Identification of a novel receptor for B lymphocyte stimulator that is mutated in a mouse strain with severe B cell deficiency

Current Biology

Volumn 11, Issue 19, 2001, Pages 1547-1552

  Yan, Minhong ^a   Brady, John Ridgway ^a   Chan, Betty ^a   Lee, Wyne P ^a   Hsu, Benjamin ^b   Harless, Susan ^b   Cancro, Michael ^b   Grewal, Iqbal S ^a   Dixit, Vishva M ^a  

^a GENENTECH INC   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

B LYMPHOCYTE RECEPTOR; BINDING AFFINITY; GENE DISRUPTION; GENE IDENTIFICATION; GENE INSERTION; GENE KNOCKOUT; GENETIC REGULATION; IMMUNE RESPONSE; MOUSE; PHENOTYPE;

EID: 0035797908     PISSN: 09609822     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-9822(01)00481-X     Document Type: Article

References (24)

1. BLyS: Member of the tumor necrosis factor family and B lymphocyte stimulator
2. TALL-1 is a novel member of the TNF family that is down-regulated by mitogens
3. BAFF, a novel ligand of the tumor necrosis factor family, stimulates B cell growth
4. Identification and characterization of a novel cytokine, THANK, a TNF homologue that activates apoptosis, nuclear factor-kappaB, and c-Jun NH2-terminal kinase
5. TACI and BCMA are receptors for a TNF homologue implicated in B-cell autoimmune disease
6. Identification of a receptor for BLyS demonstrates a crucial role in humoral immunity
7. Tumor necrosis factor (TNF) receptor superfamily member TACI is a high affinity receptor for TNF family members APRIL and BLyS
8. APRIL, a new ligand of the tumor necrosis factor family, stimulates tumor cell growth
9. Interaction of the TNF homologues BLyS and APRIL with the TNF receptor homologues BCMA and TACI
10. APRIL and TALL-I and receptors BCMA and TACI: System for regulating humoral immunity
11. Activation and accumulation of B cells in TACI-deficient mice
12. Regulation of the T-independent humoral response by TACI
13. B-cell maturation protein, which binds the tumor necrosis factor family members BAFF and APRIL, is dispensable for humoral immune responses
14. The kit ligand: A cell surface molecule altered in steel mutant fibroblasts
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