A human-specific AS3MT isoform and BORCS7 are molecular risk factors in the 10q24.32 schizophrenia-associated locus

Nature Medicine

Volumn 22, Issue 6, 2016, Pages 649-656

  Li, Ming ^a   Jaffe, Andrew E ^a,b   Straub, Richard E ^a   Tao, Ran ^a   Shin, Joo Heon ^a   Wang, Yanhong ^a   Chen, Qiang ^a   Li, Chao ^a   Jia, Yankai ^a   Ohi, Kazutaka ^a   Maher, Brady J ^a,b,c   Brandon, Nicholas J ^d   Cross, Alan ^d   Chenoweth, Joshua G ^a   Hoeppner, Daniel J ^a   Wei, Huijun ^a   Hyde, Thomas M ^a,c   McKay, Ronald ^a   Kleinman, Joel E ^a,c   Weinberger, Daniel R ^a,c  

^a JOHNS HOPKINS UNIVERSITY   (United States)

^b JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

^c JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d ASTRAZENECA   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; ARSENIC TRIOXIDE; ARSENITE METHYLTRANSFERASE; BLOC 1 RELATED COMPLEX SUBUNIT 7 PROTEIN; COMPLEMENTARY DNA; ISOPROTEIN; METHYLTRANSFERASE; PROTEIN; RECOMBINANT PROTEIN; UNCLASSIFIED DRUG; AS3MT PROTEIN, HUMAN; C10ORF32 PROTEIN, HUMAN; CARRIER PROTEIN; MESSENGER RNA;

ADULT; ALLELE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ASTROCYTE; BRAIN DEVELOPMENT; CELL DIFFERENTIATION; CELL FATE; CONTROLLED STUDY; DNA METHYLATION; ENZYME ACTIVITY; EXON; GENE EXPRESSION; GENE LOCUS; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; GENETIC RISK; GENOME-WIDE ASSOCIATION STUDY; GENOTYPE; HUMAN; HUMAN TISSUE; LUCIFERASE ASSAY; MAJOR CLINICAL STUDY; MOLECULAR BIOLOGY; NERVE CELL; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; RAT; RISK ASSESSMENT; RISK FACTOR; RNA SEQUENCE; SCHIZOPHRENIA; SINGLE NUCLEOTIDE POLYMORPHISM; STEM CELL; UPREGULATION; VARIABLE NUMBER OF TANDEM REPEAT; ADOLESCENT; AFRICAN AMERICAN; BIPOLAR DISORDER; BRAIN; CAUCASIAN; CHILD; CHROMOSOME 10; FEMALE; GENE EXPRESSION PROFILING; GENETIC PREDISPOSITION; GENETICS; MAJOR DEPRESSION; MALE; METABOLISM; MIDDLE AGED; NERVOUS SYSTEM DEVELOPMENT; PRESCHOOL CHILD; YOUNG ADULT;

ADOLESCENT; ADULT; AFRICAN AMERICANS; ALLELES; ASTROCYTES; BIPOLAR DISORDER; BRAIN; CARRIER PROTEINS; CHILD; CHILD, PRESCHOOL; CHROMOSOMES, HUMAN, PAIR 10; DEPRESSIVE DISORDER, MAJOR; DNA METHYLATION; EUROPEAN CONTINENTAL ANCESTRY GROUP; FEMALE; GENE EXPRESSION PROFILING; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; MALE; METHYLTRANSFERASES; MIDDLE AGED; MINISATELLITE REPEATS; NEUROGENESIS; NEURONS; POLYMORPHISM, GENETIC; POLYMORPHISM, SINGLE NUCLEOTIDE; PROTEIN ISOFORMS; RNA, MESSENGER; SCHIZOPHRENIA; YOUNG ADULT;

EID: 84966657282     PISSN: 10788956     EISSN: 1546170X     Source Type: Journal    
DOI: 10.1038/nm.4096     Document Type: Article

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