Early life stress triggers sustained changes in histone deacetylase expression and histone H4 modifications that alter responsiveness to adolescent antidepressant treatment

Neurobiology of Disease

Volumn 45, Issue 1, 2012, Pages 488-498

  Levine, Amir ^a   Worrell, Trent R ^a   Zimnisky, Ross ^a   Schmauss, Claudia ^a  

^a Och Spine at New York Presbyterian Hospitals   (United States)

Author keywords

Adolescent development; Early life stress; Frontal cortex; Histone deacetylases; Histone H4 acetylation; Mouse

Indexed keywords

FLUOXETINE; HISTONE DEACETYLASE; HISTONE DEACETYLASE 1; HISTONE DEACETYLASE 10; HISTONE DEACETYLASE 3; HISTONE DEACETYLASE 7; HISTONE DEACETYLASE 8; HISTONE DEACETYLASE INHIBITOR; HISTONE H4; HISTONE H4K12; MESSENGER RNA; THEOPHYLLINE; UNCLASSIFIED DRUG; VORINOSTAT;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DRUG EFFICACY; DRUG INHIBITION; EARLY LIFE STRESS; EMOTION; FEMALE; FOREBRAIN; GENE SEQUENCE; HISTONE ACETYLATION; HISTONE MODIFICATION; MALE; MATERNAL DEPRIVATION; MOUSE; NEOCORTEX; NONHUMAN; NUCLEOTIDE SEQUENCE; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; SINGLE DRUG DOSE; TREATMENT RESPONSE;

ANIMALS; ANTIDEPRESSIVE AGENTS; BEHAVIOR, ANIMAL; FLUOXETINE; HISTONE DEACETYLASES; HISTONES; MATERNAL DEPRIVATION; MICE; NEOCORTEX; PHENOTYPE; STRESS, PSYCHOLOGICAL;

EID: 81955164243     PISSN: 09699961     EISSN: 1095953X     Source Type: Journal    
DOI: 10.1016/j.nbd.2011.09.005     Document Type: Article

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