Lysosomal ceramide generated by acid sphingomyelinase triggers cytosolic cathepsin B-mediated degradation of X-linked inhibitor of apoptosis protein in natural killer/T lymphoma cell apoptosis

Cell Death and Disease

Volumn 6, Issue 4, 2015, Pages

  Taniguchi, M ^a   Ogiso, H ^a   Takeuchi, T ^a   Kitatani, K ^b   Umehara, H ^c   Okazaki, T ^a  

^a KANAZAWA MEDICAL UNIVERSITY   (Japan)

^b TOHOKU UNIVERSITY   (Japan)

^c KYOTO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 3; CASPASE 8; CASPASE 9; CERAMIDE; DESIPRAMINE; INTERLEUKIN 2; SPHINGOMYELIN PHOSPHODIESTERASE; X LINKED INHIBITOR OF APOPTOSIS; CATHEPSIN B; CTSB PROTEIN, HUMAN; XIAP PROTEIN, HUMAN;

APOPTOSIS; ARTICLE; CONTROLLED STUDY; CYTOSOL; ENZYME ACTIVATION; HUMAN; HUMAN CELL; LYMPHOMA CELL; LYSOSOME; NATURAL KILLER T CELL; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN SECRETION; SIGNAL TRANSDUCTION; BIOSYNTHESIS; DEFICIENCY; METABOLISM; NATURAL KILLER CELL; PATHOLOGY; PHYSIOLOGY; T CELL LYMPHOMA; TUMOR CELL LINE;

APOPTOSIS; CASPASE 3; CATHEPSIN B; CELL LINE, TUMOR; CERAMIDES; CYTOSOL; HUMANS; INTERLEUKIN-2; KILLER CELLS, NATURAL; LYMPHOMA, T-CELL; LYSOSOMES; SPHINGOMYELIN PHOSPHODIESTERASE; X-LINKED INHIBITOR OF APOPTOSIS PROTEIN;

EID: 84989350484     PISSN: None     EISSN: 20414889     Source Type: Journal    
DOI: 10.1038/cddis.2015.82     Document Type: Article

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