Unraveling the actions of AMP-activated protein kinase in metabolic diseases: Systemic to molecular insights

Metabolism: Clinical and Experimental

Volumn 65, Issue 5, 2016, Pages 634-645

  Weikel, Karen A ^a   Ruderman, Neil B ^a   Cacicedo, José M ^a  

^a BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

AMPK; Insulin resistance; Lysosome; mTORC1; Type 2 diabetes

Indexed keywords

ACETYL COENZYME A CARBOXYLASE; ADIPONECTIN; AXIN; GLUCOSE; GLYCEROL 3 PHOSPHATE ACYLTRANSFERASE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; INSULIN; LEPTIN; MALONYL COENZYME A; MALONYL COENZYME A DECARBOXYLASE; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 1; METFORMIN; STEROL REGULATORY ELEMENT BINDING PROTEIN 1; STEROL REGULATORY ELEMENT BINDING PROTEIN 1C; STEROL REGULATORY ELEMENT BINDING PROTEIN 2; MECHANISTIC TARGET OF RAPAMYCIN COMPLEX 1; MULTIPROTEIN COMPLEX; TARGET OF RAPAMYCIN KINASE; TUMOR PROTEIN;

ADIPOSE TISSUE; AUTOPHAGY; CELL ENERGY; CYTOKINE RELEASE; ENDOTHELIUM; ENZYME ACTIVATION; ENZYME ACTIVE SITE; ENZYME BINDING; ENZYME PHOSPHORYLATION; FATTY ACID OXIDATION; GENE EXPRESSION; GLUCONEOGENESIS; GLUCOSE TRANSPORT; HOMEOSTASIS; HUMAN; INSULIN RESISTANCE; INSULIN SENSITIVITY; LIPID STORAGE; LIPOLYSIS; LYSOSOME MEMBRANE; MACROPHAGE ACTIVATION; METABOLIC DISORDER; MITOCHONDRIAL BIOGENESIS; MOLECULAR INTERACTION; NEGATIVE FEEDBACK; NEOPLASM; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; NUTRIENT AVAILABILITY; OBESITY; OVERNUTRITION; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN SYNTHESIS; REGULATORY MECHANISM; REVIEW; SKELETAL MUSCLE; SYSTEMIC THERAPY; ANIMAL; ANTIBODY SPECIFICITY; BIOLOGICAL MODEL; CALORIC INTAKE; CHEMISTRY; DISORDERS OF CARBOHYDRATE METABOLISM; ENERGY METABOLISM; ENZYMOLOGY; LYSOSOME; METABOLISM;

AMP-ACTIVATED PROTEIN KINASES; ANIMALS; ENERGY INTAKE; ENERGY METABOLISM; GLUCOSE METABOLISM DISORDERS; HUMANS; INSULIN RESISTANCE; LYSOSOMES; MODELS, BIOLOGICAL; MULTIPROTEIN COMPLEXES; NEOPLASM PROTEINS; NEOPLASMS; OBESITY; ORGAN SPECIFICITY; TOR SERINE-THREONINE KINASES;

EID: 84962018712     PISSN: 00260495     EISSN: 15328600     Source Type: Journal    
DOI: 10.1016/j.metabol.2016.01.005     Document Type: Review

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