Trans-eqtls reveal that independent genetic variants associated with a complex phenotype converge on intermediate genes, with a major role for the hla

PLoS Genetics

Volumn 7, Issue 8, 2011, Pages

  Fehrmann, Rudolf S N ^a   Jansen, Ritsert C ^b   Veldink, Jan H ^c   Westra, Harm Jan ^a   Arends, Danny ^b   Bonder, Marc Jan ^a   Fu, Jingyuan ^a   Deelen, Patrick ^a   Groen, Harry J M ^a   Smolonska, Asia ^a   Weersma, Rinse K ^a   Hofstra, Robert M W ^a   Buurman, Wim A ^d   Rensen, Sander ^d   Wolfs, Marcel G M ^a   Platteel, Mathieu ^a   Zhernakova, Alexandra ^e   Elbers, Clara C ^f   Festen, Eleanora M ^a   Trynka, Gosia ^a   Hofker, Marten H ^a   Saris, Christiaan G J ^c   Ophoff, Roel A ^c,g,h   van den Berg, Leonard H ^c   van Heel, David A ⁱ   Wijmenga, Cisca ^a   Meerman, Gerard J ^a   Franke, Lude ^a,i   more..

^a UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

^b UNIVERSITY OF GRONINGEN   (Netherlands)

^c UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^d MAASTRICHT UNIVERSITY MEDICAL CENTER   (Netherlands)

^e LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^f UNIVERSITY OF PENNSYLVANIA   (United States)

^g UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^h UNIVERSITY OF CALIFORNIA   (United States)

ⁱ QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

COLONY STIMULATING FACTOR 1 RECEPTOR; COLONY STIMULATING FACTOR RECEPTOR; HLA ANTIBODY; UNCLASSIFIED DRUG; HLA ANTIGEN;

ACYLOXYACYL HYDROLASE GENE; ARTICLE; CONTROLLED STUDY; CONVERGENT EVOLUTION; F13A1 GENE; GENE; GENE EXPRESSION PROFILING; GENE IDENTIFICATION; GENE LOCATION; GENE PROBE; GENE REPLICATION; GENETIC ASSOCIATION; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; GENOME ANALYSIS; GNG11 GENE; GP9 GENE; HUMAN; INTRAABDOMINAL FAT; MUSCLE TISSUE; PHENOTYPE; PROTEIN FUNCTION; QUANTITATIVE TRAIT LOCUS MAPPING; SAMD14 GENE; SINGLE NUCLEOTIDE POLYMORPHISM; SUBCUTANEOUS FAT; T CELL RECEPTOR BETA VARIABLE 18 GENE; THROMBOCYTE VOLUME; TRANSGENE; ULCERATIVE COLITIS; VCL GENE; CHROMOSOME MAP; GENE EXPRESSION REGULATION; GENETICS; GENOTYPE; METABOLISM; MONOCYTE; QUANTITATIVE TRAIT LOCUS;

CHROMOSOME MAPPING; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENETIC VARIATION; GENOME-WIDE ASSOCIATION STUDY; GENOTYPE; HLA ANTIGENS; HUMANS; MONOCYTES; PHENOTYPE; POLYMORPHISM, SINGLE NUCLEOTIDE; QUANTITATIVE TRAIT LOCI;

EID: 80052322958     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1002197     Document Type: Article

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