메뉴 건너뛰기




Volumn 74, Issue , 2015, Pages 295-304

Activation of PPAR gamma receptors reduces levodopa-induced dyskinesias in 6-OHDA-lesioned rats

Author keywords

Cannabinoid; Dyskinesia; Levodopa; Parkinson's disease; PPAR ; Rosiglitazone

Indexed keywords

2 [4 [2 [3 CYCLOHEXYL 1 (4 CYCLOHEXYLBUTYL)UREIDO]ETHYL]PHENYLTHIO] 2 METHYLPROPIONIC ACID; ANANDAMIDE; BENSERAZIDE; CAPSAZEPINE; CYCLOHEXYLCARBAMIC ACID 3' CARBAMOYLBIPHENYL 3 YL ESTER; DOPAMINE; DYNORPHIN; EARLY GROWTH RESPONSE FACTOR 1; LEVODOPA; MITOGEN ACTIVATED PROTEIN KINASE; N OLEOYLETHANOLAMINE; OXIDOPAMINE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PIRINIXIC ACID; ROSIGLITAZONE; 2,4 THIAZOLIDINEDIONE DERIVATIVE; ANTIPARKINSON AGENT; EGR1 PROTEIN, RAT;

EID: 84919359735     PISSN: 09699961     EISSN: 1095953X     Source Type: Journal    
DOI: 10.1016/j.nbd.2014.11.024     Document Type: Article
Times cited : (52)

References (72)
  • 1
    • 33646540419 scopus 로고    scopus 로고
    • A peroxisome proliferator-activated receptor-gamma agonist, troglitazone, facilitates caspase-8 and -9 activities by increasing the enzymatic activity of protein-tyrosine phosphatase-1B on human glioma cells
    • Akasaki Y., et al. A peroxisome proliferator-activated receptor-gamma agonist, troglitazone, facilitates caspase-8 and -9 activities by increasing the enzymatic activity of protein-tyrosine phosphatase-1B on human glioma cells. J. Biol. Chem. 2006, 281(10):6165-6174.
    • (2006) J. Biol. Chem. , vol.281 , Issue.10 , pp. 6165-6174
    • Akasaki, Y.1
  • 2
    • 0033428178 scopus 로고    scopus 로고
    • Striatal fosB expression is causally linked with l-DOPA-induced abnormal involuntary movements and the associated upregulation of striatal prodynorphin mRNA in a rat model of Parkinson's disease
    • Andersson M., Hilbertson A., Cenci M.A. Striatal fosB expression is causally linked with l-DOPA-induced abnormal involuntary movements and the associated upregulation of striatal prodynorphin mRNA in a rat model of Parkinson's disease. Neurobiol. Dis. 1999, 6(6):461-474.
    • (1999) Neurobiol. Dis. , vol.6 , Issue.6 , pp. 461-474
    • Andersson, M.1    Hilbertson, A.2    Cenci, M.A.3
  • 3
    • 84886263429 scopus 로고    scopus 로고
    • Immediate-early gene expression in structures outside the basal ganglia is associated to l-DOPA-induced dyskinesia
    • Bastide M.F., et al. Immediate-early gene expression in structures outside the basal ganglia is associated to l-DOPA-induced dyskinesia. Neurobiol. Dis. 2013, 62C:179-192.
    • (2013) Neurobiol. Dis. , vol.62 C , pp. 179-192
    • Bastide, M.F.1
  • 4
    • 0034057069 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptors in the cardiovascular system
    • Bishop-Bailey D. Peroxisome proliferator-activated receptors in the cardiovascular system. Br. J. Pharmacol. 2000, 129(5):823-834.
    • (2000) Br. J. Pharmacol. , vol.129 , Issue.5 , pp. 823-834
    • Bishop-Bailey, D.1
  • 5
    • 0028057911 scopus 로고
    • Buspirone in levodopa-induced dyskinesias
    • Bonifati V., et al. Buspirone in levodopa-induced dyskinesias. Clin. Neuropharmacol. 1994, 17(1):73-82.
    • (1994) Clin. Neuropharmacol. , vol.17 , Issue.1 , pp. 73-82
    • Bonifati, V.1
  • 6
    • 22144477527 scopus 로고    scopus 로고
    • Anandamide induced PPARgamma transcriptional activation and 3T3-L1 preadipocyte differentiation
    • Bouaboula M., et al. Anandamide induced PPARgamma transcriptional activation and 3T3-L1 preadipocyte differentiation. Eur. J. Pharmacol. 2005, 517(3):174-181.
    • (2005) Eur. J. Pharmacol. , vol.517 , Issue.3 , pp. 174-181
    • Bouaboula, M.1
  • 7
    • 0036326074 scopus 로고    scopus 로고
    • Protective action of the peroxisome proliferator-activated receptor-gamma agonist pioglitazone in a mouse model of Parkinson's disease
    • Breidert T., et al. Protective action of the peroxisome proliferator-activated receptor-gamma agonist pioglitazone in a mouse model of Parkinson's disease. J. Neurochem. 2002, 82(3):615-624.
    • (2002) J. Neurochem. , vol.82 , Issue.3 , pp. 615-624
    • Breidert, T.1
  • 8
    • 33846590071 scopus 로고    scopus 로고
    • Interaction with MEK causes nuclear export and downregulation of peroxisome proliferator-activated receptor gamma
    • Burgermeister E., et al. Interaction with MEK causes nuclear export and downregulation of peroxisome proliferator-activated receptor gamma. Mol. Cell. Biol. 2007, 27(3):803-817.
    • (2007) Mol. Cell. Biol. , vol.27 , Issue.3 , pp. 803-817
    • Burgermeister, E.1
  • 9
    • 84891600042 scopus 로고    scopus 로고
    • PPAR-gamma: therapeutic prospects in Parkinson's disease
    • Carta A.R. PPAR-gamma: therapeutic prospects in Parkinson's disease. Curr. Drug Targets 2013, 14(7):743-751.
    • (2013) Curr. Drug Targets , vol.14 , Issue.7 , pp. 743-751
    • Carta, A.R.1
  • 10
    • 0037013695 scopus 로고    scopus 로고
    • Differential regulation of GAD67, enkephalin and dynorphin mRNAs by chronic-intermittent L-dopa and A2A receptor blockade plus L-dopa in dopamine-denervated rats
    • Carta A.R., et al. Differential regulation of GAD67, enkephalin and dynorphin mRNAs by chronic-intermittent L-dopa and A2A receptor blockade plus L-dopa in dopamine-denervated rats. Synapse 2002, 44(3):166-174.
    • (2002) Synapse , vol.44 , Issue.3 , pp. 166-174
    • Carta, A.R.1
  • 11
    • 77954661327 scopus 로고    scopus 로고
    • Dyskinetic potential of dopamine agonists is associated with different striatonigral/striatopallidal zif-268 expression
    • Carta A.R., et al. Dyskinetic potential of dopamine agonists is associated with different striatonigral/striatopallidal zif-268 expression. Exp. Neurol. 2010, 224(2):395-402.
    • (2010) Exp. Neurol. , vol.224 , Issue.2 , pp. 395-402
    • Carta, A.R.1
  • 12
    • 80053092797 scopus 로고    scopus 로고
    • Rosiglitazone decreases peroxisome proliferator receptor-gamma levels in microglia and inhibits TNF-alpha production: new evidences on neuroprotection in a progressive Parkinson's disease model
    • Carta A.R., et al. Rosiglitazone decreases peroxisome proliferator receptor-gamma levels in microglia and inhibits TNF-alpha production: new evidences on neuroprotection in a progressive Parkinson's disease model. Neuroscience 2011, 194:250-261.
    • (2011) Neuroscience , vol.194 , pp. 250-261
    • Carta, A.R.1
  • 13
    • 77955380256 scopus 로고    scopus 로고
    • Maladaptive striatal plasticity in L-DOPA-induced dyskinesia
    • Cenci M.A., Konradi C. Maladaptive striatal plasticity in L-DOPA-induced dyskinesia. Prog. Brain Res. 2010, 183:209-233.
    • (2010) Prog. Brain Res. , vol.183 , pp. 209-233
    • Cenci, M.A.1    Konradi, C.2
  • 14
    • 0031925945 scopus 로고    scopus 로고
    • L-DOPA-induced dyskinesia in the rat is associated with striatal overexpression of prodynorphin- and glutamic acid decarboxylase mRNA
    • Cenci M.A., Lee C.S., Bjorklund A. L-DOPA-induced dyskinesia in the rat is associated with striatal overexpression of prodynorphin- and glutamic acid decarboxylase mRNA. Eur. J. Neurosci. 1998, 10(8):2694-2706.
    • (1998) Eur. J. Neurosci. , vol.10 , Issue.8 , pp. 2694-2706
    • Cenci, M.A.1    Lee, C.S.2    Bjorklund, A.3
  • 15
    • 0032889986 scopus 로고    scopus 로고
    • Biochemical and anatomical characterization of forepaw adjusting steps in rat models of Parkinson's disease: studies on medial forebrain bundle and striatal lesions
    • Chang J.W., et al. Biochemical and anatomical characterization of forepaw adjusting steps in rat models of Parkinson's disease: studies on medial forebrain bundle and striatal lesions. Neuroscience 1999, 88(2):617-628.
    • (1999) Neuroscience , vol.88 , Issue.2 , pp. 617-628
    • Chang, J.W.1
  • 16
    • 12344315682 scopus 로고    scopus 로고
    • Expression of peroxisome proliferator-activated receptors (PPARs) and retinoic acid receptors (RXRs) in rat cortical neurons
    • Cimini A., et al. Expression of peroxisome proliferator-activated receptors (PPARs) and retinoic acid receptors (RXRs) in rat cortical neurons. Neuroscience 2005, 130(2):325-337.
    • (2005) Neuroscience , vol.130 , Issue.2 , pp. 325-337
    • Cimini, A.1
  • 17
    • 59649111988 scopus 로고    scopus 로고
    • PPARs as new therapeutic targets for the treatment of cerebral ischemia/reperfusion injury
    • Collino M., Patel N.S., Thiemermann C. PPARs as new therapeutic targets for the treatment of cerebral ischemia/reperfusion injury. Ther. Adv. Cardiovasc. Dis. 2008, 2(3):179-197.
    • (2008) Ther. Adv. Cardiovasc. Dis. , vol.2 , Issue.3 , pp. 179-197
    • Collino, M.1    Patel, N.S.2    Thiemermann, C.3
  • 18
    • 0031930111 scopus 로고    scopus 로고
    • Distribution of mRNAs encoding the peroxisome proliferator-activated receptor alpha, beta, and gamma and the retinoid X receptor alpha, beta, and gamma in rat central nervous system
    • Cullingford T.E., et al. Distribution of mRNAs encoding the peroxisome proliferator-activated receptor alpha, beta, and gamma and the retinoid X receptor alpha, beta, and gamma in rat central nervous system. J. Neurochem. 1998, 70(4):1366-1375.
    • (1998) J. Neurochem. , vol.70 , Issue.4 , pp. 1366-1375
    • Cullingford, T.E.1
  • 19
    • 0347087323 scopus 로고    scopus 로고
    • Protection by pioglitazone in the MPTP model of Parkinson's disease correlates with I kappa B alpha induction and block of NF kappa B and iNOS activation
    • Dehmer T., et al. Protection by pioglitazone in the MPTP model of Parkinson's disease correlates with I kappa B alpha induction and block of NF kappa B and iNOS activation. J. Neurochem. 2004, 88(2):494-501.
    • (2004) J. Neurochem. , vol.88 , Issue.2 , pp. 494-501
    • Dehmer, T.1
  • 20
    • 33947302427 scopus 로고    scopus 로고
    • Modulation of L-DOPA-induced abnormal involuntary movements by clinically tested compounds: further validation of the rat dyskinesia model
    • Dekundy A., et al. Modulation of L-DOPA-induced abnormal involuntary movements by clinically tested compounds: further validation of the rat dyskinesia model. Behav. Brain Res. 2007, 179(1):76-89.
    • (2007) Behav. Brain Res. , vol.179 , Issue.1 , pp. 76-89
    • Dekundy, A.1
  • 21
    • 79551662648 scopus 로고    scopus 로고
    • Enhanced striatal cholinergic neuronal activity mediates L-DOPA-induced dyskinesia in parkinsonian mice
    • Ding Y., et al. Enhanced striatal cholinergic neuronal activity mediates L-DOPA-induced dyskinesia in parkinsonian mice. Proc. Natl. Acad. Sci. U. S. A. 2011, 108(2):840-845.
    • (2011) Proc. Natl. Acad. Sci. U. S. A. , vol.108 , Issue.2 , pp. 840-845
    • Ding, Y.1
  • 22
    • 78650753240 scopus 로고    scopus 로고
    • Inhibition of Ras-guanine nucleotide-releasing factor 1 (Ras-GRF1) signaling in the striatum reverts motor symptoms associated with L-dopa-induced dyskinesia
    • Fasano S., et al. Inhibition of Ras-guanine nucleotide-releasing factor 1 (Ras-GRF1) signaling in the striatum reverts motor symptoms associated with L-dopa-induced dyskinesia. Proc. Natl. Acad. Sci. U. S. A. 2010, 107(50):21824-21829.
    • (2010) Proc. Natl. Acad. Sci. U. S. A. , vol.107 , Issue.50 , pp. 21824-21829
    • Fasano, S.1
  • 23
    • 15744385109 scopus 로고    scopus 로고
    • Characterization of the fatty acid amide hydrolase inhibitor cyclohexyl carbamic acid 3'-carbamoyl-biphenyl-3-yl ester (URB597): effects on anandamide and oleoylethanolamide deactivation
    • Fegley D., et al. Characterization of the fatty acid amide hydrolase inhibitor cyclohexyl carbamic acid 3'-carbamoyl-biphenyl-3-yl ester (URB597): effects on anandamide and oleoylethanolamide deactivation. J. Pharmacol. Exp. Ther. 2005, 313(1):352-358.
    • (2005) J. Pharmacol. Exp. Ther. , vol.313 , Issue.1 , pp. 352-358
    • Fegley, D.1
  • 24
    • 32644460092 scopus 로고    scopus 로고
    • From molecular action to physiological outputs: peroxisome proliferator-activated receptors are nuclear receptors at the crossroads of key cellular functions
    • Feige J.N., et al. From molecular action to physiological outputs: peroxisome proliferator-activated receptors are nuclear receptors at the crossroads of key cellular functions. Prog. Lipid Res. 2006, 45(2):120-159.
    • (2006) Prog. Lipid Res. , vol.45 , Issue.2 , pp. 120-159
    • Feige, J.N.1
  • 25
    • 2442677617 scopus 로고    scopus 로고
    • Experimental parkinsonism alters anandamide precursor synthesis, and functional deficits are improved by AM404: a modulator of endocannabinoid function
    • Fernandez-Espejo E., et al. Experimental parkinsonism alters anandamide precursor synthesis, and functional deficits are improved by AM404: a modulator of endocannabinoid function. Neuropsychopharmacology 2004, 29(6):1134-1142.
    • (2004) Neuropsychopharmacology , vol.29 , Issue.6 , pp. 1134-1142
    • Fernandez-Espejo, E.1
  • 26
    • 0141481993 scopus 로고    scopus 로고
    • Effects of levodopa on endocannabinoid levels in rat basal ganglia: implications for the treatment of levodopa-induced dyskinesias
    • Ferrer B., et al. Effects of levodopa on endocannabinoid levels in rat basal ganglia: implications for the treatment of levodopa-induced dyskinesias. Eur. J. Neurosci. 2003, 18(6):1607-1614.
    • (2003) Eur. J. Neurosci. , vol.18 , Issue.6 , pp. 1607-1614
    • Ferrer, B.1
  • 27
    • 84855341776 scopus 로고    scopus 로고
    • L-DOPA-induced dyskinesia and abnormal signaling in striatal medium spiny neurons: focus on dopamine D1 receptor-mediated transmission
    • Feyder M., Bonito-Oliva A., Fisone G. L-DOPA-induced dyskinesia and abnormal signaling in striatal medium spiny neurons: focus on dopamine D1 receptor-mediated transmission. Front. Behav. Neurosci. 2011, 5:71.
    • (2011) Front. Behav. Neurosci. , vol.5 , pp. 71
    • Feyder, M.1    Bonito-Oliva, A.2    Fisone, G.3
  • 28
    • 19444372260 scopus 로고    scopus 로고
    • Oleoylethanolamide, an endogenous PPAR-alpha agonist, lowers body weight and hyperlipidemia in obese rats
    • Fu J., et al. Oleoylethanolamide, an endogenous PPAR-alpha agonist, lowers body weight and hyperlipidemia in obese rats. Neuropharmacology 2005, 48(8):1147-1153.
    • (2005) Neuropharmacology , vol.48 , Issue.8 , pp. 1147-1153
    • Fu, J.1
  • 29
    • 44449167054 scopus 로고    scopus 로고
    • Placebo influences on dyskinesia in Parkinson's disease
    • Goetz C.G., et al. Placebo influences on dyskinesia in Parkinson's disease. Mov. Disord. 2008, 23(5):700-707.
    • (2008) Mov. Disord. , vol.23 , Issue.5 , pp. 700-707
    • Goetz, C.G.1
  • 30
    • 84887514200 scopus 로고    scopus 로고
    • Oleoylethanolamide reduces L-DOPA-induced dyskinesia via TRPV1 receptor in a mouse model of Parkinson s disease
    • Gonzalez-Aparicio R., Moratalla R. Oleoylethanolamide reduces L-DOPA-induced dyskinesia via TRPV1 receptor in a mouse model of Parkinson s disease. Neurobiol. Dis. 2013, 62C:416-425.
    • (2013) Neurobiol. Dis. , vol.62 C , pp. 416-425
    • Gonzalez-Aparicio, R.1    Moratalla, R.2
  • 31
    • 79959480359 scopus 로고    scopus 로고
    • Therapies for dopaminergic-induced dyskinesias in Parkinson disease
    • Gottwald M.D., Aminoff M.J. Therapies for dopaminergic-induced dyskinesias in Parkinson disease. Ann. Neurol. 2011, 69(6):919-927.
    • (2011) Ann. Neurol. , vol.69 , Issue.6 , pp. 919-927
    • Gottwald, M.D.1    Aminoff, M.J.2
  • 32
    • 0027972008 scopus 로고
    • The basal ganglia and adaptive motor control
    • Graybiel A.M., et al. The basal ganglia and adaptive motor control. Science 1994, 265(5180):1826-1831.
    • (1994) Science , vol.265 , Issue.5180 , pp. 1826-1831
    • Graybiel, A.M.1
  • 33
    • 67449106378 scopus 로고    scopus 로고
    • Low doses of sarizotan reduce dyskinesias and maintain antiparkinsonian efficacy of L-dopa in parkinsonian monkeys
    • Gregoire L., et al. Low doses of sarizotan reduce dyskinesias and maintain antiparkinsonian efficacy of L-dopa in parkinsonian monkeys. Parkinsonism Relat. Disord. 2009, 15(6):445-452.
    • (2009) Parkinsonism Relat. Disord. , vol.15 , Issue.6 , pp. 445-452
    • Gregoire, L.1
  • 34
    • 34548823236 scopus 로고    scopus 로고
    • Changes in the prodynorphin gene and DARPP-32 state in 6-OHDA-lesioned rats following long-term treatment with l-dopa
    • Guan Q., et al. Changes in the prodynorphin gene and DARPP-32 state in 6-OHDA-lesioned rats following long-term treatment with l-dopa. Neurosci. Lett. 2007, 426(1):64-68.
    • (2007) Neurosci. Lett. , vol.426 , Issue.1 , pp. 64-68
    • Guan, Q.1
  • 35
    • 0032444348 scopus 로고    scopus 로고
    • Inducible and constitutive transcription factors in the mammalian nervous system: control of gene expression by Jun, Fos and Krox, and CREB/ATF proteins
    • Herdegen T., Leah J.D. Inducible and constitutive transcription factors in the mammalian nervous system: control of gene expression by Jun, Fos and Krox, and CREB/ATF proteins. Brain Res. Brain Res. Rev. 1998, 28(3):370-490.
    • (1998) Brain Res. Brain Res. Rev. , vol.28 , Issue.3 , pp. 370-490
    • Herdegen, T.1    Leah, J.D.2
  • 36
    • 84867362613 scopus 로고    scopus 로고
    • Chemical proteomics-based analysis of off-target binding profiles for rosiglitazone and pioglitazone: clues for assessing potential for cardiotoxicity
    • Hoffmann B.R., et al. Chemical proteomics-based analysis of off-target binding profiles for rosiglitazone and pioglitazone: clues for assessing potential for cardiotoxicity. J. Med. Chem. 2012, 55(19):8260-8271.
    • (2012) J. Med. Chem. , vol.55 , Issue.19 , pp. 8260-8271
    • Hoffmann, B.R.1
  • 37
    • 49649094091 scopus 로고    scopus 로고
    • The role of Wnt signaling in neuronal dysfunction in Alzheimer's disease
    • Inestrosa N.C., Toledo E.M. The role of Wnt signaling in neuronal dysfunction in Alzheimer's disease. Mol. Neurodegener. 2008, 3:9.
    • (2008) Mol. Neurodegener. , vol.3 , pp. 9
    • Inestrosa, N.C.1    Toledo, E.M.2
  • 38
    • 0037234363 scopus 로고    scopus 로고
    • Modulation of anxiety through blockade of anandamide hydrolysis
    • Kathuria S., et al. Modulation of anxiety through blockade of anandamide hydrolysis. Nat. Med. 2003, 9(1):76-81.
    • (2003) Nat. Med. , vol.9 , Issue.1 , pp. 76-81
    • Kathuria, S.1
  • 39
    • 11844269951 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor-gamma agonist extends survival in transgenic mouse model of amyotrophic lateral sclerosis
    • Kiaei M., et al. Peroxisome proliferator-activated receptor-gamma agonist extends survival in transgenic mouse model of amyotrophic lateral sclerosis. Exp. Neurol. 2005, 191(2):331-336.
    • (2005) Exp. Neurol. , vol.191 , Issue.2 , pp. 331-336
    • Kiaei, M.1
  • 40
    • 26844468856 scopus 로고    scopus 로고
    • Proinflammatory stimulation and pioglitazone treatment regulate peroxisome proliferator-activated receptor gamma levels in peripheral blood mononuclear cells from healthy controls and multiple sclerosis patients
    • Klotz L., et al. Proinflammatory stimulation and pioglitazone treatment regulate peroxisome proliferator-activated receptor gamma levels in peripheral blood mononuclear cells from healthy controls and multiple sclerosis patients. J. Immunol. 2005, 175(8):4948-4955.
    • (2005) J. Immunol. , vol.175 , Issue.8 , pp. 4948-4955
    • Klotz, L.1
  • 41
    • 0029962329 scopus 로고    scopus 로고
    • Validation of a rodent model of Parkinson's disease: evidence of a therapeutic window for oral Sinemet
    • Lindner M.D., et al. Validation of a rodent model of Parkinson's disease: evidence of a therapeutic window for oral Sinemet. Brain Res. Bull. 1996, 39(6):367-372.
    • (1996) Brain Res. Bull. , vol.39 , Issue.6 , pp. 367-372
    • Lindner, M.D.1
  • 42
    • 33751166817 scopus 로고    scopus 로고
    • Rapid broad-spectrum analgesia through activation of peroxisome proliferator-activated receptor-alpha
    • LoVerme J., et al. Rapid broad-spectrum analgesia through activation of peroxisome proliferator-activated receptor-alpha. J. Pharmacol. Exp. Ther. 2006, 319(3):1051-1061.
    • (2006) J. Pharmacol. Exp. Ther. , vol.319 , Issue.3 , pp. 1051-1061
    • LoVerme, J.1
  • 43
    • 0036459952 scopus 로고    scopus 로고
    • Pharmacological validation of behavioural measures of akinesia and dyskinesia in a rat model of Parkinson's disease
    • Lundblad M., et al. Pharmacological validation of behavioural measures of akinesia and dyskinesia in a rat model of Parkinson's disease. Eur. J. Neurosci. 2002, 15(1):120-132.
    • (2002) Eur. J. Neurosci. , vol.15 , Issue.1 , pp. 120-132
    • Lundblad, M.1
  • 44
    • 2342459797 scopus 로고    scopus 로고
    • A model of L-DOPA-induced dyskinesia in 6-hydroxydopamine lesioned mice: relation to motor and cellular parameters of nigrostriatal function
    • Lundblad M., et al. A model of L-DOPA-induced dyskinesia in 6-hydroxydopamine lesioned mice: relation to motor and cellular parameters of nigrostriatal function. Neurobiol. Dis. 2004, 16(1):110-123.
    • (2004) Neurobiol. Dis. , vol.16 , Issue.1 , pp. 110-123
    • Lundblad, M.1
  • 45
    • 19344378522 scopus 로고    scopus 로고
    • Pharmacological validation of a mouse model of l-DOPA-induced dyskinesia
    • Lundblad M., et al. Pharmacological validation of a mouse model of l-DOPA-induced dyskinesia. Exp. Neurol. 2005, 194(1):66-75.
    • (2005) Exp. Neurol. , vol.194 , Issue.1 , pp. 66-75
    • Lundblad, M.1
  • 46
    • 84856516709 scopus 로고    scopus 로고
    • The cannabinoid agonist WIN55212-2 decreases L-DOPA-induced PKA activation and dyskinetic behavior in 6-OHDA-treated rats
    • Martinez A., et al. The cannabinoid agonist WIN55212-2 decreases L-DOPA-induced PKA activation and dyskinetic behavior in 6-OHDA-treated rats. Neurosci. Res. 2012, 72(3):236-242.
    • (2012) Neurosci. Res. , vol.72 , Issue.3 , pp. 236-242
    • Martinez, A.1
  • 47
    • 0345118108 scopus 로고    scopus 로고
    • Immunolocalization of peroxisome proliferator-activated receptors and retinoid X receptors in the adult rat CNS
    • Moreno S., Farioli-Vecchioli S., Ceru M.P. Immunolocalization of peroxisome proliferator-activated receptors and retinoid X receptors in the adult rat CNS. Neuroscience 2004, 123(1):131-145.
    • (2004) Neuroscience , vol.123 , Issue.1 , pp. 131-145
    • Moreno, S.1    Farioli-Vecchioli, S.2    Ceru, M.P.3
  • 48
    • 35348938494 scopus 로고    scopus 로고
    • Anti-dyskinetic effects of cannabinoids in a rat model of Parkinson's disease: role of CB(1) and TRPV1 receptors
    • Morgese M.G., et al. Anti-dyskinetic effects of cannabinoids in a rat model of Parkinson's disease: role of CB(1) and TRPV1 receptors. Exp. Neurol. 2007, 208(1):110-119.
    • (2007) Exp. Neurol. , vol.208 , Issue.1 , pp. 110-119
    • Morgese, M.G.1
  • 49
    • 34250212715 scopus 로고    scopus 로고
    • Effect of rosiglitazone on the risk of myocardial infarction and death from cardiovascular causes
    • Nissen S.E., Wolski K. Effect of rosiglitazone on the risk of myocardial infarction and death from cardiovascular causes. N. Engl. J. Med. 2007, 356(24):2457-2471.
    • (2007) N. Engl. J. Med. , vol.356 , Issue.24 , pp. 2457-2471
    • Nissen, S.E.1    Wolski, K.2
  • 50
    • 35649008926 scopus 로고    scopus 로고
    • Cannabinoids go nuclear: evidence for activation of peroxisome proliferator-activated receptors
    • O'Sullivan S.E. Cannabinoids go nuclear: evidence for activation of peroxisome proliferator-activated receptors. Br. J. Pharmacol. 2007, 152(5):576-582.
    • (2007) Br. J. Pharmacol. , vol.152 , Issue.5 , pp. 576-582
    • O'Sullivan, S.E.1
  • 52
    • 0037141760 scopus 로고    scopus 로고
    • Modification of adenosine extracellular levels and adenosine A(2A) receptor mRNA by dopamine denervation
    • Pinna A., et al. Modification of adenosine extracellular levels and adenosine A(2A) receptor mRNA by dopamine denervation. Eur. J. Pharmacol. 2002, 446(1-3):75-82.
    • (2002) Eur. J. Pharmacol. , vol.446 , Issue.1-3 , pp. 75-82
    • Pinna, A.1
  • 53
    • 70349560028 scopus 로고    scopus 로고
    • The PPARalpha agonist fenofibrate preserves hippocampal neurogenesis and inhibits microglial activation after whole-brain irradiation
    • Ramanan S., et al. The PPARalpha agonist fenofibrate preserves hippocampal neurogenesis and inhibits microglial activation after whole-brain irradiation. Int. J. Radiat. Oncol. Biol. Phys. 2009, 75(3):870-877.
    • (2009) Int. J. Radiat. Oncol. Biol. Phys. , vol.75 , Issue.3 , pp. 870-877
    • Ramanan, S.1
  • 54
    • 0037378689 scopus 로고    scopus 로고
    • Limitations of current Parkinson's disease therapy
    • (discussion S12-5)
    • Rascol O., et al. Limitations of current Parkinson's disease therapy. Ann. Neurol. 2003, 53(Suppl. 3):S3-S12. (discussion S12-5).
    • (2003) Ann. Neurol. , vol.53 , pp. S3-S12
    • Rascol, O.1
  • 55
    • 0031886864 scopus 로고    scopus 로고
    • The peroxisome proliferator-activated receptor-gamma is a negative regulator of macrophage activation
    • Ricote M., et al. The peroxisome proliferator-activated receptor-gamma is a negative regulator of macrophage activation. Nature 1998, 391(6662):79-82.
    • (1998) Nature , vol.391 , Issue.6662 , pp. 79-82
    • Ricote, M.1
  • 56
    • 78149407291 scopus 로고    scopus 로고
    • Rosiglitazone reversal of Tg2576 cognitive deficits is independent of peripheral gluco-regulatory status
    • Rodriguez-Rivera J., Denner L., Dineley K.T. Rosiglitazone reversal of Tg2576 cognitive deficits is independent of peripheral gluco-regulatory status. Behav. Brain Res. 2011, 216(1):255-261.
    • (2011) Behav. Brain Res. , vol.216 , Issue.1 , pp. 255-261
    • Rodriguez-Rivera, J.1    Denner, L.2    Dineley, K.T.3
  • 57
    • 67649847847 scopus 로고    scopus 로고
    • Pharmacological modulation of glutamate transmission in a rat model of L-DOPA-induced dyskinesia: effects on motor behavior and striatal nuclear signaling
    • Rylander D., et al. Pharmacological modulation of glutamate transmission in a rat model of L-DOPA-induced dyskinesia: effects on motor behavior and striatal nuclear signaling. J. Pharmacol. Exp. Ther. 2009, 330(1):227-235.
    • (2009) J. Pharmacol. Exp. Ther. , vol.330 , Issue.1 , pp. 227-235
    • Rylander, D.1
  • 58
    • 34347357671 scopus 로고    scopus 로고
    • Critical involvement of cAMP/DARPP-32 and extracellular signal-regulated protein kinase signaling in L-DOPA-induced dyskinesia
    • Santini E., et al. Critical involvement of cAMP/DARPP-32 and extracellular signal-regulated protein kinase signaling in L-DOPA-induced dyskinesia. J. Neurosci. 2007, 27(26):6995-7005.
    • (2007) J. Neurosci. , vol.27 , Issue.26 , pp. 6995-7005
    • Santini, E.1
  • 59
    • 84865016327 scopus 로고    scopus 로고
    • Dopamine- and cAMP-regulated phosphoprotein of 32-kDa (DARPP-32)-dependent activation of extracellular signal-regulated kinase (ERK) and mammalian target of rapamycin complex 1 (mTORC1) signaling in experimental parkinsonism
    • Santini E., et al. Dopamine- and cAMP-regulated phosphoprotein of 32-kDa (DARPP-32)-dependent activation of extracellular signal-regulated kinase (ERK) and mammalian target of rapamycin complex 1 (mTORC1) signaling in experimental parkinsonism. J. Biol. Chem. 2012, 287(33):27806-27812.
    • (2012) J. Biol. Chem. , vol.287 , Issue.33 , pp. 27806-27812
    • Santini, E.1
  • 60
    • 61449237400 scopus 로고    scopus 로고
    • PPAR-gamma-mediated neuroprotection in a chronic mouse model of Parkinson's disease
    • Schintu N., et al. PPAR-gamma-mediated neuroprotection in a chronic mouse model of Parkinson's disease. Eur. J. Neurosci. 2009, 29(5):954-963.
    • (2009) Eur. J. Neurosci. , vol.29 , Issue.5 , pp. 954-963
    • Schintu, N.1
  • 61
    • 0033768218 scopus 로고    scopus 로고
    • Dyskinesias and motor fluctuations in Parkinson's disease: a community-based study
    • Schrag A., Quinn N. Dyskinesias and motor fluctuations in Parkinson's disease: a community-based study. Brain 2000, 123(Pt 11):2297-2305.
    • (2000) Brain , vol.123 , pp. 2297-2305
    • Schrag, A.1    Quinn, N.2
  • 62
    • 24144442457 scopus 로고    scopus 로고
    • Adolescent abuse of dextromethorphan
    • Schwartz R.H. Adolescent abuse of dextromethorphan. Clin. Pediatr. (Phila) 2005, 44(7):565-568.
    • (2005) Clin. Pediatr. (Phila) , vol.44 , Issue.7 , pp. 565-568
    • Schwartz, R.H.1
  • 63
    • 0025773753 scopus 로고
    • Molecular cloning and characterization of the promoter region of the mouse regulatory subunit RII beta of type II cAMP-dependent protein kinase
    • Singh I.S., et al. Molecular cloning and characterization of the promoter region of the mouse regulatory subunit RII beta of type II cAMP-dependent protein kinase. Biochem. Biophys. Res. Commun. 1991, 178(1):221-226.
    • (1991) Biochem. Biophys. Res. Commun. , vol.178 , Issue.1 , pp. 221-226
    • Singh, I.S.1
  • 64
    • 34250821923 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor alpha protects against obesity-induced hepatic inflammation
    • Stienstra R., et al. Peroxisome proliferator-activated receptor alpha protects against obesity-induced hepatic inflammation. Endocrinology 2007, 148(6):2753-2763.
    • (2007) Endocrinology , vol.148 , Issue.6 , pp. 2753-2763
    • Stienstra, R.1
  • 65
    • 0345863897 scopus 로고    scopus 로고
    • Duration of amantadine benefit on dyskinesia of severe Parkinson's disease
    • Thomas A., et al. Duration of amantadine benefit on dyskinesia of severe Parkinson's disease. J. Neurol. Neurosurg. Psychiatry 2004, 75(1):141-143.
    • (2004) J. Neurol. Neurosurg. Psychiatry , vol.75 , Issue.1 , pp. 141-143
    • Thomas, A.1
  • 66
    • 0031945065 scopus 로고    scopus 로고
    • A trial of dextromethorphan in parkinsonian patients with motor response complications
    • Verhagen Metman L., et al. A trial of dextromethorphan in parkinsonian patients with motor response complications. Mov. Disord. 1998, 13(3):414-417.
    • (1998) Mov. Disord. , vol.13 , Issue.3 , pp. 414-417
    • Verhagen Metman, L.1
  • 67
    • 34047178328 scopus 로고    scopus 로고
    • Spatiotemporal pattern of striatal ERK1/2 phosphorylation in a rat model of L-DOPA-induced dyskinesia and the role of dopamine D1 receptors
    • Westin J.E., et al. Spatiotemporal pattern of striatal ERK1/2 phosphorylation in a rat model of L-DOPA-induced dyskinesia and the role of dopamine D1 receptors. Biol. Psychiatry 2007, 62(7):800-810.
    • (2007) Biol. Psychiatry , vol.62 , Issue.7 , pp. 800-810
    • Westin, J.E.1
  • 68
    • 0036070538 scopus 로고    scopus 로고
    • L-DOPA-induced dyskinesia in the intrastriatal 6-hydroxydopamine model of parkinson's disease: relation to motor and cellular parameters of nigrostriatal function
    • Winkler C., et al. L-DOPA-induced dyskinesia in the intrastriatal 6-hydroxydopamine model of parkinson's disease: relation to motor and cellular parameters of nigrostriatal function. Neurobiol. Dis. 2002, 10(2):165-186.
    • (2002) Neurobiol. Dis. , vol.10 , Issue.2 , pp. 165-186
    • Winkler, C.1
  • 69
    • 0026703977 scopus 로고
    • Tissue-specific transcription of the rat tyrosine hydroxylase gene requires synergy between an AP-1 motif and an overlapping E box-containing dyad
    • Yoon S.O., Chikaraishi D.M. Tissue-specific transcription of the rat tyrosine hydroxylase gene requires synergy between an AP-1 motif and an overlapping E box-containing dyad. Neuron 1992, 9(1):55-67.
    • (1992) Neuron , vol.9 , Issue.1 , pp. 55-67
    • Yoon, S.O.1    Chikaraishi, D.M.2
  • 70
    • 84871259864 scopus 로고    scopus 로고
    • Retinoic acid induces neurogenesis by activating both retinoic acid receptors (RARs) and peroxisome proliferator-activated receptor beta/delta (PPARbeta/delta)
    • Yu S., et al. Retinoic acid induces neurogenesis by activating both retinoic acid receptors (RARs) and peroxisome proliferator-activated receptor beta/delta (PPARbeta/delta). J. Biol. Chem. 2012, 287(50):42195-42205.
    • (2012) J. Biol. Chem. , vol.287 , Issue.50 , pp. 42195-42205
    • Yu, S.1
  • 71
    • 33745983234 scopus 로고    scopus 로고
    • Activation of cerebral peroxisome proliferator-activated receptors gamma promotes neuroprotection by attenuation of neuronal cyclooxygenase-2 overexpression after focal cerebral ischemia in rats
    • Zhao Y., et al. Activation of cerebral peroxisome proliferator-activated receptors gamma promotes neuroprotection by attenuation of neuronal cyclooxygenase-2 overexpression after focal cerebral ischemia in rats. FASEB J. 2006, 20(8):1162-1175.
    • (2006) FASEB J. , vol.20 , Issue.8 , pp. 1162-1175
    • Zhao, Y.1
  • 72
    • 0026648761 scopus 로고
    • Characterization of gene organization and promoter region of the rat dopamine D1 receptor gene
    • Zhou Q.Y., Li C., Civelli O. Characterization of gene organization and promoter region of the rat dopamine D1 receptor gene. J. Neurochem. 1992, 59(5):1875-1883.
    • (1992) J. Neurochem. , vol.59 , Issue.5 , pp. 1875-1883
    • Zhou, Q.Y.1    Li, C.2    Civelli, O.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.