Cis-acting regulation of brain-specific ANK3 gene expression by a genetic variant associated with bipolar disorder

Molecular Psychiatry

Volumn 18, Issue 8, 2013, Pages 922-929

  Rueckert, E H ^a,b,c   Barker, D ^c   Ruderfer, D ^a,b,c,d   Bergen, S E ^a,b,c   O'dushlaine, C ^c   Luce, C J ^c   Sheridan, S D ^a,b   Theriault, K M ^a,b   Chambert, K ^c   Moran, J ^c   Purcell, S M ^a,b,c,d   Madison, J M ^c   Haggarty, S J ^a,b,c   Sklar, P ^d  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c BROAD INSTITUTE OF MIT AND HARVARD   (United States)

^d MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

ANK3; Ankyrin G (AnkG); axon initial segment; bipolar disorder; human neurons; stem cells

Indexed keywords

ANKYRIN; ANKYRIN 3; CIS ACTING ELEMENT; COMPLEMENTARY DNA; MESSENGER RNA; RNA LIGASE; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ARTICLE; BIPOLAR DISORDER; BRAIN REGION; CEREBELLUM; CINGULATE GYRUS; CONTROLLED STUDY; DISEASE ASSOCIATION; EXON; FRONTAL CORTEX; GENE AMPLIFICATION; GENE EXPRESSION; GENETIC ASSOCIATION; GENETIC TRANSCRIPTION; GENETIC VARIABILITY; GENOTYPE; HAPLOTYPE; HOMOZYGOTE; HUMAN; HUMAN CELL; HUMAN TISSUE; NERVE CELL; NEURAL STEM CELL; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; PROTEIN DOMAIN; REGULATORY MECHANISM; SINGLE NUCLEOTIDE POLYMORPHISM; TRANSCRIPTION INITIATION SITE;

ALLELES; ANKYRINS; BIPOLAR DISORDER; BRAIN; CELLS, CULTURED; EXONS; FETUS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENETIC PREDISPOSITION TO DISEASE; HUMANS; NEURONS; POLYMORPHISM, SINGLE NUCLEOTIDE; PROTEIN ISOFORMS; STEM CELLS;

EID: 84881187768     PISSN: 13594184     EISSN: 14765578     Source Type: Journal    
DOI: 10.1038/mp.2012.104     Document Type: Article

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