278 (2003), 12294–12304.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 12294-12304
-
-
Wu, W.S.1
-
64
-
-
84957437968
-
TRIM39 negatively regulates the NFκB-mediated signaling pathway through stabilization of Cactin
-
64 Suzuki, M., et al. TRIM39 negatively regulates the NFκB-mediated signaling pathway through stabilization of Cactin. Cell. Mol. Life Sci. 73 (2016), 1085–1101.
-
(2016)
Cell. Mol. Life Sci.
, vol.73
, pp. 1085-1101
-
-
Suzuki, M.1
-
65
-
-
84862706169
-
TRIM45 negatively regulates NF-κB-mediated transcription and suppresses cell proliferation
-
65 Shibata, M., et al. TRIM45 negatively regulates NF-κB-mediated transcription and suppresses cell proliferation. Biochem. Biophys. Res. Commun. 423 (2012), 104–109.
-
(2012)
Biochem. Biophys. Res. Commun.
, vol.423
, pp. 104-109
-
-
Shibata, M.1
-
66
-
-
84867801015
-
TRIM56 is an essential component of the TLR3 antiviral signaling pathway
-
66 Shen, Y., et al. TRIM56 is an essential component of the TLR3 antiviral signaling pathway. J. Biol. Chem. 287 (2012), 36404–36413.
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 36404-36413
-
-
Shen, Y.1
-
67
-
-
84872683702
-
The E3 ubiquitin ligase TRIM21 negatively regulates the innate immune response to intracellular double-stranded DNA
-
67 Zhang, Z., et al. The E3 ubiquitin ligase TRIM21 negatively regulates the innate immune response to intracellular double-stranded DNA. Nat. Immunol. 14 (2013), 172–178.
-
(2013)
Nat. Immunol.
, vol.14
, pp. 172-178
-
-
Zhang, Z.1
-
68
-
-
78650214109
-
The ubiquitin ligase TRIM56 regulates innate immune responses to intracellular double-stranded DNA
-
68 Tsuchida, T., et al. The ubiquitin ligase TRIM56 regulates innate immune responses to intracellular double-stranded DNA. Immunity 33 (2010), 765–776.
-
(2010)
Immunity
, vol.33
, pp. 765-776
-
-
Tsuchida, T.1
-
69
-
-
84906344488
-
TRIM13 is a negative regulator of MDA5-mediated type I interferon production
-
69 Narayan, K., et al. TRIM13 is a negative regulator of MDA5-mediated type I interferon production. J. Viro. 88 (2014), 10748–10757.
-
(2014)
J. Viro.
, vol.88
, pp. 10748-10757
-
-
Narayan, K.1
-
70
-
-
84892606477
-
TRIM14 is a mitochondrial adaptor that facilitates retinoic acid-inducible gene-I-like receptor-mediated innate immune response
-
70 Zhou, Z., et al. TRIM14 is a mitochondrial adaptor that facilitates retinoic acid-inducible gene-I-like receptor-mediated innate immune response. Proc. Natl Acad. Sci. U. S. A. 111 (2014), E245–E254.
-
(2014)
Proc. Natl Acad. Sci. U. S. A.
, vol.111
, pp. E245-E254
-
-
Zhou, Z.1
-
71
-
-
84875468205
-
Novel function of Trim44 promotes an antiviral response by stabilizing VISA
-
71 Yang, B., et al. Novel function of Trim44 promotes an antiviral response by stabilizing VISA. J. Immunol. 190 (2013), 3613–3619.
-
(2013)
J. Immunol.
, vol.190
, pp. 3613-3619
-
-
Yang, B.1
-
72
-
-
84861951738
-
TRIM59 interacts with ECSIT and negatively regulates NF-κB and IRF-3/7-mediated signal pathways
-
72 Kondo, T., et al. TRIM59 interacts with ECSIT and negatively regulates NF-κB and IRF-3/7-mediated signal pathways. Biochem. Biophys. Res. Commun. 422 (2012), 501–507.
-
(2012)
Biochem. Biophys. Res. Commun.
, vol.422
, pp. 501-507
-
-
Kondo, T.1
-
73
-
-
84877650680
-
TRIM11 negatively regulates IFNβ production and antiviral activity by targeting TBK1
-
73 Lee, Y., et al. TRIM11 negatively regulates IFNβ production and antiviral activity by targeting TBK1. PLoS One, 8, 2013, e63255.
-
(2013)
PLoS One
, vol.8
, pp. e63255
-
-
Lee, Y.1
-
74
-
-
84862102052
-
Tripartite motif-containing protein 38 negatively regulates TLR3/4- and RIG-I-mediated IFN-β production and antiviral response by targeting NAP1
-
74 Zhao, W., et al. Tripartite motif-containing protein 38 negatively regulates TLR3/4- and RIG-I-mediated IFN-β production and antiviral response by targeting NAP1. J. Immunol. 188 (2012), 5311–5318.
-
(2012)
J. Immunol.
, vol.188
, pp. 5311-5318
-
-
Zhao, W.1
-
75
-
-
84904364644
-
TRIM68 negatively regulates IFN-β production by degrading TRK fused gene, a novel driver of IFN-β downstream of anti-viral detection systems
-
75 Wynne, C., et al. TRIM68 negatively regulates IFN-β production by degrading TRK fused gene, a novel driver of IFN-β downstream of anti-viral detection systems. PLoS One, 9, 2014, e101503.
-
(2014)
PLoS One
, vol.9
, pp. e101503
-
-
Wynne, C.1
-
76
-
-
49649125136
-
The E3 ubiquitin ligase Ro52 negatively regulates IFN-β production post-pathogen recognition by polyubiquitin-mediated degradation of IRF3
-
76 Higgs, R., et al. The E3 ubiquitin ligase Ro52 negatively regulates IFN-β production post-pathogen recognition by polyubiquitin-mediated degradation of IRF3. J. Immunol. 181 (2008), 1780–1786.
-
(2008)
J. Immunol.
, vol.181
, pp. 1780-1786
-
-
Higgs, R.1
-
77
-
-
84905484363
-
TRIpartite motif 21 (TRIM21) differentially regulates the stability of interferon regulatory factor 5 (IRF5) isoforms
-
77 Lazzari, E., et al. TRIpartite motif 21 (TRIM21) differentially regulates the stability of interferon regulatory factor 5 (IRF5) isoforms. PLoS One, 9, 2014, e103609.
-
(2014)
PLoS One
, vol.9
, pp. e103609
-
-
Lazzari, E.1
-
78
-
-
80555133291
-
Tripartite motif-containing protein 28 is a small ubiquitin-related modifier E3 ligase and negative regulator of IFN regulatory factor 7
-
78 Liang, Q., et al. Tripartite motif-containing protein 28 is a small ubiquitin-related modifier E3 ligase and negative regulator of IFN regulatory factor 7. J. Immunol. 187 (2011), 4754–4763.
-
(2011)
J. Immunol.
, vol.187
, pp. 4754-4763
-
-
Liang, Q.1
-
79
-
-
84874256730
-
The E3-ligase TRIM family of proteins regulates signaling pathways triggered by innate immune pattern-recognition receptors
-
79 Versteeg, G.A., et al. The E3-ligase TRIM family of proteins regulates signaling pathways triggered by innate immune pattern-recognition receptors. Immunity 38 (2013), 384–398.
-
(2013)
Immunity
, vol.38
, pp. 384-398
-
-
Versteeg, G.A.1
-
80
-
-
84920415711
-
The role for autophagy in cancer
-
80 White, E., The role for autophagy in cancer. J. Clin. Invest. 125 (2015), 42–46.
-
(2015)
J. Clin. Invest.
, vol.125
, pp. 42-46
-
-
White, E.1
-
81
-
-
3843094070
-
Therapeutic cancer vaccines
-
81 Acres, B., et al. Therapeutic cancer vaccines. Curr. Opin. Mol. Ther. 6 (2004), 40–47.
-
(2004)
Curr. Opin. Mol. Ther.
, vol.6
, pp. 40-47
-
-
Acres, B.1
-
82
-
-
84878904155
-
TRIM proteins in cancer
-
82 Cambiaghi, V., et al. TRIM proteins in cancer. Adv. Exp. Med. Biol. 770 (2012), 77–91.
-
(2012)
Adv. Exp. Med. Biol.
, vol.770
, pp. 77-91
-
-
Cambiaghi, V.1
-
83
-
-
67650895889
-
Trim24 targets endogenous p53 for degradation
-
83 Allton, K., et al. Trim24 targets endogenous p53 for degradation. Proc. Natl Acad. Sci. U. S. A. 106 (2009), 11612–11616.
-
(2009)
Proc. Natl Acad. Sci. U. S. A.
, vol.106
, pp. 11612-11616
-
-
Allton, K.1
-
84
-
-
0029030016
-
The N-terminal part of TIF1, a putative mediator of the ligand-dependent activation function (AF-2) of nuclear receptors, is fused to B-raf in the oncogenic protein T18
-
84 Le Douarin, B., et al. The N-terminal part of TIF1, a putative mediator of the ligand-dependent activation function (AF-2) of nuclear receptors, is fused to B-raf in the oncogenic protein T18. EMBO J. 14 (1995), 2020–2033.
-
(1995)
EMBO J.
, vol.14
, pp. 2020-2033
-
-
Le Douarin, B.1
-
85
-
-
36549086517
-
Loss of Trim24 (Tif1α) gene function confers oncogenic activity to retinoic acid receptor alpha
-
85 Khetchoumian, K., et al. Loss of Trim24 (Tif1α) gene function confers oncogenic activity to retinoic acid receptor alpha. Nat. Genet. 39 (2007), 1500–1506.
-
(2007)
Nat. Genet.
, vol.39
, pp. 1500-1506
-
-
Khetchoumian, K.1
-
86
-
-
71749116424
-
TRIM24 mediates ligand-dependent activation of androgen receptor and is repressed by a bromodomain-containing protein, BRD7, in prostate cancer cells
-
86 Kikuchi, M., et al. TRIM24 mediates ligand-dependent activation of androgen receptor and is repressed by a bromodomain-containing protein, BRD7, in prostate cancer cells. Biochim. Biophys. Acta 1793 (2009), 1828–1836.
-
(2009)
Biochim. Biophys. Acta
, vol.1793
, pp. 1828-1836
-
-
Kikuchi, M.1
-
87
-
-
84969793941
-
TRIM24 is an oncogenic transcriptional activator in prostate cancer
-
87 Groner, A.C., et al. TRIM24 is an oncogenic transcriptional activator in prostate cancer. Cancer Cell 29 (2016), 846–858.
-
(2016)
Cancer Cell
, vol.29
, pp. 846-858
-
-
Groner, A.C.1
-
88
-
-
35449006644
-
MAGE-A, mMage-b, and MAGE-C proteins form complexes with KAP1 and suppress p53-dependent apoptosis in MAGE-positive cell lines
-
88 Yang, B., et al. MAGE-A, mMage-b, and MAGE-C proteins form complexes with KAP1 and suppress p53-dependent apoptosis in MAGE-positive cell lines. Cancer Res. 67 (2007), 9954–9962.
-
(2007)
Cancer Res.
, vol.67
, pp. 9954-9962
-
-
Yang, B.1
-
89
-
-
84943796824
-
Oncogenic MAGEA–TRIM28 ubiquitin ligase downregulates autophagy by ubiquitinating and degrading AMPK in cancer
-
89 Pineda, C.T., Potts, P.R., Oncogenic MAGEA–TRIM28 ubiquitin ligase downregulates autophagy by ubiquitinating and degrading AMPK in cancer. Autophagy 11 (2015), 844–846.
-
(2015)
Autophagy
, vol.11
, pp. 844-846
-
-
Pineda, C.T.1
Potts, P.R.2
-
90
-
-
84922689340
-
Degradation of AMPK by a cancer-specific ubiquitin ligase
-
90 Pineda, C.T., et al. Degradation of AMPK by a cancer-specific ubiquitin ligase. Cell 160 (2015), 715–728.
-
(2015)
Cell
, vol.160
, pp. 715-728
-
-
Pineda, C.T.1
-
91
-
-
84904068372
-
TRIM29 as a novel prostate basal cell marker for diagnosis of prostate cancer
-
91 Kanno, Y., et al. TRIM29 as a novel prostate basal cell marker for diagnosis of prostate cancer. Acta Histochem. 116 (2014), 708–712.
-
(2014)
Acta Histochem.
, vol.116
, pp. 708-712
-
-
Kanno, Y.1
-
92
-
-
77953416244
-
The ATDC (TRIM29) protein binds p53 and antagonizes p53-mediated functions
-
92 Yuan, Z., et al. The ATDC (TRIM29) protein binds p53 and antagonizes p53-mediated functions. Mol. Cell. Biol. 30 (2010), 3004–3015.
-
(2010)
Mol. Cell. Biol.
, vol.30
, pp. 3004-3015
-
-
Yuan, Z.1
-
93
-
-
84946606368
-
ATDC (ataxia telangiectasia group D complementing) promotes radioresistance through an interaction with the RNF8 ubiquitin ligase
-
93 Yang, H., et al. ATDC (ataxia telangiectasia group D complementing) promotes radioresistance through an interaction with the RNF8 ubiquitin ligase. J. Biol. Chem. 290 (2015), 27146–27157.
-
(2015)
J. Biol. Chem.
, vol.290
, pp. 27146-27157
-
-
Yang, H.1
-
94
-
-
84934963416
-
TRIM29 regulates the assembly of DNA repair proteins into damaged chromatin
-
94 Masuda, Y., et al. TRIM29 regulates the assembly of DNA repair proteins into damaged chromatin. Nat. Commun., 6, 2015, 7299.
-
(2015)
Nat. Commun.
, vol.6
, pp. 7299
-
-
Masuda, Y.1
-
95
-
-
84907048357
-
TRIM29 suppresses TWIST1 and invasive breast cancer behavior
-
95 Ai, L., et al. TRIM29 suppresses TWIST1 and invasive breast cancer behavior. Cancer Res. 74 (2014), 4875–4887.
-
(2014)
Cancer Res.
, vol.74
, pp. 4875-4887
-
-
Ai, L.1
-
96
-
-
85006483271
-
Dedicated SNAREs and specialized TRIM cargo receptors mediate secretory autophagy
-
96 Kimura, T., et al. Dedicated SNAREs and specialized TRIM cargo receptors mediate secretory autophagy. EMBO J 36 (2017), 42–60.
-
(2017)
EMBO J
, vol.36
, pp. 42-60
-
-
Kimura, T.1
|