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Volumn 22, Issue 4, 2017, Pages 497-511

Molecular mechanisms underlying noncoding risk variations in psychiatric genetic studies

Author keywords

[No Author keywords available]

Indexed keywords

BIOINFORMATICS; BIPOLAR DISORDER; ENHANCER REGION; GENE EXPRESSION; GENE LOCUS; GENETIC ASSOCIATION; GENETIC RISK; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; GENOME-WIDE ASSOCIATION STUDY; HUMAN; MENTAL DISEASE; NEUROPATHOLOGY; NONHUMAN; PATHOGENESIS; PATHOPHYSIOLOGY; PREDICTION; PROMOTER REGION; QUANTITATIVE TRAIT LOCUS; REVIEW; SCHIZOPHRENIA; SINGLE NUCLEOTIDE POLYMORPHISM; TRANSCRIPTOMICS; GENETIC PREDISPOSITION; GENETIC VARIATION; GENETICS; GENOME; GENOMICS; MENTAL HEALTH; METABOLISM; PROCEDURES; RISK FACTOR;

EID: 85007605391     PISSN: 13594184     EISSN: 14765578     Source Type: Journal    
DOI: 10.1038/mp.2016.241     Document Type: Review
Times cited : (34)

References (171)
  • 1
    • 2542498720 scopus 로고    scopus 로고
    • Prevalence, severity, and unmet need for treatment of mental disorders in the World Health Organization World Mental Health Surveys
    • Demyttenaere K, Bruffaerts R, Posada-Villa J, Gasquet I, Kovess V, Lepine JP et al. Prevalence, severity, and unmet need for treatment of mental disorders in the World Health Organization World Mental Health Surveys. JAMA 2004; 291: 2581-2590.
    • (2004) JAMA , vol.291 , pp. 2581-2590
    • Demyttenaere, K.1    Bruffaerts, R.2    Posada-Villa, J.3    Gasquet, I.4    Kovess, V.5    Lepine, J.P.6
  • 2
    • 0242354132 scopus 로고    scopus 로고
    • Family, twin, and adoption studies of bipolar disorder
    • Smoller JW, Finn CT. Family, twin, and adoption studies of bipolar disorder. Am J Med Genet C Semin Med Genet 2003; 123C: 48-58.
    • (2003) Am J Med Genet C Semin Med Genet , vol.123 C , pp. 48-58
    • Smoller, J.W.1    Finn, C.T.2
  • 3
    • 0344305525 scopus 로고    scopus 로고
    • Schizophrenia as a complex trait: Evidence from a meta-analysis of twin studies
    • Sullivan PF, Kendler KS, Neale MC. Schizophrenia as a complex trait: evidence from a meta-analysis of twin studies. Arch Gen Psychiatry 2003; 60: 1187-1192.
    • (2003) Arch Gen Psychiatry , vol.60 , pp. 1187-1192
    • Sullivan, P.F.1    Kendler, K.S.2    Neale, M.C.3
  • 4
    • 0027432603 scopus 로고
    • Continuity and discontinuity of affective disorders and schizophrenia Results of a controlled family study
    • Maier W, Lichtermann D, Minges J, Hallmayer J, Heun R, Benkert O et al. Continuity and discontinuity of affective disorders and schizophrenia. Results of a controlled family study. Arch Gen Psychiatry 1993; 50: 871-883.
    • (1993) Arch Gen Psychiatry , vol.50 , pp. 871-883
    • Maier, W.1    Lichtermann, D.2    Minges, J.3    Hallmayer, J.4    Heun, R.5    Benkert, O.6
  • 5
    • 84876296688 scopus 로고    scopus 로고
    • Identification of risk loci with shared effects on five major psychiatric disorders: A genome-wide analysis
    • Cross-Disorder Group of the Psychiatric Genomics Consortium
    • Cross-Disorder Group of the Psychiatric Genomics Consortium. Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis. Lancet 2013; 381: 1371-1379.
    • (2013) Lancet , vol.381 , pp. 1371-1379
  • 6
    • 84938379545 scopus 로고    scopus 로고
    • Sparse whole-genome sequencing identifies two loci for major depressive disorder
    • Converge Consortium
    • Converge Consortium. Sparse whole-genome sequencing identifies two loci for major depressive disorder. Nature 2015; 523: 588-591.
    • (2015) Nature , vol.523 , pp. 588-591
  • 7
    • 80053385384 scopus 로고    scopus 로고
    • Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4
    • Psychiatric GWAS Consortium Bipolar Disorder Working Group
    • Psychiatric GWAS Consortium Bipolar Disorder Working Group. Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4. Nat Genet 2011; 43: 977-983.
    • (2011) Nat Genet , vol.43 , pp. 977-983
  • 8
    • 84904804929 scopus 로고    scopus 로고
    • Biological insights from 108 schizophrenia-associated genetic loci
    • Schizophrenia Working Group of the Psychiatric Genomics Consortium
    • Schizophrenia Working Group of the Psychiatric Genomics Consortium. Biological insights from 108 schizophrenia-associated genetic loci. Nature 2014; 511: 421-427.
    • (2014) Nature , vol.511 , pp. 421-427
  • 9
    • 67349112868 scopus 로고    scopus 로고
    • Common genetic variants on 5p14.1 associate with autism spectrum disorders
    • Wang K, Zhang H, Ma D, Bucan M, Glessner JT, Abrahams BS et al. Common genetic variants on 5p14.1 associate with autism spectrum disorders. Nature 2009; 459: 528-533.
    • (2009) Nature , vol.459 , pp. 528-533
    • Wang, K.1    Zhang, H.2    Ma, D.3    Bucan, M.4    Glessner, J.T.5    Abrahams, B.S.6
  • 10
    • 84980347551 scopus 로고    scopus 로고
    • Identification of 15 genetic loci associated with risk of major depression in individuals of European descent
    • Hyde CL, Nagle MW, Tian C, Chen X, Paciga SA, Wendland JR et al. Identification of 15 genetic loci associated with risk of major depression in individuals of European descent. Nat Genet 2016; 48: 1031-1036.
    • (2016) Nat Genet , vol.48 , pp. 1031-1036
    • Hyde, C.L.1    Nagle, M.W.2    Tian, C.3    Chen, X.4    Paciga, S.A.5    Wendland, J.R.6
  • 11
    • 84856225986 scopus 로고    scopus 로고
    • De novo CNV analysis implicates specific abnormalities of postsynaptic signalling complexes in the pathogenesis of schizophrenia
    • Kirov G, Pocklington AJ, Holmans P, Ivanov D, Ikeda M, Ruderfer D et al. De novo CNV analysis implicates specific abnormalities of postsynaptic signalling complexes in the pathogenesis of schizophrenia. Mol Psychiatry 2012; 17: 142-153.
    • (2012) Mol Psychiatry , vol.17 , pp. 142-153
    • Kirov, G.1    Pocklington, A.J.2    Holmans, P.3    Ivanov, D.4    Ikeda, M.5    Ruderfer, D.6
  • 14
    • 68449086236 scopus 로고    scopus 로고
    • Common polygenic variation contributes to risk of schizophrenia and bipolar disorder
    • International Schizophrenia Consortium
    • International Schizophrenia Consortium, Purcell SM, Wray NR, Stone JL, Visscher PM, O'Donovan MC et al. Common polygenic variation contributes to risk of schizophrenia and bipolar disorder. Nature 2009; 460: 748-752.
    • (2009) Nature , vol.460 , pp. 748-752
    • Purcell, S.M.1    Wray, N.R.2    Stone, J.L.3    Visscher, P.M.4    O'Donovan, M.C.5
  • 15
    • 84923077204 scopus 로고    scopus 로고
    • Psychiatric genome-wide association study analyses implicate neuronal, immune and histone pathways
    • Network Pathway Analysis Subgroup of Psychiatric Genomics Consortium
    • Network Pathway Analysis Subgroup of Psychiatric Genomics Consortium. Psychiatric genome-wide association study analyses implicate neuronal, immune and histone pathways. Nat Neurosci 2015; 18: 199-209.
    • (2015) Nat Neurosci , vol.18 , pp. 199-209
  • 16
    • 84912091480 scopus 로고    scopus 로고
    • Translating human genetics into novel treatment targets for schizophrenia
    • Schubert CR, Xi HS, Wendland JR, O'Donnell P. Translating human genetics into novel treatment targets for schizophrenia. Neuron 2014; 84: 537-541.
    • (2014) Neuron , vol.84 , pp. 537-541
    • Schubert, C.R.1    Xi, H.S.2    Wendland, J.R.3    O'Donnell, P.4
  • 17
    • 84964388798 scopus 로고    scopus 로고
    • Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses
    • Okbay A, Baselmans BM, De Neve JE, Turley P, Nivard MG, Fontana MA et al. Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses. Nat Genet 2016; 48: 624-633.
    • (2016) Nat Genet , vol.48 , pp. 624-633
    • Okbay, A.1    Baselmans, B.M.2    De Neve, J.E.3    Turley, P.4    Nivard, M.G.5    Fontana, M.A.6
  • 18
    • 85014343531 scopus 로고    scopus 로고
    • Genome-wide association study of 40,000 individuals identifies two novel loci associated with bipolar disorder
    • Hou L, Bergen SE, Akula N, Song J, Hultman CM, Landen M et al. Genome-wide association study of 40,000 individuals identifies two novel loci associated with bipolar disorder. Hum Mol Genet 2016; doi: 10.1093/hmg/ddw181.
    • (2016) Hum Mol Genet
    • Hou, L.1    Bergen, S.E.2    Akula, N.3    Song, J.4    Hultman, C.M.5    Landen, M.6
  • 19
    • 84872877090 scopus 로고    scopus 로고
    • History of the discovery of the antipsychotic dopamine D2 receptor: A basis for the dopamine hypothesis of schizophrenia
    • Madras BK. History of the discovery of the antipsychotic dopamine D2 receptor: a basis for the dopamine hypothesis of schizophrenia. J Hist Neurosci 2013; 22: 62-78.
    • (2013) J Hist Neurosci , vol.22 , pp. 62-78
    • Madras, B.K.1
  • 20
    • 84962233946 scopus 로고    scopus 로고
    • Rare loss-offunction variants in SETD1A are associated with schizophrenia and developmental disorders
    • Singh T, Kurki MI, Curtis D, Purcell SM, Crooks L, McRae J et al. Rare loss-offunction variants in SETD1A are associated with schizophrenia and developmental disorders. Nat Neurosci 2016; 19: 571-577.
    • (2016) Nat Neurosci , vol.19 , pp. 571-577
    • Singh, T.1    Kurki, M.I.2    Curtis, D.3    Purcell, S.M.4    Crooks, L.5    McRae, J.6
  • 21
    • 84960469255 scopus 로고    scopus 로고
    • De novo synonymous mutations in regulatory elements contribute to the genetic etiology of autism and schizophrenia
    • Takata A, Ionita-Laza I, Gogos JA, Xu B, Karayiorgou M. De novo synonymous mutations in regulatory elements contribute to the genetic etiology of autism and schizophrenia. Neuron 2016; 89: 940-947.
    • (2016) Neuron , vol.89 , pp. 940-947
    • Takata, A.1    Ionita-Laza, I.2    Gogos, J.A.3    Xu, B.4    Karayiorgou, M.5
  • 22
    • 84900986803 scopus 로고    scopus 로고
    • Loss-of-function variants in schizophrenia risk and SETD1A as a candidate susceptibility gene
    • Takata A, Xu B, Ionita-Laza I, Roos JL, Gogos JA, Karayiorgou M. Loss-of-function variants in schizophrenia risk and SETD1A as a candidate susceptibility gene. Neuron 2014; 82: 773-780.
    • (2014) Neuron , vol.82 , pp. 773-780
    • Takata, A.1    Xu, B.2    Ionita-Laza, I.3    Roos, J.L.4    Gogos, J.A.5    Karayiorgou, M.6
  • 23
  • 25
    • 84918818374 scopus 로고    scopus 로고
    • Progressive reduction in cortical thickness as psychosis develops: A multisite longitudinal neuroimaging study of youth at elevated clinical risk
    • Cannon TD, Chung Y, He G, Sun D, Jacobson A, van Erp TG et al. Progressive reduction in cortical thickness as psychosis develops: a multisite longitudinal neuroimaging study of youth at elevated clinical risk. Biol Psychiatry 2015; 77: 147-157.
    • (2015) Biol Psychiatry , vol.77 , pp. 147-157
    • Cannon, T.D.1    Chung, Y.2    He, G.3    Sun, D.4    Jacobson, A.5    Van Erp, T.G.6
  • 26
    • 84884288041 scopus 로고    scopus 로고
    • Dendritic spine pathology in schizophrenia
    • Glausier JR, Lewis DA. Dendritic spine pathology in schizophrenia. Neuroscience 2013; 251: 90-107.
    • (2013) Neuroscience , vol.251 , pp. 90-107
    • Glausier, J.R.1    Lewis, D.A.2
  • 28
    • 50449089356 scopus 로고    scopus 로고
    • Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder
    • Ferreira MA, O'Donovan MC, Meng YA, Jones IR, Ruderfer DM, Jones L et al. Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder. Nat Genet 2008; 40: 1056-1058.
    • (2008) Nat Genet , vol.40 , pp. 1056-1058
    • Ferreira, M.A.1    O'Donovan, M.C.2    Meng, Y.A.3    Jones, I.R.4    Ruderfer, D.M.5    Jones, L.6
  • 29
    • 84873058959 scopus 로고    scopus 로고
    • Genomewide association study meta-analysis of European and Asian-ancestry samples identifies three novel loci associated with bipolar disorder
    • Chen DT, Jiang X, Akula N, Shugart YY, Wendland JR, Steele CJ et al. Genomewide association study meta-analysis of European and Asian-ancestry samples identifies three novel loci associated with bipolar disorder. Mol Psychiatry 2013; 18: 195-205.
    • (2013) Mol Psychiatry , vol.18 , pp. 195-205
    • Chen, D.T.1    Jiang, X.2    Akula, N.3    Shugart, Y.Y.4    Wendland, J.R.5    Steele, C.J.6
  • 30
    • 84949817972 scopus 로고    scopus 로고
    • A loss-offunction variant in a minor isoform of ANK3 protects against bipolar disorder and schizophrenia
    • Hughes T, Hansson L, Sonderby IE, Athanasiu L, Zuber V, Tesli M et al. A loss-offunction variant in a minor isoform of ANK3 protects against bipolar disorder and schizophrenia. Biol Psychiatry 2016; 80: 323-330.
    • (2016) Biol Psychiatry , vol.80 , pp. 323-330
    • Hughes, T.1    Hansson, L.2    Sonderby, I.E.3    Athanasiu, L.4    Zuber, V.5    Tesli, M.6
  • 31
    • 84881187768 scopus 로고    scopus 로고
    • Cisacting regulation of brain-specific ANK3 gene expression by a genetic variant associated with bipolar disorder
    • Rueckert EH, Barker D, Ruderfer D, Bergen SE, O'Dushlaine C, Luce CJ et al. Cisacting regulation of brain-specific ANK3 gene expression by a genetic variant associated with bipolar disorder. Mol Psychiatry 2013; 18: 922-929.
    • (2013) Mol Psychiatry , vol.18 , pp. 922-929
    • Rueckert, E.H.1    Barker, D.2    Ruderfer, D.3    Bergen, S.E.4    O'Dushlaine, C.5    Luce, C.J.6
  • 32
    • 80055015161 scopus 로고    scopus 로고
    • Temporal dynamics and genetic control of transcription in the human prefrontal cortex
    • Colantuoni C, Lipska BK, Ye T, Hyde TM, Tao R, Leek JT et al. Temporal dynamics and genetic control of transcription in the human prefrontal cortex. Nature 2011; 478: 519-523.
    • (2011) Nature , vol.478 , pp. 519-523
    • Colantuoni, C.1    Lipska, B.K.2    Ye, T.3    Hyde, T.M.4    Tao, R.5    Leek, J.T.6
  • 33
    • 78650443750 scopus 로고    scopus 로고
    • Genetic neuropathology of schizophrenia: New approaches to an old question and new uses for postmortem human brains
    • Kleinman JE, Law AJ, Lipska BK, Hyde TM, Ellis JK, Harrison PJ et al. Genetic neuropathology of schizophrenia: new approaches to an old question and new uses for postmortem human brains. Biol Psychiatry 2011; 69: 140-145.
    • (2011) Biol Psychiatry , vol.69 , pp. 140-145
    • Kleinman, J.E.1    Law, A.J.2    Lipska, B.K.3    Hyde, T.M.4    Ellis, J.K.5    Harrison, P.J.6
  • 35
    • 84878682420 scopus 로고    scopus 로고
    • The Genotype-Tissue Expression (GTEx) project
    • GTEx Consortium
    • GTEx Consortium. The Genotype-Tissue Expression (GTEx) project. Nat Genet 2013; 45: 580-585.
    • (2013) Nat Genet , vol.45 , pp. 580-585
  • 36
    • 84929001104 scopus 로고    scopus 로고
    • Human genomics the Genotype-Tissue Expression (GTEx) pilot analysis: Multitissue gene regulation in humans
    • GTEx Consortium
    • GTEx Consortium. Human genomics. The Genotype-Tissue Expression (GTEx) pilot analysis: multitissue gene regulation in humans. Science 2015; 348: 648-660.
    • (2015) Science , vol.348 , pp. 648-660
  • 37
    • 80053572217 scopus 로고    scopus 로고
    • Quality control parameters on a large dataset of regionally dissected human control brains for whole genome expression studies
    • Trabzuni D, Ryten M, Walker R, Smith C, Imran S, Ramasamy A et al. Quality control parameters on a large dataset of regionally dissected human control brains for whole genome expression studies. J Neurochem 2011; 119: 275-282.
    • (2011) J Neurochem , vol.119 , pp. 275-282
    • Trabzuni, D.1    Ryten, M.2    Walker, R.3    Smith, C.4    Imran, S.5    Ramasamy, A.6
  • 38
    • 84921750431 scopus 로고    scopus 로고
    • Genetic variability in the regulation of gene expression in ten regions of the human brain
    • Ramasamy A, Trabzuni D, Guelfi S, Varghese V, Smith C, Walker R et al. Genetic variability in the regulation of gene expression in ten regions of the human brain. Nat Neurosci 2014; 17: 1418-1428.
    • (2014) Nat Neurosci , vol.17 , pp. 1418-1428
    • Ramasamy, A.1    Trabzuni, D.2    Guelfi, S.3    Varghese, V.4    Smith, C.5    Walker, R.6
  • 40
    • 58149163446 scopus 로고    scopus 로고
    • Tissuespecific genetic control of splicing: Implications for the study of complex traits
    • Heinzen EL, Ge D, Cronin KD, Maia JM, Shianna KV, Gabriel WN et al. Tissuespecific genetic control of splicing: implications for the study of complex traits. PLoS Biol 2008; 6: e1.
    • (2008) PLoS Biol , vol.6 , pp. e1
    • Heinzen, E.L.1    Ge, D.2    Cronin, K.D.3    Maia, J.M.4    Shianna, K.V.5    Gabriel, W.N.6
  • 41
    • 77955654595 scopus 로고    scopus 로고
    • Whole-genome association mapping of gene expression in the human prefrontal cortex
    • Liu C, Cheng L, Badner JA, Zhang D, Craig DW, Redman M et al. Whole-genome association mapping of gene expression in the human prefrontal cortex. Mol Psychiatry 2010; 15: 779-784.
    • (2010) Mol Psychiatry , vol.15 , pp. 779-784
    • Liu, C.1    Cheng, L.2    Badner, J.A.3    Zhang, D.4    Craig, D.W.5    Redman, M.6
  • 44
    • 84864066707 scopus 로고    scopus 로고
    • Brain expression genome-wide association study (eGWAS) identifies human disease-associated variants
    • Zou F, Chai HS, Younkin CS, Allen M, Crook J, Pankratz VS et al. Brain expression genome-wide association study (eGWAS) identifies human disease-associated variants. PLoS Genet 2012; 8: e1002707.
    • (2012) PLoS Genet , vol.8 , pp. e1002707
    • Zou, F.1    Chai, H.S.2    Younkin, C.S.3    Allen, M.4    Crook, J.5    Pankratz, V.S.6
  • 46
    • 34848914038 scopus 로고    scopus 로고
    • Capturing heterogeneity in gene expression studies by surrogate variable analysis
    • Leek JT, Storey JD. Capturing heterogeneity in gene expression studies by surrogate variable analysis. PLoS Genet 2007; 3: 1724-1735.
    • (2007) PLoS Genet , vol.3 , pp. 1724-1735
    • Leek, J.T.1    Storey, J.D.2
  • 47
    • 33845432928 scopus 로고    scopus 로고
    • Adjusting batch effects in microarray expression data using empirical Bayes methods
    • Johnson WE, Li C, Rabinovic A. Adjusting batch effects in microarray expression data using empirical Bayes methods. Biostatistics 2007; 8: 118-127.
    • (2007) Biostatistics , vol.8 , pp. 118-127
    • Johnson, W.E.1    Li, C.2    Rabinovic, A.3
  • 48
    • 84876907931 scopus 로고    scopus 로고
    • Integrated systems approach identifies genetic nodes and networks in lateonset Alzheimer's disease
    • Zhang B, Gaiteri C, Bodea LG, Wang Z, McElwee J, Podtelezhnikov AA et al. Integrated systems approach identifies genetic nodes and networks in lateonset Alzheimer's disease. Cell 2013; 153: 707-720.
    • (2013) Cell , vol.153 , pp. 707-720
    • Zhang, B.1    Gaiteri, C.2    Bodea, L.G.3    Wang, Z.4    McElwee, J.5    Podtelezhnikov, A.A.6
  • 49
    • 66749174141 scopus 로고    scopus 로고
    • A primate-specific, brain isoform of KCNH2 affects cortical physiology, cognition, neuronal repolarization and risk of schizophrenia
    • Huffaker SJ, Chen J, Nicodemus KK, Sambataro F, Yang F, Mattay V et al. A primate-specific, brain isoform of KCNH2 affects cortical physiology, cognition, neuronal repolarization and risk of schizophrenia. Nat Med 2009; 15: 509-518.
    • (2009) Nat Med , vol.15 , pp. 509-518
    • Huffaker, S.J.1    Chen, J.2    Nicodemus, K.K.3    Sambataro, F.4    Yang, F.5    Mattay, V.6
  • 50
    • 33646240854 scopus 로고    scopus 로고
    • Neuregulin 1 transcripts are differentially expressed in schizophrenia and regulated by 5' SNPs associated with the disease
    • Law AJ, Lipska BK, Weickert CS, Hyde TM, Straub RE, Hashimoto R et al. Neuregulin 1 transcripts are differentially expressed in schizophrenia and regulated by 5' SNPs associated with the disease. Proc Natl Acad Sci USA 2006; 103: 6747-6752.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 6747-6752
    • Law, A.J.1    Lipska, B.K.2    Weickert, C.S.3    Hyde, T.M.4    Straub, R.E.5    Hashimoto, R.6
  • 51
    • 84966657282 scopus 로고    scopus 로고
    • A human-specific AS3MT isoform and BORCS7 are molecular risk factors in the 10q24.32 schizophreniaassociated locus
    • Li M, Jaffe AE, Straub RE, Tao R, Shin JH, Wang Y et al. A human-specific AS3MT isoform and BORCS7 are molecular risk factors in the 10q24.32 schizophreniaassociated locus. Nat Med 2016; 22: 649-656.
    • (2016) Nat Med , vol.22 , pp. 649-656
    • Li, M.1    Jaffe, A.E.2    Straub, R.E.3    Tao, R.4    Shin, J.H.5    Wang, Y.6
  • 52
    • 84907743604 scopus 로고    scopus 로고
    • Expression of ZNF804A in human brain and alterations in schizophrenia, bipolar disorder, and major depressive disorder: A novel transcript fetally regulated by the psychosis risk variant rs1344706
    • Tao R, Cousijn H, Jaffe AE, Burnet PW, Edwards F, Eastwood SL et al. Expression of ZNF804A in human brain and alterations in schizophrenia, bipolar disorder, and major depressive disorder: a novel transcript fetally regulated by the psychosis risk variant rs1344706. JAMA Psychiatry 2014; 71: 1112-1120.
    • (2014) JAMA Psychiatry , vol.71 , pp. 1112-1120
    • Tao, R.1    Cousijn, H.2    Jaffe, A.E.3    Burnet, P.W.4    Edwards, F.5    Eastwood, S.L.6
  • 53
    • 50449100461 scopus 로고    scopus 로고
    • Identification of loci associated with schizophrenia by genome-wide association and follow-up
    • O'Donovan MC, Craddock N, Norton N, Williams H, Peirce T, Moskvina V et al. Identification of loci associated with schizophrenia by genome-wide association and follow-up. Nat Genet 2008; 40: 1053-1055.
    • (2008) Nat Genet , vol.40 , pp. 1053-1055
    • O'Donovan, M.C.1    Craddock, N.2    Norton, N.3    Williams, H.4    Peirce, T.5    Moskvina, V.6
  • 54
    • 72949110176 scopus 로고    scopus 로고
    • Replication of association between schizophrenia and ZNF804A in the Irish Case-Control Study of Schizophrenia sample
    • Riley B, Thiselton D, Maher BS, Bigdeli T, Wormley B, McMichael GO et al. Replication of association between schizophrenia and ZNF804A in the Irish Case-Control Study of Schizophrenia sample. Mol Psychiatry 2010; 15: 29-37.
    • (2010) Mol Psychiatry , vol.15 , pp. 29-37
    • Riley, B.1    Thiselton, D.2    Maher, B.S.3    Bigdeli, T.4    Wormley, B.5    McMichael, G.O.6
  • 56
    • 79953034507 scopus 로고    scopus 로고
    • Fine mapping of ZNF804A and genome-wide significant evidence for its involvement in schizophrenia and bipolar disorder
    • Williams HJ, Norton N, Dwyer S, Moskvina V, Nikolov I, Carroll L et al. Fine mapping of ZNF804A and genome-wide significant evidence for its involvement in schizophrenia and bipolar disorder. Mol Psychiatry 2011; 16: 429-441.
    • (2011) Mol Psychiatry , vol.16 , pp. 429-441
    • Williams, H.J.1    Norton, N.2    Dwyer, S.3    Moskvina, V.4    Nikolov, I.5    Carroll, L.6
  • 57
    • 84891628682 scopus 로고    scopus 로고
    • Evidence of allelic imbalance in the schizophrenia susceptibility gene ZNF804A in human dorsolateral prefrontal cortex
    • Guella I, Sequeira A, Rollins B, Morgan L, Myers RM, Watson SJ et al. Evidence of allelic imbalance in the schizophrenia susceptibility gene ZNF804A in human dorsolateral prefrontal cortex. Schizophr Res 2014; 152: 111-116.
    • (2014) Schizophr Res , vol.152 , pp. 111-116
    • Guella, I.1    Sequeira, A.2    Rollins, B.3    Morgan, L.4    Myers, R.M.5    Watson, S.J.6
  • 58
    • 84895824395 scopus 로고    scopus 로고
    • Allelic imbalance associated with the schizophrenia risk SNP rs1344706 indicates a cis-acting variant in ZNF804A
    • Guella I, Vawter MP. Allelic imbalance associated with the schizophrenia risk SNP rs1344706 indicates a cis-acting variant in ZNF804A. Schizophr Res 2014; 153: 243-245.
    • (2014) Schizophr Res , vol.153 , pp. 243-245
    • Guella, I.1    Vawter, M.P.2
  • 59
    • 84871839909 scopus 로고    scopus 로고
    • Evidence that schizophrenia risk variation in the ZNF804A gene exerts its effects during fetal brain development
    • Hill MJ, Bray NJ. Evidence that schizophrenia risk variation in the ZNF804A gene exerts its effects during fetal brain development. Am J Psychiatry 2012; 169: 1301-1308.
    • (2012) Am J Psychiatry , vol.169 , pp. 1301-1308
    • Hill, M.J.1    Bray, N.J.2
  • 60
  • 61
    • 84961616869 scopus 로고    scopus 로고
    • BrainSeq: Neurogenomics to drive novel target discovery for neuropsychiatric disorders
    • BrainSeq: A Human Brain Genomics Consortium
    • BrainSeq: A Human Brain Genomics Consortium. BrainSeq: neurogenomics to drive novel target discovery for neuropsychiatric disorders. Neuron 2015; 88: 1078-1083.
    • (2015) Neuron , vol.88 , pp. 1078-1083
  • 64
    • 34547216747 scopus 로고    scopus 로고
    • Genetic variants regulating ORMDL3 expression contribute to the risk of childhood asthma
    • Moffatt MF, Kabesch M, Liang L, Dixon AL, Strachan D, Heath S et al. Genetic variants regulating ORMDL3 expression contribute to the risk of childhood asthma. Nature 2007; 448: 470-473.
    • (2007) Nature , vol.448 , pp. 470-473
    • Moffatt, M.F.1    Kabesch, M.2    Liang, L.3    Dixon, A.L.4    Strachan, D.5    Heath, S.6
  • 65
    • 45849117641 scopus 로고    scopus 로고
    • Statistical power of expression quantitative trait loci for mapping of complex trait loci in natural populations
    • Schliekelman P. Statistical power of expression quantitative trait loci for mapping of complex trait loci in natural populations. Genetics 2008; 178: 2201-2216.
    • (2008) Genetics , vol.178 , pp. 2201-2216
    • Schliekelman, P.1
  • 66
    • 84859888972 scopus 로고    scopus 로고
    • Statistical properties of interval mapping methods on quantitative trait loci location: Impact on QTL/ eQTL analyses
    • Wang X, Gilbert H, Moreno C, Filangi O, Elsen JM, Le Roy P. Statistical properties of interval mapping methods on quantitative trait loci location: impact on QTL/ eQTL analyses. BMC Genet 2012; 13: 29.
    • (2012) BMC Genet , vol.13 , pp. 29
    • Wang, X.1    Gilbert, H.2    Moreno, C.3    Filangi, O.4    Elsen, J.M.5    Le Roy, P.6
  • 67
    • 68949211709 scopus 로고    scopus 로고
    • Genetics of human gene expression: Mapping DNA variants that influence gene expression
    • Cheung VG, Spielman RS. Genetics of human gene expression: mapping DNA variants that influence gene expression. Nat Rev Genet 2009; 10: 595-604.
    • (2009) Nat Rev Genet , vol.10 , pp. 595-604
    • Cheung, V.G.1    Spielman, R.S.2
  • 68
    • 84885018609 scopus 로고    scopus 로고
    • Systematic identification of trans eQTLs as putative drivers of known disease associations
    • Westra HJ, Peters MJ, Esko T, Yaghootkar H, Schurmann C, Kettunen J et al. Systematic identification of trans eQTLs as putative drivers of known disease associations. Nat Genet 2013; 45: 1238-1243.
    • (2013) Nat Genet , vol.45 , pp. 1238-1243
    • Westra, H.J.1    Peters, M.J.2    Esko, T.3    Yaghootkar, H.4    Schurmann, C.5    Kettunen, J.6
  • 69
    • 80052322958 scopus 로고    scopus 로고
    • Trans-eQTLs reveal that independent genetic variants associated with a complex phenotype converge on intermediate genes, with a major role for the HLA
    • Fehrmann RS, Jansen RC, Veldink JH, Westra HJ, Arends D, Bonder MJ et al. Trans-eQTLs reveal that independent genetic variants associated with a complex phenotype converge on intermediate genes, with a major role for the HLA. PLoS Genet 2011; 7: e1002197.
    • (2011) PLoS Genet , vol.7 , pp. e1002197
    • Fehrmann, R.S.1    Jansen, R.C.2    Veldink, J.H.3    Westra, H.J.4    Arends, D.5    Bonder, M.J.6
  • 70
    • 84873517235 scopus 로고    scopus 로고
    • Genome-wide haplotype analysis of cis expression quantitative trait loci in monocytes
    • Garnier S, Truong V, Brocheton J, Zeller T, Rovital M, Wild PS et al. Genome-wide haplotype analysis of cis expression quantitative trait loci in monocytes. PLoS Genet 2013; 9: e1003240.
    • (2013) PLoS Genet , vol.9 , pp. e1003240
    • Garnier, S.1    Truong, V.2    Brocheton, J.3    Zeller, T.4    Rovital, M.5    Wild, P.S.6
  • 71
    • 84873489136 scopus 로고    scopus 로고
    • Human disease-associated genetic variation impacts large intergenic noncoding RNA expression
    • Kumar V, Westra HJ, Karjalainen J, Zhernakova DV, Esko T, Hrdlickova B et al. Human disease-associated genetic variation impacts large intergenic noncoding RNA expression. PLoS Genet 2013; 9: e1003201.
    • (2013) PLoS Genet , vol.9 , pp. e1003201
    • Kumar, V.1    Westra, H.J.2    Karjalainen, J.3    Zhernakova, D.V.4    Esko, T.5    Hrdlickova, B.6
  • 73
    • 79952256739 scopus 로고    scopus 로고
    • The architecture of gene regulatory variation across multiple human tissues: The MuTHER study
    • Nica AC, Parts L, Glass D, Nisbet J, Barrett A, Sekowska M et al. The architecture of gene regulatory variation across multiple human tissues: the MuTHER study. PLoS Genet 2011; 7: e1002003.
    • (2011) PLoS Genet , vol.7 , pp. e1002003
    • Nica, A.C.1    Parts, L.2    Glass, D.3    Nisbet, J.4    Barrett, A.5    Sekowska, M.6
  • 75
    • 84908553599 scopus 로고    scopus 로고
    • RNA-sequencing of the brain transcriptome implicates dysregulation of neuroplasticity, circadian rhythms and GTPase binding in bipolar disorder
    • Akula N, Barb J, Jiang X, Wendland JR, Choi KH, Sen SK et al. RNA-sequencing of the brain transcriptome implicates dysregulation of neuroplasticity, circadian rhythms and GTPase binding in bipolar disorder. Mol Psychiatry 2014; 19: 1179-1185.
    • (2014) Mol Psychiatry , vol.19 , pp. 1179-1185
    • Akula, N.1    Barb, J.2    Jiang, X.3    Wendland, J.R.4    Choi, K.H.5    Sen, S.K.6
  • 77
    • 34548297658 scopus 로고    scopus 로고
    • Expression profiling in monozygotic twins discordant for bipolar disorder reveals dysregulation of the WNT signalling pathway
    • Matigian N, Windus L, Smith H, Filippich C, Pantelis C, McGrath J et al. Expression profiling in monozygotic twins discordant for bipolar disorder reveals dysregulation of the WNT signalling pathway. Mol Psychiatry 2007; 12: 815-825.
    • (2007) Mol Psychiatry , vol.12 , pp. 815-825
    • Matigian, N.1    Windus, L.2    Smith, H.3    Filippich, C.4    Pantelis, C.5    McGrath, J.6
  • 79
    • 45449091369 scopus 로고    scopus 로고
    • Shared gene expression alterations in schizophrenia and bipolar disorder
    • Shao L, Vawter MP. Shared gene expression alterations in schizophrenia and bipolar disorder. Biol Psychiatry 2008; 64: 89-97.
    • (2008) Biol Psychiatry , vol.64 , pp. 89-97
    • Shao, L.1    Vawter, M.P.2
  • 80
    • 84929133091 scopus 로고    scopus 로고
    • Transcriptome sequencing and genome-wide association analyses reveal lysosomal function and actin cytoskeleton remodeling in schizophrenia and bipolar disorder
    • Zhao Z, Xu J, Chen J, Kim S, Reimers M, Bacanu SA et al. Transcriptome sequencing and genome-wide association analyses reveal lysosomal function and actin cytoskeleton remodeling in schizophrenia and bipolar disorder. Mol Psychiatry 2015; 20: 563-572.
    • (2015) Mol Psychiatry , vol.20 , pp. 563-572
    • Zhao, Z.1    Xu, J.2    Chen, J.3    Kim, S.4    Reimers, M.5    Bacanu, S.A.6
  • 81
    • 33749130645 scopus 로고    scopus 로고
    • Gene expression analysis of bipolar disorder reveals downregulation of the ubiquitin cycle and alterations in synaptic genes
    • Ryan MM, Lockstone HE, Huffaker SJ, Wayland MT, Webster MJ, Bahn S. Gene expression analysis of bipolar disorder reveals downregulation of the ubiquitin cycle and alterations in synaptic genes. Mol Psychiatry 2006; 11: 965-978.
    • (2006) Mol Psychiatry , vol.11 , pp. 965-978
    • Ryan, M.M.1    Lockstone, H.E.2    Huffaker, S.J.3    Wayland, M.T.4    Webster, M.J.5    Bahn, S.6
  • 82
    • 84946114235 scopus 로고    scopus 로고
    • Transcriptome sequencing of the anterior cingulate in bipolar disorder: Dysregulation of G protein-coupled receptors
    • Cruceanu C, Tan PP, Rogic S, Lopez JP, Torres-Platas SG, Gigek CO et al. Transcriptome sequencing of the anterior cingulate in bipolar disorder: dysregulation of G protein-coupled receptors. Am J Psychiatry 2015; 172: 1131-1140.
    • (2015) Am J Psychiatry , vol.172 , pp. 1131-1140
    • Cruceanu, C.1    Tan, P.P.2    Rogic, S.3    Lopez, J.P.4    Torres-Platas, S.G.5    Gigek, C.O.6
  • 83
    • 84937820134 scopus 로고    scopus 로고
    • Microarray analysis of the major depressive disorder mRNA profile data
    • Gao L, Gao Y, Xu E, Xie J. Microarray analysis of the major depressive disorder mRNA profile data. Psychiatry Investig 2015; 12: 388-396.
    • (2015) Psychiatry Investig , vol.12 , pp. 388-396
    • Gao, L.1    Gao, Y.2    Xu, E.3    Xie, J.4
  • 85
  • 86
    • 79957873236 scopus 로고    scopus 로고
    • Transcription and pathway analysis of the superior temporal cortex and anterior prefrontal cortex in schizophrenia
    • Barnes MR, Huxley-Jones J, Maycox PR, Lennon M, Thornber A, Kelly F et al. Transcription and pathway analysis of the superior temporal cortex and anterior prefrontal cortex in schizophrenia. J Neurosci Res 2011; 89: 1218-1227.
    • (2011) J Neurosci Res , vol.89 , pp. 1218-1227
    • Barnes, M.R.1    Huxley-Jones, J.2    Maycox, P.R.3    Lennon, M.4    Thornber, A.5    Kelly, F.6
  • 87
    • 70450223147 scopus 로고    scopus 로고
    • Analysis of gene expression in two large schizophrenia cohorts identifies multiple changes associated with nerve terminal function
    • Maycox PR, Kelly F, Taylor A, Bates S, Reid J, Logendra R et al. Analysis of gene expression in two large schizophrenia cohorts identifies multiple changes associated with nerve terminal function. Mol Psychiatry 2009; 14: 1083-1094.
    • (2009) Mol Psychiatry , vol.14 , pp. 1083-1094
    • Maycox, P.R.1    Kelly, F.2    Taylor, A.3    Bates, S.4    Reid, J.5    Logendra, R.6
  • 88
    • 84873056640 scopus 로고    scopus 로고
    • Genome-wide expression profiling of schizophrenia using a large combined cohort
    • Mistry M, Gillis J, Pavlidis P. Genome-wide expression profiling of schizophrenia using a large combined cohort. Mol Psychiatry 2013; 18: 215-225.
    • (2013) Mol Psychiatry , vol.18 , pp. 215-225
    • Mistry, M.1    Gillis, J.2    Pavlidis, P.3
  • 89
    • 84873055619 scopus 로고    scopus 로고
    • Increased inflammatory markers identified in the dorsolateral prefrontal cortex of individuals with schizophrenia
    • Fillman SG, Cloonan N, Catts VS, Miller LC, Wong J, McCrossin T et al. Increased inflammatory markers identified in the dorsolateral prefrontal cortex of individuals with schizophrenia. Mol Psychiatry 2013; 18: 206-214.
    • (2013) Mol Psychiatry , vol.18 , pp. 206-214
    • Fillman, S.G.1    Cloonan, N.2    Catts, V.S.3    Miller, L.C.4    Wong, J.5    McCrossin, T.6
  • 90
    • 84884672482 scopus 로고    scopus 로고
    • Inflammatory and immune response genes have significantly altered expression in schizophrenia
    • Sainz J, Mata I, Barrera J, Perez-Iglesias R, Varela I, Arranz MJ et al. Inflammatory and immune response genes have significantly altered expression in schizophrenia. Mol Psychiatry 2013; 18: 1056-1057.
    • (2013) Mol Psychiatry , vol.18 , pp. 1056-1057
    • Sainz, J.1    Mata, I.2    Barrera, J.3    Perez-Iglesias, R.4    Varela, I.5    Arranz, M.J.6
  • 92
    • 77953545111 scopus 로고    scopus 로고
    • Gene expression studies in major depression
    • Mehta D, Menke A, Binder EB. Gene expression studies in major depression. Curr Psychiatry Rep 2010; 12: 135-144.
    • (2010) Curr Psychiatry Rep , vol.12 , pp. 135-144
    • Mehta, D.1    Menke, A.2    Binder, E.B.3
  • 93
    • 84884212298 scopus 로고    scopus 로고
    • Enrichment of cis-regulatory gene expression SNPs and methylation quantitative trait loci among bipolar disorder susceptibility variants
    • Gamazon ER, Badner JA, Cheng L, Zhang C, Zhang D, Cox NJ et al. Enrichment of cis-regulatory gene expression SNPs and methylation quantitative trait loci among bipolar disorder susceptibility variants. Mol Psychiatry 2013; 18: 340-346.
    • (2013) Mol Psychiatry , vol.18 , pp. 340-346
    • Gamazon, E.R.1    Badner, J.A.2    Cheng, L.3    Zhang, C.4    Zhang, D.5    Cox, N.J.6
  • 94
    • 84856228535 scopus 로고    scopus 로고
    • Schizophrenia susceptibility alleles are enriched for alleles that affect gene expression in adult human brain
    • Richards AL, Jones L, Moskvina V, Kirov G, Gejman PV, Levinson DF et al. Schizophrenia susceptibility alleles are enriched for alleles that affect gene expression in adult human brain. Mol Psychiatry 2012; 17: 193-201.
    • (2012) Mol Psychiatry , vol.17 , pp. 193-201
    • Richards, A.L.1    Jones, L.2    Moskvina, V.3    Kirov, G.4    Gejman, P.V.5    Levinson, D.F.6
  • 96
    • 79955550445 scopus 로고    scopus 로고
    • A user's guide to the encyclopedia of DNA elements (ENCODE)
    • Encode Project Consortium
    • Encode Project Consortium. A user's guide to the encyclopedia of DNA elements (ENCODE). PLoS Biol 2011; 9: e1001046.
    • (2011) PLoS Biol , vol.9 , pp. e1001046
  • 97
    • 84923362619 scopus 로고    scopus 로고
    • Integrative analysis of 111 reference human epigenomes
    • Roadmap Epigenomics Consortium
    • Roadmap Epigenomics Consortium, Kundaje A, Meuleman W, Ernst J, Bilenky M, Yen A et al. Integrative analysis of 111 reference human epigenomes. Nature 2015; 518: 317-330.
    • (2015) Nature , vol.518 , pp. 317-330
    • Kundaje, A.1    Meuleman, W.2    Ernst, J.3    Bilenky, M.4    Yen, A.5
  • 99
    • 84858779229 scopus 로고    scopus 로고
    • HaploReg: A resource for exploring chromatin states, conservation, and regulatory motif alterations within sets of genetically linked variants
    • Ward LD, Kellis M. HaploReg: a resource for exploring chromatin states, conservation, and regulatory motif alterations within sets of genetically linked variants. Nucleic Acids Res 2012; 40: D930-D934.
    • (2012) Nucleic Acids Res , vol.40 , pp. D930-D934
    • Ward, L.D.1    Kellis, M.2
  • 100
    • 84895510920 scopus 로고    scopus 로고
    • Functional annotation of noncoding sequence variants
    • Ritchie GR, Dunham I, Zeggini E, Flicek P. Functional annotation of noncoding sequence variants. Nat Methods 2014; 11: 294-296.
    • (2014) Nat Methods , vol.11 , pp. 294-296
    • Ritchie, G.R.1    Dunham, I.2    Zeggini, E.3    Flicek, P.4
  • 101
    • 84867562866 scopus 로고    scopus 로고
    • FunciSNP: An R/ bioconductor tool integrating functional non-coding data sets with genetic association studies to identify candidate regulatory SNPs
    • Coetzee SG, Rhie SK, Berman BP, Coetzee GA, Noushmehr H. FunciSNP: an R/ bioconductor tool integrating functional non-coding data sets with genetic association studies to identify candidate regulatory SNPs. Nucleic Acids Res 2012; 40: e139.
    • (2012) Nucleic Acids Res , vol.40 , pp. e139
    • Coetzee, S.G.1    Rhie, S.K.2    Berman, B.P.3    Coetzee, G.A.4    Noushmehr, H.5
  • 105
    • 76049095642 scopus 로고    scopus 로고
    • Mapping allele-specific DNA methylation: A new tool for maximizing information from GWAS
    • Tycko B. Mapping allele-specific DNA methylation: a new tool for maximizing information from GWAS. Am J Hum Genet 2010; 86: 109-112.
    • (2010) Am J Hum Genet , vol.86 , pp. 109-112
    • Tycko, B.1
  • 106
    • 77957911410 scopus 로고    scopus 로고
    • Allele-specific methylation in the human genome: Implications for genetic studies of complex disease
    • Meaburn EL, Schalkwyk LC, Mill J. Allele-specific methylation in the human genome: implications for genetic studies of complex disease. Epigenetics 2010; 5: 578-582.
    • (2010) Epigenetics , vol.5 , pp. 578-582
    • Meaburn, E.L.1    Schalkwyk, L.C.2    Mill, J.3
  • 107
    • 84953729873 scopus 로고    scopus 로고
    • Methylation QTLs in the developing brain and their enrichment in schizophrenia risk loci
    • Hannon E, Spiers H, Viana J, Pidsley R, Burrage J, Murphy TM et al. Methylation QTLs in the developing brain and their enrichment in schizophrenia risk loci. Nat Neurosci 2016; 19: 48-54.
    • (2016) Nat Neurosci , vol.19 , pp. 48-54
    • Hannon, E.1    Spiers, H.2    Viana, J.3    Pidsley, R.4    Burrage, J.5    Murphy, T.M.6
  • 108
    • 84953762043 scopus 로고    scopus 로고
    • Mapping DNA methylation across development, genotype and schizophrenia in the human frontal cortex
    • Jaffe AE, Gao Y, Deep-Soboslay A, Tao R, Hyde TM, Weinberger DR et al. Mapping DNA methylation across development, genotype and schizophrenia in the human frontal cortex. Nat Neurosci 2016; 19: 40-47.
    • (2016) Nat Neurosci , vol.19 , pp. 40-47
    • Jaffe, A.E.1    Gao, Y.2    Deep-Soboslay, A.3    Tao, R.4    Hyde, T.M.5    Weinberger, D.R.6
  • 109
    • 84963610123 scopus 로고    scopus 로고
    • Allele-skewed DNA modification in the brain: Relevance to a schizophrenia GWAS
    • Gagliano SA, Ptak C, Mak DY, Shamsi M, Oh G, Knight J et al. Allele-skewed DNA modification in the brain: relevance to a schizophrenia GWAS. Am J Hum Genet 2016; 98: 956-962.
    • (2016) Am J Hum Genet , vol.98 , pp. 956-962
    • Gagliano, S.A.1    Ptak, C.2    Mak, D.Y.3    Shamsi, M.4    Oh, G.5    Knight, J.6
  • 111
    • 38649099445 scopus 로고    scopus 로고
    • Highresolution mapping and characterization of open chromatin across the genome
    • Boyle AP, Davis S, Shulha HP, Meltzer P, Margulies EH, Weng Z et al. Highresolution mapping and characterization of open chromatin across the genome. Cell 2008; 132: 311-322.
    • (2008) Cell , vol.132 , pp. 311-322
    • Boyle, A.P.1    Davis, S.2    Shulha, H.P.3    Meltzer, P.4    Margulies, E.H.5    Weng, Z.6
  • 112
    • 0035845482 scopus 로고    scopus 로고
    • Investigating stem cells in human colon by using methylation patterns
    • Yatabe Y, Tavare S, Shibata D. Investigating stem cells in human colon by using methylation patterns. Proc Natl Acad Sci USA 2001; 98: 10839-10844.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 10839-10844
    • Yatabe, Y.1    Tavare, S.2    Shibata, D.3
  • 114
    • 70349326007 scopus 로고    scopus 로고
    • Genomic interactions: Chromatin loops and gene meeting points in transcriptional regulation
    • Sexton T, Bantignies F, Cavalli G. Genomic interactions: chromatin loops and gene meeting points in transcriptional regulation. Semin Cell Dev Biol 2009; 20: 849-855.
    • (2009) Semin Cell Dev Biol , vol.20 , pp. 849-855
    • Sexton, T.1    Bantignies, F.2    Cavalli, G.3
  • 116
    • 84875933011 scopus 로고    scopus 로고
    • Functional variants at the 11q13 risk locus for breast cancer regulate cyclin D1 expression through long-range enhancers
    • French JD, Ghoussaini M, Edwards SL, Meyer KB, Michailidou K, Ahmed S et al. Functional variants at the 11q13 risk locus for breast cancer regulate cyclin D1 expression through long-range enhancers. Am J Hum Genet 2013; 92: 489-503.
    • (2013) Am J Hum Genet , vol.92 , pp. 489-503
    • French, J.D.1    Ghoussaini, M.2    Edwards, S.L.3    Meyer, K.B.4    Michailidou, K.5    Ahmed, S.6
  • 117
    • 84889578835 scopus 로고    scopus 로고
    • A polymorphism in IRF4 affects human pigmentation through a tyrosinasedependent MITF/TFAP2A pathway
    • Praetorius C, Grill C, Stacey SN, Metcalf AM, Gorkin DU, Robinson KC et al. A polymorphism in IRF4 affects human pigmentation through a tyrosinasedependent MITF/TFAP2A pathway. Cell 2013; 155: 1022-1033.
    • (2013) Cell , vol.155 , pp. 1022-1033
    • Praetorius, C.1    Grill, C.2    Stacey, S.N.3    Metcalf, A.M.4    Gorkin, D.U.5    Robinson, K.C.6
  • 119
    • 84919674518 scopus 로고    scopus 로고
    • A rare functional noncoding variant at the GWAS-implicated MIR137/MIR2682 locus might confer risk to schizophrenia and bipolar disorder
    • Duan J, Shi J, Fiorentino A, Leites C, Chen X, Moy W et al. A rare functional noncoding variant at the GWAS-implicated MIR137/MIR2682 locus might confer risk to schizophrenia and bipolar disorder. Am J Hum Genet 2014; 95: 744-753.
    • (2014) Am J Hum Genet , vol.95 , pp. 744-753
    • Duan, J.1    Shi, J.2    Fiorentino, A.3    Leites, C.4    Chen, X.5    Moy, W.6
  • 121
    • 84905023068 scopus 로고    scopus 로고
    • A rare mutation of CACNA1C in a patient with bipolar disorder, and decreased gene expression associated with a bipolar-associated common SNP of CACNA1C in brain
    • Gershon ES, Grennan K, Busnello J, Badner JA, Ovsiew F, Memon S et al. A rare mutation of CACNA1C in a patient with bipolar disorder, and decreased gene expression associated with a bipolar-associated common SNP of CACNA1C in brain. Mol Psychiatry 2014; 19: 890-894.
    • (2014) Mol Psychiatry , vol.19 , pp. 890-894
    • Gershon, E.S.1    Grennan, K.2    Busnello, J.3    Badner, J.A.4    Ovsiew, F.5    Memon, S.6
  • 123
    • 84938523327 scopus 로고    scopus 로고
    • Functional implications of a psychiatric risk variant within CACNA1C in induced human neurons
    • Yoshimizu T, Pan JQ, Mungenast AE, Madison JM, Su S, Ketterman J et al. Functional implications of a psychiatric risk variant within CACNA1C in induced human neurons. Mol Psychiatry 2015; 20: 162-169.
    • (2015) Mol Psychiatry , vol.20 , pp. 162-169
    • Yoshimizu, T.1    Pan, J.Q.2    Mungenast, A.E.3    Madison, J.M.4    Su, S.5    Ketterman, J.6
  • 124
    • 84975318556 scopus 로고    scopus 로고
    • Functional characterization of schizophrenia-associated variation in CACNA1C
    • Eckart N, Song Q, Yang R, Wang R, Zhu H, McCallion AS et al. Functional characterization of schizophrenia-associated variation in CACNA1C. PLoS One 2016; 11: e0157086.
    • (2016) PLoS One , vol.11 , pp. e0157086
    • Eckart, N.1    Song, Q.2    Yang, R.3    Wang, R.4    Zhu, H.5    McCallion, A.S.6
  • 125
    • 33749400168 scopus 로고    scopus 로고
    • Chromosome Conformation Capture Carbon Copy (5C): A massively parallel solution for mapping interactions between genomic elements
    • Dostie J, Richmond TA, Arnaout RA, Selzer RR, Lee WL, Honan TA et al. Chromosome Conformation Capture Carbon Copy (5C): a massively parallel solution for mapping interactions between genomic elements. Genome Res 2006; 16: 1299-1309.
    • (2006) Genome Res , vol.16 , pp. 1299-1309
    • Dostie, J.1    Richmond, T.A.2    Arnaout, R.A.3    Selzer, R.R.4    Lee, W.L.5    Honan, T.A.6
  • 127
    • 70449103609 scopus 로고    scopus 로고
    • An oestrogen-receptor-alpha-bound human chromatin interactome
    • Fullwood MJ, Liu MH, Pan YF, Liu J, Xu H, Mohamed YB et al. An oestrogen-receptor-alpha-bound human chromatin interactome. Nature 2009; 462: 58-64.
    • (2009) Nature , vol.462 , pp. 58-64
    • Fullwood, M.J.1    Liu, M.H.2    Pan, Y.F.3    Liu, J.4    Xu, H.5    Mohamed, Y.B.6
  • 128
    • 84862908850 scopus 로고    scopus 로고
    • Extensive promoter-centered chromatin interactions provide a topological basis for transcription regulation
    • Li G, Ruan X, Auerbach RK, Sandhu KS, Zheng M, Wang P et al. Extensive promoter-centered chromatin interactions provide a topological basis for transcription regulation. Cell 2012; 148: 84-98.
    • (2012) Cell , vol.148 , pp. 84-98
    • Li, G.1    Ruan, X.2    Auerbach, R.K.3    Sandhu, K.S.4    Zheng, M.5    Wang, P.6
  • 129
    • 84857781464 scopus 로고    scopus 로고
    • Characterization of genome-wide enhancer-promoter interactions reveals co-expression of interacting genes and modes of higher order chromatin organization
    • Chepelev I, Wei G, Wangsa D, Tang Q, Zhao K. Characterization of genome-wide enhancer-promoter interactions reveals co-expression of interacting genes and modes of higher order chromatin organization. Cell Res 2012; 22: 490-503.
    • (2012) Cell Res , vol.22 , pp. 490-503
    • Chepelev, I.1    Wei, G.2    Wangsa, D.3    Tang, Q.4    Zhao, K.5
  • 130
    • 79959699992 scopus 로고    scopus 로고
    • CTCF-mediated functional chromatin interactome in pluripotent cells
    • Handoko L, Xu H, Li G, Ngan CY, Chew E, Schnapp M et al. CTCF-mediated functional chromatin interactome in pluripotent cells. Nat Genet 2011; 43: 630-638.
    • (2011) Nat Genet , vol.43 , pp. 630-638
    • Handoko, L.1    Xu, H.2    Li, G.3    Ngan, C.Y.4    Chew, E.5    Schnapp, M.6
  • 131
    • 84893788391 scopus 로고    scopus 로고
    • Aberrant TAL1 activation is mediated by an interchromosomal interaction in human T-cell acute lymphoblastic leukemia
    • Patel B, Kang Y, Cui K, Litt M, Riberio MS, Deng C et al. Aberrant TAL1 activation is mediated by an interchromosomal interaction in human T-cell acute lymphoblastic leukemia. Leukemia 2014; 28: 349-361.
    • (2014) Leukemia , vol.28 , pp. 349-361
    • Patel, B.1    Kang, Y.2    Cui, K.3    Litt, M.4    Riberio, M.S.5    Deng, C.6
  • 132
    • 79951473520 scopus 로고    scopus 로고
    • 9p21 DNA variants associated with coronary artery disease impair interferon-gamma signalling response
    • Harismendy O, Notani D, Song X, Rahim NG, Tanasa B, Heintzman N et al. 9p21 DNA variants associated with coronary artery disease impair interferon-gamma signalling response. Nature 2011; 470: 264-268.
    • (2011) Nature , vol.470 , pp. 264-268
    • Harismendy, O.1    Notani, D.2    Song, X.3    Rahim, N.G.4    Tanasa, B.5    Heintzman, N.6
  • 133
    • 84878092919 scopus 로고    scopus 로고
    • Comprehensive functional annotation of seventy-one breast cancer risk Loci
    • Rhie SK, Coetzee SG, Noushmehr H, Yan C, Kim JM, Haiman CA et al. Comprehensive functional annotation of seventy-one breast cancer risk Loci. PLoS One 2013; 8: e63925.
    • (2013) PLoS One , vol.8 , pp. e63925
    • Rhie, S.K.1    Coetzee, S.G.2    Noushmehr, H.3    Yan, C.4    Kim, J.M.5    Haiman, C.A.6
  • 135
    • 84863115845 scopus 로고    scopus 로고
    • Allelic differences between Han Chinese and Europeans for functional variants in ZNF804A and their association with schizophrenia
    • Li M, Luo XJ, Xiao X, Shi L, Liu XY, Yin LD et al. Allelic differences between Han Chinese and Europeans for functional variants in ZNF804A and their association with schizophrenia. Am J Psychiatry 2011; 168: 1318-1325.
    • (2011) Am J Psychiatry , vol.168 , pp. 1318-1325
    • Li, M.1    Luo, X.J.2    Xiao, X.3    Shi, L.4    Liu, X.Y.5    Yin, L.D.6
  • 136
    • 79960845464 scopus 로고    scopus 로고
    • Allelic differences in nuclear protein binding at a genome-wide significant risk variant for schizophrenia in ZNF804A
    • Hill MJ, Bray NJ. Allelic differences in nuclear protein binding at a genome-wide significant risk variant for schizophrenia in ZNF804A. Mol Psychiatry 2011; 16: 787-789.
    • (2011) Mol Psychiatry , vol.16 , pp. 787-789
    • Hill, M.J.1    Bray, N.J.2
  • 137
    • 84878630996 scopus 로고    scopus 로고
    • Genetic association, mutation screening, and functional analysis of a Kozak sequence variant in the metabotropic glutamate receptor 3 gene in bipolar disorder
    • Kandaswamy R, McQuillin A, Sharp SI, Fiorentino A, Anjorin A, Blizard RA et al. Genetic association, mutation screening, and functional analysis of a Kozak sequence variant in the metabotropic glutamate receptor 3 gene in bipolar disorder. JAMA Psychiatry 2013; 70: 591-598.
    • (2013) JAMA Psychiatry , vol.70 , pp. 591-598
    • Kandaswamy, R.1    McQuillin, A.2    Sharp, S.I.3    Fiorentino, A.4    Anjorin, A.5    Blizard, R.A.6
  • 138
    • 84866890450 scopus 로고    scopus 로고
    • Proteome-wide analysis of disease-associated SNPs that show allele-specific transcription factor binding
    • Butter F, Davison L, Viturawong T, Scheibe M, Vermeulen M, Todd JA et al. Proteome-wide analysis of disease-associated SNPs that show allele-specific transcription factor binding. PLoS Genet 2012; 8: e1002982.
    • (2012) PLoS Genet , vol.8 , pp. e1002982
    • Butter, F.1    Davison, L.2    Viturawong, T.3    Scheibe, M.4    Vermeulen, M.5    Todd, J.A.6
  • 139
    • 84859853681 scopus 로고    scopus 로고
    • Minigenes to confirm exon skipping mutations
    • Desviat LR, Perez B, Ugarte M. Minigenes to confirm exon skipping mutations. Methods Mol Biol 2012; 867: 37-47.
    • (2012) Methods Mol Biol , vol.867 , pp. 37-47
    • Desviat, L.R.1    Perez, B.2    Ugarte, M.3
  • 140
    • 27944439248 scopus 로고    scopus 로고
    • Use of minigene systems to dissect alternative splicing elements
    • Cooper TA. Use of minigene systems to dissect alternative splicing elements. Methods 2005; 37: 331-340.
    • (2005) Methods , vol.37 , pp. 331-340
    • Cooper, T.A.1
  • 141
    • 84940934684 scopus 로고    scopus 로고
    • A splicing-regulatory polymorphism in DRD2 disrupts ZRANB2 binding, impairs cognitive functioning and increases risk for schizophrenia in six Han Chinese samples
    • Cohen OS, Weickert TW, Hess JL, Paish LM, McCoy SY, Rothmond DA et al. A splicing-regulatory polymorphism in DRD2 disrupts ZRANB2 binding, impairs cognitive functioning and increases risk for schizophrenia in six Han Chinese samples. Mol Psychiatry 2015; 21: 975-982.
    • (2015) Mol Psychiatry , vol.21 , pp. 975-982
    • Cohen, O.S.1    Weickert, T.W.2    Hess, J.L.3    Paish, L.M.4    McCoy, S.Y.5    Rothmond, D.A.6
  • 142
    • 84886080706 scopus 로고    scopus 로고
    • Functional analysis of deep intronic SNP rs13438494 in intron 24 of PCLO gene
    • Seo S, Takayama K, Uno K, Ohi K, Hashimoto R, Nishizawa D et al. Functional analysis of deep intronic SNP rs13438494 in intron 24 of PCLO gene. PLoS One 2013; 8: e76960.
    • (2013) PLoS One , vol.8 , pp. e76960
    • Seo, S.1    Takayama, K.2    Uno, K.3    Ohi, K.4    Hashimoto, R.5    Nishizawa, D.6
  • 143
    • 84957609388 scopus 로고    scopus 로고
    • KCNH2-3.1 expression impairs cognition and alters neuronal function in a model of molecular pathology associated with schizophrenia
    • Carr GV, Chen J, Yang F, Ren M, Yuan P, Tian Q et al. KCNH2-3.1 expression impairs cognition and alters neuronal function in a model of molecular pathology associated with schizophrenia. Mol Psychiatry 2016; 21: 1517-1526.
    • (2016) Mol Psychiatry , vol.21 , pp. 1517-1526
    • Carr, G.V.1    Chen, J.2    Yang, F.3    Ren, M.4    Yuan, P.5    Tian, Q.6
  • 144
    • 84957536784 scopus 로고    scopus 로고
    • Autism-like behaviours and germline transmission in transgenic monkeys overexpressing MeCP2
    • Liu Z, Li X, Zhang JT, Cai YJ, Cheng TL, Cheng C et al. Autism-like behaviours and germline transmission in transgenic monkeys overexpressing MeCP2. Nature 2016; 530: 98-102.
    • (2016) Nature , vol.530 , pp. 98-102
    • Liu, Z.1    Li, X.2    Zhang, J.T.3    Cai, Y.J.4    Cheng, T.L.5    Cheng, C.6
  • 146
    • 84940978728 scopus 로고    scopus 로고
    • Human neuropsychiatric disease modeling using conditional deletion reveals synaptic transmission defects caused by heterozygous mutations in NRXN1
    • Pak C, Danko T, Zhang Y, Aoto J, Anderson G, Maxeiner S et al. Human neuropsychiatric disease modeling using conditional deletion reveals synaptic transmission defects caused by heterozygous mutations in NRXN1. Cell Stem Cell 2015; 17: 316-328.
    • (2015) Cell Stem Cell , vol.17 , pp. 316-328
    • Pak, C.1    Danko, T.2    Zhang, Y.3    Aoto, J.4    Anderson, G.5    Maxeiner, S.6
  • 148
    • 2942614921 scopus 로고    scopus 로고
    • Catechol-Omethyltransferase inhibition improves set-shifting performance and elevates stimulated dopamine release in the rat prefrontal cortex
    • Tunbridge EM, Bannerman DM, Sharp T, Harrison PJ. Catechol-Omethyltransferase inhibition improves set-shifting performance and elevates stimulated dopamine release in the rat prefrontal cortex. J Neurosci 2004; 24: 5331-5335.
    • (2004) J Neurosci , vol.24 , pp. 5331-5335
    • Tunbridge, E.M.1    Bannerman, D.M.2    Sharp, T.3    Harrison, P.J.4
  • 149
    • 6344265879 scopus 로고    scopus 로고
    • Functional analysis of genetic variation in catechol-O-methyltransferase (COMT): Effects on mRNA, protein, and enzyme activity in postmortem human brain
    • Chen J, Lipska BK, Halim N, Ma QD, Matsumoto M, Melhem S et al. Functional analysis of genetic variation in catechol-O-methyltransferase (COMT): effects on mRNA, protein, and enzyme activity in postmortem human brain. Am J Hum Genet 2004; 75: 807-821.
    • (2004) Am J Hum Genet , vol.75 , pp. 807-821
    • Chen, J.1    Lipska, B.K.2    Halim, N.3    Ma, Q.D.4    Matsumoto, M.5    Melhem, S.6
  • 151
    • 0028918413 scopus 로고
    • Kinetics of human soluble and membrane-bound catechol O-methyltransferase: A revised mechanism and description of the thermolabile variant of the enzyme
    • Lotta T, Vidgren J, Tilgmann C, Ulmanen I, Melen K, Julkunen I et al. Kinetics of human soluble and membrane-bound catechol O-methyltransferase: a revised mechanism and description of the thermolabile variant of the enzyme. Biochemistry 1995; 34: 4202-4210.
    • (1995) Biochemistry , vol.34 , pp. 4202-4210
    • Lotta, T.1    Vidgren, J.2    Tilgmann, C.3    Ulmanen, I.4    Melen, K.5    Julkunen, I.6
  • 152
    • 0032777995 scopus 로고    scopus 로고
    • Global variation in the frequencies of functionally different catechol-O-methyltransferase alleles
    • Palmatier MA, Kang AM, Kidd KK. Global variation in the frequencies of functionally different catechol-O-methyltransferase alleles. Biol Psychiatry 1999; 46: 557-567.
    • (1999) Biol Psychiatry , vol.46 , pp. 557-567
    • Palmatier, M.A.1    Kang, A.M.2    Kidd, K.K.3
  • 153
    • 84981172870 scopus 로고    scopus 로고
    • Genotypedependent effects of COMT inhibition on cognitive function in a highly-specific, novel mouse model of altered COMT activity
    • Barkus C, Korn C, Stumpenhorst K, Laatikainen L, Ballard D, Lee S et al. Genotypedependent effects of COMT inhibition on cognitive function in a highly-specific, novel mouse model of altered COMT activity. Neuropsychopharmacology 2016; 41: 3060-3069.
    • (2016) Neuropsychopharmacology , vol.41 , pp. 3060-3069
    • Barkus, C.1    Korn, C.2    Stumpenhorst, K.3    Laatikainen, L.4    Ballard, D.5    Lee, S.6
  • 155
    • 84891808382 scopus 로고    scopus 로고
    • JASPAR 2014: An extensively expanded and updated open-access database of transcription factor binding profiles
    • Mathelier A, Zhao X, Zhang AW, Parcy F, Worsley-Hunt R, Arenillas DJ et al. JASPAR 2014: an extensively expanded and updated open-access database of transcription factor binding profiles. Nucleic Acids Res 2014; 42: D142-D147.
    • (2014) Nucleic Acids Res , vol.42 , pp. D142-D147
    • Mathelier, A.1    Zhao, X.2    Zhang, A.W.3    Parcy, F.4    Worsley-Hunt, R.5    Arenillas, D.J.6
  • 156
    • 13444270902 scopus 로고    scopus 로고
    • The MAPPER database: A multi-genome catalog of putative transcription factor binding sites
    • Marinescu VD, Kohane IS, Riva A. The MAPPER database: a multi-genome catalog of putative transcription factor binding sites. Nucleic Acids Res 2005; 33: D91-D97.
    • (2005) Nucleic Acids Res , vol.33 , pp. D91-D97
    • Marinescu, V.D.1    Kohane, I.S.2    Riva, A.3
  • 157
    • 84883583576 scopus 로고    scopus 로고
    • GWAS3D: Detecting human regulatory variants by integrative analysis of genome-wide associations, chromosome interactions and histone modifications
    • Li MJ, Wang LY, Xia Z, Sham PC, Wang J. GWAS3D: Detecting human regulatory variants by integrative analysis of genome-wide associations, chromosome interactions and histone modifications. Nucleic Acids Res 2013; 41: W150-W158.
    • (2013) Nucleic Acids Res , vol.41 , pp. W150-W158
    • Li, M.J.1    Wang, L.Y.2    Xia, Z.3    Sham, P.C.4    Wang, J.5
  • 158
    • 84958257565 scopus 로고    scopus 로고
    • Predicting effects of noncoding variants with deep learning-based sequence model
    • Zhou J, Troyanskaya OG. Predicting effects of noncoding variants with deep learning-based sequence model. Nat Methods 2015; 12: 931-934.
    • (2015) Nat Methods , vol.12 , pp. 931-934
    • Zhou, J.1    Troyanskaya, O.G.2
  • 159
    • 80052022462 scopus 로고    scopus 로고
    • Cistrome: An integrative platform for transcriptional regulation studies
    • Liu T, Ortiz JA, Taing L, Meyer CA, Lee B, Zhang Y et al. Cistrome: an integrative platform for transcriptional regulation studies. Genome Biol 2011; 12: R83.
    • (2011) Genome Biol , vol.12 , pp. R83
    • Liu, T.1    Ortiz, J.A.2    Taing, L.3    Meyer, C.A.4    Lee, B.5    Zhang, Y.6
  • 161
    • 0037252736 scopus 로고    scopus 로고
    • An improved version of the DNA Methylation database (MethDB)
    • Amoreira C, Hindermann W, Grunau C. An improved version of the DNA Methylation database (MethDB). Nucleic Acids Res 2003; 31: 75-77.
    • (2003) Nucleic Acids Res , vol.31 , pp. 75-77
    • Amoreira, C.1    Hindermann, W.2    Grunau, C.3
  • 163
    • 84857062545 scopus 로고    scopus 로고
    • DNA methylation signatures in development and aging of the human prefrontal cortex
    • Numata S, Ye T, Hyde TM, Guitart-Navarro X, Tao R, Wininger M et al. DNA methylation signatures in development and aging of the human prefrontal cortex. Am J Hum Genet 2012; 90: 260-272.
    • (2012) Am J Hum Genet , vol.90 , pp. 260-272
    • Numata, S.1    Ye, T.2    Hyde, T.M.3    Guitart-Navarro, X.4    Tao, R.5    Wininger, M.6
  • 164
    • 84857707318 scopus 로고    scopus 로고
    • ChromHMM: Automating chromatin-state discovery and characterization
    • Ernst J, Kellis M. ChromHMM: automating chromatin-state discovery and characterization. Nat Methods 2012; 9: 215-216.
    • (2012) Nat Methods , vol.9 , pp. 215-216
    • Ernst, J.1    Kellis, M.2
  • 165
    • 77950404192 scopus 로고    scopus 로고
    • Quantifying the effect of sequence variation on regulatory interactions
    • Manke T, Heinig M, Vingron M. Quantifying the effect of sequence variation on regulatory interactions. Hum Mutat 2010; 31: 477-483.
    • (2010) Hum Mutat , vol.31 , pp. 477-483
    • Manke, T.1    Heinig, M.2    Vingron, M.3
  • 167
    • 70349873824 scopus 로고    scopus 로고
    • Comprehensive mapping of long-range interactions reveals folding principles of the human genome
    • Lieberman-Aiden E, van Berkum NL, Williams L, Imakaev M, Ragoczy T, Telling A et al. Comprehensive mapping of long-range interactions reveals folding principles of the human genome. Science 2009; 326: 289-293.
    • (2009) Science , vol.326 , pp. 289-293
    • Lieberman-Aiden, E.1    Van Berkum, N.L.2    Williams, L.3    Imakaev, M.4    Ragoczy, T.5    Telling, A.6
  • 168
    • 84970965504 scopus 로고    scopus 로고
    • CCSI: A database providing chromatin-chromatin spatial interaction information
    • Xie X, Ma W, Songyang Z, Luo Z, Huang J, Dai Z et al. CCSI: a database providing chromatin-chromatin spatial interaction information. Database (Oxford) 2016; 2016: bav124.
    • (2016) Database (Oxford) , vol.2016 , pp. bav124
    • Xie, X.1    Ma, W.2    Songyang, Z.3    Luo, Z.4    Huang, J.5    Dai, Z.6
  • 170
    • 11844278458 scopus 로고    scopus 로고
    • Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets
    • Lewis BP, Burge CB, Bartel DP. Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets. Cell 2005; 120: 15-20.
    • (2005) Cell , vol.120 , pp. 15-20
    • Lewis, B.P.1    Burge, C.B.2    Bartel, D.P.3
  • 171
    • 78049420577 scopus 로고    scopus 로고
    • MicroSNiPer: A web tool for prediction of SNP effects on putative microRNA targets
    • Barenboim M, Zoltick BJ, Guo Y, Weinberger DR. MicroSNiPer: a web tool for prediction of SNP effects on putative microRNA targets. Hum Mutat 2010; 31: 1223-1232.
    • (2010) Hum Mutat , vol.31 , pp. 1223-1232
    • Barenboim, M.1    Zoltick, B.J.2    Guo, Y.3    Weinberger, D.R.4


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