Erratum: TRIM68 Negatively Regulates IFN-β Production by Degrading TRK Fused Gene, a Novel Driver of IFN-β Downstream of Anti-Viral Detection Systems. (PLoS ONE (2014) 9:7 (e101503) DOI: 10.1371/journal.pone.0101503);TRIM68 negatively regulates IFN-β production by degrading TRK fused gene, a novel driver of IFN-β downstream of anti-viral detection systems

PLoS ONE

Volumn 9, Issue 7, 2014, Pages

  Wynne, Claire ^a,b   Lazzari, Elisa ^a   Smith, Siobhán ^a   McCarthy, Eoghan M ^a   Gabhann, Joan Ní ^a   Kallal, Lara E ^c   Higgs, Rowan ^a   Cryan, Sally Ann ^a,d   Biron, Christine A ^c   Jefferies, Caroline A ^a  

^a ROYAL COLLEGE OF SURGEONS IN IRELAND   (Ireland)

^b DUBLIN INSTITUTE OF TECHNOLOGY   (Ireland)

^c BROWN UNIVERSITY   (United States)

^d TRINITY COLLEGE DUBLIN   (Ireland)

Author keywords

[No Author keywords available]

Indexed keywords

BETA INTERFERON; I KAPPA B KINASE GAMMA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERFERON; POLYINOSINIC POLYCYTIDYLIC ACID; PROTEIN TANK; RIG I LIKE RECEPTOR; TOLL LIKE RECEPTOR; TRIM68 PROTEIN; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR; UNCLASSIFIED DRUG; AUTOANTIGEN; DDX58 PROTEIN, HUMAN; DEAD BOX PROTEIN; PROTEIN; TFG PROTEIN, HUMAN; TRIM68 PROTEIN, HUMAN; UBIQUITIN PROTEIN LIGASE;

ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DEGRADATION; DOWN REGULATION; EMBRYO; GENE; GENE FUNCTION; GENE IDENTIFICATION; GENE INTERACTION; GENE OVEREXPRESSION; GENE TARGETING; GENETIC ASSOCIATION; HUMAN; HUMAN CELL; LYSOSOMAL DEGRADATION; MONOCYTE; PROMOTER REGION; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEOMICS; TFG GENE; TGF GENE; TLR3 GENE; TRANSCRIPTION REGULATION; UBIQUITINATION; VIRUS DETECTION; BIOSYNTHESIS; CHEMISTRY; DEFICIENCY; GENETICS; HEK293 CELL LINE; HELA CELL LINE; IMMUNOLOGY; INNATE IMMUNITY; METABOLISM; PROTEIN DEGRADATION; PROTEIN TERTIARY STRUCTURE; VIRUS;

AUTOANTIGENS; DEAD-BOX RNA HELICASES; HEK293 CELLS; HELA CELLS; HUMANS; IMMUNITY, INNATE; INTERFERON-BETA; PROMOTER REGIONS, GENETIC; PROTEIN STRUCTURE, TERTIARY; PROTEINS; PROTEOLYSIS; UBIQUITIN-PROTEIN LIGASES; UBIQUITINATION; VIRUSES;

EID: 84904364644     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0117957     Document Type: Erratum

References (57)

1. Versteeg Gijs A, Rajsbaum R, Sánchez-Aparicio Maria T, Maestre Ana M, Valdiviezo J, et al. (2013) The E3-Ligase TRIM Family of Proteins Regulates Signaling Pathways Triggered by Innate Immune Pattern-Recognition Receptors. Immunity 38: 384-398.
2. Yang B, Wang J, Wang Y, Zhou H, Wu X, et al. (2013) Novel Function of Trim44 Promotes an Antiviral Response by Stabilizing VISA. The Journal of Immunology 190: 3613-3619.
3. Xue Q, Zhou Z, Lei X, Liu X, He B, et al. (2012) TRIM38 Negatively Regulates TLR3-Mediated IFN-β Signaling by Targeting TRIF for Degradation. PLoS ONE 7: e46825.
4. Li Q, Yan J, Mao A-P, Li C, Ran Y, et al. (2011) Tripartite motif 8 (TRIM8) modulates TNFα- and IL-1β-triggered NF-κB activation by targeting TAK1 for K63-linked polyubiquitination. Proceedings of the National Academy of Sciences 108: 19341-19346.
5. Noguchi K, Okumura F, Takahashi N, Kataoka A, Kamiyama T, et al. (2011) TRIM40 promotes neddylation of IKKγ and is downregulated in gastrointestinal cancers. Carcinogenesis 32: 995-1004.
6. Yu S, Gao B, Duan Z, Xu W, Xiong S (2011) Identification of tripartite motif-containing 22 (TRIM22) as a novel NF-κB activator. Biochemical and Biophysical Research Communications 410: 247-251.
7. Higgs R, Ní Gabhann J, Larbi NB, Breen EP, Fitzgerald KA, et al. (2008) The E3 Ubiquitin Ligase Ro52 Negatively Regulates IFN-β Production Post-Pathogen Recognition by Polyubiquitin-Mediated Degradation of IRF3. The Journal of Immunology 181: 1780-1786.
8. Higgs R, Lazzari E, Wynne C, Ní Gabhann J, Espinosa A, et al. (2010) Self Protection from Anti-Viral Responses - Ro52 Promotes Degradation of the Transcription Factor IRF7 Downstream of the Viral Toll-Like Receptors. PLoS ONE 5: e11776.
9. Kondo T, Watanabe M, Hatakeyama S (2012) TRIM59 interacts with ECSIT and negatively regulates NF-κB and IRF-3/7-mediated signal pathways. Biochemical and Biophysical Research Communications 422: 501-507.
10. Shibata M, Sato T, Nukiwa R, Ariga T, Hatakeyama S (2012) TRIM45 negatively regulates NF-κB-mediated transcription and suppresses cell proliferation. Biochemical and Biophysical Research Communications 423: 104-109.
11. Zhao W, Wang L, Zhang M, Wang P, Yuan C, et al. (2012) Tripartite Motif-Containing Protein 38 Negatively Regulates TLR3/4- and RIG-I-Mediated IFN-β Production and Antiviral Response by Targeting NAP1. The Journal of Immunology 188: 5311-5318.
12. Zhao W, Wang L, Zhang M, Yuan C, Gao C (2012) E3 Ubiquitin Ligase Tripartite Motif 38 Negatively Regulates TLR-Mediated Immune Responses by Proteasomal Degradation of TNF Receptor-Associated Factor 6 in Macrophages. The Journal of Immunology 188: 2567-2574.
13. Qiu H, Huang F, Xiao H, Sun B, Yang R (2013) TRIM22 inhibits the TRAF6-stimulated NF-κB pathway by targeting TAB2 for degradation. Virologica Sinica: 1-7.
14. Goubau D, Deddouche S, Reise Sousa C (2013) Cytosolic Sensing of Viruses. Immunity 38: 855-869.
15. Paludan SR, Bowie AG (2013) Immune Sensing of DNA. Immunity 38: 870-880.
16. Kawai T, Akira S (2008) Toll-like Receptor and RIG-1-like Receptor Signaling. Annals of the New York Academy of Sciences 1143: 1-20.
17. Ozato K, Shin D-M, Chang T-H, Morse HC (2008) TRIM family proteins and their emerging roles in innate immunity. Nat Rev Immunol 8: 849-860.
18. Reymond A, Meroni G, Fantozzi A, Merla G, Cairo S, et al. (2001) The tripartite motif family identifies cell compartments. EMBO J 20: 2140-2151. (Pubitemid 32410584)
19. Perez-Caballero D, Hatziioannou T, Yang A, Cowan S, Bieniasz PD (2005) Human Tripartite Motif 5a Domains Responsible for Retrovirus Restriction Activity and Specificity. Journal of Virology 79: 8969-8978. (Pubitemid 40934808)
20. Clark G, Reichlin M, Tomasi TB Jr (1969) Characterization of a soluble cytoplasmic antigen reactive sera from patients with systemic lupus erythematosus. J Immunol 102: 117-122.
21. Mattioli M, Reichlin M (1974) Heterogeneity of RNA protein antigens reactive with sera of patients with systemic lupus erythematosus. Description of a cytoplasmic nonribosomal antigen. Arthritis Rheum 17: 421-429.
22. Alspaugh MA, Tan EM (1975) Antibodies to cellular antigens in Sjögren's syndrome. J Clin Invest 55: 1067-1073.
23. Espinosa A, Dardalhon V, Brauner S, Ambrosi A, Higgs R, et al. (2009) Loss of the lupus autoantigen Ro52/Trim21 induces tissue inflammation and systemic autoimmunity by disregulating the IL-23-Th17 pathway. The Journal of Experimental Medicine 206: 1661-1671.
24. Kong HJ, Anderson DE, Lee CH, Jang MK, Tamura T, et al. (2007) Cutting Edge: Autoantigen Ro52 Is an Interferon Inducible E3 Ligase That Ubiquitinates IRF-8 and Enhances Cytokine Expression in Macrophages. The Journal of Immunology 179: 26-30. (Pubitemid 46986512)
25. Yang K, Shi H-X, Liu X-Y, Shan Y-F, Wei B, et al. (2009) TRIM21 Is Essential to Sustain IFN Regulatory Factor 3 Activation during Antiviral Response. The Journal of Immunology 182: 3782-3792.
26. McEwan WA, Tam JCH, Watkinson RE, Bidgood SR, Mallery DL, et al. (2013) Intracellular antibody-bound pathogens stimulate immune signaling via the Fc receptor TRIM21. Nat Immunol 14: 327-336.
27. Jefferies C, Wynne C, Higgs R (2011) Antiviral TRIMs: friend or foe in autoimmune and autoinflammatory disease? Nat Rev Immunol 11: 617-625.
28. Miyajima N, Maruyama S, Bohgaki M, Kano S, Shigemura M, et al. (2008) TRIM68 Regulates Ligand-Dependent Transcription of Androgen Receptor in Prostate Cancer Cells. Cancer Research 68: 3486-3494.
29. Li Y, Kong D, Ahmad A, Bao B, Dyson G, et al. (2012) Epigenetic deregulation of miR-29a and miR-1256 by isoflavone contributes to the inhibition of prostate cancer cell growth and invasion. Epigenetics 7: 940-949.
30. Baek Sorensen R, Faurschou M, Troelsen L, Schrama D, Jacobsen S, et al. (2009) Melanoma Inhibitor of Apoptosis Protein (ML-IAP) Specific Cytotoxic T Lymphocytes Cross-React with an Epitope from the Auto-Antigen SS56. J Invest Dermatol 129: 1992-1999.
31. Billaut-Mulot OC, Kolesnitchenko C, Truong V, Chan MJ, Hachula EK (2001) SS-56, a novel cellular target of autoantibody responses in Sjögren syndrome and systemic lupus erythematosus. J Clin Invest 108: 861-869.
32. Miranda C, Roccato E, Raho G, Pagliardini S, Pierotti MA, et al. (2006) The TFG protein, involved in oncogenic rearrangements, interacts with TANK and NEMO, two proteins involved in the NF-κB pathway. Journal of Cellular Physiology 208: 154-160. (Pubitemid 43849000)
33. Livak KJ, Schmittgen TD (2001) Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2-ΔΔCT Method. Methods 25: 402-408. (Pubitemid 34164012)
34. Clark G, Reichlin M, Tomasi TB (1969) Characterization of a Soluble Cytoplasmic Antigen Reactive with Sera from Patients with Systemic Lupus Erythmatosus. The Journal Of Immunology 102: 117-122.
35. Billaut-Mulot O, Cocude Cc, Kolesnitchenko V, Truong M-J, Chan EKL, et al. (2001) SS-56, a novel cellular target of autoantibody responses in Sjögren syndrome and systemic lupus erythematosus. The Journal of Clinical Investigation 108: 861-869.
36. D'Cruz AA, Babon JJ, Norton RS, Nicola NA, Nicholson SE (2013) Structure and function of the SPRY/B30.2 domain proteins involved in innate immunity. Protein Science 22: 1-10.
37. Garlanda C, Riva F, Polentarutti N, Buracchi C, Sironi M, et al. (2004) Intestinal inflammation in mice deficient in Tir8, an inhibitory member of the IL-1 receptor family. Proceedings of the National Academy of Sciences of the United States of America 101: 3522-3526. (Pubitemid 38338228)
38. Xiao H, Yin W, Khan MA, Gulen MF, Zhou H, et al. (2010) Loss of Single Immunoglobulin Interlukin-1 Receptor-Related Molecule Leads to Enhanced Colonic Polyposis in Apcmin Mice. Gastroenterology 139: 574-585.
39. Hatakeyama S (2011) TRIM proteins and cancer. Nat Rev Cancer 11: 792-804.
40. Nisole S, Stoye J, Saib A (2005) TRIM family proteins: retroviral restriction and antiviral defence. Nat Rev Microbiol 3: 799-808. (Pubitemid 41518740)
41. Kawai T, Akira S (2011) Regulation of innate immune signalling pathways by the tripartite motif (TRIM) family proteins. EMBO Molecular Medicine 3: 513-527.
42. McNab FW, Rajsbaum R, Stoye JP, O'Garra A (2011) Tripartite-motif proteins and innate immune regulation. Current Opinion in Immunology 23: 46-56.
43. Rajsbaum R, Stoye JP, O'Garra A (2008) Type I interferon-dependent and - independent expression of tripartite motif proteins in immune cells. European Journal of Immunology 38: 619-630.
44. Stremlau M, Owens CM, Perron MJ, Kiessling M, Autissier P, et al. (2004) The cytoplasmic body component TRIM5[alpha] restricts HIV-1 infection in Old World monkeys. Nature 427: 848-853. (Pubitemid 38297747)
45. Lee N-R, Shin H-B, Kim H-I, Choi M-S, Inn K-S (2013) Negative regulation of RIG-I-mediated antiviral signaling by TRK-fused gene (TFG) protein. Biochemical and Biophysical Research Communications 437: 168-172.
46. Endoh K, Nishi M, Ishiguro H, Uemura H, Miyagi Y, et al. (2012) Identification of phosphorylated proteins involved in the oncogenesis of prostate cancer via Pin1-proteomic analysis. The Prostate 72: 626-637.
47. Dutton-Regester K, Aoude LG, Nancarrow DJ, Stark MS, O'Connor L, et al. (2012) Identification of TFG (TRK-fused gene) as a putative metastatic melanoma tumor suppressor gene. Genes, Chromosomes and Cancer 51: 452-461.
48. Tiseo M, Gelsomino F, Bartolotti M, Bordi P, Bersanelli M, et al. (2011) Anaplastic lymphoma kinase as a new target for the treatment of non-small-cell lung cancer. Expert Review of Anticancer Therapy 11: 1677-1687.
49. Tojima Y, Fujimoto A, Delhase M, Chen Y, Hatakeyama S, et al. (2000) NAK is an I[kappa]B kinase-activating kinase. Nature 404: 778-782.
50. Fitzgerald KA, McWhirter SM, Faia KL, Rowe DC, Latz E, et al. (2003) IKK[epsi] and TBK1 are essential components of the IRF3 signaling pathway. Nat Immunol 4: 491-496. (Pubitemid 36592443)
51. Clark K, Takeuchi O, Akira S, Cohen P (2011) The TRAF-associated protein TANK facilitates cross-talk within the IκB kinase family during Toll-like receptor signaling. Proceedings of the National Academy of Sciences 108: 17093-17098.
52. Clark K, Peggie M, Plater L, Sorcek RJ, Young ERR, et al. (2011) Novel cross-talk within the IKK family controls innate immunity. Biochemical Journal 434: 93-104.
53. Chariot A, Leonardi A, Müller J, Bonif M, Brown K, et al. (2002) Association of the Adaptor TANK with the IκB Kinase (IKK) Regulator NEMO Connects IKK Complexes with IKK e and TBK1 Kinases. Journal of Biological Chemistry 277: 37029-37036.
54. Zhang L, Xu M, Scotti E, Chen ZJ, Tontonoz P (2013) Both K63 and K48 ubiquitin linkages signal lysosomal degradation of the LDL receptor. Journal of Lipid Research 54: 1410-1420.
55. Zhang Z, Bao M, Lu N, Weng L, Yuan B, et al. (2013) The E3 ubiquitin ligase TRIM21 negatively regulates the innate immune response to intracellular double-stranded DNA. Nat Immunol 14: 172-178.
56. Ben-Chetrit E, Chan EK, Sullivan KF, Tan EM (1988) A 52-kD protein is a novel component of the SS-A/Ro antigenic particle. The Journal of Experimental Medicine 167: 1560-1571.
57. Sjöstrand M, Brauner S, Kvarnström M, Wahren-Herlenius M, Espinosa A (2012) TRIM genes are part of the interferon signature observed in patients with primary Sjögren's syndrome. Annals of the Rheumatic Diseases 71: A81.