Functional variants at the 11q13 risk locus for breast cancer regulate cyclin D1 expression through long-range enhancers

American Journal of Human Genetics

Volumn 92, Issue 4, 2013, Pages 489-503

  French, Juliet D ^a   Ghoussaini, Maya ^b   Edwards, Stacey L ^a   Meyer, Kerstin B ^c   Michailidou, Kyriaki ^b   Ahmed, Shahana ^b   Khan, Sofia ^d   Maranian, Mel J ^b   O'Reilly, Martin ^c   Hillman, Kristine M ^a   Betts, Joshua A ^a   Carroll, Thomas ^c   Bailey, Peter J ^a   Dicks, Ed ^b   Beesley, Jonathan ^e   Tyrer, Jonathan ^b   Maia, Ana Teresa ^c   Beck, Andrew ^f   Knoblauch, Nicholas W ^f   Chen, Constance ^g   Kraft, Peter ^g   Barnes, Daniel ^b   González Neira, Anna ^h   Alonso, M Rosario ^h   Herrero, Daniel ^h   Tessier, Daniel C ⁱ   Vincent, Daniel ⁱ   Bacot, Francois ⁱ   Luccarini, Craig ^b   Baynes, Caroline ^b   Conroy, Don ^b   Dennis, Joe ^b   Bolla, Manjeet K ^b   Wang, Qin ^b   Hopper, John L ^j   Southey, Melissa C ^j   Schmidt, Marjanka K ^k   Broeks, Annegien ^k   Verhoef, Senno ^k   Cornelissen, Sten ^k   Muir, Kenneth ^l   Lophatananon, Artitaya ^l   Stewart Brown, Sarah ^l   Siriwanarangsan, Pornthep ^m   Fasching, Peter A ^n,o   Loehberg, Christian R ^o   Ekici, Arif B ^p   Beckmann, Matthias W ^o   Peto, Julian ^q   Dos Santos Silva, Isabel ^q   Johnson, Nichola ^r   Aitken, Zoe ^q   Sawyer, Elinor J ^s   Tomlinson, Ian ^t   Kerin, Michael J ^u   Miller, Nicola ^u   Marme, Frederik ^v   Schneeweiss, Andreas ^v   Sohn, Christof ^v   Burwinkel, Barbara ^v,w   Guénel, Pascal ^x,y   Truong, Thérèse ^x,y   Laurent Puig, Pierre ^z   Menegaux, Florence ^x,y   Bojesen, Stig E ^aa   Nordestgaard, Børge G ^aa   Nielsen, Sune F ^aa   Flyger, Henrik ^aa   Milne, Roger L ^h   Zamora, M Pilar ^ab   Arias Perez, Jose Ignacio ^ac   Benitez, Javier ^h,ad   Anton Culver, Hoda ^ae   Brenner, Hermann ^w   Müller, Heiko ^w   Arndt, Volker ^w   Stegmaier, Christa ^af   Meindl, Alfons ^ag   Lichtner, Peter ^ah   Schmutzler, Rita K ^ai   Engel, Christoph ^aj   Brauch, Hiltrud ^ak,al   Hamann, Ute ^{w,am,an,ao,ap}   Justenhoven, Christina ^ak,al   Aaltonen, Kirsimari ^d   Heikkilä, Päivi ^d   Aittomäki, Kristiina ^d   Blomqvist, Carl ^d   Matsuo, Keitaro ^aq   Ito, Hidemi ^aq   Iwata, Hiroji ^aq   Sueta, Aiko ^aq   Bogdanova, Natalia V ^ar   Antonenkova, Natalia N ^as   Dörk, Thilo ^ar   Lindblom, Annika ^at   Margolin, Sara ^at   Mannermaa, Arto ^au,av   Kataja, Vesa ^au,av,aw   Kosma, Veli Matti ^au,av   Hartikainen, Jaana M ^au,av   Wu, Anna H ^ax   Tseng, Chiu Chen ^ax   Van Den Berg, David ^ax   Stram, Daniel O ^ax   Lambrechts, Diether ^ay,az   Peeters, Stephanie ^ba   Smeets, Ann ^ba   Floris, Giuseppe ^ba   Chang Claude, Jenny ^w   Rudolph, Anja ^w   Nickels, Stefan ^w   Flesch Janys, Dieter ^w,bb   Radice, Paolo ^bc,bd   Peterlongo, Paolo ^bc,bd   Bonanni, Bernardo ^be   Sardella, Domenico ^bd   Couch, Fergus J ^bf   Wang, Xianshu ^bf   Pankratz, Vernon S ^bf   Lee, Adam ^bg   Giles, Graham G ^j,bh   Severi, Gianluca ^j,bh   Baglietto, Laura ^j,bh   Haiman, Christopher A ^ax   Henderson, Brian E ^ax   Schumacher, Fredrick ^ax   Le Marchand, Loic ^bi   Simard, Jacques ^bj   Goldberg, Mark S ^i,bk   Labrèche, France ^bl   Dumont, Martine ^bj   Teo, Soo Hwang ^bm,bn   Yip, Cheng Har ^bn   Ng, Char Hong ^bn   Vithana, Eranga Nishanthie ^bo   Kristensen, Vessela ^bp,bq   Zheng, Wei ^br   Deming Halverson, Sandra ^br   Shrubsole, Martha ^br   Long, Jirong ^br   Winqvist, Robert ^bs   Pylkäs, Katri ^bs   Jukkola Vuorinen, Arja ^bt   Grip, Mervi ^bt   Andrulis, Irene L ^bu,bv   Knight, Julia A ^bv,bw   Glendon, Gord ^bv   Mulligan, Anna Marie ^bu,bx   Devilee, Peter ^by   Seynaeve, Caroline ^bz   García Closas, Montserrat ^r   Figueroa, Jonine ^ca   Chanock, Stephen J ^ca   Lissowska, Jolanta ^cb   Czene, Kamila ^at   Klevebring, Daniel ^at   Schoof, Nils ^at   Hooning, Maartje J ^bz   Martens, John W M ^bz   Collée, J Margriet ^bz   Tilanus Linthorst, Madeleine ^bz   Hall, Per ^at   Li, Jingmei ^cc   Liu, Jianjun ^cc   Humphreys, Keith ^at   Shu, Xiao Ou ^br   Lu, Wei ^cd   Gao, Yu Tang ^ce   Cai, Hui ^br   Cox, Angela ^cf   Balasubramanian, Sabapathy P ^cf   Blot, William ^br,cg   Signorello, Lisa B ^br,cg   Cai, Qiuyin ^br   Pharoah, Paul D P ^b   Healey, Catherine S ^b   Shah, Mitul ^b   Pooley, Karen A ^b   Kang, Daehee ^ch   Yoo, Keun Young ^ch   Noh, Dong Young ^ch   Hartman, Mikael ^ci,cj   Miao, Hui ^cj   Sng, Jen Hwei ^ci   Sim, Xueling ^cj   Jakubowska, Anna ^ck   Lubinski, Jan ^ck   Jaworska Bieniek, Katarzyna ^ck,cl   Durda, Katarzyna ^ck   Sangrajrang, Suleeporn ^cm   Gaborieau, Valerie ^cn   McKay, James ^cn   Toland, Amanda E ^co   Ambrosone, Christine B ^cp   Yannoukakos, Drakoulis ^cq   Godwin, Andrew K ^cr   Shen, Chen Yang ^cs,ct   Hsiung, Chia Ni ^ct   Wu, Pei Ei ^ct   Chen, Shou Tung ^cu   Swerdlow, Anthony ^r   Ashworth, Alan ^r   Orr, Nick ^r   Schoemaker, Minouk J ^r   Ponder, Bruce A J ^c   Nevanlinna, Heli ^d   Brown, Melissa A ^a   Chenevix Trench, Georgia ^e   Easton, Douglas F ^b   Dunning, Alison M ^b   more..

^a UNIVERSITY OF QUEENSLAND   (Australia)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^c CANCER RESEARCH UK CAMBRIDGE RESEARCH INSTITUTE   (United Kingdom)

^d UNIVERSITY OF HELSINKI   (Finland)

^e QIMR BERGHOFER MEDICAL RESEARCH INSTITUTE   (Australia)

^f BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

^g HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^h Centro Nacional de Investigaciones Oncológicas   (Spain)

ⁱ MCGILL UNIVERSITY   (Canada)

^j UNIVERSITY OF MELBOURNE   (Australia)

^k ANTONI VAN LEEUWENHOEK HOSPITAL   (Netherlands)

^l UNIVERSITY OF WARWICK   (United Kingdom)

^m MINISTRY OF PUBLIC HEALTH   (Thailand)

ⁿ UNIVERSITY OF CALIFORNIA   (United States)

^o UNIVERSITY HOSPITAL ERLANGEN   (Germany)

^p UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

^q LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE   (United Kingdom)

^r INSTITUTE OF CANCER RESEARCH   (United Kingdom)

^s GUY'S AND ST THOMAS' NHS FOUNDATION TRUST   (United Kingdom)

^t UNIVERSITY OF OXFORD   (United Kingdom)

^u UNIVERSITY HOSPITAL GALWAY   (Ireland)

^v UNIVERSITY OF HEIDELBERG   (Germany)

^w GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^x NATIONAL INSTITUTES OF HEALTH   (United States)

^y UNIVERSITÉ PARIS SACLAY   (France)

^z Therapeutic Implications Laboratoire d'Excellence GR Ex   (France)

^aa GENTOFTE UNIVERSITY HOSPITAL   (Denmark)

^ab HOSPITAL UNIVERSITARIO LA PAZ   (Spain)

^ac HOSPITAL MONTE NARANCO   (Spain)

^ad CENTRO DE INVESTIGACIÓN BIOMÉDICA EN RED DE ENFERMEDADES RARAS CIBERER   (Spain)

^ae UNIVERSITY OF CALIFORNIA   (United States)

^af Saarland Cancer Registry   (Germany)

^ag TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^ah INSTITUTE OF EPIDEMIOLOGY   (Germany)

^ai UNIVERSITY OF COLOGNE   (Germany)

^aj UNIVERSITY OF LEIPZIG   (Germany)

^ak DR MARGARETE FISCHER BOSCH INSTITUTE OF CLINICAL PHARMACOLOGY   (Germany)

^al UNIVERSITY OF TÜBINGEN   (Germany)

^am Johanniter Krankenhaus   (Germany)

^an SAARLAND UNIVERSITY   (Germany)

^ao INSTITUT DER RUHR UNIVERSITÄT BOCHUM IPA   (Germany)

^ap UNIVERSITY OF BONN   (Germany)

^aq AICHI CANCER CENTER HOSPITAL   (Japan)

^ar HANNOVER MEDICAL SCHOOL   (Germany)

^as Research Institute of Oncology and Medical Radiology of the Ministry of Health of the Byelorussian SSR   (Belarus)

^at KAROLINSKA INSTITUTE   (Sweden)

^au KUOPIO UNIVERSITY HOSPITAL   (Finland)

^av UNIVERSITY OF EASTERN FINLAND   (Finland)

^aw PETER MACCALLUM CANCER CENTRE   (Australia)

^ax UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^ay UNIVERSITY OF LEUVEN   (Belgium)

^az DEPARTMENT OF PLANT SYSTEMS BIOLOGY   (Belgium)

^ba UNIVERSITY HOSPITALS LEUVEN   (Belgium)

^bb UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

^bc NATIONAL CANCER INSTITUTE   (Italy)

^bd FIRC INSTITUTE OF MOLECULAR ONCOLOGY   (Italy)

^be EUROPEAN INSTITUTE OF ONCOLOGY   (Italy)

^bf MAYO CLINIC   (United States)

^bg MAYO GRADUATE SCHOOL   (United States)

^bh CANCER EPIDEMIOLOGY CENTRE   (Australia)

^bi UNIVERSITY OF HAWAII CANCER CENTER   (United States)

^bj LAVAL UNIVERSITY   (Canada)

^bk ROYAL VICTORIA HOSPITAL   (Canada)

^bl UNIVERSITÉ DE MONTRÉAL   (Canada)

^bm CANCER RESEARCH INITIATIVES FOUNDATION   (Malaysia)

^bn UNIVERSITY OF MALAYA   (Malaysia)

^bo SINGAPORE EYE RESEARCH INSTITUTE   (Singapore)

^bp OSLO UNIVERSITY HOSPITAL   (Norway)

^bq UNIVERSITY OF OSLO   (Norway)

^br VANDERBILT INGRAM CANCER CENTER   (United States)

^bs UNIVERSITY OF OULU   (Finland)

^bt OULU UNIVERSITY HOSPITAL   (Finland)

^bu UNIVERSITY OF TORONTO   (Canada)

^bv MOUNT SINAI HOSPITAL   (Canada)

^bw UNIVERSITY OF TORONTO   (Canada)

^bx UNIVERSITY HEALTH NETWORK   (Canada)

^by LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^bz ERASMUS MEDICAL CENTER   (Netherlands)

^ca NATIONAL CANCER INSTITUTE   (United States)

^cb INSTITUTE OF ONCOLOGY   (Poland)

^cc GENOME INSTITUTE OF SINGAPORE   (Singapore)

^cd Shanghai Center for Disease Control and Prevention   (China)

^ce SHANGHAI CANCER INSTITUTE   (China)

^cf UNIVERSITY OF SHEFFIELD   (United Kingdom)

^cg INTERNATIONAL EPIDEMIOLOGY INSTITUTE   (United States)

^ch Seoul National University   (South Korea)

^ci NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^cj NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^ck POMERANIAN MEDICAL UNIVERSITY   (Poland)

^cl MEDICAL UNIVERSITY OF WARSAW   (Poland)

^cm NATIONAL CANCER INSTITUTE   (Thailand)

^cn INTERNATIONAL AGENCY FOR RESEARCH ON CANCER   (France)

^co OHIO STATE UNIVERSITY   (United States)

^cp ROSWELL PARK CANCER INSTITUTE   (United States)

^cq INSTITUTE OF NANOSCIENCE AND NANOTECHNOLOGY   (Greece)

^cr UNIVERSITY OF KANSAS SCHOOL OF MEDICINE   (United States)

^cs CHINA MEDICAL UNIVERSITY   (Taiwan)

^ct INSTITUTE OF BIOMEDICAL SCIENCES   (Taiwan)

^cu CHANGHUA CHRISTIAN HOSPITAL   (Taiwan)

more..

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN D1; TRANSCRIPTION FACTOR ELK 4; TRANSCRIPTION FACTOR GATA 3;

ALLELE; ANTIGEN EXPRESSION; ARTICLE; BREAST CANCER; CANCER RISK; CHROMATIN IMMUNOPRECIPITATION; ENZYME ACTIVITY; GENE MAPPING; HUMAN; PRIORITY JOURNAL; SILENCER ELEMENT;

BINDING SITES; BREAST NEOPLASMS; CASE-CONTROL STUDIES; CELL LINE, TUMOR; CHROMATIN; CHROMATIN IMMUNOPRECIPITATION; CHROMOSOMES, HUMAN, PAIR 11; CYCLIN D1; ELECTROPHORETIC MOBILITY SHIFT ASSAY; ENHANCER ELEMENTS, GENETIC; ETS-DOMAIN PROTEIN ELK-4; FEMALE; GATA3 TRANSCRIPTION FACTOR; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; LUCIFERASES; POLYMORPHISM, SINGLE NUCLEOTIDE; PROMOTER REGIONS, GENETIC; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; RNA, SMALL INTERFERING; SILENCER ELEMENTS, TRANSCRIPTIONAL;

EID: 84875933011     PISSN: 00029297     EISSN: 15376605     Source Type: Journal    
DOI: 10.1016/j.ajhg.2013.01.002     Document Type: Article

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