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Volumn 287, Issue 37, 2012, Pages 30993-31002

Toll/interleukin-1 receptor domain dimers as the platform for activation and enhanced inhibition of toll-like receptor signaling

Author keywords

[No Author keywords available]

Indexed keywords

COILED COIL; DIMERIZATION DOMAIN; DOMAIN-CONTAINING PROTEINS; LIMITING STEP; RECEPTOR ACTIVATION; RECEPTOR DOMAINS; SIGNALING PATHWAYS; TOLL-LIKE RECEPTORS; WIDE SPECTRUM;

EID: 84866072549     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.376186     Document Type: Article
Times cited : (27)

References (41)
  • 1
    • 3142724031 scopus 로고    scopus 로고
    • Toll-like receptor signaling
    • Akira, S., and Takeda, K. (2004) Toll-like receptor signaling. Nat. Rev. Immunol. 4, 499-511
    • (2004) Nat. Rev. Immunol. , vol.4 , pp. 499-511
    • Akira, S.1    Takeda, K.2
  • 2
    • 34247566510 scopus 로고    scopus 로고
    • The family of five: TIR domain-containing adaptors in Toll-like receptor signaling
    • O'Neill, L. A., and Bowie, A. G. (2007) The family of five: TIR domain-containing adaptors in Toll-like receptor signaling. Nat. Reviews Immunol. 7, 353-364
    • (2007) Nat. Reviews Immunol. , vol.7 , pp. 353-364
    • O'Neill, L.A.1    Bowie, A.G.2
  • 3
    • 34548459868 scopus 로고    scopus 로고
    • Structure and function of Toll receptors and their ligands
    • Gay, N. J., and Gangloff, M. (2007) Structure and function of Toll receptors and their ligands. Annu. Rev. Biochem. 76, 141-165
    • (2007) Annu. Rev. Biochem. , vol.76 , pp. 141-165
    • Gay, N.J.1    Gangloff, M.2
  • 4
    • 45549086115 scopus 로고    scopus 로고
    • The crystal structure of the human toll-like receptor 10 cytoplasmic domain reveals a putative signaling dimer
    • Nyman, T., Stenmark, P., Flodin, S., Johansson, I., Hammarström, M., and Nordlund, P. (2008) The crystal structure of the human toll-like receptor 10 cytoplasmic domain reveals a putative signaling dimer. J. Biol. Chem. 283, 11861-11865
    • (2008) J. Biol. Chem. , vol.283 , pp. 11861-11865
    • Nyman, T.1    Stenmark, P.2    Flodin, S.3    Johansson, I.4    Hammarström, M.5    Nordlund, P.6
  • 5
    • 40749097627 scopus 로고    scopus 로고
    • A dimer of the Toll-like receptor 4 cytoplasmic domain provides a specific scaffold for the recruitment of signaling adaptor proteins
    • Nuñez Miguel, R., Wong, J., Westoll, J. F., Brooks, H. J., O'Neill, L. A., Gay, N. J., Bryant, C. E., and Monie, T. P. (2007) A dimer of the Toll-like receptor 4 cytoplasmic domain provides a specific scaffold for the recruitment of signaling adaptor proteins. PLoS One 2, e788
    • (2007) PLoS One , vol.2
    • Nuñez Miguel, R.1    Wong, J.2    Westoll, J.F.3    Brooks, H.J.4    O'Neill, L.A.5    Gay, N.J.6    Bryant, C.E.7    Monie, T.P.8
  • 6
    • 0031015564 scopus 로고    scopus 로고
    • The cloning and characterization of human MyD88: A member of an IL-1 receptor related family
    • Bonnert, T. P., Garka, K. E., Parnet, P., Sonoda, G., Testa, J. R., and Sims, J. E. (1997) The cloning and characterization of human MyD88: a member of an IL-1 receptor related family. FEBS Lett. 402, 81-84
    • (1997) FEBS Lett. , vol.402 , pp. 81-84
    • Bonnert, T.P.1    Garka, K.E.2    Parnet, P.3    Sonoda, G.4    Testa, J.R.5    Sims, J.E.6
  • 9
    • 0037454946 scopus 로고    scopus 로고
    • Inhibition of interleukin 1 receptor/Toll-like receptor signaling through the alternatively spliced, short form of MyD88 is due to its failure to recruit IRAK-4
    • Burns, K., Janssens, S., Brissoni, B., Olivos, N., Beyaert, R., and Tschopp, J. (2003) Inhibition of interleukin 1 receptor/Toll-like receptor signaling through the alternatively spliced, short form of MyD88 is due to its failure to recruit IRAK-4. J. Exp. Med. 197, 263-268
    • (2003) J. Exp. Med. , vol.197 , pp. 263-268
    • Burns, K.1    Janssens, S.2    Brissoni, B.3    Olivos, N.4    Beyaert, R.5    Tschopp, J.6
  • 10
    • 77953714711 scopus 로고    scopus 로고
    • Helical assembly in the MyD88- IRAK4-IRAK2 complex in TLR/IL-1R signaling
    • Lin, S. C., Lo, Y. C., and Wu, H. (2010) Helical assembly in the MyD88- IRAK4-IRAK2 complex in TLR/IL-1R signaling. Nature 465, 885-890
    • (2010) Nature , vol.465 , pp. 885-890
    • Lin, S.C.1    Lo, Y.C.2    Wu, H.3
  • 11
    • 34250842580 scopus 로고    scopus 로고
    • Distinct roles of TIR and non-TIR regions in the subcellular localization and signaling properties of MyD88
    • Nishiya, T., Kajita, E., Horinouchi, T., Nishimoto, A., and Miwa, S. (2007) Distinct roles of TIR and non-TIR regions in the subcellular localization and signaling properties of MyD88. FEBS Lett. 581, 3223-3229
    • (2007) FEBS Lett. , vol.581 , pp. 3223-3229
    • Nishiya, T.1    Kajita, E.2    Horinouchi, T.3    Nishimoto, A.4    Miwa, S.5
  • 15
    • 65649148280 scopus 로고    scopus 로고
    • Brucella TIR domain-containing protein mimics properties of the Toll-like receptor adaptor protein TIRAP
    • Radhakrishnan, G. K., Yu, Q., Harms, J. S., and Splitter, G. A. (2009) Brucella TIR domain-containing protein mimics properties of the Toll-like receptor adaptor protein TIRAP. J. Biol. Chem. 284, 9892-9898
    • (2009) J. Biol. Chem. , vol.284 , pp. 9892-9898
    • Radhakrishnan, G.K.1    Yu, Q.2    Harms, J.S.3    Splitter, G.A.4
  • 18
    • 0028306360 scopus 로고
    • Subdomain folding of the coiled coil leucine zipper from the bZIP transcriptional activator GCN4
    • Lumb, K. J., Carr, C. M., and Kim, P. S. (1994) Subdomain folding of the coiled coil leucine zipper from the bZIP transcriptional activator GCN4. Biochemistry 33, 7361-7367
    • (1994) Biochemistry , vol.33 , pp. 7361-7367
    • Lumb, K.J.1    Carr, C.M.2    Kim, P.S.3
  • 19
    • 33747840389 scopus 로고    scopus 로고
    • GRAMM-X public web server for protein-protein docking
    • Tovchigrechko, A., and Vakser, I. A. (2006) GRAMM-X public web server for protein-protein docking. Nucleic Acids Res. 34, W310-314
    • (2006) Nucleic Acids Res. , vol.34
    • Tovchigrechko, A.1    Vakser, I.A.2
  • 20
    • 0026356891 scopus 로고
    • Predicting coiled coils from protein sequences
    • Lupas, A., Van Dyke, M., and Stock, J. (1991) Predicting coiled coils from protein sequences. Science 252, 1162-1164
    • (1991) Science , vol.252 , pp. 1162-1164
    • Lupas, A.1    Van Dyke, M.2    Stock, J.3
  • 21
    • 80052688676 scopus 로고    scopus 로고
    • The role of intermediary domain of MyD88 in cell activation and therapeutic inhibition of TLRs
    • Avbelj, M., Horvat, S., and Jerala, R. (2011) The role of intermediary domain of MyD88 in cell activation and therapeutic inhibition of TLRs. J. Immunol. 187, 2394-2404
    • (2011) J. Immunol. , vol.187 , pp. 2394-2404
    • Avbelj, M.1    Horvat, S.2    Jerala, R.3
  • 23
    • 54549105754 scopus 로고    scopus 로고
    • AccPbFRET: An ImageJ plugin for semi-automatic, fully corrected analysis of acceptor photobleaching FRET images
    • Roszik, J., Szöllosi, J., and Vereb, G. (2008) AccPbFRET: an ImageJ plugin for semi-automatic, fully corrected analysis of acceptor photobleaching FRET images. BMC Bioinformatics 9, 346
    • (2008) BMC Bioinformatics , vol.9 , pp. 346
    • Roszik, J.1    Szöllosi, J.2    Vereb, G.3
  • 24
    • 79953180063 scopus 로고    scopus 로고
    • Natural loss-of-function mutation of myeloid differentiation protein 88 disrupts its ability to form Myddosomes
    • Nagpal, K., Plantinga, T. S., Sirois, C. M., Monks, B. G., Latz, E., Netea, M. G., and Golenbock, D. T. (2011) Natural loss-of-function mutation of myeloid differentiation protein 88 disrupts its ability to form Myddosomes. J. Biol. Chem. 286, 11875-11882
    • (2011) J. Biol. Chem. , vol.286 , pp. 11875-11882
    • Nagpal, K.1    Plantinga, T.S.2    Sirois, C.M.3    Monks, B.G.4    Latz, E.5    Netea, M.G.6    Golenbock, D.T.7
  • 25
    • 0037021421 scopus 로고    scopus 로고
    • Integrin-nucleated Toll-like receptor (TLR) dimerization reveals subcellular targeting of TLRs and distinct mechanisms of TLR4 activation and signaling
    • Zhang, H., Tay, P. N., Cao, W., Li, W., and Lu, J. (2002) Integrin-nucleated Toll-like receptor (TLR) dimerization reveals subcellular targeting of TLRs and distinct mechanisms of TLR4 activation and signaling. FEBS Lett. 532, 171-176
    • (2002) FEBS Lett. , vol.532 , pp. 171-176
    • Zhang, H.1    Tay, P.N.2    Cao, W.3    Li, W.4    Lu, J.5
  • 26
    • 79959536183 scopus 로고    scopus 로고
    • The ectodomain of the Toll-like receptor 4 prevents constitutive receptor activation
    • Panter, G., and Jerala, R. (2011) The ectodomain of the Toll-like receptor 4 prevents constitutive receptor activation. J. Biol. Chem. 286, 23334-23344
    • (2011) J. Biol. Chem. , vol.286 , pp. 23334-23344
    • Panter, G.1    Jerala, R.2
  • 27
    • 29644438009 scopus 로고    scopus 로고
    • Identification and characterization of a novel bacterial virulence factor that shares homology with mammalian Toll/interleukin-1 receptor family proteins
    • Newman, R. M., Salunkhe, P., Godzik, A., and Reed, J. C. (2006) Identification and characterization of a novel bacterial virulence factor that shares homology with mammalian Toll/interleukin-1 receptor family proteins. Infect. Immun. 74, 594-601
    • (2006) Infect. Immun. , vol.74 , pp. 594-601
    • Newman, R.M.1    Salunkhe, P.2    Godzik, A.3    Reed, J.C.4
  • 28
    • 33947356714 scopus 로고    scopus 로고
    • Characterization of a TIR-like protein from Paracoccus denitrificans
    • Pascual, J., Low, L. Y., Mukasa, T., and Reed, J. C. (2007) Characterization of a TIR-like protein from Paracoccus denitrificans. Biochem. Biophys. Res. Commun. 356, 481-486
    • (2007) Biochem. Biophys. Res. Commun. , vol.356 , pp. 481-486
    • Pascual, J.1    Low, L.Y.2    Mukasa, T.3    Reed, J.C.4
  • 29
    • 0026331267 scopus 로고
    • X-ray structure of the GCN4 leucine zipper, a two-stranded, parallel coiled coil
    • O'Shea, E. K., Klemm, J. D., Kim, P. S., and Alber, T. (1991) X-ray structure of the GCN4 leucine zipper, a two-stranded, parallel coiled coil. Science 254, 539-544
    • (1991) Science , vol.254 , pp. 539-544
    • O'Shea, E.K.1    Klemm, J.D.2    Kim, P.S.3    Alber, T.4
  • 30
    • 3042548183 scopus 로고    scopus 로고
    • Toll-like receptor 9-dependent and -independent dendritic cell activation by chromatin-immunoglobulin G complexes
    • Boulé, M. W., Broughton, C., Mackay, F., Akira, S., Marshak-Rothstein, A., and Rifkin, I. R. (2004) Toll-like receptor 9-dependent and -independent dendritic cell activation by chromatin-immunoglobulin G complexes. J. Exp. Med. 199, 1631-1640
    • (2004) J. Exp. Med. , vol.199 , pp. 1631-1640
    • Boulé, M.W.1    Broughton, C.2    Mackay, F.3    Akira, S.4    Marshak-Rothstein, A.5    Rifkin, I.R.6
  • 31
    • 25444443335 scopus 로고    scopus 로고
    • RNA released from necrotic synovial fluid cells activates rheumatoid arthritis synovial fibroblasts via Toll-like receptor 3
    • Brentano, F., Schorr, O., Gay, R. E., Gay, S., and Kyburz, D. (2005) RNA released from necrotic synovial fluid cells activates rheumatoid arthritis synovial fibroblasts via Toll-like receptor 3. Arthritis Rheum. 52, 2656-2665
    • (2005) Arthritis Rheum. , vol.52 , pp. 2656-2665
    • Brentano, F.1    Schorr, O.2    Gay, R.E.3    Gay, S.4    Kyburz, D.5
  • 32
    • 33947545388 scopus 로고    scopus 로고
    • The Toll-like receptor adaptor proteins MyD88 and Mal/TIRAP contribute to the inflammatory and destructive processes in a human model of rheumatoid arthritis
    • Sacre, S. M., Andreakos, E., Kiriakidis, S., Amjadi, P., Lundberg, A., Giddins, G., Feldmann, M., Brennan, F., and Foxwell, B. M. (2007) The Toll-like receptor adaptor proteins MyD88 and Mal/TIRAP contribute to the inflammatory and destructive processes in a human model of rheumatoid arthritis. Am. J. Pathol. 170, 518-525
    • (2007) Am. J. Pathol. , vol.170 , pp. 518-525
    • Sacre, S.M.1    Andreakos, E.2    Kiriakidis, S.3    Amjadi, P.4    Lundberg, A.5    Giddins, G.6    Feldmann, M.7    Brennan, F.8    Foxwell, B.M.9
  • 33
    • 33746747096 scopus 로고    scopus 로고
    • MyD88-dependent IL-1 receptor signaling is essential for gouty inflammation stimulated by monosodium urate crystals
    • Chen, C. J., Shi, Y., Hearn, A., Fitzgerald, K., Golenbock, D., Reed, G., Akira, S., and Rock, K. L. (2006) MyD88-dependent IL-1 receptor signaling is essential for gouty inflammation stimulated by monosodium urate crystals. J. Clin. Invest. 116, 2262-2271
    • (2006) J. Clin. Invest. , vol.116 , pp. 2262-2271
    • Chen, C.J.1    Shi, Y.2    Hearn, A.3    Fitzgerald, K.4    Golenbock, D.5    Reed, G.6    Akira, S.7    Rock, K.L.8
  • 34
    • 69749101103 scopus 로고    scopus 로고
    • Microbial TIR domains: Not necessarily agents of subversion?
    • Spear, A. M., Loman, N. J., Atkins, H. S., and Pallen, M. J. (2009) Microbial TIR domains: not necessarily agents of subversion? Trends Microbiol. 17, 393-398
    • (2009) Trends Microbiol. , vol.17 , pp. 393-398
    • Spear, A.M.1    Loman, N.J.2    Atkins, H.S.3    Pallen, M.J.4
  • 36
    • 0034532379 scopus 로고    scopus 로고
    • Dominant negative MyD88 proteins inhibit interleukin-1β /interferon-γ-mediated induction of nuclear factor κB-dependent nitrite production and apoptosis in beta cells
    • Dupraz, P., Cottet, S., Hamburger, F., Dolci, W., Felley-Bosco, E., and Thorens, B. (2000) Dominant negative MyD88 proteins inhibit interleukin-1β /interferon-γ-mediated induction of nuclear factor κB-dependent nitrite production and apoptosis in beta cells. J. Biol. Chem. 275, 37672-37678
    • (2000) J. Biol. Chem. , vol.275 , pp. 37672-37678
    • Dupraz, P.1    Cottet, S.2    Hamburger, F.3    Dolci, W.4    Felley-Bosco, E.5    Thorens, B.6
  • 38
    • 70349324347 scopus 로고    scopus 로고
    • MyD88 adaptor-like is not essential for TLR2 signaling and inhibits signaling by TLR3
    • Kenny, E. F., Talbot, S., Gong, M., Golenbock, D. T., Bryant, C. E., and O'Neill, L. A. (2009) MyD88 adaptor-like is not essential for TLR2 signaling and inhibits signaling by TLR3. J. Immunol. 183, 3642-3651
    • (2009) J. Immunol. , vol.183 , pp. 3642-3651
    • Kenny, E.F.1    Talbot, S.2    Gong, M.3    Golenbock, D.T.4    Bryant, C.E.5    O'Neill, L.A.6
  • 41
    • 33646908228 scopus 로고    scopus 로고
    • Phosphoinositide-mediated adaptor recruitment controls Toll-like receptor signaling
    • Kagan, J. C., and Medzhitov, R. (2006) Phosphoinositide-mediated adaptor recruitment controls Toll-like receptor signaling. Cell 125, 943-955
    • (2006) Cell , vol.125 , pp. 943-955
    • Kagan, J.C.1    Medzhitov, R.2


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