-
1
-
-
84950104119
-
Heart disease and stroke statistics-2016 update: a report from the American Heart Association
-
Mozaffarian D, Benjamin EJ, Go AS, Arnett DK, Blaha MJ, Cushman M, Das SR, de Ferranti S, Despres JP, Fullerton HJ, Howard VJ, Huffman MD, Isasi CR, Jimenez MC, Judd SE, Kissela BM, Lichtman JH, Lisabeth LD, Liu S, Mackey RH, Magid DJ, McGuire DK, Mohler ER 3rd, Moy CS, Muntner P, Mussolino ME, Nasir K, Neumar RW, Nichol G, Palaniappan L, Pandey DK, Reeves MJ, Rodriguez CJ, Rosamond W, Sorlie PD, Stein J, Towfighi A, Turan TN, Virani SS, Woo D, Yeh RW, Turner MB;
-
Mozaffarian D, Benjamin EJ, Go AS, Arnett DK, Blaha MJ, Cushman M, Das SR, de Ferranti S, Despres JP, Fullerton HJ, Howard VJ, Huffman MD, Isasi CR, Jimenez MC, Judd SE, Kissela BM, Lichtman JH, Lisabeth LD, Liu S, Mackey RH, Magid DJ, McGuire DK, Mohler ER 3rd, Moy CS, Muntner P, Mussolino ME, Nasir K, Neumar RW, Nichol G, Palaniappan L, Pandey DK, Reeves MJ, Rodriguez CJ, Rosamond W, Sorlie PD, Stein J, Towfighi A, Turan TN, Virani SS, Woo D, Yeh RW, Turner MB; American Heart Association Statistics C, Stroke Statistics S (2016) Heart disease and stroke statistics-2016 update: a report from the American Heart Association. Circulation 133:e38–e360
-
(2016)
Circulation
, vol.133
, pp. e38-e360
-
-
-
2
-
-
84920703518
-
Causes of Death C
-
Mortality GBD, Causes of Death C (2015) Global, regional, and national age-sex specific all-cause and cause-specific mortality for 240 causes of death, 1990–2013: a systematic analysis for the Global Burden of Disease Study 2013. Lancet 385:117–171
-
(2015)
Global, regional, and national age-sex specific all-cause and cause-specific mortality for 240 causes of death, 1990–2013: a systematic analysis for the Global Burden of Disease Study 2013. Lancet
, vol.385
, pp. 117-171
-
-
Mortality, G.B.D.1
-
3
-
-
33646693410
-
Contemporary definitions and classification of the cardiomyopathies: an American Heart Association Scientific Statement from the Council on Clinical Cardiology, Heart Failure and Transplantation Committee; Quality of Care and Outcomes Research and Functional Genomics and Translational Biology Interdisciplinary Working Groups; and Council on Epidemiology and Prevention
-
Maron BJ, Towbin JA, Thiene G, Antzelevitch C, Corrado D, Arnett D, Moss AJ, Seidman CE, Young JB, American Heart A, Council on Clinical Cardiology HF, Transplantation C, Quality of C, Outcomes R, Functional G
-
Maron BJ, Towbin JA, Thiene G, Antzelevitch C, Corrado D, Arnett D, Moss AJ, Seidman CE, Young JB, American Heart A, Council on Clinical Cardiology HF, Transplantation C, Quality of C, Outcomes R, Functional G, Translational Biology Interdisciplinary Working G, Council on E, Prevention (2006) Contemporary definitions and classification of the cardiomyopathies: an American Heart Association Scientific Statement from the Council on Clinical Cardiology, Heart Failure and Transplantation Committee; Quality of Care and Outcomes Research and Functional Genomics and Translational Biology Interdisciplinary Working Groups; and Council on Epidemiology and Prevention. Circulation 113:1807–1816
-
(2006)
Circulation
, vol.113
, pp. 1807-1816
-
-
-
4
-
-
84872551624
-
Hypertrophic cardiomyopathy
-
PID: 22874472
-
Maron BJ, Maron MS (2013) Hypertrophic cardiomyopathy. Lancet 381:242–255
-
(2013)
Lancet
, vol.381
, pp. 242-255
-
-
Maron, B.J.1
Maron, M.S.2
-
6
-
-
74149091717
-
Activation of cardiac hypertrophic signaling pathways in a transgenic mouse with the human PRKAG2 Thr400Asn mutation
-
COI: 1:CAS:528:DC%2BC3cXntVWktg%3D%3D, PID: 20005292
-
Banerjee SK, McGaffin KR, Huang XN, Ahmad F (2010) Activation of cardiac hypertrophic signaling pathways in a transgenic mouse with the human PRKAG2 Thr400Asn mutation. Biochim Biophys Acta 1802:284–291
-
(2010)
Biochim Biophys Acta
, vol.1802
, pp. 284-291
-
-
Banerjee, S.K.1
McGaffin, K.R.2
Huang, X.N.3
Ahmad, F.4
-
7
-
-
84898599740
-
Metabolic crosstalk between the heart and liver impacts familial hypertrophic cardiomyopathy
-
COI: 1:CAS:528:DC%2BC2cXltlalu7w%3D, PID: 24567073
-
Magida JA, Leinwand LA (2014) Metabolic crosstalk between the heart and liver impacts familial hypertrophic cardiomyopathy. EMBO Mol Med 6:482–495
-
(2014)
EMBO Mol Med
, vol.6
, pp. 482-495
-
-
Magida, J.A.1
Leinwand, L.A.2
-
8
-
-
19944369735
-
Adiponectin-mediated modulation of hypertrophic signals in the heart
-
COI: 1:CAS:528:DC%2BD2cXhtVCisbfL, PID: 15558058
-
Shibata R, Ouchi N, Ito M, Kihara S, Shiojima I, Pimentel DR, Kumada M, Sato K, Schiekofer S, Ohashi K, Funahashi T, Colucci WS, Walsh K (2004) Adiponectin-mediated modulation of hypertrophic signals in the heart. Nat Med 10:1384–1389
-
(2004)
Nat Med
, vol.10
, pp. 1384-1389
-
-
Shibata, R.1
Ouchi, N.2
Ito, M.3
Kihara, S.4
Shiojima, I.5
Pimentel, D.R.6
Kumada, M.7
Sato, K.8
Schiekofer, S.9
Ohashi, K.10
Funahashi, T.11
Colucci, W.S.12
Walsh, K.13
-
9
-
-
84883825935
-
C1q/tumor necrosis factor-related protein-9, a novel adipocyte-derived cytokine, attenuates adverse remodeling in the ischemic mouse heart via protein kinase A activation
-
COI: 1:CAS:528:DC%2BC3sXhsVens7vJ, PID: 24030394
-
Sun Y, Yi W, Yuan Y, Lau WB, Yi D, Wang X, Wang Y, Su H, Wang X, Gao E, Koch WJ, Ma XL (2013) C1q/tumor necrosis factor-related protein-9, a novel adipocyte-derived cytokine, attenuates adverse remodeling in the ischemic mouse heart via protein kinase A activation. Circulation 128:S113–S120
-
(2013)
Circulation
, vol.128
, pp. S113-S120
-
-
Sun, Y.1
Yi, W.2
Yuan, Y.3
Lau, W.B.4
Yi, D.5
Wang, X.6
Wang, Y.7
Su, H.8
Wang, X.9
Gao, E.10
Koch, W.J.11
Ma, X.L.12
-
10
-
-
84863210727
-
C1q/tumor necrosis factor-related protein-3, a newly identified adipokine, is a novel antiapoptotic, proangiogenic, and cardioprotective molecule in the ischemic mouse heart
-
COI: 1:CAS:528:DC%2BC38XptF2ms7Y%3D, PID: 22653084
-
Yi W, Sun Y, Yuan Y, Lau WB, Zheng Q, Wang X, Wang Y, Shang X, Gao E, Koch WJ, Ma XL (2012) C1q/tumor necrosis factor-related protein-3, a newly identified adipokine, is a novel antiapoptotic, proangiogenic, and cardioprotective molecule in the ischemic mouse heart. Circulation 125:3159–3169
-
(2012)
Circulation
, vol.125
, pp. 3159-3169
-
-
Yi, W.1
Sun, Y.2
Yuan, Y.3
Lau, W.B.4
Zheng, Q.5
Wang, X.6
Wang, Y.7
Shang, X.8
Gao, E.9
Koch, W.J.10
Ma, X.L.11
-
11
-
-
80054916958
-
C1q/TNF-related proteins, a family of novel adipokines, induce vascular relaxation through the adiponectin receptor-1/AMPK/eNOS/nitric oxide signaling pathway
-
COI: 1:CAS:528:DC%2BC3MXhtlChsr7N, PID: 21836066
-
Zheng Q, Yuan Y, Yi W, Lau WB, Wang Y, Wang X, Sun Y, Lopez BL, Christopher TA, Peterson JM, Wong GW, Yu S, Yi D, Ma XL (2011) C1q/TNF-related proteins, a family of novel adipokines, induce vascular relaxation through the adiponectin receptor-1/AMPK/eNOS/nitric oxide signaling pathway. Arterioscler Thromb Vasc Biol 31:2616–2623
-
(2011)
Arterioscler Thromb Vasc Biol
, vol.31
, pp. 2616-2623
-
-
Zheng, Q.1
Yuan, Y.2
Yi, W.3
Lau, W.B.4
Wang, Y.5
Wang, X.6
Sun, Y.7
Lopez, B.L.8
Christopher, T.A.9
Peterson, J.M.10
Wong, G.W.11
Yu, S.12
Yi, D.13
Ma, X.L.14
-
12
-
-
84957057763
-
Melatonin reverses flow shear stress-induced injury in bone marrow mesenchymal stem cells via activation of AMP-activated protein kinase signaling
-
COI: 1:CAS:528:DC%2BC28XhvFSnsrc%3D, PID: 26707568
-
Yang Y, Fan C, Deng C, Zhao L, Hu W, Di S, Ma Z, Zhang Y, Qin Z, Jin Z, Yan X, Jiang S, Sun Y, Yi W (2016) Melatonin reverses flow shear stress-induced injury in bone marrow mesenchymal stem cells via activation of AMP-activated protein kinase signaling. J Pineal Res 60:228–241
-
(2016)
J Pineal Res
, vol.60
, pp. 228-241
-
-
Yang, Y.1
Fan, C.2
Deng, C.3
Zhao, L.4
Hu, W.5
Di, S.6
Ma, Z.7
Zhang, Y.8
Qin, Z.9
Jin, Z.10
Yan, X.11
Jiang, S.12
Sun, Y.13
Yi, W.14
-
13
-
-
33748323383
-
Regulation of cardiac hypertrophy by intracellular signalling pathways
-
COI: 1:CAS:528:DC%2BD28Xot1Cqu78%3D, PID: 16936699
-
Heineke J, Molkentin JD (2006) Regulation of cardiac hypertrophy by intracellular signalling pathways. Nat Rev Mol Cell Biol 7:589–600
-
(2006)
Nat Rev Mol Cell Biol
, vol.7
, pp. 589-600
-
-
Heineke, J.1
Molkentin, J.D.2
-
14
-
-
84940448592
-
Left ventricular non-compaction cardiomyopathy
-
PID: 25865865
-
Towbin JA, Lorts A, Jefferies JL (2015) Left ventricular non-compaction cardiomyopathy. Lancet 386:813–825
-
(2015)
Lancet
, vol.386
, pp. 813-825
-
-
Towbin, J.A.1
Lorts, A.2
Jefferies, J.L.3
-
15
-
-
65249183838
-
Resveratrol prevents the prohypertrophic effects of oxidative stress on LKB1
-
COI: 1:CAS:528:DC%2BD1MXjsVKrtLs%3D, PID: 19289642
-
Dolinsky VW, Chan AY, Robillard Frayne I, Light PE, Des Rosiers C, Dyck JR (2009) Resveratrol prevents the prohypertrophic effects of oxidative stress on LKB1. Circulation 119:1643–1652
-
(2009)
Circulation
, vol.119
, pp. 1643-1652
-
-
Dolinsky, V.W.1
Chan, A.Y.2
Robillard Frayne, I.3
Light, P.E.4
Des Rosiers, C.5
Dyck, J.R.6
-
16
-
-
84907545906
-
AMPK: positive and negative regulation, and its role in whole-body energy homeostasis
-
COI: 1:CAS:528:DC%2BC2cXhsFyitLnL, PID: 25259783
-
Hardie DG (2015) AMPK: positive and negative regulation, and its role in whole-body energy homeostasis. Curr Opin Cell Biol 33:1–7
-
(2015)
Curr Opin Cell Biol
, vol.33
, pp. 1-7
-
-
Hardie, D.G.1
-
17
-
-
34648828532
-
AMP-activated/SNF1 protein kinases: conserved guardians of cellular energy
-
COI: 1:CAS:528:DC%2BD2sXhtVKmt7vP, PID: 17712357
-
Hardie DG (2007) AMP-activated/SNF1 protein kinases: conserved guardians of cellular energy. Nat Rev Mol Cell Biol 8:774–785
-
(2007)
Nat Rev Mol Cell Biol
, vol.8
, pp. 774-785
-
-
Hardie, D.G.1
-
18
-
-
84878971103
-
Conserved regulatory elements in AMPK
-
COI: 1:CAS:528:DC%2BC3sXptlGkurc%3D, PID: 23765502
-
Chen L, Xin FJ, Wang J, Hu J, Zhang YY, Wan S, Cao LS, Lu C, Li P, Yan SF, Neumann D, Schlattner U, Xia B, Wang ZX, Wu JW (2013) Conserved regulatory elements in AMPK. Nature 498:E8–10
-
(2013)
Nature
, vol.498
, pp. E8-E10
-
-
Chen, L.1
Xin, F.J.2
Wang, J.3
Hu, J.4
Zhang, Y.Y.5
Wan, S.6
Cao, L.S.7
Lu, C.8
Li, P.9
Yan, S.F.10
Neumann, D.11
Schlattner, U.12
Xia, B.13
Wang, Z.X.14
Wu, J.W.15
-
19
-
-
84930578220
-
Beyond energy homeostasis: the expanding role of AMP-activated protein kinase in regulating metabolism
-
COI: 1:CAS:528:DC%2BC2MXovV2qtLs%3D, PID: 26039446
-
Carling D, Viollet B (2015) Beyond energy homeostasis: the expanding role of AMP-activated protein kinase in regulating metabolism. Cell Metab 21:799–804
-
(2015)
Cell Metab
, vol.21
, pp. 799-804
-
-
Carling, D.1
Viollet, B.2
-
20
-
-
84865846785
-
AMP-activated protein kinase regulation and biological actions in the heart
-
COI: 1:CAS:528:DC%2BC38Xht1OgtL7L, PID: 22935535
-
Zaha VG, Young LH (2012) AMP-activated protein kinase regulation and biological actions in the heart. Circ Res 111:800–814
-
(2012)
Circ Res
, vol.111
, pp. 800-814
-
-
Zaha, V.G.1
Young, L.H.2
-
21
-
-
84897534723
-
Phosphorylation by Akt within the ST loop of AMPK-alpha1 down-regulates its activation in tumour cells
-
COI: 1:CAS:528:DC%2BC2cXltFOqsLk%3D, PID: 24467442
-
Hawley SA, Ross FA, Gowans GJ, Tibarewal P, Leslie NR, Hardie DG (2014) Phosphorylation by Akt within the ST loop of AMPK-alpha1 down-regulates its activation in tumour cells. Biochem J 459:275–287
-
(2014)
Biochem J
, vol.459
, pp. 275-287
-
-
Hawley, S.A.1
Ross, F.A.2
Gowans, G.J.3
Tibarewal, P.4
Leslie, N.R.5
Hardie, D.G.6
-
22
-
-
67649484365
-
Structural insight into the autoinhibition mechanism of AMP-activated protein kinase
-
COI: 1:CAS:528:DC%2BD1MXmsVGhsbw%3D, PID: 19474788
-
Chen L, Jiao ZH, Zheng LS, Zhang YY, Xie ST, Wang ZX, Wu JW (2009) Structural insight into the autoinhibition mechanism of AMP-activated protein kinase. Nature 459:1146–1149
-
(2009)
Nature
, vol.459
, pp. 1146-1149
-
-
Chen, L.1
Jiao, Z.H.2
Zheng, L.S.3
Zhang, Y.Y.4
Xie, S.T.5
Wang, Z.X.6
Wu, J.W.7
-
23
-
-
39549092137
-
AMP-activated protein kinase conducts the ischemic stress response orchestra
-
PID: 18268160
-
Young LH (2008) AMP-activated protein kinase conducts the ischemic stress response orchestra. Circulation 117:832–840
-
(2008)
Circulation
, vol.117
, pp. 832-840
-
-
Young, L.H.1
-
24
-
-
0026668252
-
Sustained protection by acadesine against ischemia- and reperfusion-induced injury. Studies in the transplanted rat heart
-
COI: 1:CAS:528:DyaK38XmtVCrtro%3D, PID: 1638724
-
Galinanes M, Bullough D, Mullane KM, Hearse DJ (1992) Sustained protection by acadesine against ischemia- and reperfusion-induced injury. Studies in the transplanted rat heart. Circulation 86:589–597
-
(1992)
Circulation
, vol.86
, pp. 589-597
-
-
Galinanes, M.1
Bullough, D.2
Mullane, K.M.3
Hearse, D.J.4
-
25
-
-
79953830840
-
AMP-activated protein kinase regulates neuronal polarization by interfering with PI 3-kinase localization
-
COI: 1:CAS:528:DC%2BC3MXksV2qtbo%3D, PID: 21436401
-
Amato S, Liu X, Zheng B, Cantley L, Rakic P, Man HY (2011) AMP-activated protein kinase regulates neuronal polarization by interfering with PI 3-kinase localization. Science 332:247–251
-
(2011)
Science
, vol.332
, pp. 247-251
-
-
Amato, S.1
Liu, X.2
Zheng, B.3
Cantley, L.4
Rakic, P.5
Man, H.Y.6
-
26
-
-
84946899816
-
AMP-activated protein kinase (AMPK) control of mTORC1 Is p53- and TSC2-independent in pemetrexed-treated carcinoma cells
-
COI: 1:CAS:528:DC%2BC2MXhvVeqt73E, PID: 26391395
-
Agarwal S, Bell CM, Rothbart SB, Moran RG (2015) AMP-activated protein kinase (AMPK) control of mTORC1 Is p53- and TSC2-independent in pemetrexed-treated carcinoma cells. J Biol Chem 290:27473–27486
-
(2015)
J Biol Chem
, vol.290
, pp. 27473-27486
-
-
Agarwal, S.1
Bell, C.M.2
Rothbart, S.B.3
Moran, R.G.4
-
27
-
-
66349105917
-
Metformin prevents progression of heart failure in dogs: role of AMP-activated protein kinase
-
COI: 1:CAS:528:DC%2BD1MXmtVKntrg%3D, PID: 19414638
-
Sasaki H, Asanuma H, Fujita M, Takahama H, Wakeno M, Ito S, Ogai A, Asakura M, Kim J, Minamino T, Takashima S, Sanada S, Sugimachi M, Komamura K, Mochizuki N, Kitakaze M (2009) Metformin prevents progression of heart failure in dogs: role of AMP-activated protein kinase. Circulation 119:2568–2577
-
(2009)
Circulation
, vol.119
, pp. 2568-2577
-
-
Sasaki, H.1
Asanuma, H.2
Fujita, M.3
Takahama, H.4
Wakeno, M.5
Ito, S.6
Ogai, A.7
Asakura, M.8
Kim, J.9
Minamino, T.10
Takashima, S.11
Sanada, S.12
Sugimachi, M.13
Komamura, K.14
Mochizuki, N.15
Kitakaze, M.16
-
28
-
-
0031974516
-
Peutz–Jeghers syndrome is caused by mutations in a novel serine threonine kinase
-
COI: 1:CAS:528:DyaK1cXivFelsw%3D%3D, PID: 9425897
-
Jenne DE, Reimann H, Nezu J, Friedel W, Loff S, Jeschke R, Muller O, Back W, Zimmer M (1998) Peutz–Jeghers syndrome is caused by mutations in a novel serine threonine kinase. Nat Genet 18:38–43
-
(1998)
Nat Genet
, vol.18
, pp. 38-43
-
-
Jenne, D.E.1
Reimann, H.2
Nezu, J.3
Friedel, W.4
Loff, S.5
Jeschke, R.6
Muller, O.7
Back, W.8
Zimmer, M.9
-
29
-
-
79954488111
-
Aldehyde dehydrogenase 2 (ALDH2) rescues myocardial ischaemia/reperfusion injury: role of autophagy paradox and toxic aldehyde
-
COI: 1:CAS:528:DC%2BC3MXkvFaksb8%3D, PID: 20705694
-
Ma H, Guo R, Yu L, Zhang Y, Ren J (2011) Aldehyde dehydrogenase 2 (ALDH2) rescues myocardial ischaemia/reperfusion injury: role of autophagy paradox and toxic aldehyde. Eur Heart J 32:1025–1038
-
(2011)
Eur Heart J
, vol.32
, pp. 1025-1038
-
-
Ma, H.1
Guo, R.2
Yu, L.3
Zhang, Y.4
Ren, J.5
-
30
-
-
84922104763
-
MicroRNA-451 exacerbates lipotoxicity in cardiac myocytes and high-fat diet-induced cardiac hypertrophy in mice through suppression of the LKB1/AMPK pathway
-
COI: 1:CAS:528:DC%2BC2MXpslKjug%3D%3D, PID: 25362209
-
Kuwabara Y, Horie T, Baba O, Watanabe S, Nishiga M, Usami S, Izuhara M, Nakao T, Nishino T, Otsu K, Kita T, Kimura T, Ono K (2015) MicroRNA-451 exacerbates lipotoxicity in cardiac myocytes and high-fat diet-induced cardiac hypertrophy in mice through suppression of the LKB1/AMPK pathway. Circ Res 116:279–288
-
(2015)
Circ Res
, vol.116
, pp. 279-288
-
-
Kuwabara, Y.1
Horie, T.2
Baba, O.3
Watanabe, S.4
Nishiga, M.5
Usami, S.6
Izuhara, M.7
Nakao, T.8
Nishino, T.9
Otsu, K.10
Kita, T.11
Kimura, T.12
Ono, K.13
-
31
-
-
84901329684
-
Small molecule drug A-769662 and AMP synergistically activate naive AMPK independent of upstream kinase signaling
-
COI: 1:CAS:528:DC%2BC2cXmsVCjsLY%3D, PID: 24746562
-
Scott JW, Ling N, Issa SM, Dite TA, O’Brien MT, Chen ZP, Galic S, Langendorf CG, Steinberg GR, Kemp BE, Oakhill JS (2014) Small molecule drug A-769662 and AMP synergistically activate naive AMPK independent of upstream kinase signaling. Chem Biol 21:619–627
-
(2014)
Chem Biol
, vol.21
, pp. 619-627
-
-
Scott, J.W.1
Ling, N.2
Issa, S.M.3
Dite, T.A.4
O’Brien, M.T.5
Chen, Z.P.6
Galic, S.7
Langendorf, C.G.8
Steinberg, G.R.9
Kemp, B.E.10
Oakhill, J.S.11
-
32
-
-
57749083482
-
Metabolic switch and hypertrophy of cardiomyocytes following treatment with angiotensin II are prevented by AMP-activated protein kinase
-
COI: 1:CAS:528:DC%2BD1cXhtlOjtLrP, PID: 18790741
-
Stuck BJ, Lenski M, Bohm M, Laufs U (2008) Metabolic switch and hypertrophy of cardiomyocytes following treatment with angiotensin II are prevented by AMP-activated protein kinase. J Biol Chem 283:32562–32569
-
(2008)
J Biol Chem
, vol.283
, pp. 32562-32569
-
-
Stuck, B.J.1
Lenski, M.2
Bohm, M.3
Laufs, U.4
-
33
-
-
84874641762
-
AMPK attenuates microtubule proliferation in cardiac hypertrophy
-
COI: 1:CAS:528:DC%2BC3sXlvVKgsrw%3D, PID: 23316058
-
Fassett JT, Hu X, Xu X, Lu Z, Zhang P, Chen Y, Bache RJ (2013) AMPK attenuates microtubule proliferation in cardiac hypertrophy. Am J Physiol Heart Circ Physiol 304:H749–H758
-
(2013)
Am J Physiol Heart Circ Physiol
, vol.304
, pp. H749-H758
-
-
Fassett, J.T.1
Hu, X.2
Xu, X.3
Lu, Z.4
Zhang, P.5
Chen, Y.6
Bache, R.J.7
-
34
-
-
53049091294
-
Resveratrol inhibits cardiac hypertrophy via AMP-activated protein kinase and Akt
-
COI: 1:CAS:528:DC%2BD1cXhtVWktrjI, PID: 18562309
-
Chan AY, Dolinsky VW, Soltys CL, Viollet B, Baksh S, Light PE, Dyck JR (2008) Resveratrol inhibits cardiac hypertrophy via AMP-activated protein kinase and Akt. J Biol Chem 283:24194–24201
-
(2008)
J Biol Chem
, vol.283
, pp. 24194-24201
-
-
Chan, A.Y.1
Dolinsky, V.W.2
Soltys, C.L.3
Viollet, B.4
Baksh, S.5
Light, P.E.6
Dyck, J.R.7
-
35
-
-
77449120223
-
Exogenous NAD blocks cardiac hypertrophic response via activation of the SIRT3-LKB1-AMP-activated kinase pathway
-
COI: 1:CAS:528:DC%2BC3cXovVemug%3D%3D, PID: 19940131
-
Pillai VB, Sundaresan NR, Kim G, Gupta M, Rajamohan SB, Pillai JB, Samant S, Ravindra PV, Isbatan A, Gupta MP (2010) Exogenous NAD blocks cardiac hypertrophic response via activation of the SIRT3-LKB1-AMP-activated kinase pathway. J Biol Chem 285:3133–3144
-
(2010)
J Biol Chem
, vol.285
, pp. 3133-3144
-
-
Pillai, V.B.1
Sundaresan, N.R.2
Kim, G.3
Gupta, M.4
Rajamohan, S.B.5
Pillai, J.B.6
Samant, S.7
Ravindra, P.V.8
Isbatan, A.9
Gupta, M.P.10
-
36
-
-
33847729893
-
Expression of an active LKB1 complex in cardiac myocytes results in decreased protein synthesis associated with phenylephrine-induced hypertrophy
-
COI: 1:CAS:528:DC%2BD2sXjsVylsbo%3D, PID: 17098823
-
Noga AA, Soltys CL, Barr AJ, Kovacic S, Lopaschuk GD, Dyck JR (2007) Expression of an active LKB1 complex in cardiac myocytes results in decreased protein synthesis associated with phenylephrine-induced hypertrophy. Am J Physiol Heart Circ Physiol 292:H1460–H1469
-
(2007)
Am J Physiol Heart Circ Physiol
, vol.292
, pp. H1460-H1469
-
-
Noga, A.A.1
Soltys, C.L.2
Barr, A.J.3
Kovacic, S.4
Lopaschuk, G.D.5
Dyck, J.R.6
-
37
-
-
84905861495
-
Retinoid X receptor agonists inhibit hypertension-induced myocardial hypertrophy by modulating LKB1/AMPK/p70S6K signaling pathway
-
PID: 24603314
-
Zhu J, Ning RB, Lin XY, Chai DJ, Xu CS, Xie H, Zeng JZ, Lin JX (2014) Retinoid X receptor agonists inhibit hypertension-induced myocardial hypertrophy by modulating LKB1/AMPK/p70S6K signaling pathway. Am J Hypertens 27:1112–1124
-
(2014)
Am J Hypertens
, vol.27
, pp. 1112-1124
-
-
Zhu, J.1
Ning, R.B.2
Lin, X.Y.3
Chai, D.J.4
Xu, C.S.5
Xie, H.6
Zeng, J.Z.7
Lin, J.X.8
-
38
-
-
79956336867
-
Resistin promotes cardiac hypertrophy via the AMP-activated protein kinase/mammalian target of rapamycin (AMPK/mTOR) and c-Jun N-terminal kinase/insulin receptor substrate 1 (JNK/IRS1) pathways
-
COI: 1:CAS:528:DC%2BC3MXmtlGlsbo%3D, PID: 21478152
-
Kang S, Chemaly ER, Hajjar RJ, Lebeche D (2011) Resistin promotes cardiac hypertrophy via the AMP-activated protein kinase/mammalian target of rapamycin (AMPK/mTOR) and c-Jun N-terminal kinase/insulin receptor substrate 1 (JNK/IRS1) pathways. J Biol Chem 286:18465–18473
-
(2011)
J Biol Chem
, vol.286
, pp. 18465-18473
-
-
Kang, S.1
Chemaly, E.R.2
Hajjar, R.J.3
Lebeche, D.4
-
39
-
-
79960046907
-
Metformin attenuates pressure overload-induced cardiac hypertrophy via AMPK activation
-
COI: 1:CAS:528:DC%2BC3MXotlequrc%3D, PID: 21552292
-
Fu YN, Xiao H, Ma XW, Jiang SY, Xu M, Zhang YY (2011) Metformin attenuates pressure overload-induced cardiac hypertrophy via AMPK activation. Acta Pharmacol Sin 32:879–887
-
(2011)
Acta Pharmacol Sin
, vol.32
, pp. 879-887
-
-
Fu, Y.N.1
Xiao, H.2
Ma, X.W.3
Jiang, S.Y.4
Xu, M.5
Zhang, Y.Y.6
-
40
-
-
84925016718
-
The lipid peroxidation product 4-hydroxy-trans-2-nonenal causes protein synthesis in cardiac myocytes via activated mTORC1-p70S6K-RPS6 signaling
-
COI: 1:CAS:528:DC%2BC2MXjtFSitLk%3D, PID: 25617592
-
Calamaras TD, Lee C, Lan F, Ido Y, Siwik DA, Colucci WS (2015) The lipid peroxidation product 4-hydroxy-trans-2-nonenal causes protein synthesis in cardiac myocytes via activated mTORC1-p70S6K-RPS6 signaling. Free Radic Biol Med 82:137–146
-
(2015)
Free Radic Biol Med
, vol.82
, pp. 137-146
-
-
Calamaras, T.D.1
Lee, C.2
Lan, F.3
Ido, Y.4
Siwik, D.A.5
Colucci, W.S.6
-
41
-
-
84904047161
-
Myostatin regulates energy homeostasis in the heart and prevents heart failure
-
COI: 1:CAS:528:DC%2BC2cXhtVOgtLzL, PID: 24807786
-
Biesemann N, Mendler L, Wietelmann A, Hermann S, Schafers M, Kruger M, Boettger T, Borchardt T, Braun T (2014) Myostatin regulates energy homeostasis in the heart and prevents heart failure. Circ Res 115:296–310
-
(2014)
Circ Res
, vol.115
, pp. 296-310
-
-
Biesemann, N.1
Mendler, L.2
Wietelmann, A.3
Hermann, S.4
Schafers, M.5
Kruger, M.6
Boettger, T.7
Borchardt, T.8
Braun, T.9
-
42
-
-
19944434362
-
Glycogen storage diseases presenting as hypertrophic cardiomyopathy
-
COI: 1:CAS:528:DC%2BD2MXnvVKmuw%3D%3D, PID: 15673802
-
Arad M, Maron BJ, Gorham JM, Johnson WH Jr, Saul JP, Perez-Atayde AR, Spirito P, Wright GB, Kanter RJ, Seidman CE, Seidman JG (2005) Glycogen storage diseases presenting as hypertrophic cardiomyopathy. N Engl J Med 352:362–372
-
(2005)
N Engl J Med
, vol.352
, pp. 362-372
-
-
Arad, M.1
Maron, B.J.2
Gorham, J.M.3
Johnson, W.H.4
Saul, J.P.5
Perez-Atayde, A.R.6
Spirito, P.7
Wright, G.B.8
Kanter, R.J.9
Seidman, C.E.10
Seidman, J.G.11
-
43
-
-
0036167225
-
Constitutively active AMP kinase mutations cause glycogen storage disease mimicking hypertrophic cardiomyopathy
-
COI: 1:CAS:528:DC%2BD38XhtV2isLY%3D, PID: 11827995
-
Arad M, Benson DW, Perez-Atayde AR, McKenna WJ, Sparks EA, Kanter RJ, McGarry K, Seidman JG, Seidman CE (2002) Constitutively active AMP kinase mutations cause glycogen storage disease mimicking hypertrophic cardiomyopathy. J Clin Invest 109:357–362
-
(2002)
J Clin Invest
, vol.109
, pp. 357-362
-
-
Arad, M.1
Benson, D.W.2
Perez-Atayde, A.R.3
McKenna, W.J.4
Sparks, E.A.5
Kanter, R.J.6
McGarry, K.7
Seidman, J.G.8
Seidman, C.E.9
-
44
-
-
33644874700
-
Increased alpha2 subunit-associated AMPK activity and PRKAG2 cardiomyopathy
-
COI: 1:CAS:528:DC%2BD2MXhtF2rtbfO, PID: 16275868
-
Ahmad F, Arad M, Musi N, He H, Wolf C, Branco D, Perez-Atayde AR, Stapleton D, Bali D, Xing Y, Tian R, Goodyear LJ, Berul CI, Ingwall JS, Seidman CE, Seidman JG (2005) Increased alpha2 subunit-associated AMPK activity and PRKAG2 cardiomyopathy. Circulation 112:3140–3148
-
(2005)
Circulation
, vol.112
, pp. 3140-3148
-
-
Ahmad, F.1
Arad, M.2
Musi, N.3
He, H.4
Wolf, C.5
Branco, D.6
Perez-Atayde, A.R.7
Stapleton, D.8
Bali, D.9
Xing, Y.10
Tian, R.11
Goodyear, L.J.12
Berul, C.I.13
Ingwall, J.S.14
Seidman, C.E.15
Seidman, J.G.16
-
45
-
-
84897092493
-
Mutation in the gamma2-subunit of AMP-activated protein kinase stimulates cardiomyocyte proliferation and hypertrophy independent of glycogen storage
-
COI: 1:CAS:528:DC%2BC2cXktF2lur0%3D, PID: 24503893
-
Kim M, Hunter RW, Garcia-Menendez L, Gong G, Yang YY, Kolwicz SC Jr, Xu J, Sakamoto K, Wang W, Tian R (2014) Mutation in the gamma2-subunit of AMP-activated protein kinase stimulates cardiomyocyte proliferation and hypertrophy independent of glycogen storage. Circ Res 114:966–975
-
(2014)
Circ Res
, vol.114
, pp. 966-975
-
-
Kim, M.1
Hunter, R.W.2
Garcia-Menendez, L.3
Gong, G.4
Yang, Y.Y.5
Kolwicz, S.C.6
Xu, J.7
Sakamoto, K.8
Wang, W.9
Tian, R.10
-
46
-
-
84866426382
-
Apelin prevents cardiac fibroblast activation and collagen production through inhibition of sphingosine kinase 1
-
COI: 1:CAS:528:DC%2BC38XhtlygurvN, PID: 22028387
-
Pchejetski D, Foussal C, Alfarano C, Lairez O, Calise D, Guilbeau-Frugier C, Schaak S, Seguelas MH, Wanecq E, Valet P, Parini A, Kunduzova O (2012) Apelin prevents cardiac fibroblast activation and collagen production through inhibition of sphingosine kinase 1. Eur Heart J 33:2360–2369
-
(2012)
Eur Heart J
, vol.33
, pp. 2360-2369
-
-
Pchejetski, D.1
Foussal, C.2
Alfarano, C.3
Lairez, O.4
Calise, D.5
Guilbeau-Frugier, C.6
Schaak, S.7
Seguelas, M.H.8
Wanecq, E.9
Valet, P.10
Parini, A.11
Kunduzova, O.12
-
47
-
-
84905457703
-
AdipoR1/APPL1 potentiates the protective effects of globular adiponectin on angiotensin II-induced cardiac hypertrophy and fibrosis in neonatal rat atrial myocytes and fibroblasts
-
PID: 25099270
-
Cao T, Gao Z, Gu L, Chen M, Yang B, Cao K, Huang H, Li M (2014) AdipoR1/APPL1 potentiates the protective effects of globular adiponectin on angiotensin II-induced cardiac hypertrophy and fibrosis in neonatal rat atrial myocytes and fibroblasts. PLoS One 9:e103793
-
(2014)
PLoS One
, vol.9
-
-
Cao, T.1
Gao, Z.2
Gu, L.3
Chen, M.4
Yang, B.5
Cao, K.6
Huang, H.7
Li, M.8
-
48
-
-
84872224969
-
3,3′-Diindolylmethane protects against cardiac hypertrophy via 5′-adenosine monophosphate-activated protein kinase-alpha2
-
COI: 1:CAS:528:DC%2BC3sXht1SltrY%3D, PID: 23326427
-
Zong J, Deng W, Zhou H, Bian ZY, Dai J, Yuan Y, Zhang JY, Zhang R, Zhang Y, Wu QQ, Guo HP, Li HL, Tang QZ (2013) 3,3′-Diindolylmethane protects against cardiac hypertrophy via 5′-adenosine monophosphate-activated protein kinase-alpha2. PLoS One 8:e53427
-
(2013)
PLoS One
, vol.8
-
-
Zong, J.1
Deng, W.2
Zhou, H.3
Bian, Z.Y.4
Dai, J.5
Yuan, Y.6
Zhang, J.Y.7
Zhang, R.8
Zhang, Y.9
Wu, Q.Q.10
Guo, H.P.11
Li, H.L.12
Tang, Q.Z.13
-
49
-
-
84866287052
-
alpha-Lipoic acid attenuates cardiac fibrosis in Otsuka Long-Evans Tokushima Fatty rats
-
COI: 1:CAS:528:DC%2BC3sXjslCisb8%3D, PID: 22992429
-
Lee JE, Yi CO, Jeon BT, Shin HJ, Kim SK, Jung TS, Choi JY, Roh GS (2012) alpha-Lipoic acid attenuates cardiac fibrosis in Otsuka Long-Evans Tokushima Fatty rats. Cardiovasc Diabetol 11:111
-
(2012)
Cardiovasc Diabetol
, vol.11
, pp. 111
-
-
Lee, J.E.1
Yi, C.O.2
Jeon, B.T.3
Shin, H.J.4
Kim, S.K.5
Jung, T.S.6
Choi, J.Y.7
Roh, G.S.8
-
50
-
-
84948579774
-
CTRP3 attenuates post-infarct cardiac fibrosis by targeting Smad3 activation and inhibiting myofibroblast differentiation
-
COI: 1:CAS:528:DC%2BC2MXhtFChsLvL
-
Wu D, Lei H, Wang JY, Zhang CL, Feng H, Fu FY, Li L, Wu LL (2015) CTRP3 attenuates post-infarct cardiac fibrosis by targeting Smad3 activation and inhibiting myofibroblast differentiation. J Mol Med (Berl) 93:1311–1325
-
(2015)
J Mol Med (Berl)
, vol.93
, pp. 1311-1325
-
-
Wu, D.1
Lei, H.2
Wang, J.Y.3
Zhang, C.L.4
Feng, H.5
Fu, F.Y.6
Li, L.7
Wu, L.L.8
-
51
-
-
84961319891
-
AMPK in cardiac fibrosis and repair: actions beyond metabolic regulation
-
COI: 1:CAS:528:DC%2BC28XhtVens7Y%3D, PID: 26772531
-
Daskalopoulos EP, Dufeys C, Bertrand L, Beauloye C, Horman S (2016) AMPK in cardiac fibrosis and repair: actions beyond metabolic regulation. J Mol Cell Cardiol 91:188–200
-
(2016)
J Mol Cell Cardiol
, vol.91
, pp. 188-200
-
-
Daskalopoulos, E.P.1
Dufeys, C.2
Bertrand, L.3
Beauloye, C.4
Horman, S.5
-
52
-
-
84960488484
-
Overnourishment during lactation induces metabolic and haemodynamic heart impairment during adulthood
-
COI: 1:STN:280:DC%2BC287mvFOjsA%3D%3D, PID: 26315623
-
Vieira AK, Soares VM, Bernardo AF, Neves FA, Mattos AB, Guedes RM, Cortez E, Andrade DC, Lacerda-Miranda G, Garcia-Souza EP, Moura AS (2015) Overnourishment during lactation induces metabolic and haemodynamic heart impairment during adulthood. Nutr Metab Cardiovasc Dis 25:1062–1069
-
(2015)
Nutr Metab Cardiovasc Dis
, vol.25
, pp. 1062-1069
-
-
Vieira, A.K.1
Soares, V.M.2
Bernardo, A.F.3
Neves, F.A.4
Mattos, A.B.5
Guedes, R.M.6
Cortez, E.7
Andrade, D.C.8
Lacerda-Miranda, G.9
Garcia-Souza, E.P.10
Moura, A.S.11
-
53
-
-
67349222563
-
Anti-hypertrophic effect of NHE-1 inhibition involves GSK-3beta-dependent attenuation of mitochondrial dysfunction
-
COI: 1:CAS:528:DC%2BD1MXmtVSgs74%3D, PID: 19318234
-
Javadov S, Rajapurohitam V, Kilic A, Zeidan A, Choi A, Karmazyn M (2009) Anti-hypertrophic effect of NHE-1 inhibition involves GSK-3beta-dependent attenuation of mitochondrial dysfunction. J Mol Cell Cardiol 46:998–1007
-
(2009)
J Mol Cell Cardiol
, vol.46
, pp. 998-1007
-
-
Javadov, S.1
Rajapurohitam, V.2
Kilic, A.3
Zeidan, A.4
Choi, A.5
Karmazyn, M.6
-
54
-
-
84897959639
-
Crosstalk between AMPK activation and angiotensin II-induced hypertrophy in cardiomyocytes: the role of mitochondria
-
COI: 1:CAS:528:DC%2BC2cXmtVCjsrw%3D, PID: 24444314
-
Hernandez JS, Barreto-Torres G, Kuznetsov AV, Khuchua Z, Javadov S (2014) Crosstalk between AMPK activation and angiotensin II-induced hypertrophy in cardiomyocytes: the role of mitochondria. J Cell Mol Med 18:709–720
-
(2014)
J Cell Mol Med
, vol.18
, pp. 709-720
-
-
Hernandez, J.S.1
Barreto-Torres, G.2
Kuznetsov, A.V.3
Khuchua, Z.4
Javadov, S.5
-
55
-
-
42249101542
-
Metformin protects the ischemic heart by the Akt-mediated inhibition of mitochondrial permeability transition pore opening
-
COI: 1:CAS:528:DC%2BD1cXmtlSgtrY%3D, PID: 18080084
-
Bhamra GS, Hausenloy DJ, Davidson SM, Carr RD, Paiva M, Wynne AM, Mocanu MM, Yellon DM (2008) Metformin protects the ischemic heart by the Akt-mediated inhibition of mitochondrial permeability transition pore opening. Basic Res Cardiol 103:274–284
-
(2008)
Basic Res Cardiol
, vol.103
, pp. 274-284
-
-
Bhamra, G.S.1
Hausenloy, D.J.2
Davidson, S.M.3
Carr, R.D.4
Paiva, M.5
Wynne, A.M.6
Mocanu, M.M.7
Yellon, D.M.8
-
56
-
-
84953296173
-
AMPK is critical for mitochondrial function during reperfusion after myocardial ischemia
-
COI: 1:CAS:528:DC%2BC28XmslKjtA%3D%3D, PID: 26746142
-
Zaha VG, Qi D, Su KN, Palmeri M, Lee HY, Hu X, Wu X, Shulman GI, Rabinovitch PS, Russell RR 3rd, Young LH (2016) AMPK is critical for mitochondrial function during reperfusion after myocardial ischemia. J Mol Cell Cardiol 91:104–113
-
(2016)
J Mol Cell Cardiol
, vol.91
, pp. 104-113
-
-
Zaha, V.G.1
Qi, D.2
Su, K.N.3
Palmeri, M.4
Lee, H.Y.5
Hu, X.6
Wu, X.7
Shulman, G.I.8
Rabinovitch, P.S.9
Russell, R.R.10
Young, L.H.11
-
57
-
-
84926373007
-
The beneficial effects of AMP kinase activation against oxidative stress are associated with prevention of PPARalpha-cyclophilin D interaction in cardiomyocytes
-
COI: 1:CAS:528:DC%2BC2MXnvVWrsLg%3D, PID: 25617357
-
Barreto-Torres G, Hernandez JS, Jang S, Rodriguez-Munoz AR, Torres-Ramos CA, Basnakian AG, Javadov S (2015) The beneficial effects of AMP kinase activation against oxidative stress are associated with prevention of PPARalpha-cyclophilin D interaction in cardiomyocytes. Am J Physiol Heart Circ Physiol 308:H749–H758
-
(2015)
Am J Physiol Heart Circ Physiol
, vol.308
, pp. H749-H758
-
-
Barreto-Torres, G.1
Hernandez, J.S.2
Jang, S.3
Rodriguez-Munoz, A.R.4
Torres-Ramos, C.A.5
Basnakian, A.G.6
Javadov, S.7
-
58
-
-
63349109161
-
Clinical outcome and phenotypic expression in LAMP2 cardiomyopathy
-
COI: 1:CAS:528:DC%2BD1MXjs1GjtbY%3D, PID: 19318653
-
Maron BJ, Roberts WC, Arad M, Haas TS, Spirito P, Wright GB, Almquist AK, Baffa JM, Saul JP, Ho CY, Seidman J, Seidman CE (2009) Clinical outcome and phenotypic expression in LAMP2 cardiomyopathy. JAMA 301:1253–1259
-
(2009)
JAMA
, vol.301
, pp. 1253-1259
-
-
Maron, B.J.1
Roberts, W.C.2
Arad, M.3
Haas, T.S.4
Spirito, P.5
Wright, G.B.6
Almquist, A.K.7
Baffa, J.M.8
Saul, J.P.9
Ho, C.Y.10
Seidman, J.11
Seidman, C.E.12
-
59
-
-
61349177862
-
Long-term effects of enzyme replacement therapy on fabry cardiomyopathy: evidence for a better outcome with early treatment
-
COI: 1:CAS:528:DC%2BD1MXpt1ektw%3D%3D, PID: 19153271
-
Weidemann F, Niemann M, Breunig F, Herrmann S, Beer M, Stork S, Voelker W, Ertl G, Wanner C, Strotmann J (2009) Long-term effects of enzyme replacement therapy on fabry cardiomyopathy: evidence for a better outcome with early treatment. Circulation 119:524–529
-
(2009)
Circulation
, vol.119
, pp. 524-529
-
-
Weidemann, F.1
Niemann, M.2
Breunig, F.3
Herrmann, S.4
Beer, M.5
Stork, S.6
Voelker, W.7
Ertl, G.8
Wanner, C.9
Strotmann, J.10
-
60
-
-
20044391423
-
Adenosine monophosphate-activated protein kinase disease mimicks hypertrophic cardiomyopathy and Wolff–Parkinson–White syndrome: natural history
-
COI: 1:CAS:528:DC%2BD2MXit1Cju74%3D, PID: 15766830
-
Murphy RT, Mogensen J, McGarry K, Bahl A, Evans A, Osman E, Syrris P, Gorman G, Farrell M, Holton JL, Hanna MG, Hughes S, Elliott PM, Macrae CA, McKenna WJ (2005) Adenosine monophosphate-activated protein kinase disease mimicks hypertrophic cardiomyopathy and Wolff–Parkinson–White syndrome: natural history. J Am Coll Cardiol 45:922–930
-
(2005)
J Am Coll Cardiol
, vol.45
, pp. 922-930
-
-
Murphy, R.T.1
Mogensen, J.2
McGarry, K.3
Bahl, A.4
Evans, A.5
Osman, E.6
Syrris, P.7
Gorman, G.8
Farrell, M.9
Holton, J.L.10
Hanna, M.G.11
Hughes, S.12
Elliott, P.M.13
Macrae, C.A.14
McKenna, W.J.15
-
61
-
-
34447125085
-
A PRKAG2 mutation causes biphasic changes in myocardial AMPK activity and does not protect against ischemia
-
COI: 1:CAS:528:DC%2BD2sXnslSqtLc%3D, PID: 17597581
-
Banerjee SK, Ramani R, Saba S, Rager J, Tian R, Mathier MA, Ahmad F (2007) A PRKAG2 mutation causes biphasic changes in myocardial AMPK activity and does not protect against ischemia. Biochem Biophys Res Commun 360:381–387
-
(2007)
Biochem Biophys Res Commun
, vol.360
, pp. 381-387
-
-
Banerjee, S.K.1
Ramani, R.2
Saba, S.3
Rager, J.4
Tian, R.5
Mathier, M.A.6
Ahmad, F.7
-
62
-
-
0034654362
-
Characterization of AMP-activated protein kinase gamma-subunit isoforms and their role in AMP binding
-
COI: 1:CAS:528:DC%2BD3cXit1Krsr0%3D, PID: 10698692
-
Cheung PC, Salt IP, Davies SP, Hardie DG, Carling D (2000) Characterization of AMP-activated protein kinase gamma-subunit isoforms and their role in AMP binding. Biochem J 346(Pt 3):659–669
-
(2000)
Biochem J
, vol.346
, pp. 659-669
-
-
Cheung, P.C.1
Salt, I.P.2
Davies, S.P.3
Hardie, D.G.4
Carling, D.5
-
63
-
-
19944429566
-
Transgenic mouse model of ventricular preexcitation and atrioventricular reentrant tachycardia induced by an AMP-activated protein kinase loss-of-function mutation responsible for Wolff–Parkinson–White syndrome
-
COI: 1:CAS:528:DC%2BD2cXhtFeisLrP, PID: 15611370
-
Sidhu JS, Rajawat YS, Rami TG, Gollob MH, Wang Z, Yuan R, Marian AJ, DeMayo FJ, Weilbacher D, Taffet GE, Davies JK, Carling D, Khoury DS, Roberts R (2005) Transgenic mouse model of ventricular preexcitation and atrioventricular reentrant tachycardia induced by an AMP-activated protein kinase loss-of-function mutation responsible for Wolff–Parkinson–White syndrome. Circulation 111:21–29
-
(2005)
Circulation
, vol.111
, pp. 21-29
-
-
Sidhu, J.S.1
Rajawat, Y.S.2
Rami, T.G.3
Gollob, M.H.4
Wang, Z.5
Yuan, R.6
Marian, A.J.7
DeMayo, F.J.8
Weilbacher, D.9
Taffet, G.E.10
Davies, J.K.11
Carling, D.12
Khoury, D.S.13
Roberts, R.14
-
64
-
-
0037782349
-
Transgenic mice overexpressing mutant PRKAG2 define the cause of Wolff–Parkinson–White syndrome in glycogen storage cardiomyopathy
-
COI: 1:CAS:528:DC%2BD3sXktFyru74%3D, PID: 12782567
-
Arad M, Moskowitz IP, Patel VV, Ahmad F, Perez-Atayde AR, Sawyer DB, Walter M, Li GH, Burgon PG, Maguire CT, Stapleton D, Schmitt JP, Guo XX, Pizard A, Kupershmidt S, Roden DM, Berul CI, Seidman CE, Seidman JG (2003) Transgenic mice overexpressing mutant PRKAG2 define the cause of Wolff–Parkinson–White syndrome in glycogen storage cardiomyopathy. Circulation 107:2850–2856
-
(2003)
Circulation
, vol.107
, pp. 2850-2856
-
-
Arad, M.1
Moskowitz, I.P.2
Patel, V.V.3
Ahmad, F.4
Perez-Atayde, A.R.5
Sawyer, D.B.6
Walter, M.7
Li, G.H.8
Burgon, P.G.9
Maguire, C.T.10
Stapleton, D.11
Schmitt, J.P.12
Guo, X.X.13
Pizard, A.14
Kupershmidt, S.15
Roden, D.M.16
Berul, C.I.17
Seidman, C.E.18
Seidman, J.G.19
-
65
-
-
33745945268
-
A contemporary approach to hypertrophic cardiomyopathy
-
PID: 16785342
-
Ho CY, Seidman CE (2006) A contemporary approach to hypertrophic cardiomyopathy. Circulation 113:e858–e862
-
(2006)
Circulation
, vol.113
, pp. e858-e862
-
-
Ho, C.Y.1
Seidman, C.E.2
-
66
-
-
37549040201
-
Genetic basis of hypertrophic cardiomyopathy: from bench to the clinics
-
PID: 17916152
-
Alcalai R, Seidman JG, Seidman CE (2008) Genetic basis of hypertrophic cardiomyopathy: from bench to the clinics. J Cardiovasc Electrophysiol 19:104–110
-
(2008)
J Cardiovasc Electrophysiol
, vol.19
, pp. 104-110
-
-
Alcalai, R.1
Seidman, J.G.2
Seidman, C.E.3
-
67
-
-
0032580520
-
Mutations in the gene for cardiac myosin-binding protein C and late-onset familial hypertrophic cardiomyopathy
-
COI: 1:CAS:528:DyaK1cXivF2qtrY%3D, PID: 9562578
-
Niimura H, Bachinski LL, Sangwatanaroj S, Watkins H, Chudley AE, McKenna W, Kristinsson A, Roberts R, Sole M, Maron BJ, Seidman JG, Seidman CE (1998) Mutations in the gene for cardiac myosin-binding protein C and late-onset familial hypertrophic cardiomyopathy. N Engl J Med 338:1248–1257
-
(1998)
N Engl J Med
, vol.338
, pp. 1248-1257
-
-
Niimura, H.1
Bachinski, L.L.2
Sangwatanaroj, S.3
Watkins, H.4
Chudley, A.E.5
McKenna, W.6
Kristinsson, A.7
Roberts, R.8
Sole, M.9
Maron, B.J.10
Seidman, J.G.11
Seidman, C.E.12
-
68
-
-
67649854428
-
Diagnostic, prognostic, and therapeutic implications of genetic testing for hypertrophic cardiomyopathy
-
COI: 1:CAS:528:DC%2BD1MXpvFyntrY%3D, PID: 19589432
-
Bos JM, Towbin JA, Ackerman MJ (2009) Diagnostic, prognostic, and therapeutic implications of genetic testing for hypertrophic cardiomyopathy. J Am Coll Cardiol 54:201–211
-
(2009)
J Am Coll Cardiol
, vol.54
, pp. 201-211
-
-
Bos, J.M.1
Towbin, J.A.2
Ackerman, M.J.3
-
69
-
-
84858782079
-
AMPK: a nutrient and energy sensor that maintains energy homeostasis
-
COI: 1:CAS:528:DC%2BC38XksVenu7w%3D, PID: 22436748
-
Hardie DG, Ross FA, Hawley SA (2012) AMPK: a nutrient and energy sensor that maintains energy homeostasis. Nat Rev Mol Cell Biol 13:251–262
-
(2012)
Nat Rev Mol Cell Biol
, vol.13
, pp. 251-262
-
-
Hardie, D.G.1
Ross, F.A.2
Hawley, S.A.3
-
70
-
-
0026651085
-
Wine, alcohol, platelets, and the French paradox for coronary heart disease
-
COI: 1:STN:280:DyaK383pt1ygtA%3D%3D, PID: 1351198
-
Renaud S, de Lorgeril M (1992) Wine, alcohol, platelets, and the French paradox for coronary heart disease. Lancet 339:1523–1526
-
(1992)
Lancet
, vol.339
, pp. 1523-1526
-
-
Renaud, S.1
de Lorgeril, M.2
-
71
-
-
84859524897
-
The polyphenols resveratrol and S17834 prevent the structural and functional sequelae of diet-induced metabolic heart disease in mice
-
Qin F, Siwik DA, Luptak I, Hou X, Wang L, Higuchi A, Weisbrod RM, Ouchi N, Tu VH, Calamaras TD, Miller EJ, Verbeuren TJ, Walsh K, Cohen RA, Colucci WS (2012) The polyphenols resveratrol and S17834 prevent the structural and functional sequelae of diet-induced metabolic heart disease in mice. Circulation 125(1757–1764):S1751–S1756
-
(2012)
Circulation
, vol.125
, Issue.1757-1764
, pp. S1751-S1756
-
-
Qin, F.1
Siwik, D.A.2
Luptak, I.3
Hou, X.4
Wang, L.5
Higuchi, A.6
Weisbrod, R.M.7
Ouchi, N.8
Tu, V.H.9
Calamaras, T.D.10
Miller, E.J.11
Verbeuren, T.J.12
Walsh, K.13
Cohen, R.A.14
Colucci, W.S.15
-
72
-
-
73549093854
-
The natriuretic peptide uroguanylin elicits physiologic actions through 2 distinct topoisomers
-
COI: 1:CAS:528:DC%2BD1MXksFeit7o%3D, PID: 19289652
-
Moss NG, Riguera DA, Solinga RM, Kessler MM, Zimmer DP, Arendshorst WJ, Currie MG, Goy MF (2009) The natriuretic peptide uroguanylin elicits physiologic actions through 2 distinct topoisomers. Hypertension 53:867–876
-
(2009)
Hypertension
, vol.53
, pp. 867-876
-
-
Moss, N.G.1
Riguera, D.A.2
Solinga, R.M.3
Kessler, M.M.4
Zimmer, D.P.5
Arendshorst, W.J.6
Currie, M.G.7
Goy, M.F.8
-
73
-
-
80052051692
-
Resveratrol prevents norepinephrine induced hypertrophy in adult rat cardiomyocytes, by activating NO-AMPK pathway
-
COI: 1:CAS:528:DC%2BC3MXhtV2itrfP, PID: 21756902
-
Thandapilly SJ, Louis XL, Yang T, Stringer DM, Yu L, Zhang S, Wigle J, Kardami E, Zahradka P, Taylor C, Anderson HD, Netticadan T (2011) Resveratrol prevents norepinephrine induced hypertrophy in adult rat cardiomyocytes, by activating NO-AMPK pathway. Eur J Pharmacol 668:217–224
-
(2011)
Eur J Pharmacol
, vol.668
, pp. 217-224
-
-
Thandapilly, S.J.1
Louis, X.L.2
Yang, T.3
Stringer, D.M.4
Yu, L.5
Zhang, S.6
Wigle, J.7
Kardami, E.8
Zahradka, P.9
Taylor, C.10
Anderson, H.D.11
Netticadan, T.12
-
74
-
-
84937809888
-
Therapeutic potential of resveratrol in heart failure
-
COI: 1:CAS:528:DC%2BC2MXhsl2htbjP, PID: 26205211
-
Sung MM, Dyck JR (2015) Therapeutic potential of resveratrol in heart failure. Ann N Y Acad Sci 1348:32–45
-
(2015)
Ann N Y Acad Sci
, vol.1348
, pp. 32-45
-
-
Sung, M.M.1
Dyck, J.R.2
-
75
-
-
33947574510
-
Long-term activation of adenosine monophosphate-activated protein kinase attenuates pressure-overload-induced cardiac hypertrophy
-
COI: 1:CAS:528:DC%2BD2sXjs1amtrw%3D, PID: 17266062
-
Li HL, Yin R, Chen D, Liu D, Wang D, Yang Q, Dong YG (2007) Long-term activation of adenosine monophosphate-activated protein kinase attenuates pressure-overload-induced cardiac hypertrophy. J Cell Biochem 100:1086–1099
-
(2007)
J Cell Biochem
, vol.100
, pp. 1086-1099
-
-
Li, H.L.1
Yin, R.2
Chen, D.3
Liu, D.4
Wang, D.5
Yang, Q.6
Dong, Y.G.7
-
76
-
-
84929177057
-
Metformin activates a duodenal Ampk-dependent pathway to lower hepatic glucose production in rats
-
COI: 1:CAS:528:DC%2BC2MXmtlKktLw%3D, PID: 25849133
-
Duca FA, Cote CD, Rasmussen BA, Zadeh-Tahmasebi M, Rutter GA, Filippi BM, Lam TK (2015) Metformin activates a duodenal Ampk-dependent pathway to lower hepatic glucose production in rats. Nat Med 21:506–511
-
(2015)
Nat Med
, vol.21
, pp. 506-511
-
-
Duca, F.A.1
Cote, C.D.2
Rasmussen, B.A.3
Zadeh-Tahmasebi, M.4
Rutter, G.A.5
Filippi, B.M.6
Lam, T.K.7
-
77
-
-
67349276169
-
+ metabolism and SIRT1 activity
-
COI: 1:CAS:528:DC%2BD1MXivVKltLc%3D, PID: 19262508
-
+ metabolism and SIRT1 activity. Nature 458:1056–1060
-
(2009)
Nature
, vol.458
, pp. 1056-1060
-
-
Canto, C.1
Gerhart-Hines, Z.2
Feige, J.N.3
Lagouge, M.4
Noriega, L.5
Milne, J.C.6
Elliott, P.J.7
Puigserver, P.8
Auwerx, J.9
-
78
-
-
84903524608
-
Metformin suppresses gluconeogenesis by inhibiting mitochondrial glycerophosphate dehydrogenase
-
COI: 1:CAS:528:DC%2BC2cXpslGitLg%3D, PID: 24847880
-
Madiraju AK, Erion DM, Rahimi Y, Zhang XM, Braddock DT, Albright RA, Prigaro BJ, Wood JL, Bhanot S, MacDonald MJ, Jurczak MJ, Camporez JP, Lee HY, Cline GW, Samuel VT, Kibbey RG, Shulman GI (2014) Metformin suppresses gluconeogenesis by inhibiting mitochondrial glycerophosphate dehydrogenase. Nature 510:542–546
-
(2014)
Nature
, vol.510
, pp. 542-546
-
-
Madiraju, A.K.1
Erion, D.M.2
Rahimi, Y.3
Zhang, X.M.4
Braddock, D.T.5
Albright, R.A.6
Prigaro, B.J.7
Wood, J.L.8
Bhanot, S.9
MacDonald, M.J.10
Jurczak, M.J.11
Camporez, J.P.12
Lee, H.Y.13
Cline, G.W.14
Samuel, V.T.15
Kibbey, R.G.16
Shulman, G.I.17
-
79
-
-
40949087724
-
Acute metformin therapy confers cardioprotection against myocardial infarction via AMPK-eNOS-mediated signaling
-
COI: 1:CAS:528:DC%2BD1cXjt1Chtbc%3D, PID: 18083782
-
Calvert JW, Gundewar S, Jha S, Greer JJ, Bestermann WH, Tian R, Lefer DJ (2008) Acute metformin therapy confers cardioprotection against myocardial infarction via AMPK-eNOS-mediated signaling. Diabetes 57:696–705
-
(2008)
Diabetes
, vol.57
, pp. 696-705
-
-
Calvert, J.W.1
Gundewar, S.2
Jha, S.3
Greer, J.J.4
Bestermann, W.H.5
Tian, R.6
Lefer, D.J.7
-
80
-
-
84991236882
-
The role of PPARalpha in metformin-induced attenuation of mitochondrial dysfunction in acute cardiac ischemia/reperfusion in rats
-
COI: 1:CAS:528:DC%2BC38XpsFSksrs%3D, PID: 22837722
-
Barreto-Torres G, Parodi-Rullan R, Javadov S (2012) The role of PPARalpha in metformin-induced attenuation of mitochondrial dysfunction in acute cardiac ischemia/reperfusion in rats. Int J Mol Sci 13:7694–7709
-
(2012)
Int J Mol Sci
, vol.13
, pp. 7694-7709
-
-
Barreto-Torres, G.1
Parodi-Rullan, R.2
Javadov, S.3
-
81
-
-
61949300140
-
Activation of AMP-activated protein kinase by metformin improves left ventricular function and survival in heart failure
-
COI: 1:CAS:528:DC%2BD1MXhsV2jsLY%3D, PID: 19096023
-
Gundewar S, Calvert JW, Jha S, Toedt-Pingel I, Ji SY, Nunez D, Ramachandran A, Anaya-Cisneros M, Tian R, Lefer DJ (2009) Activation of AMP-activated protein kinase by metformin improves left ventricular function and survival in heart failure. Circ Res 104:403–411
-
(2009)
Circ Res
, vol.104
, pp. 403-411
-
-
Gundewar, S.1
Calvert, J.W.2
Jha, S.3
Toedt-Pingel, I.4
Ji, S.Y.5
Nunez, D.6
Ramachandran, A.7
Anaya-Cisneros, M.8
Tian, R.9
Lefer, D.J.10
-
82
-
-
78650658243
-
Metformin attenuates ventricular hypertrophy by activating the AMP-activated protein kinase-endothelial nitric oxide synthase pathway in rats
-
PID: 21083698
-
Zhang CX, Pan SN, Meng RS, Peng CQ, Xiong ZJ, Chen BL, Chen GQ, Yao FJ, Chen YL, Ma YD, Dong YG (2011) Metformin attenuates ventricular hypertrophy by activating the AMP-activated protein kinase-endothelial nitric oxide synthase pathway in rats. Clin Exp Pharmacol Physiol 38:55–62
-
(2011)
Clin Exp Pharmacol Physiol
, vol.38
, pp. 55-62
-
-
Zhang, C.X.1
Pan, S.N.2
Meng, R.S.3
Peng, C.Q.4
Xiong, Z.J.5
Chen, B.L.6
Chen, G.Q.7
Yao, F.J.8
Chen, Y.L.9
Ma, Y.D.10
Dong, Y.G.11
-
84
-
-
84964788275
-
Risk of bias in systematic reviews of non-randomized studies of adverse cardiovascular effects of thiazolidinediones and cyclooxygenase-2 inhibitors: application of a new Cochrane risk of bias tool
-
PID: 27046153
-
Bilandzic A, Fitzpatrick T, Rosella L, Henry D (2016) Risk of bias in systematic reviews of non-randomized studies of adverse cardiovascular effects of thiazolidinediones and cyclooxygenase-2 inhibitors: application of a new Cochrane risk of bias tool. PLoS Med 13:e1001987
-
(2016)
PLoS Med
, vol.13
-
-
Bilandzic, A.1
Fitzpatrick, T.2
Rosella, L.3
Henry, D.4
-
85
-
-
11144283125
-
Role of PP2C in cardiac lipid accumulation in obese rodents and its prevention by troglitazone
-
COI: 1:CAS:528:DC%2BD2MXhtVGju7g%3D, PID: 15367397
-
Wang MY, Unger RH (2005) Role of PP2C in cardiac lipid accumulation in obese rodents and its prevention by troglitazone. Am J Physiol Endocrinol Metab 288:E216–E221
-
(2005)
Am J Physiol Endocrinol Metab
, vol.288
, pp. E216-E221
-
-
Wang, M.Y.1
Unger, R.H.2
-
86
-
-
73849096181
-
Evidence for the importance of adiponectin in the cardioprotective effects of pioglitazone
-
COI: 1:CAS:528:DC%2BD1MXhsFaqt7fJ, PID: 19933924
-
Li P, Shibata R, Unno K, Shimano M, Furukawa M, Ohashi T, Cheng X, Nagata K, Ouchi N, Murohara T (2010) Evidence for the importance of adiponectin in the cardioprotective effects of pioglitazone. Hypertension 55:69–75
-
(2010)
Hypertension
, vol.55
, pp. 69-75
-
-
Li, P.1
Shibata, R.2
Unno, K.3
Shimano, M.4
Furukawa, M.5
Ohashi, T.6
Cheng, X.7
Nagata, K.8
Ouchi, N.9
Murohara, T.10
-
87
-
-
51549114941
-
Pioglitazone attenuates cardiac hypertrophy in rats with salt-sensitive hypertension: role of activation of AMP-activated protein kinase and inhibition of Akt
-
COI: 1:CAS:528:DC%2BD1cXosVertb8%3D, PID: 18622247
-
Kato MF, Shibata R, Obata K, Miyachi M, Yazawa H, Tsuboi K, Yamada T, Nishizawa T, Noda A, Cheng XW, Murate T, Koike Y, Murohara T, Yokota M, Nagata K (2008) Pioglitazone attenuates cardiac hypertrophy in rats with salt-sensitive hypertension: role of activation of AMP-activated protein kinase and inhibition of Akt. J Hypertens 26:1669–1676
-
(2008)
J Hypertens
, vol.26
, pp. 1669-1676
-
-
Kato, M.F.1
Shibata, R.2
Obata, K.3
Miyachi, M.4
Yazawa, H.5
Tsuboi, K.6
Yamada, T.7
Nishizawa, T.8
Noda, A.9
Cheng, X.W.10
Murate, T.11
Koike, Y.12
Murohara, T.13
Yokota, M.14
Nagata, K.15
-
88
-
-
33744514139
-
Identification and characterization of a small molecule AMPK activator that treats key components of type 2 diabetes and the metabolic syndrome
-
COI: 1:CAS:528:DC%2BD28Xmt1eku70%3D, PID: 16753576
-
Cool B, Zinker B, Chiou W, Kifle L, Cao N, Perham M, Dickinson R, Adler A, Gagne G, Iyengar R, Zhao G, Marsh K, Kym P, Jung P, Camp HS, Frevert E (2006) Identification and characterization of a small molecule AMPK activator that treats key components of type 2 diabetes and the metabolic syndrome. Cell Metab 3:403–416
-
(2006)
Cell Metab
, vol.3
, pp. 403-416
-
-
Cool, B.1
Zinker, B.2
Chiou, W.3
Kifle, L.4
Cao, N.5
Perham, M.6
Dickinson, R.7
Adler, A.8
Gagne, G.9
Iyengar, R.10
Zhao, G.11
Marsh, K.12
Kym, P.13
Jung, P.14
Camp, H.S.15
Frevert, E.16
-
89
-
-
84901332717
-
A-769662 potentiates the effect of other AMP-activated protein kinase activators on cardiac glucose uptake
-
COI: 1:CAS:528:DC%2BC2cXhtFalurvN, PID: 24748590
-
Timmermans AD, Balteau M, Gelinas R, Renguet E, Ginion A, de Meester C, Sakamoto K, Balligand JL, Bontemps F, Vanoverschelde JL, Horman S, Beauloye C, Bertrand L (2014) A-769662 potentiates the effect of other AMP-activated protein kinase activators on cardiac glucose uptake. Am J Physiol Heart Circ Physiol 306:H1619–H1630
-
(2014)
Am J Physiol Heart Circ Physiol
, vol.306
, pp. H1619-H1630
-
-
Timmermans, A.D.1
Balteau, M.2
Gelinas, R.3
Renguet, E.4
Ginion, A.5
de Meester, C.6
Sakamoto, K.7
Balligand, J.L.8
Bontemps, F.9
Vanoverschelde, J.L.10
Horman, S.11
Beauloye, C.12
Bertrand, L.13
-
90
-
-
78651319319
-
Activation of AMPK stimulates heme oxygenase-1 gene expression and human endothelial cell survival
-
COI: 1:CAS:528:DC%2BC3MXhslWgur4%3D, PID: 21037234
-
Liu XM, Peyton KJ, Shebib AR, Wang H, Korthuis RJ, Durante W (2011) Activation of AMPK stimulates heme oxygenase-1 gene expression and human endothelial cell survival. Am J Physiol Heart Circ Physiol 300:H84–H93
-
(2011)
Am J Physiol Heart Circ Physiol
, vol.300
, pp. H84-H93
-
-
Liu, X.M.1
Peyton, K.J.2
Shebib, A.R.3
Wang, H.4
Korthuis, R.J.5
Durante, W.6
-
91
-
-
79958034358
-
Enhancing AMPK activation during ischemia protects the diabetic heart against reperfusion injury
-
COI: 1:CAS:528:DC%2BC3MXot1Gkurc%3D, PID: 21421816
-
Paiva MA, Rutter-Locher Z, Goncalves LM, Providencia LA, Davidson SM, Yellon DM, Mocanu MM (2011) Enhancing AMPK activation during ischemia protects the diabetic heart against reperfusion injury. Am J Physiol Heart Circ Physiol 300:H2123–H2134
-
(2011)
Am J Physiol Heart Circ Physiol
, vol.300
, pp. H2123-H2134
-
-
Paiva, M.A.1
Rutter-Locher, Z.2
Goncalves, L.M.3
Providencia, L.A.4
Davidson, S.M.5
Yellon, D.M.6
Mocanu, M.M.7
-
92
-
-
84961916164
-
Possible role of interaction between PPARalpha and cyclophilin D in cardioprotection of AMPK against in vivo ischemia–reperfusion in rats
-
PID: 27051413
-
Barreto-Torres G, Javadov S (2016) Possible role of interaction between PPARalpha and cyclophilin D in cardioprotection of AMPK against in vivo ischemia–reperfusion in rats. PPAR Res 2016:9282087
-
(2016)
PPAR Res
, vol.2016
, pp. 9282087
-
-
Barreto-Torres, G.1
Javadov, S.2
-
93
-
-
79956298543
-
A small molecule AMPK activator protects the heart against ischemia–reperfusion injury
-
COI: 1:CAS:528:DC%2BC3MXmslyisrY%3D, PID: 21402077
-
Kim AS, Miller EJ, Wright TM, Li J, Qi D, Atsina K, Zaha V, Sakamoto K, Young LH (2011) A small molecule AMPK activator protects the heart against ischemia–reperfusion injury. J Mol Cell Cardiol 51:24–32
-
(2011)
J Mol Cell Cardiol
, vol.51
, pp. 24-32
-
-
Kim, A.S.1
Miller, E.J.2
Wright, T.M.3
Li, J.4
Qi, D.5
Atsina, K.6
Zaha, V.7
Sakamoto, K.8
Young, L.H.9
-
94
-
-
84896352484
-
Aerobic interval training protects against myocardial infarction-induced oxidative injury by enhancing antioxidase system and mitochondrial biosynthesis
-
PID: 24471974
-
Jiang HK, Miao Y, Wang YH, Zhao M, Feng ZH, Yu XJ, Liu JK, Zang WJ (2014) Aerobic interval training protects against myocardial infarction-induced oxidative injury by enhancing antioxidase system and mitochondrial biosynthesis. Clin Exp Pharmacol Physiol 41:192–201
-
(2014)
Clin Exp Pharmacol Physiol
, vol.41
, pp. 192-201
-
-
Jiang, H.K.1
Miao, Y.2
Wang, Y.H.3
Zhao, M.4
Feng, Z.H.5
Yu, X.J.6
Liu, J.K.7
Zang, W.J.8
-
95
-
-
84916606163
-
Exercise training prevents the attenuation of anesthetic pre-conditioning-mediated cardioprotection in diet-induced obese rats
-
COI: 1:CAS:528:DC%2BC2cXitVylt73I, PID: 25312305
-
Li L, Meng F, Li N, Zhang L, Wang J, Wang H, Li D, Zhang X, Dong P, Chen Y (2015) Exercise training prevents the attenuation of anesthetic pre-conditioning-mediated cardioprotection in diet-induced obese rats. Acta Anaesthesiol Scand 59:85–97
-
(2015)
Acta Anaesthesiol Scand
, vol.59
, pp. 85-97
-
-
Li, L.1
Meng, F.2
Li, N.3
Zhang, L.4
Wang, J.5
Wang, H.6
Li, D.7
Zhang, X.8
Dong, P.9
Chen, Y.10
-
96
-
-
0030700612
-
Predictive genetic testing: from basic research to clinical practice
-
COI: 1:CAS:528:DyaK2sXmvVOrsL4%3D, PID: 9381169
-
Holtzman NA, Murphy PD, Watson MS, Barr PA (1997) Predictive genetic testing: from basic research to clinical practice. Science 278:602–605
-
(1997)
Science
, vol.278
, pp. 602-605
-
-
Holtzman, N.A.1
Murphy, P.D.2
Watson, M.S.3
Barr, P.A.4
-
97
-
-
0037048668
-
Limitations of direct-to-consumer advertising for clinical genetic testing
-
PID: 12365961
-
Gollust SE, Hull SC, Wilfond BS (2002) Limitations of direct-to-consumer advertising for clinical genetic testing. JAMA 288:1762–1767
-
(2002)
JAMA
, vol.288
, pp. 1762-1767
-
-
Gollust, S.E.1
Hull, S.C.2
Wilfond, B.S.3
-
98
-
-
71649109002
-
Use of genetics in the clinical evaluation of cardiomyopathy
-
COI: 1:CAS:528:DC%2BD1MXhsFCntLbJ, PID: 19996403
-
Judge DP (2009) Use of genetics in the clinical evaluation of cardiomyopathy. JAMA 302:2471–2476
-
(2009)
JAMA
, vol.302
, pp. 2471-2476
-
-
Judge, D.P.1
-
99
-
-
0030066573
-
Molecular genetic insights into cardiovascular disease
-
COI: 1:CAS:528:DyaK28Xislamsb4%3D, PID: 8614827
-
Keating MT, Sanguinetti MC (1996) Molecular genetic insights into cardiovascular disease. Science 272:681–685
-
(1996)
Science
, vol.272
, pp. 681-685
-
-
Keating, M.T.1
Sanguinetti, M.C.2
-
100
-
-
70350741312
-
Implications of hypertrophic cardiomyopathy transmitted by sperm donation
-
COI: 1:CAS:528:DC%2BD1MXhtlWqs7%2FN, PID: 19843903
-
Maron BJ, Lesser JR, Schiller NB, Harris KM, Brown C, Rehm HL (2009) Implications of hypertrophic cardiomyopathy transmitted by sperm donation. JAMA 302:1681–1684
-
(2009)
JAMA
, vol.302
, pp. 1681-1684
-
-
Maron, B.J.1
Lesser, J.R.2
Schiller, N.B.3
Harris, K.M.4
Brown, C.5
Rehm, H.L.6
-
101
-
-
0030800933
-
Detection of familial primary pulmonary hypertension by genetic testing
-
COI: 1:STN:280:DyaK2szkslagsw%3D%3D, PID: 9221353
-
Morse JH, Barst RJ (1997) Detection of familial primary pulmonary hypertension by genetic testing. N Engl J Med 337:202–203
-
(1997)
N Engl J Med
, vol.337
, pp. 202-203
-
-
Morse, J.H.1
Barst, R.J.2
-
102
-
-
0026771521
-
Primary aldosteronism: hypertension with a genetic basis
-
COI: 1:STN:280:DyaK38zis1Cktg%3D%3D, PID: 1352575
-
Gordon RD, Klemm SA, Tunny TJ, Stowasser M (1992) Primary aldosteronism: hypertension with a genetic basis. Lancet 340:159–161
-
(1992)
Lancet
, vol.340
, pp. 159-161
-
-
Gordon, R.D.1
Klemm, S.A.2
Tunny, T.J.3
Stowasser, M.4
-
103
-
-
80051774386
-
A case of familial hypertrophic cardiomyopathy emphasizes the importance of parallel screening of multiple disease genes
-
PID: 21409595
-
Scheffold T, Waldmuller S, Borisov K (2011) A case of familial hypertrophic cardiomyopathy emphasizes the importance of parallel screening of multiple disease genes. Clin Res Cardiol 100:627–628
-
(2011)
Clin Res Cardiol
, vol.100
, pp. 627-628
-
-
Scheffold, T.1
Waldmuller, S.2
Borisov, K.3
-
104
-
-
84885460914
-
Cardiac transplant in a family pedigree of hypertrophic cardiomyopathy secondary to a mutation in the AMP gene
-
Schofield RS, McGarry K, Murphy CL, O’Hare K (2013) Cardiac transplant in a family pedigree of hypertrophic cardiomyopathy secondary to a mutation in the AMP gene. BMJ Case Rep. doi:10.1136/bcr-2013-009929
-
(2013)
BMJ Case Rep
-
-
Schofield, R.S.1
McGarry, K.2
Murphy, C.L.3
O’Hare, K.4
-
105
-
-
34748825648
-
Fatal infantile cardiac glycogenosis with phosphorylase kinase deficiency and a mutation in the gamma2-subunit of AMP-activated protein kinase
-
COI: 1:CAS:528:DC%2BD2sXhtVejtrjN, PID: 17667862
-
Akman HO, Sampayo JN, Ross FA, Scott JW, Wilson G, Benson L, Bruno C, Shanske S, Hardie DG, Dimauro S (2007) Fatal infantile cardiac glycogenosis with phosphorylase kinase deficiency and a mutation in the gamma2-subunit of AMP-activated protein kinase. Pediatr Res 62:499–504
-
(2007)
Pediatr Res
, vol.62
, pp. 499-504
-
-
Akman, H.O.1
Sampayo, J.N.2
Ross, F.A.3
Scott, J.W.4
Wilson, G.5
Benson, L.6
Bruno, C.7
Shanske, S.8
Hardie, D.G.9
Dimauro, S.10
-
106
-
-
84878607812
-
Identification of a novel de novo mutation associated with PRKAG2 cardiac syndrome and early onset of heart failure
-
COI: 1:CAS:528:DC%2BC3sXpslOgsbc%3D, PID: 23741347
-
Liu Y, Bai R, Wang L, Zhang C, Zhao R, Wan D, Chen X, Caceres G, Barr D, Barajas-Martinez H, Antzelevitch C, Hu D (2013) Identification of a novel de novo mutation associated with PRKAG2 cardiac syndrome and early onset of heart failure. PLoS One 8:e64603
-
(2013)
PLoS One
, vol.8
-
-
Liu, Y.1
Bai, R.2
Wang, L.3
Zhang, C.4
Zhao, R.5
Wan, D.6
Chen, X.7
Caceres, G.8
Barr, D.9
Barajas-Martinez, H.10
Antzelevitch, C.11
Hu, D.12
-
107
-
-
33745204925
-
AMPK alterations in cardiac physiology and pathology: enemy or ally?
-
COI: 1:CAS:528:DC%2BD28XnsVyju7k%3D, PID: 16690706
-
Dyck JR, Lopaschuk GD (2006) AMPK alterations in cardiac physiology and pathology: enemy or ally? J Physiol 574:95–112
-
(2006)
J Physiol
, vol.574
, pp. 95-112
-
-
Dyck, J.R.1
Lopaschuk, G.D.2
-
108
-
-
84882976310
-
Testosterone increases GLUT4-dependent glucose uptake in cardiomyocytes
-
COI: 1:CAS:528:DC%2BC3sXhtlWlurfF, PID: 23757167
-
Wilson C, Contreras-Ferrat A, Venegas N, Osorio-Fuentealba C, Pavez M, Montoya K, Duran J, Maass R, Lavandero S, Estrada M (2013) Testosterone increases GLUT4-dependent glucose uptake in cardiomyocytes. J Cell Physiol 228:2399–2407
-
(2013)
J Cell Physiol
, vol.228
, pp. 2399-2407
-
-
Wilson, C.1
Contreras-Ferrat, A.2
Venegas, N.3
Osorio-Fuentealba, C.4
Pavez, M.5
Montoya, K.6
Duran, J.7
Maass, R.8
Lavandero, S.9
Estrada, M.10
-
109
-
-
78149279712
-
AMP-activated protein kinase mediates ischemic glucose uptake and prevents postischemic cardiac dysfunction, apoptosis, and injury
-
COI: 1:CAS:528:DC%2BD2cXmvVelsr4%3D, PID: 15314686
-
Russell RR 3rd, Li J, Coven DL, Pypaert M, Zechner C, Palmeri M, Giordano FJ, Mu J, Birnbaum MJ, Young LH (2004) AMP-activated protein kinase mediates ischemic glucose uptake and prevents postischemic cardiac dysfunction, apoptosis, and injury. J Clin Invest 114:495–503
-
(2004)
J Clin Invest
, vol.114
, pp. 495-503
-
-
Russell, R.R.1
Li, J.2
Coven, D.L.3
Pypaert, M.4
Zechner, C.5
Palmeri, M.6
Giordano, F.J.7
Mu, J.8
Birnbaum, M.J.9
Young, L.H.10
-
110
-
-
0041707843
-
Glucose metabolism and energy homeostasis in mouse hearts overexpressing dominant negative alpha2 subunit of AMP-activated protein kinase
-
COI: 1:CAS:528:DC%2BD3sXlsl2ntrs%3D, PID: 12766162
-
Xing Y, Musi N, Fujii N, Zou L, Luptak I, Hirshman MF, Goodyear LJ, Tian R (2003) Glucose metabolism and energy homeostasis in mouse hearts overexpressing dominant negative alpha2 subunit of AMP-activated protein kinase. J Biol Chem 278:28372–28377
-
(2003)
J Biol Chem
, vol.278
, pp. 28372-28377
-
-
Xing, Y.1
Musi, N.2
Fujii, N.3
Zou, L.4
Luptak, I.5
Hirshman, M.F.6
Goodyear, L.J.7
Tian, R.8
-
111
-
-
0035859215
-
Identification of a gene responsible for familial Wolff–Parkinson–White syndrome
-
COI: 1:CAS:528:DC%2BD3MXltVOgtrk%3D, PID: 11407343
-
Gollob MH, Green MS, Tang AS, Gollob T, Karibe A, Ali Hassan AS, Ahmad F, Lozado R, Shah G, Fananapazir L, Bachinski LL, Roberts R (2001) Identification of a gene responsible for familial Wolff–Parkinson–White syndrome. N Engl J Med 344:1823–1831
-
(2001)
N Engl J Med
, vol.344
, pp. 1823-1831
-
-
Gollob, M.H.1
Green, M.S.2
Tang, A.S.3
Gollob, T.4
Karibe, A.5
Ali Hassan, A.S.6
Ahmad, F.7
Lozado, R.8
Shah, G.9
Fananapazir, L.10
Bachinski, L.L.11
Roberts, R.12
-
112
-
-
33646397564
-
Characterization of the role of gamma2 R531G mutation in AMP-activated protein kinase in cardiac hypertrophy and Wolff–Parkinson–White syndrome
-
COI: 1:CAS:528:DC%2BD28XkvFSmsbk%3D, PID: 16339829
-
Davies JK, Wells DJ, Liu K, Whitrow HR, Daniel TD, Grignani R, Lygate CA, Schneider JE, Noel G, Watkins H, Carling D (2006) Characterization of the role of gamma2 R531G mutation in AMP-activated protein kinase in cardiac hypertrophy and Wolff–Parkinson–White syndrome. Am J Physiol Heart Circ Physiol 290:H1942–H1951
-
(2006)
Am J Physiol Heart Circ Physiol
, vol.290
, pp. H1942-H1951
-
-
Davies, J.K.1
Wells, D.J.2
Liu, K.3
Whitrow, H.R.4
Daniel, T.D.5
Grignani, R.6
Lygate, C.A.7
Schneider, J.E.8
Noel, G.9
Watkins, H.10
Carling, D.11
-
113
-
-
0042364977
-
Electrophysiologic characterization and postnatal development of ventricular pre-excitation in a mouse model of cardiac hypertrophy and Wolff–Parkinson–White syndrome
-
PID: 12957447
-
Patel VV, Arad M, Moskowitz IP, Maguire CT, Branco D, Seidman JG, Seidman CE, Berul CI (2003) Electrophysiologic characterization and postnatal development of ventricular pre-excitation in a mouse model of cardiac hypertrophy and Wolff–Parkinson–White syndrome. J Am Coll Cardiol 42:942–951
-
(2003)
J Am Coll Cardiol
, vol.42
, pp. 942-951
-
-
Patel, V.V.1
Arad, M.2
Moskowitz, I.P.3
Maguire, C.T.4
Branco, D.5
Seidman, J.G.6
Seidman, C.E.7
Berul, C.I.8
-
114
-
-
84862784621
-
AMP-activated protein kinase phosphorylates cardiac troponin I and alters contractility of murine ventricular myocytes
-
COI: 1:CAS:528:DC%2BC38Xmt1KqsL8%3D, PID: 22456184
-
Oliveira SM, Zhang YH, Solis RS, Isackson H, Bellahcene M, Yavari A, Pinter K, Davies JK, Ge Y, Ashrafian H, Walker JW, Carling D, Watkins H, Casadei B, Redwood C (2012) AMP-activated protein kinase phosphorylates cardiac troponin I and alters contractility of murine ventricular myocytes. Circ Res 110:1192–1201
-
(2012)
Circ Res
, vol.110
, pp. 1192-1201
-
-
Oliveira, S.M.1
Zhang, Y.H.2
Solis, R.S.3
Isackson, H.4
Bellahcene, M.5
Yavari, A.6
Pinter, K.7
Davies, J.K.8
Ge, Y.9
Ashrafian, H.10
Walker, J.W.11
Carling, D.12
Watkins, H.13
Casadei, B.14
Redwood, C.15
-
115
-
-
6044224889
-
Cardiac mitochondrial damage and biogenesis in a chronic model of type 1 diabetes
-
COI: 1:CAS:528:DC%2BD2cXhtVaqs7rN, PID: 15280150
-
Shen X, Zheng S, Thongboonkerd V, Xu M, Pierce WM Jr, Klein JB, Epstein PN (2004) Cardiac mitochondrial damage and biogenesis in a chronic model of type 1 diabetes. Am J Physiol Endocrinol Metab 287:E896–E905
-
(2004)
Am J Physiol Endocrinol Metab
, vol.287
, pp. E896-E905
-
-
Shen, X.1
Zheng, S.2
Thongboonkerd, V.3
Xu, M.4
Pierce, W.M.5
Klein, J.B.6
Epstein, P.N.7
-
116
-
-
34347352169
-
Diabetic cardiomyopathy revisited
-
PID: 17592090
-
Boudina S, Abel ED (2007) Diabetic cardiomyopathy revisited. Circulation 115:3213–3223
-
(2007)
Circulation
, vol.115
, pp. 3213-3223
-
-
Boudina, S.1
Abel, E.D.2
-
117
-
-
84875450015
-
Dissociation of Bcl-2-Beclin1 complex by activated AMPK enhances cardiac autophagy and protects against cardiomyocyte apoptosis in diabetes
-
COI: 1:CAS:528:DC%2BC3sXpvFCku7o%3D, PID: 23223177
-
He C, Zhu H, Li H, Zou MH, Xie Z (2013) Dissociation of Bcl-2-Beclin1 complex by activated AMPK enhances cardiac autophagy and protects against cardiomyocyte apoptosis in diabetes. Diabetes 62:1270–1281
-
(2013)
Diabetes
, vol.62
, pp. 1270-1281
-
-
He, C.1
Zhu, H.2
Li, H.3
Zou, M.H.4
Xie, Z.5
-
118
-
-
79959385996
-
Improvement of cardiac functions by chronic metformin treatment is associated with enhanced cardiac autophagy in diabetic OVE26 mice
-
COI: 1:CAS:528:DC%2BC3MXnvFequr8%3D, PID: 21562078
-
Xie Z, Lau K, Eby B, Lozano P, He C, Pennington B, Li H, Rathi S, Dong Y, Tian R, Kem D, Zou MH (2011) Improvement of cardiac functions by chronic metformin treatment is associated with enhanced cardiac autophagy in diabetic OVE26 mice. Diabetes 60:1770–1778
-
(2011)
Diabetes
, vol.60
, pp. 1770-1778
-
-
Xie, Z.1
Lau, K.2
Eby, B.3
Lozano, P.4
He, C.5
Pennington, B.6
Li, H.7
Rathi, S.8
Dong, Y.9
Tian, R.10
Kem, D.11
Zou, M.H.12
-
119
-
-
0036246990
-
Alcoholic cardiomyopathy: incidence, clinical characteristics, and pathophysiology
-
PID: 12006456
-
Piano MR (2002) Alcoholic cardiomyopathy: incidence, clinical characteristics, and pathophysiology. Chest 121:1638–1650
-
(2002)
Chest
, vol.121
, pp. 1638-1650
-
-
Piano, M.R.1
-
120
-
-
79960323604
-
Deficiency of insulin-like growth factor 1 reduces vulnerability to chronic alcohol intake-induced cardiomyocyte mechanical dysfunction: role of AMPK
-
COI: 1:CAS:528:DC%2BC3MXpsV2hsb8%3D, PID: 20731752
-
Ge W, Li Q, Turdi S, Wang XM, Ren J (2011) Deficiency of insulin-like growth factor 1 reduces vulnerability to chronic alcohol intake-induced cardiomyocyte mechanical dysfunction: role of AMPK. J Cell Mol Med 15:1737–1746
-
(2011)
J Cell Mol Med
, vol.15
, pp. 1737-1746
-
-
Ge, W.1
Li, Q.2
Turdi, S.3
Wang, X.M.4
Ren, J.5
-
121
-
-
84861398110
-
Deficiency in AMPK attenuates ethanol-induced cardiac contractile dysfunction through inhibition of autophagosome formation
-
COI: 1:CAS:528:DC%2BC38Xnt12rtbY%3D, PID: 22451512
-
Guo R, Ren J (2012) Deficiency in AMPK attenuates ethanol-induced cardiac contractile dysfunction through inhibition of autophagosome formation. Cardiovasc Res 94:480–491
-
(2012)
Cardiovasc Res
, vol.94
, pp. 480-491
-
-
Guo, R.1
Ren, J.2
-
122
-
-
84881342673
-
ULK1 plays a critical role in AMPK-mediated myocardial autophagy and contractile dysfunction following acute alcohol challenge
-
COI: 1:CAS:528:DC%2BC3sXht1WgurbE, PID: 23448468
-
Kandadi MR, Hu N, Ren J (2013) ULK1 plays a critical role in AMPK-mediated myocardial autophagy and contractile dysfunction following acute alcohol challenge. Curr Pharm Des 19:4874–4887
-
(2013)
Curr Pharm Des
, vol.19
, pp. 4874-4887
-
-
Kandadi, M.R.1
Hu, N.2
Ren, J.3
-
123
-
-
84877355166
-
Adiponectin knockout accentuates high fat diet-induced obesity and cardiac dysfunction: role of autophagy
-
COI: 1:CAS:528:DC%2BC3sXptV2ku7k%3D, PID: 23524376
-
Guo R, Zhang Y, Turdi S, Ren J (2013) Adiponectin knockout accentuates high fat diet-induced obesity and cardiac dysfunction: role of autophagy. Biochim Biophys Acta 1832:1136–1148
-
(2013)
Biochim Biophys Acta
, vol.1832
, pp. 1136-1148
-
-
Guo, R.1
Zhang, Y.2
Turdi, S.3
Ren, J.4
-
124
-
-
84885125282
-
17-beta Oestradiol prevents cardiovascular dysfunction in post-menopausal metabolic syndrome by affecting SIRT1/AMPK/H3 acetylation
-
COI: 1:CAS:528:DC%2BC3sXhsFOgsL7O, PID: 23826814
-
Bendale DS, Karpe PA, Chhabra R, Shete SP, Shah H, Tikoo K (2013) 17-beta Oestradiol prevents cardiovascular dysfunction in post-menopausal metabolic syndrome by affecting SIRT1/AMPK/H3 acetylation. Br J Pharmacol 170:779–795
-
(2013)
Br J Pharmacol
, vol.170
, pp. 779-795
-
-
Bendale, D.S.1
Karpe, P.A.2
Chhabra, R.3
Shete, S.P.4
Shah, H.5
Tikoo, K.6
-
125
-
-
77951870544
-
Differential AMPK phosphorylation sites associated with phenylephrine vs. antihypertrophic effects of adenosine agonists in neonatal rat ventricular myocytes
-
COI: 1:CAS:528:DC%2BC3cXmt1Kmur4%3D, PID: 20190100
-
Pang T, Rajapurohitam V, Cook MA, Karmazyn M (2010) Differential AMPK phosphorylation sites associated with phenylephrine vs. antihypertrophic effects of adenosine agonists in neonatal rat ventricular myocytes. Am J Physiol Heart Circ Physiol 298:H1382–H1390
-
(2010)
Am J Physiol Heart Circ Physiol
, vol.298
, pp. H1382-H1390
-
-
Pang, T.1
Rajapurohitam, V.2
Cook, M.A.3
Karmazyn, M.4
|