메뉴 건너뛰기




Volumn 22, Issue 18, 2015, Pages 1681-1702

Role of 4-hydroxynonenal-protein adducts in human diseases

Author keywords

[No Author keywords available]

Indexed keywords

4 HYDROXYNONENAL; LIPID; PROTEIN; 4-HYDROXY-2-NONENAL; ALDEHYDE;

EID: 84930613239     PISSN: 15230864     EISSN: 15577716     Source Type: Journal    
DOI: 10.1089/ars.2014.6166     Document Type: Review
Times cited : (104)

References (229)
  • 3
    • 84862849779 scopus 로고    scopus 로고
    • Antibodies against 4-hydroxy-2-nonenal modified epitopes recognized chromatin and its oxidized forms: Role of vhromatin, oxidized forms of chromatin and 4-hydroxy-2-nonenal modified epitopes on the etiopathogenesis of SLE
    • Al-Shobaili HA, Al Robaee AA, Alzolibani AA, and Rasheed Z. Antibodies against 4-hydroxy-2-nonenal modified epitopes recognized chromatin and its oxidized forms: role of vhromatin, oxidized forms of chromatin and 4-hydroxy-2-nonenal modified epitopes on the etiopathogenesis of SLE. Dis Markers 33: 19-34, 2012.
    • (2012) Dis Markers , vol.33 , pp. 19-34
    • Al-Shobaili, H.A.1    Al Robaee, A.A.2    Alzolibani, A.A.3    Rasheed, Z.4
  • 5
    • 0030815915 scopus 로고    scopus 로고
    • Coexpression of ICAM-1, VCAM-1, ELAM-1 and Hsp60 in human arterial and venous endothelial cells in response to cytokines and oxidized low-density lipoproteins
    • Amberger A, Maczek C, Jürgens G, Michaelis D, Schett G, Trieb K, Eberl T, indal S, Xu Q, and Wick G. Coexpression of ICAM-1, VCAM-1, ELAM-1 and Hsp60 in human arterial and venous endothelial cells in response to cytokines and oxidized low-density lipoproteins. Cell Stress Chaperones 22: 94-103, 1997.
    • (1997) Cell Stress Chaperones , vol.22 , pp. 94-103
    • Amberger, A.1    Maczek, C.2    Jürgens, G.3    Michaelis, D.4    Schett, G.5    Trieb, K.6    Eberl, T.7    Indal, S.8    Xu, Q.9    Wick, G.10
  • 6
    • 0029040462 scopus 로고
    • Evidence for the accumulation of lipid hydroperoxides during the aging of human red blood cells in the circulation
    • Ando K, Beppu M, and Kitagawa K. Evidence for the accumulation of lipid hydroperoxides during the aging of human red blood cells in the circulation. Biol Pharmacol Bull 18: 659-663, 1995.
    • (1995) Biol Pharmacol Bull , vol.18 , pp. 659-663
    • Ando, K.1    Beppu, M.2    Kitagawa, K.3
  • 7
    • 0031552061 scopus 로고    scopus 로고
    • The human ENO1 gene product (recombinant human alpha- enolase) displays characteristics required for a plasminogen binding protein
    • Andronicos NM, Ranson M, Bognacki J, and Baker MS. The human ENO1 gene product (recombinant human alpha- enolase) displays characteristics required for a plasminogen binding protein. Biochim Biophys Acta 1337: 27-39, 1997.
    • (1997) Biochim Biophys Acta , vol.1337 , pp. 27-39
    • Andronicos, N.M.1    Ranson, M.2    Bognacki, J.3    Baker, M.S.4
  • 8
    • 0033953940 scopus 로고    scopus 로고
    • LOX-1 mediates lysophosphatidylcholine-induced oxidized LDL uptake in smooth muscle cells
    • Aoyama T, Chen M, Fujiwara H, Masaki T, and Sawamura T. LOX-1 mediates lysophosphatidylcholine-induced oxidized LDL uptake in smooth muscle cells. FEBS Lett 467: 217-220, 2000.
    • (2000) FEBS Lett , vol.467 , pp. 217-220
    • Aoyama, T.1    Chen, M.2    Fujiwara, H.3    Masaki, T.4    Sawamura, T.5
  • 9
    • 73949083731 scopus 로고    scopus 로고
    • The covalent modification of spectrin in red cell membranes by the lipid peroxidation product 4-hydroxy- 2-nonenal
    • Arashiki N, Otsuka Y, Ito D, Komatsu T, Sato K, and Inaba M. The covalent modification of spectrin in red cell membranes by the lipid peroxidation product 4-hydroxy- 2-nonenal. Biochem Biophys Res Commun 391: 1543- 1547, 2010.
    • (2010) Biochem Biophys Res Commun , vol.391 , pp. 1543-1547
    • Arashiki, N.1    Otsuka, Y.2    Ito, D.3    Komatsu, T.4    Sato, K.5    Inaba, M.6
  • 10
    • 44849141174 scopus 로고    scopus 로고
    • Specific oxidized phospholipids inhibit scavenger receptor bi-mediated selective uptake of cholesteryl esters
    • Ashraf MZ, Kar NS, Chen X, Choi J, Salomon RG, Febbraio M, and Podrez EA. Specific oxidized phospholipids inhibit scavenger receptor bi-mediated selective uptake of cholesteryl esters. J Biol Chem 283: 10408-10414, 2008.
    • (2008) J Biol Chem , vol.283 , pp. 10408-10414
    • Ashraf, M.Z.1    Kar, N.S.2    Chen, X.3    Choi, J.4    Salomon, R.G.5    Febbraio, M.6    Podrez, E.A.7
  • 12
    • 78650692177 scopus 로고    scopus 로고
    • Post-translational modification and regulation of glutamate cysteine ligase by the a, b-unsaturated aldehyde 4-Hydroxy-2-Nonenal (4-HNE)
    • Backos DS, Fritz KS, Roede JR, Petersen DR, and Franklin CC. Post-translational modification and regulation of glutamate cysteine ligase by the a, b-unsaturated aldehyde 4-Hydroxy-2-Nonenal (4-HNE). Free Radic Biol Med 50: 14-26, 2011.
    • (2011) Free Radic Biol Med , vol.50 , pp. 14-26
    • Backos, D.S.1    Fritz, K.S.2    Roede, J.R.3    Petersen, D.R.4    Franklin, C.C.5
  • 13
    • 84861601576 scopus 로고    scopus 로고
    • Heme oxygenase-1 posttranslational modifications in the brain of subjects with Alzheimer disease and mild cognitive impairment
    • Barone E, Di Domenico F, Sultana R, Coccia R, Mancuso C, Perluigi M, and Butterfield DA. Heme oxygenase-1 posttranslational modifications in the brain of subjects with Alzheimer disease and mild cognitive impairment. Free Radic Biol Med 52: 2292-2301, 2012.
    • (2012) Free Radic Biol Med , vol.52 , pp. 2292-2301
    • Barone, E.1    Di Domenico, F.2    Sultana, R.3    Coccia, R.4    Mancuso, C.5    Perluigi, M.6    Butterfield, D.A.7
  • 14
    • 84883890972 scopus 로고    scopus 로고
    • Oxidative stress and lipid peroxidation products in cancer progression and therapy
    • Barrera G. Oxidative stress and lipid peroxidation products in cancer progression and therapy. ISRN Oncol 2012: 137289, 2012.
    • (2012) ISRN Oncol , vol.2012
    • Barrera, G.1
  • 15
    • 39749147206 scopus 로고    scopus 로고
    • Lipid peroxidation: Control of cell proliferation, cell differentiation and cell death
    • Barrera G, Pizzimenti S, and Dianzani MU. Lipid peroxidation: control of cell proliferation, cell differentiation and cell death. Mol Aspects Med 29: 1-8, 2008.
    • (2008) Mol Aspects Med , vol.29 , pp. 1-8
    • Barrera, G.1    Pizzimenti, S.2    Dianzani, M.U.3
  • 17
    • 0030836707 scopus 로고    scopus 로고
    • 4-Hydroxynonenal, an aldehydic product of lipid peroxidation, impairs signal transduction associated with muscarinic acetylcholine and metabotropic glutamate receptors: Possible action on G alpha(q/11)
    • Blanc EM, Kelly JF, Mark RJ, Waeg G, and Mattson MP. 4-Hydroxynonenal, an aldehydic product of lipid peroxidation, impairs signal transduction associated with muscarinic acetylcholine and metabotropic glutamate receptors: possible action on G alpha(q/11). J Neurochem 69: 570-580, 2007.
    • (2007) J Neurochem , vol.69 , pp. 570-580
    • Blanc, E.M.1    Kelly, J.F.2    Mark, R.J.3    Waeg, G.4    Mattson, M.P.5
  • 21
    • 54049097551 scopus 로고    scopus 로고
    • Ferritin and FasL (CD95L) mediate density dependent apoptosis in primary rat hepatocytes
    • Bresgen N, Ohlenschlager I, Wacht N, Afazel S, Ladurner G, and Eckl PM. Ferritin and FasL (CD95L) mediate density dependent apoptosis in primary rat hepatocytes. J Cell Physiol 217: 800-808, 2008.
    • (2008) J Cell Physiol , vol.217 , pp. 800-808
    • Bresgen, N.1    Ohlenschlager, I.2    Wacht, N.3    Afazel, S.4    Ladurner, G.5    Eckl, P.M.6
  • 23
    • 0028986075 scopus 로고
    • Control of i kappa B-alpha proteolysis by site-specific, signal-induced phosphorylation
    • Brown K, Gerstberger S, Carlson L, Franzoso G, and Siebenlist U. Control of I kappa B-alpha proteolysis by site-specific, signal-induced phosphorylation. Science 267: 1485-1488, 1995.
    • (1995) Science , vol.267 , pp. 1485-1488
    • Brown, K.1    Gerstberger, S.2    Carlson, L.3    Franzoso, G.4    Siebenlist, U.5
  • 24
    • 33947675275 scopus 로고    scopus 로고
    • Oxidative damage in Huntington's disease pathogenesis
    • Browne SE and Beal MF. Oxidative damage in Huntington's disease pathogenesis. Antioxid Redox Signal 8: 2061-2073, 2006.
    • (2006) Antioxid Redox Signal , vol.8 , pp. 2061-2073
    • Browne, S.E.1    Beal, M.F.2
  • 25
    • 79955836706 scopus 로고    scopus 로고
    • Identification of new autoantibody specificities directed at proteins involved in the transforming growth factor b pathway in patients with systemic sclerosis
    • Bussone G, Dib H, Tamby MC, Broussard C, Federici C, Woimant G, Camoin L, Guillevin L, and Mouthon L. Identification of new autoantibody specificities directed at proteins involved in the transforming growth factor b pathway in patients with systemic sclerosis. Arthritis Res Ther 13: 74, 2011.
    • Arthritis Res Ther , vol.13 , Issue.74 , pp. 2011
    • Bussone, G.1    Dib, H.2    Tamby, M.C.3    Broussard, C.4    Federici, C.5    Woimant, G.6    Camoin, L.7    Guillevin, L.8    Mouthon, L.9
  • 26
    • 0035194145 scopus 로고    scopus 로고
    • Evidence of oxidative damage in Alzheimer's disease brain: Central role for amyloid beta-peptide
    • Butterfield DA, Drake J, Pocernich C, and Castegna A. Evidence of oxidative damage in Alzheimer's disease brain: central role for amyloid beta-peptide. Trends Mol Med 7: 548-554, 2001.
    • (2001) Trends Mol Med , vol.7 , pp. 548-554
    • Butterfield, D.A.1    Drake, J.2    Pocernich, C.3    Castegna, A.4
  • 27
    • 78650147789 scopus 로고    scopus 로고
    • Roles of 3-nitrotyrosine- and 4-hydroxynonenal-modified brain proteins in the progression and pathogenesis of Alzheimer's disease
    • Butterfield DA, Reed T, and Sultana R. Roles of 3-nitrotyrosine- and 4-hydroxynonenal-modified brain proteins in the progression and pathogenesis of Alzheimer's disease. Free Radic Res 45: 59-72, 2011.
    • (2011) Free Radic Res , vol.45 , pp. 59-72
    • Butterfield, D.A.1    Reed, T.2    Sultana, R.3
  • 28
    • 0027456540 scopus 로고
    • Glutathione-S-transferase, alcohol dehydrogenase and aldehyde reductase activities during diethylnitrosamine- carcinogenesis in rat liver
    • Canuto RA, Muzio G, Maggiora M, Biocca ME, and Dianzani MU. Glutathione-S-transferase, alcohol dehydrogenase and aldehyde reductase activities during diethylnitrosamine- carcinogenesis in rat liver. Cancer Lett 68: 177-183, 1993.
    • (1993) Cancer Lett , vol.68 , pp. 177-183
    • Canuto, R.A.1    Muzio, G.2    Maggiora, M.3    Biocca, M.E.4    Dianzani, M.U.5
  • 29
    • 0028288510 scopus 로고
    • Autoantigens targeted in sistemic lupus erythematosus are clustered in two populations of surface structures on apoptotic keratinocytes
    • Casciola-Rosen LA, Anhalt G, and Rosen A. Autoantigens targeted in sistemic lupus erythematosus are clustered in two populations of surface structures on apoptotic keratinocytes. J Exp Med 179: 1317-1330, 1994.
    • (1994) J Exp Med , vol.179 , pp. 1317-1330
    • Casciola-Rosen, L.A.1    Anhalt, G.2    Rosen, A.3
  • 30
    • 0033828142 scopus 로고    scopus 로고
    • Collagen type i synthesized by pancreatic periacinar stellate cells (PSC) co-localizes with lipid peroxidation-derived aldehydes in chronic alcoholic pancreatitis
    • Casini A, Galli A, Pignalosa P, Frulloni L, Grappone C, Milani S, Pederzoli P, Cavallini G, and Surrenti C. Collagen type I synthesized by pancreatic periacinar stellate cells (PSC) co-localizes with lipid peroxidation-derived aldehydes in chronic alcoholic pancreatitis. J Pathol 192: 81-89, 2000.
    • (2000) J Pathol , vol.192 , pp. 81-89
    • Casini, A.1    Galli, A.2    Pignalosa, P.3    Frulloni, L.4    Grappone, C.5    Milani, S.6    Pederzoli, P.7    Cavallini, G.8    Surrenti, C.9
  • 31
    • 4444382031 scopus 로고    scopus 로고
    • Systemic lipid peroxidation and its metabolic and dietary correlates in patients with non-alcoholic steatohepatitis
    • Chalasani N, Deeg MA, and Crabb DW. Systemic lipid peroxidation and its metabolic and dietary correlates in patients with non-alcoholic steatohepatitis. Am J Gastroenterol 99: 1497-1502, 2004.
    • (2004) Am J Gastroenterol , vol.99 , pp. 1497-1502
    • Chalasani, N.1    Deeg, M.A.2    Crabb, D.W.3
  • 32
    • 1642566759 scopus 로고    scopus 로고
    • Autoreactive B cells in lupus-prone New Zealand black mice exhibit aberrant survival and proliferation in the presence of selfantigen in vivo
    • Chang NH, MacLeod R, and Wither JE. Autoreactive B cells in lupus-prone New Zealand black mice exhibit aberrant survival and proliferation in the presence of selfantigen in vivo. J Immunol 172: 1553-1560, 2004.
    • (2004) J Immunol , vol.172 , pp. 1553-1560
    • Chang, N.H.1    Macleod, R.2    Wither, J.E.3
  • 33
    • 0033625140 scopus 로고    scopus 로고
    • Increased expression of lectin-like oxidized low density lipoprotein receptor-1 in initial atherosclerotic lesions of Watanabe heritable hyperlipidemic rabbits
    • Chen M, Kakutani M, Minami M, Kataoka H, Kume N, Narumiya S, Kita T, Masaki T, and Sawamura T. Increased expression of lectin-like oxidized low density lipoprotein receptor-1 in initial atherosclerotic lesions of Watanabe heritable hyperlipidemic rabbits. Arterioscler Thromb Vasc Biol 20: 1107-1115, 2000.
    • (2000) Arterioscler Thromb Vasc Biol , vol.20 , pp. 1107-1115
    • Chen, M.1    Kakutani, M.2    Minami, M.3    Kataoka, H.4    Kume, N.5    Narumiya, S.6    Kita, T.7    Masaki, T.8    Sawamura, T.9
  • 35
    • 1842581669 scopus 로고    scopus 로고
    • Oxidative modifications and downregulation of ubiquitin carboxyl-terminal hydrolase L1 associated with idiopathic Parkinson's and Alzheimer's diseases
    • Choi J, Levey AI, Weintraub ST, Rees HD, Gearing M, Chin LS, and Li L. Oxidative modifications and downregulation of ubiquitin carboxyl-terminal hydrolase L1 associated with idiopathic Parkinson's and Alzheimer's diseases. J Biol Chem 279: 13256-13264, 2004.
    • (2004) J Biol Chem , vol.279 , pp. 13256-13264
    • Choi, J.1    Levey, A.I.2    Weintraub, S.T.3    Rees, H.D.4    Gearing, M.5    Chin, L.S.6    Li, L.7
  • 36
    • 15744398884 scopus 로고    scopus 로고
    • Oxidative modifications and aggregation of Cu, Znsuperoxide dismutase associated with Alzheimer and Parkinson diseases
    • Choi J, Rees HD, Weintraub ST, Levey AI, Chin LS, and Li L. Oxidative modifications and aggregation of Cu, Znsuperoxide dismutase associated with Alzheimer and Parkinson diseases. J Biol Chem 280: 11648-11655, 2005.
    • (2005) J Biol Chem , vol.280 , pp. 11648-11655
    • Choi, J.1    Rees, H.D.2    Weintraub, S.T.3    Levey, A.I.4    Chin, L.S.5    Li, L.6
  • 39
    • 79959214007 scopus 로고    scopus 로고
    • Lipid peroxidation of poly-unsaturated fatty acids in normal and obese adipose tissues
    • Cohen G, Riahi Y, and Sasson S. Lipid peroxidation of poly-unsaturated fatty acids in normal and obese adipose tissues. Arch Physiol Biochem 117: 131-139, 2011.
    • (2011) Arch Physiol Biochem , vol.117 , pp. 131-139
    • Cohen, G.1    Riahi, Y.2    Sasson, S.3
  • 40
    • 33947241783 scopus 로고    scopus 로고
    • The oxidative stress mediator 4-hydroxynonenal is an intracellular agonist of the nuclear receptor peroxisome proliferator- activated receptor-b/d (PPARb/d)
    • Coleman JD, Prabhu KS, Thompson JT, Reddy PS, Peters JM, Peterson BR, Reddy CC, and Vanden Heuvel JP. The oxidative stress mediator 4-hydroxynonenal is an intracellular agonist of the nuclear receptor peroxisome proliferator- activated receptor-b/d (PPARb/d). Free Radic Biol Med 42: 1155-1164, 2007.
    • (2007) Free Radic Biol Med , vol.42 , pp. 1155-1164
    • Coleman, J.D.1    Prabhu, K.S.2    Thompson, J.T.3    Reddy, P.S.4    Peters, J.M.5    Peterson, B.R.6    Reddy, C.C.7    Vanden Heuvel, J.P.8
  • 41
    • 0034724687 scopus 로고    scopus 로고
    • Oxidized low density lipoprotein (ox-LDL) binding to ox-LDL receptor-1 in endothelial cells induces the activation of NF-kappaB through an increased production of intracellular reactive oxygen species
    • Cominacini L, Pasini AF, Garbin U, Davoli A, Tosetti ML, Campagnola M, Rigoni A, Pastorino AM, Lo Cascio V, and Sawamura T. Oxidized low density lipoprotein (ox-LDL) binding to ox-LDL receptor-1 in endothelial cells induces the activation of NF-kappaB through an increased production of intracellular reactive oxygen species. J Biol Chem 275: 12633-12638, 2000.
    • (2000) J Biol Chem , vol.275 , pp. 12633-12638
    • Cominacini, L.1    Pasini, A.F.2    Garbin, U.3    Davoli, A.4    Tosetti, M.L.5    Campagnola, M.6    Rigoni, A.7    Pastorino, A.M.8    Lo Cascio, V.9    Sawamura, T.10
  • 42
    • 0035958019 scopus 로고    scopus 로고
    • The binding of oxidized low density lipoprotein (ox-LDL) to ox-LDL receptor-1 reduces the intracellular concentration of nitric oxide in endothelial cells through an increased production of superoxide
    • Cominacini L, Rigoni A, Pasini AF, Garbin U, Davoli A, Campagnola M, Pastorino AM, Lo Cascio V, and Sawamura T. The binding of oxidized low density lipoprotein (ox-LDL) to ox-LDL receptor-1 reduces the intracellular concentration of nitric oxide in endothelial cells through an increased production of superoxide. J Biol Chem 276: 13750-13755, 2001.
    • (2001) J Biol Chem , vol.276 , pp. 13750-13755
    • Cominacini, L.1    Rigoni, A.2    Pasini, A.F.3    Garbin, U.4    Davoli, A.5    Campagnola, M.6    Pastorino, A.M.7    Lo Cascio, V.8    Sawamura, T.9
  • 44
    • 0023685507 scopus 로고
    • Chemotactic activity of the lipid peroxidation product 4-hydroxynonenal and homologous hydroxyalkenals and consequences neutrophil motility
    • Curzio M, Esterbauer H, DiMauro C, Cecchini G, and Dianzani MU. Chemotactic activity of the lipid peroxidation product 4-hydroxynonenal and homologous hydroxyalkenals and consequences neutrophil motility. Free Rad Res Commun 5: 55-66, 1988.
    • (1988) Free Rad Res Commun , vol.5 , pp. 55-66
    • Curzio, M.1    Esterbauer, H.2    Dimauro, C.3    Cecchini, G.4    Dianzani, M.U.5
  • 47
    • 48449104184 scopus 로고    scopus 로고
    • FALDH reverses the deleterious action of oxidative stress induced by lipid peroxidation product 4-hydroxynonenal on insulin signaling in 3T3-L1 adipocytes
    • Demozay D, Mas JC, Rocchi S, and Van Obberghen E. FALDH reverses the deleterious action of oxidative stress induced by lipid peroxidation product 4-hydroxynonenal on insulin signaling in 3T3-L1 adipocytes. Diabetes 57: 1216-1226, 2008.
    • (2008) Diabetes , vol.57 , pp. 1216-1226
    • Demozay, D.1    Mas, J.C.2    Rocchi, S.3    Van Obberghen, E.4
  • 49
    • 0042671376 scopus 로고    scopus 로고
    • 4-Hydroxynonenal from pathology to physiology
    • Dianzani MU. 4-Hydroxynonenal from pathology to physiology. Mol Aspects Med 24: 263-272, 2003.
    • (2003) Mol Aspects Med , vol.24 , pp. 263-272
    • Dianzani, M.U.1
  • 50
    • 0027459113 scopus 로고
    • Mechanisms and biological relevance of lipid peroxidation initiation
    • Dix TA and Aikens J. Mechanisms and biological relevance of lipid peroxidation initiation. Chem Res Toxicol 6: 2-18, 1993.
    • (1993) Chem Res Toxicol , vol.6 , pp. 2-18
    • Dix, T.A.1    Aikens, J.2
  • 51
    • 84890822456 scopus 로고    scopus 로고
    • Inhibition of glycolysis attenuates 4-hydroxynonenal-dependent autophagy and exacerbates apoptosis in differentiated SH-SY5Y neuroblastoma cells
    • Dodson M, Liang Q, Johnson MS, Redmann M, Fineberg N, Darley-Usmar VM, and Zhang J. Inhibition of glycolysis attenuates 4-hydroxynonenal-dependent autophagy and exacerbates apoptosis in differentiated SH-SY5Y neuroblastoma cells. Autophagy 9: 1996-2008, 2013.
    • (2013) Autophagy , vol.9 , pp. 1996-2008
    • Dodson, M.1    Liang, Q.2    Johnson, M.S.3    Redmann, M.4    Fineberg, N.5    Darley-Usmar, V.M.6    Zhang, J.7
  • 52
    • 0034014222 scopus 로고    scopus 로고
    • TGF-beta1 downregulates CD36 and scavenger receptor A but upregulates LOX-1 in human macrophages
    • Draude G and Lorenz RL. TGF-beta1 downregulates CD36 and scavenger receptor A but upregulates LOX-1 in human macrophages. Am J Physiol Heart Circ Physiol 278: 1042-1048, 2000.
    • (2000) Am J Physiol Heart Circ Physiol , vol.278 , pp. 1042-1048
    • Draude, G.1    Lorenz, R.L.2
  • 53
    • 38749118269 scopus 로고    scopus 로고
    • The lectin-like oxidized low-density-lipoprotein receptor: A pro-inflammatory factor in vascular disease
    • Dunn S, Vohra RS, Murphy JE, Homer-Vanniasinkam S, Walker JH, and Ponnambalam S. The lectin-like oxidized low-density-lipoprotein receptor: a pro-inflammatory factor in vascular disease. Biochem J 409: 349-355, 2008.
    • (2008) Biochem J , vol.409 , pp. 349-355
    • Dunn, S.1    Vohra, R.S.2    Murphy, J.E.3    Homer-Vanniasinkam, S.4    Walker, J.H.5    Ponnambalam, S.6
  • 54
    • 0032921371 scopus 로고    scopus 로고
    • Formation of 4-hydroxy-2-nonenal-modified proteins in ischemic rat heart
    • Eaton P, Li JM, Hearse DJ, and Shattock MJ. Formation of 4-hydroxy-2-nonenal-modified proteins in ischemic rat heart. Am J Physiol 276: 935-943, 1999.
    • (1999) Am J Physiol , vol.276 , pp. 935-943
    • Eaton, P.1    Li, J.M.2    Hearse, D.J.3    Shattock, M.J.4
  • 55
    • 0028330345 scopus 로고
    • Accelerated in vitro apoptosys of lymphocytes from patients with systemic lupus erythematosus
    • Emlen W, Niebur J, and Kadera R. Accelerated in vitro apoptosys of lymphocytes from patients with systemic lupus erythematosus. J Immunol 152: 3685-3692, 1994.
    • (1994) J Immunol , vol.152 , pp. 3685-3692
    • Emlen, W.1    Niebur, J.2    Kadera, R.3
  • 57
    • 0025814980 scopus 로고
    • Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes
    • Esterbauer H, Schaur RJ, and Zollner H. Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes. Free Radic Biol Med 11: 81-128, 1991.
    • (1991) Free Radic Biol Med , vol.11 , pp. 81-128
    • Esterbauer, H.1    Schaur, R.J.2    Zollner, H.3
  • 58
    • 84867891120 scopus 로고    scopus 로고
    • Physicochemical and immunological studies on 4-hydroxynonenal modified HSA: Implications of protein damage by lipid peroxidation products in the etiopathogenesisi of SLE
    • Farzana Khatoon M and Khursheed Alam AA. Physicochemical and immunological studies on 4-hydroxynonenal modified HSA: implications of protein damage by lipid peroxidation products in the etiopathogenesisi of SLE. Hum Immunol 73: 1132-1139, 2012.
    • (2012) Hum Immunol , vol.73 , pp. 1132-1139
    • Farzana Khatoon, M.1    Khursheed Alam, A.A.2
  • 62
    • 0032833569 scopus 로고    scopus 로고
    • Keratinocytes form patients with lupus erythematosus show enhanced cytotoxicity to ultraviolet radiation and to antibody-mediated cytotoxicity
    • Furukawa F, Itoh T, Wakita H, Yagi H, Tokura Y, Norris DA, and Takigawa M. Keratinocytes form patients with lupus erythematosus show enhanced cytotoxicity to ultraviolet radiation and to antibody-mediated cytotoxicity. Clin Exp Immunol 118: 164-170, 1999.
    • (1999) Clin Exp Immunol , vol.118 , pp. 164-170
    • Furukawa, F.1    Itoh, T.2    Wakita, H.3    Yagi, H.4    Tokura, Y.5    Norris, D.A.6    Takigawa, M.7
  • 63
    • 84903270398 scopus 로고    scopus 로고
    • Oxidative damage and the Nrf2- ARE pathway in neurodegenerative diseases
    • Gan L and Johnson JA. Oxidative damage and the Nrf2- ARE pathway in neurodegenerative diseases. Biochim Biophys Acta 1842: 1208-1218, 2014.
    • (2014) Biochim Biophys Acta , vol.1842 , pp. 1208-1218
    • Gan, L.1    Johnson, J.A.2
  • 65
    • 0030778080 scopus 로고    scopus 로고
    • Interleukin-10 promotes activation-induced cell death of SLE lymphocytes mediated by Fas ligand
    • Georgescu L, Vakkalanka RK, Elkon KB, and Crow MK. Interleukin-10 promotes activation-induced cell death of SLE lymphocytes mediated by Fas ligand. J Clin Invest 100: 2622-2633, 1997.
    • (1997) J Clin Invest , vol.100 , pp. 2622-2633
    • Georgescu, L.1    Vakkalanka, R.K.2    Elkon, K.B.3    Crow, M.K.4
  • 66
    • 84892163616 scopus 로고    scopus 로고
    • Autophagy as an essential cellular antioxidant pathway in neurodegenerative disease
    • Giordano S, Darley-Usmar V, and Zhang J. Autophagy as an essential cellular antioxidant pathway in neurodegenerative disease. Redox Biol 2: 82-90, 2013.
    • (2013) Redox Biol , vol.2 , pp. 82-90
    • Giordano, S.1    Darley-Usmar, V.2    Zhang, J.3
  • 67
    • 63849244747 scopus 로고    scopus 로고
    • Increased oxidation of certain glycolysis and energy metabolism enzymes in the frontal cortex in Lewy body diseases
    • Gómez A and Ferrer I. Increased oxidation of certain glycolysis and energy metabolism enzymes in the frontal cortex in Lewy body diseases. J Neurosci Res 87: 1002-1013, 2009.
    • (2009) J Neurosci Res , vol.87 , pp. 1002-1013
    • Gómez, A.1    Ferrer, I.2
  • 69
    • 80052743099 scopus 로고    scopus 로고
    • The autoimmune concept of atherosclerosis
    • Grundtman C and Wick G. The autoimmune concept of atherosclerosis. Curr Opin Lipidol 22: 327-334, 2011.
    • (2011) Curr Opin Lipidol , vol.22 , pp. 327-334
    • Grundtman, C.1    Wick, G.2
  • 70
    • 0027480960 scopus 로고
    • A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes. the Huntington's Disease Collaborative Research Group
    • H.s.D.C.R. Group. A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes. The Huntington's Disease Collaborative Research Group. Cell 72: 971-983, 1993.
    • (1993) Cell , vol.72 , pp. 971-983
  • 71
    • 84878772042 scopus 로고    scopus 로고
    • Oxidized lipids activate autophagy in a JNK-dependent manner by stimulating the endoplasmic reticulum stress response
    • Haberzett P and Hill BG. Oxidized lipids activate autophagy in a JNK-dependent manner by stimulating the endoplasmic reticulum stress response. Redox Biol 1: 56-64, 2013.
    • (2013) Redox Biol , vol.1 , pp. 56-64
    • Haberzett, P.1    Hill, B.G.2
  • 72
    • 17444442378 scopus 로고    scopus 로고
    • Effect of oxidative stress by iron on 4-hydroxynonenal formation and proliferative activity in hepatomas of different degrees of differentiation
    • Hammer A, Ferro M, Tillian HL Tatzber F, Zollner H, Schauenstein E, and Schaur RJ. Effect of oxidative stress by iron on 4-hydroxynonenal formation and proliferative activity in hepatomas of different degrees of differentiation. Free Radic Biol Med 23: 26-33, 1997.
    • (1997) Free Radic Biol Med , vol.23 , pp. 26-33
    • Hammer, A.1    Ferro, M.2    Zollner, H.3    Schauenstein, E.4    Schaur, R.J.5
  • 73
    • 0037135111 scopus 로고    scopus 로고
    • The amyloid hypothesis of Alzheimer's disease: Progress and problems on the road to therapeutics
    • Hardy J and Selkoe DJ. The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics. Science 297: 353-356, 2002.
    • (2002) Science , vol.297 , pp. 353-356
    • Hardy, J.1    Selkoe, D.J.2
  • 74
    • 0037183928 scopus 로고    scopus 로고
    • Erratum
    • Erratum in: Science 297: 2209, 2002.
    • (2002) Science , vol.297 , pp. 2209
  • 75
    • 0037799214 scopus 로고    scopus 로고
    • Structural basis of protein-bound endogenous aldehydes. Chemical and immunochemical characterization of configurational isomers of a 4-hydroxy-2-nonenalhistidine adduct
    • Hashimoto M, Shibata T, Wasada H, Toyokuni S, and Uchida K. Structural basis of protein-bound endogenous aldehydes. Chemical and immunochemical characterization of configurational isomers of a 4-hydroxy-2-nonenalhistidine adduct. J Biol Chem 278: 5044-5051, 2003.
    • (2003) J Biol Chem , vol.278 , pp. 5044-5051
    • Hashimoto, M.1    Shibata, T.2    Wasada, H.3    Toyokuni, S.4    Uchida, K.5
  • 76
    • 79958282898 scopus 로고    scopus 로고
    • Collapsin response mediator protein-2: An emerging pathologic feature and therapeutic target for neurodisease indications
    • Hensley K, Venkova K, Christov A, Gunning W, and Park J. Collapsin response mediator protein-2: an emerging pathologic feature and therapeutic target for neurodisease indications. Mol Neurobiol 43: 180-191, 2011.
    • (2011) Mol Neurobiol , vol.43 , pp. 180-191
    • Hensley, K.1    Venkova, K.2    Christov, A.3    Gunning, W.4    Park, J.5
  • 77
    • 0032853335 scopus 로고    scopus 로고
    • 4-Hydroxynonenal induces dysfunction and apoptosis of cultured endothelial cells
    • Herbst U, Toborek M, Kaiser S, Mattson MP, and Hennig B. 4-Hydroxynonenal induces dysfunction and apoptosis of cultured endothelial cells. J Cell Physiol 181: 295-303, 1999.
    • (1999) J Cell Physiol , vol.181 , pp. 295-303
    • Herbst, U.1    Toborek, M.2    Kaiser, S.3    Mattson, M.P.4    Hennig, B.5
  • 78
    • 41149116150 scopus 로고    scopus 로고
    • Unsaturated lipid peroxidation-derived aldehydes activate autophagy in vascular smooth-muscle cells
    • Hill BG, Haberzettl P, Ahmed Y, Srivastava S, and Bhatnagar A. Unsaturated lipid peroxidation-derived aldehydes activate autophagy in vascular smooth-muscle cells. Biochem J 410: 525-534, 2008.
    • (2008) Biochem J , vol.410 , pp. 525-534
    • Hill, B.G.1    Haberzettl, P.2    Ahmed, Y.3    Srivastava, S.4    Bhatnagar, A.5
  • 80
    • 0027212751 scopus 로고
    • Modification of LDL with 4- hydroxynonenal and malondialdehyde as a model for soluble oxidized LDL
    • Hoff HF and O'Neil JA. Modification of LDL with 4- hydroxynonenal and malondialdehyde as a model for soluble oxidized LDL. J Lipid Res 34: 1209-1217, 1993.
    • (1993) J Lipid Res , vol.34 , pp. 1209-1217
    • Hoff, H.F.1    O'Neil, J.A.2
  • 82
    • 0037329336 scopus 로고    scopus 로고
    • Phospholipid hydroxyalkenals. Biological and chemical properties of specific oxidized lipids present in atherosclerotic lesions
    • Hoff HF, O'Neil J, Wu Z, Hoppe G, and Salomon RL. Phospholipid hydroxyalkenals. Biological and chemical properties of specific oxidized lipids present in atherosclerotic lesions. Arterioscler Thromb Vasc Biol 23: 275-282, 2003.
    • (2003) Arterioscler Thromb Vasc Biol , vol.23 , pp. 275-282
    • Hoff, H.F.1    O'Neil, J.2    Wu, Z.3    Hoppe, G.4    Salomon, R.L.5
  • 83
    • 0031004323 scopus 로고    scopus 로고
    • Human anti-Ro autoantibodies bind multiple conformational epitopes of 60-kD Ro autoantigen
    • Huang SC, Scofield RH, Kurien BT, and Harley JB. Human anti-Ro autoantibodies bind multiple conformational epitopes of 60-kD Ro autoantigen. J Clin Immunol 17: 212-219, 1997.
    • (1997) J Clin Immunol , vol.17 , pp. 212-219
    • Huang, S.C.1    Scofield, R.H.2    Kurien, B.T.3    Harley, J.B.4
  • 85
    • 33847757480 scopus 로고    scopus 로고
    • Elevated oxidative stress in erythrocytes due to an SOD1 deficiency causes anemia and triggers autoantibody production
    • Iuchi Y, Okada F, Onuma K, Onoda T, Asao H, Kobayashi M, and Fujii J. Elevated oxidative stress in erythrocytes due to an SOD1 deficiency causes anemia and triggers autoantibody production. Biochem J 402: 219-227, 2007.
    • (2007) Biochem J , vol.402 , pp. 219-227
    • Iuchi, Y.1    Okada, F.2    Onuma, K.3    Onoda, T.4    Asao, H.5    Kobayashi, M.6    Fujii, J.7
  • 87
    • 0035947678 scopus 로고    scopus 로고
    • IkappaB kinase a molecular target for inhibition by 4-hydroxy-2-nonenal
    • Ji C, Kozak KR, and Marnett LJ. IkappaB kinase, a molecular target for inhibition by 4-hydroxy-2-nonenal. J Biol Chem 276: 18223-18228, 2001.
    • (2001) J Biol Chem , vol.276 , pp. 18223-18228
    • Ji, C.1    Kozak, K.R.2    Marnett, L.J.3
  • 88
    • 84884904263 scopus 로고    scopus 로고
    • PGC-1a, mitochondrial dysfunction, and Huntington's disease
    • Johri A, Chandra A, and Beal MF. PGC-1a, mitochondrial dysfunction, and Huntington's disease. Free Radic Biol Med 62: 37-46, 2013.
    • (2013) Free Radic Biol Med , vol.62 , pp. 37-46
    • Johri, A.1    Chandra, A.2    Beal, M.F.3
  • 89
    • 84878692259 scopus 로고    scopus 로고
    • Enhanced 4-hydroxynonenal resistance in KEAP1 silenced human colon cancer cells
    • Jung KA and Kwak MK. Enhanced 4-hydroxynonenal resistance in KEAP1 silenced human colon cancer cells. Oxid Med Cell Longev 2013: 423965, 2013.
    • (2013) Oxid Med Cell Longev , vol.2013
    • Jung, K.A.1    Kwak, M.K.2
  • 90
    • 76349092912 scopus 로고    scopus 로고
    • Distribution of 4-hydroxynonenal-protein conjugates as a marker of lipid peroxidation and parameter of malignancy in astrocytic and ependymal tumors of the brain
    • Juric-Sekhar G, Zarkovic K, Waeg G, Cipak A, and Zarkovic N. Distribution of 4-hydroxynonenal-protein conjugates as a marker of lipid peroxidation and parameter of malignancy in astrocytic and ependymal tumors of the brain. Tumori 95: 762-768, 2009.
    • (2009) Tumori , vol.95 , pp. 762-768
    • Juric-Sekhar, G.1    Zarkovic, K.2    Waeg, G.3    Cipak, A.4    Zarkovic, N.5
  • 91
    • 0034602694 scopus 로고    scopus 로고
    • A plateletendothelium interaction mediated by lectin-like oxidized low-density lipoprotein receptor-1
    • Kakutani M, Masaki T, and Sawamura T. A plateletendothelium interaction mediated by lectin-like oxidized low-density lipoprotein receptor-1. Proc Natl Acad Sci U S A 97: 360-364, 2000.
    • (2000) Proc Natl Acad Sci U S A , vol.97 , pp. 360-364
    • Kakutani, M.1    Masaki, T.2    Sawamura, T.3
  • 92
    • 0033600604 scopus 로고    scopus 로고
    • The beginning of the end: IkappaB kinase (IKK) and NF-kappaB activation
    • Karin M. The beginning of the end: IkappaB kinase (IKK) and NF-kappaB activation. J Biol Chem 274: 27339-27342, 1999.
    • (1999) J Biol Chem , vol.274 , pp. 27339-27342
    • Karin, M.1
  • 94
    • 0031472489 scopus 로고    scopus 로고
    • (Carboxyalkyl) pyrroles in human plasma and oxidized low-density lipoproteins
    • Kaur K, Salomon RG, O'Neil J, and Hoff HF. (Carboxyalkyl)pyrroles in human plasma and oxidized low-density lipoproteins. Chem Res Toxicol 10: 1387-1396, 1997.
    • (1997) Chem Res Toxicol , vol.10 , pp. 1387-1396
    • Kaur, K.1    Salomon, R.G.2    O'Neil, J.3    Hoff, H.F.4
  • 96
    • 0141992044 scopus 로고    scopus 로고
    • Role of nuclear receptors in the regulation of gene expression by dietary fatty acids
    • Khan SA and Vanden Heuvel JP. Role of nuclear receptors in the regulation of gene expression by dietary fatty acids. J Nutr Biochem 14: 554-567, 2003.
    • (2003) J Nutr Biochem , vol.14 , pp. 554-567
    • Khan, S.A.1    Vanden Heuvel, J.P.2
  • 97
    • 0027755138 scopus 로고
    • Immunology of atherosclerosis. Demonstration of heat shock protein 60 expression and T lymphocytes bearing alpha/beta or gamma/delta receptor in human atherosclerotic lesions
    • Kleindienst R, Xu Q, Willeit J, Waldenberger FR, Weimann S, and Wick G. Immunology of atherosclerosis. Demonstration of heat shock protein 60 expression and T lymphocytes bearing alpha/beta or gamma/delta receptor in human atherosclerotic lesions. Am J Pathol 142: 1927- 1937, 1993.
    • (1993) Am J Pathol , vol.142 , pp. 1927-1937
    • Kleindienst, R.1    Xu, Q.2    Willeit, J.3    Waldenberger, F.R.4    Weimann, S.5    Wick, G.6
  • 98
    • 25444446818 scopus 로고    scopus 로고
    • Anti-HSP60 immunity is already associated with atherosclerosis early in life
    • Knoflach M, Bernhard D, and Wick G. Anti-HSP60 immunity is already associated with atherosclerosis early in life. Ann N Y Acad Sci 1051: 323-331, 2005.
    • (2005) Ann N y Acad Sci , vol.1051 , pp. 323-331
    • Knoflach, M.1    Bernhard, D.2    Wick, G.3
  • 100
    • 0029866196 scopus 로고    scopus 로고
    • 4-Hydroxyhexenal is a potent inducer of the mitochondrial permeability transition
    • Kristal BS, Park BK, and Yu BP. 4-Hydroxyhexenal is a potent inducer of the mitochondrial permeability transition. J Biol Chem 271: 6033-6038, 1996.
    • (1996) J Biol Chem , vol.271 , pp. 6033-6038
    • Kristal, B.S.1    Park, B.K.2    Yu, B.P.3
  • 102
    • 0034044633 scopus 로고    scopus 로고
    • Inducible expression of LOX-1, a novel receptor for oxidized LDL, in macrophages and vascular smooth muscle cells
    • Kume N, Moriwaki H, Kataoka H, Minami M, Murase T, Sawamura T, Masaki T, and Kita T. Inducible expression of LOX-1, a novel receptor for oxidized LDL, in macrophages and vascular smooth muscle cells. Ann N Y Acad Sci 902: 323-327, 2000.
    • (2000) Ann N y Acad Sci , vol.902 , pp. 323-327
    • Kume, N.1    Moriwaki, H.2    Kataoka, H.3    Minami, M.4    Murase, T.5    Sawamura, T.6    Masaki, T.7    Kita, T.8
  • 103
    • 0346037268 scopus 로고    scopus 로고
    • Scavenger receptors class A-I/II and CD36 are the principal receptors responsible for the uptake of modified low density lipoprotein leading to lipid loading in macrophages
    • Kunjathoor VV, Febbraio M, Podrez EA, Moore KJ, Andersson L, Koehn S, Rhee JS, Silverstein R, Hoff HF, and Freeman MW. Scavenger receptors class A-I/II and CD36 are the principal receptors responsible for the uptake of modified low density lipoprotein leading to lipid loading in macrophages. J Biol Chem 277: 49982-49988, 2002.
    • (2002) J Biol Chem , vol.277 , pp. 49982-49988
    • Kunjathoor, V.V.1    Febbraio, M.2    Podrez, E.A.3    Moore, K.J.4    Andersson, L.5    Koehn, S.6    Rhee, J.S.7    Silverstein, R.8    Hoff, H.F.9    Freeman, M.W.10
  • 104
    • 84858336640 scopus 로고    scopus 로고
    • Putative sequences on Ro60 three-dimensional structure accessible for 4-hydroxy-2-nonenal (HNE) modification compared to in vitro HNE modification of Ro60 sequences
    • Kurien BT, D'Souza A, Terzyan S, and Scofield RH. Putative sequences on Ro60 three-dimensional structure accessible for 4-hydroxy-2-nonenal (HNE) modification compared to in vitro HNE modification of Ro60 sequences. Mol Immunol 50: 185-192, 2012.
    • (2012) Mol Immunol , vol.50 , pp. 185-192
    • Kurien, B.T.1    D'Souza, A.2    Terzyan, S.3    Scofield, R.H.4
  • 107
    • 33747030602 scopus 로고    scopus 로고
    • Autoantibody determination in the diagnosis of systemic lupus erythematosus
    • Kurien BT and Scofield RH. Autoantibody determination in the diagnosis of systemic lupus erythematosus. Scand J Immunol 64: 227-235, 2006.
    • (2006) Scand J Immunol , vol.64 , pp. 227-235
    • Kurien, B.T.1    Scofield, R.H.2
  • 108
    • 33646569106 scopus 로고    scopus 로고
    • Lipid peroxidation in systemic lupus erythematosus
    • Kurien BT and Scofield RH. Lipid peroxidation in systemic lupus erythematosus. Indian J Exp Biol 44: 349-356, 2006.
    • (2006) Indian J Exp Biol , vol.44 , pp. 349-356
    • Kurien, B.T.1    Scofield, R.H.2
  • 109
    • 50949098933 scopus 로고    scopus 로고
    • Autoimmunity and oxidatively modified autoantigens
    • Kurien BT and Scofield RH. Autoimmunity and oxidatively modified autoantigens. Autoimmunity Rev 7: 567-573, 2008.
    • (2008) Autoimmunity Rev , vol.7 , pp. 567-573
    • Kurien, B.T.1    Scofield, R.H.2
  • 110
    • 33644637265 scopus 로고    scopus 로고
    • Decreased complex II respiration and HNE-modified SDH subunit in diabetic heart
    • Lashin OM, Szweda PA, Szweda LI, and Romani AM. Decreased complex II respiration and HNE-modified SDH subunit in diabetic heart. Free Radic Biol Med 40: 886-896, 2006.
    • (2006) Free Radic Biol Med , vol.40 , pp. 886-896
    • Lashin, O.M.1    Szweda, P.A.2    Szweda, L.I.3    Romani, A.M.4
  • 111
  • 112
    • 0024475227 scopus 로고
    • NF-kappa B: A pleiotropic mediator of inducible and tissue-specific gene control
    • Lenardo MJ and Baltimore D. NF-kappa B: a pleiotropic mediator of inducible and tissue-specific gene control. Cell 58: 227-229, 1989.
    • (1989) Cell , vol.58 , pp. 227-229
    • Lenardo, M.J.1    Baltimore, D.2
  • 113
    • 28444442268 scopus 로고    scopus 로고
    • 4-Hydroxynonenal and cholesterol oxidation products in atherosclerosis
    • Leonarduzzi G, Chiarpotto E, Biasi F, and Poli G. 4-Hydroxynonenal and cholesterol oxidation products in atherosclerosis. Mol Nutr Food Res 49: 1044-1049, 2005.
    • (2005) Mol Nutr Food Res , vol.49 , pp. 1044-1049
    • Leonarduzzi, G.1    Chiarpotto, E.2    Biasi, F.3    Poli, G.4
  • 114
    • 0030820474 scopus 로고    scopus 로고
    • Acetaldehyde- modified and 4-hydroxynonenal-modified proteins in the livers of rats with alcoholic liver disease
    • Li CJ, Nanji AA, Siakotos AN, and Lin RC. Acetaldehyde- modified and 4-hydroxynonenal-modified proteins in the livers of rats with alcoholic liver disease. Hepatology 26: 650-657, 1997.
    • (1997) Hepatology , vol.26 , pp. 650-657
    • Li, C.J.1    Nanji, A.A.2    Siakotos, A.N.3    Lin, R.C.4
  • 115
    • 0036076620 scopus 로고    scopus 로고
    • Statins modulate oxidized low-density lipoprotein- mediated adhesion molecule expression in human coronary artery endothelial cells: Role of LOX-1
    • Li D, Chen H, Romeo F, Sawamura T, Saldeen T, and Mehta JL. Statins modulate oxidized low-density lipoprotein- mediated adhesion molecule expression in human coronary artery endothelial cells: role of LOX-1. J Pharmacol Exp Ther 302: 601-605, 2002.
    • (2002) J Pharmacol Exp Ther , vol.302 , pp. 601-605
    • Li, D.1    Chen, H.2    Romeo, F.3    Sawamura, T.4    Saldeen, T.5    Mehta, J.L.6
  • 116
    • 0034720846 scopus 로고    scopus 로고
    • Antisense to LOX-1 inhibits oxidized LDL-mediated upregulation of monocyte chemoattractant protein-1 and monocyte adhesion to human coronary artery endothelial cells
    • Li D and Mehta JL. Antisense to LOX-1 inhibits oxidized LDL-mediated upregulation of monocyte chemoattractant protein-1 and monocyte adhesion to human coronary artery endothelial cells. Circulation 101: 2889-2895, 2000.
    • (2000) Circulation , vol.101 , pp. 2889-2895
    • Li, D.1    Mehta, J.L.2
  • 117
    • 0034118056 scopus 로고    scopus 로고
    • Upregulation of endothelial receptor for oxidized LDL (LOX-1) by oxidized LDL and implications in apoptosis of human coronary artery endothelial cells: Evidence from use of antisense LOX-1 mRNA and chemical inhibitors
    • Li D and Mehta JL. Upregulation of endothelial receptor for oxidized LDL (LOX-1) by oxidized LDL and implications in apoptosis of human coronary artery endothelial cells: evidence from use of antisense LOX-1 mRNA and chemical inhibitors. Arterioscler Thromb Vasc Biol 20: 1116-1122, 2000.
    • (2000) Arterioscler Thromb Vasc Biol , vol.20 , pp. 1116-1122
    • Li, D.1    Mehta, J.L.2
  • 119
    • 0021950853 scopus 로고
    • 4-Hydroxy-2-enals are substrates for glutathione transferase
    • Lin P, Danielson H, and Mannervik B. 4-Hydroxy-2-enals are substrates for glutathione transferase. FEBS Lett 179: 267-270, 1985.
    • (1985) FEBS Lett , vol.179 , pp. 267-270
    • Lin, P.1    Danielson, H.2    Mannervik, B.3
  • 120
    • 0032780007 scopus 로고    scopus 로고
    • 4-Hydroxynonenal triggers an epidermal growth factor receptorlinked signal pathway for growth inhibition
    • Liu W, Akhand AA, Kato M, Yokoyama I, Miyata T, Kurokawa K, Uchida K, and Nakashima I. 4-Hydroxynonenal triggers an epidermal growth factor receptorlinked signal pathway for growth inhibition. J Cell Sci 112: 2409-2417, 1999.
    • (1999) J Cell Sci , vol.112 , pp. 2409-2417
    • Liu, W.1    Akhand, A.A.2    Kato, M.3    Yokoyama, I.4    Miyata, T.5    Kurokawa, K.6    Uchida, K.7    Nakashima, I.8
  • 121
    • 1842293994 scopus 로고    scopus 로고
    • High-affinity saturable uptake of oxidized low density lipoprotein by macrophages from mice lacking the scavenger receptor class A type I/I
    • Lougheed M, Ming Lum C, Ling W, Suzuki H, Kodama T, and Steinbrecher UP. High-affinity saturable uptake of oxidized low density lipoprotein by macrophages from mice lacking the scavenger receptor class A type I/I. J Biol Chem 272: 12938-12944, 1997.
    • (1997) J Biol Chem , vol.272 , pp. 12938-12944
    • Lougheed, M.1    Ming Lum, C.2    Ling, W.3    Suzuki, H.4    Kodama, T.5    Steinbrecher, U.P.6
  • 122
    • 0034648768 scopus 로고    scopus 로고
    • Atherosclerosis
    • Lusis AJ. Atherosclerosis. Nature 407: 233-241, 2000.
    • (2000) Nature , vol.407 , pp. 233-241
    • Lusis, A.J.1
  • 123
    • 84899667648 scopus 로고    scopus 로고
    • Impairment of aldehyde dehydrogenase-2 by 4-hydroxy-2-nonenal adduct formation and cardiomyocyte hypertrophy in mice fed a high-fat diet and injected with low-dose streptozotocin
    • Mali VR, Ning R, Chen J, Yang XP, Xu J, and Palaniyandi SS. Impairment of aldehyde dehydrogenase-2 by 4-hydroxy-2-nonenal adduct formation and cardiomyocyte hypertrophy in mice fed a high-fat diet and injected with low-dose streptozotocin. Exp Biol Med 239: 610- 618, 2014.
    • (2014) Exp Biol Med , vol.239 , pp. 610-618
    • Mali, V.R.1    Ning, R.2    Chen, J.3    Yang, X.P.4    Xu, J.5    Palaniyandi, S.S.6
  • 124
    • 70450137050 scopus 로고    scopus 로고
    • The hemeoxygenase/biliverdin reductase pathway in drug research and development
    • Mancuso C and Barone E. The hemeoxygenase/biliverdin reductase pathway in drug research and development. Curr Drug Metab 10: 579-594, 2009.
    • (2009) Curr Drug Metab , vol.10 , pp. 579-594
    • Mancuso, C.1    Barone, E.2
  • 125
    • 1442323800 scopus 로고    scopus 로고
    • Autoimmunity to heat shock proteins in atherosclerosis
    • Mandal K, Jahangiri M, and Xu Q. Autoimmunity to heat shock proteins in atherosclerosis. Autoimmun Rev 3: 31-37, 2004.
    • (2004) Autoimmun Rev , vol.3 , pp. 31-37
    • Mandal, K.1    Jahangiri, M.2    Xu, Q.3
  • 126
    • 0031020993 scopus 로고    scopus 로고
    • Amyloid beta-peptide impairs glucose transport in hippocampal and cortical neurons: Involvement of membrane lipid peroxidation
    • Mark RJ, Pang Z, Geddes JW, Uchida K, and Mattson MP. Amyloid beta-peptide impairs glucose transport in hippocampal and cortical neurons: involvement of membrane lipid peroxidation. J Neurosci 17: 1046-1054, 1997.
    • (1997) J Neurosci , vol.17 , pp. 1046-1054
    • Mark, R.J.1    Pang, Z.2    Geddes, J.W.3    Uchida, K.4    Mattson, M.P.5
  • 127
    • 75949083202 scopus 로고    scopus 로고
    • Protein targets of oxidative damage in human neurodegenerative diseases with abnormal protein aggregates
    • Martínez A, Portero-Otin M, Pamplona R, and Ferrer I. Protein targets of oxidative damage in human neurodegenerative diseases with abnormal protein aggregates. Brain Pathol 20: 281-297, 2010.
    • (2010) Brain Pathol , vol.20 , pp. 281-297
    • Martínez, A.1    Portero-Otin, M.2    Pamplona, R.3    Ferrer, I.4
  • 128
    • 0037470807 scopus 로고    scopus 로고
    • NF-kappa B activation in endothelial cells treated with oxidized high-density lipoprotein
    • Matsunaga T, Hokari S, Koyama I, Harada T, and Komoda T. NF-kappa B activation in endothelial cells treated with oxidized high-density lipoprotein. Biochem Biophys Res Commun 303: 313-319, 2003.
    • (2003) Biochem Biophys Res Commun , vol.303 , pp. 313-319
    • Matsunaga, T.1    Hokari, S.2    Koyama, I.3    Harada, T.4    Komoda, T.5
  • 129
  • 130
    • 0036181860 scopus 로고    scopus 로고
    • Early inflammatory- immunological lesions in juvenile atherosclerosis from the Pathobiological Determinants of Atherosclerosis in Youth (PDAY)-study
    • Millonig G, Malcom GT, and Wick G. Early inflammatory- immunological lesions in juvenile atherosclerosis from the Pathobiological Determinants of Atherosclerosis in Youth (PDAY)-study. Atherosclerosis 160: 441-448, 2002.
    • (2002) Atherosclerosis , vol.160 , pp. 441-448
    • Millonig, G.1    Malcom, G.T.2    Wick, G.3
  • 131
    • 0034327194 scopus 로고    scopus 로고
    • Anti-SSA/Ro and anti-SSB/La autoantibodies bind the surface of apoptotic fetal cardiocytes and promote secretion of TNF-a by macrophages
    • Miranda-Carús M-E, Askanase AD, Clancy RM, Di Donato F, Chou T-M, Libera MR, Chan EKL, and Buyon JP. Anti-SSA/Ro and anti-SSB/La autoantibodies bind the surface of apoptotic fetal cardiocytes and promote secretion of TNF-a by macrophages. J Immunol 165: 5345-5351, 2000.
    • (2000) J Immunol , vol.165 , pp. 5345-5351
    • Miranda-Carús, M.-E.1    Askanase, A.D.2    Clancy, R.M.3    Di Donato, F.4    Chou, T.-M.5    Libera, M.R.6    Chan, E.K.L.7    Buyon, J.P.8
  • 132
    • 84890507960 scopus 로고    scopus 로고
    • Modification and functional inhibition of regulator of G-protein signaling 4 (RGS4) by 4-hydroxy-2-nonenal
    • Monroy CA, Doorn JA, and Roman DL. Modification and functional inhibition of regulator of G-protein signaling 4 (RGS4) by 4-hydroxy-2-nonenal. Chem Res Toxicol 26: 1832-1839, 2013.
    • (2013) Chem Res Toxicol , vol.26 , pp. 1832-1839
    • Monroy, C.A.1    Doorn, J.A.2    Roman, D.L.3
  • 135
    • 0028897831 scopus 로고
    • Structural definition of early lysine and histidine adduction chemistry of 4-hydroxynonenal
    • Nadkarni DV and Sayre LM. Structural definition of early lysine and histidine adduction chemistry of 4-hydroxynonenal. Chem Res Toxicol 8: 284-291, 1995.
    • (1995) Chem Res Toxicol , vol.8 , pp. 284-291
    • Nadkarni, D.V.1    Sayre, L.M.2
  • 136
    • 37849013375 scopus 로고    scopus 로고
    • Advanced lipid peroxidation end products in oxidative damage to proteins. Potential role in diseases and therapeutic prospects for the inhibitors
    • Negre-Salvayre A, Coatrieux C, Ingueneau C, and Salvayre R. Advanced lipid peroxidation end products in oxidative damage to proteins. Potential role in diseases and therapeutic prospects for the inhibitors. Br J Pharmacol 153: 6-20, 2008.
    • (2008) Br J Pharmacol , vol.153 , pp. 6-20
    • Negre-Salvayre, A.1    Coatrieux, C.2    Ingueneau, C.3    Salvayre, R.4
  • 139
    • 0032867803 scopus 로고    scopus 로고
    • Localization of hydroxynonenal protein adducts in normal human kidney and selected human kidney cancers
    • Oberley TD, Toyokuni S, and Szweda LI. Localization of hydroxynonenal protein adducts in normal human kidney and selected human kidney cancers. Free Radic Biol Med 27: 695-703, 1999.
    • (1999) Free Radic Biol Med , vol.27 , pp. 695-703
    • Oberley, T.D.1    Toyokuni, S.2    Szweda, L.I.3
  • 141
    • 0032482958 scopus 로고    scopus 로고
    • Lectin-like oxidized low-density lipoprotein receptor 1 mediates phagocytosis of aged/apoptotic cells in endothelial cells
    • Oka K, Sawamura T, Kikuta K, Itokawa S, Kume N, Kita T, and Masaki T. Lectin-like oxidized low-density lipoprotein receptor 1 mediates phagocytosis of aged/apoptotic cells in endothelial cells. Proc Natl Acad Sci U S A 95: 9535-9540, 1998.
    • (1998) Proc Natl Acad Sci U S A , vol.95 , pp. 9535-9540
    • Oka, K.1    Sawamura, T.2    Kikuta, K.3    Itokawa, S.4    Kume, N.5    Kita, T.6    Masaki, T.7
  • 142
    • 78049386757 scopus 로고    scopus 로고
    • Oxidative modification to LDL receptor-related protein 1 in hippocampus from subjects with Alzheimer disease: Implications for Ab accumulation in AD brain
    • Owen JB, Sultana R, Aluise CD, Erickson MA, Price TO, Bu G, Banks WA, and Butterfield DA. Oxidative modification to LDL receptor-related protein 1 in hippocampus from subjects with Alzheimer disease: implications for Ab accumulation in AD brain. Free Radic Biol Med 49: 1798-1803, 2010.
    • (2010) Free Radic Biol Med , vol.49 , pp. 1798-1803
    • Owen, J.B.1    Sultana, R.2    Aluise, C.D.3    Erickson, M.A.4    Price, T.O.5    Bu, G.6    Banks, W.A.7    Butterfield, D.A.8
  • 145
    • 0034947535 scopus 로고    scopus 로고
    • Multifunctional alpha-enolase: Its role in diseases
    • Pancholi V. Multifunctional alpha-enolase: its role in diseases. Cell Mol Life Sci 58: 902-920, 2001.
    • (2001) Cell Mol Life Sci , vol.58 , pp. 902-920
    • Pancholi, V.1
  • 146
    • 76349096459 scopus 로고    scopus 로고
    • Resident intimal dendritic cells accumulate lipid and contribute to the initiation of atherosclerosis
    • Paulson KE, Zhu SN, Chen M, Nurmohamed S, Jongstra- Bilen J, and Cybulsky MI. Resident intimal dendritic cells accumulate lipid and contribute to the initiation of atherosclerosis. Circ Res 106: 383-390, 2010.
    • (2010) Circ Res , vol.106 , pp. 383-390
    • Paulson, K.E.1    Zhu, S.N.2    Chen, M.3    Nurmohamed, S.4    Jongstra- Bilen, J.5    Cybulsky, M.I.6
  • 147
    • 0031768026 scopus 로고    scopus 로고
    • Protein modification by the lipid peroxidation product 4-hydroxynonenal in the spinal cords of amyotrophic lateral sclerosis patients
    • Pedersen WA, Fu W, Keller JN, Markesbery WR, Appel S, Smith RG, Kasarskis E, and Mattson MP. Protein modification by the lipid peroxidation product 4-hydroxynonenal in the spinal cords of amyotrophic lateral sclerosis patients. Ann Neurol 44: 819-824, 1998.
    • (1998) Ann Neurol , vol.44 , pp. 819-824
    • Pedersen, W.A.1    Fu, W.2    Keller, J.N.3    Markesbery, W.R.4    Appel, S.5    Smith, R.G.6    Kasarskis, E.7    Mattson, M.P.8
  • 148
    • 84855583479 scopus 로고    scopus 로고
    • Oxidative stress and Down syndrome: A route toward Alzheimer-like dementia
    • Perluigi M and Butterfield DA. Oxidative stress and Down syndrome: a route toward Alzheimer-like dementia. Curr Gerontol Geriatr Res 2012: 724904, 2012.
    • (2012) Curr Gerontol Geriatr Res , vol.2012
    • Perluigi, M.1    Butterfield, D.A.2
  • 150
    • 70350089195 scopus 로고    scopus 로고
    • Redox proteomics identification of 4-hydroxynonenal-modified brain proteins in Alzheimer's disease: Role of lipid peroxidation in Alzheimer's disease pathogenesis
    • Perluigi M, Sultana R, Cenini G, Di Domenico F, Memo M, Pierce WM, Coccia R, and Butterfield DA. Redox proteomics identification of 4-hydroxynonenal-modified brain proteins in Alzheimer's disease: role of lipid peroxidation in Alzheimer's disease pathogenesis. Proteomics Clin Appl 3: 682-693, 2009.
    • (2009) Proteomics Clin Appl , vol.3 , pp. 682-693
    • Perluigi, M.1    Sultana, R.2    Cenini, G.3    Di Domenico, F.4    Memo, M.5    Pierce, W.M.6    Coccia, R.7    Butterfield, D.A.8
  • 151
    • 4444314070 scopus 로고    scopus 로고
    • Reactions of 4-hydroxynonenal with proteins and cellular targets
    • Petersen DR and Doorn JA. Reactions of 4-hydroxynonenal with proteins and cellular targets. Free Radic Biol Med 37: 937-945, 2004.
    • (2004) Free Radic Biol Med , vol.37 , pp. 937-945
    • Petersen, D.R.1    Doorn, J.A.2
  • 154
    • 0036468883 scopus 로고    scopus 로고
    • Synergistic effect of 4-hydroxynonenal and PPAR ligands in controlling human leukemic cell growth and differentiation
    • Pizzimenti S, Laurora S, Briatore F, Ferretti C, Dianzani MU, and Barrera G. Synergistic effect of 4-hydroxynonenal and PPAR ligands in controlling human leukemic cell growth and differentiation. Free Radic Biol Med 32: 233-245, 2002.
    • (2002) Free Radic Biol Med , vol.32 , pp. 233-245
    • Pizzimenti, S.1    Laurora, S.2    Briatore, F.3    Ferretti, C.4    Dianzani, M.U.5    Barrera, G.6
  • 155
    • 79952275493 scopus 로고    scopus 로고
    • The "two-Faced" effects of reactive oxygen species and the lipid peroxidation product 4-hydroxynonenal in the hallmarks of cancer
    • Pizzimenti S, Toaldo C, Pettazzoni P, Dianzani MU, and Barrera G. The "Two-Faced" effects of reactive oxygen species and the lipid peroxidation product 4-hydroxynonenal in the hallmarks of cancer. Cancers 2: 338- 363, 2010.
    • (2010) Cancers , vol.2 , pp. 338-363
    • Pizzimenti, S.1    Toaldo, C.2    Pettazzoni, P.3    Dianzani, M.U.4    Barrera, G.5
  • 156
    • 0018778353 scopus 로고
    • Lipid peroxidation of the microsomal fraction and extracted microsomal lipids from DAB-induced hepatomas
    • Player TJ, Mills DJ, and Horton AA. Lipid peroxidation of the microsomal fraction and extracted microsomal lipids from DAB-induced hepatomas. Br J Cancer 39: 773-778, 1979.
    • (1979) Br J Cancer , vol.39 , pp. 773-778
    • Player, T.J.1    Mills, D.J.2    Horton, A.A.3
  • 157
    • 0037064036 scopus 로고    scopus 로고
    • A novel family of atherogenic oxidized phospholipids promotes macrophage foam cell formation via the scavenger receptor CD36 and is enriched in atherosclerotic lesions
    • Podrez EA, Poliakov E, Shen Z, Zhang R, Deng Y, and Sun M. A novel family of atherogenic oxidized phospholipids promotes macrophage foam cell formation via the scavenger receptor CD36 and is enriched in atherosclerotic lesions. J Biol Chem 277: 38517-38523, 2002.
    • (2002) J Biol Chem , vol.277 , pp. 38517-38523
    • Podrez, E.A.1    Poliakov, E.2    Shen, Z.3    Zhang, R.4    Deng, Y.5    Sun, M.6
  • 159
    • 2442482592 scopus 로고    scopus 로고
    • Free radicals: Key to brain aging and heme oxygenase as a cellular response to oxidative stress
    • Poon HF, Calabrese V, Scapagnini G, and Butterfield DA. Free radicals: key to brain aging and heme oxygenase as a cellular response to oxidative stress. J Gerontol A Biol Sci Med Sci 59: 478-493, 2004.
    • (2004) J Gerontol A Biol Sci Med Sci , vol.59 , pp. 478-493
    • Poon, H.F.1    Calabrese, V.2    Scapagnini, G.3    Butterfield, D.A.4
  • 160
    • 0025285284 scopus 로고
    • Suggested mechanisms for the production of 4-hydroxy-2-nonenal from the autoxidation of polyunsaturated fatty acids
    • Pryor WA and Porter NA. Suggested mechanisms for the production of 4-hydroxy-2-nonenal from the autoxidation of polyunsaturated fatty acids. Free Radic Biol Med 8: 541-543, 1990.
    • (1990) Free Radic Biol Med , vol.8 , pp. 541-543
    • Pryor, W.A.1    Porter, N.A.2
  • 161
    • 34247130917 scopus 로고    scopus 로고
    • Effect of 4-hydroxy-2-nonenal modification on alphasynuclein aggregation
    • Qin Z, Hu D, Han S, Reaney SH, Di Monte DA, and Fink AL. Effect of 4-hydroxy-2-nonenal modification on alphasynuclein aggregation. J Biol Chem 282: 5862-5870, 2007.
    • (2007) J Biol Chem , vol.282 , pp. 5862-5870
    • Qin, Z.1    Hu, D.2    Han, S.3    Reaney, S.H.4    Di Monte, D.A.5    Fink, A.L.6
  • 162
    • 1642292542 scopus 로고    scopus 로고
    • Involvement of collapsin response mediator proteins in the neurite extension induced by neurotrophins in dorsal root ganglion neurons
    • Quach TT, Duchemin AM, Rogemond V, Aguera M, Honnorat J, Belin MF, and Kolattukudy PE. Involvement of collapsin response mediator proteins in the neurite extension induced by neurotrophins in dorsal root ganglion neurons. Mol Cell Neurosci 25: 433-443, 2004.
    • (2004) Mol Cell Neurosci , vol.25 , pp. 433-443
    • Quach, T.T.1    Duchemin, A.M.2    Rogemond, V.3    Aguera, M.4    Honnorat, J.5    Belin, M.F.6    Kolattukudy, P.E.7
  • 163
    • 77957781807 scopus 로고    scopus 로고
    • Collapsin response mediator protein-2 (Crmp2) regulates trafficking by linking endocytic regulatory proteins to dynein motors
    • Rahajeng J, Giridharan SS, Naslavsky N, and Caplan S. Collapsin response mediator protein-2 (Crmp2) regulates trafficking by linking endocytic regulatory proteins to dynein motors. J Biol Chem 285: 31918-31922, 2010.
    • (2010) J Biol Chem , vol.285 , pp. 31918-31922
    • Rahajeng, J.1    Giridharan, S.S.2    Naslavsky, N.3    Caplan, S.4
  • 164
    • 38049054790 scopus 로고    scopus 로고
    • New functions for an iron storage protein: The role of ferritin in immunity and autoimmunity
    • Recalcati S, Invernizzi P, Arosio P, and Cairo G. New functions for an iron storage protein: the role of ferritin in immunity and autoimmunity. J Autoimmun 30: 84-89, 2008.
    • (2008) J Autoimmun , vol.30 , pp. 84-89
    • Recalcati, S.1    Invernizzi, P.2    Arosio, P.3    Cairo, G.4
  • 165
    • 80052261937 scopus 로고    scopus 로고
    • Lipid peroxidation and neurodegenerative disease
    • Reed TT. Lipid peroxidation and neurodegenerative disease. Free Radic Biol Med 51: 1302-1319, 2011.
    • (2011) Free Radic Biol Med , vol.51 , pp. 1302-1319
    • Reed, T.T.1
  • 166
    • 0142072318 scopus 로고    scopus 로고
    • Increased apoptotic neutrophils and macrophages and impaired macrophage phagocytic clearance of apoptotic neutrophils in systemic lupus erythematosus
    • Ren Y, Tang J, Mok MY, Chan AW, Wu A, and Lau CS. Increased apoptotic neutrophils and macrophages and impaired macrophage phagocytic clearance of apoptotic neutrophils in systemic lupus erythematosus. Arthritis Rheum 48: 2888-2897, 2003.
    • (2003) Arthritis Rheum , vol.48 , pp. 2888-2897
    • Ren, Y.1    Tang, J.2    Mok, M.Y.3    Chan, A.W.4    Wu, A.5    Lau, C.S.6
  • 167
    • 0020521409 scopus 로고
    • Lipid peroxidation in hepatomas of different degrees of deviation
    • Rossi MA and Cecchini G. Lipid peroxidation in hepatomas of different degrees of deviation. Cell Biochem Funct 1: 49-54, 1983.
    • (1983) Cell Biochem Funct , vol.1 , pp. 49-54
    • Rossi, M.A.1    Cecchini, G.2
  • 169
    • 0021238760 scopus 로고
    • Alzheimer's disease brain: Alterations in RNA levels and in a ribonuclease- inhibitor complex
    • Sajdel-Sulkowska EM and Marotta CA. Alzheimer's disease brain: alterations in RNA levels and in a ribonuclease- inhibitor complex. Science 225: 947-949, 1984.
    • (1984) Science , vol.225 , pp. 947-949
    • Sajdel-Sulkowska, E.M.1    Marotta, C.A.2
  • 170
    • 81755182703 scopus 로고    scopus 로고
    • Critical insights into cardiovascular disease from basic research on the oxidation of phospholipids: The c-hydroxyalkenal phospholipid hypothesis
    • Salomon RG and Gu X. Critical insights into cardiovascular disease from basic research on the oxidation of phospholipids: the c-hydroxyalkenal phospholipid hypothesis. Chem Res Toxicol 24: 1791-1802, 2011.
    • (2011) Chem Res Toxicol , vol.24 , pp. 1791-1802
    • Salomon, R.G.1    Gu, X.2
  • 171
    • 0033929845 scopus 로고    scopus 로고
    • HNE-derived 2-pentylpyrroles are generated during oxidation of LDL, are more prevalent in blood plasma from patients with renal disease or atherosclerosis, and are present in atherosclerotic plaques
    • Salomon RG, Kaur K, Podrez E, Hoff HF, Krushinsky AV, and Sayre LM. HNE-derived 2-pentylpyrroles are generated during oxidation of LDL, are more prevalent in blood plasma from patients with renal disease or atherosclerosis, and are present in atherosclerotic plaques. Chem Res Toxicol: 557-564, 2000.
    • (2000) Chem Res Toxicol , pp. 557-564
    • Salomon, R.G.1    Kaur, K.2    Podrez, E.3    Hoff, H.F.4    Krushinsky, A.V.5    Sayre, L.M.6
  • 172
    • 0035856949 scopus 로고    scopus 로고
    • Insulin signalling and the regulation of glucose and lipid metabolism
    • Saltiel AR and Kahn CR. Insulin signalling and the regulation of glucose and lipid metabolism. Nature 414: 799-806, 2001.
    • (2001) Nature , vol.414 , pp. 799-806
    • Saltiel, A.R.1    Kahn, C.R.2
  • 173
    • 84884902071 scopus 로고    scopus 로고
    • Oxidative damage to macromolecules in human Parkinson disease and the rotenone model
    • Sanders LH and Greenamyre JT. Oxidative damage to macromolecules in human Parkinson disease and the rotenone model. Free Radic Biol Med 62: 111-120, 2013.
    • (2013) Free Radic Biol Med , vol.62 , pp. 111-120
    • Sanders, L.H.1    Greenamyre, J.T.2
  • 174
    • 0036884424 scopus 로고    scopus 로고
    • A blast from the past: Clearance of apoptotic cells regulates immune responses
    • Savill J, Dransfield I., Gregory C, and Haslett C. A blast from the past: clearance of apoptotic cells regulates immune responses. Nat Rev Immunol 2: 965-975, 2002.
    • (2002) Nat Rev Immunol , vol.2 , pp. 965-975
    • Savill, J.1    Dransfield, I.2    Gregory, C.3    Haslett, C.4
  • 176
    • 0028869597 scopus 로고
    • Human diseases with defects in oxidative phosphorylation. 2. F1F0 ATP-synthase defects in Alzheimer disease revealed by blue native polyacrylamide gel electrophoresis
    • Schägger H and Ohm TG. Human diseases with defects in oxidative phosphorylation. 2. F1F0 ATP-synthase defects in Alzheimer disease revealed by blue native polyacrylamide gel electrophoresis. Eur J Biochem 227: 916-921, 1995.
    • (1995) Eur J Biochem , vol.227 , pp. 916-921
    • Schägger, H.1    Ohm, T.G.2
  • 177
    • 79957872121 scopus 로고    scopus 로고
    • Synaptic loss in the inferior temporal gyrus in mild cognitive impairment and Alzheimer's disease
    • Scheff SW, Price DA, Schmitt FA, Scheff MA, and Mufson EJ. Synaptic loss in the inferior temporal gyrus in mild cognitive impairment and Alzheimer's disease. J Alzheimers Dis 24: 547-557, 2011.
    • (2011) J Alzheimers Dis , vol.24 , pp. 547-557
    • Scheff, S.W.1    Price, D.A.2    Schmitt, F.A.3    Scheff, M.A.4    Mufson, E.J.5
  • 179
    • 0030993254 scopus 로고    scopus 로고
    • Immunologically restricted and inhibitory anti-Ro/SSA in monozygotic twins
    • Scofield RH, Kurien BT, and Reichlin M. Immunologically restricted and inhibitory anti-Ro/SSA in monozygotic twins. Lupus 6: 395-398, 1997.
    • (1997) Lupus , vol.6 , pp. 395-398
    • Scofield, R.H.1    Kurien, B.T.2    Reichlin, M.3
  • 180
    • 0035991444 scopus 로고    scopus 로고
    • In situ detection of lipid peroxidation and oxidative DNA damage in non-alcoholic fatty liver disease
    • Seki S, Kitada T, Yamada T, Sakaguchi H, Nakatani K, and Wakasa K. In situ detection of lipid peroxidation and oxidative DNA damage in non-alcoholic fatty liver disease. J Hepatol 37: 56-62, 2002.
    • (2002) J Hepatol , vol.37 , pp. 56-62
    • Seki, S.1    Kitada, T.2    Yamada, T.3    Sakaguchi, H.4    Nakatani, K.5    Wakasa, K.6
  • 181
    • 0025890160 scopus 로고
    • Oxidation and reduction of 4-hydroxyalkenals catalyzed by isozymes of human alcohol dehydrogenase
    • Sellin S, Holmquist B, Mannervik B, and Vallee BL. Oxidation and reduction of 4-hydroxyalkenals catalyzed by isozymes of human alcohol dehydrogenase. Biochemistry 30: 2514-2518, 1991.
    • (1991) Biochemistry , vol.30 , pp. 2514-2518
    • Sellin, S.1    Holmquist, B.2    Mannervik, B.3    Vallee, B.L.4
  • 182
    • 36749104186 scopus 로고    scopus 로고
    • In parkinsonian substantia nigra, alpha-synuclein is modified by acrolein, a lipid-peroxidation product, and accumulates in the dopamine neurons with inhibition of proteasome activity
    • Shamoto-Nagai M, Maruyama W, Hashizume Y, Yoshida M, Osawa T, Riederer P, and Naoi M. In parkinsonian substantia nigra, alpha-synuclein is modified by acrolein, a lipid-peroxidation product, and accumulates in the dopamine neurons with inhibition of proteasome activity. J Neural Transm 114: 1559-1567, 2007.
    • (2007) J Neural Transm , vol.114 , pp. 1559-1567
    • Shamoto-Nagai, M.1    Maruyama, W.2    Hashizume, Y.3    Yoshida, M.4    Osawa, T.5    Riederer, P.6    Naoi, M.7
  • 183
    • 79956146841 scopus 로고    scopus 로고
    • A-Tocopherol suppresses lipid peroxidation and behavioral and cognitive impairments in the Ts65Dn mouse model of Down syndrome
    • Shichiri M, Yoshida Y, Ishida N, Hagihara Y, Iwahashi H, Tamai H, and Niki E. a-Tocopherol suppresses lipid peroxidation and behavioral and cognitive impairments in the Ts65Dn mouse model of Down syndrome. Free Radic Biol Med 50: 1801-1811, 2011.
    • (2011) Free Radic Biol Med , vol.50 , pp. 1801-1811
    • Shichiri, M.1    Yoshida, Y.2    Ishida, N.3    Hagihara, Y.4    Iwahashi, H.5    Tamai, H.6    Niki, E.7
  • 185
    • 33846949357 scopus 로고    scopus 로고
    • The oxidative stress metabolite 4-hydroxynonenal promotes Alzheimer protofibril formation
    • Siegel SJ, Bieschke J, Powers ET, and Kelly JW. The oxidative stress metabolite 4-hydroxynonenal promotes Alzheimer protofibril formation. Biochemistry 46: 1503-1510, 2007.
    • (2007) Biochemistry , vol.46 , pp. 1503-1510
    • Siegel, S.J.1    Bieschke, J.2    Powers, E.T.3    Kelly, J.W.4
  • 186
    • 3242690619 scopus 로고    scopus 로고
    • Asymmetric dimethylarginine upregulates LOX-1 in activated macrophages: Role in foam cell formation
    • Smirnova IV, Kajstura M, Sawamura T, and Goligorsky MS. Asymmetric dimethylarginine upregulates LOX-1 in activated macrophages: role in foam cell formation. Am J Physiol Heart Circ Physiol 287: 782-790, 2004.
    • (2004) Am J Physiol Heart Circ Physiol , vol.287 , pp. 782-790
    • Smirnova, I.V.1    Kajstura, M.2    Sawamura, T.3    Goligorsky, M.S.4
  • 188
    • 0028937501 scopus 로고
    • Role of oxidized LDL and antioxidants in atherosclerosis
    • Steinberg D. Role of oxidized LDL and antioxidants in atherosclerosis. Adv Exp Med Biol 369: 39-48, 1995.
    • (1995) Adv Exp Med Biol , vol.369 , pp. 39-48
    • Steinberg, D.1
  • 189
    • 0024603895 scopus 로고
    • Beyond cholesterol: Modifications of lowdensity lipoprotein that increase its atherogenicity
    • Steinberg D, Parthasarathy S, Carew TE, Khoo JC, and Wittztum JL. Beyond cholesterol: modifications of lowdensity lipoprotein that increase its atherogenicity. N Engl J Med 320: 915-924, 1989.
    • (1989) N Engl J Med , vol.320 , pp. 915-924
    • Steinberg, D.1    Parthasarathy, S.2    Carew, T.E.3    Khoo, J.C.4    Wittztum, J.L.5
  • 190
    • 0033521695 scopus 로고    scopus 로고
    • Receptors for oxidized low density lipoprotein
    • Steinbrecher UP. Receptors for oxidized low density lipoprotein. Biochim Biophys Acta 1436: 279-298, 1999.
    • (1999) Biochim Biophys Acta , vol.1436 , pp. 279-298
    • Steinbrecher, U.P.1
  • 192
    • 84884877254 scopus 로고    scopus 로고
    • Lipid peroxidation triggers neurodegeneration: A redox proteomics view into the Alzheimer disease brain
    • Sultana R, Perluigi M, and Butterfield AD. Lipid peroxidation triggers neurodegeneration: a redox proteomics view into the Alzheimer disease brain. Free Radic Biol Med 62: 157-169, 2013.
    • (2013) Free Radic Biol Med , vol.62 , pp. 157-169
    • Sultana, R.1    Perluigi, M.2    Butterfield, A.D.3
  • 194
    • 0037204685 scopus 로고    scopus 로고
    • Novel bioactive phospholipids: Practical total syntheses of products from the oxidation of arachidonic and linoleic esters of 2-lysophosphatidylcholine
    • Sun M, Deng Y, Batyreva E, Sha W, and Salomon RG. Novel bioactive phospholipids: practical total syntheses of products from the oxidation of arachidonic and linoleic esters of 2-lysophosphatidylcholine. J Biol Chem 67: 3575-3584, 2002.
    • (2002) J Biol Chem , vol.67 , pp. 3575-3584
    • Sun, M.1    Deng, Y.2    Batyreva, E.3    Sha, W.4    Salomon, R.G.5
  • 195
    • 84896722464 scopus 로고    scopus 로고
    • Adaptive immune responses triggered by oxidative stress contribute to hepatic inflammation in NASH
    • Sutti S, Jindal A, Vacchiano M, Gigliotti L, Bozzola C, and Albano E. Adaptive immune responses triggered by oxidative stress contribute to hepatic inflammation in NASH. Hepatology 59: 886-897, 2014.
    • (2014) Hepatology , vol.59 , pp. 886-897
    • Sutti, S.1    Jindal, A.2    Vacchiano, M.3    Gigliotti, L.4    Bozzola, C.5    Albano, E.6
  • 197
    • 34447542267 scopus 로고    scopus 로고
    • Modification by acrolein, a component of tobacco smoke and age-related oxidative stress, mediates functional impairment of human apolipoprotein e
    • Tamamizu-Kato S, Wong JY, Jairam V, and Uchida K. Modification by acrolein, a component of tobacco smoke and age-related oxidative stress, mediates functional impairment of human apolipoprotein E. Biochemistry 46: 8392-8400, 2007.
    • (2007) Biochemistry , vol.46 , pp. 8392-8400
    • Tamamizu-Kato, S.1    Wong, J.Y.2    Jairam, V.3    Uchida, K.4
  • 198
    • 0032874302 scopus 로고    scopus 로고
    • Formation and export of the glutathione conjugate of 4-hydroxy-2, 3-Enonenal (4-HNE) in hepatoma cells
    • Tjalkens RB, Cook LW, and Petersen DR. Formation and export of the glutathione conjugate of 4-hydroxy-2, 3-Enonenal (4-HNE) in hepatoma cells. Arch Biochem Biophys 361: 113-119, 1999.
    • (1999) Arch Biochem Biophys , vol.361 , pp. 113-119
    • Tjalkens, R.B.1    Cook, L.W.2    Petersen, D.R.3
  • 200
    • 67650071137 scopus 로고    scopus 로고
    • Targeting cancer cells by ROS-mediated mechanisms: A radical therapeutic approach?
    • Trachootham D, Alexandre J, and Huang P. Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach? Nat Rev Drug Discov 8: 579-591, 2009.
    • (2009) Nat Rev Drug Discov , vol.8 , pp. 579-591
    • Trachootham, D.1    Alexandre, J.2    Huang, P.3
  • 202
    • 0037411282 scopus 로고    scopus 로고
    • 4-Hydroxy-2-nonenal: A product and mediator of oxidative stress
    • Uchida K. 4-Hydroxy-2-nonenal: a product and mediator of oxidative stress. Prog Lipid Res 42: 318-343, 2003.
    • (2003) Prog Lipid Res , vol.42 , pp. 318-343
    • Uchida, K.1
  • 205
    • 0031260402 scopus 로고    scopus 로고
    • Protein modification by lipid peroxidation products: Formation of malondialdehyde-derived Ne-(2-propenal)lysine in proteins
    • Uchida K, Sakai K, Itakura K, Osawa T, and Toyokuni S. Protein modification by lipid peroxidation products: formation of malondialdehyde-derived Ne-(2-propenal)lysine in proteins. Arch Biochem Biophys 346: 45-52, 1997.
    • (1997) Arch Biochem Biophys , vol.346 , pp. 45-52
    • Uchida, K.1    Sakai, K.2    Itakura, K.3    Osawa, T.4    Toyokuni, S.5
  • 206
    • 82955237301 scopus 로고    scopus 로고
    • Hydroxyalkenals and oxidized phospholipids modulation of endothelial cytoskeleton, focal adhesion and adherens junction proteins in regulating endothelial barrier function
    • Usatyuk PV and Natarajan V. Hydroxyalkenals and oxidized phospholipids modulation of endothelial cytoskeleton, focal adhesion and adherens junction proteins in regulating endothelial barrier function. Microvasc Res 83: 45-55, 2012.
    • (2012) Microvasc Res , vol.83 , pp. 45-55
    • Usatyuk, P.V.1    Natarajan, V.2
  • 207
    • 79151484549 scopus 로고    scopus 로고
    • Oxidized LDL enhances proinflammatory responses of alternatively activated M2 macrophages: A crucial role for Kruppel-like factor 2
    • van Tits LJ, Stienstra R, van Lent PL, Netea MG, Joosten LA, and Stalenhoef AF. Oxidized LDL enhances proinflammatory responses of alternatively activated M2 macrophages: a crucial role for Kruppel-like factor 2. Atherosclerosis 214: 345-349, 2011.
    • (2011) Atherosclerosis , vol.214 , pp. 345-349
    • Van Tits, L.J.1    Stienstra, R.2    Van Lent, P.L.3    Netea, M.G.4    Joosten, L.A.5    Stalenhoef, A.F.6
  • 208
    • 0032962921 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptors (PPARS) and carcinogenesis
    • Vanden Heuvel JP. Peroxisome proliferator-activated receptors (PPARS) and carcinogenesis. Toxicol Sci 47: 1-8, 1999.
    • (1999) Toxicol Sci , vol.47 , pp. 1-8
    • Vanden Heuvel, J.P.1
  • 210
    • 33646372991 scopus 로고    scopus 로고
    • Reactive lipid species from cyclooxygenase-2 inactivate tumor suppressor LKB1/STK11: Cyclopentenone prostaglandins and 4- hydroxy-2-nonenal covalently modify and inhibit the ampkinase kinase thatmodulates cellular energy homeostasis and protein translation
    • Wagner TM, Mullally JE, and Fitzpatrick FA. Reactive lipid species from cyclooxygenase-2 inactivate tumor suppressor LKB1/STK11: cyclopentenone prostaglandins and 4- hydroxy-2-nonenal covalently modify and inhibit the ampkinase kinase thatmodulates cellular energy homeostasis and protein translation. J Biol Chem 281: 2598-2604, 2006.
    • (2006) J Biol Chem , vol.281 , pp. 2598-2604
    • Wagner, T.M.1    Mullally, J.E.2    Fitzpatrick, F.A.3
  • 211
    • 77953503390 scopus 로고    scopus 로고
    • Markers of oxidative and nitrosative stress in systemic lupus erythematosus: Correlation with disease activity
    • Wang G, Pierangeli SS, Papalardo E, Ansari GAS, and Khan F. Markers of oxidative and nitrosative stress in systemic lupus erythematosus: correlation with disease activity. Arthritis Rheum 62: 2064-2072, 2010.
    • (2010) Arthritis Rheum , vol.62 , pp. 2064-2072
    • Wang, G.1    Pierangeli, S.S.2    Papalardo, E.3    Ansari, G.A.S.4    Khan, F.5
  • 212
    • 84862617186 scopus 로고    scopus 로고
    • 4-hydroxynonenal differentially regulates adiponectin gene expression and secretion via activating PPAR and accelerating ubiquitin-proteasome degradation
    • Wang Z, Dou X, Gu D, Shen C, Yao T, Nguyen V, Braunschweig C, and Song Z. 4-hydroxynonenal differentially regulates adiponectin gene expression and secretion via activating PPAR and accelerating ubiquitin-proteasome degradation. Mol Cell Endocrinol 349: 222-231, 2012.
    • (2012) Mol Cell Endocrinol , vol.349 , pp. 222-231
    • Wang, Z.1    Dou, X.2    Gu, D.3    Shen, C.4    Yao, T.5    Nguyen, V.6    Braunschweig, C.7    Song, Z.8
  • 213
  • 214
    • 84863986254 scopus 로고    scopus 로고
    • The innate immune response to products of phospholipid peroxidation
    • Weismann D and Binder CJ. The innate immune response to products of phospholipid peroxidation. Biochim Biophys Acta 1818: 2465-2475, 2012.
    • (2012) Biochim Biophys Acta , vol.1818 , pp. 2465-2475
    • Weismann, D.1    Binder, C.J.2
  • 215
    • 0036710280 scopus 로고    scopus 로고
    • IRS proteins and the common path to diabetes
    • White MF. IRS proteins and the common path to diabetes. Am J Physiol Endocrinol Metab 283: 413-422, 2002.
    • (2002) Am J Physiol Endocrinol Metab , vol.283 , pp. 413-422
    • White, M.F.1
  • 216
    • 0037030657 scopus 로고    scopus 로고
    • Structure-activity relationship studies of nordihydroguaiaretic acid inhibitors toward soybean, 12-human, and 15-human lipoxygenase
    • Whitman S, GezginciM, Timmermann BN, and Holman TR. Structure-activity relationship studies of nordihydroguaiaretic acid inhibitors toward soybean, 12-human, and 15-human lipoxygenase. J Med Chem 45: 2659-2661, 2002.
    • (2002) J Med Chem , vol.45 , pp. 2659-2661
    • Whitman, S.1    Gezgincim Timmermann, B.N.2    Holman, T.R.3
  • 217
    • 0023009007 scopus 로고
    • Formation of cyclic adducts of deoxyguanosine with the aldehydes trans-4-hydroxy-2-hexenal and trans-4-hydroxy-2-nonenal in vitro
    • Winter CK, Segall HJ, and Haddon WF. Formation of cyclic adducts of deoxyguanosine with the aldehydes trans-4-hydroxy-2-hexenal and trans-4-hydroxy-2-nonenal in vitro. Cancer Res 46: 5682-5686, 1986.
    • (1986) Cancer Res , vol.46 , pp. 5682-5686
    • Winter, C.K.1    Segall, H.J.2    Haddon, W.F.3
  • 218
    • 0032854884 scopus 로고    scopus 로고
    • T-cell recognition of lipid peroxidation products breaks tolerance to self proteins
    • Wuttge DM, Bruzelius M, and Stemme S. T-cell recognition of lipid peroxidation products breaks tolerance to self proteins. Immunology 98: 273-279, 1999.
    • (1999) Immunology , vol.98 , pp. 273-279
    • Wuttge, D.M.1    Bruzelius, M.2    Stemme, S.3
  • 219
    • 77956924939 scopus 로고    scopus 로고
    • Lectin-like oxidized low-density lipoprotein receptor-1 delivers heat shock protein-60 fused antigen into the MHC class i presentation pathway
    • Xie J, Zhu H, Guo L, Ruan Y, Wang L, Sun L, Zhou L, Wu W, Yun X, Shen A, and Gu J. Lectin-like oxidized low-density lipoprotein receptor-1 delivers heat shock protein-60 fused antigen into the MHC class I presentation pathway. J Immunol 185: 2306-2313, 2010.
    • (2010) J Immunol , vol.185 , pp. 2306-2313
    • Xie, J.1    Zhu, H.2    Guo, L.3    Ruan, Y.4    Wang, L.5    Sun, L.6    Zhou, L.7    Wu, W.8    Yun, X.9    Shen, A.10    Gu, J.11
  • 220
    • 0032871586 scopus 로고    scopus 로고
    • Rapid crosslinking of proteins by 4-ketoaldehydes and 4-hydroxy- 2-alkenals does not arise from the lysine-derived monoalkylpyrroles
    • Xu G, Liu Y, Kansal MM, and Sayre LM. Rapid crosslinking of proteins by 4-ketoaldehydes and 4-hydroxy- 2-alkenals does not arise from the lysine-derived monoalkylpyrroles. Chem Res Toxicol 12: 855-861, 1999.
    • (1999) Chem Res Toxicol , vol.12 , pp. 855-861
    • Xu, G.1    Liu, Y.2    Kansal, M.M.3    Sayre, L.M.4
  • 221
    • 0025180671 scopus 로고
    • Immunology of atherosclerosis cellular composition and major histocompatibility complex class II antigen expression in aortic intima, fatty streaks, and atherosclerotic plaques in young and aged human specimens
    • Xu QB, Oberhuber G, Gruschwitz M, and Wick G. Immunology of atherosclerosis cellular composition and major histocompatibility complex class II antigen expression in aortic intima, fatty streaks, and atherosclerotic plaques in young and aged human specimens. Clin Immunol Immunopathol 56: 344-359, 1990.
    • (1990) Clin Immunol Immunopathol , vol.56 , pp. 344-359
    • Xu, Q.B.1    Oberhuber, G.2    Gruschwitz, M.3    Wick, G.4
  • 223
    • 84908143823 scopus 로고    scopus 로고
    • Activation of peroxisome proliferator-activated receptor-b/d (PPAR-b/d) inhibits human breast cancer cell line tumorigenicity
    • Yao PL, Morales JL, Zhu B, Kang BH, Gonzalez FJ, and Peters JM. Activation of peroxisome proliferator-activated receptor-b/d (PPAR-b/d) inhibits human breast cancer cell line tumorigenicity. Mol Cancer Ther 13: 1008- 1017, 2014.
    • (2014) Mol Cancer Ther , vol.13 , pp. 1008-1017
    • Yao, P.L.1    Morales, J.L.2    Zhu, B.3    Kang, B.H.4    Gonzalez, F.J.5    Peters, J.M.6
  • 225
    • 0032528913 scopus 로고    scopus 로고
    • Identification of the lectin-like receptor for oxidized low-density lipoprotein in human macrophages and its potential role as a scavenger receptor
    • Yoshida H, Kondratenko N, Green S, Steinberg D, and Quehenberger O. Identification of the lectin-like receptor for oxidized low-density lipoprotein in human macrophages and its potential role as a scavenger receptor. Biochem J 334: 9-13, 1998.
    • (1998) Biochem J , vol.334 , pp. 9-13
    • Yoshida, H.1    Kondratenko, N.2    Green, S.3    Steinberg, D.4    Quehenberger, O.5
  • 228
    • 0033511794 scopus 로고    scopus 로고
    • Correlation of increased susceptibility to apoptosis of CD4+ T cells with lymphocyte activation and activity of disease in patients with primary Sjögren's syndrome
    • Zeher M, Szodoray P, Gyimesi E, and Szondy Z. Correlation of increased susceptibility to apoptosis of CD4+ T cells with lymphocyte activation and activity of disease in patients with primary Sjögren's syndrome. Arthritis Rheum 42: 1673-1681, 1999.
    • (1999) Arthritis Rheum , vol.42 , pp. 1673-1681
    • Zeher, M.1    Szodoray, P.2    Gyimesi, E.3    Szondy, Z.4
  • 229


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.