De Novo Synonymous Mutations in Regulatory Elements Contribute to the Genetic Etiology of Autism and Schizophrenia

Neuron

Volumn 89, Issue 5, 2016, Pages 940-947

  Takata, Atsushi ^a,c   Ionita Laza, Iuliana ^a   Gogos, Joseph A ^a   Xu, Bin ^a   Karayiorgou, Maria ^a,b  

^a NewYork Presbyterian Hospital   (United States)

^b NEW YORK STATE PSYCHIATRIC INSTITUTE   (United States)

^c RIKEN BRAIN SCIENCE INSTITUTE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

DEOXYRIBONUCLEASE I; MICRORNA; TRANSCRIPTION FACTOR; HISTONE LYSINE METHYLTRANSFERASE; NERVE PROTEIN; RAB PROTEIN; SETD1A PROTEIN, HUMAN;

ARTICLE; AUTISM; CHROMATIN; CODON; DEOXYRIBONUCLEASE I HYPERSENSITIVITY SITE; EXON; FRONTAL CORTEX; GENE; GENE MUTATION; MUTATIONAL ANALYSIS; PRIORITY JOURNAL; PROTEIN BINDING; RAB2A GENE; RNA BINDING; RNA SPLICING; RNA STRUCTURE; SCHIZOPHRENIA; SETD1A GENE; SYNONYMOUS MUTATION; DNA SEQUENCE; EXOME; FACTUAL DATABASE; FEMALE; GENETIC ASSOCIATION STUDY; GENETIC PREDISPOSITION; GENETICS; HUMAN; MACHINE LEARNING; MALE; MUTATION; REGULATORY SEQUENCE; STATISTICS AND NUMERICAL DATA;

AUTISTIC DISORDER; DATABASES, FACTUAL; EXOME; FEMALE; GENETIC ASSOCIATION STUDIES; GENETIC PREDISPOSITION TO DISEASE; HISTONE-LYSINE N-METHYLTRANSFERASE; HUMANS; MACHINE LEARNING; MALE; MICRORNAS; MUTATION; NERVE TISSUE PROTEINS; RAB2 GTP-BINDING PROTEIN; REGULATORY ELEMENTS, TRANSCRIPTIONAL; SCHIZOPHRENIA; SEQUENCE ANALYSIS, DNA;

EID: 84960469255     PISSN: 08966273     EISSN: 10974199     Source Type: Journal    
DOI: 10.1016/j.neuron.2016.02.024     Document Type: Article

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