-
1
-
-
67249117049
-
Potential etiologic and functional implications of genome-wide association loci for human diseases and traits
-
Hindorff,L.A., Sethupathy,P., Junkins,H.A., Ramos,E.M., Mehta,J.P., Collins,F.S. and Manolio,T.A. (2009) Potential etiologic and functional implications of genome-wide association loci for human diseases and traits. Proc. Natl Acad. Sci. USA, 106, 9362-9367.
-
(2009)
Proc. Natl Acad. Sci. USA
, vol.106
, pp. 9362-9367
-
-
Hindorff, L.A.1
Sethupathy, P.2
Junkins, H.A.3
Ramos, E.M.4
Mehta, J.P.5
Collins, F.S.6
Manolio, T.A.7
-
2
-
-
84975742565
-
A map of human genome variation from population-scale sequencing
-
Consortium,T.G.P. (2010) A map of human genome variation from population-scale sequencing. Nature, 467, 1061-1073.
-
(2010)
Nature
, vol.467
, pp. 1061-1073
-
-
Consortium, T.G.P.1
-
3
-
-
79957604678
-
Principles for the post-GWAS functional characterization of cancer risk loci
-
Freedman,M.L., Monteiro,A.N., Gayther,S.A., Coetzee,G.A., Risch,A., Plass,C., Casey,G., De Biasi,M., Carlson,C., Duggan,D. et al. (2011) Principles for the post-GWAS functional characterization of cancer risk loci. Nat. Genet., 43, 513-518.
-
(2011)
Nat. Genet.
, vol.43
, pp. 513-518
-
-
Freedman, M.L.1
Monteiro, A.N.2
Gayther, S.A.3
Coetzee, G.A.4
Risch, A.5
Plass, C.6
Casey, G.7
De Biasi, M.8
Carlson, C.9
Duggan, D.10
-
4
-
-
81255134093
-
Beyond genome-wide association studies: New strategies for identifying genetic determinants of hypertension
-
Wang,X., Prins,B.P., Sober,S., Laan,M. and Snieder,H. (2011) Beyond genome-wide association studies: New strategies for identifying genetic determinants of hypertension. Curr. Hypertens. Rep., 13, 442-451.
-
(2011)
Curr. Hypertens. Rep.
, vol.13
, pp. 442-451
-
-
Wang, X.1
Prins, B.P.2
Sober, S.3
Laan, M.4
Snieder, H.5
-
5
-
-
74949137308
-
A systematic approach to understand the functional consequences of non-protein coding risk regions
-
Coetzee,G.A., Jia,L., Frenkel,B., Henderson,B.E., Tanay,A., Haiman,C.A. and Freedman,M.L. (2010) A systematic approach to understand the functional consequences of non-protein coding risk regions. Cell Cycle, 9, 47-51.
-
(2010)
Cell Cycle
, vol.9
, pp. 47-51
-
-
Coetzee, G.A.1
Jia, L.2
Frenkel, B.3
Henderson, B.E.4
Tanay, A.5
Haiman, C.A.6
Freedman, M.L.7
-
6
-
-
79955583542
-
Mapping and analysis of chromatin state dynamics in nine human cell types
-
Ernst,J., Kheradpour,P., Mikkelsen,T.S., Shoresh,N., Ward,L.D.,-epstein, C.B., Zhang,X., Wang,L., Issner,R., Coyne,M. et al. (2011) Mapping and analysis of chromatin state dynamics in nine human cell types. Nature, 473, 43-49.
-
(2011)
Nature
, vol.473
, pp. 43-49
-
-
Ernst, J.1
Kheradpour, P.2
Mikkelsen, T.S.3
Shoresh, N.4
Ward, L.D.5
Epstein, C.B.6
Zhang, X.7
Wang, L.8
Issner, R.9
Coyne, M.10
-
7
-
-
70249128376
-
Functional enhancers at the gene-poor 8q24 cancer-linked locus
-
Jia,L., Landan,G., Pomerantz,M., Jaschek,R., Herman,P., Reich,D., Yan,C., Khalid,O., Kantoff,P., Oh,W. et al. (2009) Functional enhancers at the gene-poor 8q24 cancer-linked locus. PLoS Genet., 5,-e1000597.
-
(2009)
PLoS Genet.
, vol.5
-
-
Jia, L.1
Landan, G.2
Pomerantz, M.3
Jaschek, R.4
Herman, P.5
Reich, D.6
Yan, C.7
Khalid, O.8
Kantoff, P.9
Oh, W.10
-
8
-
-
63149133163
-
Fine mapping association study and functional analysis implicate a SNP in MSMB at 10q11 as a causal variant for prostate cancer risk
-
Chang,B.L., Cramer,S.D., Wiklund,F., Isaacs,S.D., Stevens,V.L., Sun,J., Smith,S., Pruett,K., Romero,L.M., Wiley,K.E. et al. (2009) Fine mapping association study and functional analysis implicate a SNP in MSMB at 10q11 as a causal variant for prostate cancer risk. Hum. Mol. Genet., 18, 1368-1375.
-
(2009)
Hum. Mol. Genet.
, vol.18
, pp. 1368-1375
-
-
Chang, B.L.1
Cramer, S.D.2
Wiklund, F.3
Isaacs, S.D.4
Stevens, V.L.5
Sun, J.6
Smith, S.7
Pruett, K.8
Romero, L.M.9
Wiley, K.E.10
-
9
-
-
74049103101
-
Genome-wide association studies in cancer: Current and future directions
-
Chung,C.C., Magalhaes,W.C., Gonzalez-Bosquet,J. and Chanock,S.J. (2010) Genome-wide association studies in cancer: Current and future directions. Carcinogenesis, 31, 111-120.
-
(2010)
Carcinogenesis
, vol.31
, pp. 111-120
-
-
Chung, C.C.1
Magalhaes, W.C.2
Gonzalez-Bosquet, J.3
Chanock, S.J.4
-
10
-
-
77952567987
-
Simple combinations of lineage-determining transcription factors prime cis-regulatory elements required for macrophage and B cell identities
-
Heinz,S., Benner,C., Spann,N., Bertolino,E., Lin,Y.C., Laslo,P., Cheng,J.X., Murre,C., Singh,H. and Glass,C.K. (2010) Simple combinations of lineage-determining transcription factors prime cis-regulatory elements required for macrophage and B cell identities. Mol. Cell, 38, 576-589.
-
(2010)
Mol. Cell
, vol.38
, pp. 576-589
-
-
Heinz, S.1
Benner, C.2
Spann, N.3
Bertolino, E.4
Lin, Y.C.5
Laslo, P.6
Cheng, J.X.7
Murre, C.8
Singh, H.9
Glass, C.K.10
-
11
-
-
78049359286
-
Genomics. 1000 Genomes Project gives new map of genetic diversity
-
Pennisi,E. (2010) Genomics. 1000 Genomes Project gives new map of genetic diversity. Science, 330, 574-575.
-
(2010)
Science
, vol.330
, pp. 574-575
-
-
Pennisi, E.1
-
12
-
-
33747824819
-
PupaSuite: Finding functional single nucleotide polymorphisms for large-scale genotyping purposes
-
Conde,L., Vaquerizas,J.M., Dopazo,H., Arbiza,L., Reumers,J., Rousseau,F., Schymkowitz,J. and Dopazo,J. (2006) PupaSuite: Finding functional single nucleotide polymorphisms for large-scale genotyping purposes. Nucleic Acids Res., 34, W621-W625.
-
(2006)
Nucleic Acids Res.
, vol.34
-
-
Conde, L.1
Vaquerizas, J.M.2
Dopazo, H.3
Arbiza, L.4
Reumers, J.5
Rousseau, F.6
Schymkowitz, J.7
Dopazo, J.8
-
13
-
-
84861090227
-
SNPeffect 4.0: On-line prediction of molecular and structural effects of protein-coding variants
-
De Baets,G., Van Durme,J., Reumers,J., Maurer-Stroh,S., Vanhee,P., Dopazo,J., Schymkowitz,J. and Rousseau,F. (2012) SNPeffect 4.0: On-line prediction of molecular and structural effects of protein-coding variants. Nucleic Acids Res., 40, D935-D939.
-
(2012)
Nucleic Acids Res.
, vol.40
-
-
De Baets, G.1
Van Durme, J.2
Reumers, J.3
Maurer-Stroh, S.4
Vanhee, P.5
Dopazo, J.6
Schymkowitz, J.7
Rousseau, F.8
-
14
-
-
79955550445
-
A user's guide to the encyclopedia of DNA elements (ENCODE
-
Myers,R.M., Stamatoyannopoulos,J., Snyder,M., Dunham,I., Hardison,R.C., Bernstein,B.E., Gingeras,T.R., Kent,W.J., Birney,E., Wold,B. et al. (2011) A user's guide to the encyclopedia of DNA elements (ENCODE). PLoS Biol., 9,-e1001046.
-
(2011)
PLoS Biol.
, vol.9
-
-
Myers, R.M.1
Stamatoyannopoulos, J.2
Snyder, M.3
Dunham, I.4
Hardison, R.C.5
Bernstein, B.E.6
Gingeras, T.R.7
Kent, W.J.8
Birney, E.9
Wold, B.10
-
15
-
-
77953808473
-
Next-generation genomics: An integrative approach
-
Hawkins,R.D., Hon,G.C. and Ren,B. (2010) Next-generation genomics: An integrative approach. Nat. Rev. Genet., 11, 476-486.
-
(2010)
Nat. Rev. Genet.
, vol.11
, pp. 476-486
-
-
Hawkins, R.D.1
Hon, G.C.2
Ren, B.3
-
16
-
-
84862917808
-
Genome architectures revealed by tethered chromosome conformation capture and population-based modeling
-
Kalhor,R., Tjong,H., Jayathilaka,N., Alber,F. and Chen,L. (2011) Genome architectures revealed by tethered chromosome conformation capture and population-based modeling. Nat. Biotechnol., 30, 90-98.
-
(2011)
Nat. Biotechnol.
, vol.30
, pp. 90-98
-
-
Kalhor, R.1
Tjong, H.2
Jayathilaka, N.3
Alber, F.4
Chen, L.5
-
17
-
-
84655162785
-
Regions of focal DNA hypermethylation and long-range hypomethylation in colorectal cancer coincide with nuclear lamina-Associated domains
-
Berman,B.P., Weisenberger,D.J., Aman,J.F., Hinoue,T., Ramjan,Z., Liu,Y., Noushmehr,H., Lange,C.P., van Dijk,C.M., Tollenaar,R.A. et al. (2011) Regions of focal DNA hypermethylation and long-range hypomethylation in colorectal cancer coincide with nuclear lamina-Associated domains. Nat. Genet., 44, 40-46.
-
(2011)
Nat. Genet.
, vol.44
, pp. 40-46
-
-
Berman, B.P.1
Weisenberger, D.J.2
Aman, J.F.3
Hinoue, T.4
Ramjan, Z.5
Liu, Y.6
Noushmehr, H.7
Lange, C.P.8
Van Dijk, C.M.9
Tollenaar, R.A.10
-
18
-
-
70449711243
-
Computation for ChIP-seq and RNA-seq studies
-
Pepke,S., Wold,B. and Mortazavi,A. (2009) Computation for ChIP-seq and RNA-seq studies. Nat. Methods, 6, S22-S32.
-
(2009)
Nat. Methods
, vol.6
-
-
Pepke, S.1
Wold, B.2
Mortazavi, A.3
-
19
-
-
84856435413
-
Transcriptional networks and chromatin remodeling controlling adipogenesis
-
Siersbaek,R., Nielsen,R. and Mandrup,S. (2012) Transcriptional networks and chromatin remodeling controlling adipogenesis. Trends Endocrinol. Metab., 23, 56-64.
-
(2012)
Trends Endocrinol. Metab.
, vol.23
, pp. 56-64
-
-
Siersbaek, R.1
Nielsen, R.2
Mandrup, S.3
-
20
-
-
80053539409
-
Open chromatin defined by DNaseI and FAIRE identifies regulatory elements that shape cell-Type identity
-
Song,L., Zhang,Z., Grasfeder,L.L., Boyle,A.P., Giresi,P.G., Lee,B.K., Sheffield,N.C., Graf,S., Huss,M., Keefe,D. et al. (2011) Open chromatin defined by DNaseI and FAIRE identifies regulatory elements that shape cell-Type identity. Genome Res., 21, 1757-1767.
-
(2011)
Genome Res.
, vol.21
, pp. 1757-1767
-
-
Song, L.1
Zhang, Z.2
Grasfeder, L.L.3
Boyle, A.P.4
Giresi, P.G.5
Lee, B.K.6
Sheffield, N.C.7
Graf, S.8
Huss, M.9
Keefe, D.10
-
21
-
-
77957940722
-
The NIH roadmap epigenomics mapping consortium
-
Bernstein,B.E., Stamatoyannopoulos,J.A., Costello,J.F., Ren,B., Milosavljevic,A., Meissner,A., Kellis,M., Marra,M.A., Beaudet,A.L.,-ecker,J.R. et al. (2010) The NIH Roadmap Epigenomics Mapping Consortium. Nat. Biotechnol., 28, 1045-1048.
-
(2010)
Nat. Biotechnol.
, vol.28
, pp. 1045-1048
-
-
Bernstein, B.E.1
Stamatoyannopoulos, J.A.2
Costello, J.F.3
Ren, B.4
Milosavljevic, A.5
Meissner, A.6
Kellis, M.7
Marra, M.A.8
Beaudet, A.L.9
Ecker, J.R.10
-
22
-
-
77952108366
-
Identification of a CpG island methylator phenotype that defines a distinct subgroup of glioma
-
Noushmehr,H., Weisenberger,D.J., Diefes,K., Phillips,H.S., Pujara,K., Berman,B.P., Pan,F., Pelloski,C.E., Sulman,E.P., Bhat,K.P. et al. (2010) Identification of a CpG island methylator phenotype that defines a distinct subgroup of glioma. Cancer Cell, 17, 510-522.
-
(2010)
Cancer Cell
, vol.17
, pp. 510-522
-
-
Noushmehr, H.1
Weisenberger, D.J.2
Diefes, K.3
Phillips, H.S.4
Pujara, K.5
Berman, B.P.6
Pan, F.7
Pelloski, C.E.8
Sulman, E.P.9
Bhat, K.P.10
-
23
-
-
79959699992
-
CTCF-mediated functional chromatin interactome in pluripotent cells
-
Handoko,L., Xu,H., Li,G., Ngan,C.Y., Chew,E., Schnapp,M., Lee,C.W., Ye,C., Ping,J.L., Mulawadi,F. et al. (2011) CTCF-mediated functional chromatin interactome in pluripotent cells. Nat. Genet., 43, 630-638.
-
(2011)
Nat. Genet.
, vol.43
, pp. 630-638
-
-
Handoko, L.1
Xu, H.2
Li, G.3
Ngan, C.Y.4
Chew, E.5
Schnapp, M.6
Lee, C.W.7
Ye, C.8
Ping, J.L.9
Mulawadi, F.10
-
24
-
-
83255164884
-
Comprehensive genome-wide protein-DNA interactions detected at single-nucleotide resolution
-
Rhee,H.S. and Pugh,B.F. (2011) Comprehensive genome-wide protein-DNA interactions detected at single-nucleotide resolution. Cell, 147, 1408-1419.
-
(2011)
Cell
, vol.147
, pp. 1408-1419
-
-
Rhee, H.S.1
Pugh, B.F.2
-
25
-
-
80054756754
-
Genomic maps of long noncoding RNA occupancy reveal principles of RNA-chromatin interactions
-
Chu,C., Qu,K., Zhong,F.L., Artandi,S.E. and Chang,H.Y. (2011) Genomic maps of long noncoding RNA occupancy reveal principles of RNA-chromatin interactions. Mol. Cell, 44, 667-678.
-
(2011)
Mol. Cell
, vol.44
, pp. 667-678
-
-
Chu, C.1
Qu, K.2
Zhong, F.L.3
Artandi, S.E.4
Chang, H.Y.5
-
26
-
-
80054880084
-
DNA methylation directly silences genes with non-CpG island promoters and establishes a nucleosome occupied promoter
-
Han,H., Cortez,C.C., Yang,X., Nichols,P.W., Jones,P.A. and Liang,G. (2011) DNA methylation directly silences genes with non-CpG island promoters and establishes a nucleosome occupied promoter. Hum. Mol. Genet., 20, 4299-4310.
-
(2011)
Hum. Mol. Genet.
, vol.20
, pp. 4299-4310
-
-
Han, H.1
Cortez, C.C.2
Yang, X.3
Nichols, P.W.4
Jones, P.A.5
Liang, G.6
-
27
-
-
68149180890
-
Genome-wide association study identifies five susceptibility loci for glioma
-
Shete,S., Hosking,F.J., Robertson,L.B., Dobbins,S.E., Sanson,M., Malmer,B., Simon,M., Marie,Y., Boisselier,B., Delattre,J.Y. et al. (2009) Genome-wide association study identifies five susceptibility loci for glioma. Nat. Genet., 41, 899-904.
-
(2009)
Nat. Genet.
, vol.41
, pp. 899-904
-
-
Shete, S.1
Hosking, F.J.2
Robertson, L.B.3
Dobbins, S.E.4
Sanson, M.5
Malmer, B.6
Simon, M.7
Marie, Y.8
Boisselier, B.9
Delattre, J.Y.10
-
28
-
-
68149180891
-
Variants in the CDKN2B and RTEL1 regions are associated with high-grade glioma susceptibility
-
Wrensch,M., Jenkins,R.B., Chang,J.S., Yeh,R.F., Xiao,Y., Decker,P.A., Ballman,K.V., Berger,M., Buckner,J.C., Chang,S. et al. (2009) Variants in the CDKN2B and RTEL1 regions are associated with high-grade glioma susceptibility. Nat. Genet., 41, 905-908.
-
(2009)
Nat. Genet.
, vol.41
, pp. 905-908
-
-
Wrensch, M.1
Jenkins, R.B.2
Chang, J.S.3
Yeh, R.F.4
Xiao, Y.5
Decker, P.A.6
Ballman, K.V.7
Berger, M.8
Buckner, J.C.9
Chang, S.10
-
29
-
-
77953610367
-
Genetic advances in glioma: Susceptibility genes and networks
-
Liu,Y., Shete,S., Hosking,F., Robertson,L., Houlston,R. and Bondy,M. (2010) Genetic advances in glioma: Susceptibility genes and networks. Curr. Opin. Genet. Dev., 20, 239-244.
-
(2010)
Curr. Opin. Genet. Dev.
, vol.20
, pp. 239-244
-
-
Liu, Y.1
Shete, S.2
Hosking, F.3
Robertson, L.4
Houlston, R.5
Bondy, M.6
-
30
-
-
78049455961
-
Genetic risk profiles identify different molecular etiologies for glioma
-
Simon,M., Hosking,F.J., Marie,Y., Gousias,K., Boisselier,B., Carpentier,C., Schramm,J., Mokhtari,K., Hoang-Xuan,K., Idbaih,A. et al. (2010) Genetic risk profiles identify different molecular etiologies for glioma. Clin. Cancer Res., 16, 5252-5259.
-
(2010)
Clin. Cancer Res.
, vol.16
, pp. 5252-5259
-
-
Simon, M.1
Hosking, F.J.2
Marie, Y.3
Gousias, K.4
Boisselier, B.5
Carpentier, C.6
Schramm, J.7
Mokhtari, K.8
Hoang-Xuan, K.9
Idbaih, A.10
-
31
-
-
28744458859
-
Bioconductor: Open software development for computational biology and bioinformatics
-
Gentleman,R.C., Carey,V.J., Bates,D.M., Bolstad,B., Dettling,M., Dudoit,S.,-ellis,B., Gautier,L., Ge,Y., Gentry,J. et al. (2004) Bioconductor: Open software development for computational biology and bioinformatics. Genome Biol., 5, R80.
-
(2004)
Genome Biol.
, vol.5
-
-
Gentleman, R.C.1
Carey, V.J.2
Bates, D.M.3
Bolstad, B.4
Dettling, M.5
Dudoit, S.6
Ellis, B.7
Gautier, L.8
Ge, Y.9
Gentry, J.10
-
32
-
-
84861397707
-
Picking ChIP-seq peak detectors for analyzing chromatin modification experiments
-
Micsinai,M., Parisi,F., Strino,F., Asp,P., Dynlacht,B.D. and Kluger,Y. (2012) Picking ChIP-seq peak detectors for analyzing chromatin modification experiments. Nucleic Acids Res., 40,-e70.
-
(2012)
Nucleic Acids Res.
, vol.40
-
-
Micsinai, M.1
Parisi, F.2
Strino, F.3
Asp, P.4
Dynlacht, B.D.5
Kluger, Y.6
-
33
-
-
34249848791
-
Systematic discovery of regulatory motifs in conserved regions of the human genome, including thousands of CTCF insulator sites
-
Xie,X., Mikkelsen,T.S., Gnirke,A., Lindblad-Toh,K., Kellis,M. and Lander,E.S. (2007) Systematic discovery of regulatory motifs in conserved regions of the human genome, including thousands of CTCF insulator sites. Proc. Natl Acad. Sci. USA, 104, 7145-7150.
-
(2007)
Proc. Natl Acad. Sci. USA
, vol.104
, pp. 7145-7150
-
-
Xie, X.1
Mikkelsen, T.S.2
Gnirke, A.3
Lindblad-Toh, K.4
Kellis, M.5
Lander, E.S.6
-
34
-
-
43749105558
-
Linkage disequilibrium-understanding the evolutionary past and mapping the medical future
-
Slatkin,M. (2008) Linkage disequilibrium-understanding the evolutionary past and mapping the medical future. Nat. Rev. Genet., 9, 477-485.
-
(2008)
Nat. Rev. Genet.
, vol.9
, pp. 477-485
-
-
Slatkin, M.1
-
35
-
-
77951947707
-
ChIPpeakAnno: A Bioconductor package to annotate ChIP-seq and ChIP-chip data
-
Zhu,L.J., Gazin,C., Lawson,N.D., Pages,H., Lin,S.M., Lapointe,D.S. and Green,M.R. (2010) ChIPpeakAnno: A Bioconductor package to annotate ChIP-seq and ChIP-chip data. BMC Bioinformatics, 11, 237.
-
(2010)
BMC Bioinformatics
, vol.11
, pp. 237
-
-
Zhu, L.J.1
Gazin, C.2
Lawson, N.D.3
Pages, H.4
Lin, S.M.5
Lapointe, D.S.6
Green, M.R.7
-
36
-
-
0035866822
-
Soluble decoy receptor 3 is expressed by malignant gliomas and suppresses CD95 ligand-induced apoptosis and chemotaxis
-
Roth,W., Isenmann,S., Nakamura,M., Platten,M., Wick,W., Kleihues,P., Bahr,M., Ohgaki,H., Ashkenazi,A. and Weller,M. (2001) Soluble decoy receptor 3 is expressed by malignant gliomas and suppresses CD95 ligand-induced apoptosis and chemotaxis. Cancer Res., 61, 2759-2765.
-
(2001)
Cancer Res.
, vol.61
, pp. 2759-2765
-
-
Roth, W.1
Isenmann, S.2
Nakamura, M.3
Platten, M.4
Wick, W.5
Kleihues, P.6
Bahr, M.7
Ohgaki, H.8
Ashkenazi, A.9
Weller, M.10
|