-
1
-
-
17944378526
-
Activation by IKKalpha of a second, evolutionary conserved, NF-kappa B signaling pathway
-
doi: 10.1126/science.1062677
-
Senftleben U, Cao Y, Xiao G, Greten FR, Krahn G, Bonizzi G, et al. Activation by IKKalpha of a second, evolutionary conserved, NF-kappa B signaling pathway. Science (2001) 293:1495-9. doi: 10.1126/science.1062677.
-
(2001)
Science
, vol.293
, pp. 1495-1499
-
-
Senftleben, U.1
Cao, Y.2
Xiao, G.3
Greten, F.R.4
Krahn, G.5
Bonizzi, G.6
-
2
-
-
38849199203
-
Shared principles in NF-kappaB signaling
-
doi:10.1016/j.cell.2008.01.020
-
Hayden MS, Ghosh S. Shared principles in NF-kappaB signaling. Cell (2008) 132:344-62. doi:10.1016/j.cell.2008.01.020.
-
(2008)
Cell
, vol.132
, pp. 344-362
-
-
Hayden, M.S.1
Ghosh, S.2
-
3
-
-
0034745420
-
NF-kappaB-inducing kinase regulates the processing of NF-kappaB2 p100
-
doi:10.1016/S1097-2765(01)00187-3
-
Xiao G, Harhaj EW, Sun SC. NF-kappaB-inducing kinase regulates the processing of NF-kappaB2 p100. Mol Cell (2001) 7:401-9. doi:10.1016/S1097-2765(01)00187-3.
-
(2001)
Mol Cell
, vol.7
, pp. 401-409
-
-
Xiao, G.1
Harhaj, E.W.2
Sun, S.C.3
-
4
-
-
80054854922
-
Non-canonical NF-kappaB signaling activation and regulation: principles and perspectives
-
doi:10.1111/j.1600-065X.2011.01059.x
-
Razani B, Reichardt AD, Cheng G. Non-canonical NF-kappaB signaling activation and regulation: principles and perspectives. Immunol Rev (2011) 244:44-54. doi:10.1111/j.1600-065X.2011.01059.x.
-
(2011)
Immunol Rev
, vol.244
, pp. 44-54
-
-
Razani, B.1
Reichardt, A.D.2
Cheng, G.3
-
5
-
-
14544286868
-
TNF receptor (TNFR)-associated factor (TRAF) 3 serves as an inhibitor of TRAF2/5-mediated activation of the noncanonical NF-kappaB pathway by TRAF-binding TNFRs
-
doi:10.1073/pnas.0500187102
-
Hauer J, Puschner S, Ramakrishnan P, Simon U, Bongers M, Federle C, et al. TNF receptor (TNFR)-associated factor (TRAF) 3 serves as an inhibitor of TRAF2/5-mediated activation of the noncanonical NF-kappaB pathway by TRAF-binding TNFRs. Proc Natl Acad Sci U S A (2005) 102:2874-9. doi:10.1073/pnas.0500187102.
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 2874-2879
-
-
Hauer, J.1
Puschner, S.2
Ramakrishnan, P.3
Simon, U.4
Bongers, M.5
Federle, C.6
-
6
-
-
17344380531
-
TACI and BCMA are receptors for a TNF homologue implicated in B-cell autoimmune disease
-
doi:10.1038/35010115
-
Gross JA, Johnston J, Mudri S, Enselman R, Dillon SR, Madden K, et al. TACI and BCMA are receptors for a TNF homologue implicated in B-cell autoimmune disease. Nature (2000) 404:995-9. doi:10.1038/35010115.
-
(2000)
Nature
, vol.404
, pp. 995-999
-
-
Gross, J.A.1
Johnston, J.2
Mudri, S.3
Enselman, R.4
Dillon, S.R.5
Madden, K.6
-
7
-
-
0033522907
-
Identification and characterization of a novel cytokine, THANK, a TNF homologue that activates apoptosis, nuclear factor-kappaB, and c-Jun NH2-terminal kinase
-
doi:10.1074/jbc.274.23.15978
-
Mukhopadhyay A, Ni J, Zhai Y, Yu GL, Aggarwal BB. Identification and characterization of a novel cytokine, THANK, a TNF homologue that activates apoptosis, nuclear factor-kappaB, and c-Jun NH2-terminal kinase. J Biol Chem (1999) 274:15978-81. doi:10.1074/jbc.274.23.15978.
-
(1999)
J Biol Chem
, vol.274
, pp. 15978-15981
-
-
Mukhopadhyay, A.1
Ni, J.2
Zhai, Y.3
Yu, G.L.4
Aggarwal, B.B.5
-
8
-
-
0033532634
-
BAFF, a novel ligand of the tumor necrosis factor family, stimulates B cell growth
-
doi:10.1084/jem.189.11.1747
-
Schneider P, MacKay F, Steiner V, Hofmann K, Bodmer JL, Holler N, et al. BAFF, a novel ligand of the tumor necrosis factor family, stimulates B cell growth. J Exp Med (1999) 189:1747-56. doi:10.1084/jem.189.11.1747.
-
(1999)
J Exp Med
, vol.189
, pp. 1747-1756
-
-
Schneider, P.1
MacKay, F.2
Steiner, V.3
Hofmann, K.4
Bodmer, J.L.5
Holler, N.6
-
9
-
-
0032915632
-
TALL-1 is a novel member of the TNF family that is down-regulated by mitogens
-
Shu HB, Hu WH, Johnson H. TALL-1 is a novel member of the TNF family that is down-regulated by mitogens. J Leukoc Biol (1999) 65:680-3.
-
(1999)
J Leukoc Biol
, vol.65
, pp. 680-683
-
-
Shu, H.B.1
Hu, W.H.2
Johnson, H.3
-
10
-
-
0033538468
-
BLyS: member of the tumor necrosis factor family and B lymphocyte stimulator
-
doi:10.1126/science.285.5425.260
-
Moore PA, Belvedere O, Orr A, Pieri K, LaFleur DW, Feng P, et al. BLyS: member of the tumor necrosis factor family and B lymphocyte stimulator. Science (1999) 285:260-3. doi:10.1126/science.285.5425.260.
-
(1999)
Science
, vol.285
, pp. 260-263
-
-
Moore, P.A.1
Belvedere, O.2
Orr, A.3
Pieri, K.4
LaFleur, D.W.5
Feng, P.6
-
11
-
-
0038076049
-
Ligand-receptor binding revealed by the TNF family member TALL-1
-
doi:10.1038/nature01543
-
Liu Y, Hong X, Kappler J, Jiang L, Zhang R, Xu L, et al. Ligand-receptor binding revealed by the TNF family member TALL-1. Nature (2003) 423:49-56. doi:10.1038/nature01543.
-
(2003)
Nature
, vol.423
, pp. 49-56
-
-
Liu, Y.1
Hong, X.2
Kappler, J.3
Jiang, L.4
Zhang, R.5
Xu, L.6
-
12
-
-
0036183318
-
Crystal structure of sTALL-1 reveals a virus-like assembly of TNF family ligands
-
doi:10.1016/S0092-8674(02)00631-1
-
Liu Y, Xu L, Opalka N, Kappler J, Shu HB, Zhang G. Crystal structure of sTALL-1 reveals a virus-like assembly of TNF family ligands. Cell (2002) 108:383-94. doi:10.1016/S0092-8674(02)00631-1.
-
(2002)
Cell
, vol.108
, pp. 383-394
-
-
Liu, Y.1
Xu, L.2
Opalka, N.3
Kappler, J.4
Shu, H.B.5
Zhang, G.6
-
13
-
-
0141643347
-
DeltaBAFF, an alternate splice isoform that regulates receptor binding and biopresentation of the B cell survival cytokine, BAFF
-
doi:10.1074/jbc.M306852200
-
Gavin AL, Ait-Azzouzene D, Ware CF, Nemazee D. DeltaBAFF, an alternate splice isoform that regulates receptor binding and biopresentation of the B cell survival cytokine, BAFF. J Biol Chem (2003) 278:38220-8. doi:10.1074/jbc.M306852200.
-
(2003)
J Biol Chem
, vol.278
, pp. 38220-38228
-
-
Gavin, A.L.1
Ait-Azzouzene, D.2
Ware, C.F.3
Nemazee, D.4
-
14
-
-
21244506678
-
deltaBAFF, a splice isoform of BAFF, opposes full-length BAFF activity in vivo in transgenic mouse models
-
Gavin AL, Duong B, Skog P, Ait-Azzouzene D, Greaves DR, Scott ML, et al. deltaBAFF, a splice isoform of BAFF, opposes full-length BAFF activity in vivo in transgenic mouse models. J Immunol (2005) 175:319-28.
-
(2005)
J Immunol
, vol.175
, pp. 319-328
-
-
Gavin, A.L.1
Duong, B.2
Skog, P.3
Ait-Azzouzene, D.4
Greaves, D.R.5
Scott, M.L.6
-
15
-
-
0034764499
-
Biologically active APRIL is secreted following intracellular processing in the Golgi apparatus by furin convertase
-
doi:10.1093/embo-reports/kve198
-
Lopez-Fraga M, Fernandez R, Albar JP, Hahne M. Biologically active APRIL is secreted following intracellular processing in the Golgi apparatus by furin convertase. EMBO Rep (2001) 2:945-51. doi:10.1093/embo-reports/kve198.
-
(2001)
EMBO Rep
, vol.2
, pp. 945-951
-
-
Lopez-Fraga, M.1
Fernandez, R.2
Albar, J.P.3
Hahne, M.4
-
16
-
-
0036847318
-
An endogenous hybrid mRNA encodes TWE-PRIL, a functional cell surface TWEAK-APRIL fusion protein
-
doi:10.1093/emboj/cdf565
-
Pradet-Balade B, Medema JP, Lopez-Fraga M, Lozano JC, Kolfschoten GM, Picard A, et al. An endogenous hybrid mRNA encodes TWE-PRIL, a functional cell surface TWEAK-APRIL fusion protein. EMBO J (2002) 21:5711-20. doi:10.1093/emboj/cdf565.
-
(2002)
EMBO J
, vol.21
, pp. 5711-5720
-
-
Pradet-Balade, B.1
Medema, J.P.2
Lopez-Fraga, M.3
Lozano, J.C.4
Kolfschoten, G.M.5
Picard, A.6
-
17
-
-
48749100460
-
APRIL secreted by neutrophils binds to heparan sulfate proteoglycans to create plasma cell niches in human mucosa
-
doi:10.1172/JCI33760
-
Huard B, McKee T, Bosshard C, Durual S, Matthes T, Myit S, et al. APRIL secreted by neutrophils binds to heparan sulfate proteoglycans to create plasma cell niches in human mucosa. J Clin Invest (2008) 118:2887-95. doi:10.1172/JCI33760.
-
(2008)
J Clin Invest
, vol.118
, pp. 2887-2895
-
-
Huard, B.1
McKee, T.2
Bosshard, C.3
Durual, S.4
Matthes, T.5
Myit, S.6
-
18
-
-
70349314412
-
The proteoglycan (heparan sulfate proteoglycan) binding domain of APRIL serves as a platform for ligand multimerization and cross-linking
-
doi:10.1096/fj.08-124669
-
Kimberley FC, van Bostelen L, Cameron K, Hardenberg G, Marquart JA, Hahne M, et al. The proteoglycan (heparan sulfate proteoglycan) binding domain of APRIL serves as a platform for ligand multimerization and cross-linking. FASEB J (2009) 23:1584-95. doi:10.1096/fj.08-124669.
-
(2009)
FASEB J
, vol.23
, pp. 1584-1595
-
-
Kimberley, F.C.1
van Bostelen, L.2
Cameron, K.3
Hardenberg, G.4
Marquart, J.A.5
Hahne, M.6
-
19
-
-
20844432040
-
Identification of proteoglycans as the APRIL-specific binding partners
-
doi:10.1084/jem.20042309
-
Ingold K, Zumsteg A, Tardivel A, Huard B, Steiner QG, Cachero TG, et al. Identification of proteoglycans as the APRIL-specific binding partners. J Exp Med (2005) 201:1375-83. doi:10.1084/jem.20042309.
-
(2005)
J Exp Med
, vol.201
, pp. 1375-1383
-
-
Ingold, K.1
Zumsteg, A.2
Tardivel, A.3
Huard, B.4
Steiner, Q.G.5
Cachero, T.G.6
-
20
-
-
0037108490
-
BLyS and APRIL form biologically active heterotrimers that are expressed in patients with systemic immune-based rheumatic diseases
-
Roschke V, Sosnovtseva S, Ward CD, Hong JS, Smith R, Albert V, et al. BLyS and APRIL form biologically active heterotrimers that are expressed in patients with systemic immune-based rheumatic diseases. J Immunol (2002) 169:4314-21.
-
(2002)
J Immunol
, vol.169
, pp. 4314-4321
-
-
Roschke, V.1
Sosnovtseva, S.2
Ward, C.D.3
Hong, J.S.4
Smith, R.5
Albert, V.6
-
21
-
-
67649853099
-
Cracking the BAFF code. Nature reviews
-
doi:10.1038/nri2572
-
Mackay F, Schneider P. Cracking the BAFF code. Nature reviews. Immunology (2009) 9:491-502. doi:10.1038/nri2572.
-
(2009)
Immunology
, vol.9
, pp. 491-502
-
-
Mackay, F.1
Schneider, P.2
-
22
-
-
33744944082
-
Interactions of tumor necrosis factor (TNF) and TNF receptor family members in the mouse and human
-
doi:10.1074/jbc.M601553200
-
Bossen C, Ingold K, Tardivel A, Bodmer JL, Gaide O, Hertig S, et al. Interactions of tumor necrosis factor (TNF) and TNF receptor family members in the mouse and human. J Biol Chem (2006) 281:13964-71. doi:10.1074/jbc.M601553200.
-
(2006)
J Biol Chem
, vol.281
, pp. 13964-13971
-
-
Bossen, C.1
Ingold, K.2
Tardivel, A.3
Bodmer, J.L.4
Gaide, O.5
Hertig, S.6
-
23
-
-
84882769645
-
Identify the key amino acid of BAFF binding with TACI
-
doi:10.1016/j.cellimm.2013.06.003
-
Wang R, Wang R, Ma N, Guo Y, Xiao H, Chen G, et al. Identify the key amino acid of BAFF binding with TACI. Cell Immunol (2013) 284:84-90. doi:10.1016/j.cellimm.2013.06.003.
-
(2013)
Cell Immunol
, vol.284
, pp. 84-90
-
-
Wang, R.1
Wang, R.2
Ma, N.3
Guo, Y.4
Xiao, H.5
Chen, G.6
-
24
-
-
3142671331
-
B cell-activating factor belonging to the TNF family (BAFF)-R is the principal BAFF receptor facilitating BAFF costimulation of circulating T and B cells
-
Ng LG, Sutherland AP, Newton R, Qian F, Cachero TG, Scott ML, et al. B cell-activating factor belonging to the TNF family (BAFF)-R is the principal BAFF receptor facilitating BAFF costimulation of circulating T and B cells. J Immunol (2004) 173:807-17.
-
(2004)
J Immunol
, vol.173
, pp. 807-817
-
-
Ng, L.G.1
Sutherland, A.P.2
Newton, R.3
Qian, F.4
Cachero, T.G.5
Scott, M.L.6
-
25
-
-
38849104447
-
Regulated expression of BAFF-binding receptors during human B cell differentiation
-
Darce JR, Arendt BK, Wu X, Jelinek DF. Regulated expression of BAFF-binding receptors during human B cell differentiation. J Immunol (2007) 179:7276-86.
-
(2007)
J Immunol
, vol.179
, pp. 7276-7286
-
-
Darce, J.R.1
Arendt, B.K.2
Wu, X.3
Jelinek, D.F.4
-
26
-
-
7244223338
-
BAFF binding to T cell-expressed BAFF-R costimulates T cell proliferation and alloresponses
-
doi:10.1002/eji.200425198
-
Ye Q, Wang L, Wells AD, Tao R, Han R, Davidson A, et al. BAFF binding to T cell-expressed BAFF-R costimulates T cell proliferation and alloresponses. Eur J Immunol (2004) 34:2750-9. doi:10.1002/eji.200425198.
-
(2004)
Eur J Immunol
, vol.34
, pp. 2750-2759
-
-
Ye, Q.1
Wang, L.2
Wells, A.D.3
Tao, R.4
Han, R.5
Davidson, A.6
-
27
-
-
47249112106
-
B lymphocyte stimulator regulates adaptive immune responses by directly promoting dendritic cell maturation
-
Chang SK, Mihalcik SA, Jelinek DF. B lymphocyte stimulator regulates adaptive immune responses by directly promoting dendritic cell maturation. J Immunol (2008) 180:7394-403.
-
(2008)
J Immunol
, vol.180
, pp. 7394-7403
-
-
Chang, S.K.1
Mihalcik, S.A.2
Jelinek, D.F.3
-
28
-
-
33750616721
-
A role for BLyS in the activation of innate immune cells
-
doi:10.1182/blood-2005-12-017319
-
Chang SK, Arendt BK, Darce JR, Wu X, Jelinek DF. A role for BLyS in the activation of innate immune cells. Blood (2006) 108:2687-94. doi:10.1182/blood-2005-12-017319.
-
(2006)
Blood
, vol.108
, pp. 2687-2694
-
-
Chang, S.K.1
Arendt, B.K.2
Darce, J.R.3
Wu, X.4
Jelinek, D.F.5
-
29
-
-
0034600787
-
TACI is a TRAF-interacting receptor for TALL-1, a tumor necrosis factor family member involved in B cell regulation
-
doi:10.1084/jem.192.1.137
-
Xia XZ, Treanor J, Senaldi G, Khare SD, Boone T, Kelley M, et al. TACI is a TRAF-interacting receptor for TALL-1, a tumor necrosis factor family member involved in B cell regulation. J Exp Med (2000) 192:137-43. doi:10.1084/jem.192.1.137.
-
(2000)
J Exp Med
, vol.192
, pp. 137-143
-
-
Xia, X.Z.1
Treanor, J.2
Senaldi, G.3
Khare, S.D.4
Boone, T.5
Kelley, M.6
-
30
-
-
0039792391
-
NF-AT activation induced by a CAML-interacting member of the tumor necrosis factor receptor superfamily
-
doi:10.1126/science.278.5335.138
-
von Bulow GU, Bram RJ. NF-AT activation induced by a CAML-interacting member of the tumor necrosis factor receptor superfamily. Science (1997) 278:138-41. doi:10.1126/science.278.5335.138.
-
(1997)
Science
, vol.278
, pp. 138-141
-
-
von Bulow, G.U.1
Bram, R.J.2
-
31
-
-
0034254525
-
TNF receptor family member BCMA (B cell maturation) associates with TNF receptor-associated factor (TRAF) 1, TRAF2, and TRAF3 and activates NF-kappa B, elk-1, c-Jun N-terminal kinase, and p38 mitogen-activated protein kinase
-
Hatzoglou A, Roussel J, Bourgeade MF, Rogier E, Madry C, Inoue J, et al. TNF receptor family member BCMA (B cell maturation) associates with TNF receptor-associated factor (TRAF) 1, TRAF2, and TRAF3 and activates NF-kappa B, elk-1, c-Jun N-terminal kinase, and p38 mitogen-activated protein kinase. J Immunol (2000) 165:1322-30.
-
(2000)
J Immunol
, vol.165
, pp. 1322-1330
-
-
Hatzoglou, A.1
Roussel, J.2
Bourgeade, M.F.3
Rogier, E.4
Madry, C.5
Inoue, J.6
-
32
-
-
15444379092
-
An atypical tumor necrosis factor (TNF) receptor-associated factor-binding motif of B cell-activating factor belonging to the TNF family (BAFF) receptor mediates induction of the noncanonical NF-kappaB signaling pathway
-
doi:10.1074/jbc.M413634200
-
Morrison MD, Reiley W, Zhang M, Sun SC. An atypical tumor necrosis factor (TNF) receptor-associated factor-binding motif of B cell-activating factor belonging to the TNF family (BAFF) receptor mediates induction of the noncanonical NF-kappaB signaling pathway. J Biol Chem (2005) 280:10018-24. doi:10.1074/jbc.M413634200.
-
(2005)
J Biol Chem
, vol.280
, pp. 10018-10024
-
-
Morrison, M.D.1
Reiley, W.2
Zhang, M.3
Sun, S.C.4
-
33
-
-
2942731516
-
Regulation of the NF-kappaB-inducing kinase by tumor necrosis factor receptor-associated factor 3-induced degradation
-
doi:10.1074/jbc.M403286200
-
Liao G, Zhang M, Harhaj EW, Sun SC. Regulation of the NF-kappaB-inducing kinase by tumor necrosis factor receptor-associated factor 3-induced degradation. J Biol Chem (2004) 279:26243-50. doi:10.1074/jbc.M403286200.
-
(2004)
J Biol Chem
, vol.279
, pp. 26243-26250
-
-
Liao, G.1
Zhang, M.2
Harhaj, E.W.3
Sun, S.C.4
-
34
-
-
44949240664
-
cIAP1 and cIAP2 facilitate cancer cell survival by functioning as E3 ligases that promote RIP1 ubiquitination
-
doi:10.1016/j.molcel.2008.05.014
-
Bertrand MJ, Milutinovic S, Dickson KM, Ho WC, Boudreault A, Durkin J, et al. cIAP1 and cIAP2 facilitate cancer cell survival by functioning as E3 ligases that promote RIP1 ubiquitination. Mol Cell (2008) 30:689-700. doi:10.1016/j.molcel.2008.05.014.
-
(2008)
Mol Cell
, vol.30
, pp. 689-700
-
-
Bertrand, M.J.1
Milutinovic, S.2
Dickson, K.M.3
Ho, W.C.4
Boudreault, A.5
Durkin, J.6
-
35
-
-
58249086500
-
Ubiquitin binding modulates IAP antagonist-stimulated proteasomal degradation of c-IAP1 and c-IAP2(1)
-
doi:10.1042/BJ20081885
-
Blankenship JW, Varfolomeev E, Goncharov T, Fedorova AV, Kirkpatrick DS, Izrael-Tomasevic A, et al. Ubiquitin binding modulates IAP antagonist-stimulated proteasomal degradation of c-IAP1 and c-IAP2(1). Biochem J (2009) 417:149-60. doi:10.1042/BJ20081885.
-
(2009)
Biochem J
, vol.417
, pp. 149-160
-
-
Blankenship, J.W.1
Varfolomeev, E.2
Goncharov, T.3
Fedorova, A.V.4
Kirkpatrick, D.S.5
Izrael-Tomasevic, A.6
-
36
-
-
1542380581
-
Ubiquitination and translocation of TRAF2 is required for activation of JNK but not of p38 or NF-kappaB
-
doi:10.1038/sj.emboj.7600044
-
Habelhah H, Takahashi S, Cho SG, Kadoya T, Watanabe T, Ronai Z. Ubiquitination and translocation of TRAF2 is required for activation of JNK but not of p38 or NF-kappaB. EMBO J (2004) 23:322-32. doi:10.1038/sj.emboj.7600044.
-
(2004)
EMBO J
, vol.23
, pp. 322-332
-
-
Habelhah, H.1
Takahashi, S.2
Cho, S.G.3
Kadoya, T.4
Watanabe, T.5
Ronai, Z.6
-
37
-
-
74049136127
-
Different modes of ubiquitination of the adaptor TRAF3 selectively activate the expression of type I interferons and proinflammatory cytokines
-
doi:10.1038/ni.1819
-
Tseng PH, Matsuzawa A, Zhang W, Mino T, Vignali DA, Karin M. Different modes of ubiquitination of the adaptor TRAF3 selectively activate the expression of type I interferons and proinflammatory cytokines. Nat Immunol (2010) 11:70-5. doi:10.1038/ni.1819.
-
(2010)
Nat Immunol
, vol.11
, pp. 70-75
-
-
Tseng, P.H.1
Matsuzawa, A.2
Zhang, W.3
Mino, T.4
Vignali, D.A.5
Karin, M.6
-
38
-
-
36048999753
-
IAP antagonists induce autoubiquitination of c-IAPs, NF-kappaB activation, and TNFalpha-dependent apoptosis
-
doi:10.1016/j.cell.2007.10.030
-
Varfolomeev E, Blankenship JW, Wayson SM, Fedorova AV, Kayagaki N, Garg P, et al. IAP antagonists induce autoubiquitination of c-IAPs, NF-kappaB activation, and TNFalpha-dependent apoptosis. Cell (2007) 131:669-81. doi:10.1016/j.cell.2007.10.030.
-
(2007)
Cell
, vol.131
, pp. 669-681
-
-
Varfolomeev, E.1
Blankenship, J.W.2
Wayson, S.M.3
Fedorova, A.V.4
Kayagaki, N.5
Garg, P.6
-
39
-
-
36148954336
-
, IAP antagonists target cIAP1 to induce TNFalpha-dependent apoptosis
-
doi:10.1016/j.cell.2007.10.037
-
Vince JE, Wong WW, Khan N, Feltham R, Chau D, Ahmed AU, et al. , IAP antagonists target cIAP1 to induce TNFalpha-dependent apoptosis. Cell (2007) 131:682-93. doi:10.1016/j.cell.2007.10.037.
-
(2007)
Cell
, vol.131
, pp. 682-693
-
-
Vince, J.E.1
Wong, W.W.2
Khan, N.3
Feltham, R.4
Chau, D.5
Ahmed, A.U.6
-
40
-
-
56349164232
-
Nonredundant and complementary functions of TRAF2 and TRAF3 in a ubiquitination cascade that activates NIK-dependent alternative NF-kappaB signaling
-
doi:10.1038/ni.1678
-
Vallabhapurapu S, Matsuzawa A, Zhang W, Tseng PH, Keats JJ, Wang H, et al. Nonredundant and complementary functions of TRAF2 and TRAF3 in a ubiquitination cascade that activates NIK-dependent alternative NF-kappaB signaling. Nat Immunol (2008) 9:1364-70. doi:10.1038/ni.1678.
-
(2008)
Nat Immunol
, vol.9
, pp. 1364-1370
-
-
Vallabhapurapu, S.1
Matsuzawa, A.2
Zhang, W.3
Tseng, P.H.4
Keats, J.J.5
Wang, H.6
-
41
-
-
56349164239
-
Noncanonical NF-kappaB activation requires coordinated assembly of a regulatory complex of the adaptors cIAP1, cIAP2, TRAF2 and TRAF3 and the kinase NIK
-
doi:10.1038/ni.1676
-
Zarnegar BJ, Wang Y, Mahoney DJ, Dempsey PW, Cheung HH, He J, et al. Noncanonical NF-kappaB activation requires coordinated assembly of a regulatory complex of the adaptors cIAP1, cIAP2, TRAF2 and TRAF3 and the kinase NIK. Nat Immunol (2008) 9:1371-8. doi:10.1038/ni.1676.
-
(2008)
Nat Immunol
, vol.9
, pp. 1371-1378
-
-
Zarnegar, B.J.1
Wang, Y.2
Mahoney, D.J.3
Dempsey, P.W.4
Cheung, H.H.5
He, J.6
-
42
-
-
10344226678
-
Key molecular contacts promote recognition of the BAFF receptor by TNF receptor-associated factor 3: implications for intracellular signaling regulation
-
Ni CZ, Oganesyan G, Welsh K, Zhu X, Reed JC, Satterthwait AC, et al. Key molecular contacts promote recognition of the BAFF receptor by TNF receptor-associated factor 3: implications for intracellular signaling regulation. J Immunol (2004) 173:7394-400.
-
(2004)
J Immunol
, vol.173
, pp. 7394-7400
-
-
Ni, C.Z.1
Oganesyan, G.2
Welsh, K.3
Zhu, X.4
Reed, J.C.5
Satterthwait, A.C.6
-
43
-
-
40249115896
-
TRAF2 and TRAF3 signal adapters act cooperatively to control the maturation and survival signals delivered to B cells by the BAFF receptor
-
doi:10.1016/j.immuni.2008.01.009
-
Gardam S, Sierro F, Basten A, Mackay F, Brink R. TRAF2 and TRAF3 signal adapters act cooperatively to control the maturation and survival signals delivered to B cells by the BAFF receptor. Immunity (2008) 28:391-401. doi:10.1016/j.immuni.2008.01.009.
-
(2008)
Immunity
, vol.28
, pp. 391-401
-
-
Gardam, S.1
Sierro, F.2
Basten, A.3
Mackay, F.4
Brink, R.5
-
44
-
-
0038771214
-
Modulation of NF-kappa B activity by exchange of dimers
-
doi:10.1016/S1097-2765(03)00227-2
-
Saccani S, Pantano S, Natoli G. Modulation of NF-kappa B activity by exchange of dimers. Mol Cell (2003) 11:1563-74. doi:10.1016/S1097-2765(03)00227-2.
-
(2003)
Mol Cell
, vol.11
, pp. 1563-1574
-
-
Saccani, S.1
Pantano, S.2
Natoli, G.3
-
45
-
-
0031714501
-
Molecular determinants of NF-kappaB-inducing kinase action
-
Lin X, Mu Y, Cunningham ET Jr, Marcu KB, Geleziunas R, Greene WC. Molecular determinants of NF-kappaB-inducing kinase action. Mol Cell Biol (1998) 18:5899-907.
-
(1998)
Mol Cell Biol
, vol.18
, pp. 5899-5907
-
-
Lin, X.1
Mu, Y.2
Cunningham Jr., E.T.3
Marcu, K.B.4
Geleziunas, R.5
Greene, W.C.6
-
46
-
-
84867339398
-
The crystal structure of the catalytic domain of the NF-kappaB inducing kinase reveals a narrow but flexible active site
-
doi:10.1016/j.str.2012.07.013
-
de Leon-Boenig G, Bowman KK, Feng JA, Crawford T, Everett C, Franke Y, et al. The crystal structure of the catalytic domain of the NF-kappaB inducing kinase reveals a narrow but flexible active site. Structure (2012) 20:1704-14. doi:10.1016/j.str.2012.07.013.
-
(2012)
Structure
, vol.20
, pp. 1704-1714
-
-
de Leon-Boenig, G.1
Bowman, K.K.2
Feng, J.A.3
Crawford, T.4
Everett, C.5
Franke, Y.6
-
47
-
-
0032583947
-
NF-kappaB-inducing kinase activates IKK-alpha by phosphorylation of Ser-176
-
doi:10.1073/pnas.95.7.3792
-
Ling L, Cao Z, Goeddel DV. NF-kappaB-inducing kinase activates IKK-alpha by phosphorylation of Ser-176. Proc Natl Acad Sci U S A (1998) 95:3792-7. doi:10.1073/pnas.95.7.3792.
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 3792-3797
-
-
Ling, L.1
Cao, Z.2
Goeddel, D.V.3
-
48
-
-
33646336615
-
beta-TrCP binding and processing of NF-kappaB2/p100 involve its phosphorylation at serines 866 and 870
-
doi:10.1016/j.cellsig.2005.10.011
-
Liang C, Zhang M, Sun SC. beta-TrCP binding and processing of NF-kappaB2/p100 involve its phosphorylation at serines 866 and 870. Cell Signal (2006) 18:1309-17. doi:10.1016/j.cellsig.2005.10.011.
-
(2006)
Cell Signal
, vol.18
, pp. 1309-1317
-
-
Liang, C.1
Zhang, M.2
Sun, S.C.3
-
49
-
-
3142663912
-
Induction of p100 processing by NF-kappaB-inducing kinase involves docking IkappaB kinase alpha (IKKalpha) to p100 and IKKalpha-mediated phosphorylation
-
doi:10.1074/jbc.M401428200
-
Xiao G, Fong A, Sun SC. Induction of p100 processing by NF-kappaB-inducing kinase involves docking IkappaB kinase alpha (IKKalpha) to p100 and IKKalpha-mediated phosphorylation. J Biol Chem (2004) 279:30099-105. doi:10.1074/jbc.M401428200.
-
(2004)
J Biol Chem
, vol.279
, pp. 30099-30105
-
-
Xiao, G.1
Fong, A.2
Sun, S.C.3
-
50
-
-
0037151118
-
Genetic evidence for the essential role of beta-transducin repeat-containing protein in the inducible processing of NF-kappa B2/p100
-
doi:10.1074/jbc.C200151200
-
Fong A, Sun SC. Genetic evidence for the essential role of beta-transducin repeat-containing protein in the inducible processing of NF-kappa B2/p100. J Biol Chem (2002) 277:22111-4. doi:10.1074/jbc.C200151200.
-
(2002)
J Biol Chem
, vol.277
, pp. 22111-22114
-
-
Fong, A.1
Sun, S.C.2
-
51
-
-
70349459622
-
TNF receptor-associated factor 1 is a positive regulator of the NF-kappaB alternative pathway
-
doi:10.1016/j.molimm.2009.07.029
-
Lavorgna A, De Filippi R, Formisano S, Leonardi A. TNF receptor-associated factor 1 is a positive regulator of the NF-kappaB alternative pathway. Mol Immunol (2009) 46:3278-82. doi:10.1016/j.molimm.2009.07.029.
-
(2009)
Mol Immunol
, vol.46
, pp. 3278-3282
-
-
Lavorgna, A.1
De Filippi, R.2
Formisano, S.3
Leonardi, A.4
-
52
-
-
77950352082
-
Crystal structures of the TRAF2: cIAP2 and the TRAF1: TRAF2: cIAP2 complexes: affinity, specificity, and regulation
-
doi:10.1016/j.molcel.2010.03.009
-
Zheng C, Kabaleeswaran V, Wang Y, Cheng G, Wu H. Crystal structures of the TRAF2: cIAP2 and the TRAF1: TRAF2: cIAP2 complexes: affinity, specificity, and regulation. Mol Cell (2010) 38:101-13. doi:10.1016/j.molcel.2010.03.009.
-
(2010)
Mol Cell
, vol.38
, pp. 101-113
-
-
Zheng, C.1
Kabaleeswaran, V.2
Wang, Y.3
Cheng, G.4
Wu, H.5
-
53
-
-
84877882474
-
Inducible tumor necrosis factor (TNF) receptor-associated factor-1 expression couples the canonical to the non-canonical NF-kappaB pathway in TNF stimulation
-
doi:10.1074/jbc.M113.464081
-
Choudhary S, Kalita M, Fang L, Patel KV, Tian B, Zhao Y, et al. Inducible tumor necrosis factor (TNF) receptor-associated factor-1 expression couples the canonical to the non-canonical NF-kappaB pathway in TNF stimulation. J Biol Chem (2013) 288:14612-23. doi:10.1074/jbc.M113.464081.
-
(2013)
J Biol Chem
, vol.288
, pp. 14612-14623
-
-
Choudhary, S.1
Kalita, M.2
Fang, L.3
Patel, K.V.4
Tian, B.5
Zhao, Y.6
-
54
-
-
73349113225
-
Differential requirement of MALT1 for BAFF-induced outcomes in B cell subsets
-
doi:10.1084/jem.20091802
-
Tusche MW, Ward LA, Vu F, McCarthy D, Quintela-Fandino M, Ruland J, et al. Differential requirement of MALT1 for BAFF-induced outcomes in B cell subsets. J Exp Med (2009) 206:2671-83. doi:10.1084/jem.20091802.
-
(2009)
J Exp Med
, vol.206
, pp. 2671-2683
-
-
Tusche, M.W.1
Ward, L.A.2
Vu, F.3
McCarthy, D.4
Quintela-Fandino, M.5
Ruland, J.6
-
55
-
-
77958086967
-
Lipopolysaccharide-induced activation of NF-kappaB non-canonical pathway requires BCL10 serine 138 and NIK phosphorylations
-
doi:10.1016/j.yexcr.2010.05.004
-
Bhattacharyya S, Borthakur A, Dudeja PK, Tobacman JK. Lipopolysaccharide-induced activation of NF-kappaB non-canonical pathway requires BCL10 serine 138 and NIK phosphorylations. Exp Cell Res (2010) 316:3317-27. doi:10.1016/j.yexcr.2010.05.004.
-
(2010)
Exp Cell Res
, vol.316
, pp. 3317-3327
-
-
Bhattacharyya, S.1
Borthakur, A.2
Dudeja, P.K.3
Tobacman, J.K.4
-
56
-
-
77950538241
-
Emu-BCL10 mice exhibit constitutive activation of both canonical and noncanonical NF-kappaB pathways generating marginal zone (MZ) B-cell expansion as a precursor to splenic MZ lymphoma
-
doi:10.1182/blood-2008-12-192583
-
Li Z, Wang H, Xue L, Shin DM, Roopenian D, Xu W, et al. Emu-BCL10 mice exhibit constitutive activation of both canonical and noncanonical NF-kappaB pathways generating marginal zone (MZ) B-cell expansion as a precursor to splenic MZ lymphoma. Blood (2009) 114:4158-68. doi:10.1182/blood-2008-12-192583.
-
(2009)
Blood
, vol.114
, pp. 4158-4168
-
-
Li, Z.1
Wang, H.2
Xue, L.3
Shin, D.M.4
Roopenian, D.5
Xu, W.6
-
57
-
-
84869825522
-
Critical role of B cell lymphoma 10 in BAFF-regulated NF-kappaB activation and survival of anergic B cells
-
doi:10.4049/jimmunol.1102952
-
Yu M, Chen Y, He Y, Podd A, Fu G, Wright JA, et al. Critical role of B cell lymphoma 10 in BAFF-regulated NF-kappaB activation and survival of anergic B cells. J Immunol (2012) 189:5185-93. doi:10.4049/jimmunol.1102952.
-
(2012)
J Immunol
, vol.189
, pp. 5185-5193
-
-
Yu, M.1
Chen, Y.2
He, Y.3
Podd, A.4
Fu, G.5
Wright, J.A.6
-
58
-
-
84859430011
-
Fbxw7alpha-and GSK3-mediated degradation of p100 is a pro-survival mechanism in multiple myeloma
-
doi:10.1038/ncb2463
-
Busino L, Millman SE, Scotto L, Kyratsous CA, Basrur V, O'Connor O, et al. Fbxw7alpha-and GSK3-mediated degradation of p100 is a pro-survival mechanism in multiple myeloma. Nat Cell Biol (2012) 14:375-85. doi:10.1038/ncb2463.
-
(2012)
Nat Cell Biol
, vol.14
, pp. 375-385
-
-
Busino, L.1
Millman, S.E.2
Scotto, L.3
Kyratsous, C.A.4
Basrur, V.5
O'Connor, O.6
-
59
-
-
84861668632
-
SCF(Fbw7) modulates the NFkB signaling pathway by targeting NFkB2 for ubiquitination and destruction
-
doi:10.1016/j.celrep.2012.04.002
-
Fukushima H, Matsumoto A, Inuzuka H, Zhai B, Lau AW, Wan L, et al. SCF(Fbw7) modulates the NFkB signaling pathway by targeting NFkB2 for ubiquitination and destruction. Cell Rep (2012) 1:434-43. doi:10.1016/j.celrep.2012.04.002.
-
(2012)
Cell Rep
, vol.1
, pp. 434-443
-
-
Fukushima, H.1
Matsumoto, A.2
Inuzuka, H.3
Zhai, B.4
Lau, A.W.5
Wan, L.6
-
60
-
-
84874193578
-
OTUD7B controls non-canonical NF-kappaB activation through deubiquitination of TRAF3
-
doi:10.1038/nature11831
-
Hu H, Brittain GC, Chang JH, Puebla-Osorio N, Jin J, Zal A, et al. OTUD7B controls non-canonical NF-kappaB activation through deubiquitination of TRAF3. Nature (2013) 494:371-4. doi:10.1038/nature11831.
-
(2013)
Nature
, vol.494
, pp. 371-374
-
-
Hu, H.1
Brittain, G.C.2
Chang, J.H.3
Puebla-Osorio, N.4
Jin, J.5
Zal, A.6
-
61
-
-
5644271413
-
Act1, a negative regulator in CD40-and BAFF-mediated B cell survival
-
doi:10.1016/j.immuni.2004.09.001
-
Qian Y, Qin J, Cui G, Naramura M, Snow EC, Ware CF, et al. Act1, a negative regulator in CD40-and BAFF-mediated B cell survival. Immunity (2004) 21:575-87. doi:10.1016/j.immuni.2004.09.001.
-
(2004)
Immunity
, vol.21
, pp. 575-587
-
-
Qian, Y.1
Qin, J.2
Cui, G.3
Naramura, M.4
Snow, E.C.5
Ware, C.F.6
-
62
-
-
77953824286
-
Negative feedback in noncanonical NF-kappaB signaling modulates NIK stability through IKKalpha-mediated phosphorylation
-
doi:10.1126/scisignal.2000778
-
Razani B, Zarnegar B, Ytterberg AJ, Shiba T, Dempsey PW, Ware CF, et al. Negative feedback in noncanonical NF-kappaB signaling modulates NIK stability through IKKalpha-mediated phosphorylation. Sci Signal (2010) 3:ra41. doi:10.1126/scisignal.2000778.
-
(2010)
Sci Signal
, vol.3
-
-
Razani, B.1
Zarnegar, B.2
Ytterberg, A.J.3
Shiba, T.4
Dempsey, P.W.5
Ware, C.F.6
-
63
-
-
84858735072
-
The noncanonical NF-kappaB pathway
-
doi:10.1111/j.1600-065X.2011.01088.x
-
Sun SC. The noncanonical NF-kappaB pathway. Immunol Rev (2012) 246:125-40. doi:10.1111/j.1600-065X.2011.01088.x.
-
(2012)
Immunol Rev
, vol.246
, pp. 125-140
-
-
Sun, S.C.1
-
64
-
-
17944375043
-
TACI-Ig neutralizes molecules critical for B cell development and autoimmune disease. impaired B cell maturation in mice lacking BLyS
-
doi:10.1016/S1074-7613(01)00183-2
-
Gross JA, Dillon SR, Mudri S, Johnston J, Littau A, Roque R, et al. TACI-Ig neutralizes molecules critical for B cell development and autoimmune disease. impaired B cell maturation in mice lacking BLyS. Immunity (2001) 15:289-302. doi:10.1016/S1074-7613(01)00183-2.
-
(2001)
Immunity
, vol.15
, pp. 289-302
-
-
Gross, J.A.1
Dillon, S.R.2
Mudri, S.3
Johnston, J.4
Littau, A.5
Roque, R.6
-
65
-
-
0035860559
-
An essential role for BAFF in the normal development of B cells through a BCMA-independent pathway
-
doi:10.1126/science.1061964
-
Schiemann B, Gommerman JL, Vora K, Cachero TG, Shulga-Morskaya S, Dobles M, et al. An essential role for BAFF in the normal development of B cells through a BCMA-independent pathway. Science (2001) 293:2111-4. doi:10.1126/science.1061964.
-
(2001)
Science
, vol.293
, pp. 2111-2114
-
-
Schiemann, B.1
Gommerman, J.L.2
Vora, K.3
Cachero, T.G.4
Shulga-Morskaya, S.5
Dobles, M.6
-
66
-
-
4043075603
-
TNF family member B cell-activating factor (BAFF) receptor-dependent and-independent roles for BAFF in B cell physiology
-
Sasaki Y, Casola S, Kutok JL, Rajewsky K, Schmidt-Supprian M. TNF family member B cell-activating factor (BAFF) receptor-dependent and-independent roles for BAFF in B cell physiology. J Immunol (2004) 173:2245-52.
-
(2004)
J Immunol
, vol.173
, pp. 2245-2252
-
-
Sasaki, Y.1
Casola, S.2
Kutok, J.L.3
Rajewsky, K.4
Schmidt-Supprian, M.5
-
67
-
-
4043146475
-
B cell-activating factor belonging to the TNF family acts through separate receptors to support B cell survival and T cell-independent antibody formation
-
Shulga-Morskaya S, Dobles M, Walsh ME, Ng LG, MacKay F, Rao SP, et al. B cell-activating factor belonging to the TNF family acts through separate receptors to support B cell survival and T cell-independent antibody formation. J Immunol (2004) 173:2331-41.
-
(2004)
J Immunol
, vol.173
, pp. 2331-2341
-
-
Shulga-Morskaya, S.1
Dobles, M.2
Walsh, M.E.3
Ng, L.G.4
MacKay, F.5
Rao, S.P.6
-
68
-
-
0035860466
-
BAFF-R, a newly identified TNF receptor that specifically interacts with BAFF
-
doi:10.1126/science.1061965
-
Thompson JS, Bixler SA, Qian F, Vora K, Scott ML, Cachero TG, et al. BAFF-R, a newly identified TNF receptor that specifically interacts with BAFF. Science (2001) 293:2108-11. doi:10.1126/science.1061965.
-
(2001)
Science
, vol.293
, pp. 2108-2111
-
-
Thompson, J.S.1
Bixler, S.A.2
Qian, F.3
Vora, K.4
Scott, M.L.5
Cachero, T.G.6
-
69
-
-
0035797908
-
Identification of a novel receptor for B lymphocyte stimulator that is mutated in a mouse strain with severe B cell deficiency
-
doi:10.1016/S0960-9822(01)00481-X
-
Yan M, Brady JR, Chan B, Lee WP, Hsu B, Harless S, et al. Identification of a novel receptor for B lymphocyte stimulator that is mutated in a mouse strain with severe B cell deficiency. Curr Biol (2001) 11:1547-52. doi:10.1016/S0960-9822(01)00481-X.
-
(2001)
Curr Biol
, vol.11
, pp. 1547-1552
-
-
Yan, M.1
Brady, J.R.2
Chan, B.3
Lee, W.P.4
Hsu, B.5
Harless, S.6
-
70
-
-
12944249540
-
Severe B cell hyperplasia and autoimmune disease in TALL-1 transgenic mice
-
doi:10.1073/pnas.97.7.3370
-
Khare SD, Sarosi I, Xia XZ, McCabe S, Miner K, Solovyev I, et al. Severe B cell hyperplasia and autoimmune disease in TALL-1 transgenic mice. Proc Natl Acad Sci U S A (2000) 97:3370-5. doi:10.1073/pnas.97.7.3370.
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, pp. 3370-3375
-
-
Khare, S.D.1
Sarosi, I.2
Xia, X.Z.3
McCabe, S.4
Miner, K.5
Solovyev, I.6
-
71
-
-
0033428703
-
Mice transgenic for BAFF develop lymphocytic disorders along with autoimmune manifestations
-
doi:10.1084/jem.190.11.1697
-
Mackay F, Woodcock SA, Lawton P, Ambrose C, Baetscher M, Schneider P, et al. Mice transgenic for BAFF develop lymphocytic disorders along with autoimmune manifestations. J Exp Med (1999) 190:1697-710. doi:10.1084/jem.190.11.1697.
-
(1999)
J Exp Med
, vol.190
, pp. 1697-1710
-
-
Mackay, F.1
Woodcock, S.A.2
Lawton, P.3
Ambrose, C.4
Baetscher, M.5
Schneider, P.6
-
72
-
-
0035007222
-
B-cell maturation protein, which binds the tumor necrosis factor family members BAFF and APRIL, is dispensable for humoral immune responses
-
doi:10.1128/MCB.21.12.4067-4074.2001
-
Xu S, Lam KP. B-cell maturation protein, which binds the tumor necrosis factor family members BAFF and APRIL, is dispensable for humoral immune responses. Mol Cell Biol (2001) 21:4067-74. doi:10.1128/MCB.21.12.4067-4074.2001.
-
(2001)
Mol Cell Biol
, vol.21
, pp. 4067-4074
-
-
Xu, S.1
Lam, K.P.2
-
73
-
-
0035004320
-
Regulation of the T-independent humoral response by TACI
-
doi:10.1016/S1074-7613(01)00130-3
-
von Bulow GU, van Deursen JM, Bram RJ. Regulation of the T-independent humoral response by TACI. Immunity (2001) 14:573-82. doi:10.1016/S1074-7613(01)00130-3.
-
(2001)
Immunity
, vol.14
, pp. 573-582
-
-
von Bulow, G.U.1
van Deursen, J.M.2
Bram, R.J.3
-
74
-
-
0034919939
-
Activation and accumulation of B cells in TACI-deficient mice
-
doi:10.1038/89790
-
Yan M, Wang H, Chan B, Roose-Girma M, Erickson S, Baker T, et al. Activation and accumulation of B cells in TACI-deficient mice. Nat Immunol (2001) 2:638-43. doi:10.1038/89790.
-
(2001)
Nat Immunol
, vol.2
, pp. 638-643
-
-
Yan, M.1
Wang, H.2
Chan, B.3
Roose-Girma, M.4
Erickson, S.5
Baker, T.6
-
75
-
-
2942518502
-
Excess BAFF rescues self-reactive B cells from peripheral deletion and allows them to enter forbidden follicular and marginal zone niches
-
doi:10.1016/j.immuni.2004.05.010
-
Thien M, Phan TG, Gardam S, Amesbury M, Basten A, Mackay F, et al. Excess BAFF rescues self-reactive B cells from peripheral deletion and allows them to enter forbidden follicular and marginal zone niches. Immunity (2004) 20:785-98. doi:10.1016/j.immuni.2004.05.010.
-
(2004)
Immunity
, vol.20
, pp. 785-798
-
-
Thien, M.1
Phan, T.G.2
Gardam, S.3
Amesbury, M.4
Basten, A.5
Mackay, F.6
-
76
-
-
1842633887
-
Reduced competitiveness of autoantigen-engaged B cells due to increased dependence on BAFF
-
doi:10.1016/S1074-7613(04)00079-2
-
Lesley R, Xu Y, Kalled SL, Hess DM, Schwab SR, Shu HB, et al. Reduced competitiveness of autoantigen-engaged B cells due to increased dependence on BAFF. Immunity (2004) 20:441-53. doi:10.1016/S1074-7613(04)00079-2.
-
(2004)
Immunity
, vol.20
, pp. 441-453
-
-
Lesley, R.1
Xu, Y.2
Kalled, S.L.3
Hess, D.M.4
Schwab, S.R.5
Shu, H.B.6
-
77
-
-
0031985287
-
Nuclear factor (NF)-kappa B2 (p100/p52) is required for normal splenic microarchitecture and B cell-mediated immune responses
-
doi:10.1084/jem.187.2.185
-
Caamano JH, Rizzo CA, Durham SK, Barton DS, Raventos-Suarez C, Snapper CM, et al. Nuclear factor (NF)-kappa B2 (p100/p52) is required for normal splenic microarchitecture and B cell-mediated immune responses. J Exp Med (1998) 187:185-96. doi:10.1084/jem.187.2.185.
-
(1998)
J Exp Med
, vol.187
, pp. 185-196
-
-
Caamano, J.H.1
Rizzo, C.A.2
Durham, S.K.3
Barton, D.S.4
Raventos-Suarez, C.5
Snapper, C.M.6
-
78
-
-
0031964855
-
Mice deficient in nuclear factor (NF)-kappa B/p52 present with defects in humoral responses, germinal center reactions, and splenic microarchitecture
-
doi:10.1084/jem.187.2.147
-
Franzoso G, Carlson L, Poljak L, Shores EW, Epstein S, Leonardi A, et al. Mice deficient in nuclear factor (NF)-kappa B/p52 present with defects in humoral responses, germinal center reactions, and splenic microarchitecture. J Exp Med (1998) 187:147-59. doi:10.1084/jem.187.2.147.
-
(1998)
J Exp Med
, vol.187
, pp. 147-159
-
-
Franzoso, G.1
Carlson, L.2
Poljak, L.3
Shores, E.W.4
Epstein, S.5
Leonardi, A.6
-
79
-
-
0036794398
-
BAFF-induced NEMO-independent processing of NF-kappa B2 in maturing B cells
-
doi:10.1038/ni842
-
Claudio E, Brown K, Park S, Wang H, Siebenlist U. BAFF-induced NEMO-independent processing of NF-kappa B2 in maturing B cells. Nat Immunol (2002) 3:958-65. doi:10.1038/ni842.
-
(2002)
Nat Immunol
, vol.3
, pp. 958-965
-
-
Claudio, E.1
Brown, K.2
Park, S.3
Wang, H.4
Siebenlist, U.5
-
80
-
-
15444357762
-
Requirement for NF-kappaB in osteoclast and B-cell development
-
doi:10.1101/gad.11.24.3482
-
Franzoso G, Carlson L, Xing L, Poljak L, Shores EW, Brown KD, et al. Requirement for NF-kappaB in osteoclast and B-cell development. Genes Dev (1997) 11:3482-96. doi:10.1101/gad.11.24.3482.
-
(1997)
Genes Dev
, vol.11
, pp. 3482-3496
-
-
Franzoso, G.1
Carlson, L.2
Xing, L.3
Poljak, L.4
Shores, E.W.5
Brown, K.D.6
-
81
-
-
0035936002
-
Transcription of the RelB gene is regulated by NF-kappaB
-
doi:10.1038/sj.onc.1204868
-
Bren GD, Solan NJ, Miyoshi H, Pennington KN, Pobst LJ, Paya CV. Transcription of the RelB gene is regulated by NF-kappaB. Oncogene (2001) 20:7722-33. doi:10.1038/sj.onc.1204868.
-
(2001)
Oncogene
, vol.20
, pp. 7722-7733
-
-
Bren, G.D.1
Solan, N.J.2
Miyoshi, H.3
Pennington, K.N.4
Pobst, L.J.5
Paya, C.V.6
-
82
-
-
0037931474
-
RelB/p50 dimers are differentially regulated by tumor necrosis factor-alpha and lymphotoxin-beta receptor activation: critical roles for p100
-
doi:10.1074/jbc.M300106200
-
Derudder E, Dejardin E, Pritchard LL, Green DR, Korner M, Baud V. RelB/p50 dimers are differentially regulated by tumor necrosis factor-alpha and lymphotoxin-beta receptor activation: critical roles for p100. J Biol Chem (2003) 278:23278-84. doi:10.1074/jbc.M300106200.
-
(2003)
J Biol Chem
, vol.278
, pp. 23278-23284
-
-
Derudder, E.1
Dejardin, E.2
Pritchard, L.L.3
Green, D.R.4
Korner, M.5
Baud, V.6
-
83
-
-
0037413709
-
RelB is required for Peyer's patch development: differential regulation of p52-RelB by lymphotoxin and TNF
-
doi:10.1093/emboj/cdg004
-
Yilmaz ZB, Weih DS, Sivakumar V, Weih F. RelB is required for Peyer's patch development: differential regulation of p52-RelB by lymphotoxin and TNF. EMBO J (2003) 22:121-30. doi:10.1093/emboj/cdg004.
-
(2003)
EMBO J
, vol.22
, pp. 121-130
-
-
Yilmaz, Z.B.1
Weih, D.S.2
Sivakumar, V.3
Weih, F.4
-
84
-
-
56349091862
-
Tonic B cell antigen receptor signals supply an NF-kappaB substrate for prosurvival BLyS signaling
-
doi:10.1038/ni.1666
-
Stadanlick JE, Kaileh M, Karnell FG, Scholz JL, Miller JP, Quinn WJ III, et al. Tonic B cell antigen receptor signals supply an NF-kappaB substrate for prosurvival BLyS signaling. Nat Immunol (2008) 9:1379-87. doi:10.1038/ni.1666.
-
(2008)
Nat Immunol
, vol.9
, pp. 1379-1387
-
-
Stadanlick, J.E.1
Kaileh, M.2
Karnell, F.G.3
Scholz, J.L.4
Miller, J.P.5
Quinn III, W.J.6
-
85
-
-
33744989924
-
Canonical NF-kappaB activity, dispensable for B cell development, replaces BAFF-receptor signals and promotes B cell proliferation upon activation
-
doi:10.1016/j.immuni.2006.04.005
-
Sasaki Y, Derudder E, Hobeika E, Pelanda R, Reth M, Rajewsky K, et al. Canonical NF-kappaB activity, dispensable for B cell development, replaces BAFF-receptor signals and promotes B cell proliferation upon activation. Immunity (2006) 24:729-39. doi:10.1016/j.immuni.2006.04.005.
-
(2006)
Immunity
, vol.24
, pp. 729-739
-
-
Sasaki, Y.1
Derudder, E.2
Hobeika, E.3
Pelanda, R.4
Reth, M.5
Rajewsky, K.6
-
86
-
-
0035896422
-
Defective lymphotoxin-beta receptor-induced NF-kappaB transcriptional activity in NIK-deficient mice
-
doi:10.1126/science.1058453
-
Yin L, Wu L, Wesche H, Arthur CD, White JM, Goeddel DV, et al. Defective lymphotoxin-beta receptor-induced NF-kappaB transcriptional activity in NIK-deficient mice. Science (2001) 291:2162-5. doi:10.1126/science.1058453.
-
(2001)
Science
, vol.291
, pp. 2162-2165
-
-
Yin, L.1
Wu, L.2
Wesche, H.3
Arthur, C.D.4
White, J.M.5
Goeddel, D.V.6
-
87
-
-
0032930861
-
Alymphoplasia is caused by a point mutation in the mouse gene encoding Nf-kappa b-inducing kinase
-
doi:10.1038/8780
-
Shinkura R, Kitada K, Matsuda F, Tashiro K, Ikuta K, Suzuki M, et al. Alymphoplasia is caused by a point mutation in the mouse gene encoding Nf-kappa b-inducing kinase. Nat Genet (1999) 22:74-7. doi:10.1038/8780.
-
(1999)
Nat Genet
, vol.22
, pp. 74-77
-
-
Shinkura, R.1
Kitada, K.2
Matsuda, F.3
Tashiro, K.4
Ikuta, K.5
Suzuki, M.6
-
88
-
-
0032127301
-
The lymphotoxin beta receptor controls organogenesis and affinity maturation in peripheral lymphoid tissues
-
doi:10.1016/S1074-7613(00)80588-9
-
Futterer A, Mink K, Luz A, Kosco-Vilbois MH, Pfeffer K. The lymphotoxin beta receptor controls organogenesis and affinity maturation in peripheral lymphoid tissues. Immunity (1998) 9:59-70. doi:10.1016/S1074-7613(00)80588-9.
-
(1998)
Immunity
, vol.9
, pp. 59-70
-
-
Futterer, A.1
Mink, K.2
Luz, A.3
Kosco-Vilbois, M.H.4
Pfeffer, K.5
-
89
-
-
0033537757
-
Limb and skin abnormalities in mice lacking IKKalpha
-
doi:10.1126/science.284.5412.313
-
Takeda K, Takeuchi O, Tsujimura T, Itami S, Adachi O, Kawai T, et al. Limb and skin abnormalities in mice lacking IKKalpha. Science (1999) 284:313-6. doi:10.1126/science.284.5412.313.
-
(1999)
Science
, vol.284
, pp. 313-316
-
-
Takeda, K.1
Takeuchi, O.2
Tsujimura, T.3
Itami, S.4
Adachi, O.5
Kawai, T.6
-
90
-
-
0035910742
-
IkappaB kinase alpha is essential for mature B cell development and function
-
doi:10.1084/jem.193.4.417
-
Kaisho T, Takeda K, Tsujimura T, Kawai T, Nomura F, Terada N, et al. IkappaB kinase alpha is essential for mature B cell development and function. J Exp Med (2001) 193:417-26. doi:10.1084/jem.193.4.417.
-
(2001)
J Exp Med
, vol.193
, pp. 417-426
-
-
Kaisho, T.1
Takeda, K.2
Tsujimura, T.3
Kawai, T.4
Nomura, F.5
Terada, N.6
-
91
-
-
34547535924
-
Regulation of late B cell differentiation by intrinsic IKKalpha-dependent signals
-
doi:10.1073/pnas.0700296104
-
Mills DM, Bonizzi G, Karin M, Rickert RC. Regulation of late B cell differentiation by intrinsic IKKalpha-dependent signals. Proc Natl Acad Sci U S A (2007) 104:6359-64. doi:10.1073/pnas.0700296104.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 6359-6364
-
-
Mills, D.M.1
Bonizzi, G.2
Karin, M.3
Rickert, R.C.4
-
92
-
-
0034596831
-
Attenuation of apoptosis underlies B lymphocyte stimulator enhancement of humoral immune response
-
doi:10.1084/jem.192.7.953
-
Do RK, Hatada E, Lee H, Tourigny MR, Hilbert D, Chen-Kiang S. Attenuation of apoptosis underlies B lymphocyte stimulator enhancement of humoral immune response. J Exp Med (2000) 192:953-64. doi:10.1084/jem.192.7.953.
-
(2000)
J Exp Med
, vol.192
, pp. 953-964
-
-
Do, R.K.1
Hatada, E.2
Lee, H.3
Tourigny, M.R.4
Hilbert, D.5
Chen-Kiang, S.6
-
93
-
-
0034694088
-
BAFF mediates survival of peripheral immature B lymphocytes
-
doi:10.1084/jem.192.10.1453
-
Batten M, Groom J, Cachero TG, Qian F, Schneider P, Tschopp J, et al. BAFF mediates survival of peripheral immature B lymphocytes. J Exp Med (2000) 192:1453-66. doi:10.1084/jem.192.10.1453.
-
(2000)
J Exp Med
, vol.192
, pp. 1453-1466
-
-
Batten, M.1
Groom, J.2
Cachero, T.G.3
Qian, F.4
Schneider, P.5
Tschopp, J.6
-
94
-
-
4544318248
-
The anti-apoptotic factor Bcl-2 can functionally substitute for the B cell survival but not for the marginal zone B cell differentiation activity of BAFF
-
doi:10.1002/eji.200324692
-
Tardivel A, Tinel A, Lens S, Steiner QG, Sauberli E, Wilson A, et al. The anti-apoptotic factor Bcl-2 can functionally substitute for the B cell survival but not for the marginal zone B cell differentiation activity of BAFF. Eur J Immunol (2004) 34:509-18. doi:10.1002/eji.200324692.
-
(2004)
Eur J Immunol
, vol.34
, pp. 509-518
-
-
Tardivel, A.1
Tinel, A.2
Lens, S.3
Steiner, Q.G.4
Sauberli, E.5
Wilson, A.6
-
95
-
-
8444222647
-
B cells expressing Bcl-2 and a signaling-impaired BAFF-specific receptor fail to mature and are deficient in the formation of lymphoid follicles and germinal centers
-
Rahman ZS, Manser T. B cells expressing Bcl-2 and a signaling-impaired BAFF-specific receptor fail to mature and are deficient in the formation of lymphoid follicles and germinal centers. J Immunol (2004) 173:6179-88.
-
(2004)
J Immunol
, vol.173
, pp. 6179-6188
-
-
Rahman, Z.S.1
Manser, T.2
-
96
-
-
8444220390
-
TRAF2 differentially regulates the canonical and noncanonical pathways of NF-kappaB activation in mature B cells
-
doi:10.1016/j.immuni.2004.09.011
-
Grech AP, Amesbury M, Chan T, Gardam S, Basten A, Brink R. TRAF2 differentially regulates the canonical and noncanonical pathways of NF-kappaB activation in mature B cells. Immunity (2004) 21:629-42. doi:10.1016/j.immuni.2004.09.011.
-
(2004)
Immunity
, vol.21
, pp. 629-642
-
-
Grech, A.P.1
Amesbury, M.2
Chan, T.3
Gardam, S.4
Basten, A.5
Brink, R.6
-
97
-
-
34548014506
-
Tumor necrosis factor receptor-associated factor 3 is a critical regulator of B cell homeostasis in secondary lymphoid organs
-
doi:10.1016/j.immuni.2007.07.012
-
Xie P, Stunz LL, Larison KD, Yang B, Bishop GA. Tumor necrosis factor receptor-associated factor 3 is a critical regulator of B cell homeostasis in secondary lymphoid organs. Immunity (2007) 27:253-67. doi:10.1016/j.immuni.2007.07.012.
-
(2007)
Immunity
, vol.27
, pp. 253-267
-
-
Xie, P.1
Stunz, L.L.2
Larison, K.D.3
Yang, B.4
Bishop, G.A.5
-
98
-
-
79954583057
-
Deletion of cIAP1 and cIAP2 in murine B lymphocytes constitutively activates cell survival pathways and inactivates the germinal center response
-
doi:10.1182/blood-2010-10-312793
-
Gardam S, Turner VM, Anderton H, Limaye S, Basten A, Koentgen F, et al. Deletion of cIAP1 and cIAP2 in murine B lymphocytes constitutively activates cell survival pathways and inactivates the germinal center response. Blood (2011) 117:4041-51. doi:10.1182/blood-2010-10-312793.
-
(2011)
Blood
, vol.117
, pp. 4041-4051
-
-
Gardam, S.1
Turner, V.M.2
Anderton, H.3
Limaye, S.4
Basten, A.5
Koentgen, F.6
-
99
-
-
0031463025
-
Early lethality, functional NF-kappaB activation, and increased sensitivity to TNF-induced cell death in TRAF2-deficient mice
-
doi:10.1016/S1074-7613(00)80391-X
-
Yeh WC, Shahinian A, Speiser D, Kraunus J, Billia F, Wakeham A, et al. Early lethality, functional NF-kappaB activation, and increased sensitivity to TNF-induced cell death in TRAF2-deficient mice. Immunity (1997) 7:715-25. doi:10.1016/S1074-7613(00)80391-X.
-
(1997)
Immunity
, vol.7
, pp. 715-725
-
-
Yeh, W.C.1
Shahinian, A.2
Speiser, D.3
Kraunus, J.4
Billia, F.5
Wakeham, A.6
-
100
-
-
0030292777
-
Targeted disruption of TRAF3 leads to postnatal lethality and defective T-dependent immune responses
-
doi:10.1016/S1074-7613(00)80497-5
-
Xu Y, Cheng G, Baltimore D. Targeted disruption of TRAF3 leads to postnatal lethality and defective T-dependent immune responses. Immunity (1996) 5:407-15. doi:10.1016/S1074-7613(00)80497-5.
-
(1996)
Immunity
, vol.5
, pp. 407-415
-
-
Xu, Y.1
Cheng, G.2
Baltimore, D.3
-
101
-
-
78149369048
-
Non-canonical NF-kappaB activation and abnormal B cell accumulation in mice expressing ubiquitin protein ligase-inactive c-IAP2
-
doi:10.1371/journal.pbio.1000518
-
Conze DB, Zhao Y, Ashwell JD. Non-canonical NF-kappaB activation and abnormal B cell accumulation in mice expressing ubiquitin protein ligase-inactive c-IAP2. PLoS Biol (2010) 8:e1000518. doi:10.1371/journal.pbio.1000518.
-
(2010)
PLoS Biol
, vol.8
-
-
Conze, D.B.1
Zhao, Y.2
Ashwell, J.D.3
-
102
-
-
78049456523
-
The germinal center reaction
-
doi:10.1016/j.jaci.2010.09.007
-
Gatto D, Brink R. The germinal center reaction. J Allergy Clin Immunol (2010) 126:898-907. doi:10.1016/j.jaci.2010.09.007.
-
(2010)
J Allergy Clin Immunol
, vol.126
, pp. 898-907
-
-
Gatto, D.1
Brink, R.2
-
103
-
-
0142188050
-
Normal induction but attenuated progression of germinal center responses in BAFF and BAFF-R signaling-deficient mice
-
doi:10.1084/jem.20030495
-
Rahman ZS, Rao SP, Kalled SL, Manser T. Normal induction but attenuated progression of germinal center responses in BAFF and BAFF-R signaling-deficient mice. J Exp Med (2003) 198:1157-69. doi:10.1084/jem.20030495.
-
(2003)
J Exp Med
, vol.198
, pp. 1157-1169
-
-
Rahman, Z.S.1
Rao, S.P.2
Kalled, S.L.3
Manser, T.4
-
104
-
-
0038446862
-
Cutting edge: germinal centers formed in the absence of B cell-activating factor belonging to the TNF family exhibit impaired maturation and function
-
Vora KA, Wang LC, Rao SP, Liu ZY, Majeau GR, Cutler AH, et al. Cutting edge: germinal centers formed in the absence of B cell-activating factor belonging to the TNF family exhibit impaired maturation and function. J Immunol (2003) 171:547-51.
-
(2003)
J Immunol
, vol.171
, pp. 547-551
-
-
Vora, K.A.1
Wang, L.C.2
Rao, S.P.3
Liu, Z.Y.4
Majeau, G.R.5
Cutler, A.H.6
-
105
-
-
77953020258
-
Activation of B cells by antigens on follicular dendritic cells
-
doi:10.1016/j.it.2010.03.002
-
El Shikh ME, El Sayed RM, Sukumar S, Szakal AK, Tew JG. Activation of B cells by antigens on follicular dendritic cells. Trends Immunol (2010) 31:205-11. doi:10.1016/j.it.2010.03.002.
-
(2010)
Trends Immunol
, vol.31
, pp. 205-211
-
-
El Shikh, M.E.1
El Sayed, R.M.2
Sukumar, S.3
Szakal, A.K.4
Tew, J.G.5
-
106
-
-
60749110961
-
Altered BAFF-receptor signaling and additional modifier loci contribute to systemic autoimmunity in A/WySnJ mice
-
doi:10.1002/eji.200838569
-
Mayne CG, Nashold FE, Sasaki Y, Hayes CE. Altered BAFF-receptor signaling and additional modifier loci contribute to systemic autoimmunity in A/WySnJ mice. Eur J Immunol (2009) 39:589-99. doi:10.1002/eji.200838569.
-
(2009)
Eur J Immunol
, vol.39
, pp. 589-599
-
-
Mayne, C.G.1
Nashold, F.E.2
Sasaki, Y.3
Hayes, C.E.4
-
107
-
-
0035881959
-
Essential role of RelB in germinal center and marginal zone formation and proper expression of homing chemokines
-
Weih DS, Yilmaz ZB, Weih F. Essential role of RelB in germinal center and marginal zone formation and proper expression of homing chemokines. J Immunol (2001) 167:1909-19.
-
(2001)
J Immunol
, vol.167
, pp. 1909-1919
-
-
Weih, D.S.1
Yilmaz, Z.B.2
Weih, F.3
-
108
-
-
0034662002
-
Abnormal immune function of hemopoietic cells from alymphoplasia (aly) mice, a natural strain with mutant NF-kappa B-inducing kinase
-
Yamada T, Mitani T, Yorita K, Uchida D, Matsushima A, Iwamasa K, et al. Abnormal immune function of hemopoietic cells from alymphoplasia (aly) mice, a natural strain with mutant NF-kappa B-inducing kinase. J Immunol (2000) 165:804-12.
-
(2000)
J Immunol
, vol.165
, pp. 804-812
-
-
Yamada, T.1
Mitani, T.2
Yorita, K.3
Uchida, D.4
Matsushima, A.5
Iwamasa, K.6
-
109
-
-
48749090228
-
Essential cytoplasmic translocation of a cytokine receptor-assembled signaling complex
-
doi:10.1126/science.1157340
-
Matsuzawa A, Tseng PH, Vallabhapurapu S, Luo JL, Zhang W, Wang H, et al. Essential cytoplasmic translocation of a cytokine receptor-assembled signaling complex. Science (2008) 321:663-8. doi:10.1126/science.1157340.
-
(2008)
Science
, vol.321
, pp. 663-668
-
-
Matsuzawa, A.1
Tseng, P.H.2
Vallabhapurapu, S.3
Luo, J.L.4
Zhang, W.5
Wang, H.6
-
110
-
-
33748441252
-
Alternative and classical NF-kappa B signaling retain autoreactive B cells in the splenic marginal zone and result in lupus-like disease
-
doi:10.1016/j.immuni.2006.07.010
-
Enzler T, Bonizzi G, Silverman GJ, Otero DC, Widhopf GF, Anzelon-Mills A, et al. Alternative and classical NF-kappa B signaling retain autoreactive B cells in the splenic marginal zone and result in lupus-like disease. Immunity (2006) 25:403-15. doi:10.1016/j.immuni.2006.07.010.
-
(2006)
Immunity
, vol.25
, pp. 403-415
-
-
Enzler, T.1
Bonizzi, G.2
Silverman, G.J.3
Otero, D.C.4
Widhopf, G.F.5
Anzelon-Mills, A.6
-
111
-
-
49949151852
-
TACI, an enigmatic BAFF/APRIL receptor, with new unappreciated biochemical and biological properties
-
doi:10.1016/j.cytogfr.2008.04.006
-
Mackay F, Schneider P. TACI, an enigmatic BAFF/APRIL receptor, with new unappreciated biochemical and biological properties. Cytokine Growth Factor Rev (2008) 19:263-76. doi:10.1016/j.cytogfr.2008.04.006.
-
(2008)
Cytokine Growth Factor Rev
, vol.19
, pp. 263-276
-
-
Mackay, F.1
Schneider, P.2
-
112
-
-
38949206321
-
TACI, unlike BAFF-R, is solely activated by oligomeric BAFF and APRIL to support survival of activated B cells and plasmablasts
-
doi:10.1182/blood-2007-09-110874
-
Bossen C, Cachero TG, Tardivel A, Ingold K, Willen L, Dobles M, et al. TACI, unlike BAFF-R, is solely activated by oligomeric BAFF and APRIL to support survival of activated B cells and plasmablasts. Blood (2008) 111:1004-12. doi:10.1182/blood-2007-09-110874.
-
(2008)
Blood
, vol.111
, pp. 1004-1012
-
-
Bossen, C.1
Cachero, T.G.2
Tardivel, A.3
Ingold, K.4
Willen, L.5
Dobles, M.6
-
113
-
-
69549128384
-
B-cell activating factor receptor deficiency is associated with an adult-onset antibody deficiency syndrome in humans
-
doi:10.1073/pnas.0903543106
-
Warnatz K, Salzer U, Rizzi M, Fischer B, Gutenberger S, Bohm J, et al. B-cell activating factor receptor deficiency is associated with an adult-onset antibody deficiency syndrome in humans. Proc Natl Acad Sci U S A (2009) 106:13945-50. doi:10.1073/pnas.0903543106.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 13945-13950
-
-
Warnatz, K.1
Salzer, U.2
Rizzi, M.3
Fischer, B.4
Gutenberger, S.5
Bohm, J.6
-
114
-
-
0035013708
-
Marginal zone and B1 B cells unite in the early response against T-independent blood-borne particulate antigens
-
doi:10.1016/S1074-7613(01)00129-7
-
Martin F, Oliver AM, Kearney JF. Marginal zone and B1 B cells unite in the early response against T-independent blood-borne particulate antigens. Immunity (2001) 14:617-29. doi:10.1016/S1074-7613(01)00129-7.
-
(2001)
Immunity
, vol.14
, pp. 617-629
-
-
Martin, F.1
Oliver, A.M.2
Kearney, J.F.3
-
115
-
-
81355127378
-
Staying alive: regulation of plasma cell survival
-
doi:10.1016/j.it.2011.09.001
-
Tangye SG. Staying alive: regulation of plasma cell survival. Trends Immunol (2011) 32:595-602. doi:10.1016/j.it.2011.09.001.
-
(2011)
Trends Immunol
, vol.32
, pp. 595-602
-
-
Tangye, S.G.1
-
116
-
-
44849097480
-
Cutting edge: the dependence of plasma cells and independence of memory B cells on BAFF and APRIL
-
Benson MJ, Dillon SR, Castigli E, Geha RS, Xu S, Lam KP, et al. Cutting edge: the dependence of plasma cells and independence of memory B cells on BAFF and APRIL. J Immunol (2008) 180:3655-9.
-
(2008)
J Immunol
, vol.180
, pp. 3655-3659
-
-
Benson, M.J.1
Dillon, S.R.2
Castigli, E.3
Geha, R.S.4
Xu, S.5
Lam, K.P.6
-
117
-
-
41949138741
-
APRIL is critical for plasmablast survival in the bone marrow and poorly expressed by early-life bone marrow stromal cells
-
doi:10.1182/blood-2007-09-110858
-
Belnoue E, Pihlgren M, McGaha TL, Tougne C, Rochat AF, Bossen C, et al. APRIL is critical for plasmablast survival in the bone marrow and poorly expressed by early-life bone marrow stromal cells. Blood (2008) 111:2755-64. doi:10.1182/blood-2007-09-110858.
-
(2008)
Blood
, vol.111
, pp. 2755-2764
-
-
Belnoue, E.1
Pihlgren, M.2
McGaha, T.L.3
Tougne, C.4
Rochat, A.F.5
Bossen, C.6
-
118
-
-
80051875762
-
Production of the plasma-cell survival factor a proliferation-inducing ligand (APRIL) peaks in myeloid precursor cells from human bone marrow
-
doi:10.1182/blood-2011-01-332940
-
Matthes T, Dunand-Sauthier I, Santiago-Raber ML, Krause KH, Donze O, Passweg J, et al. Production of the plasma-cell survival factor a proliferation-inducing ligand (APRIL) peaks in myeloid precursor cells from human bone marrow. Blood (2011) 118:1838-44. doi:10.1182/blood-2011-01-332940.
-
(2011)
Blood
, vol.118
, pp. 1838-1844
-
-
Matthes, T.1
Dunand-Sauthier, I.2
Santiago-Raber, M.L.3
Krause, K.H.4
Donze, O.5
Passweg, J.6
-
119
-
-
0347285357
-
BCMA is essential for the survival of long-lived bone marrow plasma cells
-
doi:10.1084/jem.20031330
-
O'Connor BP, Raman VS, Erickson LD, Cook WJ, Weaver LK, Ahonen C, et al. BCMA is essential for the survival of long-lived bone marrow plasma cells. J Exp Med (2004) 199:91-8. doi:10.1084/jem.20031330.
-
(2004)
J Exp Med
, vol.199
, pp. 91-98
-
-
O'Connor, B.P.1
Raman, V.S.2
Erickson, L.D.3
Cook, W.J.4
Weaver, L.K.5
Ahonen, C.6
-
120
-
-
34547562418
-
Frequent engagement of the classical and alternative NF-kappaB pathways by diverse genetic abnormalities in multiple myeloma
-
doi:10.1016/j.ccr.2007.07.004
-
Annunziata CM, Davis RE, Demchenko Y, Bellamy W, Gabrea A, Zhan F, et al. Frequent engagement of the classical and alternative NF-kappaB pathways by diverse genetic abnormalities in multiple myeloma. Cancer Cell (2007) 12:115-30. doi:10.1016/j.ccr.2007.07.004.
-
(2007)
Cancer Cell
, vol.12
, pp. 115-130
-
-
Annunziata, C.M.1
Davis, R.E.2
Demchenko, Y.3
Bellamy, W.4
Gabrea, A.5
Zhan, F.6
-
121
-
-
77951719556
-
Classical and/or alternative NF-kappaB pathway activation in multiple myeloma
-
doi:10.1182/blood-2009-09-243535
-
Demchenko YN, Glebov OK, Zingone A, Keats JJ, Bergsagel PL, Kuehl WM. Classical and/or alternative NF-kappaB pathway activation in multiple myeloma. Blood (2010) 115:3541-52. doi:10.1182/blood-2009-09-243535.
-
(2010)
Blood
, vol.115
, pp. 3541-3552
-
-
Demchenko, Y.N.1
Glebov, O.K.2
Zingone, A.3
Keats, J.J.4
Bergsagel, P.L.5
Kuehl, W.M.6
-
122
-
-
34547660308
-
Promiscuous mutations activate the noncanonical NF-kappaB pathway in multiple myeloma
-
doi:10.1016/j.ccr.2007.07.003
-
Keats JJ, Fonseca R, Chesi M, Schop R, Baker A, Chng WJ, et al. Promiscuous mutations activate the noncanonical NF-kappaB pathway in multiple myeloma. Cancer Cell (2007) 12:131-44. doi:10.1016/j.ccr.2007.07.003.
-
(2007)
Cancer Cell
, vol.12
, pp. 131-144
-
-
Keats, J.J.1
Fonseca, R.2
Chesi, M.3
Schop, R.4
Baker, A.5
Chng, W.J.6
-
123
-
-
84881247286
-
The BAFF/APRIL system: emerging functions beyond B cell biology and autoimmunity
-
doi:10.1016/j.cytogfr.2013.04.003
-
Vincent FB, Saulep-Easton D, Figgett WA, Fairfax KA, Mackay F. The BAFF/APRIL system: emerging functions beyond B cell biology and autoimmunity. Cytokine Growth Factor Rev (2013) 24:203-15. doi:10.1016/j.cytogfr.2013.04.003.
-
(2013)
Cytokine Growth Factor Rev
, vol.24
, pp. 203-215
-
-
Vincent, F.B.1
Saulep-Easton, D.2
Figgett, W.A.3
Fairfax, K.A.4
Mackay, F.5
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