Potential toxicity of flavonoids and other dietary phenolics: Significance for their chemopreventive and anticancer properties

Free Radical Biology and Medicine

Volumn 37, Issue 3, 2004, Pages 287-303

  Galati, Giuseppe ^a   O'Brien, Peter J ^a,b  

^a UNIVERSITY OF TORONTO   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

Author keywords

m; AhR; alanine aminotransferase; ALT; Anticancer; aryl hydrocarbon receptor; CDK; Chemoprevention; cyclin dependent kinase; CYP; cytochrome P450; DMBA; Flavonoids; Free radicals; Isoflavones; mitochondrial membrane potential; Toxicity

Indexed keywords

ANTINEOPLASTIC AGENT; ANTIOXIDANT; APIGENIN; BAICALIN; CALCIUM CHANNEL BLOCKING AGENT; CAPSAICIN; CATECHIN; CHRYSIN; COUMARIC ACID; CURCUMIN; DIOSMETIN; DIOSMIN; ELLAGIC ACID; EPIGALLOCATECHIN GALLATE; ETOPOSIDE; FISETIN; FLAVONOID; FLAVOPIRIDOL; GALANGIN; KAEMPFEROL; MYRICETIN; NARINGENIN; NORDIHYDROGUAIARETIC ACID; PHENOL DERIVATIVE; QUERCETIN; RESVERATROL; ROTENONE; TANGERETIN; TANNIN; UNINDEXED DRUG;

ANTINEOPLASTIC ACTIVITY; ANTIOXIDANT ACTIVITY; APOPTOSIS; BLOOD TOXICITY; BREAST CANCER; CANCER INHIBITION; CANCER THERAPY; CARCINOGENESIS; CHEMOPROPHYLAXIS; CHRONIC HEPATITIS; CLINICAL TRIAL; CONTACT DERMATITIS; DERMATITIS; DIARRHEA; DIET; DNA SYNTHESIS; DOWN REGULATION; DRUG ACTIVITY; DRUG SAFETY; ENZYME INHIBITION; FEMALE FERTILITY; HEMOLYTIC ANEMIA; HUMAN; LIVER FAILURE; LIVER TOXICITY; METABOLIC ACTIVATION; MITOCHONDRIAL TOXICITY; MYELOID LEUKEMIA; NEPHROTOXICITY; NONHUMAN; PAPILLOMA; PRIORITY JOURNAL; PROSTATE CANCER; REPRODUCTIVE HEALTH; REVIEW; SEXUAL DYSFUNCTION; SIGNAL TRANSDUCTION; TEA; TUMOR GROWTH;

ANIMALS; DIETARY SUPPLEMENTS; DRUG INTERACTIONS; DRUG TOXICITY; FLAVONOIDS; HUMANS; NEOPLASMS; PHENOLS;

ANIMALIA;

EID: 3042574709     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2004.04.034     Document Type: Review

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