Structural and functional evidence for the role of the TLR2 DD loop in TLR1/TLR2 heterodimerization and signaling

Journal of Biological Chemistry

Volumn 281, Issue 40, 2006, Pages 30132-30142

  Gautam, Jitendra K ^a   Ashish, ^b   Comeau, Laurey D ^a   Krueger, Joanna K ^b   Smith Jr , Michael F ^a  

^a UNIVERSITY OF VIRGINIA HEALTH SYSTEM   (United States)

^b UNIVERSITY OF NORTH CAROLINA AT CHARLOTTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HETERODIMERIZATION; PROTEIN-PROTEIN INTERACTIONS; TOLL-LIKE RECEPTORS (TLRS);

BIOCHEMISTRY; CYTOLOGY; DIMERIZATION; MEDICAL APPLICATIONS; MUTAGENESIS; PROTEINS;

BIOLOGICAL MATERIALS;

ALANINE; AMINO ACID; ARGININE; CYTOKINE; HETERODIMER; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1 RECEPTOR; LEUCINE; TOLL LIKE RECEPTOR;

ARTICLE; DIMERIZATION; GENE EXPRESSION; GENE MUTATION; HOST RESISTANCE; MUTAGENESIS; MUTANT; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; WILD TYPE;

AMINO ACID SUBSTITUTION; CELL LINE; COMPUTATIONAL BIOLOGY; DIMERIZATION; HUMANS; MUTAGENESIS, SITE-DIRECTED; NF-KAPPA B; POINT MUTATION; PROTEIN STRUCTURE, TERTIARY; SIGNAL TRANSDUCTION; STRUCTURE-ACTIVITY RELATIONSHIP; TOLL-LIKE RECEPTOR 1; TOLL-LIKE RECEPTOR 2;

EID: 33749574498     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M602057200     Document Type: Article

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