The tripartite motif family identifies cell compartments

EMBO Journal

Volumn 20, Issue 9, 2001, Pages 2140-2151

  Reymond, Alexandre ^a,b   Meroni, Germana ^a   Fantozzi, Anna ^c,d   Merla, Giuseppe ^a   Cairo, Stefano ^a   Luzi, Lucilla ^c,d   Riganelli, Daniela ^c   Zanaria, Elena ^a   Messali, Silvia ^a   Cainarca, Silvia ^a   Guffanti, Alessandro ^a   Minucci, Saverio ^d   Pelicci, Pier Giuseppe ^a,c,d   Ballabio, Andrea ^a,e  

^a TELETHON INSTITUTE OF GENETICS AND MEDICINE TIGEM   (Italy)

^b UNIVERSITY OF GENEVA MEDICAL SCHOOL   (Switzerland)

^c UNIVERSITY OF PERUGIA   (Italy)

^d EUROPEAN INSTITUTE OF ONCOLOGY   (Italy)

^e VITA SALUTE SAN RAFFAELE UNIVERSITY   (Italy)

Author keywords

Cell compartmentalization; Functional genomics; Nuclear bodies; RBCC; Tripartite motif

Indexed keywords

GENE PRODUCT; PROTEIN TRIM; TRIPARTITE MOTIF PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL COMPARTMENTALIZATION; CELL NUCLEUS INCLUSION BODY; CELL SPECIFICITY; GENOME; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN MOTIF; PROTEIN POLYMERIZATION;

AMINO ACID MOTIFS; ANIMALS; BLOTTING, NORTHERN; CARRIER PROTEINS; CELL COMPARTMENTATION; CELL LINE; CHROMOSOME MAPPING; CLONING, MOLECULAR; DATABASES, FACTUAL; EMBRYO; HUMANS; IN SITU HYBRIDIZATION; MICE; MOLECULAR SEQUENCE DATA; MULTIGENE FAMILY; MUTAGENESIS, SITE-DIRECTED; NERVE TISSUE PROTEINS; ORGAN SPECIFICITY; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID; SUBCELLULAR FRACTIONS; TWO-HYBRID SYSTEM TECHNIQUES;

ANIMALIA;

EID: 17744371839     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/20.9.2140     Document Type: Article

References (63)

1. The genome sequence of Drosophila melanogaster
2. Gene encoding a new RING-B-box-coiled-coil protein is mutated in mulibrey nanism
3. A zinc-binding domain is required for targeting the maternal nuclear protein PwA33 to lampbrush chromosome loops
4. The complete genome sequence of Escherichia coli K-12
5. RING fingers and B-boxes: Zinc-binding protein-protein interaction domains
6. Genomic biology
7. MID2, a homologue of the Opitz syndrome gene MID1: Similarities in subcellular localization and differences in expression during development
8. Functional characterization of the Opitz syndrome gene product (midin): Evidence for homodimerization and association with microtubules throughout the cell cycle
9. Involvement of the rfp tripartite motif in protein-protein interactions and subcellular distribution
10. Ret finger protein is a normal component of PML nuclear bodies and interacts directly with PML
11. The DNA sequence of human chromosome 22
12. A novel macromolecular structure is a target of the promyelocyte-retinoic acid receptor oncoprotein
13. Interaction mating reveals binary and ternary connections between Drosophila cell cycle regulators
14. ncl-1 is required for the regulation of cell size and ribosomal RNA synthesis in Caenorhabditis elegans
15. KAP-1, a novel corepressor for the highly conserved KRAB repression domain
16. Life with 6000 genes
17. Acute promyelocytic leukemia: From genetics to treatment
18. Effects on differentiation by the promyelocytic leukemia PML/RARα protein depend on the fusion of the PML protein dimerization and RARα DNA binding domains
19. Formation of PML/RARα high molecular weight nuclear complexes through the PML coiled-coil region is essential for the PML/RARα-mediated retinoic acid response
20. 1 and S phase protein phosphatase that associates with Cdk2
21. A RING finger motif regulates transforming activity of the rfp/ret fusion gene
22. B30.2-like domain proteins: Update and new insights into a rapidly expanding family of proteins
23. PML is critical for ND10 formation and recruits the PML-interacting protein daxx to this nuclear structure when modified by SUMO-1
24. Structure and function of a human TAFII250 double bromodomain module
25. A novel member of the RING finger family, KRIP-1, associates with the KRAB-A transcriptional repressor domain of zinc finger proteins
26. The Eps8 protein coordinates EGF receptor signalling through Rac and trafficking through Rab5
27. The N-terminal part of TIF1, a putative mediator of the ligand-dependent activation function (AF-2) of nuclear receptors, is fused to B-raf in the oncogenic protein T18
28. A possible involvement of TIF1α and TIF1β in the epigenetic control of transcription by nuclear receptors
29. The association of Xenopus nuclear factor 7 with subcellular structures is dependent upon phosphorylation and specific domains
30. Coiled coils: New structures and new functions
31. A biochemical genomics approach for identifying genes by the activity of their products
32. Mlx, a new Max-like bHLHZip family member: The center stage of a novel transcription factors regulatory pathway?
33. Oligomerization of RAR and AML1 transcription factors as a novel mechanism of oncogenic activation
34. Transcriptional repression by RING finger protein TIF1β that interacts with the KRAB repressor domain of KOX1
35. Interaction with members of the heterochromatin protein 1 (HP1) family and histone deacetylation are differentially involved in transcriptional silencing by members of the TIF1 family
36. PML regulates p53 acetylation and premature senescence induced by oncogenic Ras
37. Reconstitution of the KRAB-KAP-1 repressor complex: A model system for defining the molecular anatomy of RING-B box-coiled-coil domain-mediated protein-protein interactions
38. PMLRAR homodimers: Distinct DNA binding properties and heteromeric interactions with RXR
39. Opitz G/BBB syndrome, a defect of midline development, is due to mutations in a new RING finger gene on Xp22
40. PML induces a novel caspase-independent death process
41. A novel zinc finger coiled-coil domain in a family of nuclear proteins
42. p16 proteins from melanoma-prone families are deficient in binding to Cdk4
43. Large-scale analysis of the yeast genome by transposon tagging and gene disruption
44. Expression pattern of the Kallmann syndrome gene in the olfactory system suggests a role in neuronal targeting
45. The Opitz syndrome gene product, MID1, associates with microtubules
46. Linking genome and proteome by mass spectrometry: Large-scale identification of yeast proteins from two dimensional gels
47. Finely tuned regulation of cytoplasmic retention of Xenopus nuclear factor 7 by phosphorylation of individual threonine residues
48. A novel repeat domain that is often associated with RING finger and B-box motifs
49. The lin-41 RBCC gene acts in the C. elegans heterochronic pathway between the let-7 regulatory RNA and the LIN-29 transcription factor
50. Developmentally regulated expression of a human 'finger'-containing gene encoded by the 5′ half of the ret transforming gene
51. Genome sequence of the nematode C. elegans: A platform for investigating biology
52. The DNA sequence of human chromosome 21
53. A candidate gene for familial Mediterranean fever
54. Ancient missense mutations in a new member of the RoRet gene family are likely to cause familial Mediterranean fever
55. A comprehensive analysis of protein-protein interactions in Saccharomyces cerevisiae
56. TIF1γ, a novel member of the transcriptional intermediary factor 1 family
57. ARD1, a 64-kDa bifunctional protein containing an 18-kDa GTP-binding ADP-ribosylation factor domain and a 46-kDa GTPase-activating domain
58. Protein interaction mapping in C. elegans using proteins involved in vulval development
59. PML is essential for multiple apoptotic pathways
60. A RA-dependent, tumour-growth suppressive transcription complex is the target of the PML-RARα and T18 oncoproteins
61. A role for PML and the nuclear body in genomic stability
62. Role of SUMO-1-modified PML in nuclear body formation
63. The transcriptional role of PML and the nuclear body