Rare loss-of-function variants in SETD1A are associated with schizophrenia and developmental disorders

Nature Neuroscience

Volumn 19, Issue 4, 2016, Pages 571-577

  Singh, Tarjinder ^a   Kurki, Mitja I ^b,c   Curtis, David ^d   Purcell, Shaun M ^e   Crooks, Lucy ^a,f   McRae, Jeremy ^a   Suvisaari, Jaana ^g   Chheda, Himanshu ^b   Blackwood, Douglas ^h   Breen, Gerome ⁱ   Pietilinen, Olli ^a,b,g   Gerety, Sebastian S ^a   Ayub, Muhammad ^j   Blyth, Moira ^k   Cole, Trevor ^l   Collier, David ^i,m   Coomber, Eve L ^a   Craddock, Nick ⁿ   Daly, Mark J ^c   Danesh, John ^a,o   DiForti, Marta ⁱ   Foster, Alison ^p   Freimer, Nelson B ^q   Geschwind, Daniel ^r   Johnstone, Mandy ^h   Joss, Shelagh ^s   Kirov, Georg ⁿ   Körkkö, Jarmo ^t   Kuismin, Outi ^u   Holmans, Peter ⁿ   Hultman, Christina M ^v   Iyegbe, Conrad ⁱ   Lönnqvist, Jouko ^g   Mnnikkö, Minna ^u   McCarroll, Steve A ^c,w   McGuffin, Peter ⁱ   McIntosh, Andrew M ^h   McQuillin, Andrew ^d   Moilanen, Jukka S ^u   Moore, Carmel ^o   Murray, Robin M ⁱ   Newbury Ecob, Ruth ^x   Ouwehand, Willem ^a,o,y   Paunio, Tiina ^b,g   Prigmore, Elena ^a   Rees, Elliott ⁿ   Roberts, David ^o,aa,ab   Sambrook, Jennifer ^o   Sklar, Pamela ^e   St Clair, David ^ac   Veijola, Juha ^t   Walters, James T R ⁿ   Williams, Hywel ⁿ   Sullivan, Patrick F ^v,z   Hurles, Matthew E ^a   O'Donovan, Michael C ⁿ   Palotie, Aarno ^a,b,c   Owen, Michael J ^a   Barrett, Jeffrey C ^a   more..

^a WELLCOME TRUST SANGER INSTITUTE   (United Kingdom)

^b UNIVERSITY OF HELSINKI   (Finland)

^c BROAD INSTITUTE OF MIT AND HARVARD   (United States)

^d UNIVERSITY COLLEGE LONDON   (United Kingdom)

^e MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^f SHEFFIELD CHILDREN'S NHS FOUNDATION TRUST   (United Kingdom)

^g NATIONAL PUBLIC HEALTH INSTITUTE   (Finland)

^h UNIVERSITY OF EDINBURGH   (United Kingdom)

ⁱ KING'S COLLEGE LONDON   (United Kingdom)

^j QUEEN S UNIVERSITY   (Canada)

^k CHAPEL ALLERTON HOSPITAL   (United Kingdom)

^l BIRMINGHAM WOMEN S HOSPITAL   (United Kingdom)

^m ELI LILLY AND COMPANY   (United States)

ⁿ CARDIFF UNIVERSITY   (United Kingdom)

^o UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^p BIRMINGHAM CHILDREN S HOSPITAL NHS FOUNDATION TRUST   (United Kingdom)

^q UNIVERSITY OF CALIFORNIA   (United States)

^r UNIVERSITY OF CALIFORNIA   (United States)

^s QUEEN ELIZABETH UNIVERSITY HOSPITAL   (United Kingdom)

^t OULU UNIVERSITY HOSPITAL   (Finland)

^u UNIVERSITY OF OULU   (Finland)

^v KAROLINSKA INSTITUTE   (Sweden)

^w HARVARD MEDICAL SCHOOL   (United States)

^x ST MICHAEL'S HOSPITAL   (United Kingdom)

^y NHS BLOOD AND TRANSPLANT   (United Kingdom)

^z UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^aa JOHN RADCLIFFE HOSPITAL   (United Kingdom)

^ab UNIVERSITY OF OXFORD   (United Kingdom)

^ac UNIVERSITY OF ABERDEEN   (United Kingdom)

more..

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ARTICLE; CONTROLLED STUDY; DEVELOPMENTAL DISORDER; EPIGENETICS; EXOME; GENE SEQUENCE; GENETIC ASSOCIATION; GENETIC VARIABILITY; HETEROZYGOTE; HISTONE METHYLATION; HUMAN; LEARNING DISORDER; LOSS OF FUNCTION MUTATION; MAJOR CLINICAL STUDY; NEUROPSYCHIATRY; OBSERVATIONAL STUDY; PHENOTYPE; PRIORITY JOURNAL; SCHIZOPHRENIA; CASE CONTROL STUDY; COHORT ANALYSIS; FEMALE; FINLAND; GENETIC ASSOCIATION STUDY; GENETIC PREDISPOSITION; GENETIC VARIATION; GENETICS; MALE; NEURODEVELOPMENTAL DISORDERS; PROCEDURES;

HISTONE LYSINE METHYLTRANSFERASE; SETD1A PROTEIN, HUMAN;

CASE-CONTROL STUDIES; COHORT STUDIES; FEMALE; FINLAND; GENETIC ASSOCIATION STUDIES; GENETIC PREDISPOSITION TO DISEASE; GENETIC VARIATION; HISTONE-LYSINE N-METHYLTRANSFERASE; HUMANS; MALE; NEURODEVELOPMENTAL DISORDERS; SCHIZOPHRENIA;

EID: 84962233946     PISSN: 10976256     EISSN: 15461726     Source Type: Journal    
DOI: 10.1038/nn.4267     Document Type: Article

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