메뉴 건너뛰기




Volumn 3, Issue 12, 2012, Pages

UPAR and cathepsin B shRNA impedes TGF-b1-driven proliferation and invasion of meningioma cells in a XIAP-dependent pathway

Author keywords

meningioma; shRNA; TGF 1; uPAR and cathepsin B; XIAP

Indexed keywords

CATHEPSIN B; GELATINASE A; GELATINASE B; SHORT HAIRPIN RNA; SMAD2 PROTEIN; TRANSFORMING GROWTH FACTOR BETA1; UROKINASE; UROKINASE RECEPTOR; X LINKED INHIBITOR OF APOPTOSIS;

EID: 84871234236     PISSN: None     EISSN: 20414889     Source Type: Journal    
DOI: 10.1038/cddis.2012.170     Document Type: Article
Times cited : (35)

References (40)
  • 1
    • 0000500583 scopus 로고    scopus 로고
    • Meningiomas pathology and genetics of tumours of the nervous system
    • Kleihues P, Cavenee WK (eds). World Health Organization IARC Press: Lyon
    • Louis DN, Scheithauer BW, Budka H, von Deimling A, Kepes JJ. Meningiomas pathology and genetics of tumours of the nervous system. In: Kleihues P, Cavenee WK (eds). World Health Organization Classification of Tumours. IARC Press: Lyon, 2000. pp 176-184.
    • (2000) Classification of Tumours , pp. 176-184
    • Louis, D.N.1    Scheithauer, B.W.2    Budka, H.3    Von Deimling, A.4    Kepes, J.J.5
  • 2
    • 33846675282 scopus 로고    scopus 로고
    • Mechanisms underlying TGF-beta1-induced expression of VEGF and Flk-1 in mouse macrophages and their implications for angiogenesis
    • Jeon SH, Chae BC, Kim HA, Seo GY, Seo DW, Chun GT et al. Mechanisms underlying TGF-beta1-induced expression of VEGF and Flk-1 in mouse macrophages and their implications for angiogenesis. J Leukoc Biol 2007; 81: 557-566.
    • (2007) J Leukoc Biol , vol.81 , pp. 557-566
    • Jeon, S.H.1    Chae, B.C.2    Kim, H.A.3    Seo, G.Y.4    Seo, D.W.5    Chun, G.T.6
  • 3
    • 0036086409 scopus 로고    scopus 로고
    • Blockade of TGF-beta inhibits mammary tumor cell viability, migration, and metastases
    • Muraoka RS, Dumont N, Ritter CA, Dugger TC, Brantley DM, Chen J et al. Blockade of TGF-beta inhibits mammary tumor cell viability, migration, and metastases. J Clin Invest 2002; 109: 1551-1559.
    • (2002) J Clin Invest , vol.109 , pp. 1551-1559
    • Muraoka, R.S.1    Dumont, N.2    Ritter, C.A.3    Dugger, T.C.4    Brantley, D.M.5    Chen, J.6
  • 4
    • 0031106404 scopus 로고    scopus 로고
    • Transforming growth factor-beta: Vasculogenesis, angiogenesis, and vessel wall integrity
    • Pepper MS. Transforming growth factor-beta: vasculogenesis, angiogenesis, and vessel wall integrity. Cytokine Growth Factor Rev 1997; 8: 21-43.
    • (1997) Cytokine Growth Factor Rev , vol.8 , pp. 21-43
    • Pepper, M.S.1
  • 5
    • 33746701947 scopus 로고    scopus 로고
    • Elevated plasma TGF-beta1 levels correlate with decreased survival of metastatic breast cancer patients
    • Ivanovic V, Demajo M, Krtolica K, Krajnovic M, Konstantinovic M, Baltic V et al. Elevated plasma TGF-beta1 levels correlate with decreased survival of metastatic breast cancer patients. Clin Chim Acta 2006; 371: 191-193.
    • (2006) Clin Chim Acta , vol.371 , pp. 191-193
    • Ivanovic, V.1    Demajo, M.2    Krtolica, K.3    Krajnovic, M.4    Konstantinovic, M.5    Baltic, V.6
  • 7
    • 15744372725 scopus 로고    scopus 로고
    • Role of transforming growth factor beta in human cancer
    • Elliott RL, Blobe GC. Role of transforming growth factor beta in human cancer. J Clin Oncol 2005; 23: 2078-2093.
    • (2005) J Clin Oncol , vol.23 , pp. 2078-2093
    • Elliott, R.L.1    Blobe, G.C.2
  • 8
    • 0028921873 scopus 로고
    • Drug resistance and gene amplification potential regulated by transforming growth factor beta 1 gene expression
    • Huang A, Jin H, Wright JA. Drug resistance and gene amplification potential regulated by transforming growth factor beta 1 gene expression. Cancer Res 1995; 55: 1758-1762.
    • (1995) Cancer Res , vol.55 , pp. 1758-1762
    • Huang, A.1    Jin, H.2    Wright, J.A.3
  • 9
    • 33746145265 scopus 로고    scopus 로고
    • Inhibition of pulmonary and skeletal metastasis by a transforming growth factor-beta type i receptor kinase inhibitor
    • Bandyopadhyay A, Agyin JK, Wang L, Tang Y, Lei X, Story BM et al. Inhibition of pulmonary and skeletal metastasis by a transforming growth factor-beta type I receptor kinase inhibitor. Cancer Res 2006; 66: 6714-6721.
    • (2006) Cancer Res , vol.66 , pp. 6714-6721
    • Bandyopadhyay, A.1    Agyin, J.K.2    Wang, L.3    Tang, Y.4    Lei, X.5    Story, B.M.6
  • 10
    • 79951797048 scopus 로고    scopus 로고
    • The transforming growth factor-beta (TGF-beta) mediates acquisition of a mesenchymal stem cell-like phenotype in human liver cells
    • Caja L, Bertran E, Campbell J, Fausto N, Fabregat I. The transforming growth factor-beta (TGF-beta) mediates acquisition of a mesenchymal stem cell-like phenotype in human liver cells. J Cell Physiol 2011; 226: 1214-1223.
    • (2011) J Cell Physiol , vol.226 , pp. 1214-1223
    • Caja, L.1    Bertran, E.2    Campbell, J.3    Fausto, N.4    Fabregat, I.5
  • 11
    • 28544450380 scopus 로고    scopus 로고
    • Transforming growth factor-beta activation of phosphatidylinositol 3-kinase is independent of Smad2 and Smad3 and regulates fibroblast responses via p21-activated kinase-2
    • Wilkes MC, Mitchell H, Penheiter SG, Dore JJ, Suzuki K, Edens M et al. Transforming growth factor-beta activation of phosphatidylinositol 3-kinase is independent of Smad2 and Smad3 and regulates fibroblast responses via p21-activated kinase-2. Cancer Res 2005; 65: 10431-10440.
    • (2005) Cancer Res , vol.65 , pp. 10431-10440
    • Wilkes, M.C.1    Mitchell, H.2    Penheiter, S.G.3    Dore, J.J.4    Suzuki, K.5    Edens, M.6
  • 12
    • 0027535914 scopus 로고
    • Biology and biochemistry of proteinases in tumor invasion
    • Mignatti P, Rifkin DB. Biology and biochemistry of proteinases in tumor invasion. Physiol Rev 1993; 73: 161-195.
    • (1993) Physiol Rev , vol.73 , pp. 161-195
    • Mignatti, P.1    Rifkin, D.B.2
  • 13
    • 0034996039 scopus 로고    scopus 로고
    • The role of the plasminogen activation system in angiogenesis and metastasis
    • Rabbani SA, Mazar AP. The role of the plasminogen activation system in angiogenesis and metastasis. Surg Oncol Clin N Am 2001; 10: 393-415.
    • (2001) Surg Oncol Clin N Am , vol.10 , pp. 393-415
    • Rabbani, S.A.1    Mazar, A.P.2
  • 15
    • 0029088419 scopus 로고
    • Transcriptional and post-transcriptional regulation of the receptor for urokinase-type plasminogen activator by cytokines and tumour promoters in the human lung carcinoma cell line A549
    • Lund LR, Ellis V, Ronne E, Pyke C, Dano K. Transcriptional and post-transcriptional regulation of the receptor for urokinase-type plasminogen activator by cytokines and tumour promoters in the human lung carcinoma cell line A549. Biochem J 1995; 310: 345-352.
    • (1995) Biochem J , vol.310 , pp. 345-352
    • Lund, L.R.1    Ellis, V.2    Ronne, E.3    Pyke, C.4    Dano, K.5
  • 16
    • 77955540696 scopus 로고    scopus 로고
    • XIAP gene expression and function is regulated by autocrine and paracrine TGF-beta signaling
    • Van Themsche C, Chaudhry P, Leblanc V, Parent S, Asselin E. XIAP gene expression and function is regulated by autocrine and paracrine TGF-beta signaling. Mol Cancer 2010; 9: 216 216.
    • (2010) Mol Cancer , vol.9 , pp. 216
    • Van Themsche, C.1    Chaudhry, P.2    Leblanc, V.3    Parent, S.4    Asselin, E.5
  • 17
    • 77951231397 scopus 로고    scopus 로고
    • TGF-beta signaling, tumor microenvironment and tumor progression: The butterfly effect
    • Joshi A, Cao D. TGF-beta signaling, tumor microenvironment and tumor progression: the butterfly effect. Front Biosci 2010; 15: 180-194.
    • (2010) Front Biosci , vol.15 , pp. 180-194
    • Joshi, A.1    Cao, D.2
  • 18
    • 77649094900 scopus 로고    scopus 로고
    • Transforming growth factor-beta: A target for cancer therapy
    • Kelly RJ, Morris JC. Transforming growth factor-beta: a target for cancer therapy. J Immunotoxicol 2010; 7: 15-26.
    • (2010) J Immunotoxicol , vol.7 , pp. 15-26
    • Kelly, R.J.1    Morris, J.C.2
  • 19
    • 33745515023 scopus 로고    scopus 로고
    • Tumour microenvironment: TGFbeta: The molecular Jekyll and Hyde of cancer
    • Bierie B, Moses HL. Tumour microenvironment: TGFbeta: the molecular Jekyll and Hyde of cancer. Nat Rev Cancer 2006; 6: 506-520.
    • (2006) Nat Rev Cancer , vol.6 , pp. 506-520
    • Bierie, B.1    Moses, H.L.2
  • 20
    • 0242543345 scopus 로고    scopus 로고
    • Concentration-dependent bifunctional effect of TGF-beta 1 on immunoglobulin production: A role for Smad3 in IgA production in vitro
    • McKarns SC, Letterio JJ, Kaminski NE. Concentration-dependent bifunctional effect of TGF-beta 1 on immunoglobulin production: a role for Smad3 in IgA production in vitro. Int Immunopharmacol 2003; 3: 1761-1774.
    • (2003) Int Immunopharmacol , vol.3 , pp. 1761-1774
    • McKarns, S.C.1    Letterio, J.J.2    Kaminski, N.E.3
  • 21
    • 0034146494 scopus 로고    scopus 로고
    • TGF-beta1,-beta2, and-beta3 in vitro: Biphasic effects on Tenon's fibroblast contraction, proliferation, and migration
    • Cordeiro MF, Bhattacharya SS, Schultz GS, Khaw PT. TGF-beta1,-beta2, and-beta3 in vitro: biphasic effects on Tenon's fibroblast contraction, proliferation, and migration. Invest Ophthalmol Vis Sci 2000; 41: 756-763.
    • (2000) Invest Ophthalmol Vis Sci , vol.41 , pp. 756-763
    • Cordeiro, M.F.1    Bhattacharya, S.S.2    Schultz, G.S.3    Khaw, P.T.4
  • 22
    • 0041737535 scopus 로고    scopus 로고
    • Molecular mechanisms of glioma invasiveness: The role of proteases
    • Rao JS. Molecular mechanisms of glioma invasiveness: the role of proteases. Nat Rev Cancer 2003; 3: 489-501.
    • (2003) Nat Rev Cancer , vol.3 , pp. 489-501
    • Rao, J.S.1
  • 23
    • 0035879867 scopus 로고    scopus 로고
    • TGF-beta-induced invasiveness of pancreatic cancer cells is mediated by matrix metalloproteinase-2 and the urokinase plasminogen activator system
    • Ellenrieder V, Hendler SF, Ruhland C, Boeck W, Adler G, Gress TM. TGF-beta-induced invasiveness of pancreatic cancer cells is mediated by matrix metalloproteinase-2 and the urokinase plasminogen activator system. Int J Cancer 2001; 93: 204-211.
    • (2001) Int J Cancer , vol.93 , pp. 204-211
    • Ellenrieder, V.1    Hendler, S.F.2    Ruhland, C.3    Boeck, W.4    Adler, G.5    Gress, T.M.6
  • 24
    • 0038485575 scopus 로고    scopus 로고
    • TGF-beta1 suppresses apoptosis via differential regulation of MAP kinases and ceramide production
    • Chen HH, Zhao S, Song JG. TGF-beta1 suppresses apoptosis via differential regulation of MAP kinases and ceramide production. Cell Death Differ 2003; 10: 516-527.
    • (2003) Cell Death Differ , vol.10 , pp. 516-527
    • Chen, H.H.1    Zhao, S.2    Song, J.G.3
  • 25
    • 10344255835 scopus 로고    scopus 로고
    • TGF-beta-induced upregulation of MMP-2 and MMP-9 depends on p38 MAPK, but not ERK signaling in MCF10A human breast epithelial cells
    • Kim ES, Kim MS, Moon A. TGF-beta-induced upregulation of MMP-2 and MMP-9 depends on p38 MAPK, but not ERK signaling in MCF10A human breast epithelial cells. Int J Oncol 2004; 25: 1375-1382.
    • (2004) Int J Oncol , vol.25 , pp. 1375-1382
    • Kim, E.S.1    Kim, M.S.2    Moon, A.3
  • 26
    • 79952326174 scopus 로고    scopus 로고
    • Oncogenic role of p53 is suppressed by si-RNA bicistronic construct of uPA, uPAR and cathepsin-B in meningiomas both in vitro and in vivo
    • Gupta R, Rao GV, Nalla AK, Chetty C, Klopfenstein JD, Tsung AJ et al. Oncogenic role of p53 is suppressed by si-RNA bicistronic construct of uPA, uPAR and cathepsin-B in meningiomas both in vitro and in vivo. Int J Oncol 2011; 38: 973-983.
    • (2011) Int J Oncol , vol.38 , pp. 973-983
    • Gupta, R.1    Rao, G.V.2    Nalla, A.K.3    Chetty, C.4    Klopfenstein, J.D.5    Tsung, A.J.6
  • 28
    • 80054986175 scopus 로고    scopus 로고
    • Rezacova M. p21Cip1/Waf1 protein and its function based on a subcellular localization [corrected]
    • Cmielova J, Rezacova M. p21Cip1/Waf1 protein and its function based on a subcellular localization [corrected]. J Cell Biochem 2011; 112: 3502-3506.
    • (2011) J Cell Biochem , vol.112 , pp. 3502-3506
    • Cmielova, J.1
  • 29
    • 35348847256 scopus 로고    scopus 로고
    • Transforming growth factor-beta signaling in cancer invasion and metastasis
    • Leivonen SK, Kahari VM. Transforming growth factor-beta signaling in cancer invasion and metastasis. Int J Cancer 2007; 121: 2119-2124.
    • (2007) Int J Cancer , vol.121 , pp. 2119-2124
    • Leivonen, S.K.1    Kahari, V.M.2
  • 30
    • 0042704734 scopus 로고    scopus 로고
    • Cross-talk between ERK MAP kinase and Smad signaling pathways enhances TGF-beta-dependent responses in human mesangial cells
    • Hayashida T, Decaestecker M, Schnaper HW. Cross-talk between ERK MAP kinase and Smad signaling pathways enhances TGF-beta-dependent responses in human mesangial cells. FASEB J 2003; 17: 1576-1578.
    • (2003) FASEB J , vol.17 , pp. 1576-1578
    • Hayashida, T.1    Decaestecker, M.2    Schnaper, H.W.3
  • 31
    • 79953172581 scopus 로고    scopus 로고
    • TGF-beta1-induced PI3K/Akt/NF-kappaB/MMP9 signalling pathway is activated in Philadelphia chromosome-positive chronic myeloid leukaemia hemangioblasts
    • Zhu X, Wang L, Zhang B, Li J, Dou X, Zhao RC. TGF-beta1-induced PI3K/Akt/NF-kappaB/MMP9 signalling pathway is activated in Philadelphia chromosome-positive chronic myeloid leukaemia hemangioblasts. J Biochem 2011; 149: 405-414.
    • (2011) J Biochem , vol.149 , pp. 405-414
    • Zhu, X.1    Wang, L.2    Zhang, B.3    Li, J.4    Dou, X.5    Zhao, R.C.6
  • 32
    • 0142104985 scopus 로고    scopus 로고
    • Smad-dependent and Smad-independent pathways in TGF-beta family signalling
    • Derynck R, Zhang YE. Smad-dependent and Smad-independent pathways in TGF-beta family signalling. Nature 2003; 425: 577-584.
    • (2003) Nature , vol.425 , pp. 577-584
    • Derynck, R.1    Zhang, Y.E.2
  • 33
    • 1242317030 scopus 로고    scopus 로고
    • Akt phosphorylation and stabilization of X-linked inhibitor of apoptosis protein (XIAP
    • Dan HC, Sun M, Kaneko S, Feldman RI, Nicosia SV, Wang HG et al. Akt phosphorylation and stabilization of X-linked inhibitor of apoptosis protein (XIAP). J Biol Chem 2004; 279: 5405-5412.
    • (2004) J Biol Chem , vol.279 , pp. 5405-5412
    • Dan, H.C.1    Sun, M.2    Kaneko, S.3    Feldman, R.I.4    Nicosia, S.V.5    Wang, H.G.6
  • 34
    • 35448991324 scopus 로고    scopus 로고
    • Extracellular control of TGFbeta signalling in vascular development and disease
    • ten Dijke P, Arthur HM. Extracellular control of TGFbeta signalling in vascular development and disease. Nat Rev Mol Cell Biol 2007; 8: 857-869.
    • (2007) Nat Rev Mol Cell Biol , vol.8 , pp. 857-869
    • Ten Dijke, P.1    Arthur, H.M.2
  • 35
    • 0028984569 scopus 로고
    • Characterization of latent TGF-beta activation by murine peritoneal macrophages
    • Nunes I, Shapiro RL, Rifkin DB. Characterization of latent TGF-beta activation by murine peritoneal macrophages. J Immunol 1995; 155: 1450-1459.
    • (1995) J Immunol , vol.155 , pp. 1450-1459
    • Nunes, I.1    Shapiro, R.L.2    Rifkin, D.B.3
  • 36
    • 3042551389 scopus 로고    scopus 로고
    • Adenovirusmediated expression of antisense urokinase plasminogen activator receptor and antisense cathepsin B inhibits tumor growth, invasion, and angiogenesis in gliomas
    • Gondi CS, Lakka SS, Yanamandra N, Olivero WC, Dinh DH, Gujrati M et al. Adenovirusmediated expression of antisense urokinase plasminogen activator receptor and antisense cathepsin B inhibits tumor growth, invasion, and angiogenesis in gliomas. Cancer Res 2004; 64: 4069-4077.
    • (2004) Cancer Res , vol.64 , pp. 4069-4077
    • Gondi, C.S.1    Lakka, S.S.2    Yanamandra, N.3    Olivero, W.C.4    Dinh, D.H.5    Gujrati, M.6
  • 37
    • 79951819880 scopus 로고    scopus 로고
    • UPAR/cathepsin B overexpression reverse angiogenesis by rescuing FAK phosphorylation in uPAR/cathepsin B down regulated meningioma
    • Gupta R, Nalla AK, Gogineni VR, Chetty C, Bhoopathi P, Klopfenstein JD et al. uPAR/cathepsin B overexpression reverse angiogenesis by rescuing FAK phosphorylation in uPAR/cathepsin B down regulated meningioma. PLoS One 2011; 6: e17123.
    • (2011) PLoS One , vol.6
    • Gupta, R.1    Nalla, A.K.2    Gogineni, V.R.3    Chetty, C.4    Bhoopathi, P.5    Klopfenstein, J.D.6
  • 38
    • 2942718949 scopus 로고    scopus 로고
    • Inhibition of cathepsin B and MMP-9 gene expression in glioblastoma cell line via RNA interference reduces tumor cell invasion, tumor growth and angiogenesis
    • Lakka SS, Gondi CS, Yanamandra N, Olivero WC, Dinh DH, Gujrati M et al. Inhibition of cathepsin B and MMP-9 gene expression in glioblastoma cell line via RNA interference reduces tumor cell invasion, tumor growth and angiogenesis. Oncogene 2004; 23: 4681-4689.
    • (2004) Oncogene , vol.23 , pp. 4681-4689
    • Lakka, S.S.1    Gondi, C.S.2    Yanamandra, N.3    Olivero, W.C.4    Dinh, D.H.5    Gujrati, M.6
  • 39
    • 0141841681 scopus 로고    scopus 로고
    • Expression of antisense uPAR and antisense uPA from a bicistronic adenoviral construct inhibits glioma cell invasion, tumor growth, and angiogenesis
    • Gondi CS, Lakka SS, Yanamandra N, Siddique K, Dinh DH, Olivero WC et al. Expression of antisense uPAR and antisense uPA from a bicistronic adenoviral construct inhibits glioma cell invasion, tumor growth, and angiogenesis. Oncogene 2003; 22: 5967-5975.
    • (2003) Oncogene , vol.22 , pp. 5967-5975
    • Gondi, C.S.1    Lakka, S.S.2    Yanamandra, N.3    Siddique, K.4    Dinh, D.H.5    Olivero, W.C.6
  • 40
    • 0033974165 scopus 로고    scopus 로고
    • Intracranial injection of human meningioma cells in athymic mice: An orthotopic model for meningioma growth
    • McCutcheon IE, Friend KE, Gerdes TM, Zhang BM, Wildrick DM, Fuller GN. Intracranial injection of human meningioma cells in athymic mice: an orthotopic model for meningioma growth. J Neurosurg 2000; 92: 306-314.
    • (2000) J Neurosurg , vol.92 , pp. 306-314
    • McCutcheon, I.E.1    Friend, K.E.2    Gerdes, T.M.3    Zhang, B.M.4    Wildrick, D.M.5    Fuller, G.N.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.