-
1
-
-
0031717105
-
The AMP-activated/SNF1 protein kinase subfamily: Metabolic sensors of the eukaryotic cell?
-
D.G. Hardie, D. Carling, and M. Carlson The AMP-activated/SNF1 protein kinase subfamily: metabolic sensors of the eukaryotic cell? Annu. Rev. Biochem. 67 1998 821 855
-
(1998)
Annu. Rev. Biochem.
, vol.67
, pp. 821-855
-
-
Hardie, D.G.1
Carling, D.2
Carlson, M.3
-
2
-
-
0037323971
-
AMP-activated protein kinase, super metabolic regulator
-
B.E. Kemp, D. Stapleton, D.J. Campbell, Z.P. Chen, S. Murthy, M. Walter, A. Gupta, J.J. Adams, F. Katsis, B. van Denderen, I.G. Jennings, T. Iseli, B.J. Michell, and L.A. Witters AMP-activated protein kinase, super metabolic regulator Biochem. Soc. Trans. 31 2003 162 168
-
(2003)
Biochem. Soc. Trans.
, vol.31
, pp. 162-168
-
-
Kemp, B.E.1
Stapleton, D.2
Campbell, D.J.3
Chen, Z.P.4
Murthy, S.5
Walter, M.6
Gupta, A.7
Adams, J.J.8
Katsis, F.9
Van Denderen, B.10
Jennings, I.G.11
Iseli, T.12
Michell, B.J.13
Witters, L.A.14
-
3
-
-
0037328928
-
Malonyl-CoA and AMP-activated protein kinase (AMPK): Possible links between insulin resistance in muscle and early endothelial cell damage in diabetes
-
N.B. Ruderman, J.M. Cacicedo, S. Itani, N. Yagihashi, A.K. Saha, J.M. Ye, K. Chen, M. Zou, D. Carling, G. Boden, R.A. Cohen, J. Keaney, E.W. Kraegen, and Y. Ido Malonyl-CoA and AMP-activated protein kinase (AMPK): possible links between insulin resistance in muscle and early endothelial cell damage in diabetes Biochem. Soc. Trans. 31 2003 202 206
-
(2003)
Biochem. Soc. Trans.
, vol.31
, pp. 202-206
-
-
Ruderman, N.B.1
Cacicedo, J.M.2
Itani, S.3
Yagihashi, N.4
Saha, A.K.5
Ye, J.M.6
Chen, K.7
Zou, M.8
Carling, D.9
Boden, G.10
Cohen, R.A.11
Keaney, J.12
Kraegen, E.W.13
Ido, Y.14
-
4
-
-
0038199737
-
Management of cellular energy by the AMP-activated protein kinase system
-
D.G. Hardie, J.W. Scott, D.A. Pan, and E.R. Hudson Management of cellular energy by the AMP-activated protein kinase system FEBS Lett. 546 2003 113 120
-
(2003)
FEBS Lett.
, vol.546
, pp. 113-120
-
-
Hardie, D.G.1
Scott, J.W.2
Pan, D.A.3
Hudson, E.R.4
-
5
-
-
0035665594
-
Chronic activation of AMP kinase results in NRF-1 activation and mitochondrial biogenesis
-
R. Bergeron, J.M. Ren, K.S. Cadman, I.K. Moore, P. Perret, M. Pypaert, L.H. Young, C.F. Semenkovich, and G.I. Shulman Chronic activation of AMP kinase results in NRF-1 activation and mitochondrial biogenesis Am. J. Physiol. Endocrinol. Metab. 281 2001 E1340 E1346
-
(2001)
Am. J. Physiol. Endocrinol. Metab.
, vol.281
-
-
Bergeron, R.1
Ren, J.M.2
Cadman, K.S.3
Moore, I.K.4
Perret, P.5
Pypaert, M.6
Young, L.H.7
Semenkovich, C.F.8
Shulman, G.I.9
-
6
-
-
2942702297
-
Role of calcium and AMP kinase in the regulation of mitochondrial biogenesis and GLUT4 levels in muscle
-
E.O. Ojuka Role of calcium and AMP kinase in the regulation of mitochondrial biogenesis and GLUT4 levels in muscle Proc. Nutr. Soc. 63 2004 275 278
-
(2004)
Proc. Nutr. Soc.
, vol.63
, pp. 275-278
-
-
Ojuka, E.O.1
-
7
-
-
0037058977
-
AMP kinase is required for mitochondrial biogenesis in skeletal muscle in response to chronic energy deprivation
-
H. Zong, J.M. Ren, L.H. Young, M. Pypaert, J. Mu, M.J. Birnbaum, and G.I. Shulman AMP kinase is required for mitochondrial biogenesis in skeletal muscle in response to chronic energy deprivation Proc. Natl. Acad. Sci. USA 99 2002 15983 15987
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 15983-15987
-
-
Zong, H.1
Ren, J.M.2
Young, L.H.3
Pypaert, M.4
Mu, J.5
Birnbaum, M.J.6
Shulman, G.I.7
-
8
-
-
0042423598
-
Effects of chronic AICAR treatment on fiber composition, enzyme activity, UCP3, and PGC-1 in rat muscles
-
M. Suwa, H. Nakano, and S. Kumagai Effects of chronic AICAR treatment on fiber composition, enzyme activity, UCP3, and PGC-1 in rat muscles J. Appl. Physiol. 95 2003 960 968
-
(2003)
J. Appl. Physiol.
, vol.95
, pp. 960-968
-
-
Suwa, M.1
Nakano, H.2
Kumagai, S.3
-
9
-
-
0036095269
-
Hyperglycemia-induced apoptosis in human umbilical vein endothelial cells: Inhibition by the AMP-activated protein kinase activation
-
Y. Ido, D. Carling, and N. Ruderman Hyperglycemia-induced apoptosis in human umbilical vein endothelial cells: inhibition by the AMP-activated protein kinase activation Diabetes 51 2002 159 167
-
(2002)
Diabetes
, vol.51
, pp. 159-167
-
-
Ido, Y.1
Carling, D.2
Ruderman, N.3
-
11
-
-
0037059549
-
Inhibition of protein kinase Cbeta prevents impaired endothelium- dependent vasodilation caused by hyperglycemia in humans
-
J.A. Beckman, A.B. Goldfine, M.B. Gordon, L.A. Garrett, and M.A. Creager Inhibition of protein kinase Cbeta prevents impaired endothelium-dependent vasodilation caused by hyperglycemia in humans Circ. Res. 90 2002 107 111
-
(2002)
Circ. Res.
, vol.90
, pp. 107-111
-
-
Beckman, J.A.1
Goldfine, A.B.2
Gordon, M.B.3
Garrett, L.A.4
Creager, M.A.5
-
12
-
-
0141730235
-
Diabetes and vascular disease: Pathophysiology, clinical consequences, and medical therapy: Part II
-
T.F. Luscher, M.A. Creager, J.A. Beckman, and F. Cosentino Diabetes and vascular disease: pathophysiology, clinical consequences, and medical therapy: Part II Circulation 108 2003 1655 1661
-
(2003)
Circulation
, vol.108
, pp. 1655-1661
-
-
Luscher, T.F.1
Creager, M.A.2
Beckman, J.A.3
Cosentino, F.4
-
13
-
-
0141615827
-
Diabetes and vascular disease: Pathophysiology, clinical consequences, and medical therapy: Part I
-
M.A. Creager, T.F. Luscher, F. Cosentino, and J.A. Beckman Diabetes and vascular disease: pathophysiology, clinical consequences, and medical therapy: Part I Circulation 108 2003 1527 1532
-
(2003)
Circulation
, vol.108
, pp. 1527-1532
-
-
Creager, M.A.1
Luscher, T.F.2
Cosentino, F.3
Beckman, J.A.4
-
14
-
-
0034746311
-
NF-kappaB: Pivotal mediator or innocent bystander in atherogenesis?
-
T. Collins, and M.I. Cybulsky NF-kappaB: pivotal mediator or innocent bystander in atherogenesis? J. Clin. Invest. 107 2001 255 264
-
(2001)
J. Clin. Invest.
, vol.107
, pp. 255-264
-
-
Collins, T.1
Cybulsky, M.I.2
-
15
-
-
0037180771
-
Inflammation in atherosclerosis
-
P. Libby Inflammation in atherosclerosis Nature 420 2002 868 874
-
(2002)
Nature
, vol.420
, pp. 868-874
-
-
Libby, P.1
-
16
-
-
0842277242
-
Definition of metabolic syndrome: Report of the National Heart, Lung, and Blood Institute/American Heart Association conference on scientific issues related to definition
-
S.M. Grundy, H.B. Brewer Jr., J.I. Cleeman, S.C. Smith Jr., and C. Lenfant Definition of metabolic syndrome: report of the National Heart, Lung, and Blood Institute/American Heart Association conference on scientific issues related to definition Circulation 109 2004 433 438
-
(2004)
Circulation
, vol.109
, pp. 433-438
-
-
Grundy, S.M.1
Brewer Jr., H.B.2
Cleeman, J.I.3
Smith Jr., S.C.4
Lenfant, C.5
-
17
-
-
0242559050
-
Prevention of type 2 diabetes and its macrovascular complications: Whom, when, and how should we treat?
-
C. Panzer, A. Brieke, and N.B. Ruderman Prevention of type 2 diabetes and its macrovascular complications: whom, when, and how should we treat? Curr. Opi. Endocrinol. Diab. 10 2003 229 236
-
(2003)
Curr. Opi. Endocrinol. Diab.
, vol.10
, pp. 229-236
-
-
Panzer, C.1
Brieke, A.2
Ruderman, N.B.3
-
18
-
-
0036134744
-
Unsaturated fatty acids selectively induce an inflammatory environment in human endothelial cells
-
M. Toborek, Y.W. Lee, R. Garrido, S. Kaiser, and B. Hennig Unsaturated fatty acids selectively induce an inflammatory environment in human endothelial cells Am. J. Clin. Nutr. 75 2002 119 125
-
(2002)
Am. J. Clin. Nutr.
, vol.75
, pp. 119-125
-
-
Toborek, M.1
Lee, Y.W.2
Garrido, R.3
Kaiser, S.4
Hennig, B.5
-
19
-
-
0036300538
-
Lipid-induced insulin resistance in human muscle is associated with changes in diacylglycerol, protein kinase C, and IkappaB-alpha
-
S.I. Itani, N.B. Ruderman, F. Schmieder, and G. Boden Lipid-induced insulin resistance in human muscle is associated with changes in diacylglycerol, protein kinase C, and IkappaB-alpha Diabetes 51 2002 2005 2011
-
(2002)
Diabetes
, vol.51
, pp. 2005-2011
-
-
Itani, S.I.1
Ruderman, N.B.2
Schmieder, F.3
Boden, G.4
-
20
-
-
0035656173
-
Diabetes-associated sustained activation of the transcription factor nuclear factor-kappaB
-
A. Bierhaus, S. Schiekofer, M. Schwaninger, M. Andrassy, P.M. Humpert, J. Chen, M. Hong, T. Luther, T. Henle, I. Kloting, M. Morcos, M. Hofmann, H. Tritschler, B. Weigle, M. Kasper, M. Smith, G. Perry, A.M. Schmidt, D.M. Stern, H.U. Haring, E. Schleicher, and P.P. Nawroth Diabetes-associated sustained activation of the transcription factor nuclear factor-kappaB Diabetes 50 2001 2792 2808
-
(2001)
Diabetes
, vol.50
, pp. 2792-2808
-
-
Bierhaus, A.1
Schiekofer, S.2
Schwaninger, M.3
Andrassy, M.4
Humpert, P.M.5
Chen, J.6
Hong, M.7
Luther, T.8
Henle, T.9
Kloting, I.10
Morcos, M.11
Hofmann, M.12
Tritschler, H.13
Weigle, B.14
Kasper, M.15
Smith, M.16
Perry, G.17
Schmidt, A.M.18
Stern, D.M.19
Haring, H.U.20
Schleicher, E.21
Nawroth, P.P.22
more..
-
21
-
-
0014216041
-
Removal of fatty acids from serum albumin by charcoal treatment
-
R.F. Chen Removal of fatty acids from serum albumin by charcoal treatment J. Biol. Chem. 242 1967 173 181
-
(1967)
J. Biol. Chem.
, vol.242
, pp. 173-181
-
-
Chen, R.F.1
-
22
-
-
0031784544
-
Tumor necrosis factor-alpha in sera of obese patients: Fall with weight loss
-
P. Dandona, R. Weinstock, K. Thusu, E. Abdel-Rahman, A. Aljada, and T. Wadden Tumor necrosis factor-alpha in sera of obese patients: fall with weight loss J. Clin. Endocrinol. Metab. 83 1998 2907 2910
-
(1998)
J. Clin. Endocrinol. Metab.
, vol.83
, pp. 2907-2910
-
-
Dandona, P.1
Weinstock, R.2
Thusu, K.3
Abdel-Rahman, E.4
Aljada, A.5
Wadden, T.6
-
23
-
-
2642561229
-
Palmitate, but not unsaturated fatty acids, induces the expression of interleukin-6 in human myotubes through proteasome-dependent activation of nuclear factor-kappaB
-
C. Weigert, K. Brodbeck, H. Staiger, C. Kausch, F. Machicao, H.U. Haring, and E.D. Schleicher Palmitate, but not unsaturated fatty acids, induces the expression of interleukin-6 in human myotubes through proteasome-dependent activation of nuclear factor-kappaB J. Biol. Chem. 279 2004 23942 23952
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 23942-23952
-
-
Weigert, C.1
Brodbeck, K.2
Staiger, H.3
Kausch, C.4
MacHicao, F.5
Haring, H.U.6
Schleicher, E.D.7
-
24
-
-
0035527486
-
Linoleic acid-induced VCAM-1 expression in human microvascular endothelial cells is mediated by the NF-kappa B-dependent pathway
-
H.J. Park, Y.W. Lee, B. Hennig, and M. Toborek Linoleic acid-induced VCAM-1 expression in human microvascular endothelial cells is mediated by the NF-kappa B-dependent pathway Nutr. Cancer 41 2001 126 134
-
(2001)
Nutr. Cancer
, vol.41
, pp. 126-134
-
-
Park, H.J.1
Lee, Y.W.2
Hennig, B.3
Toborek, M.4
-
25
-
-
3843061592
-
AMP kinase and malonyl CoA: Targets for therapy of the metabolic syndrome
-
N.R. Ruderman, and M. Prentki AMP kinase and malonyl CoA: targets for therapy of the metabolic syndrome Nat. Rev. Drug Discov. 3 2004 1 13
-
(2004)
Nat. Rev. Drug Discov.
, vol.3
, pp. 1-13
-
-
Ruderman, N.R.1
Prentki, M.2
-
26
-
-
0013375847
-
AMP-kinase activation prevents TNF-alpha induced ICAM expression by inhibiting NF-kB transactivation but not by inhibiting their translocation or DNA-binding
-
Y. Ido, N. Yagihashi, J.M. Cacicedo, and N.R. Ruderman AMP-kinase activation prevents TNF-alpha induced ICAM expression by inhibiting NF-kB transactivation but not by inhibiting their translocation or DNA-binding Diabetes 51 2002 A458
-
(2002)
Diabetes
, vol.51
, pp. 458
-
-
Ido, Y.1
Yagihashi, N.2
Cacicedo, J.M.3
Ruderman, N.R.4
-
27
-
-
0037432309
-
Allograft arteriosclerosis and immune-driven angiogenesis
-
P. Libby, and D.X. Zhao Allograft arteriosclerosis and immune-driven angiogenesis Circulation 107 2003 1237 1239
-
(2003)
Circulation
, vol.107
, pp. 1237-1239
-
-
Libby, P.1
Zhao, D.X.2
-
28
-
-
20044367868
-
The Metabolic syndrome
-
L. DeGroot J. Jameson Elsevier Philadelphia
-
N. Ruderman, and G. Shulman The Metabolic syndrome L. DeGroot J. Jameson Endocrinology 2004 Elsevier Philadelphia Chapter 61
-
(2004)
Endocrinology
-
-
Ruderman, N.1
Shulman, G.2
-
29
-
-
14344262402
-
Free fatty acid-induced hepatic insulin resistance: Evidence for a protein kinase C (PKC)-delta, oxidative stress and IKKbeta (Inhibitor of NF-kappaB) signaling pathway
-
P. Han, U. Toyoyoshi, A.C. Haber, T.K. Lam, L. Stavar, C. Tang, G.I. Fantus, and A. Giacca Free fatty acid-induced hepatic insulin resistance: evidence for a protein kinase C (PKC)-delta, oxidative stress and IKKbeta (Inhibitor of NF-kappaB) signaling pathway Diabetes 53 2004 A48
-
(2004)
Diabetes
, vol.53
, pp. 48
-
-
Han, P.1
Toyoyoshi, U.2
Haber, A.C.3
Lam, T.K.4
Stavar, L.5
Tang, C.6
Fantus, G.I.7
Giacca, A.8
-
30
-
-
0035856980
-
Biochemistry and molecular cell biology of diabetic complications
-
M. Brownlee Biochemistry and molecular cell biology of diabetic complications Nature 414 2001 813 820
-
(2001)
Nature
, vol.414
, pp. 813-820
-
-
Brownlee, M.1
-
32
-
-
0030667807
-
Activation of nuclear factor-kappaB in cultured endothelial cells by increased glucose concentration: Prevention by calphostin C
-
G.M. Pieper, and H. Riaz ul Activation of nuclear factor-kappaB in cultured endothelial cells by increased glucose concentration: prevention by calphostin C J. Cardiovasc. Pharmacol. 30 1997 528 532
-
(1997)
J. Cardiovasc. Pharmacol.
, vol.30
, pp. 528-532
-
-
Pieper, G.M.1
Riaz Ul, H.2
-
33
-
-
0034643340
-
Normalizing mitochondrial superoxide production blocks three pathways of hyperglycaemic damage
-
T. Nishikawa, D. Edelstein, X.L. Du, S. Yamagishi, T. Matsumura, Y. Kaneda, M.A. Yorek, D. Beebe, P.J. Oates, H.P. Hammes, I. Giardino, and M. Brownlee Normalizing mitochondrial superoxide production blocks three pathways of hyperglycaemic damage Nature 404 2000 787 790
-
(2000)
Nature
, vol.404
, pp. 787-790
-
-
Nishikawa, T.1
Edelstein, D.2
Du, X.L.3
Yamagishi, S.4
Matsumura, T.5
Kaneda, Y.6
Yorek, M.A.7
Beebe, D.8
Oates, P.J.9
Hammes, H.P.10
Giardino, I.11
Brownlee, M.12
-
34
-
-
0344850195
-
Generation of reactive oxygen intermediates, activation of NF-kappaB, and induction of apoptosis in human endothelial cells by glucose: Role of nitric oxide synthase?
-
X. Du, K. Stocklauser-Farber, and P. Rosen Generation of reactive oxygen intermediates, activation of NF-kappaB, and induction of apoptosis in human endothelial cells by glucose: role of nitric oxide synthase? Free Radic. Biol. Med. 27 1999 752 763
-
(1999)
Free Radic. Biol. Med.
, vol.27
, pp. 752-763
-
-
Du, X.1
Stocklauser-Farber, K.2
Rosen, P.3
-
35
-
-
2442631329
-
Advanced glycation end product-induced activation of NF-kappaB is suppressed by alpha-lipoic acid in cultured endothelial cells
-
A. Bierhaus, S. Chevion, M. Chevion, M. Hofmann, P. Quehenberger, T. Illmer, T. Luther, E. Berentshtein, H. Tritschler, M. Muller, P. Wahl, R. Ziegler, and P.P. Nawroth Advanced glycation end product-induced activation of NF-kappaB is suppressed by alpha-lipoic acid in cultured endothelial cells Diabetes 46 1997 1481 1490
-
(1997)
Diabetes
, vol.46
, pp. 1481-1490
-
-
Bierhaus, A.1
Chevion, S.2
Chevion, M.3
Hofmann, M.4
Quehenberger, P.5
Illmer, T.6
Luther, T.7
Berentshtein, E.8
Tritschler, H.9
Muller, M.10
Wahl, P.11
Ziegler, R.12
Nawroth, P.P.13
-
36
-
-
0242298211
-
Increased NF-kappaB DNA binding but not transcriptional activity during apoptosis induced by the COX-2-selective inhibitor NS-398 in colorectal carcinoma cells
-
H.J. Smartt, D.J. Elder, D.J. Hicks, N.A. Williams, and C. Paraskeva Increased NF-kappaB DNA binding but not transcriptional activity during apoptosis induced by the COX-2-selective inhibitor NS-398 in colorectal carcinoma cells Br. J. Cancer 89 2003 1358 1365
-
(2003)
Br. J. Cancer
, vol.89
, pp. 1358-1365
-
-
Smartt, H.J.1
Elder, D.J.2
Hicks, D.J.3
Williams, N.A.4
Paraskeva, C.5
-
37
-
-
0029088742
-
Advanced glycation endproducts interacting with their endothelial receptor induce expression of vascular cell adhesion molecule-1 (VCAM-1) in cultured human endothelial cells and in mice. a potential mechanism for the accelerated vasculopathy of diabetes
-
A.M. Schmidt, O. Hori, J.X. Chen, J.F. Li, J. Crandall, J. Zhang, R. Cao, S.D. Yan, J. Brett, and D. Stern Advanced glycation endproducts interacting with their endothelial receptor induce expression of vascular cell adhesion molecule-1 (VCAM-1) in cultured human endothelial cells and in mice. A potential mechanism for the accelerated vasculopathy of diabetes J. Clin. Invest. 96 1995 1395 1403
-
(1995)
J. Clin. Invest.
, vol.96
, pp. 1395-1403
-
-
Schmidt, A.M.1
Hori, O.2
Chen, J.X.3
Li, J.F.4
Crandall, J.5
Zhang, J.6
Cao, R.7
Yan, S.D.8
Brett, J.9
Stern, D.10
-
38
-
-
0029882671
-
RAGE: A novel cellular receptor for advanced glycation end products
-
A.M. Schmidt, O. Hori, R. Cao, S.D. Yan, J. Brett, J.L. Wautier, S. Ogawa, K. Kuwabara, M. Matsumoto, and D. Stern RAGE: a novel cellular receptor for advanced glycation end products Diabetes 45 Suppl. 3 1996 S77 80
-
(1996)
Diabetes
, vol.45
, Issue.SUPPL. 3
, pp. 77-80
-
-
Schmidt, A.M.1
Hori, O.2
Cao, R.3
Yan, S.D.4
Brett, J.5
Wautier, J.L.6
Ogawa, S.7
Kuwabara, K.8
Matsumoto, M.9
Stern, D.10
-
39
-
-
0035933369
-
Acute regulation of fatty acid oxidation and amp-activated protein kinase in human umbilical vein endothelial cells
-
Z. Dagher, N. Ruderman, K. Tornheim, and Y. Ido Acute regulation of fatty acid oxidation and amp-activated protein kinase in human umbilical vein endothelial cells Circ. Res. 88 2001 1276 1282
-
(2001)
Circ. Res.
, vol.88
, pp. 1276-1282
-
-
Dagher, Z.1
Ruderman, N.2
Tornheim, K.3
Ido, Y.4
|