-
1
-
-
79956115511
-
Distinct mechanisms of ferritin delivery to lysosomes in iron-depleted and iron-replete cells
-
Asano T, Komatsu M, Yamaguchi-Iwai Y, Ishikawa F, Mizushima N, Iwai K (2011) Distinct mechanisms of ferritin delivery to lysosomes in iron-depleted and iron-replete cells. Mol Cell Biol 31: 2040–2052
-
(2011)
Mol Cell Biol
, vol.31
, pp. 2040-2052
-
-
Asano, T.1
Komatsu, M.2
Yamaguchi-Iwai, Y.3
Ishikawa, F.4
Mizushima, N.5
Iwai, K.6
-
2
-
-
50249084987
-
Autophagosome formation from membrane compartments enriched in phosphatidylinositol 3-phosphate and dynamically connected to the endoplasmic reticulum
-
Axe EL, Walker SA, Manifava M, Chandra P, Roderick HL, Habermann A, Griffiths G, Ktistakis NT (2008) Autophagosome formation from membrane compartments enriched in phosphatidylinositol 3-phosphate and dynamically connected to the endoplasmic reticulum. J Cell Biol 182: 685–701
-
(2008)
J Cell Biol
, vol.182
, pp. 685-701
-
-
Axe, E.L.1
Walker, S.A.2
Manifava, M.3
Chandra, P.4
Roderick, H.L.5
Habermann, A.6
Griffiths, G.7
Ktistakis, N.T.8
-
3
-
-
15244340169
-
Differential use of endoplasmic reticulum membrane for phagocytosis in J774 macrophages
-
Becker T, Volchuk A, Rothman JE (2005) Differential use of endoplasmic reticulum membrane for phagocytosis in J774 macrophages. Proc Natl Acad Sci USA 102: 4022–4026
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 4022-4026
-
-
Becker, T.1
Volchuk, A.2
Rothman, J.E.3
-
4
-
-
84883414890
-
The LIR motif – crucial for selective autophagy
-
Birgisdottir AB, Lamark T, Johansen T (2013) The LIR motif – crucial for selective autophagy. J Cell Sci 126: 3237–3247
-
(2013)
J Cell Sci
, vol.126
, pp. 3237-3247
-
-
Birgisdottir, A.B.1
Lamark, T.2
Johansen, T.3
-
5
-
-
27944504351
-
p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death
-
Bjorkoy G, Lamark T, Brech A, Outzen H, Perander M, Overvatn A, Stenmark H, Johansen T (2005) p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death. J Cell Biol 171: 603–614
-
(2005)
J Cell Biol
, vol.171
, pp. 603-614
-
-
Bjorkoy, G.1
Lamark, T.2
Brech, A.3
Outzen, H.4
Perander, M.5
Overvatn, A.6
Stenmark, H.7
Johansen, T.8
-
6
-
-
83255188884
-
Sec22b regulates phagosomal maturation and antigen crosspresentation by dendritic cells
-
Cebrian I, Visentin G, Blanchard N, Jouve M, Bobard A, Moita C, Enninga J, Moita LF, Amigorena S, Savina A (2011) Sec22b regulates phagosomal maturation and antigen crosspresentation by dendritic cells. Cell 147: 1355–1368
-
(2011)
Cell
, vol.147
, pp. 1355-1368
-
-
Cebrian, I.1
Visentin, G.2
Blanchard, N.3
Jouve, M.4
Bobard, A.5
Moita, C.6
Enninga, J.7
Moita, L.F.8
Amigorena, S.9
Savina, A.10
-
7
-
-
84992645517
-
TRIMs and galectins globally cooperate and TRIM16 and galectin-3 co-direct autophagy in endomembrane damage homeostasis
-
Chauhan S, Kumar S, Jain A, Ponpuak M, Mudd MH, Kimura T, Choi SW, Peters R, Mandell M, Bruun JA, Johansen T, Deretic V (2016) TRIMs and galectins globally cooperate and TRIM16 and galectin-3 co-direct autophagy in endomembrane damage homeostasis. Dev Cell 39: 13–27
-
(2016)
Dev Cell
, vol.39
, pp. 13-27
-
-
Chauhan, S.1
Kumar, S.2
Jain, A.3
Ponpuak, M.4
Mudd, M.H.5
Kimura, T.6
Choi, S.W.7
Peters, R.8
Mandell, M.9
Bruun, J.A.10
Johansen, T.11
Deretic, V.12
-
8
-
-
77956605615
-
Serum ferritin is derived primarily from macrophages through a nonclassical secretory pathway
-
Cohen LA, Gutierrez L, Weiss A, Leichtmann-Bardoogo Y, Zhang DL, Crooks DR, Sougrat R, Morgenstern A, Galy B, Hentze MW, Lazaro FJ, Rouault TA, Meyron-Holtz EG (2010) Serum ferritin is derived primarily from macrophages through a nonclassical secretory pathway. Blood 116: 1574–1584
-
(2010)
Blood
, vol.116
, pp. 1574-1584
-
-
Cohen, L.A.1
Gutierrez, L.2
Weiss, A.3
Leichtmann-Bardoogo, Y.4
Zhang, D.L.5
Crooks, D.R.6
Sougrat, R.7
Morgenstern, A.8
Galy, B.9
Hentze, M.W.10
Lazaro, F.J.11
Rouault, T.A.12
Meyron-Holtz, E.G.13
-
9
-
-
84886797274
-
Autophagy in infection, inflammation, and immunity
-
Deretic V, Saitoh T, Akira S (2013) Autophagy in infection, inflammation, and immunity. Nat Rev Immunol 13: 722–737
-
(2013)
Nat Rev Immunol
, vol.13
, pp. 722-737
-
-
Deretic, V.1
Saitoh, T.2
Akira, S.3
-
10
-
-
84928550400
-
ATG14 promotes membrane tethering and fusion of autophagosomes to endolysosomes
-
Diao J, Liu R, Rong Y, Zhao M, Zhang J, Lai Y, Zhou Q, Wilz LM, Li J, Vivona S, Pfuetzner RA, Brunger AT, Zhong Q (2015) ATG14 promotes membrane tethering and fusion of autophagosomes to endolysosomes. Nature 520: 563–566
-
(2015)
Nature
, vol.520
, pp. 563-566
-
-
Diao, J.1
Liu, R.2
Rong, Y.3
Zhao, M.4
Zhang, J.5
Lai, Y.6
Zhou, Q.7
Wilz, L.M.8
Li, J.9
Vivona, S.10
Pfuetzner, R.A.11
Brunger, A.T.12
Zhong, Q.13
-
11
-
-
84904575441
-
WIPI2 links LC3 conjugation with PI3P, autophagosome formation, and pathogen clearance by recruiting Atg12-5-16L1
-
Dooley HC, Razi M, Polson HE, Girardin SE, Wilson MI, Tooze SA (2014) WIPI2 links LC3 conjugation with PI3P, autophagosome formation, and pathogen clearance by recruiting Atg12-5-16L1. Mol Cell 55: 238–252
-
(2014)
Mol Cell
, vol.55
, pp. 238-252
-
-
Dooley, H.C.1
Razi, M.2
Polson, H.E.3
Girardin, S.E.4
Wilson, M.I.5
Tooze, S.A.6
-
12
-
-
84908466248
-
Selective VPS34 inhibitor blocks autophagy and uncovers a role for NCOA4 in ferritin degradation and iron homeostasis in vivo
-
Dowdle WE, Nyfeler B, Nagel J, Elling RA, Liu S, Triantafellow E, Menon S, Wang Z, Honda A, Pardee G, Cantwell J, Luu C, Cornella-Taracido I, Harrington E, Fekkes P, Lei H, Fang Q, Digan ME, Burdick D, Powers AF et al (2014) Selective VPS34 inhibitor blocks autophagy and uncovers a role for NCOA4 in ferritin degradation and iron homeostasis in vivo. Nat Cell Biol 16: 1069–1079
-
(2014)
Nat Cell Biol
, vol.16
, pp. 1069-1079
-
-
Dowdle, W.E.1
Nyfeler, B.2
Nagel, J.3
Elling, R.A.4
Liu, S.5
Triantafellow, E.6
Menon, S.7
Wang, Z.8
Honda, A.9
Pardee, G.10
Cantwell, J.11
Luu, C.12
Cornella-Taracido, I.13
Harrington, E.14
Fekkes, P.15
Lei, H.16
Fang, Q.17
Digan, M.E.18
Burdick, D.19
Powers, A.F.20
more..
-
13
-
-
82455210868
-
Autophagy-based unconventional secretory pathway for extracellular delivery of IL-1beta
-
Dupont N, Jiang S, Pilli M, Ornatowski W, Bhattacharya D, Deretic V (2011) Autophagy-based unconventional secretory pathway for extracellular delivery of IL-1beta. EMBO J 30: 4701–4711
-
(2011)
EMBO J
, vol.30
, pp. 4701-4711
-
-
Dupont, N.1
Jiang, S.2
Pilli, M.3
Ornatowski, W.4
Bhattacharya, D.5
Deretic, V.6
-
14
-
-
77149155386
-
Unconventional secretion of Acb1 is mediated by autophagosomes
-
Duran JM, Anjard C, Stefan C, Loomis WF, Malhotra V (2010) Unconventional secretion of Acb1 is mediated by autophagosomes. J Cell Biol 188: 527–536
-
(2010)
J Cell Biol
, vol.188
, pp. 527-536
-
-
Duran, J.M.1
Anjard, C.2
Stefan, C.3
Loomis, W.F.4
Malhotra, V.5
-
15
-
-
79251587803
-
Phosphorylation of ULK1 (hATG1) by AMP-activated protein kinase connects energy sensing to mitophagy
-
Egan DF, Shackelford DB, Mihaylova MM, Gelino S, Kohnz RA, Mair W, Vasquez DS, Joshi A, Gwinn DM, Taylor R, Asara JM, Fitzpatrick J, Dillin A, Viollet B, Kundu M, Hansen M, Shaw RJ (2011) Phosphorylation of ULK1 (hATG1) by AMP-activated protein kinase connects energy sensing to mitophagy. Science 331: 456–461
-
(2011)
Science
, vol.331
, pp. 456-461
-
-
Egan, D.F.1
Shackelford, D.B.2
Mihaylova, M.M.3
Gelino, S.4
Kohnz, R.A.5
Mair, W.6
Vasquez, D.S.7
Joshi, A.8
Gwinn, D.M.9
Taylor, R.10
Asara, J.M.11
Fitzpatrick, J.12
Dillin, A.13
Viollet, B.14
Kundu, M.15
Hansen, M.16
Shaw, R.J.17
-
16
-
-
43949143804
-
The Atg16L complex specifies the site of LC3 lipidation for membrane biogenesis in autophagy
-
Fujita N, Itoh T, Omori H, Fukuda M, Noda T, Yoshimori T (2008) The Atg16L complex specifies the site of LC3 lipidation for membrane biogenesis in autophagy. Mol Biol Cell 19: 2092–2100
-
(2008)
Mol Biol Cell
, vol.19
, pp. 2092-2100
-
-
Fujita, N.1
Itoh, T.2
Omori, H.3
Fukuda, M.4
Noda, T.5
Yoshimori, T.6
-
17
-
-
84886897936
-
Recruitment of the autophagic machinery to endosomes during infection is mediated by ubiquitin
-
Fujita N, Morita E, Itoh T, Tanaka A, Nakaoka M, Osada Y, Umemoto T, Saitoh T, Nakatogawa H, Kobayashi S, Haraguchi T, Guan JL, Iwai K, Tokunaga F, Saito K, Ishibashi K, Akira S, Fukuda M, Noda T, Yoshimori T (2013) Recruitment of the autophagic machinery to endosomes during infection is mediated by ubiquitin. J Cell Biol 203: 115–128
-
(2013)
J Cell Biol
, vol.203
, pp. 115-128
-
-
Fujita, N.1
Morita, E.2
Itoh, T.3
Tanaka, A.4
Nakaoka, M.5
Osada, Y.6
Umemoto, T.7
Saitoh, T.8
Nakatogawa, H.9
Kobayashi, S.10
Haraguchi, T.11
Guan, J.L.12
Iwai, K.13
Tokunaga, F.14
Saito, K.15
Ishibashi, K.16
Akira, S.17
Fukuda, M.18
Noda, T.19
Yoshimori, T.20
more..
-
19
-
-
84873569898
-
Interaction between FIP200 and ATG16L1 distinguishes ULK1 complex-dependent and -independent autophagy
-
Gammoh N, Florey O, Overholtzer M, Jiang X (2013) Interaction between FIP200 and ATG16L1 distinguishes ULK1 complex-dependent and -independent autophagy. Nat Struct Mol Biol 20: 144–149
-
(2013)
Nat Struct Mol Biol
, vol.20
, pp. 144-149
-
-
Gammoh, N.1
Florey, O.2
Overholtzer, M.3
Jiang, X.4
-
20
-
-
84881506338
-
The ER-Golgi intermediate compartment is a key membrane source for the LC3 lipidation step of autophagosome biogenesis
-
Ge L, Melville D, Zhang M, Schekman R (2013) The ER-Golgi intermediate compartment is a key membrane source for the LC3 lipidation step of autophagosome biogenesis. eLife 2: e00947
-
(2013)
eLife
, vol.2
-
-
Ge, L.1
Melville, D.2
Zhang, M.3
Schekman, R.4
-
21
-
-
84927720203
-
Phosphatidylinositol 3-kinase and COPII generate LC3 lipidation vesicles from the ER-Golgi intermediate compartment
-
Ge L, Zhang M, Schekman R (2014) Phosphatidylinositol 3-kinase and COPII generate LC3 lipidation vesicles from the ER-Golgi intermediate compartment. eLife 3: e04135
-
(2014)
eLife
, vol.3
-
-
Ge, L.1
Zhang, M.2
Schekman, R.3
-
22
-
-
84925284243
-
O-GlcNAc-modification of SNAP-29 regulates autophagosome maturation
-
Guo B, Liang Q, Li L, Hu Z, Wu F, Zhang P, Ma Y, Zhao B, Kovacs AL, Zhang Z, Feng D, Chen S, Zhang H (2014) O-GlcNAc-modification of SNAP-29 regulates autophagosome maturation. Nat Cell Biol 16: 1215–1226
-
(2014)
Nat Cell Biol
, vol.16
, pp. 1215-1226
-
-
Guo, B.1
Liang, Q.2
Li, L.3
Hu, Z.4
Wu, F.5
Zhang, P.6
Ma, Y.7
Zhao, B.8
Kovacs, A.L.9
Zhang, Z.10
Feng, D.11
Chen, S.12
Zhang, H.13
-
23
-
-
84875365804
-
Autophagosomes form at ER-mitochondria contact sites
-
Hamasaki M, Furuta N, Matsuda A, Nezu A, Yamamoto A, Fujita N, Oomori H, Noda T, Haraguchi T, Hiraoka Y, Amano A, Yoshimori T (2013) Autophagosomes form at ER-mitochondria contact sites. Nature 495: 389–393
-
(2013)
Nature
, vol.495
, pp. 389-393
-
-
Hamasaki, M.1
Furuta, N.2
Matsuda, A.3
Nezu, A.4
Yamamoto, A.5
Fujita, N.6
Oomori, H.7
Noda, T.8
Haraguchi, T.9
Hiraoka, Y.10
Amano, A.11
Yoshimori, T.12
-
24
-
-
79953176280
-
Autophagy controls IL-1beta secretion by targeting pro-IL-1beta for degradation
-
Harris J, Hartman M, Roche C, Zeng SG, O'Shea A, Sharp FA, Lambe EM, Creagh EM, Golenbock DT, Tschopp J, Kornfeld H, Fitzgerald KA, Lavelle EC (2011) Autophagy controls IL-1beta secretion by targeting pro-IL-1beta for degradation. J Biol Chem 286: 9587–9597
-
(2011)
J Biol Chem
, vol.286
, pp. 9587-9597
-
-
Harris, J.1
Hartman, M.2
Roche, C.3
Zeng, S.G.4
O'Shea, A.5
Sharp, F.A.6
Lambe, E.M.7
Creagh, E.M.8
Golenbock, D.T.9
Tschopp, J.10
Kornfeld, H.11
Fitzgerald, K.A.12
Lavelle, E.C.13
-
25
-
-
47849097202
-
Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization
-
Hornung V, Bauernfeind F, Halle A, Samstad EO, Kono H, Rock KL, Fitzgerald KA, Latz E (2008) Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization. Nat Immunol 9: 847–856
-
(2008)
Nat Immunol
, vol.9
, pp. 847-856
-
-
Hornung, V.1
Bauernfeind, F.2
Halle, A.3
Samstad, E.O.4
Kono, H.5
Rock, K.L.6
Fitzgerald, K.A.7
Latz, E.8
-
26
-
-
84870880174
-
The hairpin-type tail-anchored SNARE syntaxin 17 targets to autophagosomes for fusion with endosomes/lysosomes
-
Itakura E, Kishi-Itakura C, Mizushima N (2012) The hairpin-type tail-anchored SNARE syntaxin 17 targets to autophagosomes for fusion with endosomes/lysosomes. Cell 151: 1256–1269
-
(2012)
Cell
, vol.151
, pp. 1256-1269
-
-
Itakura, E.1
Kishi-Itakura, C.2
Mizushima, N.3
-
27
-
-
84931287986
-
Bruton's tyrosine kinase is essential for NLRP3 inflammasome activation and contributes to ischaemic brain injury
-
Ito M, Shichita T, Okada M, Komine R, Noguchi Y, Yoshimura A, Morita R (2015) Bruton's tyrosine kinase is essential for NLRP3 inflammasome activation and contributes to ischaemic brain injury. Nat Commun 6: 7360
-
(2015)
Nat Commun
, vol.6
, pp. 7360
-
-
Ito, M.1
Shichita, T.2
Okada, M.3
Komine, R.4
Noguchi, Y.5
Yoshimura, A.6
Morita, R.7
-
29
-
-
84953373631
-
Activation of ULK Kinase and Autophagy by GABARAP Trafficking from the Centrosome Is Regulated by WAC and GM130
-
Joachim J, Jefferies HB, Razi M, Frith D, Snijders AP, Chakravarty P, Judith D, Tooze SA (2015) Activation of ULK Kinase and Autophagy by GABARAP Trafficking from the Centrosome Is Regulated by WAC and GM130. Mol Cell 60: 899–913
-
(2015)
Mol Cell
, vol.60
, pp. 899-913
-
-
Joachim, J.1
Jefferies, H.B.2
Razi, M.3
Frith, D.4
Snijders, A.P.5
Chakravarty, P.6
Judith, D.7
Tooze, S.A.8
-
30
-
-
0034329418
-
LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing
-
Kabeya Y, Mizushima N, Ueno T, Yamamoto A, Kirisako T, Noda T, Kominami E, Ohsumi Y, Yoshimori T (2000) LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing. EMBO J 19: 5720–5728
-
(2000)
EMBO J
, vol.19
, pp. 5720-5728
-
-
Kabeya, Y.1
Mizushima, N.2
Ueno, T.3
Yamamoto, A.4
Kirisako, T.5
Noda, T.6
Kominami, E.7
Ohsumi, Y.8
Yoshimori, T.9
-
31
-
-
84934449989
-
Regulation of endoplasmic reticulum turnover by selective autophagy
-
Khaminets A, Heinrich T, Mari M, Grumati P, Huebner AK, Akutsu M, Liebmann L, Stolz A, Nietzsche S, Koch N, Mauthe M, Katona I, Qualmann B, Weis J, Reggiori F, Kurth I, Hubner CA, Dikic I (2015) Regulation of endoplasmic reticulum turnover by selective autophagy. Nature 522: 354–358
-
(2015)
Nature
, vol.522
, pp. 354-358
-
-
Khaminets, A.1
Heinrich, T.2
Mari, M.3
Grumati, P.4
Huebner, A.K.5
Akutsu, M.6
Liebmann, L.7
Stolz, A.8
Nietzsche, S.9
Koch, N.10
Mauthe, M.11
Katona, I.12
Qualmann, B.13
Weis, J.14
Reggiori, F.15
Kurth, I.16
Hubner, C.A.17
Dikic, I.18
-
32
-
-
84955242756
-
Ubiquitin-dependent and independent signals in selective autophagy
-
Khaminets A, Behl C, Dikic I (2016) Ubiquitin-dependent and independent signals in selective autophagy. Trends Cell Biol 26: 6–16
-
(2016)
Trends Cell Biol
, vol.26
, pp. 6-16
-
-
Khaminets, A.1
Behl, C.2
Dikic, I.3
-
33
-
-
79551598347
-
AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1
-
Kim J, Kundu M, Viollet B, Guan KL (2011) AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1. Nat Cell Biol 13: 132–141
-
(2011)
Nat Cell Biol
, vol.13
, pp. 132-141
-
-
Kim, J.1
Kundu, M.2
Viollet, B.3
Guan, K.L.4
-
34
-
-
84872586081
-
Differential regulation of distinct Vps34 complexes by AMPK in nutrient stress and autophagy
-
Kim J, Kim YC, Fang C, Russell RC, Kim JH, Fan W, Liu R, Zhong Q, Guan KL (2013) Differential regulation of distinct Vps34 complexes by AMPK in nutrient stress and autophagy. Cell 152: 290–303
-
(2013)
Cell
, vol.152
, pp. 290-303
-
-
Kim, J.1
Kim, Y.C.2
Fang, C.3
Russell, R.C.4
Kim, J.H.5
Fan, W.6
Liu, R.7
Zhong, Q.8
Guan, K.L.9
-
35
-
-
84960432718
-
TRIM-mediated precision autophagy targets cytoplasmic regulators of innate immunity
-
Kimura T, Jain A, Choi SW, Mandell MA, Schroder K, Johansen T, Deretic V (2015) TRIM-mediated precision autophagy targets cytoplasmic regulators of innate immunity. J Cell Biol 210: 973–989
-
(2015)
J Cell Biol
, vol.210
, pp. 973-989
-
-
Kimura, T.1
Jain, A.2
Choi, S.W.3
Mandell, M.A.4
Schroder, K.5
Johansen, T.6
Deretic, V.7
-
36
-
-
85007550754
-
Precision Autophagy directed by Receptor-Regulators
-
Kimura T, Mandell M, Deretic V (2016) Precision Autophagy directed by Receptor-Regulators. J Cell Sci 125: 75–84
-
(2016)
J Cell Sci
, vol.125
, pp. 75-84
-
-
Kimura, T.1
Mandell, M.2
Deretic, V.3
-
37
-
-
60849099049
-
A role for NBR1 in autophagosomal degradation of ubiquitinated substrates
-
Kirkin V, Lamark T, Sou YS, Bjorkoy G, Nunn JL, Bruun JA, Shvets E, McEwan DG, Clausen TH, Wild P, Bilusic I, Theurillat JP, Overvatn A, Ishii T, Elazar Z, Komatsu M, Dikic I, Johansen T (2009) A role for NBR1 in autophagosomal degradation of ubiquitinated substrates. Mol Cell 33: 505–516
-
(2009)
Mol Cell
, vol.33
, pp. 505-516
-
-
Kirkin, V.1
Lamark, T.2
Sou, Y.S.3
Bjorkoy, G.4
Nunn, J.L.5
Bruun, J.A.6
Shvets, E.7
McEwan, D.G.8
Clausen, T.H.9
Wild, P.10
Bilusic, I.11
Theurillat, J.P.12
Overvatn, A.13
Ishii, T.14
Elazar, Z.15
Komatsu, M.16
Dikic, I.17
Johansen, T.18
-
38
-
-
84901751574
-
Ubiquitin is phosphorylated by PINK1 to activate parkin
-
Koyano F, Okatsu K, Kosako H, Tamura Y, Go E, Kimura M, Kimura Y, Tsuchiya H, Yoshihara H, Hirokawa T, Endo T, Fon EA, Trempe JF, Saeki Y, Tanaka K, Matsuda N (2014) Ubiquitin is phosphorylated by PINK1 to activate parkin. Nature 510: 162–166
-
(2014)
Nature
, vol.510
, pp. 162-166
-
-
Koyano, F.1
Okatsu, K.2
Kosako, H.3
Tamura, Y.4
Go, E.5
Kimura, M.6
Kimura, Y.7
Tsuchiya, H.8
Yoshihara, H.9
Hirokawa, T.10
Endo, T.11
Fon, E.A.12
Trempe, J.F.13
Saeki, Y.14
Tanaka, K.15
Matsuda, N.16
-
39
-
-
84957440559
-
TBC1D14 regulates autophagy via the TRAPP complex and ATG9 traffic
-
Lamb CA, Nuhlen S, Judith D, Frith D, Snijders AP, Behrends C, Tooze SA (2016) TBC1D14 regulates autophagy via the TRAPP complex and ATG9 traffic. EMBO J 35: 281–301
-
(2016)
EMBO J
, vol.35
, pp. 281-301
-
-
Lamb, C.A.1
Nuhlen, S.2
Judith, D.3
Frith, D.4
Snijders, A.P.5
Behrends, C.6
Tooze, S.A.7
-
40
-
-
84901310586
-
Mechanisms and functions of inflammasomes
-
Lamkanfi M, Dixit VM (2014) Mechanisms and functions of inflammasomes. Cell 157: 1013–1022
-
(2014)
Cell
, vol.157
, pp. 1013-1022
-
-
Lamkanfi, M.1
Dixit, V.M.2
-
41
-
-
84939804206
-
The ubiquitin kinase PINK1 recruits autophagy receptors to induce mitophagy
-
Lazarou M, Sliter DA, Kane LA, Sarraf SA, Wang C, Burman JL, Sideris DP, Fogel AI, Youle RJ (2015) The ubiquitin kinase PINK1 recruits autophagy receptors to induce mitophagy. Nature 524: 309–314
-
(2015)
Nature
, vol.524
, pp. 309-314
-
-
Lazarou, M.1
Sliter, D.A.2
Kane, L.A.3
Sarraf, S.A.4
Wang, C.5
Burman, J.L.6
Sideris, D.P.7
Fogel, A.I.8
Youle, R.J.9
-
42
-
-
0000906170
-
Induction of autophagy and inhibition of tumorigenesis by beclin 1
-
Liang XH, Jackson S, Seaman M, Brown K, Kempkes B, Hibshoosh H, Levine B (1999) Induction of autophagy and inhibition of tumorigenesis by beclin 1. Nature 402: 672–676
-
(1999)
Nature
, vol.402
, pp. 672-676
-
-
Liang, X.H.1
Jackson, S.2
Seaman, M.3
Brown, K.4
Kempkes, B.5
Hibshoosh, H.6
Levine, B.7
-
43
-
-
84862789618
-
Mitochondrial outer-membrane protein FUNDC1 mediates hypoxia-induced mitophagy in mammalian cells
-
Liu L, Feng D, Chen G, Chen M, Zheng Q, Song P, Ma Q, Zhu C, Wang R, Qi W, Huang L, Xue P, Li B, Wang X, Jin H, Wang J, Yang F, Liu P, Zhu Y, Sui S et al (2012) Mitochondrial outer-membrane protein FUNDC1 mediates hypoxia-induced mitophagy in mammalian cells. Nat Cell Biol 14: 177–185
-
(2012)
Nat Cell Biol
, vol.14
, pp. 177-185
-
-
Liu, L.1
Feng, D.2
Chen, G.3
Chen, M.4
Zheng, Q.5
Song, P.6
Ma, Q.7
Zhu, C.8
Wang, R.9
Qi, W.10
Huang, L.11
Xue, P.12
Li, B.13
Wang, X.14
Jin, H.15
Wang, J.16
Yang, F.17
Liu, P.18
Zhu, Y.19
Sui, S.20
more..
-
45
-
-
84883291965
-
Autophagy sequesters damaged lysosomes to control lysosomal biogenesis and kidney injury
-
Maejima I, Takahashi A, Omori H, Kimura T, Takabatake Y, Saitoh T, Yamamoto A, Hamasaki M, Noda T, Isaka Y, Yoshimori T (2013) Autophagy sequesters damaged lysosomes to control lysosomal biogenesis and kidney injury. EMBO J 32: 2336–2347
-
(2013)
EMBO J
, vol.32
, pp. 2336-2347
-
-
Maejima, I.1
Takahashi, A.2
Omori, H.3
Kimura, T.4
Takabatake, Y.5
Saitoh, T.6
Yamamoto, A.7
Hamasaki, M.8
Noda, T.9
Isaka, Y.10
Yoshimori, T.11
-
46
-
-
84899746695
-
Quantitative proteomics identifies NCOA4 as the cargo receptor mediating ferritinophagy
-
Mancias JD, Wang X, Gygi SP, Harper JW, Kimmelman AC (2014) Quantitative proteomics identifies NCOA4 as the cargo receptor mediating ferritinophagy. Nature 509: 105–109
-
(2014)
Nature
, vol.509
, pp. 105-109
-
-
Mancias, J.D.1
Wang, X.2
Gygi, S.P.3
Harper, J.W.4
Kimmelman, A.C.5
-
47
-
-
84907599058
-
TRIM proteins regulate autophagy and can target autophagic substrates by direct recognition
-
Mandell MA, Jain A, Arko-Mensah J, Chauhan S, Kimura T, Dinkins C, Silvestri G, Munch J, Kirchhoff F, Simonsen A, Wei Y, Levine B, Johansen T, Deretic V (2014) TRIM proteins regulate autophagy and can target autophagic substrates by direct recognition. Dev Cell 30: 394–409
-
(2014)
Dev Cell
, vol.30
, pp. 394-409
-
-
Mandell, M.A.1
Jain, A.2
Arko-Mensah, J.3
Chauhan, S.4
Kimura, T.5
Dinkins, C.6
Silvestri, G.7
Munch, J.8
Kirchhoff, F.9
Simonsen, A.10
Wei, Y.11
Levine, B.12
Johansen, T.13
Deretic, V.14
-
48
-
-
77149152566
-
Unconventional secretion of Pichia pastoris Acb1 is dependent on GRASP protein, peroxisomal functions, and autophagosome formation
-
Manjithaya R, Anjard C, Loomis WF, Subramani S (2010) Unconventional secretion of Pichia pastoris Acb1 is dependent on GRASP protein, peroxisomal functions, and autophagosome formation. J Cell Biol 188: 537–546
-
(2010)
J Cell Biol
, vol.188
, pp. 537-546
-
-
Manjithaya, R.1
Anjard, C.2
Loomis, W.F.3
Subramani, S.4
-
49
-
-
84861170022
-
Mycobacterium tuberculosis activates the DNA-dependent cytosolic surveillance pathway within macrophages
-
Manzanillo PS, Shiloh MU, Portnoy DA, Cox JS (2012) Mycobacterium tuberculosis activates the DNA-dependent cytosolic surveillance pathway within macrophages. Cell Host Microbe 11: 469–480
-
(2012)
Cell Host Microbe
, vol.11
, pp. 469-480
-
-
Manzanillo, P.S.1
Shiloh, M.U.2
Portnoy, D.A.3
Cox, J.S.4
-
50
-
-
32944468985
-
Gout-associated uric acid crystals activate the NALP3 inflammasome
-
Martinon F, Petrilli V, Mayor A, Tardivel A, Tschopp J (2006) Gout-associated uric acid crystals activate the NALP3 inflammasome. Nature 440: 237–241
-
(2006)
Nature
, vol.440
, pp. 237-241
-
-
Martinon, F.1
Petrilli, V.2
Mayor, A.3
Tardivel, A.4
Tschopp, J.5
-
51
-
-
84923820926
-
Lysosomal calcium signalling regulates autophagy through calcineurin and TFEB
-
Medina DL, Di Paola S, Peluso I, Armani A, De Stefani D, Venditti R, Montefusco S, Scotto-Rosato A, Prezioso C, Forrester A, Settembre C, Wang W, Gao Q, Xu H, Sandri M, Rizzuto R, De Matteis MA, Ballabio A (2015) Lysosomal calcium signalling regulates autophagy through calcineurin and TFEB. Nat Cell Biol 17: 288–299
-
(2015)
Nat Cell Biol
, vol.17
, pp. 288-299
-
-
Medina, D.L.1
Di Paola, S.2
Peluso, I.3
Armani, A.4
De Stefani, D.5
Venditti, R.6
Montefusco, S.7
Scotto-Rosato, A.8
Prezioso, C.9
Forrester, A.10
Settembre, C.11
Wang, W.12
Gao, Q.13
Xu, H.14
Sandri, M.15
Rizzuto, R.16
De Matteis, M.A.17
Ballabio, A.18
-
52
-
-
39849109338
-
Autophagy fights disease through cellular self-digestion
-
Mizushima N, Levine B, Cuervo AM, Klionsky DJ (2008) Autophagy fights disease through cellular self-digestion. Nature 451: 1069–1075
-
(2008)
Nature
, vol.451
, pp. 1069-1075
-
-
Mizushima, N.1
Levine, B.2
Cuervo, A.M.3
Klionsky, D.J.4
-
53
-
-
81055144784
-
Autophagy: renovation of cells and tissues
-
Mizushima N, Komatsu M (2011) Autophagy: renovation of cells and tissues. Cell 147: 728–741
-
(2011)
Cell
, vol.147
, pp. 728-741
-
-
Mizushima, N.1
Komatsu, M.2
-
55
-
-
84922366329
-
Multiple functions of the SNARE protein Snap29 in autophagy, endocytic, and exocytic trafficking during epithelial formation in Drosophila
-
Morelli E, Ginefra P, Mastrodonato V, Beznoussenko GV, Rusten TE, Bilder D, Stenmark H, Mironov AA, Vaccari T (2014) Multiple functions of the SNARE protein Snap29 in autophagy, endocytic, and exocytic trafficking during epithelial formation in Drosophila. Autophagy 10: 2251–2268
-
(2014)
Autophagy
, vol.10
, pp. 2251-2268
-
-
Morelli, E.1
Ginefra, P.2
Mastrodonato, V.3
Beznoussenko, G.V.4
Rusten, T.E.5
Bilder, D.6
Stenmark, H.7
Mironov, A.A.8
Vaccari, T.9
-
56
-
-
33749587661
-
The estrogen-responsive B box protein: a novel enhancer of interleukin-1beta secretion
-
Munding C, Keller M, Niklaus G, Papin S, Tschopp J, Werner S, Beer HD (2006) The estrogen-responsive B box protein: a novel enhancer of interleukin-1beta secretion. Cell Death Differ 13: 1938–1949
-
(2006)
Cell Death Differ
, vol.13
, pp. 1938-1949
-
-
Munding, C.1
Keller, M.2
Niklaus, G.3
Papin, S.4
Tschopp, J.5
Werner, S.6
Beer, H.D.7
-
57
-
-
84936132577
-
Bcl-2-like protein 13 is a mammalian Atg32 homologue that mediates mitophagy and mitochondrial fragmentation
-
Murakawa T, Yamaguchi O, Hashimoto A, Hikoso S, Takeda T, Oka T, Yasui H, Ueda H, Akazawa Y, Nakayama H, Taneike M, Misaka T, Omiya S, Shah AM, Yamamoto A, Nishida K, Ohsumi Y, Okamoto K, Sakata Y, Otsu K (2015) Bcl-2-like protein 13 is a mammalian Atg32 homologue that mediates mitophagy and mitochondrial fragmentation. Nat Commun 6: 7527
-
(2015)
Nat Commun
, vol.6
, pp. 7527
-
-
Murakawa, T.1
Yamaguchi, O.2
Hashimoto, A.3
Hikoso, S.4
Takeda, T.5
Oka, T.6
Yasui, H.7
Ueda, H.8
Akazawa, Y.9
Nakayama, H.10
Taneike, M.11
Misaka, T.12
Omiya, S.13
Shah, A.M.14
Yamamoto, A.15
Nishida, K.16
Ohsumi, Y.17
Okamoto, K.18
Sakata, Y.19
Otsu, K.20
more..
-
59
-
-
79960798816
-
SNARE proteins are required for macroautophagy
-
Nair U, Jotwani A, Geng J, Gammoh N, Richerson D, Yen WL, Griffith J, Nag S, Wang K, Moss T, Baba M, McNew JA, Jiang X, Reggiori F, Melia TJ, Klionsky DJ (2011) SNARE proteins are required for macroautophagy. Cell 146: 290–302
-
(2011)
Cell
, vol.146
, pp. 290-302
-
-
Nair, U.1
Jotwani, A.2
Geng, J.3
Gammoh, N.4
Richerson, D.5
Yen, W.L.6
Griffith, J.7
Nag, S.8
Wang, K.9
Moss, T.10
Baba, M.11
McNew, J.A.12
Jiang, X.13
Reggiori, F.14
Melia, T.J.15
Klionsky, D.J.16
-
60
-
-
79951642032
-
Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome
-
Nakahira K, Haspel JA, Rathinam VA, Lee SJ, Dolinay T, Lam HC, Englert JA, Rabinovitch M, Cernadas M, Kim HP, Fitzgerald KA, Ryter SW, Choi AM (2011) Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome. Nat Immunol 12: 222–230
-
(2011)
Nat Immunol
, vol.12
, pp. 222-230
-
-
Nakahira, K.1
Haspel, J.A.2
Rathinam, V.A.3
Lee, S.J.4
Dolinay, T.5
Lam, H.C.6
Englert, J.A.7
Rabinovitch, M.8
Cernadas, M.9
Kim, H.P.10
Fitzgerald, K.A.11
Ryter, S.W.12
Choi, A.M.13
-
62
-
-
84870527124
-
TBK1 kinase addiction in lung cancer cells is mediated via autophagy of Tax1 bp1/Ndp52 and non-canonical NF-kappaB signalling
-
Newman AC, Scholefield CL, Kemp AJ, Newman M, McIver EG, Kamal A, Wilkinson S (2012) TBK1 kinase addiction in lung cancer cells is mediated via autophagy of Tax1 bp1/Ndp52 and non-canonical NF-kappaB signalling. PLoS One 7: e50672
-
(2012)
PLoS One
, vol.7
-
-
Newman, A.C.1
Scholefield, C.L.2
Kemp, A.J.3
Newman, M.4
McIver, E.G.5
Kamal, A.6
Wilkinson, S.7
-
63
-
-
84874646724
-
FIP200 regulates targeting of Atg16L1 to the isolation membrane
-
Nishimura T, Kaizuka T, Cadwell K, Sahani MH, Saitoh T, Akira S, Virgin HW, Mizushima N (2013) FIP200 regulates targeting of Atg16L1 to the isolation membrane. EMBO Rep 14: 284–291
-
(2013)
EMBO Rep
, vol.14
, pp. 284-291
-
-
Nishimura, T.1
Kaizuka, T.2
Cadwell, K.3
Sahani, M.H.4
Saitoh, T.5
Akira, S.6
Virgin, H.W.7
Mizushima, N.8
-
64
-
-
82555187810
-
Image-based genome-wide siRNA screen identifies selective autophagy factors
-
Orvedahl A, Sumpter R Jr, Xiao G, Ng A, Zou Z, Tang Y, Narimatsu M, Gilpin C, Sun Q, Roth M, Forst CV, Wrana JL, Zhang YE, Luby-Phelps K, Xavier RJ, Xie Y, Levine B (2011) Image-based genome-wide siRNA screen identifies selective autophagy factors. Nature 480: 113–117
-
(2011)
Nature
, vol.480
, pp. 113-117
-
-
Orvedahl, A.1
Sumpter, R.2
Xiao, G.3
Ng, A.4
Zou, Z.5
Tang, Y.6
Narimatsu, M.7
Gilpin, C.8
Sun, Q.9
Roth, M.10
Forst, C.V.11
Wrana, J.L.12
Zhang, Y.E.13
Luby-Phelps, K.14
Xavier, R.J.15
Xie, Y.16
Levine, B.17
-
65
-
-
84899895138
-
The SNARE Sec22b has a non-fusogenic function in plasma membrane expansion
-
Petkovic M, Jemaiel A, Daste F, Specht CG, Izeddin I, Vorkel D, Verbavatz JM, Darzacq X, Triller A, Pfenninger KH, Tareste D, Jackson CL, Galli T (2014) The SNARE Sec22b has a non-fusogenic function in plasma membrane expansion. Nat Cell Biol 16: 434–444
-
(2014)
Nat Cell Biol
, vol.16
, pp. 434-444
-
-
Petkovic, M.1
Jemaiel, A.2
Daste, F.3
Specht, C.G.4
Izeddin, I.5
Vorkel, D.6
Verbavatz, J.M.7
Darzacq, X.8
Triller, A.9
Pfenninger, K.H.10
Tareste, D.11
Jackson, C.L.12
Galli, T.13
-
66
-
-
84938693671
-
Secretory autophagy
-
Ponpuak M, Mandell MA, Kimura T, Chauhan S, Cleyrat C, Deretic V (2015) Secretory autophagy. Curr Opin Cell Biol 35: 106–116
-
(2015)
Curr Opin Cell Biol
, vol.35
, pp. 106-116
-
-
Ponpuak, M.1
Mandell, M.A.2
Kimura, T.3
Chauhan, S.4
Cleyrat, C.5
Deretic, V.6
-
67
-
-
84884220705
-
Diverse autophagosome membrane sources coalesce in recycling endosomes
-
Puri C, Renna M, Bento CF, Moreau K, Rubinsztein DC (2013) Diverse autophagosome membrane sources coalesce in recycling endosomes. Cell 154: 1285–1299
-
(2013)
Cell
, vol.154
, pp. 1285-1299
-
-
Puri, C.1
Renna, M.2
Bento, C.F.3
Moreau, K.4
Rubinsztein, D.C.5
-
68
-
-
84898624312
-
Self and nonself: how autophagy targets mitochondria and bacteria
-
Randow F, Youle RJ (2014) Self and nonself: how autophagy targets mitochondria and bacteria. Cell Host Microbe 15: 403–411
-
(2014)
Cell Host Microbe
, vol.15
, pp. 403-411
-
-
Randow, F.1
Youle, R.J.2
-
69
-
-
79551546749
-
Autophagic substrate clearance requires activity of the syntaxin-5 SNARE complex
-
Renna M, Schaffner C, Winslow AR, Menzies FM, Peden AA, Floto RA, Rubinsztein DC (2011) Autophagic substrate clearance requires activity of the syntaxin-5 SNARE complex. J Cell Sci 124: 469–482
-
(2011)
J Cell Sci
, vol.124
, pp. 469-482
-
-
Renna, M.1
Schaffner, C.2
Winslow, A.R.3
Menzies, F.M.4
Peden, A.A.5
Floto, R.A.6
Rubinsztein, D.C.7
-
70
-
-
17744371839
-
The tripartite motif family identifies cell compartments
-
Reymond A, Meroni G, Fantozzi A, Merla G, Cairo S, Luzi L, Riganelli D, Zanaria E, Messali S, Cainarca S, Guffanti A, Minucci S, Pelicci PG, Ballabio A (2001) The tripartite motif family identifies cell compartments. EMBO J 20: 2140–2151
-
(2001)
EMBO J
, vol.20
, pp. 2140-2151
-
-
Reymond, A.1
Meroni, G.2
Fantozzi, A.3
Merla, G.4
Cairo, S.5
Luzi, L.6
Riganelli, D.7
Zanaria, E.8
Messali, S.9
Cainarca, S.10
Guffanti, A.11
Minucci, S.12
Pelicci, P.G.13
Ballabio, A.14
-
71
-
-
84862539692
-
The transcription factor TFEB links mTORC1 signaling to transcriptional control of lysosome homeostasis
-
Roczniak-Ferguson A, Petit CS, Froehlich F, Qian S, Ky J, Angarola B, Walther TC, Ferguson SM (2012) The transcription factor TFEB links mTORC1 signaling to transcriptional control of lysosome homeostasis. Sci Signal 5: ra42
-
(2012)
Sci Signal
, vol.5
, pp. ra42
-
-
Roczniak-Ferguson, A.1
Petit, C.S.2
Froehlich, F.3
Qian, S.4
Ky, J.5
Angarola, B.6
Walther, T.C.7
Ferguson, S.M.8
-
72
-
-
8544275815
-
Longins and their longin domains: regulated SNAREs and multifunctional SNARE regulators
-
Rossi V, Banfield DK, Vacca M, Dietrich LE, Ungermann C, D'Esposito M, Galli T, Filippini F (2004) Longins and their longin domains: regulated SNAREs and multifunctional SNARE regulators. Trends Biochem Sci 29: 682–688
-
(2004)
Trends Biochem Sci
, vol.29
, pp. 682-688
-
-
Rossi, V.1
Banfield, D.K.2
Vacca, M.3
Dietrich, L.E.4
Ungermann, C.5
D'Esposito, M.6
Galli, T.7
Filippini, F.8
-
73
-
-
84940457605
-
Therapeutic targeting of autophagy in neurodegenerative and infectious diseases
-
Rubinsztein DC, Bento CF, Deretic V (2015) Therapeutic targeting of autophagy in neurodegenerative and infectious diseases. J Exp Med 212: 979–990
-
(2015)
J Exp Med
, vol.212
, pp. 979-990
-
-
Rubinsztein, D.C.1
Bento, C.F.2
Deretic, V.3
-
74
-
-
84880331368
-
ULK1 induces autophagy by phosphorylating Beclin-1 and activating VPS34 lipid kinase
-
Russell RC, Tian Y, Yuan H, Park HW, Chang YY, Kim J, Kim H, Neufeld TP, Dillin A, Guan KL (2013) ULK1 induces autophagy by phosphorylating Beclin-1 and activating VPS34 lipid kinase. Nat Cell Biol 15: 741–750
-
(2013)
Nat Cell Biol
, vol.15
, pp. 741-750
-
-
Russell, R.C.1
Tian, Y.2
Yuan, H.3
Park, H.W.4
Chang, Y.Y.5
Kim, J.6
Kim, H.7
Neufeld, T.P.8
Dillin, A.9
Guan, K.L.10
-
75
-
-
47049100413
-
Essential role for Nix in autophagic maturation of erythroid cells
-
Sandoval H, Thiagarajan P, Dasgupta SK, Schumacher A, Prchal JT, Chen M, Wang J (2008) Essential role for Nix in autophagic maturation of erythroid cells. Nature 454: 232–235
-
(2008)
Nature
, vol.454
, pp. 232-235
-
-
Sandoval, H.1
Thiagarajan, P.2
Dasgupta, S.K.3
Schumacher, A.4
Prchal, J.T.5
Chen, M.6
Wang, J.7
-
76
-
-
79960322956
-
Caenorhabditis elegans SNAP-29 is required for organellar integrity of the endomembrane system and general exocytosis in intestinal epithelial cells
-
Sato M, Saegusa K, Sato K, Hara T, Harada A, Sato K (2011) Caenorhabditis elegans SNAP-29 is required for organellar integrity of the endomembrane system and general exocytosis in intestinal epithelial cells. Mol Biol Cell 22: 2579–2587
-
(2011)
Mol Biol Cell
, vol.22
, pp. 2579-2587
-
-
Sato, M.1
Saegusa, K.2
Sato, K.3
Hara, T.4
Harada, A.5
Sato, K.6
-
77
-
-
77950362382
-
The inflammasomes
-
Schroder K, Tschopp J (2010) The inflammasomes. Cell 140: 821–832
-
(2010)
Cell
, vol.140
, pp. 821-832
-
-
Schroder, K.1
Tschopp, J.2
-
78
-
-
84857997408
-
A lysosome-to-nucleus signalling mechanism senses and regulates the lysosome via mTOR and TFEB
-
Settembre C, Zoncu R, Medina DL, Vetrini F, Erdin S, Huynh T, Ferron M, Karsenty G, Vellard MC, Facchinetti V, Sabatini DM, Ballabio A (2012) A lysosome-to-nucleus signalling mechanism senses and regulates the lysosome via mTOR and TFEB. EMBO J 31: 1095–1108
-
(2012)
EMBO J
, vol.31
, pp. 1095-1108
-
-
Settembre, C.1
Zoncu, R.2
Medina, D.L.3
Vetrini, F.4
Erdin, S.5
Huynh, T.6
Ferron, M.7
Karsenty, G.8
Vellard, M.C.9
Facchinetti, V.10
Sabatini, D.M.11
Ballabio, A.12
-
79
-
-
84857195479
-
Activation of autophagy by inflammatory signals limits IL-1beta production by targeting ubiquitinated inflammasomes for destruction
-
Shi CS, Shenderov K, Huang NN, Kabat J, Abu-Asab M, Fitzgerald KA, Sher A, Kehrl JH (2012) Activation of autophagy by inflammatory signals limits IL-1beta production by targeting ubiquitinated inflammasomes for destruction. Nat Immunol 13: 255–263
-
(2012)
Nat Immunol
, vol.13
, pp. 255-263
-
-
Shi, C.S.1
Shenderov, K.2
Huang, N.N.3
Kabat, J.4
Abu-Asab, M.5
Fitzgerald, K.A.6
Sher, A.7
Kehrl, J.H.8
-
80
-
-
84939482242
-
Organelle-specific initiation of autophagy
-
Sica V, Galluzzi L, Bravo-San Pedro JM, Izzo V, Maiuri MC, Kroemer G (2015) Organelle-specific initiation of autophagy. Mol Cell 59: 522–539
-
(2015)
Mol Cell
, vol.59
, pp. 522-539
-
-
Sica, V.1
Galluzzi, L.2
Bravo-San Pedro, J.M.3
Izzo, V.4
Maiuri, M.C.5
Kroemer, G.6
-
81
-
-
22544448096
-
A mutation in SNAP29, coding for a SNARE protein involved in intracellular trafficking, causes a novel neurocutaneous syndrome characterized by cerebral dysgenesis, neuropathy, ichthyosis, and palmoplantar keratoderma
-
Sprecher E, Ishida-Yamamoto A, Mizrahi-Koren M, Rapaport D, Goldsher D, Indelman M, Topaz O, Chefetz I, Keren H, O'Brien TJ, Bercovich D, Shalev S, Geiger D, Bergman R, Horowitz M, Mandel H (2005) A mutation in SNAP29, coding for a SNARE protein involved in intracellular trafficking, causes a novel neurocutaneous syndrome characterized by cerebral dysgenesis, neuropathy, ichthyosis, and palmoplantar keratoderma. Am J Hum Genet 77: 242–251
-
(2005)
Am J Hum Genet
, vol.77
, pp. 242-251
-
-
Sprecher, E.1
Ishida-Yamamoto, A.2
Mizrahi-Koren, M.3
Rapaport, D.4
Goldsher, D.5
Indelman, M.6
Topaz, O.7
Chefetz, I.8
Keren, H.9
O'Brien, T.J.10
Bercovich, D.11
Shalev, S.12
Geiger, D.13
Bergman, R.14
Horowitz, M.15
Mandel, H.16
-
82
-
-
0032545419
-
Three novel proteins of the syntaxin/SNAP-25 family
-
Steegmaier M, Yang B, Yoo JS, Huang B, Shen M, Yu S, Luo Y, Scheller RH (1998) Three novel proteins of the syntaxin/SNAP-25 family. J Biol Chem 273: 34171–34179
-
(1998)
J Biol Chem
, vol.273
, pp. 34171-34179
-
-
Steegmaier, M.1
Yang, B.2
Yoo, J.S.3
Huang, B.4
Shen, M.5
Yu, S.6
Luo, Y.7
Scheller, R.H.8
-
83
-
-
0035923649
-
SNAP-29: a general SNARE protein that inhibits SNARE disassembly and is implicated in synaptic transmission
-
Su Q, Mochida S, Tian JH, Mehta R, Sheng ZH (2001) SNAP-29: a general SNARE protein that inhibits SNARE disassembly and is implicated in synaptic transmission. Proc Natl Acad Sci USA 98: 14038–14043
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 14038-14043
-
-
Su, Q.1
Mochida, S.2
Tian, J.H.3
Mehta, R.4
Sheng, Z.H.5
-
84
-
-
58049192897
-
Identification of Barkor as a mammalian autophagy-specific factor for Beclin 1 and class III phosphatidylinositol 3-kinase
-
Sun Q, Fan W, Chen K, Ding X, Chen S, Zhong Q (2008) Identification of Barkor as a mammalian autophagy-specific factor for Beclin 1 and class III phosphatidylinositol 3-kinase. Proc Natl Acad Sci USA 105: 19211–19216
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 19211-19216
-
-
Sun, Q.1
Fan, W.2
Chen, K.3
Ding, X.4
Chen, S.5
Zhong, Q.6
-
85
-
-
84878615771
-
Autophagosomal Syntaxin17-dependent lysosomal degradation maintains neuronal function in Drosophila
-
Takats S, Nagy P, Varga A, Pircs K, Karpati M, Varga K, Kovacs AL, Hegedus K, Juhasz G (2013) Autophagosomal Syntaxin17-dependent lysosomal degradation maintains neuronal function in Drosophila. J Cell Biol 201: 531–539
-
(2013)
J Cell Biol
, vol.201
, pp. 531-539
-
-
Takats, S.1
Nagy, P.2
Varga, A.3
Pircs, K.4
Karpati, M.5
Varga, K.6
Kovacs, A.L.7
Hegedus, K.8
Juhasz, G.9
-
86
-
-
84901308155
-
Interaction of the HOPS complex with syntaxin 17 mediates autophagosome clearance in Drosophila
-
Takats S, Pircs K, Nagy P, Varga A, Karpati M, Hegedus K, Kramer H, Kovacs AL, Sass M, Juhasz G (2014) Interaction of the HOPS complex with syntaxin 17 mediates autophagosome clearance in Drosophila. Mol Biol Cell 25: 1338–1354
-
(2014)
Mol Biol Cell
, vol.25
, pp. 1338-1354
-
-
Takats, S.1
Pircs, K.2
Nagy, P.3
Varga, A.4
Karpati, M.5
Hegedus, K.6
Kramer, H.7
Kovacs, A.L.8
Sass, M.9
Juhasz, G.10
-
87
-
-
0025044550
-
Mechanism of L-leucyl-L-leucine methyl ester-mediated killing of cytotoxic lymphocytes: dependence on a lysosomal thiol protease, dipeptidyl peptidase I, that is enriched in these cells
-
Thiele DL, Lipsky PE (1990) Mechanism of L-leucyl-L-leucine methyl ester-mediated killing of cytotoxic lymphocytes: dependence on a lysosomal thiol protease, dipeptidyl peptidase I, that is enriched in these cells. Proc Natl Acad Sci USA 87: 83–87
-
(1990)
Proc Natl Acad Sci USA
, vol.87
, pp. 83-87
-
-
Thiele, D.L.1
Lipsky, P.E.2
-
88
-
-
84857071710
-
Galectin 8 targets damaged vesicles for autophagy to defend cells against bacterial invasion
-
Thurston TL, Wandel MP, von Muhlinen N, Foeglein A, Randow F (2012) Galectin 8 targets damaged vesicles for autophagy to defend cells against bacterial invasion. Nature 482: 414–418
-
(2012)
Nature
, vol.482
, pp. 414-418
-
-
Thurston, T.L.1
Wandel, M.P.2
von Muhlinen, N.3
Foeglein, A.4
Randow, F.5
-
89
-
-
84992154479
-
The ATG conjugation systems are important for degradation of the inner autophagosomal membrane
-
Tsuboyama K, Koyama-Honda I, Sakamaki Y, Koike M, Morishita H, Mizushima N (2016) The ATG conjugation systems are important for degradation of the inner autophagosomal membrane. Science 354: 1036–1041
-
(2016)
Science
, vol.354
, pp. 1036-1041
-
-
Tsuboyama, K.1
Koyama-Honda, I.2
Sakamaki, Y.3
Koike, M.4
Morishita, H.5
Mizushima, N.6
-
90
-
-
84928905802
-
Sequential superresolution imaging of multiple targets using a single fluorophore
-
Valley CC, Liu S, Lidke DS, Lidke KA (2015) Sequential superresolution imaging of multiple targets using a single fluorophore. PLoS One 10: e0123941
-
(2015)
PLoS One
, vol.10
-
-
Valley, C.C.1
Liu, S.2
Lidke, D.S.3
Lidke, K.A.4
-
92
-
-
79960804104
-
Phosphorylation of the autophagy receptor optineurin restricts Salmonella growth
-
Wild P, Farhan H, McEwan DG, Wagner S, Rogov VV, Brady NR, Richter B, Korac J, Waidmann O, Choudhary C, Dotsch V, Bumann D, Dikic I (2011) Phosphorylation of the autophagy receptor optineurin restricts Salmonella growth. Science 333: 228–233
-
(2011)
Science
, vol.333
, pp. 228-233
-
-
Wild, P.1
Farhan, H.2
McEwan, D.G.3
Wagner, S.4
Rogov, V.V.5
Brady, N.R.6
Richter, B.7
Korac, J.8
Waidmann, O.9
Choudhary, C.10
Dotsch, V.11
Bumann, D.12
Dikic, I.13
-
93
-
-
0034671727
-
Subunit structure of a mammalian ER/Golgi SNARE complex
-
Xu D, Joglekar AP, Williams AL, Hay JC (2000) Subunit structure of a mammalian ER/Golgi SNARE complex. J Biol Chem 275: 39631–39639
-
(2000)
J Biol Chem
, vol.275
, pp. 39631-39639
-
-
Xu, D.1
Joglekar, A.P.2
Williams, A.L.3
Hay, J.C.4
-
94
-
-
84898713103
-
Drosophila SNAP-29 is an essential SNARE that binds multiple proteins involved in membrane traffic
-
Xu H, Mohtashami M, Stewart B, Boulianne G, Trimble WS (2014) Drosophila SNAP-29 is an essential SNARE that binds multiple proteins involved in membrane traffic. PLoS One 9: e91471
-
(2014)
PLoS One
, vol.9
-
-
Xu, H.1
Mohtashami, M.2
Stewart, B.3
Boulianne, G.4
Trimble, W.S.5
-
95
-
-
43649104579
-
Mitochondrial autophagy is an HIF-1-dependent adaptive metabolic response to hypoxia
-
Zhang H, Bosch-Marce M, Shimoda LA, Tan YS, Baek JH, Wesley JB, Gonzalez FJ, Semenza GL (2008) Mitochondrial autophagy is an HIF-1-dependent adaptive metabolic response to hypoxia. J Biol Chem 283: 10892–10903
-
(2008)
J Biol Chem
, vol.283
, pp. 10892-10903
-
-
Zhang, H.1
Bosch-Marce, M.2
Shimoda, L.A.3
Tan, Y.S.4
Baek, J.H.5
Wesley, J.B.6
Gonzalez, F.J.7
Semenza, G.L.8
-
96
-
-
84877342306
-
Cell biology. Unconventional secretion, unconventional solutions
-
Zhang M, Schekman R (2013) Cell biology. Unconventional secretion, unconventional solutions. Science 340: 559–561
-
(2013)
Science
, vol.340
, pp. 559-561
-
-
Zhang, M.1
Schekman, R.2
-
97
-
-
84955292894
-
Translocation of interleukin-1beta into a vesicle intermediate in autophagy-mediated secretion
-
Zhang M, Kenny S, Ge L, Xu K, Schekman R (2015) Translocation of interleukin-1beta into a vesicle intermediate in autophagy-mediated secretion. eLife 4: e11205
-
(2015)
eLife
, vol.4
-
-
Zhang, M.1
Kenny, S.2
Ge, L.3
Xu, K.4
Schekman, R.5
-
98
-
-
78651393239
-
A role for mitochondria in NLRP3 inflammasome activation
-
Zhou R, Yazdi AS, Menu P, Tschopp J (2011) A role for mitochondria in NLRP3 inflammasome activation. Nature 469: 221–225
-
(2011)
Nature
, vol.469
, pp. 221-225
-
-
Zhou, R.1
Yazdi, A.S.2
Menu, P.3
Tschopp, J.4
|