A rare mutation of CACNA1C in a patient with bipolar disorder, and decreased gene expression associated with a bipolar-associated common SNP of CACNA1C in brain

Molecular Psychiatry

Volumn 19, Issue 8, 2014, Pages 890-894

  Gershon, E S ^a   Grennan, K ^a   Busnello, J ^a   Badner, J A ^a   Ovsiew, F ^a   Memon, S ^b   Alliey Rodriguez, N ^a   Cooper, J ^a   Romanos, B ^c   Liu, C ^c,d  

^a UNIVERSITY OF CHICAGO   (United States)

^b NORTHWESTERN UNIVERSITY   (United States)

^c UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

^d CENTRAL SOUTH UNIVERSITY   (China)

Author keywords

bipolar disorder; CACNA1C; calcium channel blockers; long QT syndrome; Timothy syndrome

Indexed keywords

CITALOPRAM; UNCLASSIFIED DRUG; VERAPAMIL; VOLTAGE GATED CALCIUM CHANNEL; VOLTAGE GATED CALCIUM CHANNEL CAV.1; CACNA1C PROTEIN, HUMAN; CALCIUM CHANNEL L TYPE;

ADULT; ARTICLE; BIPOLAR DISORDER; BRAIN INJURY; CALCIUM TRANSPORT; CASE REPORT; COMA; DEPRESSION; EUROPEAN AMERICAN; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENE FREQUENCY; GENETIC ASSOCIATION; GENOTYPE; HEART ARREST; HEART ATRIUM FIBRILLATION; HEART VENTRICLE FIBRILLATION; HEMIPARESIS; HOSPITALIZATION; HUMAN; HYPOMANIA; IMPLANTABLE CARDIOVERTER DEFIBRILLATOR; LIVER FAILURE; LONG QT SYNDROME; MAJOR DEPRESSION; MALE; MANIA; MISSENSE MUTATION; MOLECULAR PATHOLOGY; NEUROLOGIST; PRIORITY JOURNAL; QT INTERVAL; QUANTITATIVE TRAIT LOCUS; QUANTITATIVE TRAIT LOCUS MAPPING; RESTLESSNESS; SEIZURE; SINGLE NUCLEOTIDE POLYMORPHISM; SINUS NODE; SPECIAL EDUCATION; WORK; AUTISM; BIOSYNTHESIS; BRAIN; CEREBELLUM; COMPLICATION; DOWN REGULATION; GENETIC PREDISPOSITION; GENETICS; METABOLISM; MUTATION; PARIETAL LOBE; SYNDACTYLY;

ADULT; AUTISTIC DISORDER; BIPOLAR DISORDER; BRAIN; CALCIUM CHANNELS, L-TYPE; CEREBELLUM; DOWN-REGULATION; GENE EXPRESSION PROFILING; GENETIC PREDISPOSITION TO DISEASE; HUMANS; LONG QT SYNDROME; MALE; MUTATION; PARIETAL LOBE; POLYMORPHISM, SINGLE NUCLEOTIDE; QUANTITATIVE TRAIT LOCI; SYNDACTYLY;

EID: 84905023068     PISSN: 13594184     EISSN: 14765578     Source Type: Journal    
DOI: 10.1038/mp.2013.107     Document Type: Article

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