-
1
-
-
46049095090
-
Heat-shock proteins
-
Appendix 1: Appendix 1T doi:10.1002/0471142735.ima01ts58
-
Li Z, Srivastava P. Heat-shock proteins. Curr Protoc Immunol 2004, Appendix 1: Appendix 1T; doi:10.1002/0471142735.ima01ts58.
-
(2004)
Curr Protoc Immunol
-
-
Li, Z.1
Srivastava, P.2
-
3
-
-
84865618692
-
Inhibition of HSP70: A challenging anti-cancer strategy
-
Goloudina AR, Demidov ON, Garrido C. Inhibition of HSP70: a challenging anti-cancer strategy. Cancer Lett 2012; 325: 117-124.
-
(2012)
Cancer Lett
, vol.325
, pp. 117-124
-
-
Goloudina, A.R.1
Demidov, O.N.2
Garrido, C.3
-
4
-
-
84879589788
-
The PI3K/Akt signalling pathway regulates the expression of Hsp70, which critically contributes to Hsp90-chaperone function and tumor cell survival inmultiple myeloma
-
Chatterjee M, Andrulis M, Stuhmer T, Muller E, Hofmann C, Steinbrunn T et al. The PI3K/Akt signalling pathway regulates the expression of Hsp70, which critically contributes to Hsp90-chaperone function and tumor cell survival inmultiple myeloma. Haematologica 2012; 98: 1132-1141.
-
(2012)
Haematologica
, vol.98
, pp. 1132-1141
-
-
Chatterjee, M.1
Andrulis, M.2
Stuhmer, T.3
Muller, E.4
Hofmann, C.5
Steinbrunn, T.6
-
5
-
-
80054753125
-
Hsp70: Anti-apoptotic and tumorigenic protein
-
Rerole AL, Jego G, Garrido C. Hsp70: anti-apoptotic and tumorigenic protein. Methods Mol Biol 2011; 787: 205-230.
-
(2011)
Methods Mol Biol
, vol.787
, pp. 205-230
-
-
Rerole, A.L.1
Jego, G.2
Garrido, C.3
-
6
-
-
84873971170
-
Suppression of HSP70 expression sensitizes NSCLC cell lines to TRAIL-induced apoptosis by upregulating DR4 and DR5 and downregulating c-FLIP-L expressions
-
Zhuang H, Jiang W, Zhang X, Qiu F, Gan Z, Cheng W et al. Suppression of HSP70 expression sensitizes NSCLC cell lines to TRAIL-induced apoptosis by upregulating DR4 and DR5 and downregulating c-FLIP-L expressions. J Mol Med (Berl) 2013; 91: 219-235.
-
(2013)
J Mol Med (Berl)
, vol.91
, pp. 219-235
-
-
Zhuang, H.1
Jiang, W.2
Zhang, X.3
Qiu, F.4
Gan, Z.5
Cheng, W.6
-
7
-
-
33845913216
-
Intracellular and extracellular functions of heat shock proteins: Repercussions in cancer therapy
-
Schmitt E, Gehrmann M, Brunet M, Multhoff G, Garrido C. Intracellular and extracellular functions of heat shock proteins: repercussions in cancer therapy. J Leukocyte Biol 2007; 81: 15-27.
-
(2007)
J Leukocyte Biol
, vol.81
, pp. 15-27
-
-
Schmitt, E.1
Gehrmann, M.2
Brunet, M.3
Multhoff, G.4
Garrido, C.5
-
8
-
-
0037115547
-
Eradication of glioblastoma, and breast and colon carcinoma xenografts by Hsp70 depletion
-
Nylandsted J, Wick W, Hirt UA, Brand K, Rohde M, Leist M et al. Eradication of glioblastoma, and breast and colon carcinoma xenografts by Hsp70 depletion. Cancer Res 2002; 62: 7139-7142.
-
(2002)
Cancer Res
, vol.62
, pp. 7139-7142
-
-
Nylandsted, J.1
Wick, W.2
Hirt, U.A.3
Brand, K.4
Rohde, M.5
Leist, M.6
-
9
-
-
0035829740
-
Selective depletion of inducible HSP70 enhances immunogenicity of rat colon cancer cells
-
Gurbuxani S, Bruey JM, Fromentin A, Larmonier N, Parcellier A, Jaattela M et al. Selective depletion of inducible HSP70 enhances immunogenicity of rat colon cancer cells. Oncogene 2001; 20: 7478-7485.
-
(2001)
Oncogene
, vol.20
, pp. 7478-7485
-
-
Gurbuxani, S.1
Bruey, J.M.2
Fromentin, A.3
Larmonier, N.4
Parcellier, A.5
Jaattela, M.6
-
10
-
-
70349768075
-
A small molecule inhibitor of inducible heat shock protein 70
-
Leu JI, Pimkina J, Frank A, Murphy ME, George DL. A small molecule inhibitor of inducible heat shock protein 70. Mol Cell 2009; 36: 15-27.
-
(2009)
Mol Cell
, vol.36
, pp. 15-27
-
-
Leu, J.I.1
Pimkina, J.2
Frank, A.3
Murphy, M.E.4
George, D.L.5
-
11
-
-
79960694363
-
HSP70 inhibition by the small-molecule 2-phenylethynesulfonamide impairs protein clearance pathways in tumor cells
-
Leu JI, Pimkina J, Pandey P, Murphy ME, George DL. HSP70 inhibition by the small-molecule 2-phenylethynesulfonamide impairs protein clearance pathways in tumor cells. Mol Cancer Res 2011; 9: 936-947.
-
(2011)
Mol Cancer Res
, vol.9
, pp. 936-947
-
-
Leu, J.I.1
Pimkina, J.2
Pandey, P.3
Murphy, M.E.4
George, D.L.5
-
12
-
-
84864029423
-
Antileukemic activity of the HSP70 inhibitor pifithrin-mu in acute leukemia
-
Kaiser M, Kuhnl A, Reins J, Fischer S, Ortiz-Tanchez J, Schlee C et al. Antileukemic activity of the HSP70 inhibitor pifithrin-mu in acute leukemia. Blood Cancer J 2011; 1: e28.
-
(2011)
Blood Cancer J
, vol.1
-
-
Kaiser, M.1
Kuhnl, A.2
Reins, J.3
Fischer, S.4
Ortiz-Tanchez, J.5
Schlee, C.6
-
13
-
-
4344651318
-
Heat shock protein 70 promotes cell survival by inhibiting lysosomal membrane permeabilization
-
Nylandsted J, Gyrd-Hansen M, Danielewicz A, Fehrenbacher N, Lademann U, Hoyer-Hansen M et al. Heat shock protein 70 promotes cell survival by inhibiting lysosomal membrane permeabilization. J Exp Med 2004; 200: 425-435.
-
(2004)
J Exp Med
, vol.200
, pp. 425-435
-
-
Nylandsted, J.1
Gyrd-Hansen, M.2
Danielewicz, A.3
Fehrenbacher, N.4
Lademann, U.5
Hoyer-Hansen, M.6
-
14
-
-
77954164469
-
Connecting Hsp70, sphingolipid metabolism and lysosomal stability
-
Petersen NH, Kirkegaard T, Olsen OD, Jaattela M. Connecting Hsp70, sphingolipid metabolism and lysosomal stability. Cell Cycle 2010; 9: 2305-2309.
-
(2010)
Cell Cycle
, vol.9
, pp. 2305-2309
-
-
Petersen, N.H.1
Kirkegaard, T.2
Olsen, O.D.3
Jaattela, M.4
-
15
-
-
53049094306
-
Sensitization to the lysosomal cell death pathway by oncogene-induced down-regulation of lysosome-associated membrane proteins 1 and 2
-
Fehrenbacher N, Bastholm L, Kirkegaard-Sorensen T, Rafn B, Bottzauw T, Nielsen C et al. Sensitization to the lysosomal cell death pathway by oncogene-induced down-regulation of lysosome-associated membrane proteins 1 and 2. Cancer Res 2008; 68: 6623-6633.
-
(2008)
Cancer Res
, vol.68
, pp. 6623-6633
-
-
Fehrenbacher, N.1
Bastholm, L.2
Kirkegaard-Sorensen, T.3
Rafn, B.4
Bottzauw, T.5
Nielsen, C.6
-
16
-
-
75749102680
-
Hsp70 stabilizes lysosomes and reverts Niemann-Pick disease-associated lysosomal pathology
-
Kirkegaard T, Roth AG, Petersen NH, Mahalka AK, Olsen OD, Moilanen I et al. Hsp70 stabilizes lysosomes and reverts Niemann-Pick disease-associated lysosomal pathology. Nature 2010; 463:: 549-553.
-
(2010)
Nature
, vol.463
, pp. 549-553
-
-
Kirkegaard, T.1
Roth, A.G.2
Petersen, N.H.3
Mahalka, A.K.4
Olsen, O.D.5
Moilanen, I.6
-
17
-
-
54949137644
-
Lysosomal membrane permeabilization in cell death
-
Boya P, Kroemer G. Lysosomal membrane permeabilization in cell death. Oncogene 2008; 27: 6434-6451.
-
(2008)
Oncogene
, vol.27
, pp. 6434-6451
-
-
Boya, P.1
Kroemer, G.2
-
18
-
-
84872444027
-
Clearing the final hurdles to mitochondrial apoptosis: Regulation post cytochrome C release
-
Monian P, Jiang X. Clearing the final hurdles to mitochondrial apoptosis: regulation post cytochrome C release. Exp Oncol 2012; 34: 185-191.
-
(2012)
Exp Oncol
, vol.34
, pp. 185-191
-
-
Monian, P.1
Jiang, X.2
-
19
-
-
67449155856
-
Granulysin induces cathepsin B release from lysosomes of target tumor cells to attack mitochondria through processing of bid leading to Necroptosis
-
Zhang H, Zhong C, Shi L, Guo Y, Fan Z. Granulysin induces cathepsin B release from lysosomes of target tumor cells to attack mitochondria through processing of bid leading to Necroptosis. J Immunol 2009; 182: 6993-7000.
-
(2009)
J Immunol
, vol.182
, pp. 6993-7000
-
-
Zhang, H.1
Zhong, C.2
Shi, L.3
Guo, Y.4
Fan, Z.5
-
20
-
-
0029974841
-
Primary effusion lymphoma: A distinct clinicopathologic entity associated with the Kaposi's sarcoma-associated herpes virus
-
Nador RG, Cesarman E, Chadburn A, Dawson DB, Ansari MQ, Sald J et al. Primary effusion lymphoma: a distinct clinicopathologic entity associated with the Kaposi's sarcoma-associated herpes virus. Blood 1996; 88: 645-656.
-
(1996)
Blood
, vol.88
, pp. 645-656
-
-
Nador, R.G.1
Cesarman, E.2
Chadburn, A.3
Dawson, D.B.4
Ansari, M.Q.5
Sald, J.6
-
21
-
-
0036310279
-
Microinjection of cathepsin d induces caspase-dependent apoptosis in fibroblasts
-
Roberg K, Kagedal K, Ollinger K. Microinjection of cathepsin d induces caspase-dependent apoptosis in fibroblasts. Am J Pathol 2002; 161: 89-96.
-
(2002)
Am J Pathol
, vol.161
, pp. 89-96
-
-
Roberg, K.1
Kagedal, K.2
Ollinger, K.3
-
22
-
-
28544435485
-
Lysosomes and autophagy in cell death control
-
Kroemer G, Jaattela M. Lysosomes and autophagy in cell death control. Nat Rev Cancer 2005; 5: 886-897.
-
(2005)
Nat Rev Cancer
, vol.5
, pp. 886-897
-
-
Kroemer, G.1
Jaattela, M.2
-
23
-
-
84857873299
-
Autophagy and cancer
-
Choi KS. Autophagy and cancer. Exp Mol Med 2012; 44: 109-120.
-
(2012)
Exp Mol Med
, vol.44
, pp. 109-120
-
-
Choi, K.S.1
-
24
-
-
0035433420
-
Four deaths and a funeral: From caspases to alternative mechanisms
-
Leist M, Jaattela M. Four deaths and a funeral: from caspases to alternative mechanisms. Nat Rev Mol Cell Biol 2001; 2: 589-598.
-
(2001)
Nat Rev Mol Cell Biol
, vol.2
, pp. 589-598
-
-
Leist, M.1
Jaattela, M.2
-
26
-
-
34547100575
-
Caspase-8-mediated apoptosis induced by oxidative stress is independent of the intrinsic pathway and dependent on cathepsins
-
Baumgartner HK, Gerasimenko JV, Thorne C, Ashurst LH, Barrow SL, Chvanov MA et al. Caspase-8-mediated apoptosis induced by oxidative stress is independent of the intrinsic pathway and dependent on cathepsins. Am J Physiol Gastrointest Liver Physiol 2007; 293: G296-G307.
-
(2007)
Am J Physiol Gastrointest Liver Physiol
, vol.293
-
-
Baumgartner, H.K.1
Gerasimenko, J.V.2
Thorne, C.3
Ashurst, L.H.4
Barrow, S.L.5
Chvanov, M.A.6
-
27
-
-
84868657087
-
Lysosome-mediated apoptosis is associated with cathepsin D-specific processing of bid at Phe24, Trp48, and Phe183
-
Appelqvist H, Johansson AC, Linderoth E, Johansson U, Antonsson B, Steinfeld R et al. Lysosome-mediated apoptosis is associated with cathepsin D-specific processing of bid at Phe24, Trp48, and Phe183. Ann Clin Lab Sci 2012; 42: 231-242.
-
(2012)
Ann Clin Lab Sci
, vol.42
, pp. 231-242
-
-
Appelqvist, H.1
Johansson, A.C.2
Linderoth, E.3
Johansson, U.4
Antonsson, B.5
Steinfeld, R.6
-
28
-
-
84866163429
-
Phosphatidic acid mediates the targeting of tBid to induce lysosomal membrane permeabilization and apoptosis
-
Zhao K, Zhou H, Zhao X, Wolff DW, Tu Y, Liu H et al. Phosphatidic acid mediates the targeting of tBid to induce lysosomal membrane permeabilization and apoptosis. J Lipid Res 2012; 53: 2102-2114.
-
(2012)
J Lipid Res
, vol.53
, pp. 2102-2114
-
-
Zhao, K.1
Zhou, H.2
Zhao, X.3
Wolff, D.W.4
Tu, Y.5
Liu, H.6
-
29
-
-
17944366977
-
Heat-shock protein 70 antagonizes apoptosis-inducing factor
-
Ravagnan L, Gurbuxani S, Susin SA, Maisse C, Daugas E, Zamzami N et al. Heat-shock protein 70 antagonizes apoptosis-inducing factor. Nat Cell Biol 2001; 3: 839-843.
-
(2001)
Nat Cell Biol
, vol.3
, pp. 839-843
-
-
Ravagnan, L.1
Gurbuxani, S.2
Susin, S.A.3
Maisse, C.4
Daugas, E.5
Zamzami, N.6
-
30
-
-
84857879286
-
Primary effusion lymphoma cell death induced by bortezomib and AG 490 activates dendritic cells through CD91
-
Cirone M, Di Renzo L, Lotti LV, Conte V, Trivedi P, Santarelli R et al. Primary effusion lymphoma cell death induced by bortezomib and AG 490 activates dendritic cells through CD91. PloS One 2012; 7: e31732.
-
(2012)
PloS One
, vol.7
-
-
Cirone, M.1
Di Renzo, L.2
Lotti, L.V.3
Conte, V.4
Trivedi, P.5
Santarelli, R.6
-
31
-
-
79953171152
-
Lucanthone is a novel inhibitor of autophagy that induces cathepsin D-mediated apoptosis
-
Carew JS, Espitia CM, Esquivel JA 2nd, Mahalingam D, Kelly KR, Reddy G et al. Lucanthone is a novel inhibitor of autophagy that induces cathepsin D-mediated apoptosis. J Biol Chem 2011; 286: 6602-6613.
-
(2011)
J Biol Chem
, vol.286
, pp. 6602-6613
-
-
Carew, J.S.1
Espitia, C.M.2
Esquivel, I.I.J.A.3
Mahalingam, D.4
Kelly, K.R.5
Reddy, G.6
-
33
-
-
84870792928
-
Hsp90 inhibitors are efficacious against Kaposi Sarcoma by enhancing the degradation of the essential viral gene LANA, of the viral co-receptor EphA2 as well as other client proteins
-
Chen W, Sin SH, Wen KW, Damania B, Dittmer DP. Hsp90 inhibitors are efficacious against Kaposi Sarcoma by enhancing the degradation of the essential viral gene LANA, of the viral co-receptor EphA2 as well as other client proteins. PLoS Pathog 2012; 8: e1003048.
-
(2012)
PLoS Pathog
, vol.8
-
-
Chen, W.1
Sin, S.H.2
Wen, K.W.3
Damania, B.4
Dittmer, D.P.5
-
34
-
-
84875414858
-
A modified HSP70 inhibitor shows broad activity as an anticancer agent
-
Balaburski GM, Leu JI, Beeharry N, Hayik S, Andrake MD, Zhang G et al. A modified HSP70 inhibitor shows broad activity as an anticancer agent. Mol Cancer Res 2013; 11: 219-229.
-
(2013)
Mol Cancer Res
, vol.11
, pp. 219-229
-
-
Balaburski, G.M.1
Leu, J.I.2
Beeharry, N.3
Hayik, S.4
Andrake, M.D.5
Zhang, G.6
-
35
-
-
38549119467
-
Chaperones in control of protein disaggregation
-
Liberek K, Lewandowska A, Zietkiewicz S. Chaperones in control of protein disaggregation. EMBO J 2008; 27: 328-335.
-
(2008)
EMBO J
, vol.27
, pp. 328-335
-
-
Liberek, K.1
Lewandowska, A.2
Zietkiewicz, S.3
-
36
-
-
68049126282
-
Mutational analysis of TP53, PTEN, PIK3CA and CTNNB1/beta-catenin genes in human herpesvirus 8-associated primary effusion lymphoma
-
Boulanger E, Marchio A, Hong SS, Pineau P. Mutational analysis of TP53, PTEN, PIK3CA and CTNNB1/beta-catenin genes in human herpesvirus 8-associated primary effusion lymphoma. Haematologica 2009; 94: 1170-1174.
-
(2009)
Haematologica
, vol.94
, pp. 1170-1174
-
-
Boulanger, E.1
Marchio, A.2
Hong, S.S.3
Pineau, P.4
-
37
-
-
77950994646
-
Autophagy: Cellular and molecular mechanisms
-
Glick D, Barth S, Macleod KF. Autophagy: cellular and molecular mechanisms. J Pathol 2010; 221: 3-12.
-
(2010)
J Pathol
, vol.221
, pp. 3-12
-
-
Glick, D.1
Barth, S.2
MacLeod, K.F.3
-
40
-
-
10244279184
-
Mechanisms and functional significance of tumour-induced dendritic-cell defects
-
Gabrilovich D. Mechanisms and functional significance of tumour-induced dendritic-cell defects. Nat Rev Immunol 2004; 4: 941-952.
-
(2004)
Nat Rev Immunol
, vol.4
, pp. 941-952
-
-
Gabrilovich, D.1
-
41
-
-
50849145149
-
Suppression of dendritic cell differentiation through cytokines released by Primary Effusion Lymphoma cells
-
Cirone M, Lucania G, Aleandri S, Borgia G, Trivedi P, Cuomo L et al. Suppression of dendritic cell differentiation through cytokines released by Primary Effusion Lymphoma cells. Immunol Lett 2008; 120: 37-41.
-
(2008)
Immunol Lett
, vol.120
, pp. 37-41
-
-
Cirone, M.1
Lucania, G.2
Aleandri, S.3
Borgia, G.4
Trivedi, P.5
Cuomo, L.6
-
42
-
-
79953011498
-
Dendritic cell differentiation blocked by primary effusion lymphoma-released factors is partially restored by inhibition of P38 MAPK
-
Cirone M, Di Renzo L, Trivedi P, Lucania G, Borgia G, Frati L et al. Dendritic cell differentiation blocked by primary effusion lymphoma-released factors is partially restored by inhibition of P38 MAPK. Int J Immunopathol Pharmacol 2010; 23: 1079-1086.
-
(2010)
Int J Immunopathol Pharmacol
, vol.23
, pp. 1079-1086
-
-
Cirone, M.1
Di Renzo, L.2
Trivedi, P.3
Lucania, G.4
Borgia, G.5
Frati, L.6
-
43
-
-
84868676333
-
Targeting COX-2/PGE(2) pathway in HIPK2 knockdown cancer cells: Impact on dendritic cell maturation
-
Garufi A, Pistritto G, Ceci C, Di Renzo L, Santarelli R, Faggioni A et al. Targeting COX-2/PGE(2) pathway in HIPK2 knockdown cancer cells: impact on dendritic cell maturation. PloS One 2012; 7: e48342.
-
(2012)
PloS One
, vol.7
-
-
Garufi, A.1
Pistritto, G.2
Ceci, C.3
Di Renzo, L.4
Santarelli, R.5
Faggioni, A.6
-
44
-
-
84055183917
-
Inflammatory mediators hold the key to dendritic cell suppression and tumor progression
-
Sheng KC, Wright MD, Apostolopoulos V. Inflammatory mediators hold the key to dendritic cell suppression and tumor progression. Curr Med Chem 2011; 18: 5507-5518.
-
(2011)
Curr Med Chem
, vol.18
, pp. 5507-5518
-
-
Sheng, K.C.1
Wright, M.D.2
Apostolopoulos, V.3
-
45
-
-
84881036485
-
Activation of dendritic cells by tumor cell death
-
Cirone M, Di Renzo L, Lotti LV, Conte V, Trivedi P, Santarelli R et al. Activation of dendritic cells by tumor cell death. Oncoimmunology 2012; 1: 1218-1219.
-
(2012)
Oncoimmunology
, vol.1
, pp. 1218-1219
-
-
Cirone, M.1
Di Renzo, L.2
Lotti, L.V.3
Conte, V.4
Trivedi, P.5
Santarelli, R.6
-
46
-
-
84870572036
-
JNK2 is activated during ER stress and promotes cell survival
-
Raciti M, Lotti LV, Valia S, Pulcinelli FM, Di Renzo L. JNK2 is activated during ER stress and promotes cell survival. Cell Death Dis 2012; 3: e429.
-
(2012)
Cell Death Dis
, vol.3
-
-
Raciti, M.1
Lotti, L.V.2
Valia, S.3
Pulcinelli, F.M.4
Di Renzo, L.5
-
47
-
-
34648837341
-
Human herpesvirus 8 (HHV-8) inhibits monocyte differentiation into dendritic cells and impairs their immunostimulatory activity
-
Cirone M, Lucania G, Bergamo P, Trivedi P, Frati L, Faggioni A. Human herpesvirus 8 (HHV-8) inhibits monocyte differentiation into dendritic cells and impairs their immunostimulatory activity. Immunol Lett 2007; 113: 40-46.
-
(2007)
Immunol Lett
, vol.113
, pp. 40-46
-
-
Cirone, M.1
Lucania, G.2
Bergamo, P.3
Trivedi, P.4
Frati, L.5
Faggioni, A.6
|