Melatonin reverses flow shear stress-induced injury in bone marrow mesenchymal stem cells via activation of AMP-activated protein kinase signaling

Journal of Pineal Research

Volumn 60, Issue 2, 2016, Pages 228-241

  Yang, Yang ^a,b   Fan, Chongxi ^c   Deng, Chao ^a   Zhao, Lin ^a   Hu, Wei ^b   Di, Shouyin ^c   Ma, Zhiqiang ^c   Zhang, Yu ^a   Qin, Zhigang ^a   Jin, Zhenxiao ^a   Yan, Xiaolong ^c   Jiang, Shuai ^b   Sun, Yang ^a   Yi, Wei ^a  

^a FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^b FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^c FOURTH MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

AMP activated protein kinase; bone marrow mesenchymal stem cells; flow shear stress; melatonin; tissue engineered heart valve

Indexed keywords

ACETYL COENZYME A CARBOXYLASE; CASPASE 3; FIBROBLAST GROWTH FACTOR 2; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; LUZINDOLE; MELATONIN; PLATELET DERIVED GROWTH FACTOR; PROTEIN BAX; PROTEIN BCL 2; PUMA PROTEIN; TRANSFORMING GROWTH FACTOR BETA; VASCULOTROPIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BONE MARROW DERIVED MESENCHYMAL STEM CELL; CELL DAMAGE; CELL VIABILITY; CONTROLLED STUDY; FLOW SHEAR STRESS; FLUORESCENCE ACTIVATED CELL SORTING; HEMATOPOIETIC STEM CELL; IN VITRO STUDY; INFANT; MALE; MOUSE; NONHUMAN; PHASE CONTRAST MICROSCOPY; PROTEIN PHOSPHORYLATION; RAT; SHEAR STRESS; SIGNAL TRANSDUCTION; TISSUE ENGINEERED HEART VALVE; TISSUE ENGINEERING; UPREGULATION; ANIMAL; APOPTOSIS; BONE MARROW CELL; DRUG EFFECTS; ENZYMOLOGY; GENE EXPRESSION REGULATION; MECHANICAL STRESS; MESENCHYMAL STROMA CELL; METABOLISM; PATHOLOGY; PHYSIOLOGICAL STRESS; SPRAGUE DAWLEY RAT;

AMP-ACTIVATED PROTEIN KINASES; ANIMALS; APOPTOSIS; BONE MARROW CELLS; GENE EXPRESSION REGULATION; MALE; MELATONIN; MESENCHYMAL STROMAL CELLS; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION; STRESS, MECHANICAL; STRESS, PHYSIOLOGICAL;

EID: 84957057763     PISSN: 07423098     EISSN: 1600079X     Source Type: Journal    
DOI: 10.1111/jpi.12306     Document Type: Article

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