메뉴 건너뛰기




Volumn 111, Issue , 2017, Pages 281-293

Linking lipid peroxidation and neuropsychiatric disorders: focus on 4-hydroxy-2-nonenal

Author keywords

4 hydroxy 2 nonenal; bipolar disorders; depression; Huntington's disease; neuropsychiatric disorders; Parkinson's disease; schizophrenia

Indexed keywords

4 HYDROXYNONENAL; FREE RADICAL; METAL ION; 4-HYDROXY-2-NONENAL; ALDEHYDE; IRON; NEUROPROTECTIVE AGENT;

EID: 85009505654     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2016.12.046     Document Type: Review
Times cited : (59)

References (218)
  • 1
    • 80052190938 scopus 로고    scopus 로고
    • Principles and therapeutic relevance for targeting mitochondria in aging and neurodegenerative diseases
    • Serviddio, G., Romano, A.D., Cassano, T., Bellanti, F., Altomare, E., Vendemiale, G., Principles and therapeutic relevance for targeting mitochondria in aging and neurodegenerative diseases. Curr. Pharm. Des. 17:20 (2011), 2036–2055.
    • (2011) Curr. Pharm. Des. , vol.17 , Issue.20 , pp. 2036-2055
    • Serviddio, G.1    Romano, A.D.2    Cassano, T.3    Bellanti, F.4    Altomare, E.5    Vendemiale, G.6
  • 2
    • 84923685347 scopus 로고    scopus 로고
    • Mitochondria: from cell death executioners to regulators of cell differentiation
    • Kasahara, A., Scorrano, L., Mitochondria: from cell death executioners to regulators of cell differentiation. Trends Cell. Biol. 24:12 (2014), 761–770.
    • (2014) Trends Cell. Biol. , vol.24 , Issue.12 , pp. 761-770
    • Kasahara, A.1    Scorrano, L.2
  • 3
    • 84959377278 scopus 로고    scopus 로고
    • Glutamate and Miochondria: Two Prominent Players in the Oxidative Stress‐Induced Neurodegeneration
    • Cassano, T., Pace, L., Bedse, G., Lavecchia, A.M., De Marco, F., Gaetani, S., Serviddio, G., Glutamate and Miochondria: Two Prominent Players in the Oxidative Stress‐Induced Neurodegeneration. Curr. Alzheimer Res. 13:2 (2016), 185–197.
    • (2016) Curr. Alzheimer Res. , vol.13 , Issue.2 , pp. 185-197
    • Cassano, T.1    Pace, L.2    Bedse, G.3    Lavecchia, A.M.4    De Marco, F.5    Gaetani, S.6    Serviddio, G.7
  • 4
    • 65949121134 scopus 로고    scopus 로고
    • Oxidative stress and neurodegenerative diseases: a review of upstream and downstream antioxidant therapeutic options
    • Uttara, B., Singh, A., Zamboni, P., Mahajan, R., Oxidative stress and neurodegenerative diseases: a review of upstream and downstream antioxidant therapeutic options. Curr. Neuropharmacol. 7:1 (2009), 65–74.
    • (2009) Curr. Neuropharmacol. , vol.7 , Issue.1 , pp. 65-74
    • Uttara, B.1    Singh, A.2    Zamboni, P.3    Mahajan, R.4
  • 5
    • 2342562466 scopus 로고    scopus 로고
    • Mitochondria, synaptic plasticity, and schizophrenia
    • Ben-Shachar, D., Laifenfeld, D., Mitochondria, synaptic plasticity, and schizophrenia. Int. Rev. Neurobiol. 59 (2004), 273–296.
    • (2004) Int. Rev. Neurobiol. , vol.59 , pp. 273-296
    • Ben-Shachar, D.1    Laifenfeld, D.2
  • 6
    • 0141741347 scopus 로고    scopus 로고
    • Parkinson's disease: mechanisms and models
    • Dauer, W., Przedborski, S., Parkinson's disease: mechanisms and models. Neuron 39:6 (2003), 889–909.
    • (2003) Neuron , vol.39 , Issue.6 , pp. 889-909
    • Dauer, W.1    Przedborski, S.2
  • 7
    • 79960858815 scopus 로고    scopus 로고
    • Antioxidants, redox signaling, and pathophysiology in schizophrenia: an integrative view
    • Yao, J.K., Keshavan, M.S., Antioxidants, redox signaling, and pathophysiology in schizophrenia: an integrative view. Antioxid. Redox Signal. 15:7 (2011), 2011–2035.
    • (2011) Antioxid. Redox Signal. , vol.15 , Issue.7 , pp. 2011-2035
    • Yao, J.K.1    Keshavan, M.S.2
  • 8
    • 79952959359 scopus 로고    scopus 로고
    • Mitochondrial dysfunction and pathology in bipolar disorder and schizophrenia
    • Clay, H.B., Sillivan, S., Konradi, C., Mitochondrial dysfunction and pathology in bipolar disorder and schizophrenia. Int. J. Dev. Neurosci. 29:3 (2011), 311–324.
    • (2011) Int. J. Dev. Neurosci. , vol.29 , Issue.3 , pp. 311-324
    • Clay, H.B.1    Sillivan, S.2    Konradi, C.3
  • 11
    • 84870895644 scopus 로고    scopus 로고
    • A fresh look at complex I in microarray data: clues to understanding disease- specific mitochondrial alterations in bipolar disorder
    • Scola, G., Kim, H.K., Young, L.T., Andreazza, A.C., A fresh look at complex I in microarray data: clues to understanding disease- specific mitochondrial alterations in bipolar disorder. Biol. Psychiatry 73:2 (2013), e4–e5.
    • (2013) Biol. Psychiatry , vol.73 , Issue.2 , pp. e4-e5
    • Scola, G.1    Kim, H.K.2    Young, L.T.3    Andreazza, A.C.4
  • 12
    • 0029439509 scopus 로고
    • Oxidative stress: the paradox of aerobic life
    • Davies, K.J., Oxidative stress: the paradox of aerobic life. Biochem. Soc. Symp. 61 (1995), 1–31.
    • (1995) Biochem. Soc. Symp. , vol.61 , pp. 1-31
    • Davies, K.J.1
  • 13
    • 0346788896 scopus 로고    scopus 로고
    • Mitochondrial matrix reactive oxygen species production is very sensitive to mild uncoupling
    • Miwa, S., Brand, M.D., Mitochondrial matrix reactive oxygen species production is very sensitive to mild uncoupling. Biochem. Soc. Trans. 31:Pt 6 (2003), 1300–1301.
    • (2003) Biochem. Soc. Trans. , vol.31 , pp. 1300-1301
    • Miwa, S.1    Brand, M.D.2
  • 15
    • 85015216825 scopus 로고    scopus 로고
    • Reactive Oxygen Species: Physiological and Physiopathological Effects on Synaptic Plasticity
    • Beckhauser, T.F., Francis-Oliveira, J., De Pasquale, R., Reactive Oxygen Species: Physiological and Physiopathological Effects on Synaptic Plasticity. J. Exp. Neurosci. 10:Suppl 1 (2016), 23–48.
    • (2016) J. Exp. Neurosci. , vol.10 , pp. 23-48
    • Beckhauser, T.F.1    Francis-Oliveira, J.2    De Pasquale, R.3
  • 16
    • 77956234404 scopus 로고    scopus 로고
    • Reactive oxygen species and alpha,beta-unsaturated aldehydes as second messengers in signal transduction
    • Forman, H.J., Reactive oxygen species and alpha,beta-unsaturated aldehydes as second messengers in signal transduction. Ann. N. Y. Acad. Sci. 1203 (2010), 35–44.
    • (2010) Ann. N. Y. Acad. Sci. , vol.1203 , pp. 35-44
    • Forman, H.J.1
  • 17
    • 84901917562 scopus 로고    scopus 로고
    • Lipid peroxidation: production, metabolism, and signaling mechanisms of malondialdehyde and 4-hydroxy-2-nonenal
    • Ayala, A., Muñoz, M.F., Argüelles, S., Lipid peroxidation: production, metabolism, and signaling mechanisms of malondialdehyde and 4-hydroxy-2-nonenal. Oxid. Med. Cell. Longev. 8 (2014), 360–438.
    • (2014) Oxid. Med. Cell. Longev. , vol.8 , pp. 360-438
    • Ayala, A.1    Muñoz, M.F.2    Argüelles, S.3
  • 18
    • 0035584857 scopus 로고    scopus 로고
    • Reactive oxygen species, antioxidants, and the mammalian thioredoxin system
    • Nordberg, J., Arnér, E.S., Reactive oxygen species, antioxidants, and the mammalian thioredoxin system. Free Radic. Biol. Med. 31:11 (2001), 1287–1312.
    • (2001) Free Radic. Biol. Med. , vol.31 , Issue.11 , pp. 1287-1312
    • Nordberg, J.1    Arnér, E.S.2
  • 19
    • 0029760957 scopus 로고    scopus 로고
    • Redox regulation of transcriptional activators
    • Sun, Y., Oberley, L.W., Redox regulation of transcriptional activators. Free Radic. Biol. Med. 21:3 (1996), 335–348.
    • (1996) Free Radic. Biol. Med. , vol.21 , Issue.3 , pp. 335-348
    • Sun, Y.1    Oberley, L.W.2
  • 20
    • 0036867895 scopus 로고    scopus 로고
    • Oxidation of biological systems: oxidative stress phenomena, antioxidants, redox reactions, and methods for their quantification
    • Kohen, R., Nyska, A., Oxidation of biological systems: oxidative stress phenomena, antioxidants, redox reactions, and methods for their quantification. Toxicol. Pathol. 30:6 (2002), 620–650.
    • (2002) Toxicol. Pathol. , vol.30 , Issue.6 , pp. 620-650
    • Kohen, R.1    Nyska, A.2
  • 22
    • 0027459113 scopus 로고
    • Mechanisms and biological relevance of lipid peroxidation initiation
    • Dix, T.A., Aikens, J., Mechanisms and biological relevance of lipid peroxidation initiation. Chem. Res. Toxicol. 6:1 (1993), 2–18.
    • (1993) Chem. Res. Toxicol. , vol.6 , Issue.1 , pp. 2-18
    • Dix, T.A.1    Aikens, J.2
  • 23
    • 45249124663 scopus 로고    scopus 로고
    • 4-hydroxynonenal: a membrane lipid oxidation product of medicinal interest
    • Poli, G., Schaur, R.J., Siems, W.G., Leonarduzzi, G., 4-hydroxynonenal: a membrane lipid oxidation product of medicinal interest. Med. Res. Rev. 28:4 (2008), 569–631.
    • (2008) Med. Res. Rev. , vol.28 , Issue.4 , pp. 569-631
    • Poli, G.1    Schaur, R.J.2    Siems, W.G.3    Leonarduzzi, G.4
  • 24
    • 0025814980 scopus 로고
    • Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes
    • Esterbauer, H., Schaur, R.J., Zollner, H., Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes. Free Radic. Biol. Med. 11:1 (1991), 81–128.
    • (1991) Free Radic. Biol. Med. , vol.11 , Issue.1 , pp. 81-128
    • Esterbauer, H.1    Schaur, R.J.2    Zollner, H.3
  • 25
    • 67649949078 scopus 로고    scopus 로고
    • Products of oxidative stress inhibit aldehyde oxidation and reduction pathways in dopamine catabolism yielding elevated levels of a reactive intermediate
    • Jinsmaa, Y., Florang, V.R., Rees, J.N., Anderson, D.G., Strack, S., Doorn, J.A., Products of oxidative stress inhibit aldehyde oxidation and reduction pathways in dopamine catabolism yielding elevated levels of a reactive intermediate. Chem. Res. Toxicol. 22:5 (2009), 835–841.
    • (2009) Chem. Res. Toxicol. , vol.22 , Issue.5 , pp. 835-841
    • Jinsmaa, Y.1    Florang, V.R.2    Rees, J.N.3    Anderson, D.G.4    Strack, S.5    Doorn, J.A.6
  • 26
    • 84887620267 scopus 로고    scopus 로고
    • Cell death and diseases related to oxidative stress: 4-hydroxynonenal (HNE) in the balance
    • Dalleau, S., Baradat, M., Guéraud, F., Huc, L., Cell death and diseases related to oxidative stress: 4-hydroxynonenal (HNE) in the balance. Cell Death Differ. 20:12 (2013), 1615–1630.
    • (2013) Cell Death Differ. , vol.20 , Issue.12 , pp. 1615-1630
    • Dalleau, S.1    Baradat, M.2    Guéraud, F.3    Huc, L.4
  • 27
    • 0031693176 scopus 로고    scopus 로고
    • Lipid peroxidation and biogenic aldehydes: from the identification of 4-hydroxynonenal to further achievements in biopathology
    • Comporti, M., Lipid peroxidation and biogenic aldehydes: from the identification of 4-hydroxynonenal to further achievements in biopathology. Free Radic. Res. 28:6 (1998), 623–635.
    • (1998) Free Radic. Res. , vol.28 , Issue.6 , pp. 623-635
    • Comporti, M.1
  • 28
    • 0032422401 scopus 로고    scopus 로고
    • Immunohistochemical and ELISA assays for biomarkers of oxidative stress in aging and disease
    • Onorato, J.M., Thorpe, S.R., Baynes, J.W., Immunohistochemical and ELISA assays for biomarkers of oxidative stress in aging and disease. Ann. N. Y. Acad. Sci. 854 (1998), 277–290.
    • (1998) Ann. N. Y. Acad. Sci. , vol.854 , pp. 277-290
    • Onorato, J.M.1    Thorpe, S.R.2    Baynes, J.W.3
  • 29
    • 0027686249 scopus 로고
    • Oxidative stress, glutamate, and neurodegenerative disorders
    • Coyle, J.T., Puttfarcken, P., Oxidative stress, glutamate, and neurodegenerative disorders. Science 262:5134 (1993), 689–695.
    • (1993) Science , vol.262 , Issue.5134 , pp. 689-695
    • Coyle, J.T.1    Puttfarcken, P.2
  • 30
    • 84866848255 scopus 로고    scopus 로고
    • 4-Hydroxy-2-nonenal, a reactive product of lipid peroxidation, and neurodegenerative diseases: a toxic combination illuminated by redox proteomics studies
    • Perluigi, M., Coccia, R., Butterfield, D.A., 4-Hydroxy-2-nonenal, a reactive product of lipid peroxidation, and neurodegenerative diseases: a toxic combination illuminated by redox proteomics studies. Antioxid. Redox Signal. 17:11 (2012), 1590–1609.
    • (2012) Antioxid. Redox Signal. , vol.17 , Issue.11 , pp. 1590-1609
    • Perluigi, M.1    Coccia, R.2    Butterfield, D.A.3
  • 31
    • 84884877254 scopus 로고    scopus 로고
    • Lipid peroxidation triggers neurodegeneration: a redox proteomics view into the Alzheimer disease brain
    • Sultana, R., Perluigi, M., Allan Butterfield, D., Lipid peroxidation triggers neurodegeneration: a redox proteomics view into the Alzheimer disease brain. Free Radic. Biol. Med. 62 (2013), 157–169.
    • (2013) Free Radic. Biol. Med. , vol.62 , pp. 157-169
    • Sultana, R.1    Perluigi, M.2    Allan Butterfield, D.3
  • 32
    • 0043172509 scopus 로고    scopus 로고
    • Basic aspects of the biochemical reactivity of 4-hydroxynonenal
    • Schaur, R.J., Basic aspects of the biochemical reactivity of 4-hydroxynonenal. Mol. Asp. Med. 24:4–5 (2003), 149–159.
    • (2003) Mol. Asp. Med. , vol.24 , Issue.4-5 , pp. 149-159
    • Schaur, R.J.1
  • 36
    • 27344458546 scopus 로고    scopus 로고
    • Activation of microglial NADPH oxidase is synergistic with glial iNOS expression in inducing neuronal death: a dual-key mechanism of inflammatory neurodegeneration
    • Mander, P., Brown, G.C., Activation of microglial NADPH oxidase is synergistic with glial iNOS expression in inducing neuronal death: a dual-key mechanism of inflammatory neurodegeneration. J. Neuroinflamm., 2, 2005, 20.
    • (2005) J. Neuroinflamm. , vol.2 , pp. 20
    • Mander, P.1    Brown, G.C.2
  • 37
    • 77950858637 scopus 로고    scopus 로고
    • Microglia in neurodegenerative disease
    • Perry, V.H., Nicoll, J.A., Holmes, C., Microglia in neurodegenerative disease. Nat. Rev. Neurol. 6:4 (2010), 193–201.
    • (2010) Nat. Rev. Neurol. , vol.6 , Issue.4 , pp. 193-201
    • Perry, V.H.1    Nicoll, J.A.2    Holmes, C.3
  • 38
    • 85022133313 scopus 로고    scopus 로고
    • Role of 4-hydroxy-2-nonenal (HNE) in the pathogenesis of alzheimer disease and other selected age-related neurodegenerative disorders
    • (pii: S0891-5849(16)(30980-7)
    • Di Domenico, F., Tramutola, A., Butterfield, D.A., Role of 4-hydroxy-2-nonenal (HNE) in the pathogenesis of alzheimer disease and other selected age-related neurodegenerative disorders. Free Radic. Biol. Med., 2016 (pii: S0891-5849(16)(30980-7).
    • (2016) Free Radic. Biol. Med.
    • Di Domenico, F.1    Tramutola, A.2    Butterfield, D.A.3
  • 39
    • 0031020476 scopus 로고    scopus 로고
    • A role for 4-hydroxynonenal, an aldehydic product of lipid peroxidation, in disruption of ion homeostasis and neuronal death induced by amyloid beta-peptide
    • Mark, R.J., Lovell, M.A., Markesbery, W.R., Uchida, K., Mattson, M.P., A role for 4-hydroxynonenal, an aldehydic product of lipid peroxidation, in disruption of ion homeostasis and neuronal death induced by amyloid beta-peptide. J. Neurochem. 68:1 (1997), 255–264.
    • (1997) J. Neurochem. , vol.68 , Issue.1 , pp. 255-264
    • Mark, R.J.1    Lovell, M.A.2    Markesbery, W.R.3    Uchida, K.4    Mattson, M.P.5
  • 40
    • 0031020993 scopus 로고    scopus 로고
    • Amyloid beta-peptide impairs glucose transport in hippocampal and cortical neurons: involvement of membrane lipid peroxidation
    • Mark, R.J., Pang, Z., Geddes, J.W., Uchida, K., Mattson, M.P., Amyloid beta-peptide impairs glucose transport in hippocampal and cortical neurons: involvement of membrane lipid peroxidation. J. Neurosci. 17:3 (1997), 1046–1054.
    • (1997) J. Neurosci. , vol.17 , Issue.3 , pp. 1046-1054
    • Mark, R.J.1    Pang, Z.2    Geddes, J.W.3    Uchida, K.4    Mattson, M.P.5
  • 41
    • 77952095680 scopus 로고    scopus 로고
    • Lipopolysaccharide-activated microglia induce dysfunction of the blood-brain barrier in rat microvascular endothelial cells co-cultured with microglia
    • Sumi, N., Nishioku, T., Takata, F., Matsumoto, J., Watanabe, T., Shuto, H., Yamauchi, A., Dohgu, S., Kataoka, Y., Lipopolysaccharide-activated microglia induce dysfunction of the blood-brain barrier in rat microvascular endothelial cells co-cultured with microglia. Cell. Mol. Neurobiol. 30:2 (2010), 247–253.
    • (2010) Cell. Mol. Neurobiol. , vol.30 , Issue.2 , pp. 247-253
    • Sumi, N.1    Nishioku, T.2    Takata, F.3    Matsumoto, J.4    Watanabe, T.5    Shuto, H.6    Yamauchi, A.7    Dohgu, S.8    Kataoka, Y.9
  • 42
    • 84891148121 scopus 로고    scopus 로고
    • Role of TGF-β in Survival of Phagocytizing Microglia: Autocrine Suppression of TNF‐α Production and Oxidative Stress
    • Ryu, K.Y., Cho, G.S., Piao, H.Z., Kim, W.K., Role of TGF-β in Survival of Phagocytizing Microglia: Autocrine Suppression of TNF‐α Production and Oxidative Stress. Exp. Neurobiol. 21:4 (2012), 151–157.
    • (2012) Exp. Neurobiol. , vol.21 , Issue.4 , pp. 151-157
    • Ryu, K.Y.1    Cho, G.S.2    Piao, H.Z.3    Kim, W.K.4
  • 44
    • 0035900210 scopus 로고    scopus 로고
    • 4-Hydroxynonenal impairs the permeability of an in vitro rat blood-brain barrier
    • Mertsch, K., Blasig, I., Grune, T., 4-Hydroxynonenal impairs the permeability of an in vitro rat blood-brain barrier. Neurosci. Lett. 314:3 (2001), 135–138.
    • (2001) Neurosci. Lett. , vol.314 , Issue.3 , pp. 135-138
    • Mertsch, K.1    Blasig, I.2    Grune, T.3
  • 45
    • 33845629703 scopus 로고    scopus 로고
    • Redox regulation of 4-hydroxy-2-nonenal-mediated endothelial barrier dysfunction by focal adhesion, adherens, and tight junction proteins
    • Usatyuk, P.V., Parinandi, N.L., Natarajan, V., Redox regulation of 4-hydroxy-2-nonenal-mediated endothelial barrier dysfunction by focal adhesion, adherens, and tight junction proteins. J. Biol. Chem. 281:46 (2006), 35554–35566.
    • (2006) J. Biol. Chem. , vol.281 , Issue.46 , pp. 35554-35566
    • Usatyuk, P.V.1    Parinandi, N.L.2    Natarajan, V.3
  • 48
    • 84857833776 scopus 로고    scopus 로고
    • Cell signalling by reactive lipid species: new concepts and molecular mechanisms
    • Higdon, A., Diers, A.R., Oh, J.Y., Landar, A., Darley-Usmar, V.M., Cell signalling by reactive lipid species: new concepts and molecular mechanisms. Biochem. J. 442:3 (2012), 453–464.
    • (2012) Biochem. J. , vol.442 , Issue.3 , pp. 453-464
    • Higdon, A.1    Diers, A.R.2    Oh, J.Y.3    Landar, A.4    Darley-Usmar, V.M.5
  • 49
    • 85012054817 scopus 로고    scopus 로고
    • 4-Hydroxy-nonenal-A Bioactive Lipid Peroxidation Product
    • Schaur, R.J., Siems, W., Bresgen, N., Eckl, P.M., 4-Hydroxy-nonenal-A Bioactive Lipid Peroxidation Product. Biomolecules 5:4 (2015), 2247–2337.
    • (2015) Biomolecules , vol.5 , Issue.4 , pp. 2247-2337
    • Schaur, R.J.1    Siems, W.2    Bresgen, N.3    Eckl, P.M.4
  • 50
    • 84886947267 scopus 로고    scopus 로고
    • Pathophysiological relevance of aldehydic protein modifications
    • Zarkovic, N., Cipak, A., Jaganjac, M., Borovic, S., Zarkovic, K., Pathophysiological relevance of aldehydic protein modifications. J. Proteom. 92 (2013), 239–247.
    • (2013) J. Proteom. , vol.92 , pp. 239-247
    • Zarkovic, N.1    Cipak, A.2    Jaganjac, M.3    Borovic, S.4    Zarkovic, K.5
  • 51
    • 84886543611 scopus 로고    scopus 로고
    • Hormesis in aging and neurodegeneration-a prodigy awaiting dissection
    • Mao, L., Franke, J., Hormesis in aging and neurodegeneration-a prodigy awaiting dissection. Int. J. Mol. Sci. 14:7 (2013), 13109–13128.
    • (2013) Int. J. Mol. Sci. , vol.14 , Issue.7 , pp. 13109-13128
    • Mao, L.1    Franke, J.2
  • 52
    • 7444224175 scopus 로고    scopus 로고
    • Signaling kinases modulated by 4-hydroxynonenal
    • Leonarduzzi, G., Robbesyn, F., Poli, G., Signaling kinases modulated by 4-hydroxynonenal. Free Radic. Biol. Med. 37:11 (2004), 1694–1702.
    • (2004) Free Radic. Biol. Med. , vol.37 , Issue.11 , pp. 1694-1702
    • Leonarduzzi, G.1    Robbesyn, F.2    Poli, G.3
  • 53
    • 77952548782 scopus 로고    scopus 로고
    • How increased oxidative stress promotes longevity and metabolic health: the concept of mitochondrial hormesis (mitohormesis)
    • Ristow, M., Zarse, K., How increased oxidative stress promotes longevity and metabolic health: the concept of mitochondrial hormesis (mitohormesis). Exp. Gerontol. 45:6 (2010), 410–418.
    • (2010) Exp. Gerontol. , vol.45 , Issue.6 , pp. 410-418
    • Ristow, M.1    Zarse, K.2
  • 54
    • 0033304082 scopus 로고    scopus 로고
    • Cellular signal adaptation with damage control at low doses versus the predominance of DNA damage at high doses
    • Feinendegen, L.E., Bond, V.P., Sondhaus, C.A., Altman, K.I., Cellular signal adaptation with damage control at low doses versus the predominance of DNA damage at high doses. C. R. Acad. Sci. III 322:2–3 (1999), 245–251.
    • (1999) C. R. Acad. Sci. III , vol.322 , Issue.2-3 , pp. 245-251
    • Feinendegen, L.E.1    Bond, V.P.2    Sondhaus, C.A.3    Altman, K.I.4
  • 55
    • 0033498958 scopus 로고    scopus 로고
    • Effect of antioxidant supplementation on the adaptive response of human skin fibroblasts to UV-induced oxidative stress
    • Jones, S.A., McArdle, F., Jack, C.I., Jackson, M.J., Effect of antioxidant supplementation on the adaptive response of human skin fibroblasts to UV-induced oxidative stress. Redox Rep. 4:6 (1999), 291–299.
    • (1999) Redox Rep. , vol.4 , Issue.6 , pp. 291-299
    • Jones, S.A.1    McArdle, F.2    Jack, C.I.3    Jackson, M.J.4
  • 56
    • 0033845938 scopus 로고    scopus 로고
    • Deacylation and reacylation of neural membrane glycerophospholipids
    • Farooqui, A.A., Horrocks, L.A., Farooqui, T., Deacylation and reacylation of neural membrane glycerophospholipids. J. Mol. Neurosci. 14:3 (2000), 123–135.
    • (2000) J. Mol. Neurosci. , vol.14 , Issue.3 , pp. 123-135
    • Farooqui, A.A.1    Horrocks, L.A.2    Farooqui, T.3
  • 57
    • 7444224175 scopus 로고    scopus 로고
    • Signaling kinases modulated by 4-hydroxynonenal
    • Leonarduzzi, G., Robbesyn, F., Poli, G., Signaling kinases modulated by 4-hydroxynonenal. Free Radic. Biol. Med. 37:11 (2004), 1694–1702.
    • (2004) Free Radic. Biol. Med. , vol.37 , Issue.11 , pp. 1694-1702
    • Leonarduzzi, G.1    Robbesyn, F.2    Poli, G.3
  • 58
    • 1642396537 scopus 로고    scopus 로고
    • Role of Nrf2 in the regulation of CD36 and stress protein expression in murine macrophages: activation by oxidatively modified LDL and 4-hydroxynonenal
    • Ishii, T., Itoh, K., Ruiz, E., Leake, D.S., Unoki, H., Yamamoto, M., Mann, G.E., Role of Nrf2 in the regulation of CD36 and stress protein expression in murine macrophages: activation by oxidatively modified LDL and 4-hydroxynonenal. Circ. Res. 94:5 (2004), 609–616.
    • (2004) Circ. Res. , vol.94 , Issue.5 , pp. 609-616
    • Ishii, T.1    Itoh, K.2    Ruiz, E.3    Leake, D.S.4    Unoki, H.5    Yamamoto, M.6    Mann, G.E.7
  • 59
    • 13844272420 scopus 로고    scopus 로고
    • 4-Hydroxynonenal increases gamma-glutamyl transpeptidase gene expression through mitogen-activated protein kinase pathways
    • Zhang, H., Dickinson, D.A., Liu, R.M., Forman, H.J., 4-Hydroxynonenal increases gamma-glutamyl transpeptidase gene expression through mitogen-activated protein kinase pathways. Free Radic. Biol. Med. 38:4 (2005), 463–471.
    • (2005) Free Radic. Biol. Med. , vol.38 , Issue.4 , pp. 463-471
    • Zhang, H.1    Dickinson, D.A.2    Liu, R.M.3    Forman, H.J.4
  • 60
    • 32044466295 scopus 로고    scopus 로고
    • 4-Hydroxynonenal induces rat gamma-glutamyl transpeptidase through mitogen-activated protein kinase-mediated electrophile response element/nuclear factor erythroid 2-related factor 2 signaling
    • Zhang, H., Liu, H., Iles, K.E., Liu, R.M., Postlethwait, E.M., Laperche, Y., Forman, H.J., 4-Hydroxynonenal induces rat gamma-glutamyl transpeptidase through mitogen-activated protein kinase-mediated electrophile response element/nuclear factor erythroid 2-related factor 2 signaling. Am. J. Respir. Cell. Mol. Biol. 34:2 (2006), 174–181.
    • (2006) Am. J. Respir. Cell. Mol. Biol. , vol.34 , Issue.2 , pp. 174-181
    • Zhang, H.1    Liu, H.2    Iles, K.E.3    Liu, R.M.4    Postlethwait, E.M.5    Laperche, Y.6    Forman, H.J.7
  • 63
    • 29644437160 scopus 로고    scopus 로고
    • 4-Hydroxynonenal induces adaptive response and enhances PC12 cell tolerance primarily through induction of thioredoxin reductase 1 via activation of Nrf2
    • Chen, Z.H., Saito, Y., Yoshida, Y., Sekine, A., Noguchi, N., Niki, E., 4-Hydroxynonenal induces adaptive response and enhances PC12 cell tolerance primarily through induction of thioredoxin reductase 1 via activation of Nrf2. J. Biol. Chem. 280:51 (2005), 41921–41927.
    • (2005) J. Biol. Chem. , vol.280 , Issue.51 , pp. 41921-41927
    • Chen, Z.H.1    Saito, Y.2    Yoshida, Y.3    Sekine, A.4    Noguchi, N.5    Niki, E.6
  • 64
    • 30644475949 scopus 로고    scopus 로고
    • Adaptive response induced by lipid peroxidation products in cell cultures
    • Chen, Z.H., Yoshida, Y., Saito, Y., Noguchi, N., Niki, E., Adaptive response induced by lipid peroxidation products in cell cultures. FEBS Lett. 580:2 (2006), 479–483.
    • (2006) FEBS Lett. , vol.580 , Issue.2 , pp. 479-483
    • Chen, Z.H.1    Yoshida, Y.2    Saito, Y.3    Noguchi, N.4    Niki, E.5
  • 66
    • 84899581041 scopus 로고    scopus 로고
    • The role of antioxidants in skin cancer prevention and treatment
    • Godic, A., Poljšak, B., Adamic, M., Dahmane, R., The role of antioxidants in skin cancer prevention and treatment. Oxid. Med. Cell. Longev., 2014, 2014, 860479.
    • (2014) Oxid. Med. Cell. Longev. , vol.2014 , pp. 860479
    • Godic, A.1    Poljšak, B.2    Adamic, M.3    Dahmane, R.4
  • 67
    • 77957363916 scopus 로고    scopus 로고
    • Exogenous antioxidants–Double-edged swords in cellular redox state: health beneficial effects at physiologic doses versus deleterious effects at high doses
    • Bouayed, J., Bohn, T., Exogenous antioxidants–Double-edged swords in cellular redox state: health beneficial effects at physiologic doses versus deleterious effects at high doses. Oxid. Med. Cell. Longev. 3:4 (2010), 228–237.
    • (2010) Oxid. Med. Cell. Longev. , vol.3 , Issue.4 , pp. 228-237
    • Bouayed, J.1    Bohn, T.2
  • 68
    • 84983432945 scopus 로고    scopus 로고
    • Natural Polyphenols for Prevention and Treatment of Cancer
    • Zhou, Y., Zheng, J., Li, Y., Xu, D.P., Li, S., Chen, Y.M., Li, H.B., Natural Polyphenols for Prevention and Treatment of Cancer. Nutrients, 8(8), 2016, E515.
    • (2016) Nutrients , vol.8 , Issue.8 , pp. E515
    • Zhou, Y.1    Zheng, J.2    Li, Y.3    Xu, D.P.4    Li, S.5    Chen, Y.M.6    Li, H.B.7
  • 69
    • 84878268981 scopus 로고    scopus 로고
    • Achieving the balance between ROS and antioxidants: when to use the synthetic antioxidants
    • Poljsak, B., Šuput, D., Milisav, I., Achieving the balance between ROS and antioxidants: when to use the synthetic antioxidants. Oxid. Med. Cell. Longev., 2013, 2013, 956792.
    • (2013) Oxid. Med. Cell. Longev. , vol.2013 , pp. 956792
    • Poljsak, B.1    Šuput, D.2    Milisav, I.3
  • 70
    • 33646848795 scopus 로고    scopus 로고
    • The Mediterranean diet: science and practice
    • Willett, W.C., The Mediterranean diet: science and practice. Public Health Nutr. 9:1A (2006), 105–110.
    • (2006) Public Health Nutr. , vol.9 , Issue.1A , pp. 105-110
    • Willett, W.C.1
  • 71
    • 15544383555 scopus 로고    scopus 로고
    • The chemistry behind antioxidant capacity assays
    • Huang, D., Ou, B., Prior, R.L., The chemistry behind antioxidant capacity assays. J. Agric. Food Chem. 53:6 (2005), 1841–1856.
    • (2005) J. Agric. Food Chem. , vol.53 , Issue.6 , pp. 1841-1856
    • Huang, D.1    Ou, B.2    Prior, R.L.3
  • 72
    • 84994030074 scopus 로고    scopus 로고
    • Biological Properties of Tocotrienols: Evidence in Human Studies
    • Meganathan, P., Fu, J.Y., Biological Properties of Tocotrienols: Evidence in Human Studies. Int. J. Mol. Sci., 17(11), 2016, E1682.
    • (2016) Int. J. Mol. Sci. , vol.17 , Issue.11 , pp. E1682
    • Meganathan, P.1    Fu, J.Y.2
  • 73
    • 84953307986 scopus 로고    scopus 로고
    • Vitamin C in Health and Disease: Its Role in the Metabolism of Cells and Redox State in the Brain
    • Figueroa-Méndez, R., Rivas-Arancibia, S., Vitamin C in Health and Disease: Its Role in the Metabolism of Cells and Redox State in the Brain. Front. Physiol., 6, 2015, 397.
    • (2015) Front. Physiol. , vol.6 , pp. 397
    • Figueroa-Méndez, R.1    Rivas-Arancibia, S.2
  • 74
    • 84911479104 scopus 로고    scopus 로고
    • Oxidative stress and antioxidants in carcinogenesis and integrative therapy of cancer
    • Milkovic, L., Siems, W., Siems, R., Zarkovic, N., Oxidative stress and antioxidants in carcinogenesis and integrative therapy of cancer. Curr. Pharm. Des. 20:42 (2014), 6529–6542.
    • (2014) Curr. Pharm. Des. , vol.20 , Issue.42 , pp. 6529-6542
    • Milkovic, L.1    Siems, W.2    Siems, R.3    Zarkovic, N.4
  • 75
    • 10944242815 scopus 로고    scopus 로고
    • Apple Phenolics Protect in Vitro Oxidative Stress‐induced Neuronal Cell Death
    • Heo, H.J., Kim, D.O., Choi, S.J., Shin, D.H., Lee, C.Y., Apple Phenolics Protect in Vitro Oxidative Stress‐induced Neuronal Cell Death. J. Food Sci. 69 (2004), S357–S360.
    • (2004) J. Food Sci. , vol.69 , pp. S357-S360
    • Heo, H.J.1    Kim, D.O.2    Choi, S.J.3    Shin, D.H.4    Lee, C.Y.5
  • 76
    • 15444375546 scopus 로고    scopus 로고
    • Strawberry and its anthocyanins reduce oxidative stress-induced apoptosis in PC12 cells
    • Heo, H.J., Lee, C.Y., Strawberry and its anthocyanins reduce oxidative stress-induced apoptosis in PC12 cells. J. Agric. Food Chem. 53:6 (2005), 1984–1989.
    • (2005) J. Agric. Food Chem. , vol.53 , Issue.6 , pp. 1984-1989
    • Heo, H.J.1    Lee, C.Y.2
  • 77
    • 39749159676 scopus 로고    scopus 로고
    • Effects of banana, orange, and apple on oxidative stress-induced neurotoxicity in PC12 cells
    • Heo, H.J., Choi, S.J., Choi, S.G., Shin, D.H., Lee, J.M., Lee, C.Y., Effects of banana, orange, and apple on oxidative stress-induced neurotoxicity in PC12 cells. J. Food Sci. 73:2 (2008), H28–H32.
    • (2008) J. Food Sci. , vol.73 , Issue.2 , pp. H28-H32
    • Heo, H.J.1    Choi, S.J.2    Choi, S.G.3    Shin, D.H.4    Lee, J.M.5    Lee, C.Y.6
  • 78
    • 49649116725 scopus 로고    scopus 로고
    • Modulation of signalling nuclear factor-kappaB activation pathway by polyphenols in human intestinal Caco-2 cells
    • Romier, B., Van De Walle, J., During, A., Larondelle, Y., Schneider, Y.J., Modulation of signalling nuclear factor-kappaB activation pathway by polyphenols in human intestinal Caco-2 cells. Br. J. Nutr. 100:3 (2008), 542–551.
    • (2008) Br. J. Nutr. , vol.100 , Issue.3 , pp. 542-551
    • Romier, B.1    Van De Walle, J.2    During, A.3    Larondelle, Y.4    Schneider, Y.J.5
  • 80
    • 33744958202 scopus 로고    scopus 로고
    • Protective effect of black tea against ethanol-induced oxidative modifications of liver proteins and lipids
    • Luczaj, W., Siemieniuk, E., Roszkowska-Jakimiec, W., Skrzydlewska, E., Protective effect of black tea against ethanol-induced oxidative modifications of liver proteins and lipids. J. Stud. Alcohol. 67:4 (2006), 510–518.
    • (2006) J. Stud. Alcohol. , vol.67 , Issue.4 , pp. 510-518
    • Luczaj, W.1    Siemieniuk, E.2    Roszkowska-Jakimiec, W.3    Skrzydlewska, E.4
  • 82
    • 84922375897 scopus 로고    scopus 로고
    • Quercetin alleviates 4-hydroxynonenal-induced cytotoxicity and inflammation in ARPE-19 cells
    • Hytti, M., Piippo, N., Salminen, A., Honkakoski, P., Kaarniranta, K., Kauppinen, A., Quercetin alleviates 4-hydroxynonenal-induced cytotoxicity and inflammation in ARPE-19 cells. Exp. Eye Res. 132 (2015), 208–215.
    • (2015) Exp. Eye Res. , vol.132 , pp. 208-215
    • Hytti, M.1    Piippo, N.2    Salminen, A.3    Honkakoski, P.4    Kaarniranta, K.5    Kauppinen, A.6
  • 83
    • 14944364739 scopus 로고    scopus 로고
    • Low concentrations of flavonoids are protective in rat H4IIE cells whereas high concentrations cause DNA damage and apoptosis
    • Wätjen, W., Michels, G., Steffan, B., Niering, P., Chovolou, Y., Kampkötter, A., Tran-Thi, Q.H., Proksch, P., Kahl, R., Low concentrations of flavonoids are protective in rat H4IIE cells whereas high concentrations cause DNA damage and apoptosis. J. Nutr. 135:3 (2005), 525–531.
    • (2005) J. Nutr. , vol.135 , Issue.3 , pp. 525-531
    • Wätjen, W.1    Michels, G.2    Steffan, B.3    Niering, P.4    Chovolou, Y.5    Kampkötter, A.6    Tran-Thi, Q.H.7    Proksch, P.8    Kahl, R.9
  • 84
    • 69249214137 scopus 로고    scopus 로고
    • Quercetin can act either as an inhibitor or an inducer of the mitochondrial permeability transition pore: A demonstration of the ambivalent redox character of polyphenols
    • De Marchi, U., Biasutto, L., Garbisa, S., Toninello, A., Zoratti, M., Quercetin can act either as an inhibitor or an inducer of the mitochondrial permeability transition pore: A demonstration of the ambivalent redox character of polyphenols. Biochim. Biophys. Acta 1787:12 (2009), 1425–1432.
    • (2009) Biochim. Biophys. Acta , vol.1787 , Issue.12 , pp. 1425-1432
    • De Marchi, U.1    Biasutto, L.2    Garbisa, S.3    Toninello, A.4    Zoratti, M.5
  • 85
    • 34447096276 scopus 로고    scopus 로고
    • Antioxidative and prooxidative effects of quercetin on A549 cells
    • Robaszkiewicz, A., Balcerczyk, A., Bartosz, G., Antioxidative and prooxidative effects of quercetin on A549 cells. Cell. Biol. Int. 31:10 (2007), 1245–1250.
    • (2007) Cell. Biol. Int. , vol.31 , Issue.10 , pp. 1245-1250
    • Robaszkiewicz, A.1    Balcerczyk, A.2    Bartosz, G.3
  • 86
    • 3042574709 scopus 로고    scopus 로고
    • Potential toxicity of flavonoids and other dietary phenolics: significance for their chemopreventive and anticancer properties
    • Galati, G., O'Brien, P.J., Potential toxicity of flavonoids and other dietary phenolics: significance for their chemopreventive and anticancer properties. Free Radic. Biol. Med. 37:3 (2004), 287–303.
    • (2004) Free Radic. Biol. Med. , vol.37 , Issue.3 , pp. 287-303
    • Galati, G.1    O'Brien, P.J.2
  • 87
    • 31644435641 scopus 로고    scopus 로고
    • Cellular and in vivo hepatotoxicity caused by green tea phenolic acids and catechins
    • Galati, G., Lin, A., Sultan, A.M., O'Brien, P.J., Cellular and in vivo hepatotoxicity caused by green tea phenolic acids and catechins. Free Radic. Biol. Med. 40:4 (2006), 570–580.
    • (2006) Free Radic. Biol. Med. , vol.40 , Issue.4 , pp. 570-580
    • Galati, G.1    Lin, A.2    Sultan, A.M.3    O'Brien, P.J.4
  • 88
    • 0344806276 scopus 로고    scopus 로고
    • Prooxidant toxicity of polyphenolic antioxidants to HL-60 cells: description of quantitative structure-activity relationships
    • Sergediene, E., Jönsson, K., Szymusiak, H., Tyrakowska, B., Rietjens, I.M., Cenas, N., Prooxidant toxicity of polyphenolic antioxidants to HL-60 cells: description of quantitative structure-activity relationships. FEBS Lett. 462:3 (1999), 392–396.
    • (1999) FEBS Lett. , vol.462 , Issue.3 , pp. 392-396
    • Sergediene, E.1    Jönsson, K.2    Szymusiak, H.3    Tyrakowska, B.4    Rietjens, I.M.5    Cenas, N.6
  • 89
    • 71549144988 scopus 로고    scopus 로고
    • Lipid oxidation and peroxidation in CNS health and disease: from molecular mechanisms to therapeutic opportunities
    • Adibhatla, R.M., Hatcher, J.F., Lipid oxidation and peroxidation in CNS health and disease: from molecular mechanisms to therapeutic opportunities. Antioxid. Redox Signal. 12:1 (2010), 125–169.
    • (2010) Antioxid. Redox Signal. , vol.12 , Issue.1 , pp. 125-169
    • Adibhatla, R.M.1    Hatcher, J.F.2
  • 90
    • 3342900250 scopus 로고    scopus 로고
    • Medical progress: bipolar disorder
    • Belmaker, R.H., Medical progress: bipolar disorder. N. Engl. J. Med. 351 (2004), 476–486.
    • (2004) N. Engl. J. Med. , vol.351 , pp. 476-486
    • Belmaker, R.H.1
  • 92
    • 29044447411 scopus 로고    scopus 로고
    • Chronic treatment with mood stabilizers lithium and valproate prevents excitotoxicity by inhibiting oxidative stress in rat cerebral cortical cells
    • Shao, L., Young, L.T., Wang, J.F., Chronic treatment with mood stabilizers lithium and valproate prevents excitotoxicity by inhibiting oxidative stress in rat cerebral cortical cells. Biol. Psychiatry, 58(11), 2005, 879.
    • (2005) Biol. Psychiatry , vol.58 , Issue.11 , pp. 879
    • Shao, L.1    Young, L.T.2    Wang, J.F.3
  • 93
    • 84901398313 scopus 로고    scopus 로고
    • The neurobiology of bipolar disorder: identifying targets for specific agents and synergies for combination treatment
    • Andreazza, A.C., Young, L.T., The neurobiology of bipolar disorder: identifying targets for specific agents and synergies for combination treatment. Int. J. Neuropsychopharmacol. 17:7 (2014), 1039–1052.
    • (2014) Int. J. Neuropsychopharmacol. , vol.17 , Issue.7 , pp. 1039-1052
    • Andreazza, A.C.1    Young, L.T.2
  • 94
    • 81955161265 scopus 로고    scopus 로고
    • Mitochondria, oligodendrocytes and inflammation in bipolar disorder: evidence from transcriptome studies points to intriguing parallels with multiple sclerosis
    • Konradi, C., Sillivan, S.E., Clay, H.B., Mitochondria, oligodendrocytes and inflammation in bipolar disorder: evidence from transcriptome studies points to intriguing parallels with multiple sclerosis. Neurobiol. Dis. 45:1 (2012), 37–47.
    • (2012) Neurobiol. Dis. , vol.45 , Issue.1 , pp. 37-47
    • Konradi, C.1    Sillivan, S.E.2    Clay, H.B.3
  • 96
    • 67749122382 scopus 로고    scopus 로고
    • Increased oxidative stress in the anterior cingulate cortex of subjects with bipolar disorder and schizophrenia
    • Wang, J.F., Shao, L., Sun, X., Young, L.T., Increased oxidative stress in the anterior cingulate cortex of subjects with bipolar disorder and schizophrenia. Bipolar Disord. 11:5 (2009), 523–529.
    • (2009) Bipolar Disord. , vol.11 , Issue.5 , pp. 523-529
    • Wang, J.F.1    Shao, L.2    Sun, X.3    Young, L.T.4
  • 97
    • 0034986909 scopus 로고    scopus 로고
    • The anterior cingulated cortex. The evolution of an interface between emotion and cognition
    • Allman, J.M., Hakeem, A., Erwin, J.M., Nimchinsky, E., Hof, P., The anterior cingulated cortex. The evolution of an interface between emotion and cognition. Ann. N. Y. Acad. Sci. 935 (2001), 107–117.
    • (2001) Ann. N. Y. Acad. Sci. , vol.935 , pp. 107-117
    • Allman, J.M.1    Hakeem, A.2    Erwin, J.M.3    Nimchinsky, E.4    Hof, P.5
  • 99
    • 84902087370 scopus 로고    scopus 로고
    • An updated meta-analysis of oxidative stress markers in bipolar disorder
    • Brown, N.C., Andreazza, A.C., Young, L.T., An updated meta-analysis of oxidative stress markers in bipolar disorder. Psychiatry Res. 218:1–2 (2014), 61–68.
    • (2014) Psychiatry Res. , vol.218 , Issue.1-2 , pp. 61-68
    • Brown, N.C.1    Andreazza, A.C.2    Young, L.T.3
  • 102
    • 84871520685 scopus 로고    scopus 로고
    • Mood stabilizer lithium inhibits amphetamine-increased 4-hydroxynonenal-protein adducts in rat frontal cortex
    • Tan, H., Young, L.T., Shao, L., Che, Y., Honer, W.G., Wang, J.F., Mood stabilizer lithium inhibits amphetamine-increased 4-hydroxynonenal-protein adducts in rat frontal cortex. Int. J. Neuropsychopharmacol. 15:9 (2012), 1275–1285.
    • (2012) Int. J. Neuropsychopharmacol. , vol.15 , Issue.9 , pp. 1275-1285
    • Tan, H.1    Young, L.T.2    Shao, L.3    Che, Y.4    Honer, W.G.5    Wang, J.F.6
  • 103
    • 42049087464 scopus 로고    scopus 로고
    • Norepinephrine and serotonin imbalance in the locus coeruleus in bipolar disorder
    • Wiste, A.K., Arango, V., Ellis, S.P., Mann, J.J., Underwood, M.D., Norepinephrine and serotonin imbalance in the locus coeruleus in bipolar disorder. Bipolar Disord. 10:3 (2008), 349–359.
    • (2008) Bipolar Disord. , vol.10 , Issue.3 , pp. 349-359
    • Wiste, A.K.1    Arango, V.2    Ellis, S.P.3    Mann, J.J.4    Underwood, M.D.5
  • 104
    • 71049173312 scopus 로고    scopus 로고
    • The role of dopamine in bipolar disorder
    • Cousins, D.A., Butts, K., Young, A.H., The role of dopamine in bipolar disorder. Bipolar Disord. 11:8 (2009), 787–806.
    • (2009) Bipolar Disord. , vol.11 , Issue.8 , pp. 787-806
    • Cousins, D.A.1    Butts, K.2    Young, A.H.3
  • 105
    • 84858339654 scopus 로고    scopus 로고
    • Altered serotonergic function may partially account for behavioral endophenotypes in steroid sulfatase-deficient mice
    • Trent, S., Cassano, T., Bedse, G., Ojarikre, O.A., Humby, T., Davies, W., Altered serotonergic function may partially account for behavioral endophenotypes in steroid sulfatase-deficient mice. Neuropsychopharmacology 37:5 (2012), 1267–1274.
    • (2012) Neuropsychopharmacology , vol.37 , Issue.5 , pp. 1267-1274
    • Trent, S.1    Cassano, T.2    Bedse, G.3    Ojarikre, O.A.4    Humby, T.5    Davies, W.6
  • 106
    • 84878657803 scopus 로고    scopus 로고
    • Biological mechanisms associated with increased perseveration and hyperactivity in a genetic mouse model of neurodevelopmental disorder
    • Trent, S., Dean, R., Veit, B., Cassano, T., Bedse, G., Ojarikre, O.A., Humby, T., Davies, W., Biological mechanisms associated with increased perseveration and hyperactivity in a genetic mouse model of neurodevelopmental disorder. Psychoneuroendocrinology 38:8 (2013), 1370–1380.
    • (2013) Psychoneuroendocrinology , vol.38 , Issue.8 , pp. 1370-1380
    • Trent, S.1    Dean, R.2    Veit, B.3    Cassano, T.4    Bedse, G.5    Ojarikre, O.A.6    Humby, T.7    Davies, W.8
  • 107
    • 0036212608 scopus 로고    scopus 로고
    • Role of the cholinergic muscarinic system in bipolar disorder and related mechanism of action of antipsychotic agents
    • Bymaster, F.P., Felder, C.C., Role of the cholinergic muscarinic system in bipolar disorder and related mechanism of action of antipsychotic agents. Mol. Psychiatry 1 (2002), S57–S63.
    • (2002) Mol. Psychiatry , vol.1 , pp. S57-S63
    • Bymaster, F.P.1    Felder, C.C.2
  • 108
    • 0036382921 scopus 로고    scopus 로고
    • Dopamine D4 receptor and tyrosine hydroxylase genes in bipolar disorder: evidence for a role of DRD4
    • Muglia, P., Petronis, A., Mundo, E., Lander, S., Cate, T., Kennedy, J.L., Dopamine D4 receptor and tyrosine hydroxylase genes in bipolar disorder: evidence for a role of DRD4. Mol. Psychiatry 7:8 (2002), 860–866.
    • (2002) Mol. Psychiatry , vol.7 , Issue.8 , pp. 860-866
    • Muglia, P.1    Petronis, A.2    Mundo, E.3    Lander, S.4    Cate, T.5    Kennedy, J.L.6
  • 109
    • 27444434056 scopus 로고    scopus 로고
    • Beyond monoamines: glutamatergic function in mood disorders
    • Kugaya, A., Sanacora, G., Beyond monoamines: glutamatergic function in mood disorders. CNS Spectr. 10:10 (2005), 808–819.
    • (2005) CNS Spectr. , vol.10 , Issue.10 , pp. 808-819
    • Kugaya, A.1    Sanacora, G.2
  • 110
    • 0030836707 scopus 로고    scopus 로고
    • 4-Hydroxynonenal, an aldehydic product of lipid peroxidation, impairs signal transduction associated with muscarinic acetylcholine and metabotropic glutamate receptors: possible action on G alpha (q/11)
    • Blanc, E.M., Kelly, J.F., Mark, R.J., Waeg, G., Mattson, M.P., 4-Hydroxynonenal, an aldehydic product of lipid peroxidation, impairs signal transduction associated with muscarinic acetylcholine and metabotropic glutamate receptors: possible action on G alpha (q/11). J. Neurochem. 69:2 (1997), 570–580.
    • (1997) J. Neurochem. , vol.69 , Issue.2 , pp. 570-580
    • Blanc, E.M.1    Kelly, J.F.2    Mark, R.J.3    Waeg, G.4    Mattson, M.P.5
  • 111
    • 0035691024 scopus 로고    scopus 로고
    • Depression as a spreading adjustment disorder of monoaminergic neurons: a case for primary implication of the locus coeruleus
    • Harro, J., Oreland, L., Depression as a spreading adjustment disorder of monoaminergic neurons: a case for primary implication of the locus coeruleus. Brain Res. 38:1–2 (2001), 79–128.
    • (2001) Brain Res. , vol.38 , Issue.1-2 , pp. 79-128
    • Harro, J.1    Oreland, L.2
  • 113
    • 79954578338 scopus 로고    scopus 로고
    • Beyond the serotonin hypothesis: mitochondria, inflammation and neurodegeneration in major depression and affective spectrum disorders
    • Gardner, A., Boles, R.G., Beyond the serotonin hypothesis: mitochondria, inflammation and neurodegeneration in major depression and affective spectrum disorders. Prog. Neuropsychopharmacol. Biol. Psychiatry 35:3 (2011), 730–743.
    • (2011) Prog. Neuropsychopharmacol. Biol. Psychiatry , vol.35 , Issue.3 , pp. 730-743
    • Gardner, A.1    Boles, R.G.2
  • 114
    • 84876952909 scopus 로고    scopus 로고
    • Mitochondrial dysfunction, oxidative stress, and major depressive disorder
    • Tobe, E.H., Mitochondrial dysfunction, oxidative stress, and major depressive disorder. Neuropsychiatr. Dis. Treat. 9 (2013), 567–573.
    • (2013) Neuropsychiatr. Dis. Treat. , vol.9 , pp. 567-573
    • Tobe, E.H.1
  • 115
    • 0042967431 scopus 로고    scopus 로고
    • Alterations of mitochondrial function and correlations with personality traits in selected major depressive disorder patients
    • Gardner, A., Johansson, A., Wibom, R., Nennesmo, I., von Döbeln, U., Hagenfeldt, L., Hällström, T., Alterations of mitochondrial function and correlations with personality traits in selected major depressive disorder patients. J. Affect. Disord. 76:1–3 (2003), 55–68.
    • (2003) J. Affect. Disord. , vol.76 , Issue.1-3 , pp. 55-68
    • Gardner, A.1    Johansson, A.2    Wibom, R.3    Nennesmo, I.4    von Döbeln, U.5    Hagenfeldt, L.6    Hällström, T.7
  • 117
    • 2342530936 scopus 로고    scopus 로고
    • Increased (E)-4-hydroxy-2-nonenal and asymmetric dimethylarginine concentrations and decreased nitric oxide concentrations in the plasma of patients with major depression
    • Selley, M.L., Increased (E)-4-hydroxy-2-nonenal and asymmetric dimethylarginine concentrations and decreased nitric oxide concentrations in the plasma of patients with major depression. J. Affect. Disord. 80:2–3 (2004), 249–256.
    • (2004) J. Affect. Disord. , vol.80 , Issue.2-3 , pp. 249-256
    • Selley, M.L.1
  • 118
    • 0033282727 scopus 로고    scopus 로고
    • Major depression and activation of the inflammatory response system
    • Maes, M., Major depression and activation of the inflammatory response system. Adv. Exp. Med. Biol. 461 (1999), 25–46.
    • (1999) Adv. Exp. Med. Biol. , vol.461 , pp. 25-46
    • Maes, M.1
  • 119
    • 0034106884 scopus 로고    scopus 로고
    • Lower serum vitamin E concentrations in major depression. Another marker of lowered antioxidant defenses in that illness
    • Maes, M., De Vos, N., Pioli, R., Demedts, P., Wauters, A., Neels, H., Christophe, A., Lower serum vitamin E concentrations in major depression. Another marker of lowered antioxidant defenses in that illness. J. Affect. Disord. 58:3 (2000), 241–246.
    • (2000) J. Affect. Disord. , vol.58 , Issue.3 , pp. 241-246
    • Maes, M.1    De Vos, N.2    Pioli, R.3    Demedts, P.4    Wauters, A.5    Neels, H.6    Christophe, A.7
  • 120
    • 0035065919 scopus 로고    scopus 로고
    • Antioxidative enzyme activities and lipid peroxidation in major depression: alterations by antidepressant treatments
    • Bilici, M., Efe, H., Köroğlu, M.A., Uydu, H.A., Bekaroğlu, M., Değer, O., Antioxidative enzyme activities and lipid peroxidation in major depression: alterations by antidepressant treatments. J. Affect. Disord. 64:1 (2001), 43–51.
    • (2001) J. Affect. Disord. , vol.64 , Issue.1 , pp. 43-51
    • Bilici, M.1    Efe, H.2    Köroğlu, M.A.3    Uydu, H.A.4    Bekaroğlu, M.5    Değer, O.6
  • 122
    • 0033765902 scopus 로고    scopus 로고
    • Novel neurotransmitters and their neuropsychiatric relevance
    • Snyder, S.H., Ferris, C.D., Novel neurotransmitters and their neuropsychiatric relevance. Am. J. Psychiatry 157:11 (2000), 1738–1751.
    • (2000) Am. J. Psychiatry , vol.157 , Issue.11 , pp. 1738-1751
    • Snyder, S.H.1    Ferris, C.D.2
  • 123
    • 0034281379 scopus 로고    scopus 로고
    • Superior water maze performance and increase in fear-related behavior in the endothelial nitric oxide synthase-deficient mouse together with monoamine changes in cerebellum and ventral striatum
    • Frisch, C., Dere, E., Silva, M.A., Godecke, A., Schrader, J., Huston, J.P., Superior water maze performance and increase in fear-related behavior in the endothelial nitric oxide synthase-deficient mouse together with monoamine changes in cerebellum and ventral striatum. J. Neurosci. 20:17 (2000), 6694–6700.
    • (2000) J. Neurosci. , vol.20 , Issue.17 , pp. 6694-6700
    • Frisch, C.1    Dere, E.2    Silva, M.A.3    Godecke, A.4    Schrader, J.5    Huston, J.P.6
  • 125
    • 84939477733 scopus 로고    scopus 로고
    • The impact of mitochondrial aldehyde dehydrogenase (ALDH2) activation by Alda-1 on the behavioral and biochemical disturbances in animal model of depression
    • Stachowicz, A., Głombik, K., Olszanecki, R., Basta-Kaim, A., Suski, M., Lasoń, W., Korbut, R., The impact of mitochondrial aldehyde dehydrogenase (ALDH2) activation by Alda-1 on the behavioral and biochemical disturbances in animal model of depression. Brain Behav. Immun. 51 (2016), 144–153.
    • (2016) Brain Behav. Immun. , vol.51 , pp. 144-153
    • Stachowicz, A.1    Głombik, K.2    Olszanecki, R.3    Basta-Kaim, A.4    Suski, M.5    Lasoń, W.6    Korbut, R.7
  • 126
    • 84891551821 scopus 로고    scopus 로고
    • Targeting aldehyde dehydrogenase 2: new therapeutic opportunities
    • Chen, C.H., Ferreira, J.C., Gross, E.R., Mochly-Rosen, D., Targeting aldehyde dehydrogenase 2: new therapeutic opportunities. Physiol. Rev. 94:1 (2014), 1–34.
    • (2014) Physiol. Rev. , vol.94 , Issue.1 , pp. 1-34
    • Chen, C.H.1    Ferreira, J.C.2    Gross, E.R.3    Mochly-Rosen, D.4
  • 127
    • 0029863799 scopus 로고    scopus 로고
    • Kinetics and specificity of human liver aldehyde dehydrogenases toward aliphatic, aromatic, and fused polycyclic aldehydes
    • Klyosov, A.A., Kinetics and specificity of human liver aldehyde dehydrogenases toward aliphatic, aromatic, and fused polycyclic aldehydes. Biochemistry 35 (1996), 4457–4467.
    • (1996) Biochemistry , vol.35 , pp. 4457-4467
    • Klyosov, A.A.1
  • 128
    • 77956565655 scopus 로고    scopus 로고
    • Mitochondrial aldehyde dehydrogenase and cardiac diseases
    • Chen, C.H., Sun, L., Mochly-Rosen, D., Mitochondrial aldehyde dehydrogenase and cardiac diseases. Cardiovasc. Res. 88:1 (2010), 51–57.
    • (2010) Cardiovasc. Res. , vol.88 , Issue.1 , pp. 51-57
    • Chen, C.H.1    Sun, L.2    Mochly-Rosen, D.3
  • 129
    • 84858675338 scopus 로고    scopus 로고
    • Differences in susceptibility to inactivation of human aldehyde dehydrogenases by lipid peroxidation byproducts
    • Yoval-Sanchez, B., Rodriguez-Zavala, J.S., Differences in susceptibility to inactivation of human aldehyde dehydrogenases by lipid peroxidation byproducts. Chem. Res. Toxicol. 25 (2012), 722–729.
    • (2012) Chem. Res. Toxicol. , vol.25 , pp. 722-729
    • Yoval-Sanchez, B.1    Rodriguez-Zavala, J.S.2
  • 130
    • 0030077380 scopus 로고    scopus 로고
    • Distribution of messenger RNAs for aldehyde dehydrogenase 1, aldehyde dehydrogenase 2, and aldehyde dehydrogenase 5 in human tissues
    • Stewart, M.J., Malek, K., Crabb, D.W., Distribution of messenger RNAs for aldehyde dehydrogenase 1, aldehyde dehydrogenase 2, and aldehyde dehydrogenase 5 in human tissues. J. Investig. Med. 44 (1996), 42–46.
    • (1996) J. Investig. Med. , vol.44 , pp. 42-46
    • Stewart, M.J.1    Malek, K.2    Crabb, D.W.3
  • 131
    • 21344448749 scopus 로고    scopus 로고
    • Tissue-distribution of aldehyde dehydrogenase 2 and effects of the ALDH2 gene-disruption on the expression of enzymes involved in alcohol metabolism
    • Oyama, T., Isse, T., Kagawa, N., Kinaga, T., Kim, Y.D., Morita, M., Sugio, K., Weiner, H., Yasumoto, K., Kawamoto, T., Tissue-distribution of aldehyde dehydrogenase 2 and effects of the ALDH2 gene-disruption on the expression of enzymes involved in alcohol metabolism. Front. Biosci. 10 (2005), 951–960.
    • (2005) Front. Biosci. , vol.10 , pp. 951-960
    • Oyama, T.1    Isse, T.2    Kagawa, N.3    Kinaga, T.4    Kim, Y.D.5    Morita, M.6    Sugio, K.7    Weiner, H.8    Yasumoto, K.9    Kawamoto, T.10
  • 132
    • 76349110761 scopus 로고    scopus 로고
    • Alda-1 is an agonist and chemical chaperone for the common human aldehyde dehydrogenase 2 variant
    • Perez-Miller, S., Younus, H., Vanam, R., Chen, C.H., Mochly-Rosen, D., Hurley, T.D., Alda-1 is an agonist and chemical chaperone for the common human aldehyde dehydrogenase 2 variant. Nat. Struct. Mol. Biol. 17:2 (2010), 159–164.
    • (2010) Nat. Struct. Mol. Biol. , vol.17 , Issue.2 , pp. 159-164
    • Perez-Miller, S.1    Younus, H.2    Vanam, R.3    Chen, C.H.4    Mochly-Rosen, D.5    Hurley, T.D.6
  • 133
    • 83255193365 scopus 로고    scopus 로고
    • Maternal docosahexaenoic acid feeding protects against impairment of learning and memory and oxidative stress in prenatally stressed rats: possible role of neuronal mitochondria metabolism
    • Feng, Z., Zou, X., Jia, H., Li, X., Zhu, Z., Liu, X., Bucheli, P., Ballevre, O., Hou, Y., Zhang, W., Wang, J., Chen, Y., Liu, J., Maternal docosahexaenoic acid feeding protects against impairment of learning and memory and oxidative stress in prenatally stressed rats: possible role of neuronal mitochondria metabolism. Antioxid. Redox Signal. 16:3 (2012), 275–289.
    • (2012) Antioxid. Redox Signal. , vol.16 , Issue.3 , pp. 275-289
    • Feng, Z.1    Zou, X.2    Jia, H.3    Li, X.4    Zhu, Z.5    Liu, X.6    Bucheli, P.7    Ballevre, O.8    Hou, Y.9    Zhang, W.10    Wang, J.11    Chen, Y.12    Liu, J.13
  • 134
    • 85022152027 scopus 로고    scopus 로고
    • American Psychiatric Association, Diagnostic and statistical manual of mental disorders, 5th ed., Washington, DC.
    • American Psychiatric Association, Diagnostic and statistical manual of mental disorders, 5th ed., 2013, Washington, DC.
    • (2013)
  • 135
    • 84897116431 scopus 로고
    • Oxygen metabolism in schizophrenia
    • Hoskins, R.G., Oxygen metabolism in schizophrenia. Arch. Neurol. Psychiatry 38:6 (1937), 1261–1270.
    • (1937) Arch. Neurol. Psychiatry , vol.38 , Issue.6 , pp. 1261-1270
    • Hoskins, R.G.1
  • 137
    • 84897113069 scopus 로고    scopus 로고
    • Oxidative stress and schizophrenia: recent breakthroughs from an old story
    • Emiliani, F.E., Sedlak, T.W., Sawa, A., Oxidative stress and schizophrenia: recent breakthroughs from an old story. Curr. Opin. Psychiatry 27:3 (2014), 185–190.
    • (2014) Curr. Opin. Psychiatry , vol.27 , Issue.3 , pp. 185-190
    • Emiliani, F.E.1    Sedlak, T.W.2    Sawa, A.3
  • 139
    • 0037411282 scopus 로고    scopus 로고
    • 4-Hydroxy-2-nonenal: a product and mediator of oxidative stress
    • Uchida, K., 4-Hydroxy-2-nonenal: a product and mediator of oxidative stress. Prog. Lipid Res. 42:4 (2003), 318–343.
    • (2003) Prog. Lipid Res. , vol.42 , Issue.4 , pp. 318-343
    • Uchida, K.1
  • 140
    • 2942572700 scopus 로고    scopus 로고
    • Measuring reactive species and oxidative damage in vivo and in cell culture: how should you do it and what do the results mean?
    • Halliwell, B., Whiteman, M., Measuring reactive species and oxidative damage in vivo and in cell culture: how should you do it and what do the results mean?. Br. J. Pharmacol. 142:2 (2004), 231–255.
    • (2004) Br. J. Pharmacol. , vol.142 , Issue.2 , pp. 231-255
    • Halliwell, B.1    Whiteman, M.2
  • 142
    • 0036571065 scopus 로고    scopus 로고
    • Cognitive deficits, schizophrenia, and the anterior cingulate cortex
    • Sanders, G.S., Gallup, G.G., Heinsen, H., Hof, P.R., Schmitz, C., Cognitive deficits, schizophrenia, and the anterior cingulate cortex. Trends Cogn. Sci. 6:5 (2002), 190–192.
    • (2002) Trends Cogn. Sci. , vol.6 , Issue.5 , pp. 190-192
    • Sanders, G.S.1    Gallup, G.G.2    Heinsen, H.3    Hof, P.R.4    Schmitz, C.5
  • 143
    • 69249157220 scopus 로고    scopus 로고
    • Anatomical abnormalities of the anterior cingulate cortex in schizophrenia: bridging the gap between neuroimaging and neuropathology
    • Fornito, A., Yücel, M., Dean, B., Wood, S.J., Pantelis, C., Anatomical abnormalities of the anterior cingulate cortex in schizophrenia: bridging the gap between neuroimaging and neuropathology. Schizophr. Bull. 35:5 (2009), 973–993.
    • (2009) Schizophr. Bull. , vol.35 , Issue.5 , pp. 973-993
    • Fornito, A.1    Yücel, M.2    Dean, B.3    Wood, S.J.4    Pantelis, C.5
  • 145
    • 0043173819 scopus 로고    scopus 로고
    • Olanzapine protects PC12 cells from oxidative stress induced by hydrogen peroxide
    • Wei, Z., Bai, O., Richardson, J.S., Mousseau, D.D., Li, X.M., Olanzapine protects PC12 cells from oxidative stress induced by hydrogen peroxide. J. Neurosci. Res. 73:3 (2003), 364–368.
    • (2003) J. Neurosci. Res. , vol.73 , Issue.3 , pp. 364-368
    • Wei, Z.1    Bai, O.2    Richardson, J.S.3    Mousseau, D.D.4    Li, X.M.5
  • 146
    • 33846847640 scopus 로고    scopus 로고
    • Long-term antipsychotic treatments and crossover studies in rats: differential effects of typical and atypical agents on the expression of antioxidant enzymes and membrane lipid peroxidation in rat brain
    • Pillai, A., Parikh, V., Terry, A.V., Jr, Mahadik, S.P., Long-term antipsychotic treatments and crossover studies in rats: differential effects of typical and atypical agents on the expression of antioxidant enzymes and membrane lipid peroxidation in rat brain. J. Psychiatr. Res. 41:5 (2007), 372–386.
    • (2007) J. Psychiatr. Res. , vol.41 , Issue.5 , pp. 372-386
    • Pillai, A.1    Parikh, V.2    Terry, A.V.3    Mahadik, S.P.4
  • 149
    • 0028925115 scopus 로고
    • Definition of therapy-resistant schizophrenia and its assessment
    • Brenner, H., Merlo, M., Definition of therapy-resistant schizophrenia and its assessment. Eur. Psychiatry 10:Suppl. 1 (1995), S11–S17.
    • (1995) Eur. Psychiatry , vol.10 , pp. S11-S17
    • Brenner, H.1    Merlo, M.2
  • 151
    • 0035711934 scopus 로고    scopus 로고
    • Impairments in attention and facial emotion recognition in treatment of refractory and non refractory schizophrenics evaluated through an odd-ball paradigm
    • Ramos, J., Cerdán, L.F., Guevara, M.A., Amezcua, C., Impairments in attention and facial emotion recognition in treatment of refractory and non refractory schizophrenics evaluated through an odd-ball paradigm. Rev. Neurol. 33:11 (2001), 1027–1032.
    • (2001) Rev. Neurol. , vol.33 , Issue.11 , pp. 1027-1032
    • Ramos, J.1    Cerdán, L.F.2    Guevara, M.A.3    Amezcua, C.4
  • 152
    • 0037376596 scopus 로고    scopus 로고
    • Hormonal aspects of schizophrenias: an overview
    • Halbreich, U., Kahn, L.S., Hormonal aspects of schizophrenias: an overview. Psychoneuroendocrinology 28:Suppl. 2 (2003), S1–S16.
    • (2003) Psychoneuroendocrinology , vol.28 , pp. S1-S16
    • Halbreich, U.1    Kahn, L.S.2
  • 154
    • 0037377075 scopus 로고    scopus 로고
    • Effects of estrogen on brain development and neuroprotection–implications for negative symptoms in schizophrenia
    • Rao, M.L., Kölsch, H., Effects of estrogen on brain development and neuroprotection–implications for negative symptoms in schizophrenia. Psychoneuroendocrinology 28:Suppl. 2 (2003), S83–S96.
    • (2003) Psychoneuroendocrinology , vol.28 , pp. S83-S96
    • Rao, M.L.1    Kölsch, H.2
  • 155
    • 77951244100 scopus 로고    scopus 로고
    • Omega-3 fatty acids and cognitive function in women
    • Robinson, J.G., Ijioma, N., Harris, W., Omega-3 fatty acids and cognitive function in women. Women's Health 6:1 (2010), 119–134.
    • (2010) Women's Health , vol.6 , Issue.1 , pp. 119-134
    • Robinson, J.G.1    Ijioma, N.2    Harris, W.3
  • 156
    • 84899154969 scopus 로고    scopus 로고
    • Mood disorders in Huntington's disease: from behavior to cellular and molecular mechanisms
    • Pla, P., Orvoen, S., Saudou, F., David, D.J., Humbert, S., Mood disorders in Huntington's disease: from behavior to cellular and molecular mechanisms. Front. Behav. Neurosci., 8, 2014, 135.
    • (2014) Front. Behav. Neurosci. , vol.8 , pp. 135
    • Pla, P.1    Orvoen, S.2    Saudou, F.3    David, D.J.4    Humbert, S.5
  • 157
    • 68849083063 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor in neurodegenerative diseases
    • Zuccato, C., Cattaneo, E., Brain-derived neurotrophic factor in neurodegenerative diseases. Nat. Rev. Neurol. 5:6 (2009), 311–322.
    • (2009) Nat. Rev. Neurol. , vol.5 , Issue.6 , pp. 311-322
    • Zuccato, C.1    Cattaneo, E.2
  • 158
    • 84906096688 scopus 로고    scopus 로고
    • Therapeutic Approaches for Inhibition of Protein Aggregation in Huntington's Disease
    • Kim, S., Kim, K.T., Therapeutic Approaches for Inhibition of Protein Aggregation in Huntington's Disease. Exp. Neurobiol. 23:1 (2014), 36–44.
    • (2014) Exp. Neurobiol. , vol.23 , Issue.1 , pp. 36-44
    • Kim, S.1    Kim, K.T.2
  • 160
    • 84884904263 scopus 로고    scopus 로고
    • PGC-1α, mitochondrial dysfunction, and Huntington's disease
    • Johri, A., Chandra, A., Beal, M.F., PGC-1α, mitochondrial dysfunction, and Huntington's disease. Free Radic. Biol. Med. 62 (2013), 37–46.
    • (2013) Free Radic. Biol. Med. , vol.62 , pp. 37-46
    • Johri, A.1    Chandra, A.2    Beal, M.F.3
  • 161
    • 79954575043 scopus 로고    scopus 로고
    • Modulation of lipid peroxidation and mitochondrial function improves neuropathology in Huntington's disease mice
    • Lee, J., Kosaras, B., Del Signore, S.J., Cormier, K., McKee, A., Ratan, R.R., Kowall, N.W., Ryu, H., Modulation of lipid peroxidation and mitochondrial function improves neuropathology in Huntington's disease mice. Acta Neuropathol. 121:4 (2011), 487–498.
    • (2011) Acta Neuropathol. , vol.121 , Issue.4 , pp. 487-498
    • Lee, J.1    Kosaras, B.2    Del Signore, S.J.3    Cormier, K.4    McKee, A.5    Ratan, R.R.6    Kowall, N.W.7    Ryu, H.8
  • 162
    • 0020487253 scopus 로고
    • Causes of death in Huntington's disease
    • Chiu, E., Alexander, L., Causes of death in Huntington's disease. Med. J. Aust., 1(4), 1982, 153.
    • (1982) Med. J. Aust. , vol.1 , Issue.4 , pp. 153
    • Chiu, E.1    Alexander, L.2
  • 163
    • 0023941141 scopus 로고
    • Huntington's disease mortality in the United States
    • Lanska, D.J., Lavine, L., Lanska, M.J., Schoenberg, B.S., Huntington's disease mortality in the United States. Neurology 38:5 (1988), 769–772.
    • (1988) Neurology , vol.38 , Issue.5 , pp. 769-772
    • Lanska, D.J.1    Lavine, L.2    Lanska, M.J.3    Schoenberg, B.S.4
  • 164
    • 0027078587 scopus 로고
    • Causes of death in patients with Huntington's disease and in unaffected first degree relatives
    • Sorensen, S.A., Fenger, K., Causes of death in patients with Huntington's disease and in unaffected first degree relatives. J. Med. Genet. 29:12 (1992), 911–914.
    • (1992) J. Med. Genet. , vol.29 , Issue.12 , pp. 911-914
    • Sorensen, S.A.1    Fenger, K.2
  • 165
    • 84937721207 scopus 로고    scopus 로고
    • Oral treatment with herbal formula B307 alleviates cardiac failure in aging R6/2 mice with Huntington's disease via suppressing oxidative stress, inflammation, and apoptosis
    • Lin, C.L., Wang, S.E., Hsu, C.H., Sheu, S.J., Wu, C.H., Oral treatment with herbal formula B307 alleviates cardiac failure in aging R6/2 mice with Huntington's disease via suppressing oxidative stress, inflammation, and apoptosis. Clin. Interv. Aging 10 (2015), 1173–1187.
    • (2015) Clin. Interv. Aging , vol.10 , pp. 1173-1187
    • Lin, C.L.1    Wang, S.E.2    Hsu, C.H.3    Sheu, S.J.4    Wu, C.H.5
  • 168
    • 0038727936 scopus 로고    scopus 로고
    • Description of Parkinson's disease as a clinical syndrome
    • Fahn, S., Description of Parkinson's disease as a clinical syndrome. Ann. N. Y. Acad. Sci. 991 (2003), 1–14.
    • (2003) Ann. N. Y. Acad. Sci. , vol.991 , pp. 1-14
    • Fahn, S.1
  • 169
    • 48349148611 scopus 로고    scopus 로고
    • Nonmotor symptoms in Parkinson's disease: investigating early-phase onset of behavioral dysfunction in the 6-hydroxydopamine-lesioned rat model
    • Branchi, I., D'Andrea, I., Armida, M., Cassano, T., Pèzzola, A., Potenza, R.L., Morgese, M.G., Popoli, P., Alleva, E., Nonmotor symptoms in Parkinson's disease: investigating early-phase onset of behavioral dysfunction in the 6-hydroxydopamine-lesioned rat model. J. Neurosci. Res. 86:9 (2008), 2050–2061.
    • (2008) J. Neurosci. Res. , vol.86 , Issue.9 , pp. 2050-2061
    • Branchi, I.1    D'Andrea, I.2    Armida, M.3    Cassano, T.4    Pèzzola, A.5    Potenza, R.L.6    Morgese, M.G.7    Popoli, P.8    Alleva, E.9
  • 172
    • 84995592220 scopus 로고    scopus 로고
    • An overview on the role of α-synuclein inexperimental models of Parkinson's disease from pathogenesis to therapeutics
    • Javed, H., Kamal, M.A., Ojha, S., An overview on the role of α-synuclein inexperimental models of Parkinson's disease from pathogenesis to therapeutics. CNS Neurol. Disord. Drug Targets, 2016.
    • (2016) CNS Neurol. Disord. Drug Targets
    • Javed, H.1    Kamal, M.A.2    Ojha, S.3
  • 173
    • 84996111069 scopus 로고
    • Is Parkinson's disease a progressive siderosis of substantia nigra resulting in iron and melanin induced neurodegeneration?
    • Youdim, M.B., Ben-Shachar, D., Riederer, P., Is Parkinson's disease a progressive siderosis of substantia nigra resulting in iron and melanin induced neurodegeneration?. Acta Neurol. Scand. Suppl. 126 (1989), 47–54.
    • (1989) Acta Neurol. Scand. Suppl. , vol.126 , pp. 47-54
    • Youdim, M.B.1    Ben-Shachar, D.2    Riederer, P.3
  • 174
    • 0026337175 scopus 로고
    • Oxidative stress as a cause of Parkinson's disease
    • Jenner, P., Oxidative stress as a cause of Parkinson's disease. Acta Neurol. Scand. Suppl. 136 (1991), 6–15.
    • (1991) Acta Neurol. Scand. Suppl. , vol.136 , pp. 6-15
    • Jenner, P.1
  • 175
    • 0026740057 scopus 로고
    • New insights into the cause of Parkinson's disease
    • Jenner, P., Schapira, A.H., Marsden, C.D., New insights into the cause of Parkinson's disease. Neurology 42:12 (1992), 2241–2250.
    • (1992) Neurology , vol.42 , Issue.12 , pp. 2241-2250
    • Jenner, P.1    Schapira, A.H.2    Marsden, C.D.3
  • 176
    • 0026754574 scopus 로고
    • Reactive oxygen species and the central nervous system
    • Halliwell, B., Reactive oxygen species and the central nervous system. J. Neurochem. 59:5 (1992), 1609–1623.
    • (1992) J. Neurochem. , vol.59 , Issue.5 , pp. 1609-1623
    • Halliwell, B.1
  • 177
    • 0028059308 scopus 로고
    • Oxidative damage in neurodegenerative disease
    • Jenner, P., Oxidative damage in neurodegenerative disease. Lancet 344:8925 (1994), 796–798.
    • (1994) Lancet , vol.344 , Issue.8925 , pp. 796-798
    • Jenner, P.1
  • 178
    • 0032936755 scopus 로고    scopus 로고
    • Etiology and pathogenesis of Parkinson's disease
    • Olanow, C.W., Tatton, W.G., Etiology and pathogenesis of Parkinson's disease. Annu. Rev. Neurosci. 22 (1999), 123–144.
    • (1999) Annu. Rev. Neurosci. , vol.22 , pp. 123-144
    • Olanow, C.W.1    Tatton, W.G.2
  • 179
    • 77955366745 scopus 로고    scopus 로고
    • Role of post-translational modifications in modulating the structure, function and toxicity of alpha-synuclein: implications for Parkinson's disease pathogenesis and therapies
    • Oueslati, A., Fournier, M., Lashuel, H.A., Role of post-translational modifications in modulating the structure, function and toxicity of alpha-synuclein: implications for Parkinson's disease pathogenesis and therapies. Prog. Brain Res. 183 (2010), 115–145.
    • (2010) Prog. Brain Res. , vol.183 , pp. 115-145
    • Oueslati, A.1    Fournier, M.2    Lashuel, H.A.3
  • 180
    • 77956389018 scopus 로고    scopus 로고
    • Evaluation of nonenzymatic posttranslational modification-derived products as biomarkers of molecular aging of proteins
    • Jaisson, S., Gillery, P., Evaluation of nonenzymatic posttranslational modification-derived products as biomarkers of molecular aging of proteins. Clin. Chem. 56:9 (2010), 1401–1412.
    • (2010) Clin. Chem. , vol.56 , Issue.9 , pp. 1401-1412
    • Jaisson, S.1    Gillery, P.2
  • 181
    • 34247130917 scopus 로고    scopus 로고
    • Effect of 4-hydroxy-2-nonenal modification on alpha-synuclein aggregation
    • Qin, Z., Hu, D., Han, S., Reaney, S.H., Di Monte, D.A., Fink, A.L., Effect of 4-hydroxy-2-nonenal modification on alpha-synuclein aggregation. J. Biol. Chem. 282:8 (2007), 5862–5870.
    • (2007) J. Biol. Chem. , vol.282 , Issue.8 , pp. 5862-5870
    • Qin, Z.1    Hu, D.2    Han, S.3    Reaney, S.H.4    Di Monte, D.A.5    Fink, A.L.6
  • 183
    • 84874372615 scopus 로고    scopus 로고
    • Oxidative stress-induced posttranslational modifications of alpha-synuclein: specific modification of alpha-synuclein by 4-hydroxy-2-nonenal increases dopaminergic toxicity
    • Xiang, W., Schlachetzki, J.C., Helling, S., Bussmann, J.C., Berlinghof, M., Schäffer, T.E., Marcus, K., Winkler, J., Klucken, J., Becker, C.M., Oxidative stress-induced posttranslational modifications of alpha-synuclein: specific modification of alpha-synuclein by 4-hydroxy-2-nonenal increases dopaminergic toxicity. Mol. Cell Neurosci. 54 (2013), 71–83.
    • (2013) Mol. Cell Neurosci. , vol.54 , pp. 71-83
    • Xiang, W.1    Schlachetzki, J.C.2    Helling, S.3    Bussmann, J.C.4    Berlinghof, M.5    Schäffer, T.E.6    Marcus, K.7    Winkler, J.8    Klucken, J.9    Becker, C.M.10
  • 184
    • 79151470406 scopus 로고    scopus 로고
    • The lipid peroxidation products 4-oxo-2-nonenal and 4-hydroxy-2-nonenal promote the formation of α-synuclein oligomers with distinct biochemical, morphological, and functional properties
    • Näsström, T., Fagerqvist, T., Barbu, M., Karlsson, M., Nikolajeff, F., Kasrayan, A., Ekberg, M., Lannfelt, L., Ingelsson, M., Bergström, J., The lipid peroxidation products 4-oxo-2-nonenal and 4-hydroxy-2-nonenal promote the formation of α-synuclein oligomers with distinct biochemical, morphological, and functional properties. Free Radic. Biol. Med. 50:3 (2011), 428–437.
    • (2011) Free Radic. Biol. Med. , vol.50 , Issue.3 , pp. 428-437
    • Näsström, T.1    Fagerqvist, T.2    Barbu, M.3    Karlsson, M.4    Nikolajeff, F.5    Kasrayan, A.6    Ekberg, M.7    Lannfelt, L.8    Ingelsson, M.9    Bergström, J.10
  • 185
    • 81055127451 scopus 로고    scopus 로고
    • Rapid, complete and large-scale generation of post-mitotic neurons from the human LUHMES cell line
    • Scholz, D., Pöltl, D., Genewsky, A., Weng, M., Waldmann, T., Schildknecht, S., Leist, M., Rapid, complete and large-scale generation of post-mitotic neurons from the human LUHMES cell line. J. Neurochem. 119:5 (2011), 957–971.
    • (2011) J. Neurochem. , vol.119 , Issue.5 , pp. 957-971
    • Scholz, D.1    Pöltl, D.2    Genewsky, A.3    Weng, M.4    Waldmann, T.5    Schildknecht, S.6    Leist, M.7
  • 187
    • 0033588087 scopus 로고    scopus 로고
    • 4-Hydroxy-2-nonenal-mediated impairment of intracellular proteolysis during oxidative stress. Identification of proteasomes as target molecules
    • Okada, K., Wangpoengtrakul, C., Osawa, T., Toyokuni, S., Tanaka, K., Uchida, K., 4-Hydroxy-2-nonenal-mediated impairment of intracellular proteolysis during oxidative stress. Identification of proteasomes as target molecules. J. Biol. Chem. 274:34 (1999), 23787–23793.
    • (1999) J. Biol. Chem. , vol.274 , Issue.34 , pp. 23787-23793
    • Okada, K.1    Wangpoengtrakul, C.2    Osawa, T.3    Toyokuni, S.4    Tanaka, K.5    Uchida, K.6
  • 189
    • 0037418629 scopus 로고    scopus 로고
    • Modulation of D1-like dopamine receptor function by aldehydic products of lipid peroxidation
    • Shin, Y., White, B.H., Uh, M., Sidhu, A., Modulation of D1-like dopamine receptor function by aldehydic products of lipid peroxidation. Brain Res. 968:1 (2003), 102–113.
    • (2003) Brain Res. , vol.968 , Issue.1 , pp. 102-113
    • Shin, Y.1    White, B.H.2    Uh, M.3    Sidhu, A.4
  • 192
    • 0028889913 scopus 로고
    • Cerebrospinal fluid of Parkinson's disease patients inhibits the growth and function of dopaminergic neurons in culture
    • Hao, R., Norgren, R.B. Jr, Lau, Y.S., Pfeiffer, R.F., Cerebrospinal fluid of Parkinson's disease patients inhibits the growth and function of dopaminergic neurons in culture. Neurology 45:1 (1995), 138–142.
    • (1995) Neurology , vol.45 , Issue.1 , pp. 138-142
    • Hao, R.1    Norgren, R.B.2    Lau, Y.S.3    Pfeiffer, R.F.4
  • 193
    • 0032527641 scopus 로고    scopus 로고
    • (E)-4-hydroxy-2-nonenal may be involved in the pathogenesis of Parkinson's disease
    • Selley, M.L., (E)-4-hydroxy-2-nonenal may be involved in the pathogenesis of Parkinson's disease. Free Radic. Biol. Med. 25:2 (1998), 169–174.
    • (1998) Free Radic. Biol. Med. , vol.25 , Issue.2 , pp. 169-174
    • Selley, M.L.1
  • 194
    • 15044364587 scopus 로고    scopus 로고
    • Treatment for the progression of Parkinson's disease
    • Calne, D., Schulzer, M., Mak, E., Stoessl, A.J., Treatment for the progression of Parkinson's disease. Lancet Neurol., 4(4), 2005, 206.
    • (2005) Lancet Neurol. , vol.4 , Issue.4 , pp. 206
    • Calne, D.1    Schulzer, M.2    Mak, E.3    Stoessl, A.J.4
  • 198
    • 35348938494 scopus 로고    scopus 로고
    • Anti-dyskinetic effects of cannabinoids in a rat model of Parkinson's disease: role of CB(1) and TRPV1 receptors
    • Morgese, M.G., Cassano, T., Cuomo, V., Giuffrida, A., Anti-dyskinetic effects of cannabinoids in a rat model of Parkinson's disease: role of CB(1) and TRPV1 receptors. Exp. Neurol. 208:1 (2007), 110–119.
    • (2007) Exp. Neurol. , vol.208 , Issue.1 , pp. 110-119
    • Morgese, M.G.1    Cassano, T.2    Cuomo, V.3    Giuffrida, A.4
  • 200
    • 77949495194 scopus 로고    scopus 로고
    • NMDA antagonist memantine improves levodopa-induced dyskinesias and “on-off” phenomena in Parkinson's disease
    • Varanese, S., Howard, J., Di Rocco, A., NMDA antagonist memantine improves levodopa-induced dyskinesias and “on-off” phenomena in Parkinson's disease. Mov. Disord. 25:4 (2010), 508–510.
    • (2010) Mov. Disord. , vol.25 , Issue.4 , pp. 508-510
    • Varanese, S.1    Howard, J.2    Di Rocco, A.3
  • 204
    • 34249794888 scopus 로고    scopus 로고
    • Neurotoxicity and metabolism of the catecholamine-derived 3,4-dihydroxyphenylacetaldehyde and 3,4-dihydroxyphenylglycolaldehyde: the role of aldehyde dehydrogenase
    • Marchitti, S.A., Deitrich, R.A., Vasiliou, V., Neurotoxicity and metabolism of the catecholamine-derived 3,4-dihydroxyphenylacetaldehyde and 3,4-dihydroxyphenylglycolaldehyde: the role of aldehyde dehydrogenase. Pharmacol. Rev. 59:2 (2007), 125–150.
    • (2007) Pharmacol. Rev. , vol.59 , Issue.2 , pp. 125-150
    • Marchitti, S.A.1    Deitrich, R.A.2    Vasiliou, V.3
  • 205
    • 78650789638 scopus 로고    scopus 로고
    • The neurotoxicity of DOPAL: behavioral and stereological evidence for its role in Parkinson disease pathogenesis
    • Panneton, W.M., Kumar, V.B., Gan, Q., Burke, W.J., Galvin, J.E., The neurotoxicity of DOPAL: behavioral and stereological evidence for its role in Parkinson disease pathogenesis. PLoS One, 5(12), 2010, e15251.
    • (2010) PLoS One , vol.5 , Issue.12 , pp. e15251
    • Panneton, W.M.1    Kumar, V.B.2    Gan, Q.3    Burke, W.J.4    Galvin, J.E.5
  • 207
    • 84857466337 scopus 로고    scopus 로고
    • Neurodegeneration and motor dysfunction in mice lacking cytosolic and mitochondrial aldehyde dehydrogenases: implications for Parkinson's disease
    • Wey, M.C., Fernandez, E., Martinez, P.A., Sullivan, P., Goldstein, D.S., Strong, R., Neurodegeneration and motor dysfunction in mice lacking cytosolic and mitochondrial aldehyde dehydrogenases: implications for Parkinson's disease. PLoS One, 7(2), 2012, e31522.
    • (2012) PLoS One , vol.7 , Issue.2 , pp. e31522
    • Wey, M.C.1    Fernandez, E.2    Martinez, P.A.3    Sullivan, P.4    Goldstein, D.S.5    Strong, R.6
  • 210
    • 84958230820 scopus 로고    scopus 로고
    • Mechanisms of Neuroprotection by Quercetin: Counteracting Oxidative Stress and More
    • Costa, L.G., Garrick, J.M., Roquè, P.J., Pellacani, C., Mechanisms of Neuroprotection by Quercetin: Counteracting Oxidative Stress and More. Oxid. Med. Cell Longev., 2016, 2016, 2986796.
    • (2016) Oxid. Med. Cell Longev. , vol.2016 , pp. 2986796
    • Costa, L.G.1    Garrick, J.M.2    Roquè, P.J.3    Pellacani, C.4
  • 211
    • 84863258358 scopus 로고    scopus 로고
    • Effect of Quercetin in the 1‐Methyl‐4‐phenyl‐1, 2, 3, 6‐tetrahydropyridine‐Induced Mouse Model of Parkinson's Disease
    • Lv, C., Hong, T., Yang, Z., Zhang, Y., Wang, L., Dong, M., Zhao, J., Mu, J., Meng, Y., Effect of Quercetin in the 1‐Methyl‐4‐phenyl‐1, 2, 3, 6‐tetrahydropyridine‐Induced Mouse Model of Parkinson's Disease. Evid. Based Complement. Altern. Med., 2012, 2012, 928643.
    • (2012) Evid. Based Complement. Altern. Med. , vol.2012 , pp. 928643
    • Lv, C.1    Hong, T.2    Yang, Z.3    Zhang, Y.4    Wang, L.5    Dong, M.6    Zhao, J.7    Mu, J.8    Meng, Y.9
  • 212
    • 84971671511 scopus 로고    scopus 로고
    • Ameliorative Effect of Quercetin on Neurochemical and Behavioral Deficits in Rotenone Rat Model of Parkinson's Disease: Modulating Autophagy (Quercetin on Experimental Parkinson's Disease)
    • El-Horany, H.E., El-Latif, R.N., ElBatsh, M.M., Emam, M.N., Ameliorative Effect of Quercetin on Neurochemical and Behavioral Deficits in Rotenone Rat Model of Parkinson's Disease: Modulating Autophagy (Quercetin on Experimental Parkinson's Disease). J. Biochem. Mol. Toxicol. 30:7 (2016), 360–369.
    • (2016) J. Biochem. Mol. Toxicol. , vol.30 , Issue.7 , pp. 360-369
    • El-Horany, H.E.1    El-Latif, R.N.2    ElBatsh, M.M.3    Emam, M.N.4
  • 214
  • 216
    • 84891866326 scopus 로고    scopus 로고
    • Environmental toxins and Parkinson's disease
    • Goldman, S., Environmental toxins and Parkinson's disease. Annu. Rev. Pharmacol. Toxicol. 54 (2014), 141–164.
    • (2014) Annu. Rev. Pharmacol. Toxicol. , vol.54 , pp. 141-164
    • Goldman, S.1
  • 218
    • 0025648166 scopus 로고
    • Cellular distribution of transferrin, ferritin, and iron in normal and aged human brains
    • Connor, J.R., Menzies, S.L., St Martin, S.M., Mufson, E.J., Cellular distribution of transferrin, ferritin, and iron in normal and aged human brains. J. Neurosci. Res. 27:4 (1990), 595–611.
    • (1990) J. Neurosci. Res. , vol.27 , Issue.4 , pp. 595-611
    • Connor, J.R.1    Menzies, S.L.2    St Martin, S.M.3    Mufson, E.J.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.