Mechanism of bacterial interference with TLR4 signaling by brucella toll/interleukin-1 receptor domain-containing protein TcpB

Journal of Biological Chemistry

Volumn 289, Issue 2, 2014, Pages 654-668

  Alaidarous, Mohammed ^a   Ve, Thomas ^a   Casey, Lachlan W ^a   Valkov, Eugene ^a,b   Ericsson, Daniel J ^a   Ullah, M Obayed ^a   Schembri, Mark A ^a   Mansell, Ashley ^c   Sweet, Matthew J ^a   Kobe, Bostjan ^a  

^a UNIVERSITY OF QUEENSLAND   (Australia)

^b MONASH UNIVERSITY   (Australia)

^c MEDICAL RESEARCH COUNCIL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

DIMERS;

BRUCELLA; DOMAIN-CONTAINING PROTEINS; HOST MOLECULES; RECEPTOR DOMAINS; TOLL-LIKE RECEPTORS;

PROTEINS;

DIMER; INTERLEUKIN 1 RECEPTOR; MYELOID DIFFERENTIATION FACTOR 88; MYELOID DIFFERENTIATION FACTOR 88 ADAPTOR LIKE PROTEIN; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; UNCLASSIFIED DRUG;

ANTIBIOSIS; ARTICLE; BACTERIAL VIRULENCE; BIOPHYSICS; BRUCELLA MELITENSIS; CONTROLLED STUDY; CRYSTAL STRUCTURE; CYTOKINE RELEASE; DIMERIZATION; ENZYME ACTIVATION; HOST PATHOGEN INTERACTION; IMMUNOPRECIPITATION; INNATE IMMUNITY; MUTAGENESIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; TRANSCRIPTION INITIATION;

ADAPTOR PROTEINS; INNATE IMMUNITY; PROTEIN STRUCTURE; TOLL IL-1 RECEPTOR (TIR) DOMAIN; TOLL-LIKE RECEPTORS (TLR);

AMINO ACID SEQUENCE; BACTERIAL PROTEINS; BINDING SITES; BRUCELLA MELITENSIS; HEK293 CELLS; HUMANS; IMMUNOBLOTTING; IMMUNOPRECIPITATION; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTATION; MYELIN AND LYMPHOCYTE-ASSOCIATED PROTEOLIPID PROTEINS; MYELOID DIFFERENTIATION FACTOR 88; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN MULTIMERIZATION; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, INTERLEUKIN-1; SCATTERING, SMALL ANGLE; SEQUENCE HOMOLOGY, AMINO ACID; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTOR 4; VIRULENCE FACTORS; X-RAY DIFFRACTION;

EID: 84891946034     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.523274     Document Type: Article

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