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Volumn 123, Issue 13, 2010, Pages 2238-2245

TRIM8 modulates STAT3 activity through negative regulation of PIAS3

Author keywords

IL 6; PIAS3; STAT3; TRIM8; Ubiquitin

Indexed keywords

INTERLEUKIN 6; PROTEASOME; PROTEIN DERIVATIVE; PROTEIN INHIBITOR OF ACTIVATED STAT; PROTEIN INHIBITOR OF ACTIVATED STAT3; STAT3 PROTEIN; TRIPARTITE MOTIF PROTEIN 8; UBIQUITIN; UNCLASSIFIED DRUG; CARRIER PROTEIN; CHAPERONE; NERVE PROTEIN; PIAS3 PROTEIN, HUMAN; PROTEIN TYROSINE KINASE; TRIM8 PROTEIN, HUMAN;

EID: 77954364837     PISSN: 00219533     EISSN: None     Source Type: Journal    
DOI: 10.1242/jcs.068981     Document Type: Article
Times cited : (74)

References (48)
  • 1
    • 0036595049 scopus 로고    scopus 로고
    • Suppressors of cytokine signalling (SOCS) in the immune system
    • Alexander, W. S. (2002). Suppressors of cytokine signalling (SOCS) in the immune system. Nat. Rev. Immunol. 2, 410-416. (Pubitemid 37328748)
    • (2002) Nature Reviews Immunology , vol.2 , Issue.6 , pp. 410-416
    • Alexander, W.S.1
  • 2
    • 0034708216 scopus 로고    scopus 로고
    • The U box is a modified RING finger-a common domain in ubiquitination
    • Aravind, L. and Koonin, E. V. (2000). The U box is a modified RING finger-a common domain in ubiquitination. Curr. Biol. 10, R132-R134.
    • (2000) Curr. Biol. , vol.10
    • Aravind, L.1    Koonin, E.V.2
  • 3
    • 34247378186 scopus 로고    scopus 로고
    • A leukemia fusion protein attenuates the spindle checkpoint and promotes aneuploidy
    • Boyapati, A., Yan, M., Peterson, L. F., Biggs, J. R., Le Beau, M. M. and Zhang, D. E. (2007). A leukemia fusion protein attenuates the spindle checkpoint and promotes aneuploidy. Blood 109, 3963-3971.
    • (2007) Blood , vol.109 , pp. 3963-3971
    • Boyapati, A.1    Yan, M.2    Peterson, L.F.3    Biggs, J.R.4    Le Beau, M.M.5    Zhang, D.E.6
  • 6
    • 0030725378 scopus 로고    scopus 로고
    • Specific inhibition of Stat3 signal transduction by PIAS3
    • Chung, C. D., Liao, J., Liu, B., Rao, X., Jay, P., Berta, P. and Shuai, K. (1997). Specific inhibition of Stat3 signal transduction by PIAS3. Science 278, 1803-1805.
    • (1997) Science , vol.278 , pp. 1803-1805
    • Chung, C.D.1    Liao, J.2    Liu, B.3    Rao, X.4    Jay, P.5    Berta, P.6    Shuai, K.7
  • 7
    • 0036629253 scopus 로고    scopus 로고
    • Protein quality control: U-box-containing E3 ubiquitin ligases join the fold
    • Cyr, D. M., Hohfeld, J. and Patterson, C. (2002). Protein quality control: U-box-containing E3 ubiquitin ligases join the fold. Trends Biochem. Sci. 27, 368-375.
    • (2002) Trends Biochem. Sci. , vol.27 , pp. 368-375
    • Cyr, D.M.1    Hohfeld, J.2    Patterson, C.3
  • 8
    • 0031821617 scopus 로고    scopus 로고
    • Studies of IFN-induced transcriptional activation uncover the Jak-Stat pathway
    • Darnell, J. E., Jr (1998). Studies of IFN-induced transcriptional activation uncover the Jak-Stat pathway. J. Interferon Cytokine Res. 18, 549-554.
    • (1998) J. Interferon Cytokine Res. , vol.18 , pp. 549-554
    • Darnell Jr., J.E.1
  • 9
    • 0142215648 scopus 로고    scopus 로고
    • The 'PINIT' motif, of a newly identified conserved domain of the PIAS protein family, is essential for nuclear retention of PIAS3L
    • Duval, D., Duval, G., Kedinger, C., Poch, O. and Boeuf, H. (2003). The 'PINIT' motif, of a newly identified conserved domain of the PIAS protein family, is essential for nuclear retention of PIAS3L. FEBS Lett. 554, 111-118.
    • (2003) FEBS Lett. , vol.554 , pp. 111-118
    • Duval, D.1    Duval, G.2    Kedinger, C.3    Poch, O.4    Boeuf, H.5
  • 10
    • 0033961923 scopus 로고    scopus 로고
    • RING for destruction?
    • Freemont, P. S. (2000). RING for destruction? Curr. Biol. 10, R84-R87.
    • (2000) Curr. Biol. , vol.10
    • Freemont, P.S.1
  • 14
    • 0026663539 scopus 로고
    • The ubiquitin system for protein degradation
    • Hershko, A. and Ciechanover, A. (1992). The ubiquitin system for protein degradation. Annu. Rev. Biochem. 61, 761-807.
    • (1992) Annu. Rev. Biochem. , vol.61 , pp. 761-807
    • Hershko, A.1    Ciechanover, A.2
  • 16
    • 0028913109 scopus 로고
    • A STAT protein domain that determines DNA sequence recognition suggests a novel DNA-binding domain
    • Horvath, C. M., Wen, Z. and Darnell, J. E., Jr (1995). A STAT protein domain that determines DNA sequence recognition suggests a novel DNA-binding domain. Genes Dev. 9, 984-994.
    • (1995) Genes Dev. , vol.9 , pp. 984-994
    • Horvath, C.M.1    Wen, Z.2    Darnell Jr., J.E.3
  • 17
    • 33947417336 scopus 로고    scopus 로고
    • Regulation of metastases by signal transducer and activator of transcription 3 signaling pathway: Clinical implications
    • Huang, S. (2007). Regulation of metastases by signal transducer and activator of transcription 3 signaling pathway: clinical implications. Clin. Cancer Res. 13, 1362-1366.
    • (2007) Clin. Cancer Res. , vol.13 , pp. 1362-1366
    • Huang, S.1
  • 18
    • 0028907874 scopus 로고
    • A family of proteins structurally and functionally related to the E6-AP ubiquitin-protein ligase
    • Huibregtse, J. M., Scheffner, M., Beaudenon, S. and Howley, P. M. (1995). A family of proteins structurally and functionally related to the E6-AP ubiquitin-protein ligase. Proc. Natl. Acad. Sci. USA 92, 2563-2567.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 2563-2567
    • Huibregtse, J.M.1    Scheffner, M.2    Beaudenon, S.3    Howley, P.M.4
  • 19
    • 2642520591 scopus 로고    scopus 로고
    • PIAS3 suppresses NFkappaB- mediated transcription by interacting with the p65/RelA subunit
    • Jang, H. D., Yoon, K., Shin, Y. J., Kim, J. and Lee, S. Y. (2004). PIAS3 suppresses NFkappaB- mediated transcription by interacting with the p65/RelA subunit. J. Biol. Chem. 279, 24873-24880.
    • (2004) J. Biol. Chem. , vol.279 , pp. 24873-24880
    • Jang, H.D.1    Yoon, K.2    Shin, Y.J.3    Kim, J.4    Lee, S.Y.5
  • 20
    • 0034266806 scopus 로고    scopus 로고
    • RING finger proteins: Mediators of ubiquitin ligase activity
    • Joazeiro, C. A. and Weissman, A. M. (2000). RING finger proteins: mediators of ubiquitin ligase activity. Cell 102, 549-552.
    • (2000) Cell , vol.102 , pp. 549-552
    • Joazeiro, C.A.1    Weissman, A.M.2
  • 22
    • 48649106832 scopus 로고    scopus 로고
    • Tripartite motif protein 32 facilitates cell growth and migration via degradation of Abl-interactor 2
    • Kano, S., Miyajima, N., Fukuda, S. and Hatakeyama, S. (2008). Tripartite motif protein 32 facilitates cell growth and migration via degradation of Abl-interactor 2. Cancer Res. 68, 5572-5580.
    • (2008) Cancer Res. , vol.68 , pp. 5572-5580
    • Kano, S.1    Miyajima, N.2    Fukuda, S.3    Hatakeyama, S.4
  • 23
    • 0023649672 scopus 로고
    • Activation and suppression of pp60c-src transforming ability by mutation of its primary sites of tyrosine phosphorylation
    • Kmiecik, T. E. and Shalloway, D. (1987). Activation and suppression of pp60c-src transforming ability by mutation of its primary sites of tyrosine phosphorylation. Cell 49, 65-73.
    • (1987) Cell , vol.49 , pp. 65-73
    • Kmiecik, T.E.1    Shalloway, D.2
  • 24
    • 0346121599 scopus 로고    scopus 로고
    • Suppressors of cytokine signaling and immunity
    • Kubo, M., Hanada, T. and Yoshimura, A. (2003). Suppressors of cytokine signaling and immunity. Nat. Immunol. 4, 1169-1176.
    • (2003) Nat. Immunol. , vol.4 , pp. 1169-1176
    • Kubo, M.1    Hanada, T.2    Yoshimura, A.3
  • 26
    • 0037127318 scopus 로고    scopus 로고
    • A new role for the STAT3 inhibitor, PIAS3: A repressor of microphthalmia transcription factor
    • Levy, C., Nechushtan, H. and Razin, E. (2002). A new role for the STAT3 inhibitor, PIAS3: a repressor of microphthalmia transcription factor. J. Biol. Chem. 277, 1962-1966.
    • (2002) J. Biol. Chem. , vol.277 , pp. 1962-1966
    • Levy, C.1    Nechushtan, H.2    Razin, E.3
  • 28
    • 30444452500 scopus 로고    scopus 로고
    • TRIM/RBCC, a novel class of 'single protein RING finger' E3 ubiquitin ligases
    • Meroni, G. and Diez-Roux, G. (2005). TRIM/RBCC, a novel class of 'single protein RING finger' E3 ubiquitin ligases. BioEssays 27, 1147-1157.
    • (2005) BioEssays , vol.27 , pp. 1147-1157
    • Meroni, G.1    Diez-Roux, G.2
  • 30
    • 27244444559 scopus 로고    scopus 로고
    • TRIM family proteins: Retroviral restriction and antiviral defence
    • Nisole, S., Stoye, J. P. and Saib, A. (2005). TRIM family proteins: retroviral restriction and antiviral defence. Nat. Rev. Microbiol. 3, 799-808.
    • (2005) Nat. Rev. Microbiol. , vol.3 , pp. 799-808
    • Nisole, S.1    Stoye, J.P.2    Saib, A.3
  • 31
    • 11144245872 scopus 로고    scopus 로고
    • Functional regulation of FEZ1 by the U-box-type ubiquitin ligase E4B contributes to neuritogenesis
    • Okumura, F., Hatakeyama, S., Matsumoto, M., Kamura, T. and Nakayama, K. I. (2004). Functional regulation of FEZ1 by the U-box-type ubiquitin ligase E4B contributes to neuritogenesis. J. Biol. Chem. 279, 53533-53543.
    • (2004) J. Biol. Chem. , vol.279 , pp. 53533-53543
    • Okumura, F.1    Hatakeyama, S.2    Matsumoto, M.3    Kamura, T.4    Nakayama, K.I.5
  • 32
    • 33847001685 scopus 로고    scopus 로고
    • ISG15 modification of the eIF4E cognate 4EHP enhances cap structure-binding activity of 4EHP
    • Okumura, F., Zou, W. and Zhang, D. E. (2007). ISG15 modification of the eIF4E cognate 4EHP enhances cap structure-binding activity of 4EHP. Genes Dev. 21, 255-260.
    • (2007) Genes Dev. , vol.21 , pp. 255-260
    • Okumura, F.1    Zou, W.2    Zhang, D.E.3
  • 33
    • 0031772952 scopus 로고    scopus 로고
    • SCF and APC: The Yin and Yang of cell cycle regulated proteolysis
    • Peters, J. M. (1998). SCF and APC: the Yin and Yang of cell cycle regulated proteolysis. Curr. Opin. Cell Biol. 10, 759-768.
    • (1998) Curr. Opin. Cell Biol. , vol.10 , pp. 759-768
    • Peters, J.M.1
  • 34
    • 34547941839 scopus 로고    scopus 로고
    • Acute myeloid leukemia with the 8q22;21q22 translocation: Secondary mutational events and alternative t(8;21) transcripts
    • Peterson, L. F., Boyapati, A., Ahn, E. Y., Biggs, J. R., Okumura, A. J., Lo, M. C., Yan, M. and Zhang, D. E. (2007). Acute myeloid leukemia with the 8q22;21q22 translocation: secondary mutational events and alternative t(8;21) transcripts. Blood 110, 799-805.
    • (2007) Blood , vol.110 , pp. 799-805
    • Peterson, L.F.1    Boyapati, A.2    Ahn, E.Y.3    Biggs, J.R.4    Okumura, A.J.5    Lo, M.C.6    Yan, M.7    Zhang, D.E.8
  • 35
    • 43649094723 scopus 로고    scopus 로고
    • Type I interferon-dependent and - Independent expression of tripartite motif proteins in immune cells
    • Rajsbaum, R., Stoye, J. P. and O'Garra, A. (2008). Type I interferon-dependent and - independent expression of tripartite motif proteins in immune cells. Eur. J. Immunol. 38, 619-630.
    • (2008) Eur. J. Immunol. , vol.38 , pp. 619-630
    • Rajsbaum, R.1    Stoye, J.P.2    O'Garra, A.3
  • 37
    • 0028898424 scopus 로고
    • Protein ubiquitination involving an E1-E2-E3 enzyme ubiquitin thioester cascade
    • Scheffner, M., Nuber, U. and Huibregtse, J. M. (1995). Protein ubiquitination involving an E1-E2-E3 enzyme ubiquitin thioester cascade. Nature 373, 81-83.
    • (1995) Nature , vol.373 , pp. 81-83
    • Scheffner, M.1    Nuber, U.2    Huibregtse, J.M.3
  • 38
    • 0032530972 scopus 로고    scopus 로고
    • Transformation of hematopoietic cell lines to growth-factor independence and induction of a fatal myelo- and lymphoproliferative disease in mice by retrovirally transduced TEL/JAK2 fusion genes
    • Schwaller, J., Frantsve, J., Aster, J., Williams, I. R., Tomasson, M. H., Ross, T. S., Peeters, P., Van Rompaey, L., Van Etten, R. A., Ilaria, R., Jr et al. (1998). Transformation of hematopoietic cell lines to growth-factor independence and induction of a fatal myelo- and lymphoproliferative disease in mice by retrovirally transduced TEL/JAK2 fusion genes. EMBO J. 17, 5321-5333.
    • (1998) EMBO J. , vol.17 , pp. 5321-5333
    • Schwaller, J.1    Frantsve, J.2    Aster, J.3    Williams, I.R.4    Tomasson, M.H.5    Ross, T.S.6    Peeters, P.7    Van Rompaey, L.8    Van Etten, R.A.9    Ilaria Jr., R.10
  • 39
    • 27644467440 scopus 로고    scopus 로고
    • Sumoylation of the estrogen receptor alpha hinge region regulates its transcriptional activity
    • Sentis, S., Le Romancer, M., Bianchin, C., Rostan, M. C. and Corbo, L. (2005). Sumoylation of the estrogen receptor alpha hinge region regulates its transcriptional activity. Mol. Endocrinol. 19, 2671-2684.
    • (2005) Mol. Endocrinol. , vol.19 , pp. 2671-2684
    • Sentis, S.1    Le Romancer, M.2    Bianchin, C.3    Rostan, M.C.4    Corbo, L.5
  • 40
    • 23444461182 scopus 로고    scopus 로고
    • Regulation of gene-activation pathways by pias proteins in the immune system
    • DOI 10.1038/nri1667
    • Shuai, K. and Liu, B. (2005). Regulation of gene-activation pathways by PIAS proteins in the immune system. Nat. Rev. Immunol. 5, 593-605. (Pubitemid 41113191)
    • (2005) Nature Reviews Immunology , vol.5 , Issue.8 , pp. 593-605
    • Shuai, K.1    Liu, B.2
  • 43
    • 0031953831 scopus 로고    scopus 로고
    • Stat3 activation by Src induces specific gene regulation and is required for cell transformation
    • Turkson, J., Bowman, T., Garcia, R., Caldenhoven, E., De Groot, R. P. and Jove, R. (1998). Stat3 activation by Src induces specific gene regulation and is required for cell transformation. Mol. Cell. Biol. 18, 2545-2552.
    • (1998) Mol. Cell. Biol. , vol.18 , pp. 2545-2552
    • Turkson, J.1    Bowman, T.2    Garcia, R.3    Caldenhoven, E.4    De Groot, R.P.5    Jove, R.6
  • 45
    • 0027441586 scopus 로고
    • Acute-phase response factor, a nuclear factor binding to acute-phase response elements, is rapidly activated by interleukin-6 at the posttranslational level
    • Wegenka, U. M., Buschmann, J., Lutticken, C., Heinrich, P. C. and Horn, F. (1993). Acute-phase response factor, a nuclear factor binding to acute-phase response elements, is rapidly activated by interleukin-6 at the posttranslational level. Mol. Cell. Biol. 13, 276-288.
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 276-288
    • Wegenka, U.M.1    Buschmann, J.2    Lutticken, C.3    Heinrich, P.C.4    Horn, F.5
  • 46
    • 61449150452 scopus 로고    scopus 로고
    • A specific epitope of protein inhibitor of activated STAT3 is responsible for the induction of apoptosis in rat transformed mast cells
    • Yagil, Z., Kay, G., Nechushtan, H. and Razin, E. (2009). A specific epitope of protein inhibitor of activated STAT3 is responsible for the induction of apoptosis in rat transformed mast cells. J. Immunol. 182, 2168-2175.
    • (2009) J. Immunol. , vol.182 , pp. 2168-2175
    • Yagil, Z.1    Kay, G.2    Nechushtan, H.3    Razin, E.4
  • 47
    • 0029069540 scopus 로고
    • Enhanced DNA-binding activity of a Stat3-related protein in cells transformed by the Src oncoprotein
    • Yu, C. L., Meyer, D. J., Campbell, G. S., Larner, A. C., Carter-Su, C., Schwartz, J. and Jove, R. (1995). Enhanced DNA-binding activity of a Stat3-related protein in cells transformed by the Src oncoprotein. Science 269, 81-83.
    • (1995) Science , vol.269 , pp. 81-83
    • Yu, C.L.1    Meyer, D.J.2    Campbell, G.S.3    Larner, A.C.4    Carter-Su, C.5    Schwartz, J.6    Jove, R.7
  • 48
    • 33845865825 scopus 로고    scopus 로고
    • Crosstalk between cancer and immune cells: Role of STAT3 in the tumour microenvironment
    • DOI 10.1038/nri1995, PII NRI1995
    • Yu, H., Kortylewski, M. and Pardoll, D. (2007). Crosstalk between cancer and immune cells: role of STAT3 in the tumour microenvironment. Nat. Rev. Immunol. 7, 41-51. (Pubitemid 46020826)
    • (2007) Nature Reviews Immunology , vol.7 , Issue.1 , pp. 41-51
    • Yu, H.1    Kortylewski, M.2    Pardoll, D.3


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