Polyubiquitin conjugation to NEMO by triparite motif protein 23 (TRIM23) is critical in antiviral defense

Proceedings of the National Academy of Sciences of the United States of America

Volumn 107, Issue 36, 2010, Pages 15856-15861

  Arimoto, Kei Ichiro ^a   Funami, Kenji ^b   Saeki, Yasushi ^c   Tanaka, Keiji ^c   Okawa, Katsuya ^d   Takeuchi, Osamu ^e   Akira, Shizuo ^e   Murakami, Yoshiki ^a   Shimotohno, Kunitada ^b  

^a KYOTO UNIVERSITY   (Japan)

^b CHIBA INSTITUTE OF TECHNOLOGY   (Japan)

^c TOKYO METROPOLITAN INSTITUTE OF MEDICAL SCIENCE   (Japan)

^d KYOWA HAKKO KOGYO CO LTD   (Japan)

^e OSAKA UNIVERSITY   (Japan)

Author keywords

Innate immunity; Signal transduction; Virus infection

Indexed keywords

ARGININE; I KAPPA B KINASE GAMMA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERFERON; INTERFERON REGULATORY FACTOR 3; LYSINE; POLYUBIQUITIN; PROTEIN TRIM23; TUMOR NECROSIS FACTOR ALPHA; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG; GUANINE NUCLEOTIDE BINDING PROTEIN; I KAPPA B KINASE; IKBKG PROTEIN, HUMAN; TRIM23 PROTEIN, HUMAN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIVIRAL ACTIVITY; ARTICLE; CELL ACTIVATION; CONJUGATION; CONTROLLED STUDY; EMBRYO CELL; ENZYME ACTIVATION; FIBROBLAST; GENE EXPRESSION; HOST RESISTANCE; HUMAN; HUMAN CELL; INNATE IMMUNITY; MEDIATOR; MOUSE; MUTANT; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; REPORTER GENE; SENDAI VIRUS; SENDAI VIRUS INFECTION; SERUM RESPONSIVE ELEMENT; UBIQUITINATION; VIRUS; WILD TYPE; CELL LINE; GENE SILENCING; METABOLISM;

CELL LINE; GENE KNOCKDOWN TECHNIQUES; GTP-BINDING PROTEINS; HUMANS; I-KAPPA B KINASE; POLYUBIQUITIN;

EID: 77957677615     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1004621107     Document Type: Article

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