Resistin promotes cardiac hypertrophy via the AMP-activated protein kinase/mammalian target of rapamycin (AMPK/mTOR) and c-Jun N-terminal kinase/insulin receptor substrate 1 (JNK/IRS1) pathways

Journal of Biological Chemistry

Volumn 286, Issue 21, 2011, Pages 18465-18473

  Kang, Soojeong ^a   Chemaly, Elie R ^a   Hajjar, Roger J ^a   Lebeche, Djamel ^a  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOVIRAL VECTORS; AMP-ACTIVATED PROTEIN KINASE; APOPTOSIS; BRAIN NATRIURETIC PEPTIDE; C-JUN N-TERMINAL KINASE; CARDIAC HYPERTROPHY; CELL SIZE; IN-VITRO; IN-VIVO; INSULIN RECEPTORS; INSULIN RESISTANCE; KINASE TARGETS; LEUCINE INCORPORATION; MARKER GENES; MRNA EXPRESSION; MYOSIN HEAVY CHAIN; N-TERMINALS; NATRIURETIC FACTOR; NEONATAL RAT; OVER-EXPRESSION; PROTEIN SYNTHESIS; RAPAMYCIN; RAT HEART; RECEPTOR SUBSTRATES; RESISTIN; SERINE PHOSPHORYLATION; SIGNALING PATHWAYS; TARGET OF RAPAMYCIN; TUBEROUS SCLEROSIS; VENTRICULAR MYOCYTES;

AMINO ACIDS; ANTIBIOTICS; BIOSYNTHESIS; BRAIN; CELL DEATH; ENZYME ACTIVITY; GENE EXPRESSION; INSULIN; MAMMALS; PATHOLOGY; PHOSPHORYLATION; PROTEINS; TISSUE;

HEART;

HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; INSULIN RECEPTOR SUBSTRATE 1; MAMMALIAN TARGET OF RAPAMYCIN; RESISTIN; STRESS ACTIVATED PROTEIN KINASE;

ANIMAL CELL; APOPTOSIS; ARTICLE; CONTROLLED STUDY; GENE OVEREXPRESSION; HEART VENTRICLE HYPERTROPHY; INSULIN RESISTANCE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS; RAT; SIGNAL TRANSDUCTION; UPREGULATION;

AMP-ACTIVATED PROTEIN KINASES; ANIMALS; APOPTOSIS; BIOLOGICAL MARKERS; CARDIOMEGALY; CELLS, CULTURED; ENZYME INHIBITORS; GENE EXPRESSION REGULATION; INSULIN RECEPTOR SUBSTRATE PROTEINS; INSULIN RESISTANCE; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MYOCYTES, CARDIAC; NATRIURETIC PEPTIDE, BRAIN; PHOSPHORYLATION; RATS; RATS, SPRAGUE-DAWLEY; RESISTIN; RIBOSOMAL PROTEIN S6 KINASES, 70-KDA; SIGNAL TRANSDUCTION; TOR SERINE-THREONINE KINASES; VENTRICULAR MYOSINS;

MAMMALIA; RATTUS;

EID: 79956336867     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.200022     Document Type: Article

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