-
1
-
-
32944464648
-
Pathogen recognition and innate immunity
-
Akira S., Uematsu S., Takeuchi O. Pathogen recognition and innate immunity. Cell 2006, 124:783-801.
-
(2006)
Cell
, vol.124
, pp. 783-801
-
-
Akira, S.1
Uematsu, S.2
Takeuchi, O.3
-
2
-
-
80053590435
-
Orchestrating the interferon antiviral response through the mitochondrial antiviral signaling (MAVS) adapter
-
Belgnaoui S.M., Paz S., Hiscott J. Orchestrating the interferon antiviral response through the mitochondrial antiviral signaling (MAVS) adapter. Curr. Opin. Immunol. 2011, 23:564-572.
-
(2011)
Curr. Opin. Immunol.
, vol.23
, pp. 564-572
-
-
Belgnaoui, S.M.1
Paz, S.2
Hiscott, J.3
-
3
-
-
80054848955
-
TRIM proteins and cancer
-
Hatakeyama S. TRIM proteins and cancer. Nat. Rev. Cancer 2011, 11:792-804.
-
(2011)
Nat. Rev. Cancer
, vol.11
, pp. 792-804
-
-
Hatakeyama, S.1
-
4
-
-
54949126675
-
TRIM family proteins and their emerging roles in innate immunity
-
Ozato K., Shin D.M., Chang T.H., Morse H.C. TRIM family proteins and their emerging roles in innate immunity. Nat. Rev. Immunol. 2008, 8:849-860.
-
(2008)
Nat. Rev. Immunol.
, vol.8
, pp. 849-860
-
-
Ozato, K.1
Shin, D.M.2
Chang, T.H.3
Morse, H.C.4
-
5
-
-
34247341367
-
TRIM25 RING-finger E3 ubiquitin ligase is essential for RIG-I-mediated antiviral activity
-
Gack M.U., Shin Y.C., Joo C.H., Urano T., Liang C., Sun L., Takeuchi O., Akira S., Chen Z., Inoue S., Jung J.U. TRIM25 RING-finger E3 ubiquitin ligase is essential for RIG-I-mediated antiviral activity. Nature 2007, 446:916-920.
-
(2007)
Nature
, vol.446
, pp. 916-920
-
-
Gack, M.U.1
Shin, Y.C.2
Joo, C.H.3
Urano, T.4
Liang, C.5
Sun, L.6
Takeuchi, O.7
Akira, S.8
Chen, Z.9
Inoue, S.10
Jung, J.U.11
-
6
-
-
33645217490
-
The interferon-inducible ubiquitin-protein isopeptide ligase (E3) EFP also functions as an ISG15 E3 ligase
-
Zou W., Zhang D.E. The interferon-inducible ubiquitin-protein isopeptide ligase (E3) EFP also functions as an ISG15 E3 ligase. J. Biol. Chem. 2006, 281:3989-3994.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 3989-3994
-
-
Zou, W.1
Zhang, D.E.2
-
7
-
-
34248160996
-
The RBCC gene RFP2 (Leu5) encodes a novel transmembrane E3 ubiquitin ligase involved in ERAD
-
Lerner M., Corcoran M., Cepeda D., Nielsen M.L., Zubarev R., Ponten F., Uhlen M., Hober S., Grander D., Sangfelt O. The RBCC gene RFP2 (Leu5) encodes a novel transmembrane E3 ubiquitin ligase involved in ERAD. Mol. Biol. Cell 2007, 18:1670-1682.
-
(2007)
Mol. Biol. Cell
, vol.18
, pp. 1670-1682
-
-
Lerner, M.1
Corcoran, M.2
Cepeda, D.3
Nielsen, M.L.4
Zubarev, R.5
Ponten, F.6
Uhlen, M.7
Hober, S.8
Grander, D.9
Sangfelt, O.10
-
8
-
-
79960115308
-
Characterization of the oncogenic activity of the novel TRIM59 gene in mouse cancer models
-
Valiyeva F., Jiang F., Elmaadawi A., Moussa M., Yee S.P., Raptis L., Izawa J.I., Yang B.B., Greenberg N.M., Wang F., Xuan J.W. Characterization of the oncogenic activity of the novel TRIM59 gene in mouse cancer models. Mol. Cancer Ther. 2011, 10:1229-1240.
-
(2011)
Mol. Cancer Ther.
, vol.10
, pp. 1229-1240
-
-
Valiyeva, F.1
Jiang, F.2
Elmaadawi, A.3
Moussa, M.4
Yee, S.P.5
Raptis, L.6
Izawa, J.I.7
Yang, B.B.8
Greenberg, N.M.9
Wang, F.10
Xuan, J.W.11
-
9
-
-
0031872042
-
New experimental approaches in retrovirus-mediated expression screening
-
Kitamura T. New experimental approaches in retrovirus-mediated expression screening. Int. J. Hematol. 1998, 67:351-359.
-
(1998)
Int. J. Hematol.
, vol.67
, pp. 351-359
-
-
Kitamura, T.1
-
10
-
-
0347611095
-
Molecular machinery for non-vesicular trafficking of ceramide
-
Hanada K., Kumagai K., Yasuda S., Miura Y., Kawano M., Fukasawa M., Nishijima M. Molecular machinery for non-vesicular trafficking of ceramide. Nature 2003, 426:803-809.
-
(2003)
Nature
, vol.426
, pp. 803-809
-
-
Hanada, K.1
Kumagai, K.2
Yasuda, S.3
Miura, Y.4
Kawano, M.5
Fukasawa, M.6
Nishijima, M.7
-
11
-
-
8944251628
-
A central role for Stat3 in IL-6-induced regulation of growth and differentiation in M1 leukemia cells
-
Nakajima K., Yamanaka Y., Nakae K., Kojima H., Ichiba M., Kiuchi N., Kitaoka T., Fukada T., Hibi M., Hirano T. A central role for Stat3 in IL-6-induced regulation of growth and differentiation in M1 leukemia cells. EMBO J. 1996, 15:3651-3658.
-
(1996)
EMBO J.
, vol.15
, pp. 3651-3658
-
-
Nakajima, K.1
Yamanaka, Y.2
Nakae, K.3
Kojima, H.4
Ichiba, M.5
Kiuchi, N.6
Kitaoka, T.7
Fukada, T.8
Hibi, M.9
Hirano, T.10
-
12
-
-
33947414054
-
Establishment of a newly improved detection system for NF-kappaB activity
-
Matsuda M., Tsukiyama T., Bohgaki M., Nonomura K., Hatakeyama S. Establishment of a newly improved detection system for NF-kappaB activity. Immunol. Lett. 2007, 109:175-181.
-
(2007)
Immunol. Lett.
, vol.109
, pp. 175-181
-
-
Matsuda, M.1
Tsukiyama, T.2
Bohgaki, M.3
Nonomura, K.4
Hatakeyama, S.5
-
13
-
-
61349146561
-
TRAF6 and MEKK1 play a pivotal role in the RIG-I-like helicase antiviral pathway
-
Yoshida R., Takaesu G., Yoshida H., Okamoto F., Yoshioka T., Choi Y., Akira S., Kawai T., Yoshimura A., Kobayashi T. TRAF6 and MEKK1 play a pivotal role in the RIG-I-like helicase antiviral pathway. J. Biol. Chem. 2008, 283:36211-36220.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 36211-36220
-
-
Yoshida, R.1
Takaesu, G.2
Yoshida, H.3
Okamoto, F.4
Yoshioka, T.5
Choi, Y.6
Akira, S.7
Kawai, T.8
Yoshimura, A.9
Kobayashi, T.10
-
14
-
-
33947129099
-
Cytosolic signaling protein Ecsit also localizes to mitochondria where it interacts with chaperone NDUFAF1 and functions in complex I assembly
-
Vogel R.O., Janssen R.J., van den Brand M.A., Dieteren C.E., Verkaart S., Koopman W.J., Willems P.H., Pluk W., van den Heuvel L.P., Smeitink J.A., Nijtmans L.G. Cytosolic signaling protein Ecsit also localizes to mitochondria where it interacts with chaperone NDUFAF1 and functions in complex I assembly. Genes Dev. 2007, 21:615-624.
-
(2007)
Genes Dev.
, vol.21
, pp. 615-624
-
-
Vogel, R.O.1
Janssen, R.J.2
van den Brand, M.A.3
Dieteren, C.E.4
Verkaart, S.5
Koopman, W.J.6
Willems, P.H.7
Pluk, W.8
van den Heuvel, L.P.9
Smeitink, J.A.10
Nijtmans, L.G.11
-
15
-
-
0033567388
-
ECSIT is an evolutionarily conserved intermediate in the Toll/IL-1 signal transduction pathway
-
Kopp E., Medzhitov R., Carothers J., Xiao C., Douglas I., Janeway C.A., Ghosh S. ECSIT is an evolutionarily conserved intermediate in the Toll/IL-1 signal transduction pathway. Genes Dev. 1999, 13:2059-2071.
-
(1999)
Genes Dev.
, vol.13
, pp. 2059-2071
-
-
Kopp, E.1
Medzhitov, R.2
Carothers, J.3
Xiao, C.4
Douglas, I.5
Janeway, C.A.6
Ghosh, S.7
-
16
-
-
53349178089
-
STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling
-
Ishikawa H., Barber G.N. STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling. Nature 2008, 455:674-678.
-
(2008)
Nature
, vol.455
, pp. 674-678
-
-
Ishikawa, H.1
Barber, G.N.2
-
17
-
-
53349168904
-
The adaptor protein MITA links virus-sensing receptors to IRF3 transcription factor activation
-
Zhong B., Yang Y., Li S., Wang Y.Y., Li Y., Diao F., Lei C., He X., Zhang L., Tien P., Shu H.B. The adaptor protein MITA links virus-sensing receptors to IRF3 transcription factor activation. Immunity 2008, 29:538-550.
-
(2008)
Immunity
, vol.29
, pp. 538-550
-
-
Zhong, B.1
Yang, Y.2
Li, S.3
Wang, Y.Y.4
Li, Y.5
Diao, F.6
Lei, C.7
He, X.8
Zhang, L.9
Tien, P.10
Shu, H.B.11
-
18
-
-
66649109939
-
ERIS, an endoplasmic reticulum IFN stimulator, activates innate immune signaling through dimerization
-
Sun W., Li Y., Chen L., Chen H., You F., Zhou X., Zhou Y., Zhai Z., Chen D., Jiang Z. ERIS, an endoplasmic reticulum IFN stimulator, activates innate immune signaling through dimerization. Proc. Natl. Acad. Sci. USA 2009, 106:8653-8658.
-
(2009)
Proc. Natl. Acad. Sci. USA
, vol.106
, pp. 8653-8658
-
-
Sun, W.1
Li, Y.2
Chen, L.3
Chen, H.4
You, F.5
Zhou, X.6
Zhou, Y.7
Zhai, Z.8
Chen, D.9
Jiang, Z.10
-
19
-
-
79955532516
-
TLR signalling augments macrophage bactericidal activity through mitochondrial ROS
-
West A.P., Brodsky I.E., Rahner C., Woo D.K., Erdjument-Bromage H., Tempst P., Walsh M.C., Choi Y., Shadel G.S., Ghosh S. TLR signalling augments macrophage bactericidal activity through mitochondrial ROS. Nature 2011, 472:476-480.
-
(2011)
Nature
, vol.472
, pp. 476-480
-
-
West, A.P.1
Brodsky, I.E.2
Rahner, C.3
Woo, D.K.4
Erdjument-Bromage, H.5
Tempst, P.6
Walsh, M.C.7
Choi, Y.8
Shadel, G.S.9
Ghosh, S.10
-
20
-
-
40349116307
-
TRIM E3 ligases interfere with early and late stages of the retroviral life cycle
-
Uchil P.D., Quinlan B.D., Chan W.T., Luna J.M., Mothes W. TRIM E3 ligases interfere with early and late stages of the retroviral life cycle. PLoS Pathog. 2008, 4:e16.
-
(2008)
PLoS Pathog.
, vol.4
-
-
Uchil, P.D.1
Quinlan, B.D.2
Chan, W.T.3
Luna, J.M.4
Mothes, W.5
-
21
-
-
79955377543
-
TRIM5 is an innate immune sensor for the retrovirus capsid lattice
-
Pertel T., Hausmann S., Morger D., Zuger S., Guerra J., Lascano J., Reinhard C., Santoni F.A., Uchil P.D., Chatel L., Bisiaux A., Albert M.L., Strambio-De-Castillia C., Mothes W., Pizzato M., Grutter M.G., Luban J. TRIM5 is an innate immune sensor for the retrovirus capsid lattice. Nature 2011, 472:361-365.
-
(2011)
Nature
, vol.472
, pp. 361-365
-
-
Pertel, T.1
Hausmann, S.2
Morger, D.3
Zuger, S.4
Guerra, J.5
Lascano, J.6
Reinhard, C.7
Santoni, F.A.8
Uchil, P.D.9
Chatel, L.10
Bisiaux, A.11
Albert, M.L.12
Strambio-De-Castillia, C.13
Mothes, W.14
Pizzato, M.15
Grutter, M.G.16
Luban, J.17
-
22
-
-
82755190610
-
Tripartite motif 8 (TRIM8) modulates TNFalpha- and IL-1beta-triggered NF-kappaB activation by targeting TAK1 for K63-linked polyubiquitination
-
Li Q., Yan J., Mao A.P., Li C., Ran Y., Shu H.B., Wang Y.Y. Tripartite motif 8 (TRIM8) modulates TNFalpha- and IL-1beta-triggered NF-kappaB activation by targeting TAK1 for K63-linked polyubiquitination. Proc. Natl. Acad. Sci. USA 2011, 108:19341-19346.
-
(2011)
Proc. Natl. Acad. Sci. USA
, vol.108
, pp. 19341-19346
-
-
Li, Q.1
Yan, J.2
Mao, A.P.3
Li, C.4
Ran, Y.5
Shu, H.B.6
Wang, Y.Y.7
-
23
-
-
49649125136
-
The E3 ubiquitin ligase Ro52 negatively regulates IFN-beta production post-pathogen recognition by polyubiquitin-mediated degradation of IRF3
-
Higgs R., Ni Gabhann J., Ben Larbi N., Breen E.P., Fitzgerald K.A., Jefferies C.A. The E3 ubiquitin ligase Ro52 negatively regulates IFN-beta production post-pathogen recognition by polyubiquitin-mediated degradation of IRF3. J. Immunol. 2008, 181:1780-1786.
-
(2008)
J. Immunol.
, vol.181
, pp. 1780-1786
-
-
Higgs, R.1
Ni Gabhann, J.2
Ben Larbi, N.3
Breen, E.P.4
Fitzgerald, K.A.5
Jefferies, C.A.6
-
24
-
-
65449153592
-
TRIM21 is essential to sustain IFN regulatory factor 3 activation during antiviral response
-
Yang K., Shi H.X., Liu X.Y., Shan Y.F., Wei B., Chen S., Wang C. TRIM21 is essential to sustain IFN regulatory factor 3 activation during antiviral response. J. Immunol. 2009, 182:3782-3792.
-
(2009)
J. Immunol.
, vol.182
, pp. 3782-3792
-
-
Yang, K.1
Shi, H.X.2
Liu, X.Y.3
Shan, Y.F.4
Wei, B.5
Chen, S.6
Wang, C.7
-
25
-
-
30744475939
-
The Ret finger protein inhibits signaling mediated by the noncanonical and canonical IkappaB kinase family members
-
Zha J., Han K.J., Xu L.G., He W., Zhou Q., Chen D., Zhai Z., Shu H.B. The Ret finger protein inhibits signaling mediated by the noncanonical and canonical IkappaB kinase family members. J. Immunol. 2006, 176:1072-1080.
-
(2006)
J. Immunol.
, vol.176
, pp. 1072-1080
-
-
Zha, J.1
Han, K.J.2
Xu, L.G.3
He, W.4
Zhou, Q.5
Chen, D.6
Zhai, Z.7
Shu, H.B.8
-
26
-
-
40949163764
-
TRIM30 alpha negatively regulates TLR-mediated NF-kappa B activation by targeting TAB2 and TAB3 for degradation
-
Shi M., Deng W., Bi E., Mao K., Ji Y., Lin G., Wu X., Tao Z., Li Z., Cai X., Sun S., Xiang C., Sun B. TRIM30 alpha negatively regulates TLR-mediated NF-kappa B activation by targeting TAB2 and TAB3 for degradation. Nat. Immunol. 2008, 9:369-377.
-
(2008)
Nat. Immunol.
, vol.9
, pp. 369-377
-
-
Shi, M.1
Deng, W.2
Bi, E.3
Mao, K.4
Ji, Y.5
Lin, G.6
Wu, X.7
Tao, Z.8
Li, Z.9
Cai, X.10
Sun, S.11
Xiang, C.12
Sun, B.13
-
27
-
-
78650214109
-
The ubiquitin ligase TRIM56 regulates innate immune responses to intracellular double-stranded DNA
-
Tsuchida T., Zou J., Saitoh T., Kumar H., Abe T., Matsuura Y., Kawai T., Akira S. The ubiquitin ligase TRIM56 regulates innate immune responses to intracellular double-stranded DNA. Immunity 2010, 33:765-776.
-
(2010)
Immunity
, vol.33
, pp. 765-776
-
-
Tsuchida, T.1
Zou, J.2
Saitoh, T.3
Kumar, H.4
Abe, T.5
Matsuura, Y.6
Kawai, T.7
Akira, S.8
-
28
-
-
84862791627
-
TRIM13 regulates ER stress induced autophagy and clonogenic ability of the cells
-
Tomar D., Singh R., Singh A.K., Pandya C.D. TRIM13 regulates ER stress induced autophagy and clonogenic ability of the cells. Biochim. Biophys. Acta 1823, 2012:316-326.
-
(1823)
Biochim. Biophys. Acta
, vol.2012
, pp. 316-326
-
-
Tomar, D.1
Singh, R.2
Singh, A.K.3
Pandya, C.D.4
|