Knockdown of GSK3β increases basal autophagy and AMPK signalling in nutrient-laden human aortic endothelial cells

Bioscience Reports

Volumn 36, Issue 5, 2016, Pages

  Weikel, Karen A ^a   Cacicedo, Jośe M ^a   Ruderman, Neil B ^a   Ido, Yasuo ^a  

^a BOSTON MEDICAL CENTER   (United States)

Author keywords

AMP Activated protein kinase (AMPK); Autophagy; Endothelium; Forkhead box protein O1 (FOXO1); Glycogen synthase kinase 3 (GSK3 )

Indexed keywords

ADENYLATE KINASE; GLUCOSE; GLYCOGEN SYNTHASE KINASE 3BETA; PALMITIC ACID; PROTEIN KINASE B; TRANSCRIPTION FACTOR FKHR; 6 [[2 [[4 (2,4 DICHLOROPHENYL) 5 (4 METHYL 1H IMIDAZOL 2 YL) 2 PYRIMIDINYL]AMINO]ETHYL]AMINO]NICOTINONITRILE; AMP-ACTIVATED PROTEIN KINASE KINASE; GSK3B PROTEIN, HUMAN; PALMITIC ACID DERIVATIVE; PROTEIN KINASE; PYRIDINE DERIVATIVE; PYRIMIDINE DERIVATIVE;

ACIDIFICATION; ANIMAL TISSUE; AORTIC ENDOTHELIAL CELL; ARTICLE; AUTOPHAGOSOME; AUTOPHAGY; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME REPRESSION; HUMAN; HUMAN CELL; IN VIVO STUDY; INTRACELLULAR SIGNALING; MALE; MOUSE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PROTEIN EXPRESSION; PROTEIN FUNCTION; UPREGULATION; ANIMAL; AORTA; APOPTOSIS; ATHEROSCLEROSIS; BIOSYNTHESIS; ENDOTHELIUM CELL; GENE SILENCING; GENETICS; HYPERGLYCEMIA; METABOLISM; PATHOLOGY; PHOSPHORYLATION; PRIMARY CELL CULTURE; SIGNAL TRANSDUCTION;

ANIMALS; AORTA; APOPTOSIS; ATHEROSCLEROSIS; AUTOPHAGY; DIABETES MELLITUS, TYPE 2; ENDOTHELIAL CELLS; GENE KNOCKDOWN TECHNIQUES; GLUCOSE; GLYCOGEN SYNTHASE KINASE 3 BETA; HUMANS; HYPERGLYCEMIA; MICE; PALMITATES; PHOSPHORYLATION; PRIMARY CELL CULTURE; PROTEIN KINASES; PYRIDINES; PYRIMIDINES; SIGNAL TRANSDUCTION;

EID: 84991677077     PISSN: 01448463     EISSN: 15734935     Source Type: Journal    
DOI: 10.1042/BSR20160174     Document Type: Article

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