-
1
-
-
80355143546
-
Microglial cell origin and phenotypes in health and disease
-
Saijo K, Glass CK. Microglial cell origin and phenotypes in health and disease. Nat Rev Immunol 2011; 11: 775-787.
-
(2011)
Nat Rev Immunol
, vol.11
, pp. 775-787
-
-
Saijo, K.1
Glass, C.K.2
-
2
-
-
33845768784
-
Microglia-mediated neurotoxicity: Uncovering the molecular mechanisms
-
Block ML, Zecca L, Hong JS. Microglia-mediated neurotoxicity: uncovering the molecular mechanisms. Nat Rev Neurosci 2007; 8: 57-69.
-
(2007)
Nat Rev Neurosci
, vol.8
, pp. 57-69
-
-
Block, M.L.1
Zecca, L.2
Hong, J.S.3
-
4
-
-
0023789193
-
Reactive microglia are positive for HLA-DR in the substantia nigra of Parkinson's and Alzheimer's disease brains
-
McGeer PL, Itagaki S, Boyes BE, McGeer EG. Reactive microglia are positive for HLA-DR in the substantia nigra of Parkinson's and Alzheimer's disease brains. Neurology 1988; 38: 1285-1291.
-
(1988)
Neurology
, vol.38
, pp. 1285-1291
-
-
McGeer, P.L.1
Itagaki, S.2
Boyes, B.E.3
McGeer, E.G.4
-
5
-
-
79955485064
-
Caspase signalling controls microglia activation and neurotoxicity
-
Burguillos MA, Deierborg T, Kavanagh E, Persson A, Hajji N, Garcia-Quintanilla A et al. Caspase signalling controls microglia activation and neurotoxicity. Nature 2011; 472: 319-324.
-
(2011)
Nature
, vol.472
, pp. 319-324
-
-
Burguillos, M.A.1
Deierborg, T.2
Kavanagh, E.3
Persson, A.4
Hajji, N.5
Garcia-Quintanilla, A.6
-
6
-
-
0035942505
-
Defective caspase-3 relocalization in non-small cell lung carcinoma
-
Joseph B, Ekedahl J, Lewensohn R, Marchetti P, Formstecher P, Zhivotovsky B. Defective caspase-3 relocalization in non-small cell lung carcinoma. Oncogene 2001; 20: 2877-2888.
-
(2001)
Oncogene
, vol.20
, pp. 2877-2888
-
-
Joseph, B.1
Ekedahl, J.2
Lewensohn, R.3
Marchetti, P.4
Formstecher, P.5
Zhivotovsky, B.6
-
7
-
-
0030976895
-
A sequential two-step mechanism for the production of the mature p17:p12 form of caspase-3 in vitro
-
Han Z, Hendrickson EA, Bremner TA, Wyche JH. A sequential two-step mechanism for the production of the mature p17:p12 form of caspase-3 in vitro. J Biol Chem 1997; 272: 13432-13436.
-
(1997)
J Biol Chem
, vol.272
, pp. 13432-13436
-
-
Han, Z.1
Hendrickson, E.A.2
Bremner, T.A.3
Wyche, J.H.4
-
8
-
-
0031881687
-
Lipopolysaccharide intranigral injection induces inflammatory reaction and damage in nigrostriatal dopaminergic system
-
Castano A, Herrera AJ, Cano J, Machado A. Lipopolysaccharide intranigral injection induces inflammatory reaction and damage in nigrostriatal dopaminergic system. J Neurochem 1998; 70: 1584-1592.
-
(1998)
J Neurochem
, vol.70
, pp. 1584-1592
-
-
Castano, A.1
Herrera, A.J.2
Cano, J.3
MacHado, A.4
-
9
-
-
63049083734
-
A Nurr1/CoREST pathway in microglia and astrocytes protects dopaminergic neurons from inflammation-induced death
-
Saijo K, Winner B, Carson CT, Collier JG, Boyer L, Rosenfeld MG et al. A Nurr1/CoREST pathway in microglia and astrocytes protects dopaminergic neurons from inflammation-induced death. Cell 2009; 137: 47-59.
-
(2009)
Cell
, vol.137
, pp. 47-59
-
-
Saijo, K.1
Winner, B.2
Carson, C.T.3
Collier, J.G.4
Boyer, L.5
Rosenfeld, M.G.6
-
10
-
-
12544256390
-
Nuclear translocation of caspase-3 is dependent on its proteolytic activation and recognition of a substrate-like protein(s)
-
Kamada S, Kikkawa U, Tsujimoto Y, Hunter T. Nuclear translocation of caspase-3 is dependent on its proteolytic activation and recognition of a substrate-like protein(s). J Biol Chem 2005; 280: 857-860.
-
(2005)
J Biol Chem
, vol.280
, pp. 857-860
-
-
Kamada, S.1
Kikkawa, U.2
Tsujimoto, Y.3
Hunter, T.4
-
11
-
-
76449100488
-
Nuclear entry of active caspase-3 is facilitated by its p3-recognition-based specific cleavage activity
-
Luo M, Lu Z, Sun H, Yuan K, Zhang Q, Meng S et al. Nuclear entry of active caspase-3 is facilitated by its p3-recognition-based specific cleavage activity. Cell Res 2010; 20: 211-222.
-
(2010)
Cell Res
, vol.20
, pp. 211-222
-
-
Luo, M.1
Lu, Z.2
Sun, H.3
Yuan, K.4
Zhang, Q.5
Meng, S.6
-
12
-
-
34548305137
-
Binding of caspase-3 prodomain to heat shock protein 27 regulates monocyte apoptosis by inhibiting caspase-3 proteolytic activation
-
Voss OH, Batra S, Kolattukudy SJ, Gonzalez-Mejia ME, Smith JB, Doseff AI. Binding of caspase-3 prodomain to heat shock protein 27 regulates monocyte apoptosis by inhibiting caspase-3 proteolytic activation. J Biol Chem 2007; 282: 25088-25099.
-
(2007)
J Biol Chem
, vol.282
, pp. 25088-25099
-
-
Voss, O.H.1
Batra, S.2
Kolattukudy, S.J.3
Gonzalez-Mejia, M.E.4
Smith, J.B.5
Doseff, A.I.6
-
13
-
-
84875138006
-
Inhibitor of apoptosis (IAP) proteins-modulators of cell death and inflammation
-
Silke J, Meier P. Inhibitor of apoptosis (IAP) proteins-modulators of cell death and inflammation. Cold Spring Harb Perspect Biol 2013; 5.
-
(2013)
Cold Spring Harb Perspect Biol
, pp. 5
-
-
Silke, J.1
Meier, P.2
-
14
-
-
77954930632
-
IAPs: From caspase inhibitors to modulators of NF-kappa B, inflammation and cancer
-
Gyrd-Hansen M, Meier P. IAPs: from caspase inhibitors to modulators of NF-kappa B, inflammation and cancer. Nat Rev Cancer 2010; 10: 561-574.
-
(2010)
Nat Rev Cancer
, vol.10
, pp. 561-574
-
-
Gyrd-Hansen, M.1
Meier, P.2
-
15
-
-
12344300349
-
IAPs are functionally non-equivalent and regulate effector caspases through distinct mechanisms
-
Tenev T, Zachariou A, Wilson R, Ditzel M, Meier P. IAPs are functionally non-equivalent and regulate effector caspases through distinct mechanisms. Nat Cell Biol 2005; 7: 70-77.
-
(2005)
Nat Cell Biol
, vol.7
, pp. 70-77
-
-
Tenev, T.1
Zachariou, A.2
Wilson, R.3
Ditzel, M.4
Meier, P.5
-
16
-
-
33645640920
-
The human anti-apoptotic proteins cIAP1 and cIAP2 bind but do not inhibit caspases
-
Eckelman BP, Salvesen GS. The human anti-apoptotic proteins cIAP1 and cIAP2 bind but do not inhibit caspases. J Biol Chem 2006; 281: 3254-3260.
-
(2006)
J Biol Chem
, vol.281
, pp. 3254-3260
-
-
Eckelman, B.P.1
Salvesen, G.S.2
-
17
-
-
77956932246
-
CIAP1 cooperatively inhibits procaspase-3 activation by the caspase-9 apoptosome
-
Burke SP, Smith L, Smith JB. cIAP1 cooperatively inhibits procaspase-3 activation by the caspase-9 apoptosome. J Biol Chem 2010; 285: 30061-30068.
-
(2010)
J Biol Chem
, vol.285
, pp. 30061-30068
-
-
Burke, S.P.1
Smith, L.2
Smith, J.B.3
-
18
-
-
0034672626
-
Lipopolysaccharide induces the expression of cellular inhibitor of apoptosis protein-2 in human macrophages
-
Cui X, Imaizumi T, Yoshida H, Tanji K, Matsumiya T, Satoh K. Lipopolysaccharide induces the expression of cellular inhibitor of apoptosis protein-2 in human macrophages. Biochim Biophys Acta 2000; 1524: 178-182.
-
(2000)
Biochim Biophys Acta
, vol.1524
, pp. 178-182
-
-
Cui, X.1
Imaizumi, T.2
Yoshida, H.3
Tanji, K.4
Matsumiya, T.5
Satoh, K.6
-
19
-
-
30744452261
-
Inhibitor of apoptosis protein cIAP2 is essential for lipopolysaccharide-induced macrophage survival
-
Conte D, Holcik M, Lefebvre CA, Lacasse E, Picketts DJ, Wright KE et al. Inhibitor of apoptosis protein cIAP2 is essential for lipopolysaccharide-induced macrophage survival. Mol Cell Biol 2006; 26: 699-708.
-
(2006)
Mol Cell Biol
, vol.26
, pp. 699-708
-
-
Conte, D.1
Holcik, M.2
Lefebvre, C.A.3
Lacasse, E.4
Picketts, D.J.5
Wright, K.E.6
-
20
-
-
0034282432
-
The inhibitor of apoptosis, cIAP2, functions as a ubiquitin-protein ligase and promotes in vitro monoubiquitination of caspases 3 and 7
-
Huang H, Joazeiro CA, Bonfoco E, Kamada S, Leverson JD, Hunter T. The inhibitor of apoptosis, cIAP2, functions as a ubiquitin-protein ligase and promotes in vitro monoubiquitination of caspases 3 and 7. J Biol Chem 2000; 275: 26661-26664.
-
(2000)
J Biol Chem
, vol.275
, pp. 26661-26664
-
-
Huang, H.1
Joazeiro, C.A.2
Bonfoco, E.3
Kamada, S.4
Leverson, J.D.5
Hunter, T.6
-
21
-
-
32044442717
-
CIAP2 is highly expressed in Hodgkin-Reed-Sternberg cells and inhibits apoptosis by interfering with constitutively active caspase-3
-
Durkop H, Hirsch B, Hahn C, Stein H. cIAP2 is highly expressed in Hodgkin-Reed-Sternberg cells and inhibits apoptosis by interfering with constitutively active caspase-3. J Mol Med (Berl) 2006; 84: 132-141.
-
(2006)
J Mol Med (Berl)
, vol.84
, pp. 132-141
-
-
Durkop, H.1
Hirsch, B.2
Hahn, C.3
Stein, H.4
-
22
-
-
33750485792
-
IAP-IAP complexes required for apoptosis resistance of C. Trachomatis-infected cells
-
Rajalingam K, Sharma M, Paland N, Hurwitz R, Thieck O, Oswald M et al. IAP-IAP complexes required for apoptosis resistance of C. trachomatis-infected cells. PLoS Pathog 2006; 2: e114.
-
(2006)
PLoS Pathog
, vol.2
, pp. e114
-
-
Rajalingam, K.1
Sharma, M.2
Paland, N.3
Hurwitz, R.4
Thieck, O.5
Oswald, M.6
-
23
-
-
0034616945
-
Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition
-
Du C, Fang M, Li Y, Li L, Wang X. Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition. Cell 2000; 102: 33-42.
-
(2000)
Cell
, vol.102
, pp. 33-42
-
-
Du, C.1
Fang, M.2
Li, Y.3
Li, L.4
Wang, X.5
-
24
-
-
0034616942
-
Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins
-
Verhagen AM, Ekert PG, Pakusch M, Silke J, Connolly LM, Reid GE et al. Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins. Cell 2000; 102: 43-53.
-
(2000)
Cell
, vol.102
, pp. 43-53
-
-
Verhagen, A.M.1
Ekert, P.G.2
Pakusch, M.3
Silke, J.4
Connolly, L.M.5
Reid, G.E.6
-
25
-
-
36048999753
-
IAP antagonists induce autoubiquitination of c-IAPs, NF-kappaB activation, and TNFalpha-dependent apoptosis
-
Varfolomeev E, Blankenship JW, Wayson SM, Fedorova AV, Kayagaki N, Garg P et al. IAP antagonists induce autoubiquitination of c-IAPs, NF-kappaB activation, and TNFalpha-dependent apoptosis. Cell 2007; 131: 669-681.
-
(2007)
Cell
, vol.131
, pp. 669-681
-
-
Varfolomeev, E.1
Blankenship, J.W.2
Wayson, S.M.3
Fedorova, A.V.4
Kayagaki, N.5
Garg, P.6
-
26
-
-
36148954336
-
IAP antagonists target cIAP1 to induce TNFalpha-dependent apoptosis
-
Vince JE, Wong WW, Khan N, Feltham R, Chau D, Ahmed AU et al. IAP antagonists target cIAP1 to induce TNFalpha-dependent apoptosis. Cell 2007; 131: 682-693.
-
(2007)
Cell
, vol.131
, pp. 682-693
-
-
Vince, J.E.1
Wong, W.W.2
Khan, N.3
Feltham, R.4
Chau, D.5
Ahmed, A.U.6
-
27
-
-
79959738733
-
SMAC mimetic BV6 induces cell death in monocytes and maturation of monocyte-derived dendritic cells
-
Muller-Sienerth N, Dietz L, Holtz P, Kapp M, Grigoleit GU, Schmuck C et al. SMAC mimetic BV6 induces cell death in monocytes and maturation of monocyte-derived dendritic cells. PloS One 2011; 6: e21556.
-
(2011)
PloS One
, vol.6
, pp. e21556
-
-
Muller-Sienerth, N.1
Dietz, L.2
Holtz, P.3
Kapp, M.4
Grigoleit, G.U.5
Schmuck, C.6
-
28
-
-
0029068871
-
Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis
-
Nicholson DW, Ali A, Thornberry NA, Vaillancourt JP, Ding CK, Gallant M et al. Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis. Nature 1995; 376: 37-43.
-
(1995)
Nature
, vol.376
, pp. 37-43
-
-
Nicholson, D.W.1
Ali, A.2
Thornberry, N.A.3
Vaillancourt, J.P.4
Ding, C.K.5
Gallant, M.6
-
30
-
-
84893825107
-
Smac mimetics and innate immune stimuli synergize to promote tumor death
-
Beug ST, Tang VA, Lacasse EC, Cheung HH, Beauregard CE, Brun J et al. Smac mimetics and innate immune stimuli synergize to promote tumor death. Nat Biotechnol 2014; 32: 182-190.
-
(2014)
Nat Biotechnol
, vol.32
, pp. 182-190
-
-
Beug, S.T.1
Tang, V.A.2
Lacasse, E.C.3
Cheung, H.H.4
Beauregard, C.E.5
Brun, J.6
-
31
-
-
0026681218
-
An immortalized cell line expresses properties of activated microglial cells
-
Bocchini V, Mazzolla R, Barluzzi R, Blasi E, Sick P, Kettenmann H. An immortalized cell line expresses properties of activated microglial cells. J Neurosci Res 1992; 31: 616-621.
-
(1992)
J Neurosci Res
, vol.31
, pp. 616-621
-
-
Bocchini, V.1
Mazzolla, R.2
Barluzzi, R.3
Blasi, E.4
Sick, P.5
Kettenmann, H.6
-
32
-
-
0346103669
-
P57(Kip2) cooperates with Nurr1 in developing dopamine cells
-
Joseph B, Wallen-Mackenzie A, Benoit G, Murata T, Joodmardi E, Okret S et al. p57(Kip2) cooperates with Nurr1 in developing dopamine cells. Proc Natl Acad Sci USA 2003; 100: 15619-15624.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 15619-15624
-
-
Joseph, B.1
Wallen-Mackenzie, A.2
Benoit, G.3
Murata, T.4
Joodmardi, E.5
Okret, S.6
|