Molecular mechanisms for the subversion of MyD88 signaling by TcpC from virulent uropathogenic Escherichia coli

Proceedings of the National Academy of Sciences of the United States of America

Volumn 110, Issue 17, 2013, Pages 6985-6990

  Snyder, Greg A ^a   Cirl, Christine ^b   Jiang, Jiansheng ^a   Chen, Kang ^c   Waldhuber, Anna ^b   Smith, Patrick ^a   Römmler, Franziska ^b   Snyder, Nathaniel ^a   Fresquez, Theresa ^a   Dürr, Susanne ^b   Tjandra, Nico ^c   Miethke, Thomas ^b   Xiao, Tsan Sam ^a  

^a NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^b TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^c NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

Author keywords

Bacterial pathogens; Innate immune cells

Indexed keywords

MYELOID DIFFERENTIATION FACTOR 88; PROTEIN C; TOLL LIKE RECEPTOR; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR CONTAINING PROTEIN C; UNCLASSIFIED DRUG; VIRULENCE FACTOR;

ARTICLE; BACTERIAL VIRULENCE; CRYSTAL STRUCTURE; CYTOKINE PRODUCTION; GENE MUTATION; IMMUNOSUPPRESSIVE TREATMENT; MOLECULAR MECHANICS; NONHUMAN; PREDICTIVE VALUE; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; STRUCTURE ANALYSIS; SURFACE PROPERTY; UROPATHOGENIC ESCHERICHIA COLI;

CRYSTALLOGRAPHY; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; HUMANS; IMMUNITY, INNATE; LUCIFERASES; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, MOLECULAR; MOLECULAR DYNAMICS SIMULATION; MUTATION; MYELOID DIFFERENTIATION FACTOR 88; PROTEIN CONFORMATION; RECEPTORS, INTERLEUKIN-1; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTORS; VIRULENCE FACTORS;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI;

EID: 84876844854     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1215770110     Document Type: Article

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