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The only available comprehensive review of 3D structures of TIR domains from animals, plants and bacteria.
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Identification of interaction sites for dimerization and adapter recruitment in Toll/interleukin-1 receptor (TIR) domain of Toll-like receptor 4
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The mammalian two-hybrid system MAPPIT and extensive mutagenesis were combined with the available crystallographic and NMR data and computational modelling to suggest the structure of the MyD88 TIR-domain signalosome.
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