메뉴 건너뛰기




Volumn 74, Issue , 2017, Pages 356-365

Life stress, glucocorticoid signaling, and the aging epigenome: Implications for aging-related diseases

Author keywords

Aging; Cancer; Cardiovascular disease; Dementia; DNA methylation; Epigenetics; Glucocorticoid signaling; Stress

Indexed keywords

GLUCOCORTICOID; HISTONE;

EID: 85004140679     PISSN: 01497634     EISSN: 18737528     Source Type: Journal    
DOI: 10.1016/j.neubiorev.2016.06.003     Document Type: Review
Times cited : (94)

References (147)
  • 2
    • 0030026713 scopus 로고    scopus 로고
    • Molecular determinants of glucocorticoid receptor function and tissue sensitivity to glucocorticoids
    • Bamberger, C.M., Schulte, H.M., Chrousos, G.P., Molecular determinants of glucocorticoid receptor function and tissue sensitivity to glucocorticoids. Endocr. Rev. 17 (1996), 245–261.
    • (1996) Endocr. Rev. , vol.17 , pp. 245-261
    • Bamberger, C.M.1    Schulte, H.M.2    Chrousos, G.P.3
  • 3
    • 80054850054 scopus 로고    scopus 로고
    • Chronic restraint stress in adolescence differentially influences hypothalamic-pituitary-adrenal axis function and adult hippocampal neurogenesis in male and female rats
    • Barha, C.K., Brummelte, S., Lieblich, S.E., Galea, L.A., Chronic restraint stress in adolescence differentially influences hypothalamic-pituitary-adrenal axis function and adult hippocampal neurogenesis in male and female rats. Hippocampus 21 (2011), 1216–1227.
    • (2011) Hippocampus , vol.21 , pp. 1216-1227
    • Barha, C.K.1    Brummelte, S.2    Lieblich, S.E.3    Galea, L.A.4
  • 5
    • 84942294112 scopus 로고    scopus 로고
    • Epigenetic regulation of ageing: linking environmental inputs to genomic stability
    • Benayoun, B.A., Pollina, E.A., Brunet, A., Epigenetic regulation of ageing: linking environmental inputs to genomic stability. Nat. Rev. Mol. Cell Biol. 16 (2015), 593–610.
    • (2015) Nat. Rev. Mol. Cell Biol. , vol.16 , pp. 593-610
    • Benayoun, B.A.1    Pollina, E.A.2    Brunet, A.3
  • 6
    • 84857525459 scopus 로고    scopus 로고
    • Dynamic regulation of glucocorticoid signalling in health and disease
    • Biddie, S.C., Conway-Campbell, B.L., Lightman, S.L., Dynamic regulation of glucocorticoid signalling in health and disease. Rheumatology (Oxford) 51 (2012), 403–412.
    • (2012) Rheumatology (Oxford) , vol.51 , pp. 403-412
    • Biddie, S.C.1    Conway-Campbell, B.L.2    Lightman, S.L.3
  • 13
    • 79958729836 scopus 로고    scopus 로고
    • Glucocorticoids induce long-lasting effects in neural stem cells resulting in senescence-related alterations
    • Bose, R., Moors, M., Tofighi, R., Cascante, A., Hermanson, O., Ceccatelli, S., Glucocorticoids induce long-lasting effects in neural stem cells resulting in senescence-related alterations. Cell. Death. Dis., 1, 2010, e92.
    • (2010) Cell. Death. Dis. , vol.1 , pp. e92
    • Bose, R.1    Moors, M.2    Tofighi, R.3    Cascante, A.4    Hermanson, O.5    Ceccatelli, S.6
  • 15
    • 79958021241 scopus 로고    scopus 로고
    • Behavioral effects of chronic adolescent stress are sustained and sexually dimorphic
    • Bourke, C.H., Neigh, G.N., Behavioral effects of chronic adolescent stress are sustained and sexually dimorphic. Horm. Behav. 60 (2011), 112–120.
    • (2011) Horm. Behav. , vol.60 , pp. 112-120
    • Bourke, C.H.1    Neigh, G.N.2
  • 16
    • 85001610245 scopus 로고    scopus 로고
    • Frailty is associated with the epigenetic clock but not with telomere length in a German cohort
    • Breitling, L.P., Saum, K.U., Perna, L., Schottker, B., Holleczek, B., Brenner, H., Frailty is associated with the epigenetic clock but not with telomere length in a German cohort. Clin. Epigenet., 8, 2016, 21.
    • (2016) Clin. Epigenet. , vol.8 , pp. 21
    • Breitling, L.P.1    Saum, K.U.2    Perna, L.3    Schottker, B.4    Holleczek, B.5    Brenner, H.6
  • 17
    • 84963699425 scopus 로고    scopus 로고
    • Supportive family environments ameliorate the link between racial discrimination and epigenetic aging: a replication across two longitudinal cohorts
    • Brody, G.H., Miller, G.E., Yu, T., Beach, S.R., Chen, E., Supportive family environments ameliorate the link between racial discrimination and epigenetic aging: a replication across two longitudinal cohorts. Psychol. Sci. 27 (2016), 530–541.
    • (2016) Psychol. Sci. , vol.27 , pp. 530-541
    • Brody, G.H.1    Miller, G.E.2    Yu, T.3    Beach, S.R.4    Chen, E.5
  • 18
    • 84951771704 scopus 로고    scopus 로고
    • Family-centered prevention ameliorates the longitudinal association between risky family processes and epigenetic aging
    • Brody, G.H., Yu, T., Chen, E., Beach, S.R., Miller, G.E., Family-centered prevention ameliorates the longitudinal association between risky family processes and epigenetic aging. J. Child Psychol. Psychiatry 57 (2016), 566–574.
    • (2016) J. Child Psychol. Psychiatry , vol.57 , pp. 566-574
    • Brody, G.H.1    Yu, T.2    Chen, E.3    Beach, S.R.4    Miller, G.E.5
  • 19
  • 20
    • 84924292417 scopus 로고    scopus 로고
    • Extrapolating histone marks across developmental stages, tissues, and species: an enhancer prediction case study
    • Capra, J.A., Extrapolating histone marks across developmental stages, tissues, and species: an enhancer prediction case study. BMC Genomics, 16, 2015, 104.
    • (2015) BMC Genomics , vol.16 , pp. 104
    • Capra, J.A.1
  • 22
    • 33644904316 scopus 로고    scopus 로고
    • Chronic stress at work and the metabolic syndrome: prospective study
    • Chandola, T., Brunner, E., Marmot, M., Chronic stress at work and the metabolic syndrome: prospective study. BMJ 332 (2006), 521–525.
    • (2006) BMJ , vol.332 , pp. 521-525
    • Chandola, T.1    Brunner, E.2    Marmot, M.3
  • 24
    • 0026536665 scopus 로고
    • The concepts of stress and stress system disorders: overview of physical and behavioral homeostasis
    • Chrousos, G.P., Gold, P.W., The concepts of stress and stress system disorders: overview of physical and behavioral homeostasis. JAMA 267 (1992), 1244–1252.
    • (1992) JAMA , vol.267 , pp. 1244-1252
    • Chrousos, G.P.1    Gold, P.W.2
  • 25
    • 33746851204 scopus 로고    scopus 로고
    • Assessment of HPA-axis function in posttraumatic stress disorder: pharmacological and non-pharmacological challenge tests, a review
    • de Kloet, C.S., Vermetten, E., Geuze, E., Kavelaars, A., Heijnen, C.J., Westenberg, H.G., Assessment of HPA-axis function in posttraumatic stress disorder: pharmacological and non-pharmacological challenge tests, a review. J. Psychiatr. Res. 40 (2006), 550–567.
    • (2006) J. Psychiatr. Res. , vol.40 , pp. 550-567
    • de Kloet, C.S.1    Vermetten, E.2    Geuze, E.3    Kavelaars, A.4    Heijnen, C.J.5    Westenberg, H.G.6
  • 26
    • 84923005662 scopus 로고    scopus 로고
    • Changes in the leukocyte methylome and its effect on cardiovascular-related genes after exercise
    • Denham, J., O'Brien, B.J., Marques, F.Z., Charchar, F.J., Changes in the leukocyte methylome and its effect on cardiovascular-related genes after exercise. J. Appl. Physiol. 118 (2015), 475–488.
    • (2015) J. Appl. Physiol. , vol.118 , pp. 475-488
    • Denham, J.1    O'Brien, B.J.2    Marques, F.Z.3    Charchar, F.J.4
  • 27
    • 0033712280 scopus 로고    scopus 로고
    • Squirrel monkey immunophilin FKBP51 is a potent inhibitor of glucocorticoid receptor binding
    • Denny, W.B., Valentine, D.L., Reynolds, P.D., Smith, D.F., Scammell, J.G., Squirrel monkey immunophilin FKBP51 is a potent inhibitor of glucocorticoid receptor binding. Endocrinology 141 (2000), 4107–4113.
    • (2000) Endocrinology , vol.141 , pp. 4107-4113
    • Denny, W.B.1    Valentine, D.L.2    Reynolds, P.D.3    Smith, D.F.4    Scammell, J.G.5
  • 28
    • 84940383352 scopus 로고    scopus 로고
    • RelB/p52-associated CBP/HDAC1 mediate acetylation/de-acetylation of H3K9 to upregulate CRH in term human placenta
    • Di Stefano, V., Wang, B., Parobchak, N., Roche, N., Rosen, T., RelB/p52-associated CBP/HDAC1 mediate acetylation/de-acetylation of H3K9 to upregulate CRH in term human placenta. Sci. Signal., 8(391), 2015, ra85.
    • (2015) Sci. Signal. , vol.8 , Issue.391 , pp. ra85
    • Di Stefano, V.1    Wang, B.2    Parobchak, N.3    Roche, N.4    Rosen, T.5
  • 33
    • 84894269481 scopus 로고    scopus 로고
    • Early life stress and later health outcomes–findings from the Helsinki Birth Cohort Study
    • Eriksson, M., Raikkonen, K., Eriksson, J.G., Early life stress and later health outcomes–findings from the Helsinki Birth Cohort Study. Am. J. Hum. Biol. 26 (2014), 111–116.
    • (2014) Am. J. Hum. Biol. , vol.26 , pp. 111-116
    • Eriksson, M.1    Raikkonen, K.2    Eriksson, J.G.3
  • 34
    • 78650958717 scopus 로고    scopus 로고
    • Life stress and losses and deficit in adulthood as breast cancer risk factor: a prospective case-control study in Kuopio, Finland
    • Eskelinen, M., Ollonen, P., Life stress and losses and deficit in adulthood as breast cancer risk factor: a prospective case-control study in Kuopio, Finland. In Vivo 24 (2010), 899–904.
    • (2010) In Vivo , vol.24 , pp. 899-904
    • Eskelinen, M.1    Ollonen, P.2
  • 35
    • 84905375992 scopus 로고    scopus 로고
    • Chronic stress, depressive symptoms, anger, hostility, and risk of stroke and transient ischemic attack in the multi-ethnic study of atherosclerosis
    • Everson-Rose, S.A., Roetker, N.S., Lutsey, P.L., Kershaw, K.N., Longstreth, W.T. Jr., Sacco, R.L., Diez Roux, A.V., Alonso, A., Chronic stress, depressive symptoms, anger, hostility, and risk of stroke and transient ischemic attack in the multi-ethnic study of atherosclerosis. Stroke 45 (2014), 2318–2323.
    • (2014) Stroke , vol.45 , pp. 2318-2323
    • Everson-Rose, S.A.1    Roetker, N.S.2    Lutsey, P.L.3    Kershaw, K.N.4    Longstreth, W.T.5    Sacco, R.L.6    Diez Roux, A.V.7    Alonso, A.8
  • 37
    • 84894088246 scopus 로고    scopus 로고
    • Cross-sectional and longitudinal changes in DNA methylation with age: an epigenome-wide analysis revealing over 60 novel age-associated CpG sites
    • Florath, I., Butterbach, K., Muller, H., Bewerunge-Hudler, M., Brenner, H., Cross-sectional and longitudinal changes in DNA methylation with age: an epigenome-wide analysis revealing over 60 novel age-associated CpG sites. Hum. Mol. Genet. 23 (2014), 1186–1201.
    • (2014) Hum. Mol. Genet. , vol.23 , pp. 1186-1201
    • Florath, I.1    Butterbach, K.2    Muller, H.3    Bewerunge-Hudler, M.4    Brenner, H.5
  • 39
    • 68149183508 scopus 로고    scopus 로고
    • Genetic and epigenetic regulation of aging
    • Fraga, M.F., Genetic and epigenetic regulation of aging. Curr. Opin. Immunol. 21 (2009), 446–453.
    • (2009) Curr. Opin. Immunol. , vol.21 , pp. 446-453
    • Fraga, M.F.1
  • 42
    • 84866525407 scopus 로고    scopus 로고
    • Psychological distress as a risk factor for death from cerebrovascular disease
    • Hamer, M., Kivimaki, M., Stamatakis, E., Batty, G.D., Psychological distress as a risk factor for death from cerebrovascular disease. CMAJ 184 (2012), 1461–1466.
    • (2012) CMAJ , vol.184 , pp. 1461-1466
    • Hamer, M.1    Kivimaki, M.2    Stamatakis, E.3    Batty, G.D.4
  • 43
    • 84962023392 scopus 로고    scopus 로고
    • Interindividual methylomic variation across blood, cortex, and cerebellum: implications for epigenetic studies of neurological and neuropsychiatric phenotypes
    • Hannon, E., Lunnon, K., Schalkwyk, L., Mill, J., Interindividual methylomic variation across blood, cortex, and cerebellum: implications for epigenetic studies of neurological and neuropsychiatric phenotypes. Epigenetics 10 (2015), 1024–1032.
    • (2015) Epigenetics , vol.10 , pp. 1024-1032
    • Hannon, E.1    Lunnon, K.2    Schalkwyk, L.3    Mill, J.4
  • 46
    • 38349131059 scopus 로고    scopus 로고
    • The dexamethasone/corticotropin-releasing factor test in men with major depression: role of childhood trauma
    • Heim, C., Mletzko, T., Purselle, D., Musselman, D.L., Nemeroff, C.B., The dexamethasone/corticotropin-releasing factor test in men with major depression: role of childhood trauma. Biol. Psychiatry 63 (2008), 398–405.
    • (2008) Biol. Psychiatry , vol.63 , pp. 398-405
    • Heim, C.1    Mletzko, T.2    Purselle, D.3    Musselman, D.L.4    Nemeroff, C.B.5
  • 47
    • 46249091103 scopus 로고    scopus 로고
    • The link between childhood trauma and depression: insights from HPA axis studies in humans
    • Heim, C., Newport, D.J., Mletzko, T., Miller, A.H., Nemeroff, C.B., The link between childhood trauma and depression: insights from HPA axis studies in humans. Psychoneuroendocrinology 33 (2008), 693–710.
    • (2008) Psychoneuroendocrinology , vol.33 , pp. 693-710
    • Heim, C.1    Newport, D.J.2    Mletzko, T.3    Miller, A.H.4    Nemeroff, C.B.5
  • 51
    • 77952678006 scopus 로고    scopus 로고
    • Epigenetic control of neural precursor cell fate during development
    • Hirabayashi, Y., Gotoh, Y., Epigenetic control of neural precursor cell fate during development. Nat. Rev. Neurosci. 11 (2010), 377–388.
    • (2010) Nat. Rev. Neurosci. , vol.11 , pp. 377-388
    • Hirabayashi, Y.1    Gotoh, Y.2
  • 52
    • 84886111619 scopus 로고    scopus 로고
    • DNA methylation age of human tissues and cell types
    • Horvath, S., DNA methylation age of human tissues and cell types. Genome Biol., 14, 2013, R115.
    • (2013) Genome Biol. , vol.14 , pp. R115
    • Horvath, S.1
  • 53
    • 84957539650 scopus 로고    scopus 로고
    • Increased epigenetic age and granulocyte counts in the blood of Parkinson's disease patients
    • Horvath, S., Ritz, B.R., Increased epigenetic age and granulocyte counts in the blood of Parkinson's disease patients. Aging (Milano) 7:12 (2015), 1130–1142.
    • (2015) Aging (Milano) , vol.7 , Issue.12 , pp. 1130-1142
    • Horvath, S.1    Ritz, B.R.2
  • 57
    • 84892909863 scopus 로고    scopus 로고
    • Aging and epigenetic drift: a vicious cycle
    • Issa, J.P., Aging and epigenetic drift: a vicious cycle. J. Clin. Invest. 124 (2014), 24–29.
    • (2014) J. Clin. Invest. , vol.124 , pp. 24-29
    • Issa, J.P.1
  • 60
    • 84901236374 scopus 로고    scopus 로고
    • No association between mean telomere length and life stress observed in a 30 year birth cohort
    • Jodczyk, S., Fergusson, D.M., Horwood, L.J., Pearson, J.F., Kennedy, M.A., No association between mean telomere length and life stress observed in a 30 year birth cohort. PLoS One, 9, 2014, e97102.
    • (2014) PLoS One , vol.9 , pp. e97102
    • Jodczyk, S.1    Fergusson, D.M.2    Horwood, L.J.3    Pearson, J.F.4    Kennedy, M.A.5
  • 61
    • 33847065486 scopus 로고    scopus 로고
    • The epigenomics of cancer
    • Jones, P.A., Baylin, S.B., The epigenomics of cancer. Cell 128 (2007), 683–692.
    • (2007) Cell , vol.128 , pp. 683-692
    • Jones, P.A.1    Baylin, S.B.2
  • 62
    • 84954379553 scopus 로고    scopus 로고
    • DNA methylation and healthy human aging
    • Jones, M.J., Goodman, S.J., Kobor, M.S., DNA methylation and healthy human aging. Aging Cell 14:16 (2015), 924–932.
    • (2015) Aging Cell , vol.14 , Issue.16 , pp. 924-932
    • Jones, M.J.1    Goodman, S.J.2    Kobor, M.S.3
  • 63
    • 84866912460 scopus 로고    scopus 로고
    • Hypothalamic-pituitary-adrenal axis and cardiovascular disease
    • P. Hjemdahl A. Rosengren A. Steptoe Springer London, UK
    • Kaltsas, G., Zannas, A.S., Chrousos, G.P., Hypothalamic-pituitary-adrenal axis and cardiovascular disease. Hjemdahl, P., Rosengren, A., Steptoe, A., (eds.) Stress and Cardiovascular Disease, 2012, Springer, London, UK.
    • (2012) Stress and Cardiovascular Disease
    • Kaltsas, G.1    Zannas, A.S.2    Chrousos, G.P.3
  • 64
    • 77955551671 scopus 로고    scopus 로고
    • Childhood adversities are associated with shorter telomere length at adult age both in individuals with an anxiety disorder and controls
    • Kananen, L., Surakka, I., Pirkola, S., Suvisaari, J., Lonnqvist, J., Peltonen, L., Ripatti, S., Hovatta, I., Childhood adversities are associated with shorter telomere length at adult age both in individuals with an anxiety disorder and controls. PLoS One, 5, 2010, e10826.
    • (2010) PLoS One , vol.5 , pp. e10826
    • Kananen, L.1    Surakka, I.2    Pirkola, S.3    Suvisaari, J.4    Lonnqvist, J.5    Peltonen, L.6    Ripatti, S.7    Hovatta, I.8
  • 65
    • 81955161814 scopus 로고    scopus 로고
    • Psychobiological allostasis: resistance, resilience and vulnerability
    • Karatsoreos, I.N., McEwen, B.S., Psychobiological allostasis: resistance, resilience and vulnerability. Trends Cogn. Sci. 15 (2011), 576–584.
    • (2011) Trends Cogn. Sci. , vol.15 , pp. 576-584
    • Karatsoreos, I.N.1    McEwen, B.S.2
  • 66
    • 84926648676 scopus 로고    scopus 로고
    • FKBP5 allele-specific epigenetic modification in gene by environment interaction
    • Klengel, T., Binder, E.B., FKBP5 allele-specific epigenetic modification in gene by environment interaction. Neuropsychopharmacology 40 (2015), 244–246.
    • (2015) Neuropsychopharmacology , vol.40 , pp. 244-246
    • Klengel, T.1    Binder, E.B.2
  • 68
    • 80855144438 scopus 로고    scopus 로고
    • Epigenetic-aging-signature to determine age in different tissues
    • Koch, C.M., Wagner, W., Epigenetic-aging-signature to determine age in different tissues. Aging (Milano) 3 (2011), 1018–1027.
    • (2011) Aging (Milano) , vol.3 , pp. 1018-1027
    • Koch, C.M.1    Wagner, W.2
  • 70
    • 84908156860 scopus 로고    scopus 로고
    • Does epigenetic drift contribute to age-related increases in breast cancer risk?
    • Langevin, S.M., Pinney, S.M., Leung, Y.K., Ho, S.M., Does epigenetic drift contribute to age-related increases in breast cancer risk?. Epigenomics 6 (2014), 367–369.
    • (2014) Epigenomics , vol.6 , pp. 367-369
    • Langevin, S.M.1    Pinney, S.M.2    Leung, Y.K.3    Ho, S.M.4
  • 73
    • 84908346393 scopus 로고    scopus 로고
    • FKBP5 and CRHR1 polymorphisms moderate the stress-physical health association in a national sample
    • Lessard, J., Holman, E.A., FKBP5 and CRHR1 polymorphisms moderate the stress-physical health association in a national sample. Health Psychol. 33 (2014), 1046–1056.
    • (2014) Health Psychol. , vol.33 , pp. 1046-1056
    • Lessard, J.1    Holman, E.A.2
  • 74
    • 81955164243 scopus 로고    scopus 로고
    • Early life stress triggers sustained changes in histone deacetylase expression and histone H4 modifications that alter responsiveness to adolescent antidepressant treatment
    • Levine, A., Worrell, T.R., Zimnisky, R., Schmauss, C., Early life stress triggers sustained changes in histone deacetylase expression and histone H4 modifications that alter responsiveness to adolescent antidepressant treatment. Neurobiol. Dis. 45 (2012), 488–498.
    • (2012) Neurobiol. Dis. , vol.45 , pp. 488-498
    • Levine, A.1    Worrell, T.R.2    Zimnisky, R.3    Schmauss, C.4
  • 75
    • 84943372238 scopus 로고    scopus 로고
    • DNA methylation age of blood predicts future onset of lung cancer in the women's health initiative
    • Levine, M.E., Hosgood, H.D., Chen, B., Absher, D., Assimes, T., Horvath, S., DNA methylation age of blood predicts future onset of lung cancer in the women's health initiative. Aging (Milano) 7 (2015), 690–700.
    • (2015) Aging (Milano) , vol.7 , pp. 690-700
    • Levine, M.E.1    Hosgood, H.D.2    Chen, B.3    Absher, D.4    Assimes, T.5    Horvath, S.6
  • 76
    • 84957568353 scopus 로고    scopus 로고
    • Epigenetic age of the pre-frontal cortex is associated with neuritic plaques, amyloid load, and Alzheimer's disease related cognitive functioning
    • Levine, M.E., Lu, A.T., Bennett, D.A., Horvath, S., Epigenetic age of the pre-frontal cortex is associated with neuritic plaques, amyloid load, and Alzheimer's disease related cognitive functioning. Aging (Milano) 7:12 (2015), 1198–1211.
    • (2015) Aging (Milano) , vol.7 , Issue.12 , pp. 1198-1211
    • Levine, M.E.1    Lu, A.T.2    Bennett, D.A.3    Horvath, S.4
  • 77
    • 77649342230 scopus 로고    scopus 로고
    • Age-dependent decreases in DNA methyltransferase levels and low transmethylation micronutrient levels synergize to promote overexpression of genes implicated in autoimmunity and acute coronary syndromes
    • Li, Y., Liu, Y., Strickland, F.M., Richardson, B., Age-dependent decreases in DNA methyltransferase levels and low transmethylation micronutrient levels synergize to promote overexpression of genes implicated in autoimmunity and acute coronary syndromes. Exp. Gerontol. 45 (2010), 312–322.
    • (2010) Exp. Gerontol. , vol.45 , pp. 312-322
    • Li, Y.1    Liu, Y.2    Strickland, F.M.3    Richardson, B.4
  • 78
    • 84948973859 scopus 로고    scopus 로고
    • Genome-wide alterations in hippocampal 5-hydroxymethylcytosine links plasticity genes to acute stress
    • Li, S., Papale, L.A., Zhang, Q., Madrid, A., Chen, L., Chopra, P., Keles, S., Jin, P., Alisch, R.S., Genome-wide alterations in hippocampal 5-hydroxymethylcytosine links plasticity genes to acute stress. Neurobiol. Dis. 86 (2015), 99–108.
    • (2015) Neurobiol. Dis. , vol.86 , pp. 99-108
    • Li, S.1    Papale, L.A.2    Zhang, Q.3    Madrid, A.4    Chen, L.5    Chopra, P.6    Keles, S.7    Jin, P.8    Alisch, R.S.9
  • 79
    • 84901701041 scopus 로고    scopus 로고
    • Association between informal caregiving and cellular aging in the survey of the health of wisconsin: the role of caregiving characteristics, stress, and strain
    • Litzelman, K., Witt, W.P., Gangnon, R.E., Nieto, F.J., Engelman, C.D., Mailick, M.R., Skinner, H.G., Association between informal caregiving and cellular aging in the survey of the health of wisconsin: the role of caregiving characteristics, stress, and strain. Am. J. Epidemiol. 179 (2014), 1340–1352.
    • (2014) Am. J. Epidemiol. , vol.179 , pp. 1340-1352
    • Litzelman, K.1    Witt, W.P.2    Gangnon, R.E.3    Nieto, F.J.4    Engelman, C.D.5    Mailick, M.R.6    Skinner, H.G.7
  • 81
    • 84901832871 scopus 로고    scopus 로고
    • Mitochondrial stress extends lifespan in C elegans through neuronal hormesis
    • Maglioni, S., Schiavi, A., Runci, A., Shaik, A., Ventura, N., Mitochondrial stress extends lifespan in C elegans through neuronal hormesis. Exp. Gerontol. 56 (2014), 89–98.
    • (2014) Exp. Gerontol. , vol.56 , pp. 89-98
    • Maglioni, S.1    Schiavi, A.2    Runci, A.3    Shaik, A.4    Ventura, N.5
  • 85
    • 0035027362 scopus 로고    scopus 로고
    • Repeated antenatal glucocorticoid treatment decreases hypothalamic corticotropin releasing hormone mRNA but not corticosteroid receptor mRNA expression in the fetal guinea-pig brain
    • McCabe, L., Marash, D., Li, A., Matthews, S.G., Repeated antenatal glucocorticoid treatment decreases hypothalamic corticotropin releasing hormone mRNA but not corticosteroid receptor mRNA expression in the fetal guinea-pig brain. J. Neuroendocrinol. 13 (2001), 425–431.
    • (2001) J. Neuroendocrinol. , vol.13 , pp. 425-431
    • McCabe, L.1    Marash, D.2    Li, A.3    Matthews, S.G.4
  • 89
    • 84866183226 scopus 로고    scopus 로고
    • Ageing as a risk factor for disease
    • Niccoli, T., Partridge, L., Ageing as a risk factor for disease. Curr. Biol. CB 22 (2012), R741–R752.
    • (2012) Curr. Biol. , vol.CB 22 , pp. R741-R752
    • Niccoli, T.1    Partridge, L.2
  • 92
    • 84903728455 scopus 로고    scopus 로고
    • Genome-wide DNA methylation in neonates exposed to maternal depression, anxiety, or SSRI medication during pregnancy
    • Non, A.L., Binder, A.M., Kubzansky, L.D., Michels, K.B., Genome-wide DNA methylation in neonates exposed to maternal depression, anxiety, or SSRI medication during pregnancy. Epigenetics 9 (2014), 964–972.
    • (2014) Epigenetics , vol.9 , pp. 964-972
    • Non, A.L.1    Binder, A.M.2    Kubzansky, L.D.3    Michels, K.B.4
  • 94
  • 99
    • 34247473478 scopus 로고    scopus 로고
    • The epigenetic basis of twin discordance in age-related diseases
    • Poulsen, P., Esteller, M., Vaag, A., Fraga, M.F., The epigenetic basis of twin discordance in age-related diseases. Pediatr. Res. 61 (2007), 38r–42r.
    • (2007) Pediatr. Res. , vol.61 , pp. 38r-42r
    • Poulsen, P.1    Esteller, M.2    Vaag, A.3    Fraga, M.F.4
  • 100
    • 85013207771 scopus 로고    scopus 로고
    • The State of Aging and Health in America 2013, Atlanta, GA.
    • Centers for Disease Control and Prevention, 2013. The State of Aging and Health in America 2013, Atlanta, GA.
    • (2013)
  • 101
    • 77955845440 scopus 로고    scopus 로고
    • The power of exercise: buffering the effect of chronic stress on telomere length
    • Puterman, E., Lin, J., Blackburn, E., O'Donovan, A., Adler, N., Epel, E., The power of exercise: buffering the effect of chronic stress on telomere length. PLoS One, 5, 2010, e10837.
    • (2010) PLoS One , vol.5 , pp. e10837
    • Puterman, E.1    Lin, J.2    Blackburn, E.3    O'Donovan, A.4    Adler, N.5    Epel, E.6
  • 103
    • 84877935103 scopus 로고    scopus 로고
    • Paternal stress exposure alters sperm microRNA content and reprograms offspring HPA stress axis regulation
    • Rodgers, A.B., Morgan, C.P., Bronson, S.L., Revello, S., Bale, T.L., Paternal stress exposure alters sperm microRNA content and reprograms offspring HPA stress axis regulation. J. Neurosci. 33 (2013), 9003–9012.
    • (2013) J. Neurosci. , vol.33 , pp. 9003-9012
    • Rodgers, A.B.1    Morgan, C.P.2    Bronson, S.L.3    Revello, S.4    Bale, T.L.5
  • 104
    • 0033608949 scopus 로고    scopus 로고
    • Impact of psychological factors on the pathogenesis of cardiovascular disease and implications for therapy
    • Rozanski, A., Blumenthal, J.A., Kaplan, J., Impact of psychological factors on the pathogenesis of cardiovascular disease and implications for therapy. Circulation 99 (1999), 2192–2217.
    • (1999) Circulation , vol.99 , pp. 2192-2217
    • Rozanski, A.1    Blumenthal, J.A.2    Kaplan, J.3
  • 106
    • 84942475138 scopus 로고    scopus 로고
    • Stress and the brain: individual variability and the inverted-U
    • Sapolsky, R.M., Stress and the brain: individual variability and the inverted-U. Nat. Neurosci. 18 (2015), 1344–1346.
    • (2015) Nat. Neurosci. , vol.18 , pp. 1344-1346
    • Sapolsky, R.M.1
  • 107
    • 84896853424 scopus 로고    scopus 로고
    • Associations between early life stress, self-reported traumatic experiences across the lifespan and leukocyte telomere length in elderly adults
    • Savolainen, K., Eriksson, J.G., Kananen, L., Kajantie, E., Pesonen, A.K., Heinonen, K., Raikkonen, K., Associations between early life stress, self-reported traumatic experiences across the lifespan and leukocyte telomere length in elderly adults. Biol. Psychol. 97 (2014), 35–42.
    • (2014) Biol. Psychol. , vol.97 , pp. 35-42
    • Savolainen, K.1    Eriksson, J.G.2    Kananen, L.3    Kajantie, E.4    Pesonen, A.K.5    Heinonen, K.6    Raikkonen, K.7
  • 109
    • 0028831128 scopus 로고
    • Characterization of mechanisms involved in transrepression of NF-kappa B by activated glucocorticoid receptors
    • Scheinman, R.I., Gualberto, A., Jewell, C.M., Cidlowski, J.A., Baldwin, A.S. Jr., Characterization of mechanisms involved in transrepression of NF-kappa B by activated glucocorticoid receptors. Mol. Cell. Biol. 15 (1995), 943–953.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 943-953
    • Scheinman, R.I.1    Gualberto, A.2    Jewell, C.M.3    Cidlowski, J.A.4    Baldwin, A.S.5
  • 110
    • 84899798561 scopus 로고    scopus 로고
    • Trans-generational effects of early life stress: the role of maternal behavior
    • Schmauss, C., Lee-McDermott, Z., Medina, L.R., Trans-generational effects of early life stress: the role of maternal behavior. Sci. Rep., 4, 2014, 4873.
    • (2014) Sci. Rep. , vol.4 , pp. 4873
    • Schmauss, C.1    Lee-McDermott, Z.2    Medina, L.R.3
  • 114
    • 84953205132 scopus 로고    scopus 로고
    • Economic hardship and biological weathering: the epigenetics of aging in a U.S. sample of black women
    • Simons, R.L., Lei, M.K., Beach, S.R., Philibert, R.A., Cutrona, C.E., Gibbons, F.X., Barr, A., Economic hardship and biological weathering: the epigenetics of aging in a U.S. sample of black women. Soc. Sci. Med. 150 (2016), 192–200.
    • (2016) Soc. Sci. Med. , vol.150 , pp. 192-200
    • Simons, R.L.1    Lei, M.K.2    Beach, S.R.3    Philibert, R.A.4    Cutrona, C.E.5    Gibbons, F.X.6    Barr, A.7
  • 115
    • 85013190969 scopus 로고    scopus 로고
    • National Population Projections, 2012-based Statistical Bulletin, Newport, UK
    • Office for National Statistics, 2012. National Population Projections, 2012-based Statistical Bulletin, Newport, UK.
    • (2012)
  • 116
    • 84856429606 scopus 로고    scopus 로고
    • Perceived psychological pressure at work, social class, and risk of stroke: a 30-year follow-up in Copenhagen male study
    • Suadicani, P., Andersen, L.L., Holtermann, A., Mortensen, O.S., Gyntelberg, F., Perceived psychological pressure at work, social class, and risk of stroke: a 30-year follow-up in Copenhagen male study. J. Occup. Environ. Med. 53 (2011), 1388–1395.
    • (2011) J. Occup. Environ. Med. , vol.53 , pp. 1388-1395
    • Suadicani, P.1    Andersen, L.L.2    Holtermann, A.3    Mortensen, O.S.4    Gyntelberg, F.5
  • 120
    • 84884784742 scopus 로고    scopus 로고
    • Age-associated epigenetic drift: implications, and a case of epigenetic thrift?
    • Teschendorff, A.E., West, J., Beck, S., Age-associated epigenetic drift: implications, and a case of epigenetic thrift?. Hum. Mol. Genet. 22 (2013), R7–r15.
    • (2013) Hum. Mol. Genet. , vol.22 , pp. R7-r15
    • Teschendorff, A.E.1    West, J.2    Beck, S.3
  • 121
    • 0035901508 scopus 로고    scopus 로고
    • Glucocorticoid-induced DNA demethylation and gene memory during development
    • Thomassin, H., Flavin, M., Espinas, M.L., Grange, T., Glucocorticoid-induced DNA demethylation and gene memory during development. EMBO J. 20 (2001), 1974–1983.
    • (2001) EMBO J. , vol.20 , pp. 1974-1983
    • Thomassin, H.1    Flavin, M.2    Espinas, M.L.3    Grange, T.4
  • 122
    • 84942551743 scopus 로고    scopus 로고
    • Epigenetic modulation of chronic anxiety and pain by histone deacetylation
    • Tran, L., Schulkin, J., Ligon, C.O., Greenwood-Van Meerveld, B., Epigenetic modulation of chronic anxiety and pain by histone deacetylation. Mol. Psychiatry 20 (2015), 1219–1231.
    • (2015) Mol. Psychiatry , vol.20 , pp. 1219-1231
    • Tran, L.1    Schulkin, J.2    Ligon, C.O.3    Greenwood-Van Meerveld, B.4
  • 123
    • 0036805791 scopus 로고    scopus 로고
    • Hypothalamic-pituitary-adrenal axis, neuroendocrine factors and stress
    • Tsigos, C., Chrousos, G.P., Hypothalamic-pituitary-adrenal axis, neuroendocrine factors and stress. J. Psychosom. Res. 53 (2002), 865–871.
    • (2002) J. Psychosom. Res. , vol.53 , pp. 865-871
    • Tsigos, C.1    Chrousos, G.P.2
  • 124
    • 65249131689 scopus 로고    scopus 로고
    • Severe psychological stress in elderly individuals: a proposed model of neurodegeneration and its implications
    • Tsolaki, M., Kounti, F., Karamavrou, S., Severe psychological stress in elderly individuals: a proposed model of neurodegeneration and its implications. Am. J. Alzheimers Dis. Other Demen. 24 (2009), 85–94.
    • (2009) Am. J. Alzheimers Dis. Other Demen. , vol.24 , pp. 85-94
    • Tsolaki, M.1    Kounti, F.2    Karamavrou, S.3
  • 127
    • 28044436691 scopus 로고    scopus 로고
    • Reversal of maternal programming of stress responses in adult offspring through methyl supplementation: altering epigenetic marking later in life
    • Weaver, I.C., Champagne, F.A., Brown, S.E., Dymov, S., Sharma, S., Meaney, M.J., Szyf, M., Reversal of maternal programming of stress responses in adult offspring through methyl supplementation: altering epigenetic marking later in life. J. Neurosci. 25 (2005), 11045–11054.
    • (2005) J. Neurosci. , vol.25 , pp. 11045-11054
    • Weaver, I.C.1    Champagne, F.A.2    Brown, S.E.3    Dymov, S.4    Sharma, S.5    Meaney, M.J.6    Szyf, M.7
  • 128
    • 33644763991 scopus 로고    scopus 로고
    • Maternal care effects on the hippocampal transcriptome and anxiety-mediated behaviors in the offspring that are reversible in adulthood
    • Weaver, I.C., Meaney, M.J., Szyf, M., Maternal care effects on the hippocampal transcriptome and anxiety-mediated behaviors in the offspring that are reversible in adulthood. Proc. Natl. Acad. Sci. U. S. A. 103 (2006), 3480–3485.
    • (2006) Proc. Natl. Acad. Sci. U. S. A. , vol.103 , pp. 3480-3485
    • Weaver, I.C.1    Meaney, M.J.2    Szyf, M.3
  • 131
    • 79959312161 scopus 로고    scopus 로고
    • Control of nuclear receptor function by local chromatin structure
    • Wiench, M., Miranda, T.B., Hager, G.L., Control of nuclear receptor function by local chromatin structure. FEBS J. 278 (2011), 2211–2230.
    • (2011) FEBS J. , vol.278 , pp. 2211-2230
    • Wiench, M.1    Miranda, T.B.2    Hager, G.L.3
  • 133
    • 14244262261 scopus 로고    scopus 로고
    • FK506-binding proteins 51 and 52 differentially regulate dynein interaction and nuclear translocation of the glucocorticoid receptor in mammalian cells
    • Wochnik, G.M., Ruegg, J., Abel, G.A., Schmidt, U., Holsboer, F., Rein, T., FK506-binding proteins 51 and 52 differentially regulate dynein interaction and nuclear translocation of the glucocorticoid receptor in mammalian cells. J. Biol. Chem. 280 (2005), 4609–4616.
    • (2005) J. Biol. Chem. , vol.280 , pp. 4609-4616
    • Wochnik, G.M.1    Ruegg, J.2    Abel, G.A.3    Schmidt, U.4    Holsboer, F.5    Rein, T.6
  • 135
    • 70349264308 scopus 로고    scopus 로고
    • Effects of cigarette smoking and restraint stress on human colon tumor growth in mice
    • Wong, H.P., Li, Z.J., Shin, V.Y., Tai, E.K., Wu, W.K., Yu, L., Cho, C.H., Effects of cigarette smoking and restraint stress on human colon tumor growth in mice. Digestion 80 (2009), 209–214.
    • (2009) Digestion , vol.80 , pp. 209-214
    • Wong, H.P.1    Li, Z.J.2    Shin, V.Y.3    Tai, E.K.4    Wu, W.K.5    Yu, L.6    Cho, C.H.7
  • 136
    • 84905377196 scopus 로고    scopus 로고
    • The role of H3K4me3 and H3K9/14ac in the induction by dexamethasone of Per1 and Sgk1, two glucococorticoid early response genes that mediate the effects of acute stress in mammals
    • Xydous, M., Prombona, A., Sourlingas, T.G., The role of H3K4me3 and H3K9/14ac in the induction by dexamethasone of Per1 and Sgk1, two glucococorticoid early response genes that mediate the effects of acute stress in mammals. Biochim. Biophys. Acta 1839 (2014), 866–872.
    • (2014) Biochim. Biophys. Acta , vol.1839 , pp. 866-872
    • Xydous, M.1    Prombona, A.2    Sourlingas, T.G.3
  • 137
    • 84859582204 scopus 로고    scopus 로고
    • Glucocorticoid-induced loss of DNA methylation in non-neuronal cells and potential involvement of DNMT1 in epigenetic regulation of Fkbp5
    • Yang, X., Ewald, E.R., Huo, Y., Tamashiro, K.L., Salvatori, R., Sawa, A., Wand, G.S., Lee, R.S., Glucocorticoid-induced loss of DNA methylation in non-neuronal cells and potential involvement of DNMT1 in epigenetic regulation of Fkbp5. Biochem. Biophys. Res. Commun. 420 (2012), 570–575.
    • (2012) Biochem. Biophys. Res. Commun. , vol.420 , pp. 570-575
    • Yang, X.1    Ewald, E.R.2    Huo, Y.3    Tamashiro, K.L.4    Salvatori, R.5    Sawa, A.6    Wand, G.S.7    Lee, R.S.8
  • 139
    • 84891633163 scopus 로고    scopus 로고
    • Gene-environment interactions at the FKBP5 locus: sensitive periods, mechanisms and pleiotropism
    • Zannas, A.S., Binder, E.B., Gene-environment interactions at the FKBP5 locus: sensitive periods, mechanisms and pleiotropism. Genes Brain Behav. 13:1 (2014), 25–37.
    • (2014) Genes Brain Behav. , vol.13 , Issue.1 , pp. 25-37
    • Zannas, A.S.1    Binder, E.B.2
  • 140
    • 84945538234 scopus 로고    scopus 로고
    • Glucocorticoid signaling drives epigenetic and transcription factors to induce key regulators of human parturition
    • Zannas, A.S., Chrousos, G.P., Glucocorticoid signaling drives epigenetic and transcription factors to induce key regulators of human parturition. Sci. Signal., 8, 2015, fs19.
    • (2015) Sci. Signal. , vol.8 , pp. fs19
    • Zannas, A.S.1    Chrousos, G.P.2
  • 141
    • 84895883596 scopus 로고    scopus 로고
    • Epigenetics and the regulation of stress vulnerability and resilience
    • Zannas, A.S., West, A.E., Epigenetics and the regulation of stress vulnerability and resilience. Neuroscience 264 (2014), 157–170.
    • (2014) Neuroscience , vol.264 , pp. 157-170
    • Zannas, A.S.1    West, A.E.2
  • 142
    • 84861868958 scopus 로고    scopus 로고
    • Stressful life events, perceived stress, and 12-month course of geriatric depression: direct effects and moderation by the 5-HTTLPR and COMT Val158Met polymorphisms
    • Zannas, A.S., McQuoid, D.R., Steffens, D.C., Chrousos, G.P., Taylor, W.D., Stressful life events, perceived stress, and 12-month course of geriatric depression: direct effects and moderation by the 5-HTTLPR and COMT Val158Met polymorphisms. Stress 15 (2012), 425–434.
    • (2012) Stress , vol.15 , pp. 425-434
    • Zannas, A.S.1    McQuoid, D.R.2    Steffens, D.C.3    Chrousos, G.P.4    Taylor, W.D.5
  • 144
    • 84949553248 scopus 로고    scopus 로고
    • Gene-stress-epigenetic regulation of FKBP5: clinical and translational implications
    • Zannas, A.S., Wiechmann, T., Gassen, N.C., Binder, E.B., Gene-stress-epigenetic regulation of FKBP5: clinical and translational implications. Neuropsychopharmacology 41:1 (2016), 261–274.
    • (2016) Neuropsychopharmacology , vol.41 , Issue.1 , pp. 261-274
    • Zannas, A.S.1    Wiechmann, T.2    Gassen, N.C.3    Binder, E.B.4
  • 145
    • 84969834369 scopus 로고    scopus 로고
    • Editorial perspective: psychological stress and epigenetic aging – what can we learn and how can we prevent?
    • Zannas, A.S., Editorial perspective: psychological stress and epigenetic aging – what can we learn and how can we prevent?. J. Child Psychol. Psychiatry 57:6 (2016), 674–675.
    • (2016) J. Child Psychol. Psychiatry , vol.57 , Issue.6 , pp. 674-675
    • Zannas, A.S.1
  • 146
    • 84874290059 scopus 로고    scopus 로고
    • Genome-wide DNA methylation patterns in discordant sib pairs with alcohol dependence
    • Zhao, R., Zhang, R., Li, W., Liao, Y., Tang, J., Miao, Q., Hao, W., Genome-wide DNA methylation patterns in discordant sib pairs with alcohol dependence. Asia-Pac. Psychiatry 5 (2013), 39–50.
    • (2013) Asia-Pac. Psychiatry , vol.5 , pp. 39-50
    • Zhao, R.1    Zhang, R.2    Li, W.3    Liao, Y.4    Tang, J.5    Miao, Q.6    Hao, W.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.