Aberrant TAL1 activation is mediated by an interchromosomal interaction in human T-cell acute lymphoblastic leukemia

Leukemia

Volumn 28, Issue 2, 2014, Pages 349-361

  Patel, B ^a   Kang, Y ^a,b   Cui, K ^c   Litt, M ^d   Riberio, M S J ^a   Deng, C ^a   Salz, T ^a   Casada, S ^d   Fu, X ^b   Qiu, Y ^a,e   Zhao, K ^c   Huang, S ^a,e  

^a UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

^b JILIN UNIVERSITY   (China)

^c NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

^d BALL STATE UNIVERSITY   (United States)

^e UNIVERSITY OF FLORIDA   (United States)

Author keywords

chromatin loops; CTCF insulator; epigenetic regulation; T cell leukemia; TAL1 SCL oncogene

Indexed keywords

HISTONE H3; TRANSCRIPTION FACTOR CTCF; TRANSCRIPTION FACTOR TAL1;

ACUTE LYMPHOBLASTIC LEUKEMIA; ARTICLE; CELL PROLIFERATION; CELLS; CHROMATIN STRUCTURE; CHROMOSOME 16; CONTROLLED STUDY; ERYTHROID CELL; GENE EXPRESSION; HEMATOPOIESIS; HEMATOPOIETIC CELL; HISTONE METHYLATION; HUMAN; HUMAN CELL; LEUKEMIA CELL; PRIORITY JOURNAL;

BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; CELL LINE, TUMOR; CHROMATIN; CHROMOSOMES, HUMAN, PAIR 16; ENHANCER ELEMENTS, GENETIC; EPISTASIS, GENETIC; ERYTHROID PRECURSOR CELLS; GENE EXPRESSION REGULATION, LEUKEMIC; GENE ORDER; GENETIC LOCI; HEMATOPOIESIS; HISTONE-LYSINE N-METHYLTRANSFERASE; HISTONES; HUMANS; ORGAN SPECIFICITY; P300-CBP TRANSCRIPTION FACTORS; PRECURSOR T-CELL LYMPHOBLASTIC LEUKEMIA-LYMPHOMA; PROMOTER REGIONS, GENETIC; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-MAF; REGULATORY SEQUENCES, NUCLEIC ACID; REPRESSOR PROTEINS; TRANSCRIPTIONAL ACTIVATION;

EID: 84893788391     PISSN: 08876924     EISSN: 14765551     Source Type: Journal    
DOI: 10.1038/leu.2013.158     Document Type: Article

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